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Search of human proteins with 4502173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502173 prostate specific antigen isoform 1 preproprotein
[Homo sapiens]
(261 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 552 e-157
gi|71834857 prostate specific antigen isoform 5 preproprotein [H... 449 e-126
gi|71834853 prostate specific antigen isoform 3 preproprotein [H... 442 e-124
gi|71834855 prostate specific antigen isoform 4 preproprotein [H... 442 e-124
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 435 e-122
gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens] 332 2e-91
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 332 2e-91
gi|11496281 kallikrein 13 precursor [Homo sapiens] 226 2e-59
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 218 4e-57
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 218 4e-57
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 218 4e-57
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 204 6e-53
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 204 8e-53
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 204 8e-53
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 204 8e-53
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 204 8e-53
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 203 1e-52
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 201 4e-52
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 199 2e-51
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 199 3e-51
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 196 2e-50
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 194 5e-50
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 192 3e-49
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 191 4e-49
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 191 4e-49
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 190 9e-49
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 187 1e-47
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 187 1e-47
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 181 4e-46
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 174 5e-44
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 552 bits (1422), Expect = e-157
Identities = 261/261 (100%), Positives = 261/261 (100%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
Query: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240
Query: 241 SLYTKVVHYRKWIKDTIVANP 261
SLYTKVVHYRKWIKDTIVANP
Sbjct: 241 SLYTKVVHYRKWIKDTIVANP 261
>gi|71834857 prostate specific antigen isoform 5 preproprotein [Homo
sapiens]
Length = 220
Score = 449 bits (1154), Expect = e-126
Identities = 220/261 (84%), Positives = 220/261 (84%), Gaps = 41/261 (15%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDS--- 117
Query: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
SIEPEEFLTPKKLQCVDLHVIS
Sbjct: 118 --------------------------------------SIEPEEFLTPKKLQCVDLHVIS 139
Query: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
Sbjct: 140 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 199
Query: 241 SLYTKVVHYRKWIKDTIVANP 261
SLYTKVVHYRKWIKDTIVANP
Sbjct: 200 SLYTKVVHYRKWIKDTIVANP 220
>gi|71834853 prostate specific antigen isoform 3 preproprotein [Homo
sapiens]
Length = 238
Score = 442 bits (1138), Expect = e-124
Identities = 210/210 (100%), Positives = 210/210 (100%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
Query: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 210
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS
Sbjct: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCS 210
>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
sapiens]
Length = 218
Score = 442 bits (1136), Expect = e-124
Identities = 217/261 (83%), Positives = 218/261 (83%), Gaps = 43/261 (16%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
LTAAHCIR +PGDDSSHD
Sbjct: 61 LTAAHCIR-------------------------------------------KPGDDSSHD 77
Query: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS
Sbjct: 78 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 137
Query: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240
NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP
Sbjct: 138 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 197
Query: 241 SLYTKVVHYRKWIKDTIVANP 261
SLYTKVVHYRKWIKDTIVANP
Sbjct: 198 SLYTKVVHYRKWIKDTIVANP 218
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 435 bits (1118), Expect = e-122
Identities = 201/261 (77%), Positives = 225/261 (86%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHD
