Guide to the Human Genome
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Search of human proteins with 41393593

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41393593 aarF domain containing kinase 5 [Homo sapiens]
         (580 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41393593 aarF domain containing kinase 5 [Homo sapiens]           1163   0.0  
gi|40254938 aarF domain containing kinase 1 isoform a [Homo sapi...   301   1e-81
gi|217035081 aarF domain containing kinase 1 isoform b [Homo sap...   244   2e-64
gi|34147522 chaperone, ABC1 activity of bc1 complex like precurs...    79   1e-14
gi|217416386 aarF domain containing kinase 4 isoform b [Homo sap...    77   3e-14
gi|27363457 aarF domain containing kinase 4 isoform a [Homo sapi...    77   3e-14
gi|32261307 aarF domain containing kinase 2 [Homo sapiens]             54   5e-07
gi|103471999 serine/threonine kinase 3 [Homo sapiens]                  32   1.2  
gi|7019547 TANK-binding kinase 1 [Homo sapiens]                        31   2.7  
gi|7661946 IKK-related kinase epsilon [Homo sapiens]                   31   3.6  
gi|21735544 mitogen-activated protein kinase kinase 7 [Homo sapi...    30   6.1  
gi|165905601 proline-serine-threonine phosphatase interacting pr...    30   8.0  
gi|5454096 serine/threonine kinase 4 [Homo sapiens]                    30   8.0  

>gi|41393593 aarF domain containing kinase 5 [Homo sapiens]
          Length = 580

 Score = 1163 bits (3008), Expect = 0.0
 Identities = 580/580 (100%), Positives = 580/580 (100%)

Query: 1   MWRPVQLCHFHSALLHRRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPL 60
           MWRPVQLCHFHSALLHRRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPL
Sbjct: 1   MWRPVQLCHFHSALLHRRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPL 60

Query: 61  LLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYL 120
           LLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYL
Sbjct: 61  LLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYL 120

Query: 121 EVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQ 180
           EVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQ
Sbjct: 121 EVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQ 180

Query: 181 EVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDG 240
           EVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDG
Sbjct: 181 EVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDG 240

Query: 241 DIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVV 300
           DIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVV
Sbjct: 241 DIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVV 300

Query: 301 PRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSD 360
           PRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSD
Sbjct: 301 PRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSD 360

Query: 361 PHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALG 420
           PHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALG
Sbjct: 361 PHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALG 420

Query: 421 VQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLV 480
           VQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLV
Sbjct: 421 VQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLV 480

Query: 481 LRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLK 540
           LRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLK
Sbjct: 481 LRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLK 540

Query: 541 FEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET 580
           FEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET
Sbjct: 541 FEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET 580


>gi|40254938 aarF domain containing kinase 1 isoform a [Homo
           sapiens]
          Length = 523

 Score =  301 bits (771), Expect = 1e-81
 Identities = 192/496 (38%), Positives = 279/496 (56%), Gaps = 35/496 (7%)

Query: 83  GMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNG 142
           G  R GR++     IS DY      V  G EE    YL++ S  H R+A  L     +N 
Sbjct: 35  GAVRVGRAVATTAVISYDYLTSLKSVPYGSEE----YLQLRSKVHLRSARRLCELCCANR 90

Query: 143 GLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFD 202
           G ++K+GQ L + ++LLP EYT TL+VL  +A +   QE+ ++  ED     H+LFQ FD
Sbjct: 91  GTFIKVGQHLGALDYLLPEEYTSTLKVLHSQAPQSSMQEIRQVIREDLGKEIHDLFQSFD 150

Query: 203 YQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFS 262
             P+  ASLAQVH+A LHDG +VAVKVQ+  +R +   DI  +E+L+  V+ + P F F 
Sbjct: 151 DTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEVLVLAVKQLFPEFEFM 210

Query: 263 WVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCK 322
           W++ + K  L  ELDF NEGRNAE+ ++ L HF ++ VPR+HWD S++RVL  +F  G +
Sbjct: 211 WLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLLMEFVDGGQ 270

Query: 323 VNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGP-DGKAELVLL 381
           VND + +    + V++I+  L K ++E IF  GF+H DPHPGNVLVRK P  GKAE+VLL
Sbjct: 271 VNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGTGKAEIVLL 330

Query: 382 DHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQD-YLLFAEMLMQRPVRLGQ 440
           DHGLYQ L E+ R   C LW+++I  D   ++ ++  LG  D Y LFA ML  R      
Sbjct: 331 DHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRLGAGDLYPLFACMLTARS----- 385

