Guide to the Human Genome
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Search of human proteins with 4504437

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504437 heme oxygenase (decyclizing) 1 [Homo sapiens]
         (288 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504437 heme oxygenase (decyclizing) 1 [Homo sapiens]              572   e-163
gi|187761311 heme oxygenase (decyclizing) 2 [Homo sapiens]            255   3e-68
gi|187761309 heme oxygenase (decyclizing) 2 [Homo sapiens]            255   3e-68
gi|187761307 heme oxygenase (decyclizing) 2 [Homo sapiens]            255   3e-68
gi|8051608 heme oxygenase (decyclizing) 2 [Homo sapiens]              255   3e-68
gi|239582763 ral guanine nucleotide dissociation stimulator-like...    30   3.2  
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    29   4.2  
gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre...    29   4.2  
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre...    29   4.2  
gi|239748061 PREDICTED: hypothetical protein XP_002346523 [Homo ...    29   5.5  
gi|239741954 PREDICTED: hypothetical protein XP_002342361 [Homo ...    29   5.5  
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          28   7.2  

>gi|4504437 heme oxygenase (decyclizing) 1 [Homo sapiens]
          Length = 288

 Score =  572 bits (1475), Expect = e-163
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA 60
           MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA
Sbjct: 1   MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVA 60

Query: 61  LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE 120
           LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE
Sbjct: 61  LEEEIERNKESPVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHE 120

Query: 121 VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ 180
           VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ
Sbjct: 121 VGRTEPELLVAHAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQ 180

Query: 181 LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA 240
           LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA
Sbjct: 181 LYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSRAPGLRQRA 240

Query: 241 SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM 288
           SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM
Sbjct: 241 SNKVQDSAPVETPRGKPPLNTRSQAPLLRWVLTLSFLVATVAVGLYAM 288


>gi|187761311 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score =  255 bits (652), Expect = 3e-68
 Identities = 117/208 (56%), Positives = 160/208 (76%)

Query: 12  DLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKES 71
           DLSE LKE TKE H +AEN +F+++F KG + ++ FKL   +LY  Y ALEEE+ERNK+ 
Sbjct: 32  DLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDH 91

Query: 72  PVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVA 131
           P FAP+YFP ELHRK AL +D+ +++G  W+E +    A Q+YV+R+H +G+ EPELLVA
Sbjct: 92  PAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVA 151

Query: 132 HAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEM 191
           HAYTRY+GDLSGGQVLKK+AQ+AL LPS+GEG  F+ F N+ +A +FKQLYR+RMN+L++
Sbjct: 152 HAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDL 211

Query: 192 TPAVRQRVIEEAKTAFLLNIQLFEELQE 219
               ++R++EEA  AF  N+Q+F EL +
Sbjct: 212 NMKTKERIVEEANKAFEYNMQIFNELDQ 239


>gi|187761309 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score =  255 bits (652), Expect = 3e-68
 Identities = 117/208 (56%), Positives = 160/208 (76%)

Query: 12  DLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKES 71
           DLSE LKE TKE H +AEN +F+++F KG + ++ FKL   +LY  Y ALEEE+ERNK+ 
Sbjct: 32  DLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDH 91

Query: 72  PVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVA 131
           P FAP+YFP ELHRK AL +D+ +++G  W+E +    A Q+YV+R+H +G+ EPELLVA
Sbjct: 92  PAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVA 151

Query: 132 HAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEM 191
           HAYTRY+GDLSGGQVLKK+AQ+AL LPS+GEG  F+ F N+ +A +FKQLYR+RMN+L++
Sbjct: 152 HAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDL 211

Query: 192 TPAVRQRVIEEAKTAFLLNIQLFEELQE 219
               ++R++EEA  AF  N+Q+F EL +
Sbjct: 212 NMKTKERIVEEANKAFEYNMQIFNELDQ 239


>gi|187761307 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score =  255 bits (652), Expect = 3e-68
 Identities = 117/208 (56%), Positives = 160/208 (76%)

Query: 12  DLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKES 71
           DLSE LKE TKE H +AEN +F+++F KG + ++ FKL   +LY  Y ALEEE+ERNK+ 
Sbjct: 32  DLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDH 91

Query: 72  PVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVA 131
           P FAP+YFP ELHRK AL +D+ +++G  W+E +    A Q+YV+R+H +G+ EPELLVA
Sbjct: 92  PAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVA 151

Query: 132 HAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEM 191
           HAYTRY+GDLSGGQVLKK+AQ+AL LPS+GEG  F+ F N+ +A +FKQLYR+RMN+L++
Sbjct: 152 HAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDL 211

Query: 192 TPAVRQRVIEEAKTAFLLNIQLFEELQE 219
               ++R++EEA  AF  N+Q+F EL +
Sbjct: 212 NMKTKERIVEEANKAFEYNMQIFNELDQ 239


>gi|8051608 heme oxygenase (decyclizing) 2 [Homo sapiens]
          Length = 316

 Score =  255 bits (652), Expect = 3e-68
 Identities = 117/208 (56%), Positives = 160/208 (76%)

