Guide to the Human Genome
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Search of human proteins with 4507751

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507751 thymidylate synthase [Homo sapiens]
         (313 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507751 thymidylate synthase [Homo sapiens]                        651   0.0  
gi|5174421 copine 6 [Homo sapiens]                                     33   0.43 
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]             29   4.7  
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ...    29   4.7  
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ...    29   4.7  
gi|229089140 leucine rich repeat containing 24 [Homo sapiens]          29   6.2  
gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo s...    28   8.0  
gi|41872646 cullin 7 [Homo sapiens]                                    28   8.0  
gi|51944950 phosducin-like 2 [Homo sapiens]                            28   8.0  

>gi|4507751 thymidylate synthase [Homo sapiens]
          Length = 313

 Score =  651 bits (1680), Expect = 0.0
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60
           MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG
Sbjct: 1   MPVAGSELPRRPLPPAAQERDAEPRPPHGELQYLGQIQHILRCGVRKDDRTGTGTLSVFG 60

Query: 61  MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120
           MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS
Sbjct: 61  MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS 120

Query: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180
           LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC
Sbjct: 121 LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC 180

Query: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240
           AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI
Sbjct: 181 AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI 240

Query: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300
           TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG
Sbjct: 241 TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLRILRKVEKIDDFKAEDFQIEG 300

Query: 301 YNPHPTIKMEMAV 313
           YNPHPTIKMEMAV
Sbjct: 301 YNPHPTIKMEMAV 313


>gi|5174421 copine 6 [Homo sapiens]
          Length = 557

 Score = 32.7 bits (73), Expect = 0.43
 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 2/51 (3%)

Query: 109 WDANGSRDFLDSLG--FSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQG 157
           +D++G  DF+      F   +EG   P    QW     +YRD + +Y   G
Sbjct: 230 YDSSGKHDFIGEFTSTFQEMQEGTANPGQEMQWDCINPKYRDKKKNYKSSG 280


>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
          Length = 1950

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 5/57 (8%)

Query: 100 ELSSKGVKIWDANGSRDFLDSLGFSTREEGDLG-PVYGFQWRHFGAEYRDMESDYSG 155
           ELS  G+K+   + S D  ++LGF   + G  G    G  W     E    +SD SG
Sbjct: 376 ELSENGIKVTRESSSSDLAENLGFGLEKFGQKGFGTSGSGWN----EQSSSKSDVSG 428


>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
           sapiens]
          Length = 2134

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 5/57 (8%)

Query: 100 ELSSKGVKIWDANGSRDFLDSLGFSTREEGDLG-PVYGFQWRHFGAEYRDMESDYSG 155
           ELS  G+K+   + S D  ++LGF   + G  G    G  W     E    +SD SG
Sbjct: 387 ELSENGIKVTRESSSSDLAENLGFGLEKFGQKGFGTSGSGWN----EQSSSKSDVSG 439


>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
           sapiens]
          Length = 2134

 Score = 29.3 bits (64), Expect = 4.7
 Identities = 19/57 (33%), Positives = 26/57 (45%), Gaps = 5/57 (8%)

Query: 100 ELSSKGVKIWDANGSRDFLDSLGFSTREEGDLG-PVYGFQWRHFGAEYRDMESDYSG 155
           ELS  G+K+   + S D  ++LGF   + G  G    G  W     E    +SD SG
Sbjct: 387 ELSENGIKVTRESSSSDLAENLGFGLEKFGQKGFGTSGSGWN----EQSSSKSDVSG 439


>gi|229089140 leucine rich repeat containing 24 [Homo sapiens]
          Length = 513

 Score = 28.9 bits (63), Expect = 6.2
 Identities = 11/25 (44%), Positives = 16/25 (64%)

Query: 9   PRRPLPPAAQERDAEPRPPHGELQY 33
           P +P PPAA+   +EPRP  G + +
Sbjct: 372 PAQPPPPAARPAGSEPRPEAGSMAF 396


>gi|239735605 leucine rich repeat containing 36 isoform 1 [Homo
           sapiens]
          Length = 754

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 3/56 (5%)

Query: 240 ITGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPK---LRILRKVEKIDDFK 292
           IT LK   ++ +L D ++Y N+I  L    + +P PF K   LR+   V K  D++
Sbjct: 62  ITSLKGIQYLCSLQDLNLYYNNIPSLVEVSRLQPLPFLKELDLRLNPVVRKDTDYR 117


>gi|41872646 cullin 7 [Homo sapiens]
          Length = 1698

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 10/17 (58%), Positives = 15/17 (88%)

Query: 260 NHIEPLKIQLQREPRPF 276
           N ++PL +QLQR+P+PF
Sbjct: 650 NKVKPLLLQLQRQPQPF 666


>gi|51944950 phosducin-like 2 [Homo sapiens]
          Length = 241

 Score = 28.5 bits (62), Expect = 8.0
 Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 3/45 (6%)

Query: 260 NHIEPLKIQLQREP--RPFPKLRILRKVEKIDDFKAEDFQ-IEGY 301
           + IE + ++LQ+E   +PF K+ + +  E  D+F  ED Q +E Y
Sbjct: 28  DEIEEMVLRLQKEAMVKPFEKMTLAQLKEAEDEFDEEDMQAVETY 72


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.141    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,517,699
Number of Sequences: 37866
Number of extensions: 648426
Number of successful extensions: 1775
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1772
Number of HSP's gapped (non-prelim): 9
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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