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Search of human proteins with 4504875
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
(262 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 560 e-160
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 363 e-100
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 332 2e-91
gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] 290 7e-79
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 274 6e-74
gi|71834853 prostate specific antigen isoform 3 preproprotein [H... 261 3e-70
gi|71834857 prostate specific antigen isoform 5 preproprotein [H... 249 1e-66
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 222 2e-58
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 222 2e-58
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 222 2e-58
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 219 2e-57
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 216 1e-56
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 216 2e-56
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 214 6e-56
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 211 5e-55
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 211 7e-55
gi|11496281 kallikrein 13 precursor [Homo sapiens] 209 3e-54
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 199 3e-51
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 199 3e-51
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 198 3e-51
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 192 2e-49
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 191 6e-49
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 190 9e-49
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 190 9e-49
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 190 9e-49
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 189 3e-48
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 184 7e-47
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 181 7e-46
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 181 7e-46
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 179 2e-45
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 560 bits (1442), Expect = e-160
Identities = 262/262 (100%), Positives = 262/262 (100%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV
Sbjct: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD
Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
Query: 241 PSVAVRVLSYVKWIEDTIAENS 262
PSVAVRVLSYVKWIEDTIAENS
Sbjct: 241 PSVAVRVLSYVKWIEDTIAENS 262
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 363 bits (931), Expect = e-100
Identities = 172/261 (65%), Positives = 203/261 (77%), Gaps = 1/261 (0%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MW LVL +ALS+G TGA P IQSRIVGGWECE+HSQPWQ A+Y CGG+LVH QWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
LTAAHC+ N Q+WLGRHNLF+ E+T Q V VS SFPHP +NMSLL++ + + DED SHD
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
LMLLRL+EPA ITD VKV+ LPT+EP +G+TC ASGWGSIEPE F P LQCV L +L
Sbjct: 121 LMLLRLSEPA-KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLL 179
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
ND C +A+ +KVT+FMLC G GGKDTC GDSGGPL+C+GVLQG+TSWG PC P K
Sbjct: 180 SNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEK 239
Query: 241 PSVAVRVLSYVKWIEDTIAEN 261
P+V +V+ Y KWI+DTIA N
Sbjct: 240 PAVYTKVVHYRKWIKDTIAAN 260
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 332 bits (851), Expect = 2e-91
Identities = 158/261 (60%), Positives = 191/261 (73%), Gaps = 1/261 (0%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
LTAAHCI + + LGRH+LF E+T Q VS SFPHP ++MSLL+N + +D SHD
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
LMLLRL+EPA+ +TDAVKV++LPT+EP +G+TC ASGWGSIEPE F P LQCVDL ++
Sbjct: 121 LMLLRLSEPAE-LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI 179
