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Search of human proteins with 4505775
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505775 solute carrier family 25 member 3 isoform b
precursor [Homo sapiens]
(361 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505775 solute carrier family 25 member 3 isoform b precursor... 735 0.0
gi|47132595 solute carrier family 25 member 3 isoform b precurso... 735 0.0
gi|6031192 solute carrier family 25 member 3 isoform a precursor... 714 0.0
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 89 8e-18
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 89 8e-18
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 89 8e-18
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 83 3e-16
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 80 3e-15
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 78 1e-14
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 78 1e-14
gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 76 4e-14
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 76 5e-14
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 76 5e-14
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 76 5e-14
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 76 5e-14
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 76 5e-14
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 76 5e-14
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 76 5e-14
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 75 7e-14
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 75 7e-14
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 75 1e-13
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 73 5e-13
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 72 8e-13
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 71 1e-12
gi|11225256 uncoupling protein 1 [Homo sapiens] 71 2e-12
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 70 3e-12
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 70 3e-12
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 70 3e-12
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 69 7e-12
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 68 1e-11
>gi|4505775 solute carrier family 25 member 3 isoform b precursor
[Homo sapiens]
Length = 361
Score = 735 bits (1897), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS
Sbjct: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60
Query: 61 AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120
AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK
Sbjct: 61 AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120
Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180
GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA
Sbjct: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180
Query: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT
Sbjct: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
Query: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300
VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL
Sbjct: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300
Query: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360
VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT
Sbjct: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360
Query: 361 Q 361
Q
Sbjct: 361 Q 361
>gi|47132595 solute carrier family 25 member 3 isoform b precursor
[Homo sapiens]
Length = 361
Score = 735 bits (1897), Expect = 0.0
Identities = 361/361 (100%), Positives = 361/361 (100%)
Query: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS
Sbjct: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEYSCEFGS 60
Query: 61 AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120
AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK
Sbjct: 61 AKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAK 120
Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180
GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA
Sbjct: 121 GWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALA 180
Query: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT
Sbjct: 181 PMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
Query: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300
VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL
Sbjct: 241 VEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL 300
Query: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360
VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT
Sbjct: 301 VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGLT 360
Query: 361 Q 361
Q
Sbjct: 361 Q 361
>gi|6031192 solute carrier family 25 member 3 isoform a precursor
[Homo sapiens]
Length = 362
Score = 714 bits (1842), Expect = 0.0
Identities = 349/362 (96%), Positives = 357/362 (98%), Gaps = 1/362 (0%)
Query: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE-YSCEFG 59
MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEE YSC++G
Sbjct: 1 MFSSVAHLARANPFNTPHLQLVHDGLGDLRSSSPGPTGQPRRPRNLAAAAVEEQYSCDYG 60
Query: 60 SAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 119
S +++ LCG GG++SCG THTA+VPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA
Sbjct: 61 SGRFFILCGLGGIISCGTTHTALVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLA 120
Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL
Sbjct: 121 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 180
Query: 180 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 239
APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER
Sbjct: 181 APMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFER 240
Query: 240 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 299
TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS
Sbjct: 241 TVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS 300
Query: 300 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 359
LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL
Sbjct: 301 LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKLGL 360
Query: 360 TQ 361
TQ
Sbjct: 361 TQ 362
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 88.6 bits (218), Expect = 8e-18
Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 38/292 (13%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLAKG 121
G +S +T + P D++K R Q+ DP KY GI L+E+G KG
Sbjct: 22 GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKG 81
Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIALA 180
