Search of human proteins with 4505585

Search of human proteins with 4505585

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505585 platelet-activating factor acetylhydrolase, isoform
Ib, beta subunit [Homo sapiens]
         (229 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505585 platelet-activating factor acetylhydrolase, isoform I...   470   e-133
gi|225543099 platelet-activating factor acetylhydrolase, isoform...   312   1e-85
gi|225543097 platelet-activating factor acetylhydrolase, isoform...   312   1e-85
gi|4505587 platelet-activating factor acetylhydrolase, isoform I...   312   1e-85
gi|22035565 GC-rich sequence DNA-binding factor candidate isofor...    33   0.20 
gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]        29   2.9  
gi|47271475 SPOC domain containing 1 [Homo sapiens]                    28   6.5  
gi|223029412 otoconin 90 [Homo sapiens]                                28   8.5  

>gi|4505585 platelet-activating factor acetylhydrolase, isoform Ib,
           beta subunit [Homo sapiens]
          Length = 229

 Score =  470 bits (1209), Expect = e-133
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR 60
           MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR
Sbjct: 1   MSQGDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWR 60

Query: 61  ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA 120
           ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA
Sbjct: 61  ELFSPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEA 120

Query: 121 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV 180
           IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV
Sbjct: 121 IVQLINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFV 180

Query: 181 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA 229
           HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA
Sbjct: 181 HSDGAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEETPEEKQTTIA 229


>gi|225543099 platelet-activating factor acetylhydrolase, isoform
           Ib, gamma subunit [Homo sapiens]
          Length = 231

 Score =  312 bits (800), Expect = 1e-85
 Identities = 141/216 (65%), Positives = 179/216 (82%)

Query: 4   GDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELF 63
           G+ NPA+ P   +D+QGD RWMS H+RFV D KDKEP+V+F+GDS+VQLM Q EIWRELF
Sbjct: 3   GEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELF 62

Query: 64  SPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQ 123
           SPLHALNFGIGGD T+HVLWRL+NGELE+I+PK++VVWVGTNNH +TAE+V GGI+AIVQ
Sbjct: 63  SPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQ 122

Query: 124 LINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSD 183
           L+N RQPQA+++VLGLLPRG+ PNPLR+KN +VN+L++ +L        LD D GFVHSD
Sbjct: 123 LVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSD 182

Query: 184 GAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEE 219
           G IS HDM+D+LHL+  GY  +C+ LH L+++LL +
Sbjct: 183 GTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQ 218


>gi|225543097 platelet-activating factor acetylhydrolase, isoform
           Ib, gamma subunit [Homo sapiens]
          Length = 231

 Score =  312 bits (800), Expect = 1e-85
 Identities = 141/216 (65%), Positives = 179/216 (82%)

Query: 4   GDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELF 63
           G+ NPA+ P   +D+QGD RWMS H+RFV D KDKEP+V+F+GDS+VQLM Q EIWRELF
Sbjct: 3   GEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELF 62

Query: 64  SPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQ 123
           SPLHALNFGIGGD T+HVLWRL+NGELE+I+PK++VVWVGTNNH +TAE+V GGI+AIVQ
Sbjct: 63  SPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQ 122

Query: 124 LINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSD 183
           L+N RQPQA+++VLGLLPRG+ PNPLR+KN +VN+L++ +L        LD D GFVHSD
Sbjct: 123 LVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSD 182

Query: 184 GAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEE 219
           G IS HDM+D+LHL+  GY  +C+ LH L+++LL +
Sbjct: 183 GTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQ 218


>gi|4505587 platelet-activating factor acetylhydrolase, isoform Ib,
           gamma subunit [Homo sapiens]
          Length = 231

 Score =  312 bits (800), Expect = 1e-85
 Identities = 141/216 (65%), Positives = 179/216 (82%)

Query: 4   GDSNPAAIPHAAEDIQGDDRWMSQHNRFVLDCKDKEPDVLFVGDSMVQLMQQYEIWRELF 63
           G+ NPA+ P   +D+QGD RWMS H+RFV D KDKEP+V+F+GDS+VQLM Q EIWRELF
Sbjct: 3   GEENPASKPTPVQDVQGDGRWMSLHHRFVADSKDKEPEVVFIGDSLVQLMHQCEIWRELF 62

