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Search of human proteins with 4503011
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
(458 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 955 0.0
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 417 e-116
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 387 e-107
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 387 e-107
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 387 e-107
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 382 e-106
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 380 e-105
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 366 e-101
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 350 2e-96
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 307 1e-83
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 307 1e-83
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 307 1e-83
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 57 3e-08
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 48 2e-05
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 46 8e-05
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 44 3e-04
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 37 0.029
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 37 0.037
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 32 1.6
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 31 2.7
gi|22538422 activating transcription factor 2 [Homo sapiens] 30 3.5
gi|4501869 acyl-Coenzyme A oxidase 2 [Homo sapiens] 30 4.6
gi|32455260 peroxiredoxin 5 isoform b precursor [Homo sapiens] 29 7.8
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 29 7.8
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 955 bits (2468), Expect = 0.0
Identities = 458/458 (100%), Positives = 458/458 (100%)
Query: 1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL 60
MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL
Sbjct: 1 MSDLLSVFLHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHL 60
Query: 61 YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD 120
YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD
Sbjct: 61 YVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQD 120
Query: 121 TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN 180
TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN
Sbjct: 121 TRIHILPSMNPDGYEVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN 180
Query: 181 HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT 240
HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT
Sbjct: 181 HHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRT 240
Query: 241 ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT 300
ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT
Sbjct: 241 ASTPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHT 300
Query: 301 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS 360
NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS
Sbjct: 301 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS 360
Query: 361 VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP 420
VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP
Sbjct: 361 VSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIP 420
Query: 421 QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA 458
QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA
Sbjct: 421 QVSPVRRAPSRRHGVRAKVQPQARKKEMEMRQLQRGPA 458
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 417 bits (1072), Expect = e-116
Identities = 210/408 (51%), Positives = 280/408 (68%), Gaps = 18/408 (4%)
Query: 21 VTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 80
++F +HRY +L L V +C I+R+Y++GRS EGR L V+E SD+PG+HEP EPE K
Sbjct: 49 ISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFK 108
Query: 81 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 140
Y+GNMHGNEA+GREL++ L+++LC E++ N+ IV LI TRIHI+PS+NPDG+E AA+Q
Sbjct: 109 YIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQ 168
Query: 141 GPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHL-----PLPDNWKSQVEP 195
+ VGR+NA G+DLNRNFPDL+ +Y NEK GGPN+HL + D +++ P
