Search of human proteins with 4503947

Search of human proteins with 4503947

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503947 glucagon receptor [Homo sapiens]
         (477 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503947 glucagon receptor [Homo sapiens]                           994   0.0  
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     435   e-122
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          415   e-116
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   353   2e-97
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   286   4e-77
gi|114205383 secretin receptor precursor [Homo sapiens]               285   6e-77
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   247   1e-65
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   244   1e-64
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    240   2e-63
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    234   1e-61
gi|58530851 growth hormone releasing hormone receptor isoform a ...   231   1e-60
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   196   5e-50
gi|5031621 calcitonin receptor-like [Homo sapiens]                    187   1e-47
gi|4502547 calcitonin receptor [Homo sapiens]                         186   4e-47
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   182   8e-46
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   181   1e-45
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   176   4e-44
gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   166   4e-41
gi|58530853 growth hormone releasing hormone receptor isoform b ...   160   2e-39
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]              92   1e-18
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]            70   5e-12
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]            70   5e-12
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]            70   5e-12
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo...    67   4e-11
gi|240120161 G protein-coupled receptor 144 [Homo sapiens]             64   3e-10
gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo s...    64   3e-10
gi|163792198 latrophilin 3 precursor [Homo sapiens]                    64   3e-10
gi|40807489 egf-like module containing, mucin-like, hormone rece...    64   4e-10
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           59   7e-09
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           59   7e-09

>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  994 bits (2569), Expect = 0.0
 Identities = 477/477 (100%), Positives = 477/477 (100%)

Query: 1   MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR 60
           MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
Sbjct: 1   MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR 60

Query: 61  TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ 120
           TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
Sbjct: 61  TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ 120

Query: 121 CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL 180
           CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
Sbjct: 121 CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL 180

Query: 181 FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC 240
           FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
Sbjct: 181 FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC 240

Query: 241 WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN 300
           WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
Sbjct: 241 WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN 300

Query: 301 MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV 360
           MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
Sbjct: 301 MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV 360

Query: 361 HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL 420
           HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
Sbjct: 361 HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL 420

Query: 421 GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF 477
           GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
Sbjct: 421 GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF 477


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  435 bits (1118), Expect = e-122
 Identities = 231/458 (50%), Positives = 292/458 (63%), Gaps = 19/458 (4%)

Query: 10  LLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWP 69
           L L  LLL         Q    L+++W+ Y  +C   L+   PP+ L CN +FD Y CW 
Sbjct: 13  LSLCGLLLQRAETGSKGQTAGELYQRWERYRRECQETLAAAEPPSGLACNGSFDMYVCWD 72

Query: 70  DTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMDGEEIE 129
               N TA  SCPWYLPWHH V   FV ++CG DGQW        WRD +QC+ + E+ E
Sbjct: 73  YAAPNATARASCPWYLPWHHHVAAGFVLRQCGSDGQWGL------WRDHTQCE-NPEKNE 125

Query: 130 VQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKAS 189
              +   +    QVMYTVGYSLSL  LLLAL IL    +LHCTRN IH NLF SF+L+A+
Sbjct: 126 AFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFRRLHCTRNYIHINLFTSFMLRAA 185

Query: 190 SVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYL 249
           ++L  D LL  R    +GD  +++ W  + A+A CR A +  QY + ANY WLLVEG+YL
Sbjct: 186 AILSRDRLL-PRPGPYLGDQ-ALALW--NQALAACRTAQIVTQYCVGANYTWLLVEGVYL 241

Query: 250 HNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRF 309
           H+LL L    E   F  YL +GWGAP LFV+PW +V+ L+EN QCW  N+    WWI+R 
Sbjct: 242 HSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYENTQCWERNEVKAIWWIIRT 301

Query: 310 PVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVT 369
           P+ + ILINF IF+RI+ +L++KLR RQM   DY+ RLA+STLTL+PLLGVHEVVFA VT
Sbjct: 302 PILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARSTLTLVPLLGVHEVVFAPVT 361

Query: 370 DEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERN 429
           +E A+G LR AKL F++FLSSFQG LV+VLYCF+NKEVQSE+RR WH  RL + L EE+ 
Sbjct: 362 EEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQSEIRRGWHHCRLRRSLGEEQR 421

Query: 430 TSNHRA------SSSPGHGPPSKELQFGR--GGGSQDS 459
               RA       S PG  P S+ L  G   G G++ S
Sbjct: 422 QLPERAFRALPSGSGPGEVPTSRGLSSGTLPGPGNEAS 459


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  415 bits (1066), Expect = e-116
 Identities = 214/426 (50%), Positives = 279/426 (65%), Gaps = 24/426 (5%)

Query: 9   PLLLLLLLLAC------QPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPP-TELVCNRT 61
           PL L LLLL        +PQ  +  + + + +KW+ Y  QC  +L+  PPP T+L CNRT
Sbjct: 7   PLRLALLLLGMVGRAGPRPQGATVSLWETV-QKWREYRRQCQRSLTEDPPPATDLFCNRT 65

Query: 62  FDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQ-PWRDASQ 120
           FD+Y+CWPD    +  N+SCPWYLPW   V    V++ C  +G W++      PWRD S+
Sbjct: 66  FDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSE 125

Query: 121 CQMD--GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHA 178
           C+    GE    ++++  +Y    ++YTVGY+LS  AL++A AIL G   LHCTRN IH 
Sbjct: 126 CEESKRGERSSPEEQLLFLY----IIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHL 181

Query: 179 NLFASFVLKASSVLVIDGLLRTRYS----QKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234
           NLFASF+L+A SV + D  L+  YS    Q   D L     LS      CR+  + MQY 
Sbjct: 182 NLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGL-----LSYQDSLSCRLVFLLMQYC 236

Query: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294
           + ANY WLLVEG+YL+ LL  + L E+  F LY+ IGWG P+LFVVPW +VK L+E+  C
Sbjct: 237 VAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGC 296

Query: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTL 354
           WT N NM +W I+R P+  AI +NF IFVR++ ++V+KL+A  M  TD K RLAKSTLTL
Sbjct: 297 WTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTL 356

Query: 355 IPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRR 414
           IPLLG HEV+FAFV DEHA+GTLR  KLF +L  +SFQGL+VA+LYCF+N EVQ E R+ 
Sbjct: 357 IPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKS 416