Query: 441 LWGS--HLLSREEAAYMVDM-----ARERFEAVMAVLRELPRPMLLVLRNINTVRAINVA 493
            W S    +S+       D+     A      +  +L  +PR MLL+L+  + +R I  A
Sbjct: 386 -WDSVNRGISQAPVTATEDLEIRNNAANYLPQISHLLNHVPRQMLLILKTNDLLRGIEAA 444

Query: 494 LG--APVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKV-------VWEMLKFEVA 544
           LG  A    +  M++  +R     A A ++     S  R  ++       +W++   E+ 
Sbjct: 445 LGTRASASSFLNMSRCCIR-----ALAEHKKKNTCSFFRRTQISFSEAFNLWQINLHELI 499

Query: 545 LRLE--TLAMRLTALL 558
           LR++   LA R+ AL+
Sbjct: 500 LRVKGLKLADRVLALI 515


>gi|217035081 aarF domain containing kinase 1 isoform b [Homo
           sapiens]
          Length = 455

 Score =  244 bits (622), Expect = 2e-64
 Identities = 152/384 (39%), Positives = 221/384 (57%), Gaps = 31/384 (8%)

Query: 195 HELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEV 254
           H+LFQ FD  P+  ASLAQVH+A LHDG +VAVKVQ+  +R +   DI  +E+L+  V+ 
Sbjct: 75  HDLFQSFDDTPLGTASLAQVHKAVLHDGRTVAVKVQHPKVRAQSSKDILLMEVLVLAVKQ 134

Query: 255 MHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLT 314
           + P F F W++ + K  L  ELDF NEGRNAE+ ++ L HF ++ VPR+HWD S++RVL 
Sbjct: 135 LFPEFEFMWLVDEAKKNLPLELDFLNEGRNAEKVSQMLRHFDFLKVPRIHWDLSTERVLL 194

Query: 315 ADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGP-D 373
            +F  G +VND + +    + V++I+  L K ++E IF  GF+H DPHPGNVLVRK P  
Sbjct: 195 MEFVDGGQVNDRDYMERNKIDVNEISRHLGKMYSEMIFVNGFVHCDPHPGNVLVRKHPGT 254

Query: 374 GKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQD-YLLFAEMLM 432
           GKAE+VLLDHGLYQ L E+ R   C LW+++I  D   ++ ++  LG  D Y LFA ML 
Sbjct: 255 GKAEIVLLDHGLYQMLTEEFRLNYCHLWQSLIWTDMKRVKEYSQRLGAGDLYPLFACMLT 314

Query: 433 QRPVRLGQLWGS--HLLSREEAAYMVDM-----ARERFEAVMAVLRELPRPMLLVLRNIN 485
            R       W S    +S+       D+     A      +  +L  +PR MLL+L+  +
Sbjct: 315 ARS------WDSVNRGISQAPVTATEDLEIRNNAANYLPQISHLLNHVPRQMLLILKTND 368

Query: 486 TVRAINVALG--APVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKV-------VW 536
            +R I  ALG  A    +  M++  +R     A A ++     S  R  ++       +W
Sbjct: 369 LLRGIEAALGTRASASSFLNMSRCCIR-----ALAEHKKKNTCSFFRRTQISFSEAFNLW 423

Query: 537 EMLKFEVALRLE--TLAMRLTALL 558
           ++   E+ LR++   LA R+ AL+
Sbjct: 424 QINLHELILRVKGLKLADRVLALI 447


>gi|34147522 chaperone, ABC1 activity of bc1 complex like precursor
           [Homo sapiens]
          Length = 647

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 76/349 (21%), Positives = 146/349 (41%), Gaps = 15/349 (4%)

Query: 71  AREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSP-GYLEVMSAC--- 126
           ARE++     +  +  FG     GL + L +     V  + +    P G   V+ +    
Sbjct: 201 ARERKVPVTRIGRLANFG-----GLAVGLGFGALAEVAKKSLRSEDPSGKKAVLGSSPFL 255

Query: 127 HQRAADALVAGAISNGGLYVKLGQGLC-SFNHLLPPEYTRTLRVLEDRALKRGFQEVDEL 185
            +  A+ +V       G  +KLGQ L    +  + P   +    +   A     +++ + 
Sbjct: 256 SEANAERIVRTLCKVRGAALKLGQMLSIQDDAFINPHLAKIFERVRQSADFMPLKQMMKT 315