P + G +F +E+ + ++ + Y R S++ A A + +
Sbjct: 82 HVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 181 PMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
P++ + R Q +P NTLR A MY+ EG + FYKG+AP + PY ++F+C+
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197
Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD-------------- 284
+++ LYK+ +P +E K E L + G AGV +++P D
Sbjct: 198 -SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 285 -SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 333
+ + + KG A VL++ G G +KGL ++ T +F Y+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 161 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 210
T +A + S AL +P + K+R Q Q + + A+ ++ +EE
Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
Query: 211 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 270
G AF+KG P + I Y ++F FE E +++ V R + V FV G
Sbjct: 74 GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
Query: 271 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 318
+A + HP D V + L G+ + + G + +KGL +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
Query: 319 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 357
I I LQ+ Y S+K ++ P + E+L+ L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 88.6 bits (218), Expect = 8e-18
Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 38/292 (13%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLAKG 121
G +S +T + P D++K R Q+ DP KY GI L+E+G KG
Sbjct: 22 GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKG 81
Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIALA 180
P + G +F +E+ + ++ + Y R S++ A A + +
Sbjct: 82 HVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 181 PMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
P++ + R Q +P NTLR A MY+ EG + FYKG+AP + PY ++F+C+
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197
Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD-------------- 284
+++ LYK+ +P +E K E L + G AGV +++P D
Sbjct: 198 -SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 285 -SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 333
+ + + KG A VL++ G G +KGL ++ T +F Y+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 161 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 210
T +A + S AL +P + K+R Q Q + + A+ ++ +EE
Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
Query: 211 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 270
G AF+KG P + I Y ++F FE E +++ V R + V FV G
Sbjct: 74 GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
Query: 271 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 318
+A + HP D V + L G+ + + G + +KGL +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
Query: 319 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 357
I I LQ+ Y S+K ++ P + E+L+ L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 88.6 bits (218), Expect = 8e-18
Identities = 78/292 (26%), Positives = 130/292 (44%), Gaps = 38/292 (13%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQV--------DPQ-KYKGIFNGFSVTLKEDGVRGLAKG 121
G +S +T + P D++K R Q+ DP KY GI L+E+G KG
Sbjct: 22 GSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKG 81
Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT-SLYLAASASAEFFADIALA 180
P + G +F +E+ + ++ + Y R S++ A A + +
Sbjct: 82 HVPAQILSIGYGAVQFLSFEML----TELVHRGSVYDAREFSVHFVCGGLAACMATLTVH 137
Query: 181 PMEAAKVRI--QTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
P++ + R Q +P NTLR A MY+ EG + FYKG+AP + PY ++F+C+
Sbjct: 138 PVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYS 197
Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD-------------- 284
+++ LYK+ +P +E K E L + G AGV +++P D
Sbjct: 198 -SLKHLYKWAIP---AEGKKNENL-QNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHA 252
Query: 285 -SVVSVLNKEKG--SSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYD 333
+ + + KG A VL++ G G +KGL ++ T +F Y+
Sbjct: 253 RAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 50.8 bits (120), Expect = 2e-06
Identities = 53/219 (24%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 161 TSLYLAASASAEFFADIAL-APMEAAKVRIQTQ---------PGYANTLRDAAPKMYKEE 210
T +A + S AL +P + K+R Q Q + + A+ ++ +EE
Sbjct: 14 TKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEE 73
Query: 211 GLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGY 270
G AF+KG P + I Y ++F FE E +++ V R + V FV G
Sbjct: 74 GPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAR-------EFSVHFVCGG 126
Query: 271 IAGVFCAIVSHPAD------------SVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARI 318
+A + HP D V + L G+ + + G + +KGL +
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGT----MYRSEGPQVFYKGLAPTL 182
Query: 319 IMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESLKKKL 357
I I LQ+ Y S+K ++ P + E+L+ L
Sbjct: 183 IAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLL 221
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 83.2 bits (204), Expect = 3e-16
Identities = 81/236 (34%), Positives = 107/236 (45%), Gaps = 33/236 (13%)
Query: 68 GFGGVLSCGLTHTAVVPLDLVKCRMQVDPQK-------YKGIFNGFSVTLKEDGVRGLAK 120
GFGGV + H PLD VK R+Q P Y G F+ F TL +G+ GL +
Sbjct: 18 GFGGVCLVFVGH----PLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYR 73
Query: 121 GWAPTFLGYS-MQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
G A +G + M +C FGF + K L + +Y L+ A S F I +
Sbjct: 74 GMAAPIIGVTPMFAVCFFGF-GLGKKLQQKHPEDVLSY---PQLFAAGMLSGVFTTGI-M 128
Query: 180 APMEAAKVRIQTQPG-----YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 234
P E K +Q Q Y TL D A K+Y+E G++ YKG MR +P + M F
Sbjct: 129 TPGERIKCLLQIQASSGESKYTGTL-DCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYF 187
Query: 235 ACFERTVEALYKFVVPKPR--SECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVS 288
T E L P+ + SE S P L VAG IAG+F V+ P D + S
Sbjct: 188 ----MTYEWLKNIFTPEGKRVSELSAPRIL----VAGGIAGIFNWAVAIPPDVLKS 235
Score = 56.6 bits (135), Expect = 3e-08
Identities = 48/180 (26%), Positives = 80/180 (44%), Gaps = 8/180 (4%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQ----KYKGIFNGFSVTLKEDGVRGLAKGWAPTF 126
G+LS T + P + +KC +Q+ KY G + +E G+RG+ KG T
Sbjct: 117 GMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTL 176
Query: 127 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 186
+ F YE K +++ G+ + L + +A + F +A+ P + K
Sbjct: 177 MRDVPASGMYFMTYEWLKNIFTPE-GKRVSELSAPRILVAGGIAGIFNWAVAIPP-DVLK 234
Query: 187 VRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEAL 244
