Search of human proteins with 41152086

Search of human proteins with 41152086

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
         (376 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   748   0.0  
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   501   e-142
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   501   e-142
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   474   e-134
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   368   e-102
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   346   2e-95
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   343   1e-94
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   343   1e-94
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   337   1e-92
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o...   334   7e-92
gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (...   322   3e-88
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o...   317   1e-86
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   312   4e-85
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (...   306   2e-83
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ...   259   2e-69
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (...   246   2e-65
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o...   246   2e-65
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   241   6e-64
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   229   2e-60
gi|170295807 neuroserpin precursor [Homo sapiens]                     223   2e-58
gi|4826904 neuroserpin precursor [Homo sapiens]                       223   2e-58
gi|211904156 plasminogen activator inhibitor type 1, member 2 is...   191   7e-49
gi|211904154 plasminogen activator inhibitor type 1, member 2 is...   191   7e-49
gi|211904152 plasminogen activator inhibitor type 1, member 2 is...   191   7e-49
gi|24307907 plasminogen activator inhibitor type 1, member 2 iso...   189   3e-48
gi|73858564 corticosteroid binding globulin precursor [Homo sapi...   187   1e-47
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   184   9e-47
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   184   9e-47
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   184   9e-47
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   184   9e-47

>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  748 bits (1932), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN 60
           MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN
Sbjct: 1   MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN 60

Query: 61  KSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEE 120
           KSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEE
Sbjct: 61  KSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEE 120

Query: 121 LDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKE 180
           LDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKE
Sbjct: 121 LDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKE 180

Query: 181 NTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTD 240
           NTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTD
Sbjct: 181 NTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTD 240

Query: 241 LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKA 300
           LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKA
Sbjct: 241 LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKA 300

Query: 301 DFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQ 360
           DFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQ
Sbjct: 301 DFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQ 360

Query: 361 HSKTNGILFCGRFSSP 376
           HSKTNGILFCGRFSSP
Sbjct: 361 HSKTNGILFCGRFSSP 376


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  501 bits (1291), Expect = e-142
 Identities = 253/378 (66%), Positives = 303/378 (80%), Gaps = 6/378 (1%)

Query: 1   MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           MD L EANGTFA++L K LG+ DNS+NVFFSPMS+S ALAMV+MGAKG+TAAQM+Q L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 60  NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
            K G   DIH+GFQSLL+EVN+TGTQYLLR ANRLFGEK+CDFL  F++ CQKFYQAE+E
Sbjct: 61  YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117

Query: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
           EL F    E+ RKHIN WVAEKTEGKI+E+L  G+VDPLT+LVLVNA+YF+G W+EQFD+
Sbjct: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177

Query: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 239
           + T   LFK ++ E+K VQMMFK++ FK  Y  E+ TQ+L LPYV +EL+M+I+LPD+ T
Sbjct: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236

Query: 240 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 299
           DL  VEK LTYEKF  WT  + + + +V+V LPR KLEESYD+E  LR LGM DAF+  K
Sbjct: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296

Query: 300 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF 358
           ADFSGMS + ++ LSKV HK FVEVNEEGTEAAAATA +   RC+R  PRFCADHPFLFF
Sbjct: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356

Query: 359 IQHSKTNGILFCGRFSSP 376
           I+H KTN ILFCGRFSSP
Sbjct: 357 IRHHKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  501 bits (1291), Expect = e-142
 Identities = 253/378 (66%), Positives = 303/378 (80%), Gaps = 6/378 (1%)

Query: 1   MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           MD L EANGTFA++L K LG+ DNS+NVFFSPMS+S ALAMV+MGAKG+TAAQM+Q L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 60  NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
            K G   DIH+GFQSLL+EVN+TGTQYLLR ANRLFGEK+CDFL  F++ CQKFYQAE+E
Sbjct: 61  YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117

Query: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
           EL F    E+ RKHIN WVAEKTEGKI+E+L  G+VDPLT+LVLVNA+YF+G W+EQFD+
Sbjct: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177

Query: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 239
           + T   LFK ++ E+K VQMMFK++ FK  Y  E+ TQ+L LPYV +EL+M+I+LPD+ T
Sbjct: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236

Query: 240 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 299
           DL  VEK LTYEKF  WT  + + + +V+V LPR KLEESYD+E  LR LGM DAF+  K
Sbjct: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296

