Search of human proteins with 126273546

Search of human proteins with 126273546

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|126273546 islet-specific glucose-6-phosphatase-related
protein isoform 2 [Homo sapiens]
         (154 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|126273546 islet-specific glucose-6-phosphatase-related protei...   339   5e-94
gi|10863975 islet-specific glucose-6-phosphatase-related protein...   324   2e-89
gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens]    164   2e-41
gi|24308434 glucose-6-phosphatase catalytic subunit 3 [Homo sapi...   115   2e-26
gi|55770876 notch4 preproprotein [Homo sapiens]                        31   0.48 
gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens]       29   1.4  
gi|38788380 dehydrogenase E1 and transketolase domain containing...    27   5.3  
gi|118421087 monooxygenase, DBH-like 1 isoform 2 [Homo sapiens]        27   6.9  
gi|40255245 G protein-coupled receptor 51 [Homo sapiens]               27   9.1  

>gi|126273546 islet-specific glucose-6-phosphatase-related protein
           isoform 2 [Homo sapiens]
          Length = 154

 Score =  339 bits (870), Expect = 5e-94
 Identities = 154/154 (100%), Positives = 154/154 (100%)

Query: 1   MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV 60
           MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV
Sbjct: 1   MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV 60

Query: 61  AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS 120
           AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS
Sbjct: 61  AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS 120

Query: 121 CVWYVMVTAALSHTVCGMDKFSITLHRHAGGRGL 154
           CVWYVMVTAALSHTVCGMDKFSITLHRHAGGRGL
Sbjct: 121 CVWYVMVTAALSHTVCGMDKFSITLHRHAGGRGL 154


>gi|10863975 islet-specific glucose-6-phosphatase-related protein
           isoform 1 [Homo sapiens]
          Length = 355

 Score =  324 bits (831), Expect = 2e-89
 Identities = 147/147 (100%), Positives = 147/147 (100%)

Query: 1   MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV 60
           MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV
Sbjct: 1   MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV 60

Query: 61  AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS 120
           AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS
Sbjct: 61  AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS 120

Query: 121 CVWYVMVTAALSHTVCGMDKFSITLHR 147
           CVWYVMVTAALSHTVCGMDKFSITLHR
Sbjct: 121 CVWYVMVTAALSHTVCGMDKFSITLHR 147


>gi|4557599 glucose-6-phosphatase, catalytic subunit [Homo sapiens]
          Length = 357

 Score =  164 bits (416), Expect = 2e-41
 Identities = 73/132 (55%), Positives = 94/132 (71%)

Query: 1   MDFLHRNGVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWV 60
           M+ LH  G+    +LQ +Y+    +   +S + D RN F++ FP+ F   + VG K++WV
Sbjct: 5   MNVLHDFGIQSTHYLQVNYQDSQDWFILVSVIADLRNAFYVLFPIWFHLQEAVGIKLLWV 64

Query: 61  AVIGDWLNLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGAS 120
           AVIGDWLNL+FKWILFG RPYWWV +T  Y N S P ++QFP TCETGPGSPSGHAMG +
Sbjct: 65  AVIGDWLNLVFKWILFGQRPYWWVLDTDYYSNTSVPLIKQFPVTCETGPGSPSGHAMGTA 124

Query: 121 CVWYVMVTAALS 132
            V+YVMVT+ LS
Sbjct: 125 GVYYVMVTSTLS 136


>gi|24308434 glucose-6-phosphatase catalytic subunit 3 [Homo
           sapiens]
          Length = 346

 Score =  115 bits (287), Expect = 2e-26
 Identities = 51/125 (40%), Positives = 79/125 (63%), Gaps = 1/125 (0%)

Query: 8   GVLIIQHLQKDYRAYYTFLNFMSNVGDPRNIFFIYFPLCFQFNQTVGTKMIWVAVIGDWL 67
           G++I + LQ           +++ +GDP+ +F  YFP  +  ++ VG  ++W+++I +WL
Sbjct: 8   GIVIAEALQNQLAWLENVWLWITFLGDPKILFLFYFPAAYYASRRVGIAVLWISLITEWL 67