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
Query: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERP 240
ND+CA+ + +KVT+FMLCAG WTGGK TC GDSGGPLVCNGVLQGITSWG EPCALPE+P
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKP 240
Query: 241 SLYTKVVHYRKWIKDTIVANP 261
++YTKVVHYRKWIKDTI ANP
Sbjct: 241 AVYTKVVHYRKWIKDTIAANP 261
>gi|50363237 kallikrein 2, prostatic isoform 2 [Homo sapiens]
Length = 223
Score = 332 bits (852), Expect = 2e-91
Identities = 155/209 (74%), Positives = 176/209 (84%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ + LSV GA PLI SRIVGGWECEKHSQPWQV V S G A CGGVLVHPQWV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
LTAAHC++ S + LGRH+LF PEDTGQ VSHSFPHPLY+MSLLK++ LRP +DSSHD
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120
Query: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVIS 180
LMLLRLSEPA++TD VKV+ LPTQEPALGTTCYASGWGSIEPEEFL P+ LQCV LH++S
Sbjct: 121 LMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLS 180
Query: 181 NDVCAQVHPQKVTKFMLCAGRWTGGKSTC 209
ND+CA+ + +KVT+FMLCAG WTGGK TC
Sbjct: 181 NDMCARAYSEKVTEFMLCAGLWTGGKDTC 209
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 332 bits (851), Expect = 2e-91
Identities = 158/261 (60%), Positives = 191/261 (73%), Gaps = 1/261 (0%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW V+ L LS+ GAAP I SRIVGGWECE+HSQPWQ + CGG+LVH QWV
Sbjct: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
LTAAHCI + + LGRH+LF E+T Q VS SFPHP ++MSLL+N + +D SHD
Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
Query: 121 LMLLRLSEPAE-LTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVI 179
LMLLRL+EPA+ +TDAVKV++LPT+EP +G+TC ASGWGSIEPE F P LQCVDL ++
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKIL 180
Query: 180 SNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPER 239
ND C + H QKVT FMLC G GGK TC GDSGGPL+C+GVLQG+TSWG PC P +
Sbjct: 181 PNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNK 240
Query: 240 PSLYTKVVHYRKWIKDTIVAN 260
PS+ +V+ Y KWI+DTI N
Sbjct: 241 PSVAVRVLSYVKWIEDTIAEN 261
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 226 bits (575), Expect = 2e-59
Identities = 110/232 (47%), Positives = 142/232 (61%), Gaps = 8/232 (3%)
Query: 27 GGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDT 86
GG+ C HSQPWQ + +GR +CGGVLVHP+WVLTAAHC++ + LG+H+L E
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 87 GQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEP 146
QV +V HS PHP Y S + HD+MLL L P +LT ++ + L
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHL-------NHDHDIMLLELQSPVQLTGYIQTLPLSHNNR 150
Query: 147 AL-GTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGG 205
GTTC SGWG+ + PK LQC ++ + S++ C QV+P K+T MLCAG GG
Sbjct: 151 LTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGG 210
Query: 206 KSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
K +C GDSGGPLVCN L GI SWG PC P+RP +YT+V Y WI++TI
Sbjct: 211 KDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 218 bits (555), Expect = 4e-57
Identities = 101/256 (39%), Positives = 154/256 (60%), Gaps = 11/256 (4%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124
HC++ + ++ LG+H+L E Q + SFPHP ++ SL P D +D+ML+
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114
Query: 125 RLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC 184
+++ P +T AV+ + L ++ GT+C SGWGS + P L+C ++ +I + C
Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174
Query: 185 AQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYT 244
+P +T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YT
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234
Query: 245 KVVHYRKWIKDTIVAN 260
KV Y WI++T+ N
Sbjct: 235 KVCKYVDWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 218 bits (555), Expect = 4e-57
Identities = 101/256 (39%), Positives = 154/256 (60%), Gaps = 11/256 (4%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 38 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 93
Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124
HC++ + ++ LG+H+L E Q + SFPHP ++ SL P D +D+ML+
Sbjct: 94 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 146
Query: 125 RLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC 184
+++ P +T AV+ + L ++ GT+C SGWGS + P L+C ++ +I + C
Sbjct: 147 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 206
Query: 185 AQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYT 244
+P +T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YT
Sbjct: 207 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 266