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
ND C + H QKVT FMLC G GGK TC GDSGGPL+C+GVLQG+TSWG PC P +
Sbjct: 180 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER 239
Query: 241 PSVAVRVLSYVKWIEDTIAEN 261
PS+ +V+ Y KWI+DTI N
Sbjct: 240 PSLYTKVVHYRKWIKDTIVAN 260
>gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]
Length = 223
Score = 290 bits (743), Expect = 7e-79
Identities = 139/210 (66%), Positives = 163/210 (77%), Gaps = 1/210 (0%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MW LVL +ALS+G TGA P IQSRIVGGWECE+HSQPWQ A+Y CGG+LVH QWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
LTAAHC+ N Q+WLGRHNLF+ E+T Q V VS SFPHP +NMSLL++ + + DED SHD
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
LMLLRL+EPA ITD VKV+ LPT+EP +G+TC ASGWGSIEPE F P LQCV L +L
Sbjct: 121 LMLLRLSEPA-KITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLL 179
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTC 210
ND C +A+ +KVT+FMLC G GGKDTC
Sbjct: 180 SNDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 274 bits (700), Expect = 6e-74
Identities = 138/261 (52%), Positives = 164/261 (62%), Gaps = 44/261 (16%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
LTAAHCI R+ +D SHD
Sbjct: 61 LTAAHCI-------------------------------------------RKPGDDSSHD 77
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
LMLLRL+EPA+ +TDAVKV++LPT+EP +G+TC ASGWGSIEPE F P LQCVDL ++
Sbjct: 78 LMLLRLSEPAE-LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI 136
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
ND C + H QKVT FMLC G GGK TC GDSGGPL+C+GVLQG+TSWG PC P +
Sbjct: 137 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER 196
Query: 241 PSVAVRVLSYVKWIEDTIAEN 261
PS+ +V+ Y KWI+DTI N
Sbjct: 197 PSLYTKVVHYRKWIKDTIVAN 217
>gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo
sapiens]
Length = 238
Score = 261 bits (668), Expect = 3e-70
Identities = 127/210 (60%), Positives = 152/210 (72%), Gaps = 1/210 (0%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
LTAAHCI + + LGRH+LF E+T Q VS SFPHP ++MSLL+N + +D SHD
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
LMLLRL+EPA+ +TDAVKV++LPT+EP +G+TC ASGWGSIEPE F P LQCVDL ++
Sbjct: 121 LMLLRLSEPAE-LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI 179
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTC 210
ND C + H QKVT FMLC G GGK TC
Sbjct: 180 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTC 209
>gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo
sapiens]
Length = 220
Score = 249 bits (637), Expect = 1e-66
Identities = 129/261 (49%), Positives = 152/261 (58%), Gaps = 42/261 (16%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
LTAAHCI + + LGRH+LF E+T Q VS SFPHP ++MSLL+N
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKN------------ 108
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
R P D SIEPE F P LQCVDL ++
Sbjct: 109 ----RFLRPGDD--------------------------SSIEPEEFLTPKKLQCVDLHVI 138
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
ND C + H QKVT FMLC G GGK TC GDSGGPL+C+GVLQG+TSWG PC P +
Sbjct: 139 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER 198
Query: 241 PSVAVRVLSYVKWIEDTIAEN 261
PS+ +V+ Y KWI+DTI N
Sbjct: 199 PSLYTKVVHYRKWIKDTIVAN 219
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 222 bits (566), Expect = 2e-58
Identities = 108/257 (42%), Positives = 158/257 (61%), Gaps = 12/257 (4%)
Query: 5 VLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAA 64
++ LAL+ G G ++RI+ G+EC+ HSQPWQAAL+ + CG L+ +W+LTAA
Sbjct: 6 LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLL 124
HC+ Y + LG+HNL +E Q +ESFPHPGFN SL ++D+ +D+ML+
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114
Query: 125 RLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDE 184
++ P +IT AV+ + L + G++CL SGWGS P L+C ++ I+ + +
Sbjct: 115 KMASPV-SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQK 173