Query: 300 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF 358
           ADFSGMS + ++ LSKV HK FVEVNEEGTEAAAATA +   RC+R  PRFCADHPFLFF
Sbjct: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356

Query: 359 IQHSKTNGILFCGRFSSP 376
           I+H KTN ILFCGRFSSP
Sbjct: 357 IRHHKTNCILFCGRFSSP 374


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  474 bits (1220), Expect = e-134
 Identities = 238/379 (62%), Positives = 297/379 (78%), Gaps = 6/379 (1%)

Query: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           M+ L+ A+GTFA+ LLK L +DN S NVF SP+S+S ALAMV +GAKGNTA QMAQ LS 
Sbjct: 1   METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60

Query: 60  NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
           N      DIH+ FQSLLTEVNK GTQYLLR ANRLFGEK+C FLS+F++SC +FY AE++
Sbjct: 61  NTEE---DIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELK 117

Query: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
           EL FI A E+SRKHINTWV++KTEGKI ELL   S+D  TRLVLVNA+YF+G W+E FD+
Sbjct: 118 ELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDE 177

Query: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 239
             T E  FK+++ E++PVQMM++++TFK  ++GE+  Q+L LPY  KEL+++++LPD+  
Sbjct: 178 TYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGV 237

Query: 240 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 299
           +L TVEK LT+EK   WT+ D M   EVEV LP+FKL+E YDMESVLR+LG+ DAF+ GK
Sbjct: 238 ELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK 297

Query: 300 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCA-RFVPRFCADHPFLF 357
           AD S MS + DL LSK VHKSFVEVNEEGTEAAAA++  ++  C     PRFCADHPFLF
Sbjct: 298 ADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLF 357

Query: 358 FIQHSKTNGILFCGRFSSP 376
           FI+H++ N ILFCGRFSSP
Sbjct: 358 FIRHNRANSILFCGRFSSP 376


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  368 bits (944), Expect = e-102
 Identities = 195/382 (51%), Positives = 264/382 (69%), Gaps = 9/382 (2%)

Query: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           M+ L+ AN  FAL+L   L ++N + N+F SP S+S A+AMV++G +GNTAAQ+++   F
Sbjct: 1   MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60

Query: 60  NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
           N      ++H  FQSL  ++NK G  Y+L++ANRL+GEK+ +FL  F  S QK Y A++ 
Sbjct: 61  NTVE---EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLA 117

Query: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
            +DF  A E +RK IN WV  +TEGKI ELL+ G VD +T+LVLVNA+YF+GNW ++F K
Sbjct: 118 SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMK 177

Query: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLP---- 235
           E T    F+++K + K V+MM+++  F   YI ++  ++L LPY G+EL+M+I+LP    
Sbjct: 178 EATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIE 237

Query: 236 DETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAF 295
           DE+T L+ +E++LT EK  EWT+ + +D  EV VSLPRFKLEESY + S L  LG+ D F
Sbjct: 238 DESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLF 297

Query: 296 ELGKADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHP 354
              KAD SGMS   D+ +SK+VHKSFVEVNEEGTEAAAATA I           F ADHP
Sbjct: 298 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHP 357

Query: 355 FLFFIQHSKTNGILFCGRFSSP 376
           FLFFI+H+ +  ILF GRFSSP
Sbjct: 358 FLFFIRHNSSGSILFLGRFSSP 379


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  346 bits (888), Expect = 2e-95
 Identities = 182/391 (46%), Positives = 259/391 (66%), Gaps = 16/391 (4%)

Query: 1   MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN 60
           M+ L+EAN  F  +L +   K    N+F+SP+S++ AL MV +GAK NTA Q++++L F+
Sbjct: 1   MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFD 60

Query: 61  KS-------------GGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFR 107
           +                 G++H  FQ LLTE NK+   Y L++AN+LFGEK+  FL  + 
Sbjct: 61  QVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYL 120

Query: 108 DSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAV 167
           D+ +KFYQ  +E  DF +A E+SRK IN+WV  +T  KI  L   G++   T LVLVNA+
Sbjct: 121 DAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAI 180

Query: 168 YFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKE 227
           YF+G W+ +F KENT+E  F  +KN  K VQMM + ++F    + ++  ++L +PY GK+
Sbjct: 181 YFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKD 240