Query: 186 FLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTL 245
              D      +  + F+ +P AAAS+ QVH A++  G  VA+K+QY  +    + D++ L
Sbjct: 316 LNNDLGPNWRDKLEYFEERPFAAASIGQVHLARMKGGREVAMKIQYPGVAQSINSDVNNL 375

Query: 246 ELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHW 305
             +L +  ++        ++  L+  LA E D++ E   A +    L   P+  VP +  
Sbjct: 376 MAVLNMSNMLPEGLFPEHLIDVLRRELALECDYQREAACARKFRDLLKGHPFFYVPEIVD 435

Query: 306 DKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGN 365
           +  S  VLT +  +G  ++  E +  +    ++I   ++     ++F   F+ +DP+  N
Sbjct: 436 ELCSPHVLTTELVSGFPLDQAEGLSQE--IRNEICYNILVLCLRELFEFHFMQTDPNWSN 493

Query: 366 VLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRA 414
                    + ++ LLD G  +  +        Q+ RA   RD   +RA
Sbjct: 494 FFY---DPQQHKVALLDFGATREYDRSFTDLYIQIIRAAADRDRETVRA 539


>gi|217416386 aarF domain containing kinase 4 isoform b [Homo
           sapiens]
          Length = 503

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 55/180 (30%), Positives = 87/180 (48%), Gaps = 5/180 (2%)

Query: 205 PIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWV 264
           P AAAS+ QVH+  L DGT VAVK+QY  +      D+  L  +L++   +         
Sbjct: 173 PFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQS 232

Query: 265 LQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVN 324
           LQ L+  LA E D+  E   A+   + LA+ P+  VP V  +  + RVL  +   G  ++
Sbjct: 233 LQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLD 292

Query: 325 DVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHG 384
             + + SQ L  + I  +L+     ++F   F+ +DP+  N L         ++ LLD G
Sbjct: 293 QCQGL-SQDLR-NQICFQLLTLCLRELFEFRFMQTDPNWANFLY---DASSHQVTLLDFG 347


>gi|27363457 aarF domain containing kinase 4 isoform a [Homo
           sapiens]
          Length = 544

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 55/180 (30%), Positives = 87/180 (48%), Gaps = 5/180 (2%)

Query: 205 PIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWV 264
           P AAAS+ QVH+  L DGT VAVK+QY  +      D+  L  +L++   +         
Sbjct: 214 PFAAASIGQVHQGLLRDGTEVAVKIQYPGIAQSIQSDVQNLLAVLKMSAALPAGLFAEQS 273

Query: 265 LQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVN 324
           LQ L+  LA E D+  E   A+   + LA+ P+  VP V  +  + RVL  +   G  ++
Sbjct: 274 LQALQQELAWECDYRREAACAQNFRQLLANDPFFRVPAVVKELCTTRVLGMELAGGVPLD 333

Query: 325 DVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHG 384
             + + SQ L  + I  +L+     ++F   F+ +DP+  N L         ++ LLD G
Sbjct: 334 QCQGL-SQDLR-NQICFQLLTLCLRELFEFRFMQTDPNWANFLY---DASSHQVTLLDFG 388


>gi|32261307 aarF domain containing kinase 2 [Homo sapiens]
          Length = 626

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 69/289 (23%), Positives = 125/289 (43%), Gaps = 22/289 (7%)

Query: 207 AAASLAQV--HRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSW- 263
           A  S AQV  H+ +  +  SVAVKV +  L  +   D+  +++  R++ V+    G  W 
Sbjct: 288 AGVSRAQVPGHQPEATNLISVAVKVLHPGLLAQVHMDLLLMKIGSRVLGVLP---GIKWL 344

Query: 264 ----VLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCA 319
               ++++ +  + Q++D   E +N E       +   V  P       ++ VL   +  
Sbjct: 345 SLPEIVEEFEKLMVQQIDLRYEAQNLEHFQVNFRNVKAVKFPTPLRPFVTREVLVETYEE 404

Query: 320 GCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVR--KGPDGKAE 377
              V+  +           IA   I    + IF   F+H+D HPGN+LV+   G     E
Sbjct: 405 SVPVSSYQQAGIPVDLKRKIARLGINMLLKMIFVDNFVHADLHPGNILVQGANGLSSSQE 464

Query: 378 LVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDY-LLFAEMLMQRPV 436
             L    +   L     ++LC L R ++L  DA + A   A  ++++  +F  ++M +  
Sbjct: 465 AQLQQADICDTLVVAVPSSLCPL-RLVLL--DAGIVAELQAPDLRNFRAVFMAVVMGQGQ 521

