Search of human proteins with 4505675

Search of human proteins with 4505675

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]
         (593 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]             1207   0.0  
gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]            1143   0.0  
gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]            1115   0.0  
gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]            1063   0.0  
gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]             970   0.0  
gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]             914   0.0  
gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]             914   0.0  
gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens]             914   0.0  
gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]             885   0.0  
gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]             882   0.0  
gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]             882   0.0  
gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens]             882   0.0  
gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens]             882   0.0  
gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762728 phosphodiesterase 9A isoform g [Homo sapiens]             804   0.0  
gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens]             785   0.0  
gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens]             785   0.0  
gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]            177   2e-44
gi|32306513 phosphodiesterase 4D isoform 2 [Homo sapiens]             177   2e-44
gi|82799486 phosphodiesterase 4B isoform 1 [Homo sapiens]             177   2e-44
gi|82799484 phosphodiesterase 4B isoform 3 [Homo sapiens]             177   2e-44
gi|82799482 phosphodiesterase 4B isoform 2 [Homo sapiens]             177   2e-44
gi|32171241 phosphodiesterase 4B isoform 1 [Homo sapiens]             177   2e-44
gi|162329612 phosphodiesterase 4A isoform 3 [Homo sapiens]            177   3e-44
gi|162329610 phosphodiesterase 4A isoform 2 [Homo sapiens]            177   3e-44
gi|162329608 phosphodiesterase 4A isoform 1 [Homo sapiens]            177   3e-44
gi|5453862 phosphodiesterase 4A isoform 4 [Homo sapiens]              177   3e-44

>gi|4505675 phosphodiesterase 9A isoform a [Homo sapiens]
          Length = 593

 Score = 1207 bits (3123), Expect = 0.0
 Identities = 593/593 (100%), Positives = 593/593 (100%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE 120
           VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE
Sbjct: 61  VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE 120

Query: 121 GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH 180
           GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH
Sbjct: 121 GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH 180

Query: 181 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 240
           LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 181 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 240

Query: 241 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 300
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 241 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 300

Query: 301 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 360
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 301 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 360

Query: 361 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 420
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 361 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 420

Query: 421 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 480
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 421 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 480

Query: 481 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 540
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 481 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 540

Query: 541 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 541 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593


>gi|48762750 phosphodiesterase 9A isoform o [Homo sapiens]
          Length = 567

 Score = 1143 bits (2957), Expect = 0.0
 Identities = 567/593 (95%), Positives = 567/593 (95%), Gaps = 26/593 (4%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR             
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPR------------- 47

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE 120
                        TPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE
Sbjct: 48  -------------TPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE 94

Query: 121 GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH 180
           GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH
Sbjct: 95  GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH 154

Query: 181 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 240
           LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 155 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 214

Query: 241 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 300
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 215 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 274

Query: 301 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 360
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 275 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 334

Query: 361 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 420
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 335 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 394

Query: 421 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 480
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 395 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 454

Query: 481 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 540
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 455 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 514

Query: 541 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 515 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 567


>gi|48762748 phosphodiesterase 9A isoform n [Homo sapiens]
          Length = 552

 Score = 1115 bits (2883), Expect = 0.0
 Identities = 547/547 (100%), Positives = 547/547 (100%)

Query: 47  RNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPL 106
           RNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPL
Sbjct: 6   RNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPL 65

Query: 107 RDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSR 166
           RDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSR
Sbjct: 66  RDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSR 125

Query: 167 AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS 226
           AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS
Sbjct: 126 AFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYS 185

Query: 227 FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR 286
           FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR
Sbjct: 186 FLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVR 245

Query: 287 DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM 346
           DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM
Sbjct: 246 DFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILM 305

Query: 347 TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP 406
           TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP
Sbjct: 306 TAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPP 365

Query: 407 DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE 466
           DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE
Sbjct: 366 DGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNE 425