Query: 415 WHRWRL 420
           W RWRL
Sbjct: 417 WERWRL 422


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  353 bits (906), Expect = 2e-97
 Identities = 186/419 (44%), Positives = 259/419 (61%), Gaps = 10/419 (2%)

Query: 6   PQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKY 65
           P RP L L+LL++ +    S  +++    KW  Y   C  +L  L  P+ + CN TFD+Y
Sbjct: 48  PGRPFLTLVLLVSIKQVTGS--LLEETTRKWAQYKQACLRDL--LKEPSGIFCNGTFDQY 103

Query: 66  SCWP-DTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQP-WRDASQCQM 123
            CWP  +P N +  + CP YLPW  +      ++ C   G W         W+D S+C  
Sbjct: 104 VCWPHSSPGNVS--VPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECS- 160

Query: 124 DGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFAS 183
           +    +   +   + S+ Q+MYTVGYS SL +L LAL +L  L KLHCTRN IH NLFAS
Sbjct: 161 ENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFAS 220

Query: 184 FVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLL 243
           F+L+  +VLV D +    YS++  ++    ++LS+ + + CR   V + Y + ANY WLL
Sbjct: 221 FILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTS-CRSVQVLLHYFVGANYLWLL 279

Query: 244 VEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGF 303
           VEGLYLH LL    LPER  +  YL +GW  P+LFVVPW   +   EN  CWT+N N   
Sbjct: 280 VEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKI 339

Query: 304 WWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEV 363
           WWI+R P+ L + +NFFIF++I++LL++KL+A QM   DYK+RLAKSTL LIPLLGVHE+
Sbjct: 340 WWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEI 399

Query: 364 VFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGK 422
           +F+F+TD+  +G  +  +LF  L LSSF G LVA+ Y F N EV++ELR+ W R+ L +
Sbjct: 400 LFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLAR 458


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  286 bits (731), Expect = 4e-77
 Identities = 154/369 (41%), Positives = 216/369 (58%), Gaps = 21/369 (5%)

Query: 58  CNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRD 117
           C++ +D  +CWP TP      ++CP        +Q R V + C  +G W     G P+  
Sbjct: 63  CSKMWDNLTCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEG-WTHLEPG-PYPI 120

Query: 118 ASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIH 177
           A  C +D +   + ++    Y S +  YT+GY LSL  LL+A AIL    KLHCTRN IH
Sbjct: 121 A--CGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIH 178

Query: 178 ANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVA 237
            +LF SF+L+A++V + D  L          D   S   S+G+V GC+ A VF QY ++A
Sbjct: 179 MHLFISFILRAAAVFIKDLALF---------DSGESDQCSEGSV-GCKAAMVFFQYCVMA 228

Query: 238 NYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTS 297
           N+ WLLVEGLYL+ LL ++   ER +F  Y+ IGWG P  F + W + +  FE+  CW  
Sbjct: 229 NFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCW-D 287

Query: 298 NDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYK--FRLAKSTLTLI 355
             N   WWI++ P+  +IL+NF +F+ I+++L+ KLR   +  +D     RLA+STL LI
Sbjct: 288 TINSSLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLI 347

Query: 356 PLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRW 415
           PL GVH ++FAF  D          K+ F+L + SFQG +VA+LYCFLN EVQ+ELRR+W
Sbjct: 348 PLFGVHYIMFAFFPDNFKP----EVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKW 403

Query: 416 HRWRLGKVL 424
            RW L  VL
Sbjct: 404 RRWHLQGVL 412


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  285 bits (729), Expect = 6e-77
 Identities = 173/433 (39%), Positives = 240/433 (55%), Gaps = 41/433 (9%)

Query: 2   PPCQPQRPLLLLLLLLACQPQVPSA--QVMDFLFEKWKLYGDQCHHNLSL---------L 50
           P   P    LLL +LLAC      A  ++ D L   W+   DQC   LS           
Sbjct: 3   PHLSPPLQQLLLPVLLACAAHSTGALPRLCDVLQVLWEEQ-DQCLQELSREQTGDLGTEQ 61

Query: 51  PPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGP 110
           P P    C   +D  SCWP +       + CP +L      ++  +F+ C  DG     P
Sbjct: 62  PVPG---CEGMWDNISCWPSSVPGRMVEVECPRFLRMLTS-RNGSLFRNCTQDGWSETFP 117

Query: 111 RGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLH 170
           R         C ++  +   +K  + +    +VMYTVGYS SL  LL+AL IL    +LH
Sbjct: 118 RPN-----LACGVNVNDSSNEKRHSYLLK-LKVMYTVGYSSSLVMLLVALGILCAFRRLH 171

Query: 171 CTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVF 230
           CTRN IH +LF SF+L+A S  + D +L +       DD++      D   AGC++  V 
Sbjct: 172 CTRNYIHMHLFVSFILRALSNFIKDAVLFS------SDDVTYC----DAHRAGCKLVMVL 221

Query: 231 MQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFE 290
            QY I+ANY WLLVEGLYLH LL ++   ER +   ++  GWG+P +FV  WA+ +   E
Sbjct: 222 FQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLE 281

Query: 291 NVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTD---YKFRL 347
           +V CW  N N   WWI+R PV L+ILINF +F+ I+++L+ KLR ++    +   YK RL
Sbjct: 282 DVGCWDINANASIWWIIRGPVILSILINFILFINILRILMRKLRTQETRGNEVSHYK-RL 340

Query: 348 AKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEV 407
           A+STL LIPL G+H +VFAF  ++  +      +LFF+L L SFQGL+VAVLYCFLN EV
Sbjct: 341 ARSTLLLIPLFGIHYIVFAFSPEDAME-----IQLFFELALGSFQGLVVAVLYCFLNGEV 395

Query: 408 QSELRRRWHRWRL 420
           Q E++++W +W L
Sbjct: 396 QLEVQKKWQQWHL 408


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  247 bits (631), Expect = 1e-65
 Identities = 146/364 (40%), Positives = 208/364 (57%), Gaps = 31/364 (8%)

Query: 58  CNRTFDKYSCWPDTPANTTANISCPW-YLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWR 116
           C+  +D  +CW       T  + CP  +  ++ K  +  + K C  DG          W 
Sbjct: 52  CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGN--ISKNCTSDG----------WS 99