Query: 185 CKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVA 244
C+ A+ +TD M+C EGGKD+C GDSGGPL+C+ LQG+ SWG PC KP V
Sbjct: 174 CENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVY 233
Query: 245 VRVLSYVKWIEDTIAEN 261
+V YV WI++T+ N
Sbjct: 234 TKVCKYVDWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 222 bits (566), Expect = 2e-58
Identities = 108/257 (42%), Positives = 158/257 (61%), Gaps = 12/257 (4%)
Query: 5 VLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAA 64
++ LAL+ G G ++RI+ G+EC+ HSQPWQAAL+ + CG L+ +W+LTAA
Sbjct: 38 LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
Query: 65 HCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLL 124
HC+ Y + LG+HNL +E Q +ESFPHPGFN SL ++D+ +D+ML+
Sbjct: 94 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146
Query: 125 RLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDE 184
++ P +IT AV+ + L + G++CL SGWGS P L+C ++ I+ + +
Sbjct: 147 KMASPV-SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQK 205
Query: 185 CKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVA 244
C+ A+ +TD M+C EGGKD+C GDSGGPL+C+ LQG+ SWG PC KP V
Sbjct: 206 CENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVY 265
Query: 245 VRVLSYVKWIEDTIAEN 261
+V YV WI++T+ N
Sbjct: 266 TKVCKYVDWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 222 bits (566), Expect = 2e-58
Identities = 108/257 (42%), Positives = 158/257 (61%), Gaps = 12/257 (4%)
Query: 5 VLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAA 64
++ LAL+ G G ++RI+ G+EC+ HSQPWQAAL+ + CG L+ +W+LTAA
Sbjct: 6 LILLALATGLVGG----ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLL 124
HC+ Y + LG+HNL +E Q +ESFPHPGFN SL ++D+ +D+ML+
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114
Query: 125 RLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDE 184
++ P +IT AV+ + L + G++CL SGWGS P L+C ++ I+ + +
Sbjct: 115 KMASPV-SITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQK 173
Query: 185 CKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVA 244
C+ A+ +TD M+C EGGKD+C GDSGGPL+C+ LQG+ SWG PC KP V
Sbjct: 174 CENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVY 233
Query: 245 VRVLSYVKWIEDTIAEN 261
+V YV WI++T+ N
Sbjct: 234 TKVCKYVDWIQETMKNN 250
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 219 bits (558), Expect = 2e-57
Identities = 109/257 (42%), Positives = 152/257 (59%), Gaps = 12/257 (4%)
Query: 2 WFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVL 61
W +L L + G A + +++GG EC+ HSQPWQAAL+ CGG+LV WVL
Sbjct: 12 WMFLLLLGGAWAGHSRAQ--EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVL 69
Query: 62 TAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDL 121
TAAHC Y + LG H+L + + Q + V +S PHP +N S +E+H +HDL
Sbjct: 70 TAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDH--------NHDL 121
Query: 122 MLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILP 181
MLL+L + A ++ VK + L + G C SGWG++ +FPD L C ++KI P
Sbjct: 122 MLLQLRDQA-SLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP 180
Query: 182 NDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKP 241
+C+ A+ ++TD M+C G +G DTC GDSGGPL+CDG LQG+TSWG PCG +KP
Sbjct: 181 QKKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKP 239
Query: 242 SVAVRVLSYVKWIEDTI 258
V + Y+ WI+ I
Sbjct: 240 GVYTNICRYLDWIKKII 256
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 216 bits (551), Expect = 1e-56
Identities = 104/237 (43%), Positives = 145/237 (61%), Gaps = 10/237 (4%)
Query: 22 QSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLF 81
+ +++GG EC+ HSQPWQAAL+ CGG+LV WVLTAAHC Y + LG H+L
Sbjct: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
Query: 82 DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVE 141
+ + Q + V +S PHP +N S +E+H +HDLMLL+L + A ++ VK +
Sbjct: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDH--------NHDLMLLQLRDQA-SLGSKVKPIS 185