Query: 467 VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE 526
           VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE
Sbjct: 426 VRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFE 485

Query: 527 TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK 586
           TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK
Sbjct: 486 TVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVK 545

Query: 587 NSEGDCA 593
           NSEGDCA
Sbjct: 546 NSEGDCA 552


>gi|48762746 phosphodiesterase 9A isoform m [Homo sapiens]
          Length = 526

 Score = 1063 bits (2749), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 74  TPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPR 133
           TPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPR
Sbjct: 7   TPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPR 66

Query: 134 EPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL 193
           EPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL
Sbjct: 67  EPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL 126

Query: 194 KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI 253
           KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI
Sbjct: 127 KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETI 186

Query: 254 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN 313
           EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN
Sbjct: 187 EALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHN 246

Query: 314 FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV 373
           FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV
Sbjct: 247 FRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAV 306

Query: 374 RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD 433
           RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD
Sbjct: 307 RYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMD 366

Query: 434 SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS 493
           SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS
Sbjct: 367 SFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKS 426

Query: 494 EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 553
           EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL
Sbjct: 427 EGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEEL 486

Query: 554 KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593
           KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 487 KRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 526


>gi|48762718 phosphodiesterase 9A isoform b [Homo sapiens]
          Length = 533

 Score =  970 bits (2508), Expect = 0.0
 Identities = 498/593 (83%), Positives = 507/593 (85%), Gaps = 60/593 (10%)

Query: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
           MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
Sbjct: 1   MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 61  VSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRRE 120
           VSIDPTMPANSERTPYKVRPVAIKQLS               ER    + V+     +  
Sbjct: 61  VSIDPTMPANSERTPYKVRPVAIKQLS---------------EREELIQSVLAQVAEQFS 105

Query: 121 GAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANH 180
            AF+                            I  + A+VA   +   K  EL+      
Sbjct: 106 RAFK----------------------------INELKAEVANHLAVLEKRVELEG----- 132

Query: 181 LAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 240
           L V+E            IEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV
Sbjct: 133 LKVVE------------IEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDV 180

Query: 241 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 300
           PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF
Sbjct: 181 PTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLF 240

Query: 301 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 360
           CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN
Sbjct: 241 CVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYN 300

Query: 361 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 420
           NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI
Sbjct: 301 NTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLI 360

Query: 421 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 480
           LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL
Sbjct: 361 LATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCL 420

Query: 481 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 540
           LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML
Sbjct: 421 LEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIML 480

Query: 541 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593
           QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 481 QPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 533


>gi|48762732 phosphodiesterase 9A isoform h [Homo sapiens]
          Length = 507

 Score =  914 bits (2363), Expect = 0.0
 Identities = 449/462 (97%), Positives = 450/462 (97%)

Query: 132 PREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 191
           PR P        +   EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE
Sbjct: 46  PRTPYKVRPVAIKQLSEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELE 105

Query: 192 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 251
           GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE
Sbjct: 106 GLKVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPE 165

Query: 252 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 311
           TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF
Sbjct: 166 TIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPF 225

Query: 312 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 371
           HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL
Sbjct: 226 HNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTEL 285

Query: 372 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 431
           AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI
Sbjct: 286 AVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEI 345

Query: 432 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 491
           MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE
Sbjct: 346 MDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDRE 405

Query: 492 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 551
           KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE
Sbjct: 406 KSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYE 465

Query: 552 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 593
           ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 466 ELKRIDDAMKELQKKTDSLTSGATEKSRERSRDVKNSEGDCA 507


>gi|48762726 phosphodiesterase 9A isoform f [Homo sapiens]
          Length = 492

 Score =  914 bits (2362), Expect = 0.0
 Identities = 446/446 (100%), Positives = 446/446 (100%)

Query: 148 EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 207
           EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK
Sbjct: 47  EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 106

Query: 208 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 267
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 107 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 166

Query: 268 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 327
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 167 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 226