R QT P Y N RD ++ ++EG+ + YKG + +R P F FE ++ L
Sbjct: 235 SRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFEVAMKFL 294
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 80.1 bits (196), Expect = 3e-15
Identities = 55/202 (27%), Positives = 96/202 (47%), Gaps = 18/202 (8%)
Query: 50 AVEEYSCE-----FGSAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVD--------P 96
A++ Y E + +Y G ++ +T+ PL + K R+ +
Sbjct: 105 AIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITN----PLWVTKTRLMLQYDAVVNSPH 160
Query: 97 QKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENT 156
++YKG+F+ K +GVRGL KG+ P G S G +F YE+ K+ Y+ +
Sbjct: 161 RQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTS-HGALQFMAYELLKLKYNQHINRLPE 219
Query: 157 YLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFY 216
T Y++ +A ++ FA A P + + R+Q Q + + + D K +++EG+ FY
Sbjct: 220 AQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFY 279
Query: 217 KGVAPLWMRQIPYTMMKFACFE 238
KG+AP +R P + F +E
Sbjct: 280 KGIAPNLIRVTPACCITFVVYE 301
Score = 67.8 bits (164), Expect = 1e-11
Identities = 71/308 (23%), Positives = 125/308 (40%), Gaps = 30/308 (9%)
Query: 47 AAAAVEEYSCEFGSAKYYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVDP-----QKYKG 101
+A+ +S F +Y L GV L++ A+ PLDLVK R V KY G
Sbjct: 7 SASGSSAWSTVFRHVRYENL--IAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNG 64
Query: 102 IFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRT 161
I + + K DG+RGL +G P G + F FY K + E
Sbjct: 65 ILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAER----LEA 120
Query: 162 SLYLAASASAEFFADIALAPMEAAKVRIQTQ-PGYANT-------LRDAAPKMYKEEGLK 213
+ YL ++A A P+ K R+ Q N+ + D K+YK EG++
Sbjct: 121 TEYLVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVR 180
Query: 214 AFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAG 273
YKG P + + ++F +E + + P ++ S E + V ++
Sbjct: 181 GLYKGFVP-GLFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISV----AALSK 235
Query: 274 VFCAIVSHPADSVVSVLNKEKGSSASLV------LKRLGFKGVWKGLFARIIMIGTLTAL 327
+F ++P V + L + + ++ ++ G G +KG+ +I + +
Sbjct: 236 IFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCI 295
Query: 328 QWFIYDSV 335
+ +Y++V
Sbjct: 296 TFVVYENV 303
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 78.2 bits (191), Expect = 1e-14
Identities = 69/279 (24%), Positives = 122/279 (43%), Gaps = 23/279 (8%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
G ++ ++ T+ PLD +K MQV K IF GF +KE G+R L +G +
Sbjct: 201 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIK 260
Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVR 188
+ + KF YE +K L L EE + +++ S + A + PME K R
Sbjct: 261 IAPETAVKFWAYEQYKKL----LTEEGQKIGTFERFISGSMAGAT-AQTFIYPMEVMKTR 315
Query: 189 IQT-QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
+ + G + + D A K+ K EGL AFYKG P + IPY + A +E L K
Sbjct: 316 LAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE-----LLKS 370
Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS-------- 299
++ S ++V G ++ + S+P V + + + S
Sbjct: 371 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 430
Query: 300 --LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
++ + G G+++G+ + + + + +Y+++K
Sbjct: 431 FRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMK 469
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/184 (20%), Positives = 79/184 (42%), Gaps = 16/184 (8%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGY 129
G ++ T + P++++K R+ V +Y GI++ LK +G+ KG+ P LG
Sbjct: 295 GSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGI 354
Query: 130 SMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI 189
YE+ K + + +++ + L A + +A P+ + R+
Sbjct: 355 IPYAGIDLAVYELLKSYWLDNFAKDSVNPG-VMVLLGCGALSSTCGQLASYPLALVRTRM 413
Query: 190 QTQPGYANTLRDAAPKM---------YKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
Q Q + + +P++ +EG+ Y+G+ P +M+ +P + + +E
Sbjct: 414 QAQ-----AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENM 468
Query: 241 VEAL 244
+ L
Sbjct: 469 KQTL 472
Score = 38.1 bits (87), Expect = 0.012
Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR--DAAPKMYKEEGLKAFY 216
WR L A A + + AP++ K+ +Q ++ + +M KE G+++ +
Sbjct: 195 WRQ---LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLW 251
Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
+G ++ P T +KF +E+ YK ++ + + E+ F++G +AG
Sbjct: 252 RGNGTNVIKIAPETAVKFWAYEQ-----YKKLLTEEGQKIGTFER----FISGSMAGATA 302
Query: 277 AIVSHPADSVVSVLNKEKGSS-------ASLVLKRLGFKGVWKGLFARIIMIGTLTALQW 329
+P + + + L K A +LK G +KG ++ I +
Sbjct: 303 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 362
Query: 330 FIYDSVKVYF 339
+Y+ +K Y+
Sbjct: 363 AVYELLKSYW 372
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 78.2 bits (191), Expect = 1e-14
Identities = 69/279 (24%), Positives = 122/279 (43%), Gaps = 23/279 (8%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
G ++ ++ T+ PLD +K MQV K IF GF +KE G+R L +G +
Sbjct: 182 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIK 241
Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVR 188
+ + KF YE +K L L EE + +++ S + A + PME K R
Sbjct: 242 IAPETAVKFWAYEQYKKL----LTEEGQKIGTFERFISGSMAGAT-AQTFIYPMEVMKTR 296
Query: 189 IQT-QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
+ + G + + D A K+ K EGL AFYKG P + IPY + A +E L K
Sbjct: 297 LAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE-----LLKS 351
Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSAS-------- 299
++ S ++V G ++ + S+P V + + + S
Sbjct: 352 YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGL 411
Query: 300 --LVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
++ + G G+++G+ + + + + +Y+++K
Sbjct: 412 FRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMK 450
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/184 (20%), Positives = 79/184 (42%), Gaps = 16/184 (8%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGY 129
G ++ T + P++++K R+ V +Y GI++ LK +G+ KG+ P LG
Sbjct: 276 GSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGI 335
Query: 130 SMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI 189
YE+ K + + +++ + L A + +A P+ + R+
Sbjct: 336 IPYAGIDLAVYELLKSYWLDNFAKDSVNPG-VMVLLGCGALSSTCGQLASYPLALVRTRM 394
Query: 190 QTQPGYANTLRDAAPKM---------YKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERT 240
Q Q + + +P++ +EG+ Y+G+ P +M+ +P + + +E
Sbjct: 395 QAQ-----AMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENM 449
Query: 241 VEAL 244
+ L
Sbjct: 450 KQTL 453