Sbjct: 169 PGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQ-NTKLAP 227
Query: 196 ETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLA 255
ET+AVI W+ FVLSANLHGG +VANYPYD++ R + +PDD +FQ LA
Sbjct: 228 ETKAVIHWIMDIPFVLSANLHGGDLVANYPYDET-----RSGSAHEYSSSPDDAIFQSLA 282
Query: 256 KVYSYAHGWM-------FQGWNCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLE 308
+ YS + M + + F DG TNG +WYS+ GMQDFNYL +NCFEIT+E
Sbjct: 283 RAYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVE 342
Query: 309 LSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDV 368
LSC+KFPPEE L+ W N+ +LI +LEQ+H+G+KG V D N +ANA ISV GI+HDV
Sbjct: 343 LSCEKFPPEETLKTYWEDNKNSLISYLEQIHRGVKGFVRDLQGNPIANATISVEGIDHDV 402
Query: 369 TSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLK 416
TS GDY+RLL+PG Y ++A+APGY T V V + V+F L+
Sbjct: 403 TSAKDGDYWRLLIPGNYKLTASAPGYLAITKKVAVPYSPAAGVDFELE 450
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 387 bits (993), Expect = e-107
Identities = 193/380 (50%), Positives = 253/380 (66%), Gaps = 10/380 (2%)
Query: 21 VTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 80
+ F HH Y +VR L + + C + R YSIGRS +GR L V+EFS PG HE +EPEVK
Sbjct: 46 IRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVK 105
Query: 81 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 140
+GN+HGNE GRE+++ L+++LC E+ N RI +L+ TRIH+LPSMNPDGYEVAAA+
Sbjct: 106 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAE 165
Query: 141 GPNKPGYLVGRNNANGVDLNRNFPDLNT-YIYYNEKYGGPNHHLPLPDN-WKSQVEPETR 198
G G+ GR NA +DLNRNFPDL + Y E G + H+P+P + W +V PET+
Sbjct: 166 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETK 225
Query: 199 AVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVY 258
A+++WM + FVLSA+LHGG +V +YP+D S + +PTPD+K+F+ L++ Y
Sbjct: 226 AIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQ----EEKMFSPTPDEKMFKLLSRAY 281
Query: 259 SYAHGWMFQGW--NCGDYF--PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 314
+ H M CG F I NGA WYS + GM DFNYLHTNCFEIT+EL C KF
Sbjct: 282 ADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKF 341
Query: 315 PPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHG 374
PPEE L W N+E+L+ F+E VH+GIKG+V D+ + NA ISV GI HD+T+ G
Sbjct: 342 PPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDG 401
Query: 375 DYFRLLLPGIYTVSATAPGY 394
DY+RLL PGI+ V A APGY
Sbjct: 402 DYWRLLPPGIHIVIAQAPGY 421
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 387 bits (993), Expect = e-107
Identities = 193/380 (50%), Positives = 253/380 (66%), Gaps = 10/380 (2%)
Query: 21 VTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 80
+ F HH Y +VR L + + C + R YSIGRS +GR L V+EFS PG HE +EPEVK
Sbjct: 172 IRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVK 231
Query: 81 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 140
+GN+HGNE GRE+++ L+++LC E+ N RI +L+ TRIH+LPSMNPDGYEVAAA+
Sbjct: 232 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAE 291
Query: 141 GPNKPGYLVGRNNANGVDLNRNFPDLNT-YIYYNEKYGGPNHHLPLPDN-WKSQVEPETR 198
G G+ GR NA +DLNRNFPDL + Y E G + H+P+P + W +V PET+
Sbjct: 292 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETK 351
Query: 199 AVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVY 258
A+++WM + FVLSA+LHGG +V +YP+D S + +PTPD+K+F+ L++ Y
Sbjct: 352 AIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQ----EEKMFSPTPDEKMFKLLSRAY 407
Query: 259 SYAHGWMFQGW--NCGDYF--PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 314
+ H M CG F I NGA WYS + GM DFNYLHTNCFEIT+EL C KF
Sbjct: 408 ADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKF 467
Query: 315 PPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHG 374
PPEE L W N+E+L+ F+E VH+GIKG+V D+ + NA ISV GI HD+T+ G
Sbjct: 468 PPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDG 527
Query: 375 DYFRLLLPGIYTVSATAPGY 394
DY+RLL PGI+ V A APGY
Sbjct: 528 DYWRLLPPGIHIVIAQAPGY 547
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 387 bits (993), Expect = e-107
Identities = 193/380 (50%), Positives = 253/380 (66%), Gaps = 10/380 (2%)
Query: 21 VTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVK 80
+ F HH Y +VR L + + C + R YSIGRS +GR L V+EFS PG HE +EPEVK