Query: 228 LNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLR 287
           L+MI++LP+E   L+ +E++LT EK +EWT L  M E  V++ LPRFK+EESYD++  LR
Sbjct: 241 LSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLR 300

Query: 288 NLGMTDAFELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMM-MRCARF 345
            +GM + F  G AD SGM+ +  LS+SKV+HK+FVEV EEG EAAAATA +++ +     
Sbjct: 301 TMGMVNIFN-GDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPST 359

Query: 346 VPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
              FC +HPFLFFI+ +KTN ILF GRFSSP
Sbjct: 360 NEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  343 bits (880), Expect = 1e-94
 Identities = 189/416 (45%), Positives = 256/416 (61%), Gaps = 41/416 (9%)

Query: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           M+ L  AN  FALNL K L K + ++N+F SP S+S  +AMVYMG++G+T  QMA++L F
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 60  NKSGGGG----------------------------------DIHQGFQSLLTEVNKTGTQ 85
           N+ G                                      IH  F+SL + +N +   
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145
           YLL   N+LFGEKS  F   +   CQK+Y +E + +DF+   E++RK IN+WV  +T+GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 146 IAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQST 205
           I  LL  GSVD  TR+VLVNAVYF+G W   F+K+      F+V+  +  PVQMM+ +  
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 206 FKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRT----VEKELTYEKFVEWTRLDM 261
               YI ++  QIL LPY G +++M ++LPDE  D+ T    +E E+TY+K  +WT  D 
Sbjct: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299

Query: 262 MDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ-TDLSLSKVVHKSF 320
           M E+EVEV +P+FKLEE Y++ S+LR++GM DAF  G+A+FSGMS+  DL LS+V H++ 
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359

Query: 321 VEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
           V+VNEEGTEAAA T  +M  R     P+F ADHPFLF I H  TN ILF GRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  343 bits (880), Expect = 1e-94
 Identities = 189/416 (45%), Positives = 256/416 (61%), Gaps = 41/416 (9%)

Query: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           M+ L  AN  FALNL K L K + ++N+F SP S+S  +AMVYMG++G+T  QMA++L F
Sbjct: 1   MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60

Query: 60  NKSGGGG----------------------------------DIHQGFQSLLTEVNKTGTQ 85
           N+ G                                      IH  F+SL + +N +   
Sbjct: 61  NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120

Query: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145
           YLL   N+LFGEKS  F   +   CQK+Y +E + +DF+   E++RK IN+WV  +T+GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180

Query: 146 IAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQST 205
           I  LL  GSVD  TR+VLVNAVYF+G W   F+K+      F+V+  +  PVQMM+ +  
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240

Query: 206 FKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRT----VEKELTYEKFVEWTRLDM 261
               YI ++  QIL LPY G +++M ++LPDE  D+ T    +E E+TY+K  +WT  D 
Sbjct: 241 LNIGYIEDLKAQILELPYAG-DVSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299

Query: 262 MDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ-TDLSLSKVVHKSF 320
           M E+EVEV +P+FKLEE Y++ S+LR++GM DAF  G+A+FSGMS+  DL LS+V H++ 
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359

Query: 321 VEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
           V+VNEEGTEAAA T  +M  R     P+F ADHPFLF I H  TN ILF GRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  337 bits (864), Expect = 1e-92
 Identities = 181/391 (46%), Positives = 256/391 (65%), Gaps = 16/391 (4%)

Query: 1   MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF- 59
           M+ L+EAN  F  +L +   K    N+F+SP+S++ AL MV +GAK NTA Q+ ++L F 
Sbjct: 1   MNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFD 60

Query: 60  ----NKSGGG--------GDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFR 107
               N +G          G++H  FQ LLTE NK+   Y L++AN+LFGEK+  FL  + 
Sbjct: 61  QVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYL 120

Query: 108 DSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAV 167
           D+ +KFYQ  +E +DF +A E+SRK IN+WV  +T  KI  L+  G++   T LVLVNA+
Sbjct: 121 DAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAI 180

Query: 168 YFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKE 227
           YF+G W+++F+KE+T+E  F  +KN  K +QMM + ++F    + ++  ++L +PY GK+
Sbjct: 181 YFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKD 240