Score = 38.1 bits (87), Expect = 0.012
Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 21/190 (11%)
Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLR--DAAPKMYKEEGLKAFY 216
WR L A A + + AP++ K+ +Q ++ + +M KE G+++ +
Sbjct: 176 WRQ---LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLW 232
Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
+G ++ P T +KF +E+ YK ++ + + E+ F++G +AG
Sbjct: 233 RGNGTNVIKIAPETAVKFWAYEQ-----YKKLLTEEGQKIGTFER----FISGSMAGATA 283
Query: 277 AIVSHPADSVVSVLNKEKGSS-------ASLVLKRLGFKGVWKGLFARIIMIGTLTALQW 329
+P + + + L K A +LK G +KG ++ I +
Sbjct: 284 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343
Query: 330 FIYDSVKVYF 339
+Y+ +K Y+
Sbjct: 344 AVYELLKSYW 353
>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
Length = 301
Score = 76.3 bits (186), Expect = 4e-14
Identities = 69/269 (25%), Positives = 112/269 (41%), Gaps = 27/269 (10%)
Query: 68 GFGGVLSCGLTHTAVVPLDLVKCRMQVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFL 127
G G +C LT P D +K +MQ P YKG+ + F T + G+RG KG P +
Sbjct: 16 GAAGGTACVLTGQ---PFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGTGPALM 72
Query: 128 GYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKV 187
Y + F Y + + G + AA + A FA +AL P E K
Sbjct: 73 AYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELVKC 132
Query: 188 RIQTQ---------PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
R+QT NT+ + K++G FY G++ ++++P F +E
Sbjct: 133 RLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPGYFFFFGGYE 192
Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD------SVVSVLNK 292
+ F + + E V ++G +AG+ +V P D V+S+ K
Sbjct: 193 LSRSF---FASGRSKDELGP----VHLMLSGGVAGICLWLVVFPVDCIKSRIQVLSMYGK 245
Query: 293 EKGSSASL--VLKRLGFKGVWKGLFARII 319
+ G +L V++ G ++ GL A +I
Sbjct: 246 QAGFIGTLLSVVRNEGIVALYSGLKATMI 274
Score = 48.9 bits (115), Expect = 7e-06
Identities = 44/182 (24%), Positives = 70/182 (38%), Gaps = 6/182 (3%)
Query: 160 RTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGV 219
+ ++ L A A+ + P + KV++QT P L D K Y + GL+ FYKG
Sbjct: 8 QAAIDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGT 67
Query: 220 APLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIV 279
P M + + F C+ + + K +++ S + T AG A F A+
Sbjct: 68 GPALMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSD----LQTAAAGSFASAFAALA 123
Query: 280 SHPADSVVSVLNK--EKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
P + V L E S + V KG+ + +G L + V
Sbjct: 124 LCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHGLSSTLLQEVPG 183
Query: 338 YF 339
YF
Sbjct: 184 YF 185
Score = 46.2 bits (108), Expect = 5e-05
Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 22/191 (11%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVD---------PQKYKGIFNGFSVTLKEDGVRGLAKG 121
G + A+ P +LVKCR+Q + + I++ LK+DG G G
Sbjct: 113 GSFASAFAALALCPTELVKCRLQTMYEMEMSGKIAKSHNTIWSVVKGILKKDGPLGFYHG 172
Query: 122 WAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAP 181
+ T L FG YE+ + +++ G L L L+ A + + P
Sbjct: 173 LSSTLLQEVPGYFFFFGGYELSRSFFAS--GRSKDELGPVHLMLSGGV-AGICLWLVVFP 229
Query: 182 MEAAKVRIQT------QPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFA 235
++ K RIQ Q G+ TL + EG+ A Y G+ +R IP F
Sbjct: 230 VDCIKSRIQVLSMYGKQAGFIGTLLSVV----RNEGIVALYSGLKATMIRAIPANGALFV 285
Query: 236 CFERTVEALYK 246
+E + + + K
Sbjct: 286 AYEYSRKMMMK 296
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 75.9 bits (185), Expect = 5e-14
Identities = 82/317 (25%), Positives = 136/317 (42%), Gaps = 41/317 (12%)
Query: 40 PRRPRNLAAAAVEEYSCEFGSAK--YYALCGFGGVLSCGLTHTAVVPLDLVKCRMQVD-- 95
PR PR LAAAA G AK + G L+ G+ P + VK ++Q+D
Sbjct: 4 PRAPRALAAAAPAS-----GKAKLTHPGKAILAGGLAGGIEICITFPTEYVKTQLQLDER 58
Query: 96 --PQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGE 153
P +Y+GI + T++ GV GL +G + G + +FG +E SN + +
Sbjct: 59 SHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFE----FLSNHMRD 114
Query: 154 ENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI---QTQP-----GYANTLRDAAPK 205
L T L + A + + PME KV+ QT P G+ + +R+
Sbjct: 115 AQGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVRE---- 170
Query: 206 MYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVT 265
+ +E+GLK Y+G+ ++Q ++F ++ Y+ P +KP ++T
Sbjct: 171 IVREQGLKGTYQGLTATVLKQGSNQAIRFFVM-TSLRNWYRGDNP------NKPMNPLIT 223
Query: 266 FVAGYIAGVFCAIVSHPADSVVSVLN-------KEKGSSASLVLKRLGFKGVWKGLFARI 318
V G IAG + P D + + + + +LK+ G K +KG R+
Sbjct: 224 GVFGAIAGAASVFGNTPLDVIKTRMQGLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRL 283
Query: 319 IMIGTLTALQWFIYDSV 335
+ A+ + IYD V
Sbjct: 284 GRVCLDVAIVFVIYDEV 300
Score = 59.3 bits (142), Expect = 5e-09
Identities = 52/189 (27%), Positives = 82/189 (43%), Gaps = 16/189 (8%)
Query: 66 LCGFGGVLSCGLTHTAVV--PLDLVKCRM---QVDPQ-KYKGIFNGFSVTLKEDGVRGLA 119
LCG G G+ VV P++ +K + Q P KY+G F+G ++E G++G
Sbjct: 126 LCGLGA----GVAEAVVVVCPMETIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTY 181
Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
+G T L +F + Y + T ++ A + +A F +
Sbjct: 182 QGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGN--- 238
Query: 180 APMEAAKVRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACF 237
P++ K R+Q Y NT D ++ K+EGLKAFYKG P R + F +
Sbjct: 239 TPLDVIKTRMQGLEAHKYRNTW-DCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIY 297
Query: 238 ERTVEALYK 246
+ V+ L K
Sbjct: 298 DEVVKLLNK 306
Score = 39.3 bits (90), Expect = 0.006
Identities = 39/185 (21%), Positives = 79/185 (42%), Gaps = 24/185 (12%)
Query: 181 PMEAAKVRIQ----TQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 236
P E K ++Q + P + D + + G+ Y+G++ L IP ++F
Sbjct: 45 PTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGM 104
Query: 237 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSH-PADSV-VSVLNKEK 294
FE F+ R + + + G AGV A+V P +++ V ++ +
Sbjct: 105 FE--------FLSNHMRDAQGRLDS-TRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQT 155
Query: 295 GSSASL---------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPP 345
+ +++ G KG ++GL A ++ G+ A+++F+ S++ ++R P
Sbjct: 156 SPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPN 215
Query: 346 PPEMP 350
P P
Sbjct: 216 KPMNP 220
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 75.9 bits (185), Expect = 5e-14
Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)
Query: 77 LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
++ T PLD +K MQV + GI GF+ ++E G R L +G L + +