Query: 117 DASQCQMDGEEIEVQKEVAKM--YSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRN 174
           +     +D       ++ +K+  Y   + +YT+GYS+SL +L     IL    KLHCTRN
Sbjct: 100 ETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRN 159

Query: 175 AIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234
            IH NLF SF+L+A SVLV D +L +        D   S+W+      GC+++ VF+QY 
Sbjct: 160 YIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPD-QPSSWV------GCKLSLVFLQYC 212

Query: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294
           I+AN+ WLLVEGLYLH LL +A LP R  F  YL IGWG P + +  W   +   E+  C
Sbjct: 213 IMANFFWLLVEGLYLHTLL-VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGC 271

Query: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTD---YKFRLAKST 351
           W +ND+   WW++R P+ ++I++NF +F+ I+++L+ KL +  +   D   YK RLAKST
Sbjct: 272 WDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYK-RLAKST 330

Query: 352 LTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSEL 411
           L LIPL GVH +VFA      +       ++ F+L L SFQGL+VAVLYCFLN EVQ EL
Sbjct: 331 LLLIPLFGVHYMVFAVFPISISS----KYQILFELCLGSFQGLVVAVLYCFLNSEVQCEL 386

Query: 412 RRRW 415
           +R+W
Sbjct: 387 KRKW 390


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  244 bits (624), Expect = 1e-64
 Identities = 125/287 (43%), Positives = 176/287 (61%), Gaps = 16/287 (5%)

Query: 138 YSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGL 197
           Y S + +YTVGYS SL  L  A+ IL    KLHCTRN IH NLF SF+L+A SV + D +
Sbjct: 150 YLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWI 209

Query: 198 LRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLAT 257
           L   Y+++  +   +ST         C+   VF  Y +V+NY WL +EGLYL  LL    
Sbjct: 210 L---YAEQDSNHCFIST-------VECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETF 259

Query: 258 LPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILI 317
            PER +F  Y  IGWG P + V  WA ++  F++  CW  ND+   WW+++ PV  +I++
Sbjct: 260 FPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMV 319

Query: 318 NFFIFVRIVQLLVAKLRARQM--HHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQG 375
           NF +F+ I+ +LV KL++  M  + +    RLA+STL LIPL G+H  VFAF      + 
Sbjct: 320 NFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAF----SPEN 375

Query: 376 TLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGK 422
             +  +L F+L L SFQG +VAVLYCFLN EVQ+E++R+W  W++ +
Sbjct: 376 VSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNR 422


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  240 bits (613), Expect = 2e-63
 Identities = 143/406 (35%), Positives = 210/406 (51%), Gaps = 35/406 (8%)

Query: 58  CNRTFDKYSCWPDTPANTTANISCPWYL-PWHHKVQHRFVFKRCGPDGQWVRGP-RGQPW 115
           C   +D   CWP         + CP Y+  ++HK      ++RC  +G W   P   + W
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHKGH---AYRRCDRNGSWELVPGHNRTW 164

Query: 116 RDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNA 175
            + S+C         ++EV   +    ++YTVGYS+SL +L +A+ IL    +LHCTRN 
Sbjct: 165 ANYSECVKFLTNETREREV---FDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNY 221

Query: 176 IHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVA------------- 222
           IH +LF SF+L+A S+ V D +L   YS    D+    T     A+A             
Sbjct: 222 IHMHLFLSFMLRAVSIFVKDAVL---YSGATLDEAERLTEEELRAIAQAPPPPATAAAGY 278

Query: 223 -GCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVP 281
            GCRVA  F  Y +  NY W+LVEGLYLH+L+ +A   E+ +   +   GWG P +FV  
Sbjct: 279 AGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAV 338

Query: 282 WAVVKCLFENVQCWT-SNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHH 340
           W  V+    N  CW  S+ N    WI++ P+  +I++NF +F+ IV++L  KLR      
Sbjct: 339 WVSVRATLANTGCWDLSSGNKK--WIIQVPILASIVLNFILFINIVRVLATKLRETNAGR 396

Query: 341 TDYKF---RLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVA 397
            D +    +L KSTL L+PL GVH +VF         GTL   ++ +++  +SFQG  VA
Sbjct: 397 CDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVA 456

Query: 398 VLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGHGP 443
           ++YCF N EVQ+E+++ W RW L      +        SSS  +GP
Sbjct: 457 IIYCFCNGEVQAEIKKSWSRWTLAL----DFKRKARSGSSSYSYGP 498


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  234 bits (597), Expect = 1e-61
 Identities = 138/412 (33%), Positives = 214/412 (51%), Gaps = 23/412 (5%)

Query: 42  QCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFV-FKRC 100
           QC  N++      E  C   +D   CWP       + + CP   P+ +   H+ V F+ C
Sbjct: 47  QCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCP---PYIYDFNHKGVAFRHC 103

Query: 101 GPDGQW-VRGPRGQPWRDASQC-QMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLL 158
            P+G W       + W + S C +    +I + K+  + +    VMYTVGYS+S G+L +
Sbjct: 104 NPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQ--EFFERLYVMYTVGYSISFGSLAV 161

Query: 159 ALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSV------ 212
           A+ I+G   +LHCTRN IH +LF SF+L+A+S+ V D ++      K  + L +      
Sbjct: 162 AILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDPQN 221

Query: 213 ---STWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLG 269
              +T +      GC++A V   Y +  NY W+LVEGLYLHNL+ +A   +  +   ++ 
Sbjct: 222 SIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGFIL 281

Query: 270 IGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLL 329
           IGWG P  FV  WAV +    + +CW  +      WI + P+  AI +NF +F+  V++L
Sbjct: 282 IGWGFPAAFVAAWAVARATLADARCWELSAG-DIKWIYQAPILAAIGLNFILFLNTVRVL 340

Query: 330 VAKLRARQM--HHTDYKFR-LAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDL 386
             K+       H T  ++R LAKSTL L+ + GVH +VF  +      G     ++  +L
Sbjct: 341 ATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFT-GLGWEIRMHCEL 399

Query: 387 FLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSS 438
           F +SFQG  V+++YC+ N EVQ+E+++ W RW L  V W+       R   S
Sbjct: 400 FFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNL-SVDWKRTPPCGSRRCGS 450