Query: 328 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 387
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 227 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 286

Query: 388 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 447
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 287 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 346

Query: 448 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 507
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 347 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 406

Query: 508 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 407 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 466

Query: 568 DSLTSGATEKSRERSRDVKNSEGDCA 593
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 467 DSLTSGATEKSRERSRDVKNSEGDCA 492


>gi|48762720 phosphodiesterase 9A isoform c [Homo sapiens]
          Length = 466

 Score =  914 bits (2362), Expect = 0.0
 Identities = 446/446 (100%), Positives = 446/446 (100%)

Query: 148 EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 207
           EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK
Sbjct: 21  EREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKK 80

Query: 208 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 267
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 81  MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 140

Query: 268 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 327
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 141 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 200

Query: 328 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 387
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 201 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 260

Query: 388 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 447
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 261 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 320

Query: 448 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 507
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 321 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 380

Query: 508 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 381 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 440

Query: 568 DSLTSGATEKSRERSRDVKNSEGDCA 593
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 441 DSLTSGATEKSRERSRDVKNSEGDCA 466


>gi|48762734 phosphodiesterase 9A isoform i [Homo sapiens]
          Length = 433

 Score =  885 bits (2286), Expect = 0.0
 Identities = 429/432 (99%), Positives = 430/432 (99%)

Query: 162 EQFSRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC 221
           + F RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC
Sbjct: 2   DAFRRAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNC 61

Query: 222 PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD 281
           PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD
Sbjct: 62  PCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHD 121

Query: 282 LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD 341
           LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD
Sbjct: 122 LGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTD 181

Query: 342 ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF 401
           ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF
Sbjct: 182 ILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIF 241

Query: 402 SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC 461
           SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC
Sbjct: 242 SNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCC 301

Query: 462 DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL 521
           DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL
Sbjct: 302 DISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVL 361

Query: 522 IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER 581
           IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER
Sbjct: 362 IPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRER 421

Query: 582 SRDVKNSEGDCA 593
           SRDVKNSEGDCA
Sbjct: 422 SRDVKNSEGDCA 433


>gi|48762740 phosphodiesterase 9A isoform l [Homo sapiens]
          Length = 491

 Score =  882 bits (2280), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 166 RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 225
           RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY
Sbjct: 64  RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 123

Query: 226 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 285
           SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV
Sbjct: 124 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 183

Query: 286 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 345
           RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL
Sbjct: 184 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 243

Query: 346 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 405
           MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP
Sbjct: 244 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 303

Query: 406 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 465
           PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN
Sbjct: 304 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 363

Query: 466 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 525
           EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF
Sbjct: 364 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 423

Query: 526 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 585
           ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV
Sbjct: 424 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 483

Query: 586 KNSEGDCA 593
           KNSEGDCA
Sbjct: 484 KNSEGDCA 491



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 23/23 (100%), Positives = 23/23 (100%)

Query: 1  MGSGSSSYRPKAIYLDIDGRIQK 23
          MGSGSSSYRPKAIYLDIDGRIQK
Sbjct: 1  MGSGSSSYRPKAIYLDIDGRIQK 23


>gi|48762738 phosphodiesterase 9A isoform k [Homo sapiens]
          Length = 459

 Score =  882 bits (2280), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 166 RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 225
           RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY
Sbjct: 32  RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 91

Query: 226 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 285
           SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV
Sbjct: 92  SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 151

Query: 286 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 345
           RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL
Sbjct: 152 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 211

Query: 346 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 405
           MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP
Sbjct: 212 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 271

Query: 406 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 465
           PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN
Sbjct: 272 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 331

Query: 466 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 525
           EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF
Sbjct: 332 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 391

Query: 526 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 585
           ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV
Sbjct: 392 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 451

Query: 586 KNSEGDCA 593
           KNSEGDCA
Sbjct: 452 KNSEGDCA 459



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 27/27 (100%), Positives = 27/27 (100%)