Sbjct: 199 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 258
Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
KF YE K ++G + L R L A + A A ++ PME K R+ +
Sbjct: 259 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 313
Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
G + + D A ++ EG+ AFYKG P + IPY + A +E A L + V
Sbjct: 314 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 370
Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
+ P V ++ G +A A+V + S+ + + +SL +L+
Sbjct: 371 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 428
Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
G G+++GL + + ++ + +Y+++K+
Sbjct: 429 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 75.9 bits (185), Expect = 5e-14
Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)
Query: 77 LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
++ T PLD +K MQV + GI GF+ ++E G R L +G L + +
Sbjct: 233 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 292
Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
KF YE K ++G + L R L A + A A ++ PME K R+ +
Sbjct: 293 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 347
Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
G + + D A ++ EG+ AFYKG P + IPY + A +E A L + V
Sbjct: 348 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 404
Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
+ P V ++ G +A A+V + S+ + + +SL +L+
Sbjct: 405 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 462
Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
G G+++GL + + ++ + +Y+++K+
Sbjct: 463 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 75.9 bits (185), Expect = 5e-14
Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)
Query: 77 LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
++ T PLD +K MQV + GI GF+ ++E G R L +G L + +
Sbjct: 219 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 278
Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
KF YE K ++G + L R L A + A A ++ PME K R+ +
Sbjct: 279 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 333
Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
G + + D A ++ EG+ AFYKG P + IPY + A +E A L + V
Sbjct: 334 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 390
Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
+ P V ++ G +A A+V + S+ + + +SL +L+
Sbjct: 391 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 448
Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
G G+++GL + + ++ + +Y+++K+
Sbjct: 449 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 482
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 75.9 bits (185), Expect = 5e-14
Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)
Query: 77 LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
++ T PLD +K MQV + GI GF+ ++E G R L +G L + +
Sbjct: 199 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 258
Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
KF YE K ++G + L R L A + A A ++ PME K R+ +
Sbjct: 259 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 313
Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
G + + D A ++ EG+ AFYKG P + IPY + A +E A L + V
Sbjct: 314 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 370
Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
+ P V ++ G +A A+V + S+ + + +SL +L+
Sbjct: 371 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 428
Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
G G+++GL + + ++ + +Y+++K+
Sbjct: 429 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 462
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 75.9 bits (185), Expect = 5e-14
Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)
Query: 77 LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
++ T PLD +K MQV + GI GF+ ++E G R L +G L + +
Sbjct: 96 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 155
Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
KF YE K ++G + L R L A + A A ++ PME K R+ +
Sbjct: 156 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 210
Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
G + + D A ++ EG+ AFYKG P + IPY + A +E A L + V
Sbjct: 211 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 267
Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
+ P V ++ G +A A+V + S+ + + +SL +L+
Sbjct: 268 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 325
Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
G G+++GL + + ++ + +Y+++K+
Sbjct: 326 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 359
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 75.9 bits (185), Expect = 5e-14
Identities = 70/274 (25%), Positives = 122/274 (44%), Gaps = 23/274 (8%)
Query: 77 LTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGL 134
++ T PLD +K MQV + GI GF+ ++E G R L +G L + +
Sbjct: 233 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 292
Query: 135 CKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQ-TQP 193
KF YE K ++G + L R L A + A A ++ PME K R+ +
Sbjct: 293 IKFMAYEQIK----RLVGSDQETL-RIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKT 347
Query: 194 GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEA-LYKFVVPKP 252
G + + D A ++ EG+ AFYKG P + IPY + A +E A L + V
Sbjct: 348 GQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV--- 404
Query: 253 RSECSKPEQLV------VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL---VLK 303
+ P V ++ G +A A+V + S+ + + +SL +L+
Sbjct: 405 --NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILR 462
Query: 304 RLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKV 337
G G+++GL + + ++ + +Y+++K+
Sbjct: 463 TEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKI 496
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 75.5 bits (184), Expect = 7e-14
Identities = 67/290 (23%), Positives = 126/290 (43%), Gaps = 36/290 (12%)
Query: 69 FGGVLSCGLTHTAVVPLDLVKCRMQVDPQ---------KYKGIFNGFSVTLKEDGVRGLA 119
+GG+ S + P+DL K R+QV Q KY+G+F+ KE+GV L
Sbjct: 46 YGGLASI-VAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 104
Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
G AP L + G K G Y+ K L+ L E+ T L + + + A+
Sbjct: 105 SGIAPALLRQASYGTIKIGIYQSLKRLFVERL-EDETLLINMICGVVSGVISSTIAN--- 160
Query: 180 APMEAAKVRIQTQPG-YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
P + K+R+Q Q + ++ + +Y++EG + ++GV P R ++ ++
Sbjct: 161 -PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYD 219
Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD----------SVVS 288