Query: 437 RLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNIN 485
           R+ +L    +L    A+   D+  E F+  MA+L    R   + L  ++
Sbjct: 522 RVAEL----ILHHARASECRDV--EGFKTEMAMLVTQARKNTITLEKLH 564


>gi|103471999 serine/threonine kinase 3 [Homo sapiens]
          Length = 491

 Score = 32.3 bits (72), Expect = 1.2
 Identities = 24/86 (27%), Positives = 45/86 (52%), Gaps = 6/86 (6%)

Query: 296 PYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTG 355
           PYVV     + K++   +  ++C    V+D+  +R++ L   +IA  ++K+  + + Y  
Sbjct: 80  PYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIA-TILKSTLKGLEYLH 138

Query: 356 F---IHSDPHPGNVLVRKGPDGKAEL 378
           F   IH D   GN+L+    +G A+L
Sbjct: 139 FMRKIHRDIKAGNILL--NTEGHAKL 162


>gi|7019547 TANK-binding kinase 1 [Homo sapiens]
          Length = 729

 Score = 31.2 bits (69), Expect = 2.7
 Identities = 14/40 (35%), Positives = 23/40 (57%)

Query: 355 GFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDR 394
           G +H D  PGN++   G DG++   L D G  + LE+ ++
Sbjct: 130 GIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQ 169


>gi|7661946 IKK-related kinase epsilon [Homo sapiens]
          Length = 716

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 4/91 (4%)

Query: 308 SSKRVLTADFCAGCKVNDVEAIRSQGLAVHD----IAEKLIKAFAEQIFYTGFIHSDPHP 363
           S ++VL  ++C+   +  V         + +    +  + + A    +   G +H D  P
Sbjct: 79  SRQKVLVMEYCSSGSLLSVLESPENAFGLPEDEFLVVLRCVVAGMNHLRENGIVHRDIKP 138

Query: 364 GNVLVRKGPDGKAELVLLDHGLYQFLEEKDR 394
           GN++   G +G++   L D G  + L++ ++
Sbjct: 139 GNIMRLVGEEGQSIYKLTDFGAARELDDDEK 169


>gi|21735544 mitogen-activated protein kinase kinase 7 [Homo
           sapiens]
          Length = 419

 Score = 30.0 bits (66), Expect = 6.1
 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 11/81 (13%)

Query: 330 RSQGLAVHDIAEKLIKAFAEQIFYT----GFIHSDPHPGNVLVRKGPDGKAELVLLDHGL 385
           R QG     I  K+  A  + ++Y     G IH D  P N+L+    D + ++ L D G+
Sbjct: 209 RMQGPIPERILGKMTVAIVKALYYLKEKHGVIHRDVKPSNILL----DERGQIKLCDFGI 264

Query: 386 YQFL---EEKDRAALCQLWRA 403
              L   + K R+A C  + A
Sbjct: 265 SGRLVDSKAKTRSAGCAAYMA 285


>gi|165905601 proline-serine-threonine phosphatase interacting
           protein 2 [Homo sapiens]
          Length = 334

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 16/44 (36%), Positives = 24/44 (54%)

Query: 367 LVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDA 410
           L RK P G++E+  L   L  F ++ D  A C +  A  LR++A
Sbjct: 59  LSRKKPCGQSEINTLKRALEVFKQQVDNVAQCHIQLAQSLREEA 102


>gi|5454096 serine/threonine kinase 4 [Homo sapiens]
          Length = 487

 Score = 29.6 bits (65), Expect = 8.0
 Identities = 22/85 (25%), Positives = 41/85 (48%), Gaps = 4/85 (4%)

Query: 296 PYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAF--AEQIFY 353
           P+VV     + K++   +  ++C    V+D+  +R++ L   +IA  L       E + +
Sbjct: 83  PHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHF 142

Query: 354 TGFIHSDPHPGNVLVRKGPDGKAEL 378
              IH D   GN+L+    +G A+L
Sbjct: 143 MRKIHRDIKAGNILL--NTEGHAKL 165


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,331,072
Number of Sequences: 37866
Number of extensions: 938004
Number of successful extensions: 2481
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2465
Number of HSP's gapped (non-prelim): 16
length of query: 580
length of database: 18,247,518
effective HSP length: 108
effective length of query: 472
effective length of database: 14,157,990
effective search space: 6682571280
effective search space used: 6682571280
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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