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Search of human proteins with 4503693
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
(216 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens] 442 e-124
gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo ... 254 3e-68
gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo... 242 2e-64
gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo... 238 2e-63
gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo... 237 6e-63
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens] 219 1e-57
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens] 72 5e-13
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens] 63 2e-10
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens] 62 5e-10
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens] 61 8e-10
gi|9789947 fibroblast growth factor 20 [Homo sapiens] 60 2e-09
gi|4503691 fibroblast growth factor 16 [Homo sapiens] 60 2e-09
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens] 56 3e-08
gi|153285461 fibroblast growth factor 2 [Homo sapiens] 51 9e-07
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo... 49 2e-06
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens] 49 2e-06
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens] 47 9e-06
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens] 47 9e-06
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens] 47 9e-06
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr... 47 2e-05
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot... 47 2e-05
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr... 47 2e-05
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr... 47 2e-05
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens] 46 2e-05
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens] 46 2e-05
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens] 46 2e-05
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens] 46 3e-05
gi|4758362 fibroblast growth factor 11 [Homo sapiens] 46 3e-05
gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens] 43 2e-04
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens] 43 2e-04
>gi|4503693 fibroblast growth factor 17 precursor [Homo sapiens]
Length = 216
Score = 442 bits (1136), Expect = e-124
Identities = 216/216 (100%), Positives = 216/216 (100%)
Query: 1 MGAARLLPNLTLCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSR 60
MGAARLLPNLTLCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSR
Sbjct: 1 MGAARLLPNLTLCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSR 60
Query: 61 TSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKP 120
TSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKP
Sbjct: 61 TSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKP 120
Query: 121 SGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQ 180
SGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQ
Sbjct: 121 SGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQ 180
Query: 181 GQLPFPNHAEKQKQFEFVGSAPTRRTKRTRRPQPLT 216
GQLPFPNHAEKQKQFEFVGSAPTRRTKRTRRPQPLT
Sbjct: 181 GQLPFPNHAEKQKQFEFVGSAPTRRTKRTRRPQPLT 216
>gi|5174439 fibroblast growth factor 8 isoform B precursor [Homo
sapiens]
Length = 215
Score = 254 bits (650), Expect = 3e-68
Identities = 131/208 (62%), Positives = 160/208 (76%), Gaps = 9/208 (4%)