T + L + ++ FV+ + G+ A+ S+P D ++V
Sbjct: 220 ITKKHLI--------LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVG 271
Query: 289 VLNKEKGSSASL--VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
++ KG+ + + K GF ++KG + + +G + + Y+ +K
Sbjct: 272 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 321
Score = 55.8 bits (133), Expect = 6e-08
Identities = 45/200 (22%), Positives = 89/200 (44%), Gaps = 30/200 (15%)
Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANT---------LRDAAPKMYKE 209
W+ +Y A A+ P++ K R+Q Q + + A ++ KE
Sbjct: 41 WKPFVY---GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKE 97
Query: 210 EGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAG 269
EG+ A Y G+AP +RQ Y +K ++ +L + V E + E L++ + G
Sbjct: 98 EGVLALYSGIAPALLRQASYGTIKIGIYQ----SLKRLFV-----ERLEDETLLINMICG 148
Query: 270 YIAGVFCAIVSHPADSVVSVLNKEKGS--------SASLVLKRLGFKGVWKGLFARIIMI 321
++GV + +++P D V+ + + +GS S + ++ G +G+W+G+
Sbjct: 149 VVSGVISSTIANPTD-VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 207
Query: 322 GTLTALQWFIYDSVKVYFRL 341
+ ++ +YD K + L
Sbjct: 208 AIVVGVELPVYDITKKHLIL 227
Score = 30.8 bits (68), Expect = 2.0
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 13/86 (15%)
Query: 67 CGFGGVLSCGLTHTAVVPLDLVKCRMQVDP------QKYKGIFNGFSVTLKEDGVRGLAK 120
CG G L+ P+D+V+ RM YKG +G K +G L K
Sbjct: 245 CGLAGALASN-------PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 297
Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVL 146
G+ P +L + F YE K L
Sbjct: 298 GFWPNWLRLGPWNIIFFITYEQLKRL 323
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 75.5 bits (184), Expect = 7e-14
Identities = 67/290 (23%), Positives = 126/290 (43%), Gaps = 36/290 (12%)
Query: 69 FGGVLSCGLTHTAVVPLDLVKCRMQVDPQ---------KYKGIFNGFSVTLKEDGVRGLA 119
+GG+ S + P+DL K R+QV Q KY+G+F+ KE+GV L
Sbjct: 43 YGGLASI-VAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 101
Query: 120 KGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIAL 179
G AP L + G K G Y+ K L+ L E+ T L + + + A+
Sbjct: 102 SGIAPALLRQASYGTIKIGIYQSLKRLFVERL-EDETLLINMICGVVSGVISSTIAN--- 157
Query: 180 APMEAAKVRIQTQPG-YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFE 238
P + K+R+Q Q + ++ + +Y++EG + ++GV P R ++ ++
Sbjct: 158 -PTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYD 216
Query: 239 RTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPAD----------SVVS 288
T + L + ++ FV+ + G+ A+ S+P D ++V
Sbjct: 217 ITKKHLI--------LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVG 268
Query: 289 VLNKEKGSSASL--VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
++ KG+ + + K GF ++KG + + +G + + Y+ +K
Sbjct: 269 HVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLK 318
Score = 55.8 bits (133), Expect = 6e-08
Identities = 45/200 (22%), Positives = 89/200 (44%), Gaps = 30/200 (15%)
Query: 159 WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANT---------LRDAAPKMYKE 209
W+ +Y A A+ P++ K R+Q Q + + A ++ KE
Sbjct: 38 WKPFVY---GGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKE 94
Query: 210 EGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAG 269
EG+ A Y G+AP +RQ Y +K ++ +L + V E + E L++ + G
Sbjct: 95 EGVLALYSGIAPALLRQASYGTIKIGIYQ----SLKRLFV-----ERLEDETLLINMICG 145
Query: 270 YIAGVFCAIVSHPADSVVSVLNKEKGS--------SASLVLKRLGFKGVWKGLFARIIMI 321
++GV + +++P D V+ + + +GS S + ++ G +G+W+G+
Sbjct: 146 VVSGVISSTIANPTD-VLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRA 204
Query: 322 GTLTALQWFIYDSVKVYFRL 341
+ ++ +YD K + L
Sbjct: 205 AIVVGVELPVYDITKKHLIL 224
Score = 30.8 bits (68), Expect = 2.0
Identities = 25/86 (29%), Positives = 34/86 (39%), Gaps = 13/86 (15%)
Query: 67 CGFGGVLSCGLTHTAVVPLDLVKCRMQVDP------QKYKGIFNGFSVTLKEDGVRGLAK 120
CG G L+ P+D+V+ RM YKG +G K +G L K
Sbjct: 242 CGLAGALASN-------PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYK 294
Query: 121 GWAPTFLGYSMQGLCKFGFYEVFKVL 146
G+ P +L + F YE K L
Sbjct: 295 GFWPNWLRLGPWNIIFFITYEQLKRL 320
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 74.7 bits (182), Expect = 1e-13
Identities = 70/314 (22%), Positives = 127/314 (40%), Gaps = 62/314 (19%)
Query: 77 LTHTAVVPLDLVKCRMQVD----------------------------------PQKYKGI 102
LT V PLD+VK R+Q P ++G
Sbjct: 28 LTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKPGNFQGT 87
Query: 103 FNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTS 162
+ F ++ +G++ L G PT + + F Y+ L + LGE T
Sbjct: 88 LDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENET-----C 142
Query: 163 LYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPL 222
+ + A A F A ++P+E + ++Q++ L K E+G + ++G AP
Sbjct: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPT 202
Query: 223 WMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHP 282
+R +P++ M + E L K++ K S +P ++ F +G ++G F A+ + P
Sbjct: 203 VLRDVPFSAM----YWYNYEILKKWLCEK--SGLYEP-TFMINFTSGALSGSFAAVATLP 255
Query: 283 ADSVVS------------VLNKEKGSSASLVLKRL----GFKGVWKGLFARIIMIGTLTA 326
D V + ++ S +++K + GF G++ GL R+I I A
Sbjct: 256 FDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACA 315
Query: 327 LQWFIYDSVKVYFR 340
+ Y+ K +F+
Sbjct: 316 IMISTYEFGKAFFQ 329
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 72.8 bits (177), Expect = 5e-13
Identities = 65/288 (22%), Positives = 113/288 (39%), Gaps = 33/288 (11%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQV---DPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTF 126
G ++ L H+ + P+D VK RMQ DP+ +Y I+ ++ +G +G
Sbjct: 52 GAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVMI 111
Query: 127 LGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAK 186
+G F YE K +++ + + A + A D + P E K
Sbjct: 112 MGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGI---AGSMATLLHDAVMNPAEVVK 168
Query: 187 VRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYK 246
R+Q + +++ EGL AFY+ IP+ + F +E E +
Sbjct: 169 QRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYEFLQEQVNP 228
Query: 247 FVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL------ 300
P+S ++G +AG A + P D ++LN ++ + SL
Sbjct: 229 HRTYNPQSH----------IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR 278
Query: 301 ----------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY 338
V + G G +KG+ AR+I TA+ W +Y+ K +
Sbjct: 279 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYF 326
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 72.0 bits (175), Expect = 8e-13
Identities = 68/279 (24%), Positives = 122/279 (43%), Gaps = 23/279 (8%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