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  231 bits (589), Expect = 1e-60
 Identities = 132/367 (35%), Positives = 200/367 (54%), Gaps = 25/367 (6%)

Query: 52  PPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPR 111
           P T L C  T+D   CWP   +     + CP +   H   +   V + C   G     P 
Sbjct: 49  PNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVKRDCTITGWSEPFP- 106

Query: 112 GQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHC 171
             P+  A  C +    +E+  E    +S+ +++YTVG+S+S+ AL +A+ IL  L +LHC
Sbjct: 107 --PYPVA--CPVP---LELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHC 159

Query: 172 TRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFM 231
            RN +H  LF +F+LKA +V + D  L   +     D  S ST L       C+V+    
Sbjct: 160 PRNYVHTQLFTTFILKAGAVFLKDAAL---FHSDDTDHCSFSTVL-------CKVSVAAS 209

Query: 232 QYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFEN 291
            +  + N+ WLL E +YL+ LL   +   R  F   +  GWG P+LF   W   K  FE+
Sbjct: 210 HFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFED 269

Query: 292 VQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQ--MHHTDYKFRLAK 349
           + CW  +D   +WWI++ P+ L++ +NF +F+ I+++LV KL   Q  +H     +RL+K
Sbjct: 270 IACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSK 329

Query: 350 STLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQS 409
           STL LIPL G+H ++F F+ D    G     +L  +L L SFQG +VA+LYCFLN+EV++
Sbjct: 330 STLFLIPLFGIHYIIFNFLPDNAGLG----IRLPLELGLGSFQGFIVAILYCFLNQEVRT 385

Query: 410 ELRRRWH 416
           E+ R+WH
Sbjct: 386 EISRKWH 392


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  196 bits (497), Expect = 5e-50
 Identities = 132/417 (31%), Positives = 201/417 (48%), Gaps = 42/417 (10%)

Query: 6   PQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKY 65
           PQ  L+  LLLL   P   S Q             DQ   +LSL    + L CN + D  
Sbjct: 5   PQLRLVKALLLLGLNPVSASLQ-------------DQHCESLSLASNISGLQCNASVDLI 51

Query: 66  -SCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMD 124
            +CWP +PA       CP +            ++ C  +G W          + S+CQ  
Sbjct: 52  GTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV------NYSECQ-- 103

Query: 125 GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASF 184
            E +  +K+    Y    ++  +G+ +SL ALL+A  +   L  + C RN IH NL ++F
Sbjct: 104 -EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162

Query: 185 VLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLV 244
           +L+ ++  V+               L++S  +    V  CR+      Y  V N+ W+  
Sbjct: 163 ILRNATWFVVQ--------------LTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFG 208

Query: 245 EGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFW 304
           EG YLH  + L    +R    +++ IGWG P   +V WA+ K  ++N +CW      G +
Sbjct: 209 EGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGK-RPGVY 267

Query: 305 --WILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHE 362
             +I + P+ L +LINF     IV++L+ KLRA     T    +  K+TL L+PLLG+  
Sbjct: 268 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 327

Query: 363 VVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWR 419
           ++F FV     +   R   ++F+ FL SFQG  V+V YCFLN EV+S +R+RWHRW+
Sbjct: 328 MLF-FVNPGEDE-VSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQ 382


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  187 bits (476), Expect = 1e-47
 Identities = 117/369 (31%), Positives = 188/369 (50%), Gaps = 35/369 (9%)

Query: 58  CNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRG-QPWR 116
           CNRT+D + CW D  A T +   CP Y       +   V K C  DG W R P   + W 
Sbjct: 65  CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEK--VTKICDQDGNWFRHPASNRTWT 122

Query: 117 DASQCQMDGEEIEVQKEVAKMYSSFQVMYT--VGYSLSLGALLLALAILGGLSKLHCTRN 174
           + +QC ++  E        K+ ++  + Y   +G+ LS+ +LL++L I      L C R 
Sbjct: 123 NYTQCNVNTHE--------KVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRI 174

Query: 175 AIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234
            +H NLF SFV   +SV+ I  L     +Q +     VS          C+V+     Y 
Sbjct: 175 TLHKNLFFSFV--CNSVVTIIHLTAVANNQALVATNPVS----------CKVSQFIHLYL 222

Query: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294
           +  NY W+L EG+YLH L+ +A   E+     Y  +GWG P++     A+ + L+ N  C
Sbjct: 223 MGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNC 282

Query: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTL 354
           W S+D     +I+  P+  A+L+N F  + IV++L+ KL+      ++   +  ++TL L
Sbjct: 283 WISSDT-HLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLIL 341

Query: 355 IPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDL---FLSSFQGLLVAVLYCFLNKEVQSEL 411
           +PLLG+  V+  +      +G +  A+  +D     L  FQGLLV+ ++CF N EVQ+ L
Sbjct: 342 VPLLGIEFVLIPW----RPEGKI--AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAIL 395

Query: 412 RRRWHRWRL 420
           RR W+++++
Sbjct: 396 RRNWNQYKI 404


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  186 bits (472), Expect = 4e-47
 Identities = 115/377 (30%), Positives = 190/377 (50%), Gaps = 38/377 (10%)

Query: 58  CNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRG-QPWR 116
           CNRT+D + CW DTPA   +   CP Y P     +   V K C   G W + P   + W 
Sbjct: 72  CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEK--VTKYCDEKGVWFKHPENNRTWS 129

Query: 117 DASQCQMDGEEIEVQKEVAKMYSSFQVMYT--VGYSLSLGALLLALAILGGLSKLHCTRN 174
           + + C     E        K+ +++ + Y   VG+SLS+  L+++L I      L C R 
Sbjct: 130 NYTMCNAFTPE--------KLKNAYVLYYLAIVGHSLSIFTLVISLGIFVFFRSLGCQRV 181

Query: 175 AIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234
            +H N+F +++L  +S+++I  L+    + ++     VS          C++   F QY 
Sbjct: 182 TLHKNMFLTYIL--NSMIIIIHLVEVVPNGELVRRDPVS----------CKILHFFHQYM 229

Query: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294
           +  NY W+L EG+YLH L+ +A   E+     Y  +GWG P++     A+ + ++ N  C
Sbjct: 230 MACNYFWMLCEGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNC 289