Query: 47 RNTTISLLTTDDAMVSIDPTMPANSER 73
          RNTTISLLTTDDAMVSIDPTMPANSER
Sbjct: 6  RNTTISLLTTDDAMVSIDPTMPANSER 32


>gi|48762724 phosphodiesterase 9A isoform e [Homo sapiens]
          Length = 540

 Score =  882 bits (2280), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 166 RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 225
           RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY
Sbjct: 113 RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 172

Query: 226 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 285
           SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV
Sbjct: 173 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 232

Query: 286 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 345
           RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL
Sbjct: 233 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 292

Query: 346 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 405
           MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP
Sbjct: 293 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 352

Query: 406 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 465
           PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN
Sbjct: 353 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 412

Query: 466 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 525
           EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF
Sbjct: 413 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 472

Query: 526 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 585
           ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV
Sbjct: 473 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 532

Query: 586 KNSEGDCA 593
           KNSEGDCA
Sbjct: 533 KNSEGDCA 540



 Score =  148 bits (374), Expect = 1e-35
 Identities = 73/73 (100%), Positives = 73/73 (100%)

Query: 1  MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60
          MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM
Sbjct: 1  MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAM 60

Query: 61 VSIDPTMPANSER 73
          VSIDPTMPANSER
Sbjct: 61 VSIDPTMPANSER 73


>gi|48762722 phosphodiesterase 9A isoform d [Homo sapiens]
          Length = 465

 Score =  882 bits (2280), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 166 RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 225
           RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY
Sbjct: 38  RAFKINELKAEVANHLAVLEKRVELEGLKVVEIEKCKSDIKKMREELAARSSRTNCPCKY 97

Query: 226 SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 285
           SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV
Sbjct: 98  SFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLV 157

Query: 286 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 345
           RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL
Sbjct: 158 RDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILIL 217

Query: 346 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 405
           MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP
Sbjct: 218 MTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIP 277

Query: 406 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 465
           PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN
Sbjct: 278 PDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISN 337

Query: 466 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 525
           EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF
Sbjct: 338 EVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMF 397

Query: 526 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 585
           ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV
Sbjct: 398 ETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKSRERSRDV 457

Query: 586 KNSEGDCA 593
           KNSEGDCA
Sbjct: 458 KNSEGDCA 465



 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 23/23 (100%), Positives = 23/23 (100%)

Query: 1  MGSGSSSYRPKAIYLDIDGRIQK 23
          MGSGSSSYRPKAIYLDIDGRIQK
Sbjct: 1  MGSGSSSYRPKAIYLDIDGRIQK 23


>gi|48762752 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 208 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 267
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 268 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 327
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 328 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 387
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 388 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 447
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 448 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 507
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 508 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 568 DSLTSGATEKSRERSRDVKNSEGDCA 593
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762754 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 208 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 267
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 268 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 327
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 328 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 387
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 388 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 447
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 448 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 507
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 508 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 568 DSLTSGATEKSRERSRDVKNSEGDCA 593
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762742 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 208 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 267
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 268 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 327
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 328 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 387
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 388 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 447
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 448 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 507
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 508 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 568 DSLTSGATEKSRERSRDVKNSEGDCA 593
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762730 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 208 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 267
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 268 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 327
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 328 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 387
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 388 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 447
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 448 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 507
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 508 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 568 DSLTSGATEKSRERSRDVKNSEGDCA 593
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762728 phosphodiesterase 9A isoform g [Homo sapiens]
          Length = 386

 Score =  804 bits (2076), Expect = 0.0
 Identities = 386/386 (100%), Positives = 386/386 (100%)

Query: 208 MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 267
           MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE
Sbjct: 1   MREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWE 60

Query: 268 PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 327
           PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM
Sbjct: 61  PNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSM 120

Query: 328 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 387
           VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA
Sbjct: 121 VWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCA 180

