Search of human proteins with 4503701

Search of human proteins with 4503701

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
         (206 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]        411   e-115
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]       195   2e-50
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo...   118   3e-27
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]        103   1e-22
gi|9789947 fibroblast growth factor 20 [Homo sapiens]                 103   1e-22
gi|153285461 fibroblast growth factor 2 [Homo sapiens]                102   2e-22
gi|4503691 fibroblast growth factor 16 [Homo sapiens]                  98   6e-21
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]       93   1e-19
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]      92   2e-19
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]       92   2e-19
gi|4758362 fibroblast growth factor 11 [Homo sapiens]                  89   3e-18
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]         88   6e-18
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]      86   3e-17
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]      86   3e-17
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]      86   3e-17
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]      86   3e-17
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]        86   3e-17
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]       86   3e-17
gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]       86   3e-17
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]       86   3e-17
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]         84   6e-17
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]        79   4e-15
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr...    72   3e-13
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot...    72   3e-13
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr...    72   3e-13
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr...    72   3e-13
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]        67   1e-11
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]        66   2e-11
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo...    64   9e-11
gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo...    64   1e-10

>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
          Length = 206

 Score =  411 bits (1057), Expect = e-115
 Identities = 206/206 (100%), Positives = 206/206 (100%)

Query: 1   MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV 60
           MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV
Sbjct: 1   MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV 60

Query: 61  AAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSP 120
           AAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSP
Sbjct: 61  AAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSP 120

Query: 121 VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIA 180
           VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIA
Sbjct: 121 VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIA 180

Query: 181 LSKNGKTKKGNRVSPTMKVTHFLPRL 206
           LSKNGKTKKGNRVSPTMKVTHFLPRL
Sbjct: 181 LSKNGKTKKGNRVSPTMKVTHFLPRL 206


>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
          Length = 208

 Score =  195 bits (496), Expect = 2e-50
 Identities = 109/202 (53%), Positives = 135/202 (66%), Gaps = 13/202 (6%)

Query: 5   GTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPVAAQP 64
           GT    +   +L+ ++ P      + A T  N TL     R W +L  LS +R  +A + 
Sbjct: 20  GTLWALVFLGILVGMVVP------SPAGTRANNTLLDS--RGWGTL--LSRSRAGLAGEI 69

Query: 65  KEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSPVERG 124
                +SG   YL+GIKR RRLYCNVGIGFHLQ LPDGRI G H +   SLLE+S VERG
Sbjct: 70  AGVNWESG---YLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEISTVERG 126

Query: 125 VVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIALSKN 184
           VVS+FGV S  FVAM+SKG+LY +P F +EC F+E LLPNNYNAYES  Y G +IALSK 
Sbjct: 127 VVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTYIALSKY 186

Query: 185 GKTKKGNRVSPTMKVTHFLPRL 206
           G+ K+G++VSP M VTHFLPR+
Sbjct: 187 GRVKRGSKVSPIMTVTHFLPRI 208


>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
           sapiens]
          Length = 268

 Score =  118 bits (296), Expect = 3e-27
 Identities = 74/195 (37%), Positives = 105/195 (53%), Gaps = 11/195 (5%)

Query: 20  LAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPVAAQPKEAA-VQSGAGDYLL 78
           LAP    G AA    P G+   +      ++ + S +  P A+   + + ++  +  +  
Sbjct: 26  LAPKGQPGPAATDRNPRGSSSRQSSS--SAMSSSSASSSPAASLGSQGSGLEQSSFQWSP 83

Query: 79  GIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSPVERGVVSIFGVASRFFVA 138
             +R   LYC VGIGFHLQ  PDG++ G+H     S+LE+  V +G+V I GV S  F+A
Sbjct: 84  SGRRTGSLYCRVGIGFHLQIYPDGKVNGSHEANMLSVLEIFAVSQGIVGIRGVFSNKFLA 143

Query: 139 MSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKG-- 190
           MS KGKL+ S  FTD+C F+E    N+YN Y S  +         ++AL+K GK K+G  
Sbjct: 144 MSKKGKLHASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCS 203