Query: 245 KVVHYRKWIKDTIVAN 260
KV Y WI++T+ N
Sbjct: 267 KVCKYVDWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 218 bits (555), Expect = 4e-57
Identities = 101/256 (39%), Positives = 154/256 (60%), Gaps = 11/256 (4%)
Query: 5 VVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAA 64
++ L L+ +G +RI+ G+EC+ HSQPWQ + + R +CG L+ P+W+LTAA
Sbjct: 6 LILLALATGLVGGE----TRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAA 61
Query: 65 HCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLL 124
HC++ + ++ LG+H+L E Q + SFPHP ++ SL P D +D+ML+
Sbjct: 62 HCLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSL-------PNKDHRNDIMLV 114
Query: 125 RLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVC 184
+++ P +T AV+ + L ++ GT+C SGWGS + P L+C ++ +I + C
Sbjct: 115 KMASPVSITWAVRPLTLSSRCVTAGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKC 174
Query: 185 AQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYT 244
+P +T M+CA GGK +C GDSGGPLVCN LQGI SWG +PCA+ +P +YT
Sbjct: 175 ENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYT 234
Query: 245 KVVHYRKWIKDTIVAN 260
KV Y WI++T+ N
Sbjct: 235 KVCKYVDWIQETMKNN 250
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 204 bits (519), Expect = 6e-53
Identities = 108/261 (41%), Positives = 152/261 (58%), Gaps = 18/261 (6%)
Query: 4 PVVFLTLSVTWIGAAPLILS-----RIVGGWECEKHSQPWQ--VLVASRGRAVCGGVLVH 56
P +FL L+ + A + S +I+GG C + SQPWQ +L R R +CGG L+
Sbjct: 15 PKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLS 74
Query: 57 PQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDD 116
QWV+TAAHC R + LG+H+L E T QV +V HP Y+ N
Sbjct: 75 GQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDN-------- 126
Query: 117 SSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDL 176
DLMLL+L +PA + AV+ +++ + GT+C SGWG+I P LQCV++
Sbjct: 127 ---DLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNI 183
Query: 177 HVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCAL 236
++ ++VC + +P+ +T M+CAG GGK +C GDSGGPLVC G LQG+ SWG E CAL
Sbjct: 184 NISPDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCAL 243
Query: 237 PERPSLYTKVVHYRKWIKDTI 257
P P +YT + YR WI++T+
Sbjct: 244 PGYPGVYTNLCKYRSWIEETM 264
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 8e-53
Identities = 103/240 (42%), Positives = 146/240 (60%), Gaps = 14/240 (5%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 82 HPEDTGQ-VFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140
++GQ +FQ S PHP Y PG S+DLML++L+ T V+ ++
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS---------HPGH--SNDLMLIKLNRRIRPTKDVRPIN 173
Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAG 200
+ + P+ GT C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
Query: 201 RWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
G+ +C GDSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 8e-53
Identities = 103/240 (42%), Positives = 146/240 (60%), Gaps = 14/240 (5%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 82 HPEDTGQ-VFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140
++GQ +FQ S PHP Y PG S+DLML++L+ T V+ ++
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS---------HPGH--SNDLMLIKLNRRIRPTKDVRPIN 173
Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAG 200
+ + P+ GT C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
Query: 201 RWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
G+ +C GDSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 204 bits (518), Expect = 8e-53
Identities = 103/240 (42%), Positives = 146/240 (60%), Gaps = 14/240 (5%)
Query: 23 SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81
SRI+ G +C+ H+QPWQ + R + CG VLVHPQW+LTAAHC + + LG +SL
Sbjct: 65 SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
Query: 82 HPEDTGQ-VFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140
++GQ +FQ S PHP Y PG S+DLML++L+ T V+ ++
Sbjct: 125 PVYESGQQMFQGVKSIPHPGYS---------HPGH--SNDLMLIKLNRRIRPTKDVRPIN 173
Query: 141 LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAG 200
+ + P+ GT C SGWG+ + + PK LQC+++ V+S C +P+++ M CAG
Sbjct: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
Query: 201 RWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
G+ +C GDSGGP+VCNG LQG+ SWG PCA P RP +YT + + KWI++TI AN
Sbjct: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 204 bits (518), Expect = 8e-53
Identities = 96/233 (41%), Positives = 139/233 (59%), Gaps = 7/233 (3%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
+R +G EC +SQPWQ + R CG L+ +W+LTAAHC + + LG H L+
Sbjct: 21 TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHHLWK 80
Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142
E Q+F+V+ FPHP ++ L N D + D+ML+RL A L+ AV+ ++L
Sbjct: 81 WEGPEQLFRVTDFFPHPGFNKDLSAN-------DHNDDIMLIRLPRQARLSPAVQPLNLS 133
Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202
+ G C SGWG++ + L P LQC ++ ++ N +C +P ++ MLCAG W
Sbjct: 134 QTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLW 193
Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKD 255
GG+ +C GDSGGPLVCNG L G+ S G+EPC+ P RP++YT V HY WI++
Sbjct: 194 EGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQE 246
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 203 bits (517), Expect = 1e-52
Identities = 103/250 (41%), Positives = 138/250 (55%), Gaps = 9/250 (3%)
Query: 8 LTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCI 67
L L W G + +++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC
Sbjct: 16 LLLGGAWAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 75
Query: 68 RNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLS 127
+ K + LG HSL + + Q V S PHP Y+ S + +D +HDLMLL+L
Sbjct: 76 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLR 127
Query: 128 EPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQV 187
+ A L VK + L G C SGWG++ P L C ++ + C
Sbjct: 128 DQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDA 187
Query: 188 HPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVV 247
+P ++T M+CAG + G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT +
Sbjct: 188 YPGQITDGMVCAGS-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNIC 246
Query: 248 HYRKWIKDTI 257
Y WIK I
Sbjct: 247 RYLDWIKKII 256
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 201 bits (512), Expect = 4e-52
Identities = 106/257 (41%), Positives = 145/257 (56%), Gaps = 13/257 (5%)
Query: 4 PVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63
P++ LT + A +IVGG+ CE++S P+QV + S G CGG L++ QWV++A
Sbjct: 3 PLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNS-GYHFCGGSLINEQWVVSA 61
Query: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLML 123
HC +++ + LG H++ E Q + HP YD L N D+ML
Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNN-----------DIML 110
Query: 124 LRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDV 183
++LS A + V + LPT PA GT C SGWG+ P +LQC+D V+S
Sbjct: 111 IKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAK 170
Query: 184 CAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLY 243
C +P K+T M C G GGK +C GDSGGP+VCNG LQG+ SWG + CA +P +Y
Sbjct: 171 CEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVY 229
Query: 244 TKVVHYRKWIKDTIVAN 260
TKV +Y KWIK+TI AN
Sbjct: 230 TKVYNYVKWIKNTIAAN 246
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 199 bits (507), Expect = 2e-51
Identities = 99/234 (42%), Positives = 133/234 (56%), Gaps = 9/234 (3%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC + K + LG HSL +
Sbjct: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNK 136
Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143
+ Q V S PHP Y+ S + +D +HDLMLL+L + A L VK + L
Sbjct: 137 DGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLAD 188
Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203
G C SGWG++ P L C ++ + C +P ++T M+CAG +
Sbjct: 189 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-S 247
Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK I
Sbjct: 248 KGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 199 bits (505), Expect = 3e-51
Identities = 108/270 (40%), Positives = 143/270 (52%), Gaps = 24/270 (8%)
Query: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
MW+ LTLS A +++ G EC HSQPWQV + RGR CG L+ P WV
Sbjct: 1 MWL---LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57
Query: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
L+AAHC + LG H+L + Q+ S PHP Y+ +N D
Sbjct: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRN-----------D 106
Query: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLT----------PKK 170
+MLLRL +PA L V+ LPT+ P G C SGWG + E T P
Sbjct: 107 IMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDT 166
Query: 171 LQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWG 230
L C ++ +IS+ C + +P ++T M+CAG G +C GDSGGPLVC G+LQGI SWG
Sbjct: 167 LHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWG 226
Query: 231 SEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
PC +P +YTKV HY +WI++T+ N
Sbjct: 227 DVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 196 bits (497), Expect = 2e-50
Identities = 105/255 (41%), Positives = 143/255 (56%), Gaps = 17/255 (6%)