Query: 12 LCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQV-TG 70
L L LL+LC Q Q SPNF Q+VR+Q +TDQLSRR IR YQLYSRTSGKHVQV
Sbjct: 11 LLLHLLVLCLQAQVTVQSSPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLAN 70
Query: 71 RRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFT 130
+RI+A AEDG+ FAKLIVETDTFGSRVR++GAE+ YICMNK+GKLI K +GK KDCVFT
Sbjct: 71 KRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFT 130
Query: 131 EIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAE 190
EIVLENNYTA QNA++EGW+MAFTR+GRPR+ S++RQ+QRE HF+KRL +G + E
Sbjct: 131 EIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGH----HTTE 186
Query: 191 KQKQFEFVGSAP----TRRTKRTRRPQP 214
+ +FEF+ P R ++RT P+P
Sbjct: 187 QSLRFEFLNYPPFTRSLRGSQRTWAPEP 214
>gi|15147346 fibroblast growth factor 8 isoform F precursor [Homo
sapiens]
Length = 244
Score = 242 bits (618), Expect = 2e-64
Identities = 123/190 (64%), Positives = 151/190 (79%), Gaps = 9/190 (4%)
Query: 30 SPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQV-TGRRISATAEDGNKFAKLIV 88
SPNF Q+VR+Q +TDQLSRR IR YQLYSRTSGKHVQV +RI+A AEDG+ FAKLIV
Sbjct: 58 SPNFTQHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIV 117
Query: 89 ETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEG 148
ETDTFGSRVR++GAE+ YICMNK+GKLI K +GK KDCVFTEIVLENNYTA QNA++EG
Sbjct: 118 ETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEG 177
Query: 149 WFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAEKQKQFEFVGSAP----TR 204
W+MAFTR+GRPR+ S++RQ+QRE HF+KRL +G + E+ +FEF+ P R
Sbjct: 178 WYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGH----HTTEQSLRFEFLNYPPFTRSLR 233
Query: 205 RTKRTRRPQP 214
++RT P+P
Sbjct: 234 GSQRTWAPEP 243
>gi|15147350 fibroblast growth factor 8 isoform A precursor [Homo
sapiens]
Length = 204
Score = 238 bits (608), Expect = 2e-63
Identities = 126/208 (60%), Positives = 155/208 (74%), Gaps = 20/208 (9%)
Query: 12 LCLQLLILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQV-TG 70
L L LL+LC Q Q +VR+Q +TDQLSRR IR YQLYSRTSGKHVQV
Sbjct: 11 LLLHLLVLCLQAQ-----------HVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLAN 59
Query: 71 RRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFT 130
+RI+A AEDG+ FAKLIVETDTFGSRVR++GAE+ YICMNK+GKLI K +GK KDCVFT
Sbjct: 60 KRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFT 119
Query: 131 EIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAE 190
EIVLENNYTA QNA++EGW+MAFTR+GRPR+ S++RQ+QRE HF+KRL +G + E
Sbjct: 120 EIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGH----HTTE 175
Query: 191 KQKQFEFVGSAP----TRRTKRTRRPQP 214
+ +FEF+ P R ++RT P+P
Sbjct: 176 QSLRFEFLNYPPFTRSLRGSQRTWAPEP 203
>gi|15147348 fibroblast growth factor 8 isoform E precursor [Homo
sapiens]
Length = 233
Score = 237 bits (604), Expect = 6e-63
Identities = 128/226 (56%), Positives = 157/226 (69%), Gaps = 27/226 (11%)
Query: 12 LCLQLLILCCQTQ------------------GENHPSPNFNQYVRDQGAMTDQLSRRQIR 53
L L LL+LC Q Q P Q+VR+Q +TDQLSRR IR
Sbjct: 11 LLLHLLVLCLQAQEGPGRGPALGRELASLFRAGREPQGVSQQHVREQSLVTDQLSRRLIR 70
Query: 54 EYQLYSRTSGKHVQV-TGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNK 112
YQLYSRTSGKHVQV +RI+A AEDG+ FAKLIVETDTFGSRVR++GAE+ YICMNK
Sbjct: 71 TYQLYSRTSGKHVQVLANKRINAMAEDGDPFAKLIVETDTFGSRVRVRGAETGLYICMNK 130
Query: 113 RGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREA 172
+GKLI K +GK KDCVFTEIVLENNYTA QNA++EGW+MAFTR+GRPR+ S++RQ+QRE