Query: 191 NRVSPTMKVTHFLPR 205
            RV P    THFLPR
Sbjct: 204 PRVKPQHISTHFLPR 218


>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
          Length = 208

 Score =  103 bits (257), Expect = 1e-22
 Identities = 59/138 (42%), Positives = 79/138 (57%), Gaps = 9/138 (6%)

Query: 75  DYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHAD-TRDSLLELSPVERGVVSIFGVAS 133
           D+L GI R R+LYC  G  FHL+  P+G I G   D +R  +LE   +  G+VSI GV S
Sbjct: 55  DHLKGILRRRQLYCRTG--FHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDS 112

Query: 134 RFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGM------FIALSKNGKT 187
             ++ M+ KG+LYGS   T EC F+E    N YN Y S  Y  +      ++AL+K+G  
Sbjct: 113 GLYLGMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTP 172

Query: 188 KKGNRVSPTMKVTHFLPR 205
           ++G R     K THFLPR
Sbjct: 173 REGTRTKRHQKFTHFLPR 190


>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
          Length = 211

 Score =  103 bits (257), Expect = 1e-22
 Identities = 68/163 (41%), Positives = 88/163 (53%), Gaps = 16/163 (9%)

Query: 57  RLPVAAQPKEAAVQSGAGD-------YLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHA 109
           R P+  + + AA +S  G        +L GI R R+LYC  G  FHLQ LPDG + G   
Sbjct: 33  RPPLLGERRSAAERSARGGPGAAQLAHLHGILRRRQLYCRTG--FHLQILPDGSVQGTRQ 90

Query: 110 D-TRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNA 168
           D +   +LE   V  G+VSI GV S  ++ M+ KG+LYGS   T EC F+E    N YN 
Sbjct: 91  DHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNT 150

Query: 169 YES--YKYPG----MFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           Y S  YK+       F+AL+K+G  + G R     K THFLPR
Sbjct: 151 YSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPR 193


>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
          Length = 288

 Score =  102 bits (254), Expect = 2e-22
 Identities = 71/184 (38%), Positives = 94/184 (51%), Gaps = 11/184 (5%)

Query: 25  GRGGAAAPTAPNGTLEAELERRWES--LVALSLARLPVAAQPKEAAVQSGAGDYLLG-IK 81
           GRG      AP     A   R   +  + A S+  LP  A P++     G+G +  G  K
Sbjct: 107 GRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLP--ALPEDG----GSGAFPPGHFK 160

Query: 82  RLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSL-LELSPVERGVVSIFGVASRFFVAMS 140
             +RLYC  G GF L+  PDGR+ G    +   + L+L   ERGVVSI GV +  ++AM 
Sbjct: 161 DPKRLYCKNG-GFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMK 219

Query: 141 SKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIALSKNGKTKKGNRVSPTMKVT 200
             G+L  S   TDEC F E L  NNYN Y S KY   ++AL + G+ K G++  P  K  
Sbjct: 220 EDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAI 279

Query: 201 HFLP 204
            FLP
Sbjct: 280 LFLP 283


>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
          Length = 207

 Score = 97.8 bits (242), Expect = 6e-21
 Identities = 64/171 (37%), Positives = 91/171 (53%), Gaps = 21/171 (12%)

Query: 54  SLARLPVAAQPK---------EAAVQSGAGD---YLLGIKRLRRLYCNVGIGFHLQALPD 101
           SL  +P+A  P          E  +Q G+     +L GI R R+LYC  G  FHL+  P+
Sbjct: 21  SLGNVPLADSPGFLNERLGQIEGKLQRGSPTDFAHLKGILRRRQLYCRTG--FHLEIFPN 78

Query: 102 GRIGGA-HADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEI 160
           G + G  H  +R  +LE   +  G++SI GV S  ++ M+ +G+LYGS   T EC F+E 
Sbjct: 79  GTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYLGMNERGELYGSKKLTRECVFREQ 138

Query: 161 LLPNNYNAYES--YKYPG----MFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
              N YN Y S  YK+       ++AL+K+G  ++G R     K THFLPR
Sbjct: 139 FEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYRTKRHQKFTHFLPR 189


>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
          Length = 170

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 63/167 (37%), Positives = 88/167 (52%), Gaps = 7/167 (4%)

Query: 45  RRWESLVALSLARLPVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRI 104
           R W  L  L LAR P AA    A+    +  +L G  R RRL+ +    F L+  P GR+
Sbjct: 4   RLWLGLAWLLLARAPDAAGTPSASRGPRSYPHLEGDVRWRRLFSSTH--FFLRVDPGGRV 61

Query: 105 GGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLP 163
            G      +DS+LE+  V  GVV I  V+S F+VAM+ +G+LYGS  +T +C F+E +  
Sbjct: 62  QGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEE 121

Query: 164 NNYNAYESYKY----PGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206
           N +N Y S ++      MF+AL + G  + G R        HFLP L
Sbjct: 122 NGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVL 168


>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
          Length = 252

 Score = 92.4 bits (228), Expect = 2e-19
 Identities = 54/128 (42%), Positives = 69/128 (53%), Gaps = 9/128 (7%)

Query: 85  RLYCNVGIGFHLQALPDGRIGGAHAD-TRDSLLELSPVERGVVSIFGVASRFFVAMSSKG 143
           RLYC  G  ++LQ  PDG + G   D T  +L  L PV   VV+I GV +  ++AM+ +G
Sbjct: 79  RLYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 136

Query: 144 KLYGSPFFTDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTM 197
            LY S  FT EC FKE +  N Y  Y S  Y         F+ L+K G+  KGNRV  T 
Sbjct: 137 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 196

Query: 198 KVTHFLPR 205
              HFLP+
Sbjct: 197 PAAHFLPK 204


>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
          Length = 247

 Score = 92.4 bits (228), Expect = 2e-19
 Identities = 54/128 (42%), Positives = 69/128 (53%), Gaps = 9/128 (7%)

Query: 85  RLYCNVGIGFHLQALPDGRIGGAHAD-TRDSLLELSPVERGVVSIFGVASRFFVAMSSKG 143
           RLYC  G  ++LQ  PDG + G   D T  +L  L PV   VV+I GV +  ++AM+ +G
Sbjct: 74  RLYCRQG--YYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLYIAMNGEG 131

Query: 144 KLYGSPFFTDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTM 197
            LY S  FT EC FKE +  N Y  Y S  Y         F+ L+K G+  KGNRV  T 
Sbjct: 132 YLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKGNRVKKTK 191

Query: 198 KVTHFLPR 205
              HFLP+
Sbjct: 192 PAAHFLPK 199


>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
          Length = 225

 Score = 88.6 bits (218), Expect = 3e-18
 Identities = 63/164 (38%), Positives = 81/164 (49%), Gaps = 14/164 (8%)

Query: 50  LVALSLARLPVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHA 109
           L+ LS  RL      + A    G    L GI  + +L+C  G  F+LQA PDG I G   
Sbjct: 44  LILLSKVRL---CGGRPARPDRGPEPQLKGI--VTKLFCRQG--FYLQANPDGSIQGTPE 96

Query: 110 DTRD-SLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNA 168
           DT   +   L PV   VV+I       ++AM+++G LY SP FT EC FKE +  N Y  
Sbjct: 97  DTSSFTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVL 156

Query: 169 YESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206
           Y S  Y         ++ L K G+  KGNRV  T    HFLP+L
Sbjct: 157 YASALYRQRRSGRAWYLGLDKEGQVMKGNRVKKTKAAAHFLPKL 200


>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
          Length = 239

 Score = 87.8 bits (216), Expect = 6e-18
 Identities = 53/164 (32%), Positives = 89/164 (54%), Gaps = 18/164 (10%)

Query: 59  PVAAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLEL 118
           P A   ++A  + G  ++L G  R R+LYC     +HLQ  P GR+ G+  ++  S+LE+
Sbjct: 21  PGARLRRDAGGRGGVYEHLGGAPRRRKLYC--ATKYHLQLHPSGRVNGSLENSAYSILEI 78

