Guide to the Human Genome
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Search of human proteins with 13027640

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13027640 aminoadipate-semialdehyde synthase [Homo sapiens]
         (926 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13027640 aminoadipate-semialdehyde synthase [Homo sapiens]        1855   0.0  
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi...    32   2.7  
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi...    32   2.7  
gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens]        30   8.0  
gi|54292123 lysosomal trafficking regulator [Homo sapiens]             30   8.0  

>gi|13027640 aminoadipate-semialdehyde synthase [Homo sapiens]
          Length = 926

 Score = 1855 bits (4804), Expect = 0.0
 Identities = 926/926 (100%), Positives = 926/926 (100%)

Query: 1   MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQ 60
           MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQ
Sbjct: 1   MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAPKHIKGITNLGYKVLIQ 60

Query: 61  PSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANM 120
           PSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANM
Sbjct: 61  PSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMSRKTYAFFSHTIKAQEANM 120

Query: 121 GLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM 180
           GLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM
Sbjct: 121 GLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMINILHGMGLRLLALGHHTPFM 180

Query: 181 HIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPC 240
           HIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPC
Sbjct: 181 HIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLTFVFTGTGNVSKGAQAIFNELPC 240

Query: 241 EYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIA 300
           EYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIA
Sbjct: 241 EYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTDAVYDPAEYDKHPERYISRFNTDIA 300

Query: 301 PYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTG 360
           PYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTG
Sbjct: 301 PYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKFSPAGVEGCPALPHKLVAICDISADTG 360

Query: 361 GSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLY 420
           GSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLY
Sbjct: 361 GSIEFMTECTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLY 420

Query: 421 PYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTR 480
           PYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTR
Sbjct: 421 PYVEEMILSDATQPLESQNFSPVVRDAVITSNGTLPDKYKYIQTLRESRERAQSLSMGTR 480

Query: 481 RKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKL 540
           RKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKL
Sbjct: 481 RKVLVLGSGYISEPVLEYLSRDGNIEITVGSDMKNQIEQLGKKYNINPVSMDICKQEEKL 540

Query: 541 GFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGE 600
           GFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGE
Sbjct: 541 GFLVAKQDLVISLLPYVLHPLVAKACITNKVNMVTASYITPALKELEKSVEDAGITIIGE 600

Query: 601 LGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMN 660
           LGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMN
Sbjct: 601 LGLDPGLDHMLAMETIDKAKEVGATIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMN 660

Query: 661 VMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTL 720
           VMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTL
Sbjct: 661 VMQSATYLLDGKVVNVAGGISFLDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTL 720

Query: 721 LRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLK 780
           LRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLK
Sbjct: 721 LRGTLRYKGYMKALNGFVKLGLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLK 780

Query: 781 EAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRD 840
           EAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRD
Sbjct: 781 EAVLKKLGGDNTQLEAAEWLGLLGDEQVPQAESILDALSKHLVMKLSYGPEEKDMIVMRD 840

Query: 841 SFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFS 900
           SFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFS
Sbjct: 841 SFGIRHPSGHLEHKTIDLVAYGDINGFSAMAKTVGLPTAMAAKMLLDGEIGAKGLMGPFS 900

Query: 901 KEIYGPILERIKAEGIIYTTQSTIKP 926
           KEIYGPILERIKAEGIIYTTQSTIKP
Sbjct: 901 KEIYGPILERIKAEGIIYTTQSTIKP 926


>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
          Length = 1502

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 7/79 (8%)

Query: 511  SDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHP-LVAKACITN 569
            +D  N  +Q  + +NIN VSM++              DL   L+PY LHP L+  A I +
Sbjct: 1303 TDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPD 1362

Query: 570  KVNMVTASYITPALKELEK 588
            K   +       ALKE+ K
Sbjct: 1363 KTERL------HALKEIVK 1375


>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
          Length = 1501

 Score = 32.0 bits (71), Expect = 2.7
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 7/79 (8%)

Query: 511  SDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHP-LVAKACITN 569
            +D  N  +Q  + +NIN VSM++              DL   L+PY LHP L+  A I +
Sbjct: 1302 TDQDNIQKQFDQDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLEAAKIPD 1361

Query: 570  KVNMVTASYITPALKELEK 588
            K   +       ALKE+ K
Sbjct: 1362 KTERL------HALKEIVK 1374


>gi|19923215 myocyte enhancer factor 2C isoform 1 [Homo sapiens]
          Length = 473

 Score = 30.4 bits (67), Expect = 8.0
 Identities = 19/60 (31%), Positives = 28/60 (46%), Gaps = 2/60 (3%)

Query: 660 NVMQSATYLLDGKVVNVAGGISFLDAVTSM--DFFPGLNLEGYPNRDSTKYAEIYGISSA 717
           +V +    LL+ ++ N     S    V S+     PG  + GYP+  ST Y   Y +SSA
Sbjct: 269 SVSEDVDLLLNQRINNSQSAQSLATPVVSVATPTLPGQGMGGYPSAISTTYGTEYSLSSA 328


>gi|54292123 lysosomal trafficking regulator [Homo sapiens]
          Length = 3801

 Score = 30.4 bits (67), Expect = 8.0
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 4/53 (7%)

Query: 369 CTTIEHPFCMYDADQHIIHDSVEGSGILMCSIDNLPAQLPIEATECFGDMLYP 421
           CT   H  C Y    H +H   + SG+L+ +  N  ++ P E T   GD+ YP
Sbjct: 496 CTRKRHRRCEYS---HFMHHHRDLSGLLVSAFKNQVSKNPFEET-ADGDVYYP 544


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.137    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,740,920
Number of Sequences: 37866
Number of extensions: 1558572
Number of successful extensions: 3121
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 3117
Number of HSP's gapped (non-prelim): 7
length of query: 926
length of database: 18,247,518
effective HSP length: 112
effective length of query: 814
effective length of database: 14,006,526
effective search space: 11401312164
effective search space used: 11401312164
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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