Sbjct: 131 KGKLIAKSNGKGKDCVFTEIVLENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREV 190
Query: 173 HFIKRLYQGQLPFPNHAEKQKQFEFVGSAP----TRRTKRTRRPQP 214
HF+KRL +G + E+ +FEF+ P R ++RT P+P
Sbjct: 191 HFMKRLPRGH----HTTEQSLRFEFLNYPPFTRSLRGSQRTWAPEP 232
>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
Length = 207
Score = 219 bits (559), Expect = 1e-57
Identities = 110/204 (53%), Positives = 149/204 (73%), Gaps = 12/204 (5%)
Query: 12 LCLQLLILCCQTQG-ENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTG 70
LCL L+LC Q Q + +F +V +Q D +SR+Q+R YQLYSRTSGKH+QV G
Sbjct: 11 LCLHFLLLCFQVQVLVAEENVDFRIHVENQTRARDDVSRKQLRLYQLYSRTSGKHIQVLG 70
Query: 71 RRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFT 130
RRISA EDG+K+A+L+VETDTFGS+VRIKG E+E Y+CMN++GKL+GKP G SK+CVF
Sbjct: 71 RRISARGEDGDKYAQLLVETDTFGSQVRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFI 130
Query: 131 EIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQGQLPFPNHAE 190
E VLENNYTA +A++ GW++ FT++GRPR+ ++R+NQ++ HF+KR +GQ E
Sbjct: 131 EKVLENNYTALMSAKYSGWYVGFTKKGRPRKGPKTRENQQDVHFMKRYPKGQ------PE 184
Query: 191 KQKQFEFVGSAPTRRTKRTRRPQP 214
QK F++ T TKR+RR +P
Sbjct: 185 LQKPFKY-----TTVTKRSRRIRP 203
>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
Length = 194
Score = 71.6 bits (174), Expect = 5e-13
Identities = 46/136 (33%), Positives = 77/136 (56%), Gaps = 8/136 (5%)
Query: 45 DQLSRRQIREYQLYSRTSGKHVQVTGR-RISATAEDGNKFAKLIVETDTFGSRVRIKGAE 103
D + IR +L+ RT ++++ R ++ T E N + + + T G V IKG E
Sbjct: 57 DYMEGGDIRVRRLFCRTQW-YLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGI-VAIKGVE 114
Query: 104 SEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNAR--HEG--WFMAFTRQGRP 159
SE Y+ MNK GKL K ++DC F E++LEN+Y + +A+ H G F+A ++G P
Sbjct: 115 SEFYLAMNKEGKLYAKKE-CNEDCNFKELILENHYNTYASAKWTHNGGEMFVALNQKGIP 173
Query: 160 RQASRSRQNQREAHFI 175
+ ++++ Q+ AHF+
Sbjct: 174 VRGKKTKKEQKTAHFL 189
>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
Length = 208
Score = 63.2 bits (152), Expect = 2e-10
Identities = 41/128 (32%), Positives = 71/128 (55%), Gaps = 5/128 (3%)
Query: 53 REYQLYSRTS-GKHVQVT-GRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICM 110
R+ +LY G H+QV RIS T E+ N ++ L + T G V + G S ++ M
Sbjct: 84 RQRRLYCNVGIGFHLQVLPDGRISGTHEE-NPYSLLEISTVERGV-VSLFGVRSALFVAM 141
Query: 111 NKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQR 170
N +G+L PS + ++C F E +L NNY A+++ ++G ++A ++ GR ++ S+
Sbjct: 142 NSKGRLYATPSFQ-EECKFRETLLPNNYNAYESDLYQGTYIALSKYGRVKRGSKVSPIMT 200
Query: 171 EAHFIKRL 178
HF+ R+
Sbjct: 201 VTHFLPRI 208
>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
Length = 206
Score = 61.6 bits (148), Expect = 5e-10
Identities = 28/82 (34%), Positives = 49/82 (59%), Gaps = 1/82 (1%)
Query: 97 VRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQ 156
V I G S ++ M+ +GKL G P + +C F EI+L NNY A+++ ++ G F+A ++
Sbjct: 126 VSIFGVASRFFVAMSSKGKLYGSPFF-TDECTFKEILLPNNYNAYESYKYPGMFIALSKN 184
Query: 157 GRPRQASRSRQNQREAHFIKRL 178
G+ ++ +R + HF+ RL
Sbjct: 185 GKTKKGNRVSPTMKVTHFLPRL 206
>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
Length = 208
Score = 60.8 bits (146), Expect = 8e-10
Identities = 40/133 (30%), Positives = 73/133 (54%), Gaps = 10/133 (7%)
Query: 52 IREYQLYSRTSGKHVQV-TGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICM 110
+R QLY RT G H+++ I T +D ++F L + G V I+G +S Y+ M