Query: 388 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 447
           VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE
Sbjct: 181 VAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNE 240

Query: 448 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 507
           EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV
Sbjct: 241 EHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKV 300

Query: 508 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 567
           TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT
Sbjct: 301 TKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKT 360

Query: 568 DSLTSGATEKSRERSRDVKNSEGDCA 593
           DSLTSGATEKSRERSRDVKNSEGDCA
Sbjct: 361 DSLTSGATEKSRERSRDVKNSEGDCA 386


>gi|48762744 phosphodiesterase 9A isoform j [Homo sapiens]
          Length = 376

 Score =  785 bits (2026), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 219 TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 278
           TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM
Sbjct: 2   TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 61

Query: 279 YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 338
           YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS
Sbjct: 62  YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 121

Query: 339 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 398
           QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC
Sbjct: 122 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 181

Query: 399 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 458
           NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI
Sbjct: 182 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 241

Query: 459 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 518
           KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK
Sbjct: 242 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 301

Query: 519 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 578
           FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS
Sbjct: 302 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 361

Query: 579 RERSRDVKNSEGDCA 593
           RERSRDVKNSEGDCA
Sbjct: 362 RERSRDVKNSEGDCA 376


>gi|48762736 phosphodiesterase 9A isoform j [Homo sapiens]
          Length = 376

 Score =  785 bits (2026), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 219 TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 278
           TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM
Sbjct: 2   TNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHM 61

Query: 279 YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 338
           YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS
Sbjct: 62  YHDLGLVRDFSINPVTLRRWLFCVHDNYRNNPFHNFRHCFCVAQMMYSMVWLCSLQEKFS 121

Query: 339 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 398
           QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC
Sbjct: 122 QTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPEC 181

Query: 399 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 458
           NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI
Sbjct: 182 NIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILI 241

Query: 459 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 518
           KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK
Sbjct: 242 KCCDISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIK 301

Query: 519 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 578
           FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS
Sbjct: 302 FVLIPMFETVTKLFPMVEEIMLQPLWESRDRYEELKRIDDAMKELQKKTDSLTSGATEKS 361

Query: 579 RERSRDVKNSEGDCA 593
           RERSRDVKNSEGDCA
Sbjct: 362 RERSRDVKNSEGDCA 376


>gi|157277988 phosphodiesterase 4D isoform 1 [Homo sapiens]
          Length = 809

 Score =  177 bits (449), Expect = 2e-44
 Identities = 98/328 (29%), Positives = 176/328 (53%), Gaps = 20/328 (6%)

Query: 244 PKYLLSPETIEALRKPTFDVWLW----------EPNEMLSCLEH-MYHDLGLVRDFSINP 292
           P++ +  E  + L K   DV  W            N  L+ + H ++ +  L++ F I  
Sbjct: 382 PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPV 441

Query: 293 VTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 351
            TL  +L  + D+Y  +  +HN  H   V Q  + ++   +L+  F+  +IL  + A+  
Sbjct: 442 DTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAI 501

Query: 352 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 411
           HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     + 
Sbjct: 502 HDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS 561

Query: 412 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCDI 463
           +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D+
Sbjct: 562 LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL 621

Query: 464 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP 523
           SN  +P+++   W D ++EE+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ P
Sbjct: 622 SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHP 681

Query: 524 MFETVTKLFPMVEEIMLQPLWESRDRYE 551
           ++ET   L     + +L  L ++R+ Y+
Sbjct: 682 LWETWADLVHPDAQDILDTLEDNREWYQ 709


>gi|32306513 phosphodiesterase 4D isoform 2 [Homo sapiens]
          Length = 673

 Score =  177 bits (449), Expect = 2e-44
 Identities = 98/328 (29%), Positives = 176/328 (53%), Gaps = 20/328 (6%)

