Search of human proteins with 4503273

Search of human proteins with 4503273

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503273 angiotensin I converting enzyme 1 isoform 1
precursor [Homo sapiens]
         (1306 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503273 angiotensin I converting enzyme 1 isoform 1 precursor...  2721   0.0  
gi|23238214 angiotensin I converting enzyme 1 isoform 2 precurso...  1382   0.0  
gi|11225609 angiotensin I converting enzyme 2 precursor [Homo sa...   513   e-145
gi|122891870 melanoma inhibitory activity family, member 3 [Homo...    37   0.16 
gi|42794779 myosin 18A isoform b [Homo sapiens]                        32   4.0  
gi|28416946 myosin 18A isoform a [Homo sapiens]                        32   4.0  
gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precur...    31   8.9  
gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precur...    31   8.9  

>gi|4503273 angiotensin I converting enzyme 1 isoform 1 precursor
            [Homo sapiens]
          Length = 1306

 Score = 2721 bits (7054), Expect = 0.0
 Identities = 1306/1306 (100%), Positives = 1306/1306 (100%)

Query: 1    MGAASGRRGPGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQV 60
            MGAASGRRGPGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQV
Sbjct: 1    MGAASGRRGPGLLLPLPLLLLLPPQPALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQV 60

Query: 61   LFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRI 120
            LFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRI
Sbjct: 61   LFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRI 120

Query: 121  IGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSR 180
            IGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSR
Sbjct: 121  IGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSR 180

Query: 181  SYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDL 240
            SYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDL
Sbjct: 181  SYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDL 240

Query: 241  EHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPF 300
            EHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPF
Sbjct: 241  EHLYQQLEPLYLNLHAFVRRALHRRYGDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPF 300

Query: 301  PDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCH 360
            PDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCH
Sbjct: 301  PDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPADGREVVCH 360

Query: 361  ASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAI 420
            ASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAI
Sbjct: 361  ASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAI 420

Query: 421  GDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFS 480
            GDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFS
Sbjct: 421  GDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFS 480

Query: 481  GRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQF 540
            GRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQF
Sbjct: 481  GRTPPSRYNFDWWYLRTKYQGICPPVTRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQF 540

Query: 541  HEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLL 600
            HEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLL
Sbjct: 541  HEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLL 600

Query: 601  KYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTS 660
            KYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTS
Sbjct: 601  KYFQPVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLVTDEAEASKFVEEYDRTS 660

Query: 661  QVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRI 720
            QVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRI
Sbjct: 661  QVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRI 720

Query: 721  IKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKY 780
            IKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKY
Sbjct: 721  IKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKY 780

Query: 781  EDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLER 840
            EDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLER
Sbjct: 781  EDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLER 840

Query: 841  LFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPS 900
            LFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPS
Sbjct: 841  LFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPS 900

Query: 901  APSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHAS 960
            APSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHAS
Sbjct: 901  APSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHAS 960

Query: 961  AWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGD 1020
            AWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGD
Sbjct: 961  AWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGD 1020

Query: 1021 VLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGS 1080
            VLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGS
Sbjct: 1021 VLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGS 1080

Query: 1081 ITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHE 1140
            ITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHE
Sbjct: 1081 ITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHE 1140

Query: 1141 ALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSY 1200
            ALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSY
Sbjct: 1141 ALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSY 1200

Query: 1201 FKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQW 1260
            FKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQW
Sbjct: 1201 FKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQW 1260

Query: 1261 LLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSEVELRHS 1306
            LLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSEVELRHS
Sbjct: 1261 LLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSEVELRHS 1306


>gi|23238214 angiotensin I converting enzyme 1 isoform 2 precursor
            [Homo sapiens]
          Length = 732

 Score = 1382 bits (3576), Expect = 0.0
 Identities = 665/666 (99%), Positives = 666/666 (100%)

Query: 641  DLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKY 700
            +LVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKY
Sbjct: 67   NLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKY 126

Query: 701  GTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPN 760
            GTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPN
Sbjct: 127  GTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPN 186

Query: 761  GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD 820
            GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD
Sbjct: 187  GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVD 246

Query: 821  AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLL 880
            AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLL
Sbjct: 247  AGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLL 306

Query: 881  GNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEF 940
            GNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEF
Sbjct: 307  GNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEF 366

Query: 941  WNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYK 1000
            WNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYK
Sbjct: 367  WNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYK 426