Sbjct: 183 IRFSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVK 242
Query: 81 YVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQ 140
+GN+HGNE GRE+++ L+++LC E+ N RI +L+ TRIH+LPSMNPDGYEVAAA+
Sbjct: 243 LIGNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAE 302
Query: 141 GPNKPGYLVGRNNANGVDLNRNFPDLNT-YIYYNEKYGGPNHHLPLPDN-WKSQVEPETR 198
G G+ GR NA +DLNRNFPDL + Y E G + H+P+P + W +V PET+
Sbjct: 303 GAGYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETRGARSDHIPIPQHYWWGKVAPETK 362
Query: 199 AVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVY 258
A+++WM + FVLSA+LHGG +V +YP+D S + +PTPD+K+F+ L++ Y
Sbjct: 363 AIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQ----EEKMFSPTPDEKMFKLLSRAY 418
Query: 259 SYAHGWMFQGW--NCGDYF--PDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 314
+ H M CG F I NGA WYS + GM DFNYLHTNCFEIT+EL C KF
Sbjct: 419 ADVHPMMMDRSENRCGGNFLKRGSIINGADWYSFTGGMSDFNYLHTNCFEITVELGCVKF 478
Query: 315 PPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHDVTSGDHG 374
PPEE L W N+E+L+ F+E VH+GIKG+V D+ + NA ISV GI HD+T+ G
Sbjct: 479 PPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVKNARISVKGIRHDITTAPDG 538
Query: 375 DYFRLLLPGIYTVSATAPGY 394
DY+RLL PGI+ V A APGY
Sbjct: 539 DYWRLLPPGIHIVIAQAPGY 558
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 382 bits (982), Expect = e-106
Identities = 200/410 (48%), Positives = 265/410 (64%), Gaps = 35/410 (8%)
Query: 15 FKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEP 74
++ + P F HH + D+ L + NE P ITR+YS+G+SVE R LYV+E SD+PG+HEP
Sbjct: 493 YQPIQPKDFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEP 552
Query: 75 LEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGY 134
EPE KY+GNMHGNE +GREL+L L E+LC+ F + + L+ +TRIH++PSMNPDGY
Sbjct: 553 GEPEFKYIGNMHGNEVVGRELLLNLIEYLCKNF-GTDPEVTDLVHNTRIHLMPSMNPDGY 611
Query: 135 EVAAAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVE 194
E + +G + ++GRNN+N DLNRNFPD I +
Sbjct: 612 E-KSQEGDSIS--VIGRNNSNNFDLNRNFPDQFVQI-------------------TDPTQ 649
Query: 195 PETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKL 254
PET AV+ WM S+ FVLSANLHGG++V NYP+D + + +PDD +FQ++
Sbjct: 650 PETIAVMSWMKSYPFVLSANLHGGSLVVNYPFDDDEQ------GLATYSKSPDDAVFQQI 703
Query: 255 AKVYSYAHGWMFQGWNC-----GDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLEL 309
A YS + MFQG C +YFP GITNGASWY++ GMQD+NYL TNCFE+T+EL
Sbjct: 704 ALSYSKENSQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIEL 763
Query: 310 SCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLD-ENYNNLANAVISVSGINHDV 368
C K+P E+EL W NR +LIQF++QVHQG++G VLD + + NA ISV+ INH V
Sbjct: 764 GCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATDGRGILNATISVAEINHPV 823
Query: 369 TSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRS 418
T+ GDY+RLL+PG Y ++A+A GY+P T VTV VNF L RS
Sbjct: 824 TTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSEGAIQVNFTLVRS 873
Score = 307 bits (787), Expect = 1e-83
Identities = 179/412 (43%), Positives = 244/412 (59%), Gaps = 50/412 (12%)
Query: 43 PGITRVYSIGRSVEGRHLYVLEFS-------------------DHPGIHEPLEPEVKYVG 83
PG+ R++SIGRSVEGR L+VL + D G P P+VK VG
Sbjct: 77 PGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVG 136
Query: 84 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVA----AA 139
NMHG+E + R++++ L+ L +R + R+V+L+ T +++LPS+NPDG+E A
Sbjct: 137 NMHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCG 196
Query: 140 QGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRA 199
G P GR+N+ G DLNR+FPD G P P D PE RA
Sbjct: 197 FGDGGPSGASGRDNSRGRDLNRSFPD-------QFSTGEP----PALDE-----VPEVRA 240
Query: 200 VIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKVYS 259
+I W+ FVLS NLHGG+VVA+YP+D S EH+ G+ + T DD++F+ LAK Y+
Sbjct: 241 LIEWIRRNKFVLSGNLHGGSVVASYPFDDSPEHKATGIY----SKTSDDEVFKYLAKAYA 296
Query: 260 YAHGWMFQGW-NC----GDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSCDKF 314
H M G +C + F DGITNGA WY + GMQD+NY+ NCFEITLELSC K+
Sbjct: 297 SNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGGMQDYNYVWANCFEITLELSCCKY 356
Query: 315 PPEEELQREWLGNREALIQFLEQVHQGIKGMVLDE-NYNNLANAVISVSGINHDVTSGDH 373