Query: 228 LNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLR 287
           L+MI++LP+E   L+ +E++LT EK +EWT L  M E  V++ LPRFK+EESYD++  LR
Sbjct: 241 LSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLR 300

Query: 288 NLGMTDAFELGKADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFV 346
            +GM D F  G AD SGM+    L LS V+HK+FVEV EEG EAAAATA +         
Sbjct: 301 TMGMVDIFN-GDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTST 359

Query: 347 -PRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
              F  +HPFLFFI+ +KTN ILF GRFSSP
Sbjct: 360 NEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 10 [Homo sapiens]
          Length = 397

 Score =  334 bits (857), Expect = 7e-92
 Identities = 179/397 (45%), Positives = 256/397 (64%), Gaps = 21/397 (5%)

Query: 1   MDVLAEANGTFALNLLKTLGKD-NSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           MD LA +   FAL L K L +    KN+FFS  S+S +L +VY+GAKG TAAQMAQ+L F
Sbjct: 1   MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60

Query: 60  NKSGG-------------------GGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSC 100
           N+  G                     +IH  FQ+L++E+ K    YLL+ AN ++GEK+ 
Sbjct: 61  NRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTY 120

Query: 101 DFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTR 160
            F + + +  + ++ AE + ++F+ A ++ RK IN+WV  +TEGKI  LL   SVD  TR
Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180

Query: 161 LVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILV 220
           ++LVNA+YF+G W+ QF  +NT E+ F++++   KPVQMMF +      +I +     L 
Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240

Query: 221 LPYVGKELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESY 280
           L Y  ++L+++I+LP++   L  +EK +TYEK  EWT  DMM+  EV++ LP+FKLE+SY
Sbjct: 241 LYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSY 300

Query: 281 DMESVLRNLGMTDAFELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMM 339
           D++S L ++GM+DAF   KADFSGMS   +L LS V HK+FVE+NE+GTEAAA + + + 
Sbjct: 301 DLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEID 360

Query: 340 MRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
           +R       F A+HPFLFFI+H+KTN ILF GR  SP
Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397


>gi|73623033 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform b [Homo sapiens]
          Length = 242

 Score =  322 bits (825), Expect = 3e-88
 Identities = 162/246 (65%), Positives = 199/246 (80%), Gaps = 5/246 (2%)

Query: 1   MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           MD L EANGTFA++L K LG+ DNS+NVFFSPMS+S ALAMV+MGAKG+TAAQM+Q L  
Sbjct: 1   MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60

Query: 60  NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
            K G   DIH+GFQSLL+EVN+TGTQYLLR ANRLFGEK+CDFL  F++ CQKFYQAE+E
Sbjct: 61  YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117

Query: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
           EL F    E+ RKHIN WVAEKTEGKI+E+L  G+VDPLT+LVLVNA+YF+G W+EQFD+
Sbjct: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177

Query: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 239
           + T   LFK ++ E+K VQMMFK++ FK  Y  E+ TQ+L LPYV +EL+M+I+LPD+ T
Sbjct: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236

Query: 240 DLRTVE 245
           DL   E
Sbjct: 237 DLAVKE 242


>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 13 [Homo sapiens]
          Length = 391

 Score =  317 bits (812), Expect = 1e-86
 Identities = 167/391 (42%), Positives = 238/391 (60%), Gaps = 15/391 (3%)

Query: 1   MDVLAEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN 60
           MD L   +     +L K L K N  N+FFSP+ +  A+ MV +G +G TA+Q+ ++    
Sbjct: 1   MDSLGAVSTRLGFDLFKELKKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSE 60

Query: 61  KSGGGGDI--------------HQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSF 106
           K      I              HQ FQ  LTE++K    Y L + NRLFGEK+  FL  +
Sbjct: 61  KETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKY 120

Query: 107 RDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNA 166
            D  +K+Y A +E +DF++A ++SRK IN+WV  KT  KI +L   GS+   T+LVLVN 
Sbjct: 121 LDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNM 180

Query: 167 VYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGK 226
           VYF+G WD +F KENT+E  F ++K+  K VQMM +  +F  T++ ++  +IL +PY   
Sbjct: 181 VYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNN 240

Query: 227 ELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVL 286
           +L+M ++LP++   L  +  +++ EK VEWT    M+E +V + LPRF++E+ YD+E+VL
Sbjct: 241 DLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVL 300