Query: 119 SPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKY---- 174
           + VE G+V+I G+ S  ++AM+ +G+LY S  ++ EC F E +    YN Y S  Y    
Sbjct: 79  TAVEVGIVAIRGLFSGRYLAMNKRGRLYASEHYSAECEFVERIHELGYNTYASRLYRTVS 138

Query: 175 --PG----------MFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206
             PG           +++++  G+ ++G +   T K + FLPR+
Sbjct: 139 STPGARRQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRV 182


>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
          Length = 226

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 49/120 (40%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+HLQ   DG I G    D+  +L  L PV   VV+I GV ++ ++AM+S+G LY S  F
Sbjct: 59  GYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF 118

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y       G ++ L+K G+  KGN V       HFLP+
Sbjct: 119 TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 178


>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
          Length = 226

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 49/120 (40%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+HLQ   DG I G    D+  +L  L PV   VV+I GV ++ ++AM+S+G LY S  F
Sbjct: 59  GYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF 118

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y       G ++ L+K G+  KGN V       HFLP+
Sbjct: 119 TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 178


>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
          Length = 255

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 49/120 (40%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+HLQ   DG I G    D+  +L  L PV   VV+I GV ++ ++AM+S+G LY S  F
Sbjct: 88  GYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF 147

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y       G ++ L+K G+  KGN V       HFLP+
Sbjct: 148 TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 207


>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
          Length = 199

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 49/120 (40%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+HLQ   DG I G    D+  +L  L PV   VV+I GV ++ ++AM+S+G LY S  F
Sbjct: 32  GYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF 91

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y       G ++ L+K G+  KGN V       HFLP+
Sbjct: 92  TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 151


>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
          Length = 245

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 49/120 (40%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+HLQ   DG I G    D+  +L  L PV   VV+I GV ++ ++AM+S+G LY S  F
Sbjct: 78  GYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF 137

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y       G ++ L+K G+  KGN V       HFLP+
Sbjct: 138 TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 197


>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
          Length = 192

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 49/120 (40%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAH-ADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+HLQ   DG I G    D+  +L  L PV   VV+I GV ++ ++AM+S+G LY S  F
Sbjct: 25  GYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF 84

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y       G ++ L+K G+  KGN V       HFLP+
Sbjct: 85  TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 144


>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
          Length = 181

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 50/120 (41%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAHADTRD-SLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+ LQ  PDG I G   +  D +L  L PV   VV+I GV +  +VAM+ +G LY S  F
Sbjct: 20  GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 79

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y         F+ L+K G+  KGNRV  T   +HF+P+
Sbjct: 80  TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPK 139


>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
          Length = 243

 Score = 85.5 bits (210), Expect = 3e-17
 Identities = 50/120 (41%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 93  GFHLQALPDGRIGGAHADTRD-SLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151
           G+ LQ  PDG I G   +  D +L  L PV   VV+I GV +  +VAM+ +G LY S  F
Sbjct: 82  GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 141

Query: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205
           T EC FKE +  N Y  Y S  Y         F+ L+K G+  KGNRV  T   +HF+P+
Sbjct: 142 TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPK 201


>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
          Length = 194

 Score = 84.3 bits (207), Expect = 6e-17
 Identities = 48/136 (35%), Positives = 78/136 (57%), Gaps = 8/136 (5%)

Query: 75  DYLLGIK-RLRRLYCNVGIGFHLQALPDGRIGGAHADTRD-SLLELSPVERGVVSIFGVA 132
           DY+ G   R+RRL+C     ++L+    G++ G      + +++E+  V  G+V+I GV 
Sbjct: 57  DYMEGGDIRVRRLFCRTQ--WYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVE 114

Query: 133 SRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYP----GMFIALSKNGKTK 188
           S F++AM+ +GKLY      ++C FKE++L N+YN Y S K+      MF+AL++ G   
Sbjct: 115 SEFYLAMNKEGKLYAKKECNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIPV 174

Query: 189 KGNRVSPTMKVTHFLP 204
           +G +     K  HFLP
Sbjct: 175 RGKKTKKEQKTAHFLP 190


>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
          Length = 208

 Score = 78.6 bits (192), Expect = 4e-15
 Identities = 46/148 (31%), Positives = 79/148 (53%), Gaps = 7/148 (4%)