Query: 10 LSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
L + ++GAA + +IVGG+ CE++S P+QV + S G CGG L+ QWV++AAH
Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAH 63
Query: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125
C + + + LG H++ E Q + HP Y+ L N D+ML++
Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIK 112
Query: 126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185
LS PA + V + LPT PA GT C SGWG+ P +L+C+D V++ C
Sbjct: 113 LSSPAVINARVSTISLPTAPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECK 172
Query: 186 QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTK 245
+P K+T M C G GGK +C DSGGP+VCNG LQG+ SWG CA RP +YTK
Sbjct: 173 ASYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTK 231
Query: 246 VVHYRKWIKDTIVAN 260
V +Y WIKDTI AN
Sbjct: 232 VYNYVDWIKDTIAAN 246
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 194 bits (494), Expect = 5e-50
Identities = 101/237 (42%), Positives = 135/237 (56%), Gaps = 13/237 (5%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+IVGG+ CE++S P+QV + S G CGG L+ QWV++AAHC + + + LG H++
Sbjct: 80 KIVGGYTCEENSLPYQVSLNS-GSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVL 138
Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143
E Q + HP Y+ L N D+ML++LS PA + V + LPT
Sbjct: 139 EGNEQFINAAKIIRHPKYNRDTLDN-----------DIMLIKLSSPAVINARVSTISLPT 187
Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203
PA GT C SGWG+ P +L+C+D V++ C +P K+T M C G
Sbjct: 188 APPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLE 247
Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
GGK +C DSGGP+VCNG LQG+ SWG CA RP +YTKV +Y WIKDTI AN
Sbjct: 248 GGKDSCQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 192 bits (487), Expect = 3e-49
Identities = 96/239 (40%), Positives = 137/239 (57%), Gaps = 14/239 (5%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
S+I+ G +C HSQPWQ + C GVLVHPQWVL+AAHC +N I LG HSL
Sbjct: 29 SQIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEA 88
Query: 83 PEDTG-QVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDL 141
++ G Q+ + S S HP Y+ LL N DLML++L E +D ++ + +
Sbjct: 89 DQEPGSQMVEASLSVRHPEYNRPLLAN-----------DLMLIKLDESVSESDTIRSISI 137
Query: 142 PTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGR 201
+Q P G +C SGWG + P LQCV++ V+S +VC++++ M CAG
Sbjct: 138 ASQCPTAGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGG 195
Query: 202 WTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
K +C+GDSGGPL+CNG LQG+ S+G PC P +YT + + +WI+ T+ A+
Sbjct: 196 GHDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 191 bits (486), Expect = 4e-49
Identities = 93/237 (39%), Positives = 137/237 (57%), Gaps = 13/237 (5%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
+++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L
Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQ 79
Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142
E + + V + HP YD + D+MLLRL+ PA+L++ ++ + L
Sbjct: 80 RESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPLE 128
Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202
A T+C+ GWG +F P +QC +H++S + C +P ++T+ MLCAG
Sbjct: 129 RDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDE 186
Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259
GK +C GDSGGPLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A
Sbjct: 187 KYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 191 bits (486), Expect = 4e-49
Identities = 93/237 (39%), Positives = 137/237 (57%), Gaps = 13/237 (5%)
Query: 23 SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFH 82
+++V G C+K S P+Q + + G +CGGVL+HP WVLTAAHC + + LG+H+L
Sbjct: 20 NKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLRQ 79
Query: 83 PEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLP 142
E + + V + HP YD + D+MLLRL+ PA+L++ ++ + L
Sbjct: 80 RESSQEQSSVVRAVIHPDYDAA-----------SHDQDIMLLRLARPAKLSELIQPLPLE 128
Query: 143 TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRW 202
A T+C+ GWG +F P +QC +H++S + C +P ++T+ MLCAG
Sbjct: 129 RDCSANTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDE 186
Query: 203 TGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVA 259
GK +C GDSGGPLVC L+G+ SWG+ PC E+P +YT V Y WI+ TI A
Sbjct: 187 KYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 190 bits (483), Expect = 9e-49
Identities = 106/257 (41%), Positives = 142/257 (55%), Gaps = 17/257 (6%)
Query: 8 LTLSVTWIGAAPLIL----SRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTA 63
L L +T++ AA +IVGG+ CE++S P+QV + S G CGG L+ QWV++A
Sbjct: 3 LLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNS-GYHFCGGSLISEQWVVSA 61
