Search of human proteins with 4503937

Search of human proteins with 4503937

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503937 nipsnap homolog 2 [Homo sapiens]
         (286 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503937 nipsnap homolog 2 [Homo sapiens]                           602   e-173
gi|193211616 nipsnap homolog 1 [Homo sapiens]                         419   e-117
gi|21361743 nipsnap homolog 3B [Homo sapiens]                          65   5e-11
gi|22267436 nipsnap homolog 3A [Homo sapiens]                          65   9e-11
gi|190358504 SHC SH2-domain binding protein 1 [Homo sapiens]           33   0.29 
gi|75677365 dynein heavy chain domain 3 [Homo sapiens]                 29   4.1  
gi|71061468 centromere protein E [Homo sapiens]                        28   7.1  

>gi|4503937 nipsnap homolog 2 [Homo sapiens]
          Length = 286

 Score =  602 bits (1553), Expect = e-173
 Identities = 286/286 (100%), Positives = 286/286 (100%)

Query: 1   MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA 60
           MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA
Sbjct: 1   MAARVLRARGAAWAGGLLQRAAPCSLLPRLRTWTSSSNRSREDSWLKSLFVRKVDPRKDA 60

Query: 61  HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE 120
           HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE
Sbjct: 61  HSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHYPCTLVGTWNTWYGE 120

Query: 121 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP 180
           QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP
Sbjct: 121 QDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVP 180

Query: 181 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR 240
           RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR
Sbjct: 181 RSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGNEAVGGFFSQIGQLYMVHHLWAYR 240

Query: 241 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ 286
           DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ
Sbjct: 241 DLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSPLQ 286


>gi|193211616 nipsnap homolog 1 [Homo sapiens]
          Length = 284

 Score =  419 bits (1077), Expect = e-117
 Identities = 188/249 (75%), Positives = 219/249 (87%)

Query: 38  NRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVL 97
           ++  E SW +SLFV KVDPRKDAHS LL+KKETSNLYK+QFHNVKPE L+AYN + + VL
Sbjct: 36  SKDNEGSWFRSLFVHKVDPRKDAHSTLLSKKETSNLYKIQFHNVKPEYLDAYNSLTEAVL 95

Query: 98  PKIHEDKHYPCTLVGTWNTWYGEQDQAVHLWRYEGGYPALTEVMNKLRENKEFLEFRKAR 157
           PK+H D+ YPC+LVG WNTWYGEQDQAVHLWR+ GGYPAL + MNKL+ NKE+LEFR+ R
Sbjct: 96  PKLHLDEDYPCSLVGNWNTWYGEQDQAVHLWRFSGGYPALMDCMNKLKNNKEYLEFRRER 155

Query: 158 SDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQDGN 217
           S MLLSR+NQLLLEFSFWNEP PR GPNIYELR+Y+L+PGTMIEWGN WARAI++RQ+  
Sbjct: 156 SQMLLSRRNQLLLEFSFWNEPQPRMGPNIYELRTYKLKPGTMIEWGNNWARAIKYRQENQ 215

Query: 218 EAVGGFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIM 277
           EAVGGFFSQIG+LY+VHHLWAY+DLQ+RE+ RNAAW K GW+E VYYTVPL++ MESRIM
Sbjct: 216 EAVGGFFSQIGELYVVHHLWAYKDLQSREETRNAAWRKRGWDENVYYTVPLVRHMESRIM 275

Query: 278 IPLKTSPLQ 286
           IPLK SPLQ
Sbjct: 276 IPLKISPLQ 284


>gi|21361743 nipsnap homolog 3B [Homo sapiens]
          Length = 247

 Score = 65.5 bits (158), Expect = 5e-11
 Identities = 59/245 (24%), Positives = 109/245 (44%), Gaps = 12/245 (4%)

Query: 47  KSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYNKICQEVLPKIHEDKHY 106
           K+L  R + P+  +      ++     Y+ + + +KP  + A+    + +   IH    Y
Sbjct: 10  KALASRTLAPQVCSSFATGPRQYDGTFYEFRTYYLKPSNMNAF---MENLKKNIHLRTSY 66

Query: 107 PCTLVGTWNTWYGEQDQAV-HLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRK 165
              LVG W+  +G +   V H+W+Y+  +    EV   L   KE+ E     +   + ++
Sbjct: 67  S-ELVGFWSVEFGGRTNKVFHIWKYDN-FAHRAEVRKALANCKEWQEQSIIPNLARIDKQ 124

Query: 166 NQLLLEFSFWN--EPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQD--GNEAVG 221
              +     W+  E  P+ G  +YEL  +Q++PG    WG+ + RAI    +    + VG
Sbjct: 125 ETEITYLIPWSKLEKPPKEG--VYELAVFQMKPGGPALWGDAFERAINAHVNLGYTKVVG 182

Query: 222 GFFSQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLK 281
            F ++ G+L  VH LW      +R   R+ +         V  +V  +   ++ ++IP  
Sbjct: 183 VFHTEYGELNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPAS 242