Sbjct: 61 LRRRQLYCRT-GFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGL-VSIRGVDSGLYLGM 118
Query: 111 NKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEG------WFMAFTRQGRPRQASR 164
N++G+L G +++CVF E EN Y + + ++ +++A + G PR+ +R
Sbjct: 119 NEKGELYGSEK-LTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGTR 177
Query: 165 SRQNQREAHFIKR 177
++++Q+ HF+ R
Sbjct: 178 TKRHQKFTHFLPR 190
>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
Length = 211
Score = 59.7 bits (143), Expect = 2e-09
Identities = 42/133 (31%), Positives = 69/133 (51%), Gaps = 10/133 (7%)
Query: 52 IREYQLYSRTSGKHVQVT-GRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICM 110
+R QLY RT G H+Q+ + T +D + F L + G V I+G +S Y+ M
Sbjct: 64 LRRRQLYCRT-GFHLQILPDGSVQGTRQDHSLFGILEFISVAVGL-VSIRGVDSGLYLGM 121
Query: 111 NKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEG------WFMAFTRQGRPRQASR 164
N +G+L G S +C+F E EN Y + + ++ +F+A + G PR +R
Sbjct: 122 NDKGELYGSEKLTS-ECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGAR 180
Query: 165 SRQNQREAHFIKR 177
S+++Q+ HF+ R
Sbjct: 181 SKRHQKFTHFLPR 193
>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
Length = 207
Score = 59.7 bits (143), Expect = 2e-09
Identities = 39/133 (29%), Positives = 71/133 (53%), Gaps = 10/133 (7%)
Query: 52 IREYQLYSRTSGKHVQV-TGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICM 110
+R QLY RT G H+++ + T D ++F L + G + I+G +S Y+ M
Sbjct: 60 LRRRQLYCRT-GFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGL-ISIRGVDSGLYLGM 117
Query: 111 NKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEG------WFMAFTRQGRPRQASR 164
N+RG+L G +++CVF E EN Y + + ++ +++A + G PR+ R
Sbjct: 118 NERGELYGSKK-LTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGYR 176
Query: 165 SRQNQREAHFIKR 177
++++Q+ HF+ R
Sbjct: 177 TKRHQKFTHFLPR 189
>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
Length = 208
Score = 55.8 bits (133), Expect = 3e-08
Identities = 48/194 (24%), Positives = 84/194 (43%), Gaps = 32/194 (16%)
Query: 7 LPNLTLCLQLLI-------LCCQTQGENHPSP--------------NFNQYVRDQGAMTD 45
LP C LL+ + CQ G++ SP + ++VR +
Sbjct: 16 LPGCCCCCFLLLFLVSSVPVTCQALGQDMVSPEATNSSSSSFSSPSSAGRHVRSYNHLQG 75
Query: 46 QLSRRQIREYQLYSRTSGKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESE 105
+ R++ + Y K+ +V+G T ++ ++ L + + G V +K S
Sbjct: 76 DVRWRKLFSFTKYFLKIEKNGKVSG-----TKKENCPYSILEITSVEIGV-VAVKAINSN 129
Query: 106 KYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQ--NARHEG--WFMAFTRQGRPRQ 161
Y+ MNK+GKL G + DC E + EN Y + N +H G ++A +G PR+
Sbjct: 130 YYLAMNKKGKLYGSKE-FNNDCKLKERIEENGYNTYASFNWQHNGRQMYVALNGKGAPRR 188
Query: 162 ASRSRQNQREAHFI 175
++R+ AHF+
Sbjct: 189 GQKTRRKNTSAHFL 202
>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
Length = 288
Score = 50.8 bits (120), Expect = 9e-07
Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 3/121 (2%)
Query: 56 QLYSRTSGKHVQV-TGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRG 114
+LY + G +++ R+ E + KL ++ + G V IKG + +Y+ M + G
Sbjct: 164 RLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGV-VSIKGVCANRYLAMKEDG 222
Query: 115 KLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQGRPRQASRSRQNQREAHF 174
+L+ + +C F E + NNY +++ ++ W++A R G+ + S++ Q+ F
Sbjct: 223 RLLASKC-VTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILF 281
Query: 175 I 175
+
Sbjct: 282 L 282
>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
sapiens]