Query: 64 AHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLML 123
HC +++ + LG H++ E Q + HP Y+ L N D++L
Sbjct: 62 GHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDN-----------DILL 110
Query: 124 LRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDV 183
++LS PA + V + LPT PA GT SGWG+ P +LQC+D V+S
Sbjct: 111 IKLSSPAVINSRVSAISLPTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAE 170
Query: 184 CAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLY 243
C +P K+T M C G GGK +C GDSGGP+V NG LQGI SWG CA RP +Y
Sbjct: 171 CEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVY 229
Query: 244 TKVVHYRKWIKDTIVAN 260
TKV +Y WIKDTI AN
Sbjct: 230 TKVYNYVDWIKDTIAAN 246
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 187 bits (474), Expect = 1e-47
Identities = 98/234 (41%), Positives = 132/234 (56%), Gaps = 13/234 (5%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L
Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86
Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143
+ Q + S SF HP Y N DLML++L+ A L+ VK + LP+
Sbjct: 87 DRRAQRIKASKSFRHPGYSTQTHVN-----------DLMLVKLNSQARLSSMVKKVRLPS 135
Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203
+ GTTC SGWG+ + P L CVD+ +IS C +V+ + MLCAG
Sbjct: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195
Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
K+ C+GDSGGPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 187 bits (474), Expect = 1e-47
Identities = 98/234 (41%), Positives = 132/234 (56%), Gaps = 13/234 (5%)
Query: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
+I+ G C + S PWQV + S + CGGVLV+ +WVLTAAHC N+ + LG +L
Sbjct: 29 KIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTL--G 86
Query: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143
+ Q + S SF HP Y N DLML++L+ A L+ VK + LP+
Sbjct: 87 DRRAQRIKASKSFRHPGYSTQTHVN-----------DLMLVKLNSQARLSSMVKKVRLPS 135
Query: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203
+ GTTC SGWG+ + P L CVD+ +IS C +V+ + MLCAG
Sbjct: 136 RCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPD 195
Query: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
K+ C+GDSGGPLVC G LQG+ SWG+ PC P P +YT+V + KWI DT+
Sbjct: 196 SKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 249
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 181 bits (460), Expect = 4e-46
Identities = 101/250 (40%), Positives = 134/250 (53%), Gaps = 13/250 (5%)
Query: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
+FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH
Sbjct: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125
C ++ + LG HSL + T Q+ S HP Y L HDL LLR
Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY---------LGASTSHEHDLRLLR 113
Query: 126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185
L P +T +V+ + LP GT C+ SGWG P LQC++L ++S+ C
Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173
Query: 186 QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYT 244
V+P ++T M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT
Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232
Query: 245 KVVHYRKWIK 254
+ Y WI+
Sbjct: 233 YICKYVDWIR 242
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 174 bits (442), Expect = 5e-44
Identities = 98/242 (40%), Positives = 130/242 (53%), Gaps = 13/242 (5%)
Query: 6 VFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAH 65
+FL L V +G + +I G EC ++SQPWQV + CGGVL+ +WVLTAAH
Sbjct: 5 IFLLLCV--LGLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 66 CIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLR 125
C ++ + LG HSL + T Q+ S HP Y L HDL LLR
Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGY---------LGASTSHEHDLRLLR 113
Query: 126 LSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCA 185
L P +T +V+ + LP GT C+ SGWG P LQC++L ++S+ C
Sbjct: 114 LRLPVRVTSSVQPLPLPNDCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCH 173
Query: 186 QVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGS-EPCALPERPSLYT 244
V+P ++T M+CAG G+ C GDSGGPLVC GVLQG+ SWGS PC P +YT
Sbjct: 174 GVYPGRITSNMVCAG-GVPGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYT 232
Query: 245 KV 246
+
Sbjct: 233 YI 234
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,535,233
Number of Sequences: 37866
Number of extensions: 541537
Number of successful extensions: 1716
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 168
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1111
Number of HSP's gapped (non-prelim): 209
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.