Query: 1001 DLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKI 1060
            DLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKI
Sbjct: 427  DLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKI 486

Query: 1061 AFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIP 1120
            AFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIP
Sbjct: 487  AFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIP 546

Query: 1121 SSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWP 1180
            SSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWP
Sbjct: 547  SSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWP 606

Query: 1181 EAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDS 1240
            EAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDS
Sbjct: 607  EAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDS 666

Query: 1241 GRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSE 1300
            GRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSE
Sbjct: 667  GRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSE 726

Query: 1301 VELRHS 1306
            VELRHS
Sbjct: 727  VELRHS 732



 Score =  708 bits (1828), Expect = 0.0
 Identities = 337/637 (52%), Positives = 437/637 (68%), Gaps = 15/637 (2%)

Query: 27  ALALDPGLQPGNFSADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEA 86
           A A     Q  N   DEA A  F + Y+ +++ V  +   A+W ++TNIT E ++   + 
Sbjct: 56  ATAHQTSAQSPNLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQK 115

Query: 87  ALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSN 146
            +        +G +A++      QN T   ++RII  V+ L  A LP  + ++YN +L +
Sbjct: 116 NMQIANHTLKYGTQARKFDVNQLQNTT---IKRIIKKVQDLERAALPAQELEEYNKILLD 172

Query: 147 MSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYED 206
           M   YS A VC PN   +C  L+PDLTN++A+SR Y  LL+AWEGW + AG  +   Y  
Sbjct: 173 METTYSVATVCHPN--GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPK 230

Query: 207 FTALSNEAYKQDGFTDTGAYWRSWYNSPTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRY 266
           +  L N+A + +G+ D G  WRS Y +P+ E DLE L+Q+L+PLYLNLHA+VRRALHR Y
Sbjct: 231 YVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHY 290

Query: 267 GDRYINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVA 326
           G ++INL GPIPAHLLG+MWAQ+W NIYD+VVPFP  P++D T  ML+QGW    MF+ A
Sbjct: 291 GAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEA 350

Query: 327 EEFFTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLS 386
           ++FFTSL L P+PPEFW  SMLEKP DGREVVCHASAWDFYN KDFRIKQCT V ++ L 
Sbjct: 351 DDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLV 410

Query: 387 TVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTND 446
             HHEMGHIQY++QYKDLPV+LR GANPGFHEAIGDVLALSVSTP+HLH + LL      
Sbjct: 411 VAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGS 470

Query: 447 TESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPV 506
            E DIN+L+KMAL+KIAF+PF YLVDQWRW VF G      YN +WW LR KYQG+CPPV
Sbjct: 471 DEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPV 530

Query: 507 TRNETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAG 566
            R +  FD GAKFH+P+  PYIRYFVSF++QFQFHEALC+ AG+ GPLH+CDIY+S +AG
Sbjct: 531 PRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAG 590

Query: 567 AKLRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEY 626
            +L   ++ G SRPW E ++ + G   + A  +L YF+P+  WL+ +N+ +GE LGWP+Y
Sbjct: 591 QRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQY 650

Query: 627 QWHP-------PLPDNYPE---GIDLVTDEAEASKFV 653
            W P       PLPD+      G+DL   +A   +++
Sbjct: 651 NWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQWL 687


>gi|11225609 angiotensin I converting enzyme 2 precursor [Homo
            sapiens]
          Length = 805

 Score =  513 bits (1320), Expect = e-145
 Identities = 252/603 (41%), Positives = 373/603 (61%), Gaps = 18/603 (2%)

Query: 644  TDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQ 703
            T E +A  F+++++  ++ ++ + + A+WNYNTNIT E  + +     + +    +  T 
Sbjct: 20   TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTL 79

Query: 704  ARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNG-- 761
            A+ + + ++QN T+K  ++ +Q    + L   + +  N IL  M T YS   VC+P+   
Sbjct: 80   AQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQ 139

Query: 762  SCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDA 821
             CL LEP L  +MA S  Y + LWAWE WR + G+ +   Y +YV L N+ AR N Y D 
Sbjct: 140  ECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDY 199

Query: 822  GDSWRSMYETPSLE----------QDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINL 871
            GD WR  YE   ++          +D+E  F+E++PLY +LHAYVR  L   Y + +I+ 
Sbjct: 200  GDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISP 258

Query: 872  EGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSL 931
             G +PAHLLG+MW + W+N+Y L VPF   P++D T+AM+ Q W  +R+FKEA+ FF S+
Sbjct: 259  IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSV 318