PP +L++EW NRE+LI +E+VH G+KG V D + L NA ISV+GINH++T+G
Sbjct: 357 PPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSITGSGLENATISVAGINHNITTGRF 416
Query: 374 GDYFRLLLPGIYTVSATAPGYDPETVT-VTVGPAEPTLVNFHLKRSIPQVSP 424
GD++RLL+PG Y ++ GY P TVT V V T V+F L+ ++ V P
Sbjct: 417 GDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPATEVDFSLRPTVTSVIP 468
Score = 194 bits (494), Expect = 1e-49
Identities = 124/393 (31%), Positives = 199/393 (50%), Gaps = 50/393 (12%)
Query: 18 VAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEP 77
+A +R+H Y DL L + P IT + ++G+S E RH++ LE S+ P + EP EP
Sbjct: 926 LALALYRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEP 985
Query: 78 EVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVA 137
++++V +HGN +G EL+L L+EFLC ++ +N + QL+ TRI I+PS+NPDG E A
Sbjct: 986 KIRFVAGIHGNAPVGTELLLALAEFLCLNYK-KNPAVTQLVDRTRIVIVPSLNPDGRERA 1044
Query: 138 AAQGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPET 197
+ +G+ NA G DL+ +F + + +PET
Sbjct: 1045 QEKDCTSK---IGQTNARGKDLDTDFTN-------------------------NASQPET 1076
Query: 198 RAVI-RWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAK 256
+A+I + +F LS L GG+++ YPYDK + + + + LA
Sbjct: 1077 KAIIENLIQKQDFSLSVALDGGSMLVTYPYDKPVQ------------TVENKETLKHLAS 1124
Query: 257 VYSYAHGWMFQGW-----NCGDYFPDGITNGASWYSLSKGMQDFNYLHTNCFEITLELSC 311
+Y+ H M G + P G+ GA W+S M+D++ + +C EIT+ SC
Sbjct: 1125 LYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKDYSVTYGHCPEITVYTSC 1184
Query: 312 DKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVS-GINHDVTS 370
FP L W N+ +L+ L +VH+G+ G V D+ ++ AVI ++ GI V +
Sbjct: 1185 CYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPISKAVIVLNEGIK--VQT 1242
Query: 371 GDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403
+ G + LL PG++ + A A GY + V V
Sbjct: 1243 KEGGYFHVLLAPGVHNIIAIADGYQQQHSQVFV 1275
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 380 bits (976), Expect = e-105
Identities = 214/447 (47%), Positives = 283/447 (63%), Gaps = 25/447 (5%)
Query: 20 PVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEV 79
P+ F+HH Y + + + +VQ +CP ITR+YSIG+S +G LYV+E SD PG HE EPEV
Sbjct: 294 PLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEV 353
Query: 80 KYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAA 139
+YV MHGNEALGREL+L L +FLC EF N R+ +L+ + RIH+LPSMNPDGYE+A
Sbjct: 354 RYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYH 413
Query: 140 QGPNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGG-----PNHHLPLPDNW---KS 191
+G G+ GR N +DLN NF DLNT ++ + G PNHHLPLP + +
Sbjct: 414 RGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPNA 473
Query: 192 QVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLF 251
V PETRAVI+WM FVLSANLHGG +V +YP+D + R R TPTPDD +F
Sbjct: 474 TVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMT---RTPWAAREL-TPTPDDAVF 529
Query: 252 QKLAKVYSYAHGWM----FQGWNCGDYFPDG-ITNGASWYSLSKGMQDFNYLHTNCFEIT 306
+ L+ VY+ ++ M + + D+ G I NGA W+++ M DF+YLHTNCFE+T
Sbjct: 530 RWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVT 589
Query: 307 LELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYN-NLANAVISVSGIN 365
+ELSCDKFP E EL +EW N++AL+ +LEQV GI G+V D++ +A+AVI+V GIN
Sbjct: 590 VELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGVVRDKDTELGIADAVIAVDGIN 649
Query: 366 HDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVGPAE-PTLVNFHLKRSIPQVSP 424
HDVT+ GDY+RLL PG Y V+A+A GY T V E P NF L + +P
Sbjct: 650 HDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVTFEEGPFPCNFVLTK-----TP 704
Query: 425 VRRAPSRRHGVRAKVQPQARKKEMEMR 451
+R AKV P R++ +R
Sbjct: 705 KQRL-RELLAAGAKVPPDLRRRLERLR 730
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 366 bits (940), Expect = e-101
Identities = 202/450 (44%), Positives = 275/450 (61%), Gaps = 25/450 (5%)
Query: 23 FRHHRYDDLVRTLYKVQNE-CPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKY 81
F+HH Y ++ R L KV NE CP ITR+Y+IG+S +G LY +E SDHPG HE EPE Y
Sbjct: 316 FKHHNYKEM-RQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHY 374
Query: 82 VGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQG 141