G ++ ++ T PLD +K MQV K I G + E G+R L +G L
Sbjct: 192 GAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLK 251
Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVR 188
+ + KF YE K +LG++ T + + A A A + PME K R
Sbjct: 252 IAPESAIKFMAYEQIK---RAILGQQETLHVQERFVAGSLAGAT--AQTIIYPMEVLKTR 306
Query: 189 IQ-TQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
+ + G L D A ++ + EG +AFY+G P + IPY + A + E L +
Sbjct: 307 LTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVY----ETLKNW 362
Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNK----EKGSSASL--- 300
+ + + + P ++V G I+ I S+P V + + E G S+
Sbjct: 363 WLQQYSHDSADP-GILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGL 421
Query: 301 ---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
+L + G +G+++G+ + + ++ + +Y+++K
Sbjct: 422 LRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMK 460
Score = 55.8 bits (133), Expect = 6e-08
Identities = 41/179 (22%), Positives = 77/179 (43%), Gaps = 6/179 (3%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQ-KYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGY 129
G L+ T + P++++K R+ + +YKG+ + L+ +G R +G+ P LG
Sbjct: 286 GSLAGATAQTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGI 345
Query: 130 SMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRI 189
YE K + ++ L LA + IA P+ + R+
Sbjct: 346 IPYAGIDLAVYETLKNWWLQQYSHDSADPGILVL-LACGTISSTCGQIASYPLALVRTRM 404
Query: 190 QTQP----GYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEAL 244
Q Q G ++ + +EG++ Y+G+AP +M+ IP + + +E +AL
Sbjct: 405 QAQASIEGGPQLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 71.2 bits (173), Expect = 1e-12
Identities = 73/297 (24%), Positives = 125/297 (42%), Gaps = 37/297 (12%)
Query: 69 FGGVLSCGLTHTAVVPLDLVKCRMQVDPQ-----KYKGIFNGFSVTLKEDGVRGLAKGWA 123
FGG+ G T V PLDLVK RMQ+ + +YK F+ + LK +G+RG+ G +
Sbjct: 27 FGGLAGMGAT-VFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGLS 85
Query: 124 PTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENT---YLWRTSLYLAASASAEFF---ADI 177
L + + G Y VL+ + G + T +L + + + A A+ F A++
Sbjct: 86 AGLLRQATYTTTRLGIY---TVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEV 142
Query: 178 ALAPMEA-AKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFAC 236
AL M A ++ + GY N +A ++ +EEG+ ++G P R + + A
Sbjct: 143 ALIRMTADGRLPADQRRGYKNVF-NALIRITREEGVLTLWRGCIPTMARAVVVNAAQLAS 201
Query: 237 FERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGS 296
+ ++ + L + ++ F A I+G+ S P D + + +
Sbjct: 202 YSQSKQFLL--------DSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMI 253
Query: 297 SAS-----------LVLKRLGFKGVWKGLFARIIMIGTLTALQW-FIYDSVKVYFRL 341
V++ GF +WKG +G T L + F+ K Y RL
Sbjct: 254 DGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKAYKRL 310
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 70.9 bits (172), Expect = 2e-12
Identities = 52/204 (25%), Positives = 93/204 (45%), Gaps = 20/204 (9%)
Query: 57 EFGSAKYYALCGFGGVLSCGLTHTAVV-----PLDLVKCRMQVDPQ------KYKGIFNG 105
EF +A G + GLT V P ++VK R+Q +Y G +N
Sbjct: 101 EFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNA 160
Query: 106 FSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLY--SNMLGEENTYLWRTSL 163
+ + +G+ GL KG P + + + Y++ K + +N+L ++
Sbjct: 161 YRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADD------VPC 214
Query: 164 YLAASASAEFFADIALAPMEAAKVR-IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPL 222
+L ++ A F A +P++ K R I + PG ++ + A K++ EG AF+KG+ P
Sbjct: 215 HLVSALIAGFCATAMSSPVDVVKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPS 274
Query: 223 WMRQIPYTMMKFACFERTVEALYK 246
++R + ++ F CFE+ L K
Sbjct: 275 FLRLGSWNVIMFVCFEQLKRELSK 298
Score = 52.8 bits (125), Expect = 5e-07
Identities = 65/289 (22%), Positives = 103/289 (35%), Gaps = 39/289 (13%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQ-------KYKGIFNGFSVTLKEDGVRGLAKGWA 123
G+ +C L PLD K R+QV + +YKG+ + +K +G L G
Sbjct: 21 GIAAC-LADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYSGLP 79
Query: 124 PTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLY--LAASASAEFFADIALAP 181
+ G Y+ + + G+E + + L A F P
Sbjct: 80 AGLQRQISSASLRIGLYDTVQEFLT--AGKETAPSLGSKILAGLTTGGVAVFIGQ----P 133
Query: 182 MEAAKVRIQTQ-------PGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 234
E KVR+Q Q P Y T +A + EGL +KG P MR + +
Sbjct: 134 TEVVKVRLQAQSHLHGIKPRYTGTY-NAYRIIATTEGLTGLWKGTTPNLMRSVIINCTEL 192
Query: 235 ACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSV-VSVLNKE 293
++ EA K + C V+ IAG +S P D V +N
Sbjct: 193 VTYDLMKEAFVKNNILADDVPCH--------LVSALIAGFCATAMSSPVDVVKTRFINSP 244
Query: 294 KGSSASL------VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVK 336
G S+ V G +KGL + +G+ + + ++ +K
Sbjct: 245 PGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLK 293
Score = 34.3 bits (77), Expect = 0.18
Identities = 40/195 (20%), Positives = 67/195 (34%), Gaps = 29/195 (14%)
Query: 165 LAASASAEFFADIALAPMEAAKVRIQTQPGYANT--------LRDAAPKMYKEEGLKAFY 216
L ++ A AD+ P++ AKVR+Q Q G T + + K EG Y
Sbjct: 17 LFSAGIAACLADVITFPLDTAKVRLQVQ-GECPTSSVIRYKGVLGTITAVVKTEGRMKLY 75
Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
G+ RQI ++ ++ E L P L +AG G
Sbjct: 76 SGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAP--------SLGSKILAGLTTGGVA 127
Query: 277 AIVSHPADSVVSVLNKEKG------------SSASLVLKRLGFKGVWKGLFARIIMIGTL 324
+ P + V L + ++ ++ G G+WKG ++ +
Sbjct: 128 VFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVII 187
Query: 325 TALQWFIYDSVKVYF 339
+ YD +K F
Sbjct: 188 NCTELVTYDLMKEAF 202
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 70.1 bits (170), Expect = 3e-12
Identities = 60/205 (29%), Positives = 91/205 (44%), Gaps = 21/205 (10%)
Query: 49 AAVEEYSCEFGSAKYYALCG---------FGGVLSCGLTHTAVVPLDLVKCRMQVDPQK- 98
+A EEY GS YY G F G L+ + PLDLV+ RM V P++
Sbjct: 109 SAHEEYKRILGS--YYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEM 166
Query: 99 YKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYL 158
Y IF+ F +E+G++ L G+ PT LG F YE K L+ G Y
Sbjct: 167 YSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYP 226
Query: 159 WRTSLYLAASA----SAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEG-LK 213
+ ++ A + SA + D+ M+ A V + A TLR + +EEG ++
Sbjct: 227 FERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIARTLR----TIVREEGAVR 282
Query: 214 AFYKGVAPLWMRQIPYTMMKFACFE 238
YKG++ W++ + F F+
Sbjct: 283 GLYKGLSMNWVKGPIAVGISFTTFD 307