Length = 268
Score = 49.3 bits (116), Expect = 2e-06
Identities = 40/142 (28%), Positives = 67/142 (47%), Gaps = 13/142 (9%)
Query: 53 REYQLYSRTS-GKHVQVTGRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMN 111
R LY R G H+Q+ + + N + L + + G V I+G S K++ M+
Sbjct: 87 RTGSLYCRVGIGFHLQIYPDGKVNGSHEANMLSVLEIFAVSQGI-VGIRGVFSNKFLAMS 145
Query: 112 KRGKLIGKPSGK-SKDCVFTEIVLENNYTAFQNARH------EGWFMAFTRQGRPRQ--A 162
K+GKL S K + DC F E EN+Y + +A H W++A ++G+ ++ +
Sbjct: 146 KKGKL--HASAKFTDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCS 203
Query: 163 SRSRQNQREAHFIKRLYQGQLP 184
R + HF+ R Q + P
Sbjct: 204 PRVKPQHISTHFLPRFKQSEQP 225
>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
Length = 170
Score = 49.3 bits (116), Expect = 2e-06
Identities = 29/83 (34%), Positives = 43/83 (51%), Gaps = 5/83 (6%)
Query: 97 VRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARH----EGWFMA 152
V IK S Y+ MN+RG+L G + DC F E + EN + + + R + F+A
Sbjct: 84 VVIKAVSSGFYVAMNRRGRLYGSRL-YTVDCRFRERIEENGHNTYASQRWRRRGQPMFLA 142
Query: 153 FTRQGRPRQASRSRQNQREAHFI 175
R+G PR R+R+ AHF+
Sbjct: 143 LDRRGGPRPGGRTRRYHLSAHFL 165
>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 47.4 bits (111), Expect = 9e-06
Identities = 40/168 (23%), Positives = 73/168 (43%), Gaps = 23/168 (13%)
Query: 18 ILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGR-RISAT 76
I CC + +H + + +G +T +LYSR G H+Q+ I T
Sbjct: 26 IFCCPLKQVHHKENTEPEEPQLKGIVT-----------KLYSR-QGYHLQLQADGTIDGT 73
Query: 77 AEDGNKFAKLIVETDTFGSRV-RIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLE 135
++ + + + G RV I+G +++ Y+ MN G L + +C F E V E
Sbjct: 74 KDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF-TPECKFKESVFE 130
Query: 136 NNYTAF------QNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKR 177
N Y + Q GW++ ++G + + ++N+ AHF+ +
Sbjct: 131 NYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 178
>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
Length = 226
Score = 47.4 bits (111), Expect = 9e-06
Identities = 40/168 (23%), Positives = 73/168 (43%), Gaps = 23/168 (13%)
Query: 18 ILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGR-RISAT 76
I CC + +H + + +G +T +LYSR G H+Q+ I T
Sbjct: 26 IFCCPLKQVHHKENTEPEEPQLKGIVT-----------KLYSR-QGYHLQLQADGTIDGT 73
Query: 77 AEDGNKFAKLIVETDTFGSRV-RIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLE 135
++ + + + G RV I+G +++ Y+ MN G L + +C F E V E
Sbjct: 74 KDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF-TPECKFKESVFE 130
Query: 136 NNYTAF------QNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKR 177
N Y + Q GW++ ++G + + ++N+ AHF+ +
Sbjct: 131 NYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 178
>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
Length = 255
Score = 47.4 bits (111), Expect = 9e-06
Identities = 40/168 (23%), Positives = 73/168 (43%), Gaps = 23/168 (13%)
Query: 18 ILCCQTQGENHPSPNFNQYVRDQGAMTDQLSRRQIREYQLYSRTSGKHVQVTGR-RISAT 76
I CC + +H + + +G +T +LYSR G H+Q+ I T
Sbjct: 55 IFCCPLKQVHHKENTEPEEPQLKGIVT-----------KLYSR-QGYHLQLQADGTIDGT 102
Query: 77 AEDGNKFAKLIVETDTFGSRV-RIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLE 135
++ + + + G RV I+G +++ Y+ MN G L + +C F E V E
Sbjct: 103 KDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSEGYLYTSELF-TPECKFKESVFE 159
Query: 136 NNYTAF------QNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKR 177