Query: 932  GLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMG 991
            GL  +   FW  SML  P + ++ VCH +AWD   G DFRI  CT V ++D + AHHEMG
Sbjct: 319  GLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKG-DFRILMCTKVTMDDFLTAHHEMG 377

Query: 992  HIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSD-EHDIN 1050
            HIQY M Y   P  LR GAN GFHEA+G++++LS +TPKHL S+ LLS +   D E +IN
Sbjct: 378  HIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEIN 437

Query: 1051 FLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGD 1110
            FL+K AL  +  +PF+Y++++WRW VF G I K+ + ++WW ++ +  G+  PVP  +  
Sbjct: 438  FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497

Query: 1111 FDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATA 1170
             DP + FH+ +   +IRY+   + QFQF EALCQAA H GPLHKCDI  S EAGQ+L   
Sbjct: 498  CDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNM 557

Query: 1171 MKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNS 1230
            ++LG S PW  A++ + G  NM+   +L+YF+PL  WL+ +N+     +GW   +W+P +
Sbjct: 558  LRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNK--NSFVGW-STDWSPYA 614

Query: 1231 ARS 1233
             +S
Sbjct: 615  DQS 617



 Score =  498 bits (1282), Expect = e-140
 Identities = 254/602 (42%), Positives = 360/602 (59%), Gaps = 19/602 (3%)

Query: 40  SADEAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQ 99
           S  E  A+ F   +N  AE + +QS  ASW ++TNIT EN +    A      F +    
Sbjct: 19  STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQST 78

Query: 100 KAKELYEPIWQNFTDPQLRRIIGAVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLP 159
            A+       QN T   ++  + A++  GS+ L   K ++ N +L+ MS IYST KVC P
Sbjct: 79  LAQMYPLQEIQNLT---VKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNP 135

Query: 160 NKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKPLYEDFTALSNEAYKQDG 219
           +    C  L+P L  I+A+S  Y   L+AWE W +  G  L+PLYE++  L NE  + + 
Sbjct: 136 DNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANH 195

Query: 220 FTDTGAYWRSWYNSPTFE----------DDLEHLYQQLEPLYLNLHAFVRRALHRRYGDR 269
           + D G YWR  Y     +          +D+EH +++++PLY +LHA+VR  L   Y   
Sbjct: 196 YEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS- 254

Query: 270 YINLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEF 329
           YI+  G +PAHLLGDMW + W N+Y + VPF  KPN+DVT  M+ Q W+A  +F+ AE+F
Sbjct: 255 YISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKF 314

Query: 330 FTSLELSPMPPEFWEGSMLEKPADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVH 389
           F S+ L  M   FWE SML  P + ++ VCH +AWD   + DFRI  CT+VTMD   T H
Sbjct: 315 FVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDL-GKGDFRILMCTKVTMDDFLTAH 373

Query: 390 HEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDR-VTNDTE 448
           HEMGHIQY + Y   P  LR GAN GFHEA+G++++LS +TP+HL  IGLL      D E
Sbjct: 374 HEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNE 433

Query: 449 SDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTR 508
           ++IN+LLK AL  +  LPF Y++++WRW VF G  P  ++   WW ++ +  G+  PV  
Sbjct: 434 TEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPH 493

Query: 509 NETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAK 568
           +ET+ D  + FHV N   +IRY+   + QFQF EALC+ A +EGPLH+CDI  ST+AG K
Sbjct: 494 DETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQK 553

Query: 569 LRKVLQAGSSRPWQEVLKDMVGLDALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQW 628
           L  +L+ G S PW   L+++VG   ++ +PLL YF+P+  WL++QN+ +   +GW    W
Sbjct: 554 LFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGW-STDW 610

Query: 629 HP 630
            P
Sbjct: 611 SP 612


>gi|122891870 melanoma inhibitory activity family, member 3 [Homo
            sapiens]
          Length = 1907

 Score = 36.6 bits (83), Expect = 0.16
 Identities = 32/138 (23%), Positives = 62/138 (44%), Gaps = 3/138 (2%)

Query: 647  AEASKFVEEYDRTSQ--VVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQA 704
            AE S+ ++ ++++ +   V   + + N N  TN  T+ + +  +   +  N       + 
Sbjct: 1375 AELSEQIKSFEKSQKDLEVALTHKDDNINALTNCITQLNLLECESESEGQNKGGNDSDEL 1434