Query: 142 LPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVG 201
L + G C SGWG++ +FPD L C ++KI P +C+ A+ ++TD M+C G
Sbjct: 186 LADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG 245
Query: 202 HLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258
+G DTC GDSGGPL+CDG LQG+TSWG PCG +KP V + Y+ WI+ I
Sbjct: 246 SSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 216 bits (549), Expect = 2e-56
Identities = 111/257 (43%), Positives = 154/257 (59%), Gaps = 16/257 (6%)
Query: 8 LALSLGGTGAAPPIQS--RIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAH 65
L L+ G A P +IVGG+ CE++S P+Q +L S F CGG L+ QWV++AAH
Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAH 63
Query: 66 CISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLR 125
C Q+ LG HN+ E QF++ ++ HP +N L+N D+ML++
Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIK 112
Query: 126 LTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185
L+ PA I V + LPT P G+ CL SGWG+ +PD+L+C+D +L EC
Sbjct: 113 LSSPA-VINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAEC 171
Query: 186 KKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAV 245
K ++ K+T+ M CVG LEGGKD+C DSGGP++C+G LQGV SWG+ C N+P V
Sbjct: 172 KASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYT 230
Query: 246 RVLSYVKWIEDTIAENS 262
+V +YV WI+DTIA NS
Sbjct: 231 KVYNYVDWIKDTIAANS 247
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 214 bits (545), Expect = 6e-56
Identities = 110/250 (44%), Positives = 152/250 (60%), Gaps = 15/250 (6%)
Query: 14 GTGAAP-PIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQ 72
GT A P +IVGG+ CE++S P+Q +L S F CGG L+ QWV++AAHC Q
Sbjct: 69 GTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQ 127
Query: 73 LWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADT 132
+ LG HN+ E QF++ ++ HP +N L+N D+ML++L+ PA
Sbjct: 128 VRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIKLSSPA-V 175
Query: 133 ITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQK 192
I V + LPT P G+ CL SGWG+ +PD+L+C+D +L ECK ++ K
Sbjct: 176 INARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGK 235
Query: 193 VTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVK 252
+T+ M CVG LEGGKD+C DSGGP++C+G LQGV SWG+ C N+P V +V +YV
Sbjct: 236 ITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVD 294
Query: 253 WIEDTIAENS 262
WI+DTIA NS
Sbjct: 295 WIKDTIAANS 304
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 211 bits (537), Expect = 5e-55
Identities = 109/262 (41%), Positives = 153/262 (58%), Gaps = 22/262 (8%)
Query: 6 LCLALSLGGTGAAPPIQS--RIVGGWECEQHSQPWQAAL---YHFSTFQCGGILVHRQWV 60
L L L+ A P +IVGG+ CE++S P+Q +L YHF CGG L+ QWV
Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF----CGGSLISEQWV 58
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
++A HC Q+ LG HN+ E QF++ ++ HP +N L+N D
Sbjct: 59 VSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDN-----------D 107
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
++L++L+ PA I V + LPT P G+ L SGWG+ +PD+LQC+D +L
Sbjct: 108 ILLIKLSSPA-VINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVL 166
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
EC+ ++ K+T+ M CVG LEGGKD+C GDSGGP++ +G LQG+ SWGY C N+
Sbjct: 167 SQAECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWGY-GCAQKNR 225
Query: 241 PSVAVRVLSYVKWIEDTIAENS 262
P V +V +YV WI+DTIA NS
Sbjct: 226 PGVYTKVYNYVDWIKDTIAANS 247
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 211 bits (536), Expect = 7e-55
Identities = 109/260 (41%), Positives = 152/260 (58%), Gaps = 22/260 (8%)
Query: 8 LALSLGGTGAAPPIQS--RIVGGWECEQHSQPWQAAL---YHFSTFQCGGILVHRQWVLT 62
L L+ A P +IVGG+ CE++S P+Q +L YHF CGG L++ QWV++
Sbjct: 5 LILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHF----CGGSLINEQWVVS 60
Query: 63 AAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLM 122