N Y + Q GW++ ++G + + ++N+ AHF+ +
Sbjct: 160 NYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKKNKPAAHFLPK 207
>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 46.6 bits (109), Expect = 2e-05
Identities = 28/122 (22%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHVQVT-GRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGK 115
LY G +++ + T + ++ +L + ++ G V IK E+ +Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDGL 87
Query: 116 LIGKPSGKSKDCVFTEIVLENNYTAFQNARH--EGWFMAFTRQGRPRQASRSRQNQREAH 173
L G + +++C+F E + EN+Y + + +H + WF+ + G ++ R+ Q+
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FI 175
F+
Sbjct: 147 FL 148
>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
[Homo sapiens]
Length = 155
Score = 46.6 bits (109), Expect = 2e-05
Identities = 28/122 (22%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHVQVT-GRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGK 115
LY G +++ + T + ++ +L + ++ G V IK E+ +Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDGL 87
Query: 116 LIGKPSGKSKDCVFTEIVLENNYTAFQNARH--EGWFMAFTRQGRPRQASRSRQNQREAH 173
L G + +++C+F E + EN+Y + + +H + WF+ + G ++ R+ Q+
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FI 175
F+
Sbjct: 147 FL 148
>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 46.6 bits (109), Expect = 2e-05
Identities = 28/122 (22%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHVQVT-GRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGK 115
LY G +++ + T + ++ +L + ++ G V IK E+ +Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDGL 87
Query: 116 LIGKPSGKSKDCVFTEIVLENNYTAFQNARH--EGWFMAFTRQGRPRQASRSRQNQREAH 173
L G + +++C+F E + EN+Y + + +H + WF+ + G ++ R+ Q+
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FI 175
F+
Sbjct: 147 FL 148
>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
proprotein [Homo sapiens]
Length = 155
Score = 46.6 bits (109), Expect = 2e-05
Identities = 28/122 (22%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 57 LYSRTSGKHVQVT-GRRISATAEDGNKFAKLIVETDTFGSRVRIKGAESEKYICMNKRGK 115
LY G +++ + T + ++ +L + ++ G V IK E+ +Y+ M+ G
Sbjct: 29 LYCSNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGE-VYIKSTETGQYLAMDTDGL 87
Query: 116 LIGKPSGKSKDCVFTEIVLENNYTAFQNARH--EGWFMAFTRQGRPRQASRSRQNQREAH 173
L G + +++C+F E + EN+Y + + +H + WF+ + G ++ R+ Q+
Sbjct: 88 LYGSQT-PNEECLFLERLEENHYNTYISKKHAEKNWFVGLKKNGSCKRGPRTHYGQKAIL 146
Query: 174 FI 175
F+
Sbjct: 147 FL 148
>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
Length = 199
Score = 46.2 bits (108), Expect = 2e-05
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 12/130 (9%)
Query: 56 QLYSRTSGKHVQVTGR-RISATAEDGNKFAKLIVETDTFGSRV-RIKGAESEKYICMNKR 113
+LYSR G H+Q+ I T ++ + + + G RV I+G +++ Y+ MN
Sbjct: 26 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 82
Query: 114 GKLIGKPSGKSKDCVFTEIVLENNYTAF------QNARHEGWFMAFTRQGRPRQASRSRQ 167
G L + +C F E V EN Y + Q GW++ ++G + + ++
Sbjct: 83 GYLYTSELF-TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 141
Query: 168 NQREAHFIKR 177
N+ AHF+ +
Sbjct: 142 NKPAAHFLPK 151
>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
Length = 245
Score = 46.2 bits (108), Expect = 2e-05
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 12/130 (9%)
Query: 56 QLYSRTSGKHVQVTGR-RISATAEDGNKFAKLIVETDTFGSRV-RIKGAESEKYICMNKR 113
+LYSR G H+Q+ I T ++ + + + G RV I+G +++ Y+ MN