Query: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTL 354
           W S +     +I+  PV  A+++NFF  + IV++LV K+R      +    +  K+T+ L
Sbjct: 290 WLSVET-HLLYIIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMIL 348

Query: 355 IPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSS---FQGLLVAVLYCFLNKEVQSEL 411
           +PLLG+  VVF +       G +      +D  + S   FQG  VA +YCF N EVQ+ +
Sbjct: 349 VPLLGIQFVVFPWRPSNKMLGKI------YDYVMHSLIHFQGFFVATIYCFCNNEVQTTV 402

Query: 412 RRRWHRWRLGKVLWEER 428
           +R+W ++   K+ W +R
Sbjct: 403 KRQWAQF---KIQWNQR 416


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  182 bits (461), Expect = 8e-46
 Identities = 113/364 (31%), Positives = 172/364 (47%), Gaps = 27/364 (7%)

Query: 58  CNRTFDKY-SCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWR 116
           CN T D+  +CWP + A       CP Y         R  ++ C  +G W          
Sbjct: 40  CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKI------ 93

Query: 117 DASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAI 176
           + SQC+   ++   Q++    Y    V+  +G+ +S+ AL+ A  +   L  + C RN I
Sbjct: 94  NYSQCEPILDD--KQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVI 151

Query: 177 HANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIV 236
           H NL  +F+L+     ++                 V   + +     CR       Y +V
Sbjct: 152 HWNLITTFILRNVMWFLLQ---------------LVDHEVHESNEVWCRCITTIFNYFVV 196

Query: 237 ANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWT 296
            N+ W+ VEG YLH  + +    ER    L+L IGW  P   +V WA+ K  +EN QCW 
Sbjct: 197 TNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWF 256

Query: 297 SNDNMGFW-WILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLI 355
             +      +I + P+ L +LINF     IV++L+ KLRA     T    +  K+TL L+
Sbjct: 257 GKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLL 316

Query: 356 PLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRW 415
           PLLG+  ++F     E     +    ++F+ FL SFQG  V+V YCF N EV+S +R+RW
Sbjct: 317 PLLGITYMLFFVNPGEDDLSQIMF--IYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRW 374

Query: 416 HRWR 419
           HRW+
Sbjct: 375 HRWQ 378


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  181 bits (459), Expect = 1e-45
 Identities = 133/446 (29%), Positives = 202/446 (45%), Gaps = 71/446 (15%)

Query: 6   PQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKY 65
           PQ  L+  LLLL   P   S Q             DQ   +LSL    + L CN + D  
Sbjct: 5   PQLRLVKALLLLGLNPVSASLQ-------------DQHCESLSLASNISGLQCNASVDLI 51

Query: 66  -SCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMD 124
            +CWP +PA       CP +            ++ C  +G W          + S+CQ  
Sbjct: 52  GTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV------NYSECQ-- 103

Query: 125 GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAIL---------------GGLS-- 167
            E +  +K+    Y    ++  +G+ +SL ALL+A  +                G L   
Sbjct: 104 -EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVG 162

Query: 168 ------------KLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTW 215
                        + C RN IH NL ++F+L+ ++  V+               L++S  
Sbjct: 163 APWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQ--------------LTMSPE 208

Query: 216 LSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAP 275
           +    V  CR+      Y  V N+ W+  EG YLH  + L    +R    +++ IGWG P
Sbjct: 209 VHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVP 268

Query: 276 MLFVVPWAVVKCLFENVQCWTSNDNMGFW--WILRFPVFLAILINFFIFVRIVQLLVAKL 333
              +V WA+ K  ++N +CW      G +  +I + P+ L +LINF     IV++L+ KL
Sbjct: 269 FPIIVAWAIGKLYYDNEKCWFGK-RPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKL 327

Query: 334 RARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQG 393
           RA     T    +  K+TL L+PLLG+  ++F FV     +   R   ++F+ FL SFQG
Sbjct: 328 RASTTSETIQYRKAVKATLVLLPLLGITYMLF-FVNPGEDE-VSRVVFIYFNSFLESFQG 385

Query: 394 LLVAVLYCFLNKEVQSELRRRWHRWR 419
             V+V YCFLN EV+S +R+RWHRW+
Sbjct: 386 FFVSVFYCFLNSEVRSAIRKRWHRWQ 411


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  176 bits (446), Expect = 4e-44
 Identities = 106/325 (32%), Positives = 168/325 (51%), Gaps = 28/325 (8%)

Query: 97  FKRCGPDGQWVRGPRGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGAL 156
           ++ C  +G W          + S+CQ   E +  +K+    Y    ++  +G+ +SL AL
Sbjct: 44  YRECLANGSWAARV------NYSECQ---EILNEEKKSKVHYHVAVIINYLGHCISLVAL 94

Query: 157 LLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWL 216
           L+A  +   L  + C RN IH NL ++F+L+ ++  V+               L++S  +
Sbjct: 95  LVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQ--------------LTMSPEV 140

Query: 217 SDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPM 276
               V  CR+      Y  V N+ W+  EG YLH  + L    +R    +++ IGWG P 
Sbjct: 141 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 200

Query: 277 LFVVPWAVVKCLFENVQCWTSNDNMGFW--WILRFPVFLAILINFFIFVRIVQLLVAKLR 334
             +V WA+ K  ++N +CW      G +  +I + P+ L +LINF     IV++L+ KLR
Sbjct: 201 PIIVAWAIGKLYYDNEKCWFGK-RPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR 259

Query: 335 ARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGL 394
           A     T    +  K+TL L+PLLG+  ++F FV     +   R   ++F+ FL SFQG 
Sbjct: 260 ASTTSETIQYRKAVKATLVLLPLLGITYMLF-FVNPGEDE-VSRVVFIYFNSFLESFQGF 317

Query: 395 LVAVLYCFLNKEVQSELRRRWHRWR 419
            V+V YCFLN EV+S +R+RWHRW+
Sbjct: 318 FVSVFYCFLNSEVRSAIRKRWHRWQ 342


>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  166 bits (420), Expect = 4e-41
 Identities = 123/417 (29%), Positives = 191/417 (45%), Gaps = 56/417 (13%)

Query: 6   PQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKY 65
           PQ  L+  LLLL   P   S Q             DQ   +LSL    + L CN + D  
Sbjct: 5   PQLRLVKALLLLGLNPVSASLQ-------------DQHCESLSLASNISGLQCNASVDLI 51