+ HGNE LGREL+L L +F+C+E+ RN RIV L+++TRIH+LPS+NPDGYE A G
Sbjct: 375 IAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGG 434
Query: 142 PNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGG-----PNHHLPLPDNWKSQ---V 193
G+ +GR +G+D+N NFPDLNT ++ E PNH++ +P+ + S+ V
Sbjct: 435 SELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENATV 494
Query: 194 EPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS-TPTPDDKLFQ 252
ETRAVI WM FVL NL GG +V YPYD VR +T TPTPDD +F+
Sbjct: 495 AAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYD-----LVRSPWKTQEHTPTPDDHVFR 549
Query: 253 KLAKVYSYAHGWMFQGWNCGDYFPD-----GITNGASWYSLSKGMQDFNYLHTNCFEITL 307
LA Y+ H M + D G NGASW++++ + DF+YLHTNCFE+++
Sbjct: 550 WLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLNDFSYLHTNCFELSI 609
Query: 308 ELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVISVSGINHD 367
+ CDK+P E +L EW NRE+LI F+EQVH+GIKG+V D + + NA+ISV GINHD
Sbjct: 610 YVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKGIPNAIISVEGINHD 669
Query: 368 VTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVG-PAEPTLVNFHLKRSIPQVSPVR 426
+ + + GDY+RLL PG Y V+A A G+ T VG T +F L ++ ++ +R
Sbjct: 670 IRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCDFTLSKT--NMARIR 727
Query: 427 RAPSRRHGVRAKVQPQARKKEMEMRQLQRG 456
+ G + P R K ++ QRG
Sbjct: 728 EI-MEKFGKQPVSLPARRLKLRGQKRRQRG 756
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 350 bits (897), Expect = 2e-96
Identities = 200/477 (41%), Positives = 272/477 (57%), Gaps = 46/477 (9%)
Query: 23 FRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYV 82
FRHH Y D+ + + V ECP ITR YS+G+S G +Y +E SD+PG HE EPE +Y
Sbjct: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621
Query: 83 GNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP 142
+HGNE LGREL+L L ++LC E+R+ N R+ L+QDTRIH++PS+NPDGYEVAA G
Sbjct: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681
Query: 143 NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEK-----YGGPNHHLPLPDNWKS---QVE 194
+ +G G D+ +FPDLN+ ++ E+ Y PN++LP+P+ + S V
Sbjct: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741
Query: 195 PETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTA------------- 241
E RA+I WM FVL ANL+GG + +YPYD + + A
Sbjct: 742 TEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEVS 801
Query: 242 -STPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPD-----GITNGASWYSLSKGMQDF 295
+ TPD +F+ LA ++ AH + + + G D GI NGA W + + DF
Sbjct: 802 EAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDF 861
Query: 296 NYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLA 355
+YLHTNC E++ L CDKFP E EL REW N+EAL+ F+EQVH+GIKG+V DE +A
Sbjct: 862 SYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIA 921
Query: 356 NAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVG-PAEPTLVNFH 414
NA ISVSGINH V + GDY+R+L PG Y V+A A GY P T V T NF
Sbjct: 922 NATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCNFI 981
Query: 415 LKRS----------------IPQVSPVR-RAPSRRHGVRAKVQPQAR-KKEMEMRQL 453
L RS IP + P R P +R + ++Q + R + +M +R+L
Sbjct: 982 LARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQRRLQHRLRLRAQMRLRRL 1038
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 307 bits (787), Expect = 1e-83
Identities = 174/405 (42%), Positives = 236/405 (58%), Gaps = 42/405 (10%)
Query: 9 LHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDH 68
L L LL LVA + F +HR + + L V +T ++SIG+SV+GR+L+VL
Sbjct: 6 LWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRF 65
Query: 69 PGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPS 128
P H PE KYV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PS
Sbjct: 66 PKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINSTRIHIMPS 124
Query: 129 MNPDGYEVAAAQGPNKPG--YLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLP 186
MNPDG+E KP Y +GR N N DLNRNFPD Y +
Sbjct: 125 MNPDGFEAV-----KKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSR------------ 167
Query: 187 DNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS---- 242
+PET AV++W+ + FVLSANLHGGA+VA+YP+D GV+ T +
Sbjct: 168 -------QPETVAVMKWLKTETFVLSANLHGGALVASYPFDN-------GVQATGALYSR 213
