Search of human proteins with 4504201

Search of human proteins with 4504201

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504201 general transcription factor IIH, polypeptide 4,
52kDa [Homo sapiens]
         (462 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504201 general transcription factor IIH, polypeptide 4, 52kD...   918   0.0  
gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]              32   1.2  
gi|4505777 PHD finger protein 1 isoform a [Homo sapiens]               31   2.1  
gi|13435397 PHD finger protein 1 isoform b [Homo sapiens]              31   2.1  
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ...    30   3.5  
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform...    30   3.5  
gi|222352127 sidekick 2 [Homo sapiens]                                 29   7.9  
gi|194097442 protein tyrosine phosphatase, receptor type, N poly...    29   7.9  
gi|194097440 protein tyrosine phosphatase, receptor type, N poly...    29   7.9  
gi|194097438 protein tyrosine phosphatase, receptor type, N poly...    29   7.9  
gi|119220554 serine palmitoyltransferase, long chain base subuni...    29   7.9  

>gi|4504201 general transcription factor IIH, polypeptide 4, 52kDa
           [Homo sapiens]
          Length = 462

 Score =  918 bits (2373), Expect = 0.0
 Identities = 462/462 (100%), Positives = 462/462 (100%)

Query: 1   MESTPSRGLNRVHLQCRNLQEFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRML 60
           MESTPSRGLNRVHLQCRNLQEFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRML
Sbjct: 1   MESTPSRGLNRVHLQCRNLQEFLGGLSPGVLDRLYGHPATCLAVFRELPSLAKNWVMRML 60

Query: 61  FLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRI 120
           FLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRI
Sbjct: 61  FLEQPLPQAAVALWVKKEFSKAQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRI 120

Query: 121 ALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLS 180
           ALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLS
Sbjct: 121 ALLGGGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLS 180

Query: 181 QAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQL 240
           QAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQL
Sbjct: 181 QAGLMKSTEPGEPPCITSAGFQFLLLDTPAQLWYFMLQYLQTAQSRGMDLVEILSFLFQL 240

Query: 241 SFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGT 300
           SFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGT
Sbjct: 241 SFSTLGKDYSVEGMSDSLLNFLQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGT 300

Query: 301 VHQPGFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGIT 360
           VHQPGFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGIT
Sbjct: 301 VHQPGFIVVETNYRLYAYTESELQIALIALFSEMLYRFPNMVVAQVTRESVQQAIASGIT 360

Query: 361 AQQIIHFLRTRAHPVMLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFEL 420
           AQQIIHFLRTRAHPVMLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFEL
Sbjct: 361 AQQIIHFLRTRAHPVMLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFEL 420

Query: 421 LLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS 462
           LLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS
Sbjct: 421 LLAHARELGVLVFENSAKRLMVVTPAGHSDVKRFWKRQKHSS 462


>gi|116006951 polycystin 1-like 2 isoform a [Homo sapiens]
          Length = 2459

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 17/55 (30%), Positives = 25/55 (45%)

Query: 379  QTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVF 433
            QT ++P    D++  W L    LRF EGV Y   + + D E        +G+  F
Sbjct: 1224 QTHLVPMVAPDELPTWILSPQDLRFGEGVYYLTVVPESDLEPAPGRDLTVGITTF 1278


>gi|4505777 PHD finger protein 1 isoform a [Homo sapiens]
          Length = 457

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 9/65 (13%)

Query: 385 PTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFENSAKRLMV-- 442
           PT   + RLWE +    R+T+G+LY   + +VD       ARE+ ++ FE+ ++ L++  
Sbjct: 23  PTSGPRPRLWEGQDVLARWTDGLLYLGTIKKVD------SAREVCLVQFEDDSQFLVLWK 76

Query: 443 -VTPA 446
            ++PA
Sbjct: 77  DISPA 81


>gi|13435397 PHD finger protein 1 isoform b [Homo sapiens]
          Length = 567

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 21/65 (32%), Positives = 38/65 (58%), Gaps = 9/65 (13%)

Query: 385 PTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFENSAKRLMV-- 442
           PT   + RLWE +    R+T+G+LY   + +VD       ARE+ ++ FE+ ++ L++  
Sbjct: 23  PTSGPRPRLWEGQDVLARWTDGLLYLGTIKKVD------SAREVCLVQFEDDSQFLVLWK 76

Query: 443 -VTPA 446
            ++PA
Sbjct: 77  DISPA 81


>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
           [Homo sapiens]
          Length = 621