Query: 66  -SCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMD 124
            +CWP +PA       CP +            ++ C  +G W          + S+CQ  
Sbjct: 52  GTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV------NYSECQ-- 103

Query: 125 GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASF 184
            E +  +K+    Y    ++  +G+ +SL ALL+A  +   L  + C RN IH NL ++F
Sbjct: 104 -EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162

Query: 185 VLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLV 244
           +L+ ++  V+               L++S  +    V  CR+      Y  V N+ W+  
Sbjct: 163 ILRNATWFVVQ--------------LTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFG 208

Query: 245 EGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFW 304
           EG YLH  + L    +R    +++ IGWG P   +V WA+ K  ++N +CW      G +
Sbjct: 209 EGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGK-RPGVY 267

Query: 305 --WILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHE 362
             +I + P+ L +LINF     IV++L+ KLRA     T    +  K+TL L+PLLG+  
Sbjct: 268 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 327

Query: 363 VVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWR 419
           ++F FV     +   R   ++F+ FL SFQ              V+S +R+RWHRW+
Sbjct: 328 MLF-FVNPGEDE-VSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQ 368


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  160 bits (406), Expect = 2e-39
 Identities = 94/286 (32%), Positives = 146/286 (51%), Gaps = 19/286 (6%)

Query: 52  PPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPR 111
           P T L C  T+D   CWP   +     + CP +   H   +   V + C   G     P 
Sbjct: 49  PNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS-HFSSESGAVKRDCTITGWSEPFP- 106

Query: 112 GQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHC 171
             P+  A  C +    +E+  E    +S+ +++YTVG+S+S+ AL +A+ IL  L +LHC
Sbjct: 107 --PYPVA--CPVP---LELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHC 159

Query: 172 TRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFM 231
            RN +H  LF +F+LKA +V + D  L   +     D  S ST L       C+V+    
Sbjct: 160 PRNYVHTQLFTTFILKAGAVFLKDAAL---FHSDDTDHCSFSTVL-------CKVSVAAS 209

Query: 232 QYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFEN 291
            +  + N+ WLL E +YL+ LL   +   R  F   +  GWG P+LF   W   K  FE+
Sbjct: 210 HFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFED 269

Query: 292 VQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQ 337
           + CW  +D   +WWI++ P+ L++ +NF +F+ I+++LV KL   Q
Sbjct: 270 IACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQ 315


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 82/285 (28%), Positives = 135/285 (47%), Gaps = 41/285 (14%)

Query: 147 VGYSLS---LGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYS 203
           VG SLS   L A L+  A+L  +S +   R  IHANL  SF +  + VL++         
Sbjct: 572 VGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANL--SFAVLVAQVLLL--------- 620

Query: 204 QKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSF 263
                   +S  L  G    C+V AV + Y  ++ + W+LVEGL+L++++      E S 
Sbjct: 621 --------ISFRLEPGTTP-CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSK 671

Query: 264 FSLYLGIGWGAPMLFVV---PWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILINFF 320
              Y G+GWG P+L  +    +A+      N  CW S  + G  W    P    I++N  
Sbjct: 672 HRYYYGMGWGFPLLICIISLSFAMDSYGTSN-NCWLSLAS-GAIWAFVAPALFVIVVNIG 729

Query: 321 IFVRIVQLLVAKLRA--RQMHHTDYKFRL-AKSTLTLIPLLGVHEVVFAFVTDEHAQGTL 377
           I + + + +++++ A   ++H     F+L AK+   L+P+LG   V      +       
Sbjct: 730 ILIAVTR-VISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVN------- 781

Query: 378 RSAKLFFDLF--LSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL 420
             A +F  +F  L+S QGL + + +C LN EV++  + +   W L
Sbjct: 782 GCAVVFQYMFATLNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSL 826


>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
          Length = 786

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 78/276 (28%), Positives = 119/276 (43%), Gaps = 38/276 (13%)

Query: 147 VGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKI 206
           VG +LSL  LLL +     +  +  +R  IH +L     L   S + + G+         
Sbjct: 504 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHL--CICLFVGSTIFLAGIE-------- 553

Query: 207 GDDLSVSTWLSDGAVAG--CRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFF 264
                     ++G   G  CR+ A  + Y  +A +CW+ +EGL L+ L+      +    
Sbjct: 554 ----------NEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLST 603

Query: 265 SLYLGIGWGAPMLFVVPWAVV--KCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIF 322
                IG+G P+L V   A +  K       CW   +  GF W    PV   IL N  IF
Sbjct: 604 RWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE-QGFLWSFLGPVTFIILCNAVIF 662

Query: 323 VRIVQLLVAKLRARQMHHTDYKFRLAKS-TLTLIP---LLGVHEVVFAFVTDEHAQGTLR 378
           V  V  L  K    +++    K + A++ T+T I    LLG   V   F+ D+      R
Sbjct: 663 VTTVWKLTQKF--SEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDD------R 714

Query: 379 SAKL-FFDLFLSSFQGLLVAVLYCFLNKEVQSELRR 413
           S  L +    L+  QG  + +L+C LNK+V+ E R+
Sbjct: 715 SLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRK 750


>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
          Length = 742

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 78/276 (28%), Positives = 119/276 (43%), Gaps = 38/276 (13%)

Query: 147 VGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKI 206
           VG +LSL  LLL +     +  +  +R  IH +L     L   S + + G+         
Sbjct: 460 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHL--CICLFVGSTIFLAGIE-------- 509

Query: 207 GDDLSVSTWLSDGAVAG--CRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFF 264
                     ++G   G  CR+ A  + Y  +A +CW+ +EGL L+ L+      +    
Sbjct: 510 ----------NEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLST 559

Query: 265 SLYLGIGWGAPMLFVVPWAVV--KCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIF 322
                IG+G P+L V   A +  K       CW   +  GF W    PV   IL N  IF
Sbjct: 560 RWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE-QGFLWSFLGPVTFIILCNAVIF 618

Query: 323 VRIVQLLVAKLRARQMHHTDYKFRLAKS-TLTLIP---LLGVHEVVFAFVTDEHAQGTLR 378
           V  V  L  K    +++    K + A++ T+T I    LLG   V   F+ D+      R
Sbjct: 619 VTTVWKLTQKF--SEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDD------R 670