Query: 287 RNLGMTDAFELGKADFSGMSQ-TDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARF 345
             +GM DAF   KAD+SGMS  + L   K +H SFV V EEGTEAAAAT     +  A  
Sbjct: 301 AAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAPG 360

Query: 346 VPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
                 +HPFLFFI+H+++N ILF GRFSSP
Sbjct: 361 HENVHCNHPFLFFIRHNESNSILFFGRFSSP 391


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  312 bits (799), Expect = 4e-85
 Identities = 166/392 (42%), Positives = 243/392 (61%), Gaps = 16/392 (4%)

Query: 1   MDVLAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           M  L+ AN  F L++ K L  +N   N+FFS +S+  AL+MV +GA+G T  Q+ ++L F
Sbjct: 1   MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60

Query: 60  N--------------KSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSS 105
           +              K    G IH  F    +++N+  +   L +ANRL+G K+  F   
Sbjct: 61  SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120

Query: 106 FRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVN 165
           +    +K+YQA ++ +DF  + E++RK IN WV  KT GK+A L    ++DP + +VLVN
Sbjct: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180

Query: 166 AVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVG 225
           A+YF+G W  +F    T +  F++S+ +   V+MM++  TFK  ++ E   Q+L LPYV 
Sbjct: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240

Query: 226 KELNMIIMLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESV 285
            +L+MII+LP    +L+ +EK+L    F EWT    M E EVEV LPRFKLE  Y++ S+
Sbjct: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300

Query: 286 LRNLGMTDAFELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCAR 344
           L++LG+TD F   KAD SGMS T  L LSK +HKS+++V+EEGTEAAAAT   + ++   
Sbjct: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360

Query: 345 FVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
              +F A+HPFLFFI+H+ TN ILFCG+ +SP
Sbjct: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 12 [Homo sapiens]
          Length = 405

 Score =  306 bits (784), Expect = 2e-83
 Identities = 169/405 (41%), Positives = 252/405 (62%), Gaps = 29/405 (7%)

Query: 1   MDVLAEANGTFALNLLKTLGKDNS-KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           MD L  AN  F  +L + +GKD+  KN+FFSP+S+S AL MV +GA+ ++A Q+ ++L F
Sbjct: 1   MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60

Query: 60  N-------------------KSGG----GGDIHQGFQSLLTEVNKTGTQYLLRMANRLFG 96
           N                   K+G      G +   F  LL+++++  T Y L +ANRL+G
Sbjct: 61  NEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 120

Query: 97  EKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVD 156
           E+       + D   +FY   +E +DF    EKSR+ IN WV  +++GKI EL S  +++
Sbjct: 121 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAIN 180

Query: 157 PLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFT 216
             T LVLVNAVYF+  W+  FD ENT +  F ++ NE K V+MM ++  ++  +I E+  
Sbjct: 181 AETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 240

Query: 217 QILVLPYVGKELNMIIMLPDETTD----LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLP 272
           QIL + Y   +L+M ++LP  + D    L  +E+++TYEK V W+  + M EE V +S P
Sbjct: 241 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFP 300

Query: 273 RFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAA 331
           RF LE+SYD+ S+L+++G+TD F+  +AD +G+S + +L LSK++HK+FVEV+E GT+AA
Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360

Query: 332 AATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
           AAT A++  R  R    F A+HPFLFFI+H+KT  ILF GR  SP
Sbjct: 361 AATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405


>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 5 [Homo sapiens]
          Length = 375

 Score =  259 bits (663), Expect = 2e-69
 Identities = 143/382 (37%), Positives = 231/382 (60%), Gaps = 13/382 (3%)

Query: 1   MDVLAEANGTFALNLLKTL-GKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           MD L  AN  FA++L K L  K+   NV FSP+ +S +L++  +GAKG+TA ++ Q+L F
Sbjct: 1   MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60

Query: 60  NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
                  D+  GFQ++ ++VNK  + Y L++  RL+ +KS +  + F  S ++ Y  E+E
Sbjct: 61  ENVK---DVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELE 117

Query: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
            +DF   +E+++  IN  + + T+G    +L+  SV+  T++++VNA YF G W ++F +
Sbjct: 118 TVDFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSE 177