Query: 68  NLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMV 127
           NLIFKW LFG RP+WWV E+  Y + +   + QFP++CETGPGSPSGH M      + ++
Sbjct: 68  NLIFKWFLFGDRPFWWVHESGYY-SQAPAQVHQFPSSCETGPGSPSGHCMITGAALWPIM 126

Query: 128 TAALS 132
           TA  S
Sbjct: 127 TALSS 131


>gi|55770876 notch4 preproprotein [Homo sapiens]
          Length = 2003

 Score = 30.8 bits (68), Expect = 0.48
 Identities = 19/47 (40%), Positives = 21/47 (44%), Gaps = 4/47 (8%)

Query: 68   NLIFKWILFGHRPYWWVQETQIYPNHSSPCLEQFPTTCETGPGSPSG 114
            N  +   L GH   W   E +I P HS PC      TCE   GSP G
Sbjct: 1028 NAFYCQCLPGHTGQWC--EVEIDPCHSQPCFH--GGTCEATAGSPLG 1070


>gi|23510289 sphingosine-1-phosphate phosphotase 2 [Homo sapiens]
          Length = 399

 Score = 29.3 bits (64), Expect = 1.4
 Identities = 24/105 (22%), Positives = 48/105 (45%), Gaps = 13/105 (12%)

Query: 36  RNIFFIYFPLCFQFNQTVGTKMIWVAV-------IGDWLN--LIFKWILFGHRPYWWVQE 86
           +N F+ Y    FQF+  +G ++ ++         I  +L+  LI  W+L  +      ++
Sbjct: 82  KNYFYYYL---FQFSAALGQEVFYITFLPFTHWNIDPYLSRRLIIIWVLVMYIGQV-AKD 137

Query: 87  TQIYPNHSSPCLEQFPTTCETGPGSPSGHAMGASCVWYVMVTAAL 131
              +P  SSP + +         G PS HAM A+ + + ++ + +
Sbjct: 138 VLKWPRPSSPPVVKLEKRLIAEYGMPSTHAMAATAIAFTLLISTM 182


>gi|38788380 dehydrogenase E1 and transketolase domain containing 1
           [Homo sapiens]
          Length = 919

 Score = 27.3 bits (59), Expect = 5.3
 Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 13/70 (18%)

Query: 58  IWVAVIGDWLN---LIFKWILFGHRPYWWVQETQIY----------PNHSSPCLEQFPTT 104
           +W A  GD+ N   +IF   + G    W +Q   +           P+HSS  +E+F   
Sbjct: 660 LWEAQFGDFFNGAQIIFDTFISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQM 719

Query: 105 CETGPGSPSG 114
           C++      G
Sbjct: 720 CDSAEEGVDG 729


>gi|118421087 monooxygenase, DBH-like 1 isoform 2 [Homo sapiens]
          Length = 613

 Score = 26.9 bits (58), Expect = 6.9
 Identities = 14/46 (30%), Positives = 21/46 (45%), Gaps = 1/46 (2%)

Query: 109 PGSPSGHAMGASCVWYVMVTAALSHTVCGMDKFSITLHRHAGGRGL 154
           PG P   + G  C    +  A  +    G+  F++ LH H  GRG+
Sbjct: 353 PGMPEFQSEG-HCTLECLEEALEAEKPSGIHVFAVLLHAHLAGRGI 397


>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
          Length = 941

 Score = 26.6 bits (57), Expect = 9.1
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 5/55 (9%)

Query: 48  QFNQTVGTKMIWVAVIGDWLNLIFKWILFG-HRPYWWVQ-ETQIYPNHSSPCLEQ 100
           QF+Q +  K+   A   +     ++WI+ G + P WW Q  T+    +SS CL +
Sbjct: 254 QFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEA---NSSRCLRK 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.142    0.501 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,899,412
Number of Sequences: 37866
Number of extensions: 302183
Number of successful extensions: 864
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 859
Number of HSP's gapped (non-prelim): 10
length of query: 154
length of database: 18,247,518
effective HSP length: 93
effective length of query: 61
effective length of database: 14,725,980
effective search space: 898284780
effective search space used: 898284780
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.