A HC Q+ LG HN+ E QF++ ++ HP ++ L N D+M
Sbjct: 61 AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNN-----------DIM 109
Query: 123 LLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPN 182
L++L+ A I V + LPT P G+ CL SGWG+ +PD+LQC+D +L
Sbjct: 110 LIKLSSRA-VINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQ 168
Query: 183 DECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPS 242
+C+ ++ K+T M CVG LEGGKD+C GDSGGP++C+G LQGV SWG C NKP
Sbjct: 169 AKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPG 227
Query: 243 VAVRVLSYVKWIEDTIAENS 262
V +V +YVKWI++TIA NS
Sbjct: 228 VYTKVYNYVKWIKNTIAANS 247
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 209 bits (531), Expect = 3e-54
Identities = 109/270 (40%), Positives = 153/270 (56%), Gaps = 20/270 (7%)
Query: 1 MWFLVLCLA-LSLGGTGAAPPIQSRIV----------GGWECEQHSQPWQAALYHFSTFQ 49
MW L L +A L+L +G S+++ GG+ C HSQPWQAAL
Sbjct: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60
Query: 50 CGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENH 109
CGG+LVH +WVLTAAHC+ + +++LG+H L E Q V S PHP + S
Sbjct: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRS----- 115
Query: 110 TRQADEDYSHDLMLLRLTEPADTITDAVKVVELP-TEEPEVGSTCLASGWGSIEPENFSF 168
++ HD+MLL L P +T ++ + L G+TC SGWG+ ++
Sbjct: 116 --PTHLNHDHDIMLLELQSPVQ-LTGYIQTLPLSHNNRLTPGTTCRVSGWGTTTSPQVNY 172
Query: 169 PDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVT 228
P LQC ++++ ++EC++ + K+TD MLC G EGGKD+C GDSGGPL+C+ L G+
Sbjct: 173 PKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYGIV 232
Query: 229 SWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258
SWG PCG P++P V RV YV WI +TI
Sbjct: 233 SWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 199 bits (505), Expect = 3e-51
Identities = 104/258 (40%), Positives = 146/258 (56%), Gaps = 17/258 (6%)
Query: 4 LVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTA 63
L+L LAL G A +I+ G C + S PWQ AL + CGG+LV+ +WVLTA
Sbjct: 12 LLLSLALETAGEEAQG---DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
Query: 64 AHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLML 123
AHC + Y + LG L D AQ + S+SF HPG++ + + +DLML
Sbjct: 69 AHCKMNEYTVHLGSDTLGD--RRAQRIKASKSFRHPGYST-----------QTHVNDLML 115
Query: 124 LRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPND 183
++L A ++ VK V LP+ G+TC SGWG+ + +FP DL CVD+K++
Sbjct: 116 VKLNSQA-RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQ 174
Query: 184 ECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSV 243
+C K + + + MLC G + K+ C GDSGGPL+C G LQG+ SWG PCG PN P V
Sbjct: 175 DCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGV 234
Query: 244 AVRVLSYVKWIEDTIAEN 261
+V + KWI DT+ ++
Sbjct: 235 YTQVCKFTKWINDTMKKH 252
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 199 bits (505), Expect = 3e-51
Identities = 104/258 (40%), Positives = 146/258 (56%), Gaps = 17/258 (6%)
Query: 4 LVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTA 63
L+L LAL G A +I+ G C + S PWQ AL + CGG+LV+ +WVLTA
Sbjct: 12 LLLSLALETAGEEAQG---DKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTA 68
Query: 64 AHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLML 123
AHC + Y + LG L D AQ + S+SF HPG++ + + +DLML
Sbjct: 69 AHCKMNEYTVHLGSDTLGD--RRAQRIKASKSFRHPGYST-----------QTHVNDLML 115
Query: 124 LRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPND 183
++L A ++ VK V LP+ G+TC SGWG+ + +FP DL CVD+K++
Sbjct: 116 VKLNSQA-RLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQ 174
Query: 184 ECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSV 243
+C K + + + MLC G + K+ C GDSGGPL+C G LQG+ SWG PCG PN P V
Sbjct: 175 DCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGV 234
Query: 244 AVRVLSYVKWIEDTIAEN 261
+V + KWI DT+ ++
Sbjct: 235 YTQVCKFTKWINDTMKKH 252
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 198 bits (504), Expect = 3e-51