Query: 379 SAKL-FFDLFLSSFQGLLVAVLYCFLNKEVQSELRR 413
           S  L +    L+  QG  + +L+C LNK+V+ E R+
Sbjct: 671 SLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRK 706


>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
          Length = 835

 Score = 69.7 bits (169), Expect = 5e-12
 Identities = 78/276 (28%), Positives = 119/276 (43%), Gaps = 38/276 (13%)

Query: 147 VGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKI 206
           VG +LSL  LLL +     +  +  +R  IH +L     L   S + + G+         
Sbjct: 553 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHL--CICLFVGSTIFLAGIE-------- 602

Query: 207 GDDLSVSTWLSDGAVAG--CRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFF 264
                     ++G   G  CR+ A  + Y  +A +CW+ +EGL L+ L+      +    
Sbjct: 603 ----------NEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLST 652

Query: 265 SLYLGIGWGAPMLFVVPWAVV--KCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIF 322
                IG+G P+L V   A +  K       CW   +  GF W    PV   IL N  IF
Sbjct: 653 RWLCLIGYGVPLLIVGVSAAIYSKGYGRPRYCWLDFE-QGFLWSFLGPVTFIILCNAVIF 711

Query: 323 VRIVQLLVAKLRARQMHHTDYKFRLAKS-TLTLIP---LLGVHEVVFAFVTDEHAQGTLR 378
           V  V  L  K    +++    K + A++ T+T I    LLG   V   F+ D+      R
Sbjct: 712 VTTVWKLTQKF--SEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDD------R 763

Query: 379 SAKL-FFDLFLSSFQGLLVAVLYCFLNKEVQSELRR 413
           S  L +    L+  QG  + +L+C LNK+V+ E R+
Sbjct: 764 SLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRK 799


>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
            sapiens]
          Length = 3312

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 76/302 (25%), Positives = 122/302 (40%), Gaps = 53/302 (17%)

Query: 150  SLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDD 209
            ++S+ AL+L  AIL  L  L      IHAN+ A+  L  + +L + G+ RT ++Q +   
Sbjct: 2548 AVSVAALVLTAAILLSLRSLKSNVRGIHANVAAA--LGVAELLFLLGIHRT-HNQLV--- 2601

Query: 210  LSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLG 269
                          C   A+ + Y  ++ + WL V+GL+L+ +       +R     Y  
Sbjct: 2602 --------------CTAVAILLHYFFLSTFAWLFVQGLHLYRMQVEPRNVDRGAMRFYHA 2647

Query: 270  IGWGAP-MLFVVPWAVVKCLFENVQ-CWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQ 327
            +GWG P +L  +   +    + N   CW S  +    W    PV L I++N  +F+   +
Sbjct: 2648 LGWGVPAVLLGLAVGLDPEGYGNPDFCWIS-VHEPLIWSFAGPVVLVIVMNGTMFLLAAR 2706

Query: 328  LLV------AKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAK 381
                     AK  +     + +   L  S   L  LL V+  + AF              
Sbjct: 2707 TSCSTGQREAKKTSALTLRSSFLLLLLVSASWLFGLLAVNHSILAF-------------- 2752

Query: 382  LFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGH 441
             +    L   QGL V +L+C LN    ++ R  W    LG      R  +   A  +PG 
Sbjct: 2753 HYLHAGLCGLQGLAVLLLFCVLN----ADARAAWMPACLG------RKAAPEEARPAPGL 2802

Query: 442  GP 443
            GP
Sbjct: 2803 GP 2804


>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
          Length = 963

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 75/292 (25%), Positives = 113/292 (38%), Gaps = 50/292 (17%)

Query: 139 SSFQVMYTVGYSLSLGALLLA--LAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDG 196
           S  + +  VG  +S  AL     L ++ G+ K    R  +H NL         S+   +G
Sbjct: 656 SLLRTLSFVGCGVSFCALTTTFLLFLVAGVPKSE--RTTVHKNL-------TFSLASAEG 706

Query: 197 LLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLA 256
            L T            S W     VA C    V M +  +  + W+LVEGL L   +   
Sbjct: 707 FLMT------------SEWAKANEVA-CVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAV 753

Query: 257 TLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFEN-----VQCWTSNDNMGFWWILRFPV 311
           ++       LY   GWG P+  V   AV   +  +       CW  N +    W    PV
Sbjct: 754 SMHPGPGMRLYHATGWGVPVGIV---AVTLAMLPHDYVAPGHCWL-NVHTNAIWAFVGPV 809

Query: 312 FLAILINFFIFVRIVQLLVAKLRAR----------QMHHTDYKFRLAKSTLTLIPLLGVH 361
              +  N  I  R+V + V+  R R          Q       +   K  L L+P+LG+ 
Sbjct: 810 LFVLTANTCILARVVMITVSSARRRARMLSPQPCLQQQIWTQIWATVKPVLVLLPVLGLT 869

Query: 362 EVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRR 413
            +    V        L  A  +  + L+S QGL + ++Y   N+EV+S L+R
Sbjct: 870 WLAGILV-------HLSPAWAYAAVGLNSIQGLYIFLVYAACNEEVRSALQR 914


>gi|7656967 cadherin EGF LAG seven-pass G-type receptor 1 [Homo
            sapiens]
          Length = 3014

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 69/277 (24%), Positives = 115/277 (41%), Gaps = 54/277 (19%)

Query: 150  SLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDD 209
            SLSL ALL+A  +L  +  L    ++IH +L  +  L  S ++ + G+ +T         
Sbjct: 2477 SLSLAALLVAFVLLSLVRMLRSNLHSIHKHLAVALFL--SQLVFVIGINQTE-------- 2526

Query: 210  LSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLG 269
               + +L       C V A+ + Y  ++ + W LVE L+++ +L      +      Y  
Sbjct: 2527 ---NPFL-------CTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYV 2576

Query: 270  IGWGAPMLFVVPWAVVKCLFENVQ---------CWTSNDNMGFWWILRFPVFLAILINFF 320
            +GWG P       A+V  L   +          CW S  +    W    P+   I+IN  
Sbjct: 2577 VGWGIP-------AIVTGLAVGLDPQGYGNPDFCWLSLQDT-LIWSFAGPIGAVIIIN-- 2626