Query: 243 TPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHT 300
+ TPDD +FQ LA Y+ + M +G C + FP+G+TNG SWY L GMQD+NY+
Sbjct: 214 SLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWA 273
Query: 301 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS 360
CFEITLELSC K+P EE+L W N+ +LI++++QVH G+KG V D+N N L N ++
Sbjct: 274 QCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVE 333
Query: 361 VSGINH--DVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403
V H + +G+Y+ LLLPG Y ++ T PG+DP V +
Sbjct: 334 VQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 307 bits (787), Expect = 1e-83
Identities = 174/405 (42%), Positives = 236/405 (58%), Gaps = 42/405 (10%)
Query: 9 LHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDH 68
L L LL LVA + F +HR + + L V +T ++SIG+SV+GR+L+VL
Sbjct: 6 LWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRF 65
Query: 69 PGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPS 128
P H PE KYV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PS
Sbjct: 66 PKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINSTRIHIMPS 124
Query: 129 MNPDGYEVAAAQGPNKPG--YLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLP 186
MNPDG+E KP Y +GR N N DLNRNFPD Y +
Sbjct: 125 MNPDGFEAV-----KKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSR------------ 167
Query: 187 DNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS---- 242
+PET AV++W+ + FVLSANLHGGA+VA+YP+D GV+ T +
Sbjct: 168 -------QPETVAVMKWLKTETFVLSANLHGGALVASYPFDN-------GVQATGALYSR 213
Query: 243 TPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHT 300
+ TPDD +FQ LA Y+ + M +G C + FP+G+TNG SWY L GMQD+NY+
Sbjct: 214 SLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWA 273
Query: 301 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS 360
CFEITLELSC K+P EE+L W N+ +LI++++QVH G+KG V D+N N L N ++
Sbjct: 274 QCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVE 333
Query: 361 VSGINH--DVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403
V H + +G+Y+ LLLPG Y ++ T PG+DP V +
Sbjct: 334 VQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 307 bits (787), Expect = 1e-83
Identities = 174/405 (42%), Positives = 236/405 (58%), Gaps = 42/405 (10%)
Query: 9 LHLLLLFKLVAPVTFRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDH 68
L L LL LVA + F +HR + + L V +T ++SIG+SV+GR+L+VL
Sbjct: 6 LWLGLLLPLVAALDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRF 65
Query: 69 PGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPS 128
P H PE KYV NMHG+E +GREL+L L ++L ++ I LI TRIHI+PS
Sbjct: 66 PKEHRIGIPEFKYVANMHGDETVGRELLLHLIDYLVTS-DGKDPEITNLINSTRIHIMPS 124
Query: 129 MNPDGYEVAAAQGPNKPG--YLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLP 186
MNPDG+E KP Y +GR N N DLNRNFPD Y +
Sbjct: 125 MNPDGFEAV-----KKPDCYYSIGRENYNQYDLNRNFPDAFEYNNVSR------------ 167
Query: 187 DNWKSQVEPETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTAS---- 242
+PET AV++W+ + FVLSANLHGGA+VA+YP+D GV+ T +
Sbjct: 168 -------QPETVAVMKWLKTETFVLSANLHGGALVASYPFDN-------GVQATGALYSR 213
Query: 243 TPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDY--FPDGITNGASWYSLSKGMQDFNYLHT 300
+ TPDD +FQ LA Y+ + M +G C + FP+G+TNG SWY L GMQD+NY+
Sbjct: 214 SLTPDDDVFQYLAHTYASRNPNMKKGDECKNKMNFPNGVTNGYSWYPLQGGMQDYNYIWA 273
Query: 301 NCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLANAVIS 360
CFEITLELSC K+P EE+L W N+ +LI++++QVH G+KG V D+N N L N ++
Sbjct: 274 QCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGNPLPNVIVE 333
Query: 361 VSGINH--DVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTV 403
V H + +G+Y+ LLLPG Y ++ T PG+DP V +
Sbjct: 334 VQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPHITKVII 378
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 57.4 bits (137), Expect = 3e-08
Identities = 63/269 (23%), Positives = 106/269 (39%), Gaps = 47/269 (17%)
Query: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
+H + + + + + P + R IG S E R +YVL+FS G+ P V
Sbjct: 123 YHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVR---RPAVWLNAG 179
Query: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQG--- 141
+H E + + + + + +++ R+ I +++ I +LP NPDGY Q
