Guide to the Human Genome
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Search of human proteins with 45333906

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45333906 COMM domain containing 6 isoform b [Homo sapiens]
         (85 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45333906 COMM domain containing 6 isoform b [Homo sapiens]         173   2e-44
gi|45333909 COMM domain containing 6 isoform a [Homo sapiens]         164   1e-41
gi|8923458 COMM domain containing 8 [Homo sapiens]                     41   2e-04
gi|151101369 COMM domain containing 7 isoform 1 [Homo sapiens]         39   0.001
gi|151101367 COMM domain containing 7 isoform 2 [Homo sapiens]         39   0.001
gi|124487382 COMM domain containing 5 [Homo sapiens]                   28   1.2  
gi|154800418 COMM domain containing 5 [Homo sapiens]                   28   1.2  
gi|19923430 COMM domain containing 5 [Homo sapiens]                    28   1.2  
gi|169166962 PREDICTED: similar to COMM domain containing 5 [Hom...    27   3.5  
gi|169166771 PREDICTED: similar to COMM domain containing 5 [Hom...    27   3.5  
gi|169166418 PREDICTED: similar to COMM domain containing 5 [Hom...    27   3.5  
gi|9994185 RNA binding motif protein 7 [Homo sapiens]                  27   4.5  
gi|21361661 COMM domain containing 4 [Homo sapiens]                    27   4.5  
gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]                     26   5.9  
gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]                     26   5.9  
gi|4758416 golgi-specific brefeldin A resistant guanine nucleoti...    26   7.7  
gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]         26   7.7  
gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]         26   7.7  

>gi|45333906 COMM domain containing 6 isoform b [Homo sapiens]
          Length = 85

 Score =  173 bits (439), Expect = 2e-44
 Identities = 85/85 (100%), Positives = 85/85 (100%)

Query: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60
          MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC
Sbjct: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60

Query: 61 FEMTIPQFQNFYRQFKEIAAVIETV 85
          FEMTIPQFQNFYRQFKEIAAVIETV
Sbjct: 61 FEMTIPQFQNFYRQFKEIAAVIETV 85


>gi|45333909 COMM domain containing 6 isoform a [Homo sapiens]
          Length = 98

 Score =  164 bits (415), Expect = 1e-41
 Identities = 85/98 (86%), Positives = 85/98 (86%), Gaps = 13/98 (13%)

Query: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60
          MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC
Sbjct: 1  MEASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKC 60

Query: 61 FEMTIPQFQ-------------NFYRQFKEIAAVIETV 85
          FEMTIPQFQ             NFYRQFKEIAAVIETV
Sbjct: 61 FEMTIPQFQPQLLATSSLLSASNFYRQFKEIAAVIETV 98


>gi|8923458 COMM domain containing 8 [Homo sapiens]
          Length = 183

 Score = 40.8 bits (94), Expect = 2e-04
 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 1/65 (1%)

Query: 18  QLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQNFYRQFKE 77
           QL DF W++ +A+SSD   +L+ P +++ L V + +G+VK    EM+  + QN  +  + 
Sbjct: 116 QLQDFDWQVKLALSSDKIAALRMPLLSLHLDVKE-NGEVKPYSIEMSREELQNLIQSLEA 174

Query: 78  IAAVI 82
              V+
Sbjct: 175 ANKVV 179


>gi|151101369 COMM domain containing 7 isoform 1 [Homo sapiens]
          Length = 200

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)

Query: 17  NQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQNFYRQFK 76
           NQL+D +WK G+   S     +   ++ + L V     Q +    E+T+PQF +F  + +
Sbjct: 132 NQLIDMEWKFGVTSGSSELEKVGSIFLQLKL-VVKKGNQTENVYIELTLPQFYSFLHEME 190

Query: 77  EIAAVIE 83
            +   +E
Sbjct: 191 RVRTSME 197


>gi|151101367 COMM domain containing 7 isoform 2 [Homo sapiens]
          Length = 199

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 18/67 (26%), Positives = 33/67 (49%), Gaps = 1/67 (1%)

Query: 17  NQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQNFYRQFK 76
           NQL+D +WK G+   S     +   ++ + L V     Q +    E+T+PQF +F  + +
Sbjct: 131 NQLIDMEWKFGVTSGSSELEKVGSIFLQLKL-VVKKGNQTENVYIELTLPQFYSFLHEME 189

Query: 77  EIAAVIE 83
            +   +E
Sbjct: 190 RVRTSME 196


>gi|124487382 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DF+W++ +A+S+        P V + LK++D S       FE+   +FQ
Sbjct: 152 VADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAY----RFEVPTAKFQ 198


>gi|154800418 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DF+W++ +A+S+        P V + LK++D S       FE+   +FQ
Sbjct: 152 VADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAY----RFEVPTAKFQ 198