Query: 705  RKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCL 764
               +V   +N  +K  IK++ D+ R       +EE  K LL ++   SV+T C+      
Sbjct: 1435 ANGEVGGDRNEKMKNQIKQMMDVSRTQTAISVVEEDLK-LLQLKLRASVSTKCNLEDQVK 1493

Query: 765  QLEPDLTNVMATSRKYED 782
            +LE D  ++ A     ED
Sbjct: 1494 KLEDDRNSLQAAKAGLED 1511


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 50/187 (26%), Positives = 74/187 (39%), Gaps = 32/187 (17%)

Query: 699  KYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCH 758
            K  T  R     QL    I+   +++Q L R+ L   E +E N++ L+ +   S  +   
Sbjct: 1238 KLFTTVRPLIEVQLSEEQIRNKDEEIQQL-RSKLEKAE-KERNELRLNSDRLESRIS--- 1292

Query: 759  PNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQ------- 811
                  +L  +LT+   T      LL A    R +A + + +   +Y  L  Q       
Sbjct: 1293 ------ELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEME 1346

Query: 812  --------AARLNGYVD---AGDSWRSMYETPSLEQDL--ERLFQELQPLYLNLHAYVRR 858
                    AA +NG VD   AG  WR  YE    E D   +RL QE +   L +    +R
Sbjct: 1347 VMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFED-KLEVEQQNKR 1405

Query: 859  ALHRHYG 865
             L R  G
Sbjct: 1406 QLERRLG 1412


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 32.0 bits (71), Expect = 4.0
 Identities = 50/187 (26%), Positives = 74/187 (39%), Gaps = 32/187 (17%)

Query: 699  KYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCH 758
            K  T  R     QL    I+   +++Q L R+ L   E +E N++ L+ +   S  +   
Sbjct: 1238 KLFTTVRPLIEVQLSEEQIRNKDEEIQQL-RSKLEKAE-KERNELRLNSDRLESRIS--- 1292

Query: 759  PNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQ------- 811
                  +L  +LT+   T      LL A    R +A + + +   +Y  L  Q       
Sbjct: 1293 ------ELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEME 1346

Query: 812  --------AARLNGYVD---AGDSWRSMYETPSLEQDL--ERLFQELQPLYLNLHAYVRR 858
                    AA +NG VD   AG  WR  YE    E D   +RL QE +   L +    +R
Sbjct: 1347 VMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFED-KLEVEQQNKR 1405

Query: 859  ALHRHYG 865
             L R  G
Sbjct: 1406 QLERRLG 1412


>gi|14196451 protocadherin gamma subfamily A, 11 isoform 2 precursor
           [Homo sapiens]
          Length = 837

 Score = 30.8 bits (68), Expect = 8.9
 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 5/80 (6%)

Query: 402 KDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEK 461
           + L V+++    P     +   +A++ S PE L  +G L+ + N   SD++  L +A+  
Sbjct: 641 QSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETSDLSLYLVVAVAA 700

Query: 462 IA--FLPFGYL---VDQWRW 476
           ++  FL F  +   +  WRW
Sbjct: 701 VSCIFLVFVIVLLALRLWRW 720


>gi|11128039 protocadherin gamma subfamily A, 11 isoform 1 precursor
           [Homo sapiens]
          Length = 935

 Score = 30.8 bits (68), Expect = 8.9
 Identities = 21/80 (26%), Positives = 40/80 (50%), Gaps = 5/80 (6%)

Query: 402 KDLPVSLRRGANPGFHEAIGDVLALSVSTPEHLHKIGLLDRVTNDTESDINYLLKMALEK 461
           + L V+++    P     +   +A++ S PE L  +G L+ + N   SD++  L +A+  
Sbjct: 641 QSLVVAVQDHGQPPLSATVTLTVAVADSIPEVLADLGSLESLANSETSDLSLYLVVAVAA 700

Query: 462 IA--FLPFGYL---VDQWRW 476
           ++  FL F  +   +  WRW
Sbjct: 701 VSCIFLVFVIVLLALRLWRW 720


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,457,268
Number of Sequences: 37866
Number of extensions: 2530191
Number of successful extensions: 6066
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 6040
Number of HSP's gapped (non-prelim): 14
length of query: 1306
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1192
effective length of database: 13,930,794
effective search space: 16605506448
effective search space used: 16605506448
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.