Query: 62  AQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRD-SLLELSP 120
           + P  A     + ++L G  R R+L+      + L+   +G++ G   +    S+LE++ 
Sbjct: 58  SSPSSAGRHVRSYNHLQGDVRWRKLFSFTK--YFLKIEKNGKVSGTKKENCPYSILEITS 115

Query: 121 VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYP----G 176
           VE GVV++  + S +++AM+ KGKLYGS  F ++C  KE +  N YN Y S+ +      
Sbjct: 116 VEIGVVAVKAINSNYYLAMNKKGKLYGSKEFNNDCKLKERIEENGYNTYASFNWQHNGRQ 175

Query: 177 MFIALSKNGKTKKGNRVSPTMKVTHFLP 204
           M++AL+  G  ++G +        HFLP
Sbjct: 176 MYVALNGKGAPRRGQKTRRKNTSAHFLP 203


>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 48/127 (37%), Positives = 65/127 (51%), Gaps = 4/127 (3%)

Query: 81  KRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSL-LELSPVERGVVSIFGVASRFFVAM 139
           K+ + LYC+ G G  L+ LPDG + G    +   + L+LS    G V I    +  ++AM
Sbjct: 24  KKPKLLYCSNG-GHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAM 82

Query: 140 SSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKY--PGMFIALSKNGKTKKGNRVSPTM 197
            + G LYGS    +EC F E L  N+YN Y S K+     F+ L KNG  K+G R     
Sbjct: 83  DTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQ 142

Query: 198 KVTHFLP 204
           K   FLP
Sbjct: 143 KAILFLP 149


>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
           [Homo sapiens]
          Length = 155

 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 48/127 (37%), Positives = 65/127 (51%), Gaps = 4/127 (3%)

Query: 81  KRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSL-LELSPVERGVVSIFGVASRFFVAM 139
           K+ + LYC+ G G  L+ LPDG + G    +   + L+LS    G V I    +  ++AM
Sbjct: 24  KKPKLLYCSNG-GHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAM 82

Query: 140 SSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKY--PGMFIALSKNGKTKKGNRVSPTM 197
            + G LYGS    +EC F E L  N+YN Y S K+     F+ L KNG  K+G R     
Sbjct: 83  DTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQ 142

Query: 198 KVTHFLP 204
           K   FLP
Sbjct: 143 KAILFLP 149


>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 48/127 (37%), Positives = 65/127 (51%), Gaps = 4/127 (3%)

Query: 81  KRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSL-LELSPVERGVVSIFGVASRFFVAM 139
           K+ + LYC+ G G  L+ LPDG + G    +   + L+LS    G V I    +  ++AM
Sbjct: 24  KKPKLLYCSNG-GHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAM 82

Query: 140 SSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKY--PGMFIALSKNGKTKKGNRVSPTM 197
            + G LYGS    +EC F E L  N+YN Y S K+     F+ L KNG  K+G R     
Sbjct: 83  DTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQ 142

Query: 198 KVTHFLP 204
           K   FLP
Sbjct: 143 KAILFLP 149


>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 72.0 bits (175), Expect = 3e-13
 Identities = 48/127 (37%), Positives = 65/127 (51%), Gaps = 4/127 (3%)

Query: 81  KRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSL-LELSPVERGVVSIFGVASRFFVAM 139
           K+ + LYC+ G G  L+ LPDG + G    +   + L+LS    G V I    +  ++AM
Sbjct: 24  KKPKLLYCSNG-GHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAM 82

Query: 140 SSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKY--PGMFIALSKNGKTKKGNRVSPTM 197
            + G LYGS    +EC F E L  N+YN Y S K+     F+ L KNG  K+G R     
Sbjct: 83  DTDGLLYGSQTPNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQ 142

Query: 198 KVTHFLP 204
           K   FLP
Sbjct: 143 KAILFLP 149


>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
          Length = 207

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 45/128 (35%), Positives = 63/128 (49%), Gaps = 7/128 (5%)