Query: 12  DLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLVMASLYHIYVALEEEIERNKES 71
           DLSE LKE TKE H +AEN +F+++F KG + ++ FKL   +LY  Y ALEEE+ERNK+ 
Sbjct: 32  DLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMERNKDH 91

Query: 72  PVFAPVYFPEELHRKAALEQDLAFWYGPRWQEVIPYTPAMQRYVKRLHEVGRTEPELLVA 131
           P FAP+YFP ELHRK AL +D+ +++G  W+E +    A Q+YV+R+H +G+ EPELLVA
Sbjct: 92  PAFAPLYFPMELHRKEALTKDMEYFFGENWEEQVQCPKAAQKYVERIHYIGQNEPELLVA 151

Query: 132 HAYTRYLGDLSGGQVLKKIAQKALDLPSSGEGLAFFTFPNIASATKFKQLYRSRMNSLEM 191
           HAYTRY+GDLSGGQVLKK+AQ+AL LPS+GEG  F+ F N+ +A +FKQLYR+RMN+L++
Sbjct: 152 HAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFENVDNAQQFKQLYRARMNALDL 211

Query: 192 TPAVRQRVIEEAKTAFLLNIQLFEELQE 219
               ++R++EEA  AF  N+Q+F EL +
Sbjct: 212 NMKTKERIVEEANKAFEYNMQIFNELDQ 239


>gi|239582763 ral guanine nucleotide dissociation stimulator-like 3
           isoform 2 [Homo sapiens]
          Length = 710

 Score = 29.6 bits (65), Expect = 3.2
 Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 7/70 (10%)

Query: 211 IQLFEELQELLTHDTKDQSPSRAPGLRQRASNKVQDSAPVETPR------GKPPLNTRSQ 264
           I L + L   L  + K  SPS +PG     ++ V   +P  +PR      G PP +   Q
Sbjct: 519 ISLTKRLSAKLARE-KSSSPSGSPGDPSSPTSSVSPGSPPSSPRSRDAPAGSPPASPGPQ 577

Query: 265 APLLRWVLTL 274
            P  +  L+L
Sbjct: 578 GPSTKLPLSL 587


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)

Query: 226 KDQSPSRAPGLRQ----RASNKVQDSAPVETPRGKPPLNTRSQAP 266
           K Q P   PG  Q    +  NK Q   P   P+G PP   +S++P
Sbjct: 46  KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 90


>gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3
           preproprotein [Homo sapiens]
          Length = 178

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)

Query: 226 KDQSPSRAPGLRQ----RASNKVQDSAPVETPRGKPPLNTRSQAP 266
           K Q P   PG  Q    +  NK Q   P   P+G PP   +S++P
Sbjct: 46  KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 90


>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
           preproprotein [Homo sapiens]
          Length = 198

 Score = 29.3 bits (64), Expect = 4.2
 Identities = 16/45 (35%), Positives = 21/45 (46%), Gaps = 4/45 (8%)

Query: 226 KDQSPSRAPGLRQ----RASNKVQDSAPVETPRGKPPLNTRSQAP 266
           K Q P   PG  Q    +  NK Q   P   P+G PP   +S++P
Sbjct: 46  KPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 90


>gi|239748061 PREDICTED: hypothetical protein XP_002346523 [Homo
           sapiens]
          Length = 182

 Score = 28.9 bits (63), Expect = 5.5
 Identities = 14/32 (43%), Positives = 19/32 (59%), Gaps = 1/32 (3%)

Query: 235 GLRQRASNKVQDSAPVETPRGKPPLNTRSQAP 266
           GLR     K   SAP  T RG+PPL+ +++ P
Sbjct: 76  GLRHEIRLK-SGSAPASTARGRPPLSPQAETP 106


>gi|239741954 PREDICTED: hypothetical protein XP_002342361 [Homo
           sapiens]
          Length = 152

 Score = 28.9 bits (63), Expect = 5.5
 Identities = 14/32 (43%), Positives = 19/32 (59%), Gaps = 1/32 (3%)

Query: 235 GLRQRASNKVQDSAPVETPRGKPPLNTRSQAP 266
           GLR     K   SAP  T RG+PPL+ +++ P
Sbjct: 46  GLRHEIRLK-SGSAPASTARGRPPLSPQAETP 76


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 28.5 bits (62), Expect = 7.2
 Identities = 26/96 (27%), Positives = 38/96 (39%), Gaps = 4/96 (4%)

Query: 173  ASATKFKQLYRSRMNSLEMTPAVRQRVIEEAKTAFLLNIQLFEELQELLTHDTKDQSPSR 232
            A  +  KQ       +   TP VR         +  L+ + +E+L E+ +  +  QS   
Sbjct: 937  AKLSPMKQAQLRNFLAKRKTPPVRSTAPASLSRSAFLSQRYYEDLDEVSSTSSVSQSLES 996

Query: 233  APGLRQRASNKVQDSAPVETPRGKPPLNTRSQAPLL 268
                  R S K  D A V+ PR  P + T S  P L
Sbjct: 997  EDA---RTSCK-DDEAVVQAPRHAPVVRTPSIQPSL 1028


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,062,509
Number of Sequences: 37866
Number of extensions: 499345
Number of successful extensions: 1602
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1590
Number of HSP's gapped (non-prelim): 17
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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