Identities = 108/258 (41%), Positives = 146/258 (56%), Gaps = 13/258 (5%)
Query: 5 VLCLALSL-GGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTA 63
+LC LSL G G A +R +G EC +SQPWQA L+H + CG L+ +W+LTA
Sbjct: 5 LLCALLSLLAGHGWA---DTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTA 61
Query: 64 AHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLML 123
AHC + LG H+L+ E Q V++ FPHPGFN L N D++ D+ML
Sbjct: 62 AHCRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSAN-------DHNDDIML 114
Query: 124 LRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPND 183
+RL A ++ AV+ + L G CL SGWG++ FP LQC ++ IL N
Sbjct: 115 IRLPRQA-RLSPAVQPLNLSQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENK 173
Query: 184 ECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSV 243
C A+ ++D MLC G EGG+ +C GDSGGPL+C+G L GV S G PC P +P+V
Sbjct: 174 LCHWAYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAV 233
Query: 244 AVRVLSYVKWIEDTIAEN 261
V Y+ WI++ I EN
Sbjct: 234 YTSVCHYLDWIQE-IMEN 250
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 192 bits (489), Expect = 2e-49
Identities = 105/271 (38%), Positives = 143/271 (52%), Gaps = 25/271 (9%)
Query: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
MW L+L L+ L T A +++ G EC HSQPWQ ALY F CG L+ WV
Sbjct: 1 MW-LLLTLSFLLASTAAQDG--DKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57
Query: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
L+AAHC S ++ LG HNL + Q S PHP R + +D
Sbjct: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHP-----------RYEARSHRND 106
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSI---EP-------ENFSFPD 170
+MLLRL +PA + V+ LPT P G C+ SGWG + EP S PD
Sbjct: 107 IMLLRLVQPA-RLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPD 165
Query: 171 DLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSW 230
L C ++ I+ + C K++ ++T+ M+C G G ++C GDSGGPL+C G+LQG+ SW
Sbjct: 166 TLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSW 225
Query: 231 GYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 261
G VPC KP V +V Y++WI +T+ N
Sbjct: 226 GDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 191 bits (485), Expect = 6e-49
Identities = 101/241 (41%), Positives = 139/241 (57%), Gaps = 14/241 (5%)
Query: 22 QSRIVGGWECEQHSQPWQAALYHFST--FQCGGILVHRQWVLTAAHCISDNYQLWLGRHN 79
+++I+GG C + SQPWQAAL F CGG L+ QWV+TAAHC Q+ LG+HN
Sbjct: 38 ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHN 97
Query: 80 LFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKV 139
L E T Q + V HP +N +N DLMLL+L +PA I AV+
Sbjct: 98 LRRWEATQQVLRVVRQVTHPNYNSRTHDN-----------DLMLLQLQQPA-RIGRAVRP 145
Query: 140 VELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLC 199
+E+ G++C SGWG+I +P LQCV++ I P++ C+KA+ + +T M+C
Sbjct: 146 IEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVC 205
Query: 200 VGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIA 259
G +GGKD+C GDSGGPL+C G LQG+ SWG C P P V + Y WIE+T+
Sbjct: 206 AGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265
Query: 260 E 260
+
Sbjct: 266 D 266
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 190 bits (483), Expect = 9e-49
Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 15/257 (5%)
Query: 8 LALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALY-HFSTFQCGGILVHRQWVLTAAHC 66
L G + SRI+ G +C+ H+QPWQAAL + CG +LVH QW+LTAAHC
Sbjct: 50 LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC 109
Query: 67 ISDNYQLWLGRHNLFDD-ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLR 125
+++ LG ++L E+ Q +S PHPG++ +S+DLML++
Sbjct: 110 RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIK 158
Query: 126 LTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185
L D V+ + + + P G+ CL SGWG+ + FP LQC+++ +L C
Sbjct: 159 LNRRIRPTKD-VRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRC 217
Query: 186 KKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAV 245