Query: 82  RLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLEL---SPVERGVVSIFGVASRFFVA 138
           RL +LY     G H+Q L  GR   A  +  D   +L   +      V I G  + F++ 
Sbjct: 53  RLYQLYSRTS-GKHIQVL--GRRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLC 109

Query: 139 MSSKGKLYGSPFFTD-ECTFKEILLPNNYNAYESYKYPGMFIALSKNGKTKKGNRVSPTM 197
           M+ KGKL G P  T  EC F E +L NNY A  S KY G ++  +K G+ +KG +     
Sbjct: 110 MNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQ 169

Query: 198 KVTHFLPR 205
           +  HF+ R
Sbjct: 170 QDVHFMKR 177


>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
          Length = 209

 Score = 65.9 bits (159), Expect = 2e-11
 Identities = 33/78 (42%), Positives = 48/78 (61%), Gaps = 1/78 (1%)

Query: 95  HLQALPDGRIGGAHADTRDSLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDE 154
           HL+   DG +GGA   + +SLL+L  ++ GV+ I GV +  F+     G LYGS  F  E
Sbjct: 60  HLEIREDGTVGGAADQSPESLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119

Query: 155 -CTFKEILLPNNYNAYES 171
            C+F+E+LL + YN Y+S
Sbjct: 120 ACSFRELLLEDGYNVYQS 137


>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
           sapiens]
          Length = 204

 Score = 63.9 bits (154), Expect = 9e-11
 Identities = 52/164 (31%), Positives = 80/164 (48%), Gaps = 9/164 (5%)

Query: 49  SLVALSLARLPVAAQPKEAAVQSGAGDYLLG-IKRLRRLYCNVGIGFHLQALPDGRIGGA 107
           +L  L L  L +  Q +    QS   D L   + R  +LY     G H+Q L + RI  A
Sbjct: 7   ALSCLLLHLLVLCLQAQHVREQSLVTDQLSRRLIRTYQLYSRTS-GKHVQVLANKRIN-A 64

Query: 108 HADTRDSLLELSPVERGV----VSIFGVASRFFVAMSSKGKLYG-SPFFTDECTFKEILL 162
            A+  D   +L  VE       V + G  +  ++ M+ KGKL   S     +C F EI+L
Sbjct: 65  MAEDGDPFAKLI-VETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVL 123

Query: 163 PNNYNAYESYKYPGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206
            NNY A ++ KY G ++A ++ G+ +KG++     +  HF+ RL
Sbjct: 124 ENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRL 167


>gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo
           sapiens]
          Length = 233

 Score = 63.5 bits (153), Expect = 1e-10
 Identities = 63/212 (29%), Positives = 92/212 (43%), Gaps = 22/212 (10%)

Query: 1   MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV 60
           M  P +A   LL  +L+  L    G G   A           L R   SL      R P 
Sbjct: 1   MGSPRSALSCLLLHLLVLCLQAQEGPGRGPA-----------LGRELASL--FRAGREPQ 47

Query: 61  AAQPKEAAVQSGAGDYLLG-IKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELS 119
               +    QS   D L   + R  +LY     G H+Q L + RI  A A+  D   +L 
Sbjct: 48  GVSQQHVREQSLVTDQLSRRLIRTYQLYSRTS-GKHVQVLANKRIN-AMAEDGDPFAKLI 105

Query: 120 PVERGV----VSIFGVASRFFVAMSSKGKLYG-SPFFTDECTFKEILLPNNYNAYESYKY 174
            VE       V + G  +  ++ M+ KGKL   S     +C F EI+L NNY A ++ KY
Sbjct: 106 -VETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKY 164

Query: 175 PGMFIALSKNGKTKKGNRVSPTMKVTHFLPRL 206
            G ++A ++ G+ +KG++     +  HF+ RL
Sbjct: 165 EGWYMAFTRKGRPRKGSKTRQHQREVHFMKRL 196


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,170,004
Number of Sequences: 37866
Number of extensions: 355975
Number of successful extensions: 1086
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 989
Number of HSP's gapped (non-prelim): 70
length of query: 206
length of database: 18,247,518
effective HSP length: 97
effective length of query: 109
effective length of database: 14,574,516
effective search space: 1588622244
effective search space used: 1588622244
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.