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 125 GGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLSQAGL 184
           G K WS+D  QL      + V         RWEV+ ++M    S+ V +    ++ +A  
Sbjct: 450 GSKNWSEDDLQL----LIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKS 505

Query: 185 MKSTEPGEPPCITSAGF 201
           ++  +P +   I    F
Sbjct: 506 LQKLDPHQKDDINKKAF 522


>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
           [Homo sapiens]
          Length = 568

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 19/77 (24%), Positives = 33/77 (42%), Gaps = 4/77 (5%)

Query: 125 GGKAWSDDTSQLGPDKHARDVPSLDKYAEERWEVVLHFMVGSPSAAVSQDLAQLLSQAGL 184
           G K WS+D  QL      + V         RWEV+ ++M    S+ V +    ++ +A  
Sbjct: 397 GSKNWSEDDLQL----LIKAVNLFPAGTNSRWEVIANYMNIHSSSGVKRTAKDVIGKAKS 452

Query: 185 MKSTEPGEPPCITSAGF 201
           ++  +P +   I    F
Sbjct: 453 LQKLDPHQKDDINKKAF 469


>gi|222352127 sidekick 2 [Homo sapiens]
          Length = 2172

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 11/70 (15%)

Query: 82   AQEESTGLLSGLRIWHTQLLPGGLQGLILNPIFRQNLRIALLGGGKAWSDDTSQLGPDKH 141
            A+++  G+L G RI + +LL  GL+G  L  I            G  W++ TS       
Sbjct: 1526 AEDKINGILLGFRIRYRELLYEGLRGFTLRGINNP---------GATWAELTSMYSMRNL 1576

Query: 142  ARDVPSLDKY 151
            +R  PSL +Y
Sbjct: 1577 SR--PSLTQY 1584


>gi|194097442 protein tyrosine phosphatase, receptor type, N
           polypeptide 2 isoform 3 precursor [Homo sapiens]
          Length = 986

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 3/40 (7%)

Query: 110 LNPIFRQNLRIALL---GGGKAWSDDTSQLGPDKHARDVP 146
           ++P+  Q LR+AL    G G  W DD +Q   D+   D+P
Sbjct: 74  VSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLP 113


>gi|194097440 protein tyrosine phosphatase, receptor type, N
           polypeptide 2 isoform 1 precursor [Homo sapiens]
          Length = 1015

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 3/40 (7%)

Query: 110 LNPIFRQNLRIALL---GGGKAWSDDTSQLGPDKHARDVP 146
           ++P+  Q LR+AL    G G  W DD +Q   D+   D+P
Sbjct: 74  VSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLP 113


>gi|194097438 protein tyrosine phosphatase, receptor type, N
           polypeptide 2 isoform 2 precursor [Homo sapiens]
          Length = 998

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 3/40 (7%)

Query: 110 LNPIFRQNLRIALL---GGGKAWSDDTSQLGPDKHARDVP 146
           ++P+  Q LR+AL    G G  W DD +Q   D+   D+P
Sbjct: 57  VSPVALQRLRVALQKLSGTGFTWQDDYTQYVMDQELADLP 96


>gi|119220554 serine palmitoyltransferase, long chain base subunit 3
           [Homo sapiens]
          Length = 552

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 35/180 (19%), Positives = 73/180 (40%), Gaps = 10/180 (5%)

Query: 262 LQHLREFGLVFQRKRKSRRYYPTRLAINLSSGVSGAGGTVHQPGFIVVETNYRLYAYTES 321
           L+ L    +++ + R  R +   ++ I +    S  G  VH P  I ++  Y+ Y Y + 
Sbjct: 280 LEKLLRDAVIYGQPRTRRAW--KKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDE 337

Query: 322 ELQIALIALFSEMLYRF----PNMVVAQVTRESVQQAIASGITA--QQIIHFLRTRAHPV 375
              I  +      +  F    P+ V   +   +     + G  A  + ++ +LR  +H  
Sbjct: 338 AHSIGAVGPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSA 397

Query: 376 MLKQTPVLPPTITDQIRLWELERDRLRFTEGVLYNQFLSQVDFELLLAHARELGVLVFEN 435
           +   + + PP     IR  +L       T+G+   Q L++ +        +E+G +++ N
Sbjct: 398 VYASS-MSPPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAK-NTRYFRQRLQEMGFIIYGN 455


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,612,113
Number of Sequences: 37866
Number of extensions: 773050
Number of successful extensions: 1590
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1588
Number of HSP's gapped (non-prelim): 11
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.