Query: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLP---- 235
             T+E  F+V+K + KPVQMM  ++TF    I  I  +I+ LP+  K L+M I+LP    
Sbjct: 178 SETKECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVE 237

Query: 236 DETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAF 295
           DE+T L  +EK+L  E   +WT    M   +V++S+P+FK+E+  D ++ L NLG+   F
Sbjct: 238 DESTGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIF 297

Query: 296 ELGKADFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHP 354
               +DFSGMS+T  ++LS V+HK  +E+ E+G ++     A    R  +      ADHP
Sbjct: 298 SEDTSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGA----RILQHKDELNADHP 353

Query: 355 FLFFIQHSKTNGILFCGRFSSP 376
           F++ I+H+KT  I+F G+F SP
Sbjct: 354 FIYIIRHNKTRNIIFFGKFCSP 375


>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  246 bits (628), Expect = 2e-65
 Identities = 148/385 (38%), Positives = 223/385 (57%), Gaps = 14/385 (3%)

Query: 1   MDVLAEANGTFALNLLKTLGKDNSK-NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           M  LA AN  F  NL + +  +    NVFFS +S+  ALA+V +GA+ ++ +Q+ ++L  
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 60  NKSGGGGDI---HQGFQSLL----TEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQK 112
           N + G G+      G QS L    +++N +   Y L + N LF EK   F   + +  +K
Sbjct: 61  NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120

Query: 113 FYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGN 172
            Y A++E +DF + +E +R++IN WV  +T GKI  ++  G +     +VLVNAVYF+G 
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180

Query: 173 WDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMII 232
           W   F K  T    FK  K   K V MM ++  F  + I +   +IL L Y G  +NM +
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRYNG-GINMYV 239

Query: 233 MLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMT 292
           +LP+   DL  +E +LT++  +EWT    M  + VEV  P+FK+E++Y+M+  LR LG+ 
Sbjct: 240 LLPE--NDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297

Query: 293 DAFELGKADFSGM-SQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCA 351
           D F+  KAD SG+ S   L +S+++HKS++EV EEGTEA AAT + ++ +       F A
Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357

Query: 352 DHPFLFFIQHSKTNGILFCGRFSSP 376
           DHPFLF I+  K + ILF G+ S P
Sbjct: 358 DHPFLFVIR--KDDIILFSGKVSCP 380


>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 7 [Homo sapiens]
          Length = 380

 Score =  246 bits (628), Expect = 2e-65
 Identities = 148/385 (38%), Positives = 223/385 (57%), Gaps = 14/385 (3%)

Query: 1   MDVLAEANGTFALNLLKTLGKDNSK-NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
           M  LA AN  F  NL + +  +    NVFFS +S+  ALA+V +GA+ ++ +Q+ ++L  
Sbjct: 1   MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60

Query: 60  NKSGGGGDI---HQGFQSLL----TEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQK 112
           N + G G+      G QS L    +++N +   Y L + N LF EK   F   + +  +K
Sbjct: 61  NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120

Query: 113 FYQAEMEELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGN 172
            Y A++E +DF + +E +R++IN WV  +T GKI  ++  G +     +VLVNAVYF+G 
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180

Query: 173 WDEQFDKENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMII 232
           W   F K  T    FK  K   K V MM ++  F  + I +   +IL L Y G  +NM +
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRYNG-GINMYV 239

Query: 233 MLPDETTDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMT 292
           +LP+   DL  +E +LT++  +EWT    M  + VEV  P+FK+E++Y+M+  LR LG+ 
Sbjct: 240 LLPE--NDLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297

Query: 293 DAFELGKADFSGM-SQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCA 351
           D F+  KAD SG+ S   L +S+++HKS++EV EEGTEA AAT + ++ +       F A
Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357

Query: 352 DHPFLFFIQHSKTNGILFCGRFSSP 376
           DHPFLF I+  K + ILF G+ S P
Sbjct: 358 DHPFLFVIR--KDDIILFSGKVSCP 380


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  241 bits (616), Expect = 6e-64
 Identities = 142/384 (36%), Positives = 221/384 (57%), Gaps = 16/384 (4%)

Query: 4   LAEANGTFALNLLKTLG--KDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN- 60
           L++AN  FA    + L   K+++ N+F SP+S+S A AM  +GA  +T  Q+ ++  F+ 
Sbjct: 83  LSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDT 142