Query: 282 TSPLQ 286
            SPL+
Sbjct: 243 FSPLK 247


>gi|22267436 nipsnap homolog 3A [Homo sapiens]
          Length = 247

 Score = 64.7 bits (156), Expect = 9e-11
 Identities = 49/182 (26%), Positives = 87/182 (47%), Gaps = 8/182 (4%)

Query: 110 LVGTWNTWYGEQDQAV-HLWRYEGGYPALTEVMNKLRENKEFLEFRKARSDMLLSRKNQL 168
           LVG W+  +G +   V H+W+Y+  +   TEV   L ++KE+ E     +  L+ ++   
Sbjct: 69  LVGYWSVEFGGRMNTVFHIWKYDN-FAHRTEVRKALAKDKEWQEQFLIPNLALIDKQESE 127

Query: 169 LLEFSFWN--EPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAIRFRQD--GNEAVGGFF 224
           +     W   E  P+ G  +YEL ++Q++PG    WG+ + RA+    +    + VG F 
Sbjct: 128 ITYLVPWCKLEKPPKEG--VYELATFQMKPGGPALWGDAFKRAVHAHVNLGYTKLVGVFH 185

Query: 225 SQIGQLYMVHHLWAYRDLQTREDIRNAAWHKHGWEELVYYTVPLIQEMESRIMIPLKTSP 284
           ++ G L  VH LW      +R   R+ +         V  +V  +   ++ ++IP   SP
Sbjct: 186 TEYGALNRVHVLWWNESADSRAAGRHKSHEDPRVVAAVRESVNYLVSQQNMLLIPTSFSP 245

Query: 285 LQ 286
           L+
Sbjct: 246 LK 247



 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 38/128 (29%), Positives = 57/128 (44%), Gaps = 3/128 (2%)

Query: 151 LEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLRPGTMIEWGNYWARAI 210
           L  R A +  L SR     +  SF   P    G   YE RSY L+P  M E+   + +  
Sbjct: 2   LVLRSALTRALASRTLAPQMCSSFATGPRQYDGI-FYEFRSYYLKPSKMNEFLENFEKNA 60

Query: 211 RFRQDGNEAVGGFFSQI-GQLYMVHHLWAYRDLQTREDIRNAAWHKHGW-EELVYYTVPL 268
             R   +E VG +  +  G++  V H+W Y +   R ++R A      W E+ +   + L
Sbjct: 61  HLRTAHSELVGYWSVEFGGRMNTVFHIWKYDNFAHRTEVRKALAKDKEWQEQFLIPNLAL 120

Query: 269 IQEMESRI 276
           I + ES I
Sbjct: 121 IDKQESEI 128


>gi|190358504 SHC SH2-domain binding protein 1 [Homo sapiens]
          Length = 672

 Score = 33.1 bits (74), Expect = 0.29
 Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 7/61 (11%)

Query: 31  RTWTSSSNRSREDSWLKSLFVRKVDPRKDAHSNLLAKKETSNLYKLQFHNVKPECLEAYN 90
           R+W    +   ED +    FVR V+PR   H ++L  +  S L  + +HN+  +C E+Y 
Sbjct: 207 RSW----DEEEEDEY--DYFVRCVEPRLRLHYDILEDRVPSGLI-VDYHNLLSQCEESYR 259

Query: 91  K 91
           K
Sbjct: 260 K 260


>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
          Length = 4427

 Score = 29.3 bits (64), Expect = 4.1
 Identities = 35/126 (27%), Positives = 48/126 (38%), Gaps = 17/126 (13%)

Query: 136  ALTEVMNKLRENKEFLEFRKARSDMLLSRKNQLLLEFSFWNEPVPRSGPNIYELRSYQLR 195
            AL E   KLRE  E LE  K + D  L++K +L  +       + R+G  +  L   + R
Sbjct: 3233 ALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKAR 3292

Query: 196  PGTMIEWGNYWARAIR-FRQDGNEAVGGFFSQIGQL-YMVHHLWAYRDLQTREDIRNAAW 253
                      W   ++   +D    VG        L YM   L  YRD     +I N  W
Sbjct: 3293 ----------WEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRD-----EIVNQIW 3337

Query: 254  HKHGWE 259
                WE
Sbjct: 3338 IGKIWE 3343


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 28.5 bits (62), Expect = 7.1
 Identities = 13/33 (39%), Positives = 22/33 (66%)

Query: 137  LTEVMNKLRENKEFLEFRKARSDMLLSRKNQLL 169
            ++EV  K+ E K+F E RKA+   L S ++++L
Sbjct: 1540 ISEVQEKVNELKQFKEHRKAKDSALQSIESKML 1572


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,313,266
Number of Sequences: 37866
Number of extensions: 486642
Number of successful extensions: 1141
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1128
Number of HSP's gapped (non-prelim): 8
length of query: 286
length of database: 18,247,518
effective HSP length: 101
effective length of query: 185
effective length of database: 14,423,052
effective search space: 2668264620
effective search space used: 2668264620
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.