Query: 64  SPLHALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQ 123
           SPLHALNFGIGGD T+HVLWRL+NGELE+I+PK++VVWVGTNNH +TAE+V GGI+AIVQ
Sbjct: 63  SPLHALNFGIGGDGTQHVLWRLENGELEHIRPKIVVVWVGTNNHGHTAEQVTGGIKAIVQ 122

Query: 124 LINTRQPQAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSD 183
           L+N RQPQA+++VLGLLPRG+ PNPLR+KN +VN+L++ +L        LD D GFVHSD
Sbjct: 123 LVNERQPQARVVVLGLLPRGQHPNPLREKNRQVNELVRAALAGHPRAHFLDADPGFVHSD 182

Query: 184 GAISCHDMFDFLHLTGGGYAKICKPLHELIMQLLEE 219
           G IS HDM+D+LHL+  GY  +C+ LH L+++LL +
Sbjct: 183 GTISHHDMYDYLHLSRLGYTPVCRALHSLLLRLLAQ 218


>gi|22035565 GC-rich sequence DNA-binding factor candidate isoform 1
           [Homo sapiens]
          Length = 917

 Score = 33.1 bits (74), Expect = 0.20
 Identities = 44/190 (23%), Positives = 78/190 (41%), Gaps = 29/190 (15%)

Query: 21  DDRWMSQHNRFVLDCKDKEPDVLFVGD--SMVQLMQQYEIWRELFSPLHALNFGIGGDTT 78
           DD +M  + + VL+ K+  P + F     S V+L+  +  W  +FS        I G   
Sbjct: 746 DDVFMPLYPKNVLENKNSGPYLFFQRQFWSSVKLLGNFLQWYGIFSNKTLQELSIDGLLN 805

Query: 79  RHVLWRLKNGEL--ENIKPKVIVV------WVGTNNHENTAEEVAGGIEAIVQLINTRQP 130
           R++L   +N E   ++IK    V+      W      E T  ++      +V L +T   
Sbjct: 806 RYILMAFQNSEYGDDSIKKAQNVINCFPKQWFMNLKGERTISQLENFCRYLVHLADT--- 862

Query: 131 QAKIIVLGLLPRGEKPNPLRQKNAKVNQLLKVSLPKLANVQLLDTDGGFVHSDGAISCHD 190
                   +       + + ++NA+ N  +K  +  LA+V+ LD      H+    S H+
Sbjct: 863 --------IYRNSIGCSDVEKRNAREN--IKQIVKLLASVRALD------HAMSVASDHN 906

Query: 191 MFDFLHLTGG 200
           + +F  L  G
Sbjct: 907 VKEFKSLIEG 916


>gi|157885806 chromosome 12 open reading frame 51 [Homo sapiens]
          Length = 3996

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 16/57 (28%), Positives = 31/57 (54%), Gaps = 1/57 (1%)

Query: 68  ALNFGIGGDTTRHVLWRLKNGELENIKPKVIVVWVGTNNHENTAEEVAGGIEAIVQL 124
           +LNF + GDT     + +++G   N   K +  +  T   + ++E+V+GG+  +V L
Sbjct: 723 SLNFKVEGDTVTFS-FEMRSGREHNTPDKAMWGFACTVRAQESSEDVSGGLPFLVDL 778


>gi|47271475 SPOC domain containing 1 [Homo sapiens]
          Length = 1216

 Score = 28.1 bits (61), Expect = 6.5
 Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 11/47 (23%)

Query: 5   DSNPAAIPHAAEDIQGDDRWMSQHNRFVLD-----CKDKEPDVLFVG 46
           D +P A+P A+ED  G      QH+   LD     CKD EP    +G
Sbjct: 764 DCSPQALPIASEDTTG------QHDHHFLDPNCHICKDWEPSNELLG 804


>gi|223029412 otoconin 90 [Homo sapiens]
          Length = 477

 Score = 27.7 bits (60), Expect = 8.5
 Identities = 13/34 (38%), Positives = 17/34 (50%)

Query: 190 DMFDFLHLTGGGYAKICKPLHELIMQLLEETPEE 223
           D F FLHL  G   ++   L E++  L    PEE
Sbjct: 289 DRFTFLHLGSGDNMQVMPQLGEMLFCLTSRCPEE 322


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,517,035
Number of Sequences: 37866
Number of extensions: 414515
Number of successful extensions: 816
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 811
Number of HSP's gapped (non-prelim): 8
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.