Sbjct: 72 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 128
Query: 114 GKLIGKPSGKSKDCVFTEIVLENNYTAF------QNARHEGWFMAFTRQGRPRQASRSRQ 167
G L + +C F E V EN Y + Q GW++ ++G + + ++
Sbjct: 129 GYLYTSELF-TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 187
Query: 168 NQREAHFIKR 177
N+ AHF+ +
Sbjct: 188 NKPAAHFLPK 197
>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
Length = 192
Score = 46.2 bits (108), Expect = 2e-05
Identities = 34/130 (26%), Positives = 61/130 (46%), Gaps = 12/130 (9%)
Query: 56 QLYSRTSGKHVQVTGR-RISATAEDGNKFAKLIVETDTFGSRV-RIKGAESEKYICMNKR 113
+LYSR G H+Q+ I T ++ + + + G RV I+G +++ Y+ MN
Sbjct: 19 KLYSR-QGYHLQLQADGTIDGTKDEDSTYT--LFNLIPVGLRVVAIQGVQTKLYLAMNSE 75
Query: 114 GKLIGKPSGKSKDCVFTEIVLENNYTAF------QNARHEGWFMAFTRQGRPRQASRSRQ 167
G L + +C F E V EN Y + Q GW++ ++G + + ++
Sbjct: 76 GYLYTSELF-TPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKGNHVKK 134
Query: 168 NQREAHFIKR 177
N+ AHF+ +
Sbjct: 135 NKPAAHFLPK 144
>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
Length = 239
Score = 45.8 bits (107), Expect = 3e-05
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 17/98 (17%)
Query: 97 VRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAF--------------- 141
V I+G S +Y+ MNKRG+L S +C F E + E Y +
Sbjct: 86 VAIRGLFSGRYLAMNKRGRLYASEH-YSAECEFVERIHELGYNTYASRLYRTVSSTPGAR 144
Query: 142 -QNARHEGWFMAFTRQGRPRQASRSRQNQREAHFIKRL 178
Q + W+++ +GRPR+ ++R+ Q+ + F+ R+
Sbjct: 145 RQPSAERLWYVSVNGKGRPRRGFKTRRTQKSSLFLPRV 182
>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
Length = 225
Score = 45.8 bits (107), Expect = 3e-05
Identities = 31/115 (26%), Positives = 53/115 (46%), Gaps = 10/115 (8%)
Query: 73 ISATAEDGNKFAKLIVETDTFGSRV-RIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTE 131
I T ED + F G RV I+ A+ Y+ MN G L P + +C F E
Sbjct: 91 IQGTPEDTSSFTHF--NLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTA-ECRFKE 147
Query: 132 IVLENNYTAFQNARHE------GWFMAFTRQGRPRQASRSRQNQREAHFIKRLYQ 180
V EN Y + +A + W++ ++G+ + +R ++ + AHF+ +L +
Sbjct: 148 CVFENYYVLYASALYRQRRSGRAWYLGLDKEGQVMKGNRVKKTKAAAHFLPKLLE 202
>gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]
Length = 216
Score = 42.7 bits (99), Expect = 2e-04
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 97 VRIKGAESEKYICMNKRGKLIGKPSGKSKDCVFTEIVLENNYTAFQNARHEGWFMAFTRQ 156
V IKG S +Y+CM GK+ G +DC F E + + Y +++ +H
Sbjct: 90 VAIKGVHSVRYLCMGADGKMQGLLQYSEEDCAFEEEIRPDGYNVYRSEKHR--LPVSLSS 147
Query: 157 GRPRQASRSRQNQREAHFIKRL 178
+ RQ ++R +HF+ L
Sbjct: 148 AKQRQLYKNRGFLPLSHFLPML 169
>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
Length = 252
Score = 42.7 bits (99), Expect = 2e-04
Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 97 VRIKGAESEKYICMNKRGKLIGKPSGK-SKDCVFTEIVLENNYTAF------QNARHEGW 149
V I+G ++ YI MN G L PS + +C F E V EN Y + Q W
Sbjct: 119 VAIQGVKTGLYIAMNGEGYLY--PSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAW 176
Query: 150 FMAFTRQGRPRQASRSRQNQREAHFIKR 177
F+ ++G+ + +R ++ + AHF+ +
Sbjct: 177 FLGLNKEGQAMKGNRVKKTKPAAHFLPK 204
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.133 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,156,549
Number of Sequences: 37866
Number of extensions: 347363
Number of successful extensions: 772
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 718
Number of HSP's gapped (non-prelim): 45
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.