Query: 244 PKYLLSPETIEALRKPTFDVWLW----------EPNEMLSCLEH-MYHDLGLVRDFSINP 292
           P++ +  E  + L K   DV  W            N  L+ + H ++ +  L++ F I  
Sbjct: 246 PRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMHTIFQERDLLKTFKIPV 305

Query: 293 VTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAIC 351
            TL  +L  + D+Y  +  +HN  H   V Q  + ++   +L+  F+  +IL  + A+  
Sbjct: 306 DTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEAVFTDLEILAAIFASAI 365

Query: 352 HDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQ 411
           HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     + 
Sbjct: 366 HDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQEENCDIFQNLTKKQRQS 425

Query: 412 IRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCDI 463
           +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D+
Sbjct: 426 LRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLQNMVHCADL 485

Query: 464 SNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIP 523
           SN  +P+++   W D ++EE+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ P
Sbjct: 486 SNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNASVEKSQVGFIDYIVHP 545

Query: 524 MFETVTKLFPMVEEIMLQPLWESRDRYE 551
           ++ET   L     + +L  L ++R+ Y+
Sbjct: 546 LWETWADLVHPDAQDILDTLEDNREWYQ 573


>gi|82799486 phosphodiesterase 4B isoform 1 [Homo sapiens]
          Length = 736

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 261 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 318
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 353 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 412

Query: 319 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 378
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 413 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 472

Query: 379 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 438
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 473 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 532

Query: 439 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 490
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 533 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 592

Query: 491 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 550
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 593 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 652

Query: 551 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 590
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 653 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 691


>gi|82799484 phosphodiesterase 4B isoform 3 [Homo sapiens]
          Length = 721

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 261 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 318
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 338 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 397

Query: 319 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 378
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 398 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 457

Query: 379 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 438
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 458 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 517

Query: 439 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 490
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 518 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 577

Query: 491 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 550
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 578 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 637

Query: 551 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 590
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 638 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 676


>gi|82799482 phosphodiesterase 4B isoform 2 [Homo sapiens]
          Length = 564

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 261 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 318
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 181 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 240

Query: 319 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 378
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 241 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 300

Query: 379 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 438
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 301 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 360

Query: 439 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 490
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 361 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 420

Query: 491 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 550
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 421 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 480

Query: 551 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 590
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 481 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 519


>gi|32171241 phosphodiesterase 4B isoform 1 [Homo sapiens]
          Length = 736

 Score =  177 bits (449), Expect = 2e-44
 Identities = 101/341 (29%), Positives = 187/341 (54%), Gaps = 13/341 (3%)

Query: 261 FDVWLWEPNEMLSCLEH-MYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCF 318
           F+V  +  N  L+C+ + ++ +  L++ F I+  T   ++  + D+Y ++  +HN  H  
Sbjct: 353 FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAA 412

Query: 319 CVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDI 378
            VAQ  + ++   +L   F+  +IL  + AA  HD+DHPG +N + IN  +ELA+ YND 
Sbjct: 413 DVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDE 472

Query: 379 SPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEK 438
           S LENHH AV F++L E  C+IF N+     + +R+ +I ++LATDM++H  ++   K  
Sbjct: 473 SVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTM 532

Query: 439 MENFDYSNEEHMTL--------LKMILIKCCDISNEVRPMEVAEPWVDCLLEEYFMQSDR 490
           +E    ++   + L        +   ++ C D+SN  + +E+   W D ++EE+F Q D+
Sbjct: 533 VETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDK 592

Query: 491 EKSEGLPVAPFMDRDKVTKATAQIGFIKFVLIPMFETVTKLFPMVEEIMLQPLWESRDRY 550
           E+  G+ ++P  D+   +   +Q+GFI +++ P++ET   L     + +L  L ++R+ Y
Sbjct: 593 ERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY 652

Query: 551 EELKRIDDAMKELQKKTDSLTSGATEKSR-ERSRDVKNSEG 590
           + +  I  +      + +    G  EK + E + D ++SEG
Sbjct: 653 QSM--IPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEG 691