>gi|19923430 COMM domain containing 5 [Homo sapiens]
          Length = 224

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DF+W++ +A+S+        P V + LK++D S       FE+   +FQ
Sbjct: 152 VADFRWRVDVAISTSALARSLQPSVLMQLKLSDGSAY----RFEVPTAKFQ 198


>gi|169166962 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DFQW + + +S+        P V + LK++D         FE+ I +FQ
Sbjct: 201 VADFQWWVDVTISTSALARFLQPRVLMQLKLSDGLAY----RFEVPIAKFQ 247


>gi|169166771 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DFQW + + +S+        P V + LK++D         FE+ I +FQ
Sbjct: 201 VADFQWWVDVTISTSALARFLQPRVLMQLKLSDGLAY----RFEVPIAKFQ 247


>gi|169166418 PREDICTED: similar to COMM domain containing 5 [Homo
           sapiens]
          Length = 273

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/51 (29%), Positives = 25/51 (49%), Gaps = 4/51 (7%)

Query: 19  LVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           + DFQW + + +S+        P V + LK++D         FE+ I +FQ
Sbjct: 201 VADFQWWVDVTISTSALARFLQPRVLMQLKLSDGLAY----RFEVPIAKFQ 247


>gi|9994185 RNA binding motif protein 7 [Homo sapiens]
          Length = 266

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 13/43 (30%), Positives = 19/43 (44%)

Query: 2   EASSEPPLDAKSDVTNQLVDFQWKLGMAVSSDTCRSLKYPYVA 44
           ++   P + + S   NQ    QW+ G   S    R   YPY+A
Sbjct: 167 QSGFSPSVQSHSHSFNQSSSSQWRQGTPSSQRKVRMNSYPYLA 209


>gi|21361661 COMM domain containing 4 [Homo sapiens]
          Length = 199

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 15/70 (21%), Positives = 34/70 (48%), Gaps = 1/70 (1%)

Query: 17  NQLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVADHSG-QVKTKCFEMTIPQFQNFYRQF 75
           N+L    W++   +SS   +S++ P V + L+VA   G   +     ++  +FQ    + 
Sbjct: 129 NRLAGVGWRVDYTLSSSLLQSVEEPMVHLRLEVAAAPGTPAQPVAMSLSADKFQVLLAEL 188

Query: 76  KEIAAVIETV 85
           K+   ++ ++
Sbjct: 189 KQAQTLMSSL 198


>gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]
          Length = 586

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 11/29 (37%), Positives = 20/29 (68%)

Query: 10  DAKSDVTNQLVDFQWKLGMAVSSDTCRSL 38
           DA+ D+  QLV+F +   ++V+S+  +SL
Sbjct: 89  DAEPDIIEQLVEFAYTARISVNSNNVQSL 117


>gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]
          Length = 564

 Score = 26.2 bits (56), Expect = 5.9
 Identities = 11/29 (37%), Positives = 20/29 (68%)

Query: 10 DAKSDVTNQLVDFQWKLGMAVSSDTCRSL 38
          DA+ D+  QLV+F +   ++V+S+  +SL
Sbjct: 67 DAEPDIIEQLVEFAYTARISVNSNNVQSL 95


>gi|4758416 golgi-specific brefeldin A resistant guanine nucleotide
           exchange factor 1 [Homo sapiens]
          Length = 1859

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 2/39 (5%)

Query: 31  SSDTCRSLKYPYVAVMLKVADHSGQVKTKCFEMTIPQFQ 69
           +SD C SL Y    +ML    H+  V+ +   MT+ +F+
Sbjct: 819 NSDACFSLAY--AVIMLNTDQHNHNVRKQNAPMTLEEFR 855


>gi|156416007 COMM domain containing 9 isoform 2 [Homo sapiens]
          Length = 156

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 9/34 (26%), Positives = 19/34 (55%)

Query: 18  QLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVAD 51
           +LVD  W++ +  SSD+   +  P   + +K+ +
Sbjct: 80  RLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 113


>gi|156416005 COMM domain containing 9 isoform 1 [Homo sapiens]
          Length = 198

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 9/34 (26%), Positives = 19/34 (55%)

Query: 18  QLVDFQWKLGMAVSSDTCRSLKYPYVAVMLKVAD 51
           +LVD  W++ +  SSD+   +  P   + +K+ +
Sbjct: 122 RLVDLDWRVDIKTSSDSISRMAVPTCLLQMKIQE 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.130    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 2,714,506
Number of Sequences: 37866
Number of extensions: 80088
Number of successful extensions: 142
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 125
Number of HSP's gapped (non-prelim): 18
length of query: 85
length of database: 18,247,518
effective HSP length: 57
effective length of query: 28
effective length of database: 16,089,156
effective search space: 450496368
effective search space used: 450496368
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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