+ A+ +++ D M C G + G+D+C GDSGGP++C+G LQG+ SWG PC PN+P V
Sbjct: 218 EDAYPRQIDDTMFCAGD-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYT 276
Query: 246 RVLSYVKWIEDTIAENS 262
+ + KWI++TI NS
Sbjct: 277 NLCKFTKWIQETIQANS 293
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 190 bits (483), Expect = 9e-49
Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 15/257 (5%)
Query: 8 LALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALY-HFSTFQCGGILVHRQWVLTAAHC 66
L G + SRI+ G +C+ H+QPWQAAL + CG +LVH QW+LTAAHC
Sbjct: 50 LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC 109
Query: 67 ISDNYQLWLGRHNLFDD-ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLR 125
+++ LG ++L E+ Q +S PHPG++ +S+DLML++
Sbjct: 110 RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIK 158
Query: 126 LTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185
L D V+ + + + P G+ CL SGWG+ + FP LQC+++ +L C
Sbjct: 159 LNRRIRPTKD-VRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRC 217
Query: 186 KKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAV 245
+ A+ +++ D M C G + G+D+C GDSGGP++C+G LQG+ SWG PC PN+P V
Sbjct: 218 EDAYPRQIDDTMFCAGD-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYT 276
Query: 246 RVLSYVKWIEDTIAENS 262
+ + KWI++TI NS
Sbjct: 277 NLCKFTKWIQETIQANS 293
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 190 bits (483), Expect = 9e-49
Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 15/257 (5%)
Query: 8 LALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALY-HFSTFQCGGILVHRQWVLTAAHC 66
L G + SRI+ G +C+ H+QPWQAAL + CG +LVH QW+LTAAHC
Sbjct: 50 LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC 109
Query: 67 ISDNYQLWLGRHNLFDD-ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLR 125
+++ LG ++L E+ Q +S PHPG++ +S+DLML++
Sbjct: 110 RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIK 158
Query: 126 LTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185
L D V+ + + + P G+ CL SGWG+ + FP LQC+++ +L C
Sbjct: 159 LNRRIRPTKD-VRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRC 217
Query: 186 KKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAV 245
+ A+ +++ D M C G + G+D+C GDSGGP++C+G LQG+ SWG PC PN+P V
Sbjct: 218 EDAYPRQIDDTMFCAGD-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYT 276
Query: 246 RVLSYVKWIEDTIAENS 262
+ + KWI++TI NS
Sbjct: 277 NLCKFTKWIQETIQANS 293
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 189 bits (479), Expect = 3e-48
Identities = 105/260 (40%), Positives = 143/260 (55%), Gaps = 18/260 (6%)
Query: 3 FLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLT 62
FL+LC+ LG + AA P +I G EC ++SQPWQ L+ ++ +CGG+L+ +WVLT
Sbjct: 6 FLLLCV---LGLSQAATP---KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLT 59
Query: 63 AAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLM 122
AAHC Y + LG H+L + T Q H S HPG+ A + HDL
Sbjct: 60 AAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY---------LGASTSHEHDLR 110
Query: 123 LLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPN 182
LLRL P +T +V+ + LP + G+ C SGWG FPD LQC++L I+ +
Sbjct: 111 LLRLRLPV-RVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSH 169
Query: 183 DECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYV-PCGTPNKP 241
C + ++T M+C G + G+D C GDSGGPL+C GVLQG+ SWG V PCG P
Sbjct: 170 ATCHGVYPGRITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIP 228
Query: 242 SVAVRVLSYVKWIEDTIAEN 261
V + YV WI + N
Sbjct: 229 GVYTYICKYVDWIRMIMRNN 248
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 184 bits (467), Expect = 7e-47
Identities = 101/258 (39%), Positives = 143/258 (55%), Gaps = 17/258 (6%)
Query: 2 WFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVL 61
WFL L L + G+ + S+I+ G +C HSQPWQAAL + C G+LVH QWVL
Sbjct: 10 WFLGY-LILGVAGSLVSGSC-SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVL 67
Query: 62 TAAHCISDNYQLWLGRHNL-FDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