>gi|162329612 phosphodiesterase 4A isoform 3 [Homo sapiens]
          Length = 825

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 236 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 291
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 292 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 350

Query: 292 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 350
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 351 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 410

Query: 351 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 410
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 411 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 470

Query: 411 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 462
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 471 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 530

Query: 463 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 522
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 531 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 590

Query: 523 PMFETVTKLFPMVEEIMLQPLWESRDRY 550
           P++ET   L     + +L  L ++RD Y
Sbjct: 591 PLWETWADLVHPDAQEILDTLEDNRDWY 618


>gi|162329610 phosphodiesterase 4A isoform 2 [Homo sapiens]
          Length = 860

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 236 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 291
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 327 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 385

Query: 292 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 350
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 386 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 445

Query: 351 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 410
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 446 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 505

Query: 411 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 462
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 506 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 565

Query: 463 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 522
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 566 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 625

Query: 523 PMFETVTKLFPMVEEIMLQPLWESRDRY 550
           P++ET   L     + +L  L ++RD Y
Sbjct: 626 PLWETWADLVHPDAQEILDTLEDNRDWY 653


>gi|162329608 phosphodiesterase 4A isoform 1 [Homo sapiens]
          Length = 886

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 236 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 291
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 353 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 411

Query: 292 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 350
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 412 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 471

Query: 351 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 410
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 472 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 531

Query: 411 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 462
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 532 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 591

Query: 463 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 522
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 592 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 651

Query: 523 PMFETVTKLFPMVEEIMLQPLWESRDRY 550
           P++ET   L     + +L  L ++RD Y
Sbjct: 652 PLWETWADLVHPDAQEILDTLEDNRDWY 679


>gi|5453862 phosphodiesterase 4A isoform 4 [Homo sapiens]
          Length = 647

 Score =  177 bits (448), Expect = 3e-44
 Identities = 101/328 (30%), Positives = 179/328 (54%), Gaps = 14/328 (4%)

Query: 236 PRRDVPTYPKYLLSPETIEALRKPTFDVWL---WEPNEMLSCLEHM-YHDLGLVRDFSIN 291
           PR  V T  + LL+ E +E L K   +++    +     L+C+ +M + +  L++ F I 
Sbjct: 114 PRFGVKTDQEELLAQE-LENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIP 172

Query: 292 PVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAI 350
             T+  ++  + D+Y  +  +HN  H   V Q  + ++   +L   F+  +IL  + AA 
Sbjct: 173 VDTMVTYMLTLEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAA 232

Query: 351 CHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFK 410
            HD+DHPG +N + IN  +ELA+ YND S LENHH AV F++L E  C+IF N+     +
Sbjct: 233 IHDVDHPGVSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQ 292

Query: 411 QIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTL--------LKMILIKCCD 462
            +R+ +I ++LATDM++H  ++   K  +E    ++   + L        +   ++ C D
Sbjct: 293 SLRKMVIDMVLATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCAD 352

Query: 463 ISNEVRPMEVAEPWVDCLLEEYFMQSDREKSEGLPVAPFMDRDKVTKATAQIGFIKFVLI 522
           +SN  +P+E+   W D ++ E+F Q DRE+  G+ ++P  D+   +   +Q+GFI +++ 
Sbjct: 353 LSNPTKPLELYRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVH 412

Query: 523 PMFETVTKLFPMVEEIMLQPLWESRDRY 550
           P++ET   L     + +L  L ++RD Y
Sbjct: 413 PLWETWADLVHPDAQEILDTLEDNRDWY 440


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,281,831
Number of Sequences: 37866
Number of extensions: 995269
Number of successful extensions: 3538
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 3290
Number of HSP's gapped (non-prelim): 206
length of query: 593
length of database: 18,247,518
effective HSP length: 108
effective length of query: 485
effective length of database: 14,157,990
effective search space: 6866625150
effective search space used: 6866625150
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.