Sbjct: 180 IHSREWISQATAIWTARKIVSDYQ-RDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLW 238
Query: 142 ----PNKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQV---- 193
PG ++ G D NRN +N + G DN S+V
Sbjct: 239 RKTRSRNPG-----SSCIGADPNRN---------WNASFAGKG----ASDNPCSEVYHGP 280
Query: 194 ----EPETRAVIRWMHSF-NFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDD 248
E E ++V+ ++ NF +LH + + YPY S + A D
Sbjct: 281 HANSEVEVKSVVDFIQKHGNFKGFIDLHSYSQLLMYPYGYSV--------KKAPDAEELD 332
Query: 249 KLFQKLAKVYSYAHGWMFQ-GWNCGDYFP 276
K+ + AK + G +Q G C +P
Sbjct: 333 KVARLAAKALASVSGTEYQVGPTCTTVYP 361
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/209 (22%), Positives = 91/209 (43%), Gaps = 22/209 (10%)
Query: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
+H +++ + + + E PG+ +IG S E R + VL+FS +P +
Sbjct: 123 YHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFSTGGD-----KPAIWLDAG 177
Query: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP-- 142
+H E + + L + + ++ ++ I ++ I +LP NPDGY + +
Sbjct: 178 IHAREWVTQATALWTANKIVSDY-GKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMW 236
Query: 143 NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPN-HHLPLPDNW---KSQVEPETR 198
K V + GVD NRN ++ +GGP P D++ + E E +
Sbjct: 237 RKTRSKVSGSLCVGVDPNRN---------WDAGFGGPGASSNPCSDSYHGPSANSEVEVK 287
Query: 199 AVIRWMHSFNFVLS-ANLHGGAVVANYPY 226
+++ ++ S V + LH + + +PY
Sbjct: 288 SIVDFIKSHGKVKAFITLHSYSQLLMFPY 316
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 45.8 bits (107), Expect = 8e-05
Identities = 49/215 (22%), Positives = 90/215 (41%), Gaps = 24/215 (11%)
Query: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
+H +++ ++ + G+ ++SIGRS EGR L++L+ G L+ V
Sbjct: 139 YHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCG 194
Query: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP-- 142
+H E +G + +++ + + +++ +I+P N DGY +
Sbjct: 195 IHAREWIGPAFCQWFVKEALLTYKS-DPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFW 253
Query: 143 NKPGYLVGRNNANGVDLNRNFP----DLNTYIY-YNEKYGGPNHHLPLPDNWKSQVEPET 197
K R GVD NRN+ D ++ ++ Y G P P++ EPE
Sbjct: 254 RKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCG-----PFPES-----EPEV 303
Query: 198 RAVIRWMHSFNFVLSANL--HGGAVVANYPYDKSF 230
+AV ++ + A L H A + YPY +
Sbjct: 304 KAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKY 338
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 43.9 bits (102), Expect = 3e-04
Identities = 46/191 (24%), Positives = 82/191 (42%), Gaps = 24/191 (12%)
Query: 24 RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 83
+++ ++ +V K+ ++ P + IG +VE LYVL+ + + + +
Sbjct: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRKAIFTDC---- 173
Query: 84 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPN 143
+H E + Q + + RN+ + +L+ +ILP N DGY + + N
Sbjct: 174 GIHAREWVS-PAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTK--N 230
Query: 144 KPGYLVGRNNAN----GVDLNRNFPDLNTYIYYNEKYGG-PNHHLPLPDNWKS---QVEP 195
+ N N G DLNRNF N + PN + P DN++ + E
Sbjct: 231 RMWRKNRSKNQNSKCIGTDLNRNF---------NASWNSIPNTNDPCADNYRGSAPESEK 281
Query: 196 ETRAVIRWMHS 206
ET+AV ++ S
Sbjct: 282 ETKAVTNFIRS 292
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 37.4 bits (85), Expect = 0.029
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 7/122 (5%)
Query: 44 GITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFL 103
G+ ++SIGRS EGR L++L+ G L+ V +H E +G +
Sbjct: 10 GLIHMFSIGRSYEGRSLFILKL----GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEA 65
Query: 104 CEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP--NKPGYLVGRNNANGVDLNR 161
+++ + + +++ +I+P N DGY + K R GVD NR
Sbjct: 66 LLTYKS-DPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANR 124
Query: 162 NF 163
N+
Sbjct: 125 NW 126
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 37.0 bits (84), Expect = 0.037
Identities = 50/246 (20%), Positives = 94/246 (38%), Gaps = 17/246 (6%)
Query: 24 RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 83
++H +++ + + P + IG S E LYVL+ S G + + +
Sbjct: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178
Query: 84 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP- 142