+AAHC ++Y + LG H+L D E +Q V S S HP +N LL N D
Sbjct: 68 SAAHCFQNSYTIGLGLHSLEADQEPGSQMVEASLSVRHPEYNRPLLAN-----------D 116
Query: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
LML++L E +D ++ + + ++ P G++CL SGWG + N P LQCV++ ++
Sbjct: 117 LMLIKLDESVSE-SDTIRSISIASQCPTAGNSCLVSGWGLLA--NGRMPTVLQCVNVSVV 173
Query: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
+ C K + M C G KD+C GDSGGPL+C+G LQG+ S+G PCG
Sbjct: 174 SEEVCSKLYDPLYHPSMFCAGGGHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGV 233
Query: 241 PSVAVRVLSYVKWIEDTI 258
P V + + +WIE T+
Sbjct: 234 PGVYTNLCKFTEWIEKTV 251
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 181 bits (458), Expect = 7e-46
Identities = 90/237 (37%), Positives = 138/237 (58%), Gaps = 14/237 (5%)
Query: 22 QSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLF 81
Q+++V G C++ S P+QAALY CGG+L+H WVLTAAHC N Q++LG+HNL
Sbjct: 19 QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78
Query: 82 DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVE 141
E++ + V + HP ++ + + D+MLLRL PA +++ ++ +
Sbjct: 79 QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAK-LSELIQPLP 126
Query: 142 LPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVG 201
L + ++C GWG + + FPD +QC + ++ +EC+ A+ ++T MLC G
Sbjct: 127 LERDCSANTTSCHILGWG--KTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAG 184
Query: 202 HLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258
+ GKD+C GDSGGPL+C L+G+ SWG +PCG+ KP V V Y WI+ TI
Sbjct: 185 DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 181 bits (458), Expect = 7e-46
Identities = 90/237 (37%), Positives = 138/237 (58%), Gaps = 14/237 (5%)
Query: 22 QSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLF 81
Q+++V G C++ S P+QAALY CGG+L+H WVLTAAHC N Q++LG+HNL
Sbjct: 19 QNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLR 78
Query: 82 DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVE 141
E++ + V + HP ++ + + D+MLLRL PA +++ ++ +
Sbjct: 79 QRESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAK-LSELIQPLP 126
Query: 142 LPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVG 201
L + ++C GWG + + FPD +QC + ++ +EC+ A+ ++T MLC G
Sbjct: 127 LERDCSANTTSCHILGWG--KTADGDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAG 184
Query: 202 HLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258
+ GKD+C GDSGGPL+C L+G+ SWG +PCG+ KP V V Y WI+ TI
Sbjct: 185 DEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 241
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 179 bits (454), Expect = 2e-45
Identities = 100/242 (41%), Positives = 136/242 (56%), Gaps = 18/242 (7%)
Query: 3 FLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLT 62
FL+LC+ LG + AA P +I G EC ++SQPWQ L+ ++ +CGG+L+ +WVLT
Sbjct: 6 FLLLCV---LGLSQAATP---KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLT 59
Query: 63 AAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLM 122
AAHC Y + LG H+L + T Q H S HPG+ A + HDL
Sbjct: 60 AAHCSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY---------LGASTSHEHDLR 110
Query: 123 LLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPN 182
LLRL P +T +V+ + LP + G+ C SGWG FPD LQC++L I+ +
Sbjct: 111 LLRLRLPV-RVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSH 169
Query: 183 DECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYV-PCGTPNKP 241
C + ++T M+C G + G+D C GDSGGPL+C GVLQG+ SWG V PCG P
Sbjct: 170 ATCHGVYPGRITSNMVCAGGVP-GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIP 228
Query: 242 SV 243
V
Sbjct: 229 GV 230
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,849,374
Number of Sequences: 37866
Number of extensions: 558026
Number of successful extensions: 1592
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1011
Number of HSP's gapped (non-prelim): 213
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.