Query: 321  IFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTL--- 377
                +  +L AK+  ++ HH   K         ++ LL    ++   ++     G L   
Sbjct: 2627 ---TVTSVLSAKVSCQRKHHYYGK-------KGIVSLLRTAFLLLLLISATWLLGLLAVN 2676

Query: 378  RSAKLFFDLF--LSSFQGLLVAVLYCFLNKEVQSELR 412
            R A  F  LF   S  QG  V + +C LN+EV+  L+
Sbjct: 2677 RDALSFHYLFAIFSGLQGPFVLLFHCVLNQEVRKHLK 2713


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 74/293 (25%), Positives = 124/293 (42%), Gaps = 33/293 (11%)

Query: 128  IEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLK 187
            +EV+   A       V+  VG  LSL  LL+ +        L   RN IH NL  S  L 
Sbjct: 864  VEVKHSDAVHDLLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCIS--LF 921

Query: 188  ASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGL 247
             + +L + G+ RT                 D  +A C V A  + +  +A + W+ +EG+
Sbjct: 922  VAELLFLIGINRT-----------------DQPIA-CAVFAALLHFFFLAAFTWMFLEGV 963

Query: 248  YLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVV--KCLFENVQCWTSNDNMGFWW 305
             L+ +L      E S    +  +G+G P L V   A V  +    +  CW   D   F W
Sbjct: 964  QLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTY-FIW 1022

Query: 306  ILRFPVFLAILIN-FFIFVRIVQLL--VAKLRAR-----QMHHTDYKFRLAKSTLTLIPL 357
                P  L I++N  F+ + + ++    A L+        +++ D +  +    +  I L
Sbjct: 1023 SFIGPATLIIMLNVIFLGIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIAL 1082

Query: 358  LGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSE 410
            L +  + +AF      + T+  A LF     +S QG+ + + +C L K+V+ E
Sbjct: 1083 LCLLGLTWAFGLMYINESTVIMAYLF--TIFNSLQGMFIFIFHCVLQKKVRKE 1133


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 76/310 (24%), Positives = 125/310 (40%), Gaps = 40/310 (12%)

Query: 140 SFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLR 199
           S  ++  VG  +SL  L+LA+A       +      +H +L    +L  +  L + G+ +
Sbjct: 601 SLYIISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLL--AKTLFLAGIHK 658

Query: 200 TRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEG----LYLHNLLGL 255
           T                      GC + A F+ Y  +A + W+LVE     L + NL  +
Sbjct: 659 TDNKM------------------GCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVV 700

Query: 256 ATLPERSFFSLYL-GIGWGAPMLFVVPWAVVKCLFENV--QCWTSNDNMGFWWILRFPVF 312
                R+   L++   G+G PML VV  A V+     +  +CW  N   GF W    PV 
Sbjct: 701 NYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWL-NTETGFIWSFLGPVC 759

Query: 313 LAILINFFIFVRIVQLLVAKLRARQMHHTDYKFR--LAKSTLTLIPLLGVHEVVFAFVTD 370
             I+IN  +    + +L  +L +     +  K    L       + +LG   V+  F   
Sbjct: 760 TVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQI- 818

Query: 371 EHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVL-WEERN 429
               G +     +    ++S QG  + +++C LN +V+ E    + RW  GK     +  
Sbjct: 819 ----GPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREE----YKRWITGKTKPSSQSQ 870

Query: 430 TSNHRASSSP 439
           TS    SS P
Sbjct: 871 TSRILLSSMP 880


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 70/272 (25%), Positives = 115/272 (42%), Gaps = 30/272 (11%)

Query: 143  VMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRY 202
            V+  VG  +SL  L + ++    L  L   RN IH NL  +  L  + +L + G+ +T+Y
Sbjct: 862  VITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFL--AELLFLVGIDKTQY 919

Query: 203  SQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERS 262
                                 C + A  + Y  +A + WL +EG++L+ LL      E S
Sbjct: 920  E------------------IACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYS 961

Query: 263  FFSLYLGIGWGAPMLFVVPWAVV--KCLFENVQCWTSNDNMGFWWILRFPVFLAILINF- 319
                Y   G+  P L V   A +  +       CW   DN  F W    PV   I++N  
Sbjct: 962  RTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNY-FIWSFIGPVSFVIVVNLV 1020

Query: 320  FIFVRIVQLL-VAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLR 378
            F+ V + +++  + +        D     A   + L+ LLG   + +AF      + ++ 
Sbjct: 1021 FLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLG---LTWAFGLLFINKESVV 1077

Query: 379  SAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSE 410
             A LF     ++FQG+ + V +C L K+V  E
Sbjct: 1078 MAYLF--TTFNAFQGVFIFVFHCALQKKVHKE 1107


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 70/272 (25%), Positives = 115/272 (42%), Gaps = 30/272 (11%)

Query: 143  VMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRY 202
            V+  VG  +SL  L + ++    L  L   RN IH NL  +  L  + +L + G+ +T+Y
Sbjct: 857  VITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFL--AELLFLVGIDKTQY 914

Query: 203  SQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERS 262
                                 C + A  + Y  +A + WL +EG++L+ LL      E S
Sbjct: 915  E------------------IACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYS 956

Query: 263  FFSLYLGIGWGAPMLFVVPWAVV--KCLFENVQCWTSNDNMGFWWILRFPVFLAILINF- 319
                Y   G+  P L V   A +  +       CW   DN  F W    PV   I++N  
Sbjct: 957  RTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNY-FIWSFIGPVSFVIVVNLV 1015

Query: 320  FIFVRIVQLL-VAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLR 378
            F+ V + +++  + +        D     A   + L+ LLG   + +AF      + ++ 
Sbjct: 1016 FLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLG---LTWAFGLLFINKESVV 1072

Query: 379  SAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSE 410
             A LF     ++FQG+ + V +C L K+V  E
Sbjct: 1073 MAYLF--TTFNAFQGVFIFVFHCALQKKVHKE 1102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.462 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,056,876
Number of Sequences: 37866
Number of extensions: 881594
Number of successful extensions: 3440
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 40
Number of HSP's that attempted gapping in prelim test: 3239
Number of HSP's gapped (non-prelim): 99
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.