Score = 56.6 bits (135), Expect = 3e-08
Identities = 69/286 (24%), Positives = 118/286 (41%), Gaps = 27/286 (9%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVDPQKY--KGIFNGFSVTLKEDGVRGLAKGWAPTFLG 128
G L+ L TAV PLD K QV +++ K F T +G L +G + T +
Sbjct: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVR 99
Query: 129 YSMQGLCKFGFYEVFKVLYSNMLGEENTYL--WRTSLYLAASASAEFFADIALAPMEAAK 186
+F +E +K + + G L W L A A A A P++ +
Sbjct: 100 VVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPR---LFAGALAGTTAASLTYPLDLVR 156
Query: 187 VRIQTQPG--YANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEAL 244
R+ P Y+N ++ +EEGLK Y G P + IPY + F +E T+++L
Sbjct: 157 ARMAVTPKEMYSNIFH-VFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYE-TLKSL 214
Query: 245 YKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSV------VSVLNKEKGSSA 298
++ R + E+++ G AG+ S+P D V V + S A
Sbjct: 215 HREY--SGRRQPYPFERMIF----GACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIA 268
Query: 299 ----SLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFR 340
++V + +G++KGL + + + +D +++ R
Sbjct: 269 RTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIMLR 314
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/282 (25%), Positives = 115/282 (40%), Gaps = 40/282 (14%)
Query: 80 TAVVPLDLVKCRMQ--------VDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM 131
TAV P+DLVK RMQ V YK F+ F L+ +G GL +G P LG +
Sbjct: 344 TAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAP 403
Query: 132 QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFAD----IALAPMEAAKV 187
+ K + + + + G S+ LAA A A I P+E K+
Sbjct: 404 EKAIKLTVNDFVRDKFMHKDG---------SVPLAAEILAGGCAGGSQVIFTNPLEIVKI 454
Query: 188 RIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
R+Q R +A + ++ G YKG ++R IP++ + F C+ A K
Sbjct: 455 RLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY-----AHVKA 509
Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL------- 300
+ S L +AG IAG+ A + PAD + + L + +
Sbjct: 510 SFANEDGQVSPGSLL----LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDC 565
Query: 301 ---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYF 339
+L+ G K +WKG AR+ + Y+ ++ +F
Sbjct: 566 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 607
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 70.1 bits (170), Expect = 3e-12
Identities = 73/282 (25%), Positives = 115/282 (40%), Gaps = 40/282 (14%)
Query: 80 TAVVPLDLVKCRMQ--------VDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM 131
TAV P+DLVK RMQ V YK F+ F L+ +G GL +G P LG +
Sbjct: 345 TAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGLLPQLLGVAP 404
Query: 132 QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFAD----IALAPMEAAKV 187
+ K + + + + G S+ LAA A A I P+E K+
Sbjct: 405 EKAIKLTVNDFVRDKFMHKDG---------SVPLAAEILAGGCAGGSQVIFTNPLEIVKI 455
Query: 188 RIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKF 247
R+Q R +A + ++ G YKG ++R IP++ + F C+ A K
Sbjct: 456 RLQVAGEITTGPRVSALSVVRDLGFFGIYKGAKACFLRDIPFSAIYFPCY-----AHVKA 510
Query: 248 VVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASL------- 300
+ S L +AG IAG+ A + PAD + + L + +
Sbjct: 511 SFANEDGQVSPGSLL----LAGAIAGMPAASLVTPADVIKTRLQVAARAGQTTYSGVIDC 566
Query: 301 ---VLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYF 339
+L+ G K +WKG AR+ + Y+ ++ +F
Sbjct: 567 FRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELLQRWF 608
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 68.9 bits (167), Expect = 7e-12
Identities = 48/185 (25%), Positives = 82/185 (44%), Gaps = 13/185 (7%)
Query: 71 GVLSCGLTHTAVVPLDLVKCRMQVD--------PQKYKGIFNGFSVTLKEDGVRGLAKGW 122
G + + T P D+VK R Q +KY G + + +E+GVRGL KG
Sbjct: 123 GCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGT 182
Query: 123 APTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPM 182
P + ++ + Y++ K L + + + ++ A F A + +P+
Sbjct: 183 LPNIMRNAIVNCAEVVTYDILK----EKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPV 238
Query: 183 EAAKVR-IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTV 241
+ K R + + PG + D KM +EG AFYKG P ++R + ++ F +E+
Sbjct: 239 DVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLK 298
Query: 242 EALYK 246
AL K
Sbjct: 299 RALMK 303
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 34/194 (17%)
Query: 168 SASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMY-----------KEEGLKAFY 216
+ +A FAD+ P++ AKVR+Q Q G ++ A Y + EG + Y
Sbjct: 20 AGTAACFADLVTFPLDTAKVRLQIQ-GENQAVQTARLVQYRGVLGTILTMVRTEGPCSPY 78
Query: 217 KGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFC 276
G+ RQ+ + ++ ++ +V+ +Y PK S L +AG G
Sbjct: 79 NGLVAGLQRQMSFASIRIGLYD-SVKQVY---TPKGADNSS----LTTRILAGCTTGAMA 130
Query: 277 AIVSHPADSV---------VSVLNKEKGSSASL-----VLKRLGFKGVWKGLFARIIMIG 322
+ P D V + ++ S ++ + + G +G+WKG I+
Sbjct: 131 VTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNA 190
Query: 323 TLTALQWFIYDSVK 336
+ + YD +K
Sbjct: 191 IVNCAEVVTYDILK 204
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 67.8 bits (164), Expect = 1e-11
Identities = 78/305 (25%), Positives = 124/305 (40%), Gaps = 33/305 (10%)
Query: 63 YYALCGF--GGVLSCGLTHTAVVPLDLVKCRMQVDPQKYK--GIFNGFSVTLKEDGVRGL 118
+Y L F GG+ C T V PLD VK +Q YK G+F+ +++G GL
Sbjct: 34 FYWLRSFLAGGIAGC-CAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGL 92
Query: 119 AKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIA 178
KG + G +F +E +K L + LG ++ R L A + A A I
Sbjct: 93 YKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISG-HVHR----LMAGSMAGMTAVIC 147
Query: 179 LAPMEAAKVR----IQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKF 234
P++ +VR ++ + Y + KE G FY+G+ P + PY + F
Sbjct: 148 TYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSF 207
Query: 235 ACFERTVEALYKFVVPK--PRSECSKPEQLV----VTFVAGYIAGVFCAIVSHPAD---- 284
F T++++ P R P LV V + G +AG +S+P D
Sbjct: 208 FTF-GTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRR 266
Query: 285 -----SVVSVLNK--EKGSSASLVLKRLGF-KGVWKGLFARIIMIGTLTALQWFIYDSVK 336
+V+ K + V G KG+++GL I A+ + Y+ +K
Sbjct: 267 RMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMK 326
Query: 337 VYFRL 341
+F L
Sbjct: 327 QFFHL 331
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,662,747
Number of Sequences: 37866
Number of extensions: 647513
Number of successful extensions: 2450
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2058
Number of HSP's gapped (non-prelim): 175
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.