+H E + L + + + Q L++ +++P +N DGY+ + +
Sbjct: 179 GIHAREWISPAFCLWFIGHITQFYGIIGQ-YTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 237
Query: 143 -NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAVI 201
K N+ G DLNRNF ++ E+ + + EPE +AV
Sbjct: 238 WRKNRSFYANNHCIGTDLNRNFASK----HWCEEGASSSSCSETYCGLYPESEPEVKAVA 293
Query: 202 ----RWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKV 257
R ++ +S + + +V Y Y +S + AS + +K +K
Sbjct: 294 SFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV---RAIEKTSKN 350
Query: 258 YSYAHG 263
Y HG
Sbjct: 351 TRYTHG 356
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 31.6 bits (70), Expect = 1.6
Identities = 51/251 (20%), Positives = 95/251 (37%), Gaps = 28/251 (11%)
Query: 24 RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 83
++++++ + +V E P + IG + EGR +Y+L+ G +P +
Sbjct: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV----GKAGQNKPAIFMDC 173
Query: 84 NMHGNEALGRELMLQLSEFLCEEFR--NRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQG 141
H E + F+ E R R ++ +L+ ++LP +N DGY +
Sbjct: 174 GFHAREWISPAF---CQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKS 230
Query: 142 P--NKPGYLVGRNNANGVDLNRNFPDLNTYI-----YYNEKYGGPNHHLPLPDNWKSQVE 194
K ++ G D NRNF I +E Y GP ++ E
Sbjct: 231 RFWRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGP----------AAESE 280
Query: 195 PETRAVIRWMHSFNFVLSA--NLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQ 252
ET+A+ ++ + + A +H + + YPY +++ A +L
Sbjct: 281 KETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELAS 340
Query: 253 KLAKVYSYAHG 263
Y+Y G
Sbjct: 341 LHGTKYTYGPG 351
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 30.8 bits (68), Expect = 2.7
Identities = 31/143 (21%), Positives = 60/143 (41%), Gaps = 11/143 (7%)
Query: 25 HHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVGN 84
+H +++ L + E P + IG + EGR +YVL+FS P +
Sbjct: 122 YHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFSTGGS----KRPAIWIDTG 177
Query: 85 MHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGPNK 144
+H E + + + ++ + +++ ++ ++ I + NPDG+ A N+
Sbjct: 178 IHSREWVTQASGVWFAKKITQDY-GQDAAFTAILDTLDIFLEIVTNPDGF--AFTHSTNR 234
Query: 145 PGYLVGRNNAN----GVDLNRNF 163
+ A GVD NRN+
Sbjct: 235 MWRKTRSHTAGSLCIGVDPNRNW 257
>gi|22538422 activating transcription factor 2 [Homo sapiens]
Length = 505
Score = 30.4 bits (67), Expect = 3.5
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 381 LPGIYTVSATAPGYDPETVTVTVGPAEPTLVNFHLKRSIPQVSPVRRAPSRRHGVRAKVQ 440
+PG + + P + +T+ V + PA T N H+ ++P V PV PS G+
Sbjct: 211 VPGPFPLLLHLP--NGQTMPVAI-PASITSSNVHVPAAVPLVRPVTMVPS-VPGIPGPSS 266
Query: 441 PQARKKEMEMR 451
PQ + E +MR
Sbjct: 267 PQPVQSEAKMR 277
>gi|4501869 acyl-Coenzyme A oxidase 2 [Homo sapiens]
Length = 681
Score = 30.0 bits (66), Expect = 4.6
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 2/44 (4%)
Query: 177 GGPNHHLPLPDNWKSQVEPETRAVIRWMHSFNFVLSAN-LHGGA 219
G P H + L D W Q+ P+ + R+M SF+ N L GGA
Sbjct: 2 GSPVHRVSLGDTWSRQMHPDIESE-RYMQSFDVERLTNILDGGA 44
>gi|32455260 peroxiredoxin 5 isoform b precursor [Homo sapiens]
Length = 170
Score = 29.3 bits (64), Expect = 7.8
Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 69 PGIHEPLEPEVKYVGNMHGNEALGRELMLQLSEFLCEEFRNRN-QRIVQLIQDTRIHILP 127
PG P +V+ + + G A G+E L L + L F NR +R ++QD + L
Sbjct: 93 PGAFTPGCSKVRLLADPTG--AFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKAL- 149
Query: 128 SMNPDGYEVAAAQGPN 143
++ PDG + + PN
Sbjct: 150 NVEPDGTGLTCSLAPN 165
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 29.3 bits (64), Expect = 7.8
Identities = 16/42 (38%), Positives = 23/42 (54%), Gaps = 6/42 (14%)
Query: 358 VISVSGIN------HDVTSGDHGDYFRLLLPGIYTVSATAPG 393
++SV I H V +G+Y RL+L ++T S TAPG
Sbjct: 3898 IVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPG 3939
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,540,929
Number of Sequences: 37866
Number of extensions: 940368
Number of successful extensions: 2079
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2002
Number of HSP's gapped (non-prelim): 26
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.