Query: 61  -KSGGGGDIHQGFQSLLTEV-NKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEM 118
                   IH  F  L   +  K      L  ANRLFG+KS  F  +++D  +  Y A++
Sbjct: 143 ISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKL 202

Query: 119 EELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFD 178
           + LDF    E+SR  IN WV+ KTEG+I +++   +++ LT LVLVN +YF+G W  +F 
Sbjct: 203 QPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFS 262

Query: 179 KENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDET 238
            ENT + LF  +  E     MM+++  F+   + E  TQ+L LP+ G ++ M+++LP   
Sbjct: 263 PENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPE 321

Query: 239 TDLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELG 298
             L  VEKELT E   EW  LD ++E  + V +PRF++E+ + ++  L+++G+ D F   
Sbjct: 322 KSLAKVEKELTPEVLQEW--LDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPE 379

Query: 299 KADFSGM---SQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPR---FCAD 352
           K+   G+    + DL +S   HK+F+EVNEEG+EAAA+TA ++  R     P    F A+
Sbjct: 380 KSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLN--PNRVTFKAN 437

Query: 353 HPFLFFIQHSKTNGILFCGRFSSP 376
            PFL FI+    N I+F GR ++P
Sbjct: 438 RPFLVFIREVPLNTIIFMGRVANP 461


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  229 bits (585), Expect = 2e-60
 Identities = 131/375 (34%), Positives = 218/375 (58%), Gaps = 8/375 (2%)

Query: 5   AEANGTFALNLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGG 64
           A+ N  FA++L + +   +  N+ FSP+ ++  L MV +GAKG    Q+ Q L   ++  
Sbjct: 23  AQKNTEFAVDLYQEVSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSA 82

Query: 65  GGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFI 124
           G +     +S  + +++   ++   +AN L+ ++       +    ++F+Q+ ++ +DF 
Sbjct: 83  GEEFFV-LKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQ 141

Query: 125 SAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEE 184
            A +   + I+TWV  KT+GKI ++ S     PLTRLVLVNA+YF+G+W ++F KE+T+ 
Sbjct: 142 DA-KACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQL 200

Query: 185 RLFKVSKNEEKPVQMMFKQSTFKKTYIGE--IFTQILVLPYVGKELNMIIMLPDETTDLR 242
             F         + MM      K  Y  E  +  Q+L L Y G E ++II+LP E  D+ 
Sbjct: 201 INFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIE 260

Query: 243 TVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADF 302
            VEK +T ++ ++W  L  M EEEVE+SLPRFK+E+  D + VL +L +T+ F  G  D 
Sbjct: 261 EVEKLITAQQILKW--LSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFS-GGCDL 317

Query: 303 SGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQH 361
           SG++  +++ +S+V  K F E+NE+G+EAA +T   + +  +    +F A+HPFLF ++H
Sbjct: 318 SGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKH 377

Query: 362 SKTNGILFCGRFSSP 376
           + T  ILF GR ++P
Sbjct: 378 NPTESILFMGRVTNP 392


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  223 bits (569), Expect = 2e-58
 Identities = 134/377 (35%), Positives = 217/377 (57%), Gaps = 28/377 (7%)

Query: 14  NLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN--KSGGGGDIHQG 71
           N L+  G+D  +N+ FSP+S++ A+ M+ +GA+G+T  ++   + ++  K+G      + 
Sbjct: 35  NRLRATGED--ENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKE 92

Query: 72  FQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSR 131
           F +++T      +QY++++AN LF +        F    +K++ A +  +DF   V  + 
Sbjct: 93  FSNMVTAKE---SQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVAN 149

Query: 132 KHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSK 191
            +IN WV   T   + +L+SP   D  T L L+NAVYF+GNW  QF  ENT  R F  +K
Sbjct: 150 -YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENT--RTFSFTK 206

Query: 192 NEEKPVQ--MMFKQSTFKKTYIGEI---------FTQILVLPYVGKELNMIIMLPDETTD 240
           ++E  VQ  MM++Q  F   Y GE            Q+L +PY G E++M+++L  +   
Sbjct: 207 DDESEVQIPMMYQQGEF---YYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263

Query: 241 LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKA 300
           L T+E  +  +   EW   + + +++VEV LPRF +E+  D++ VL+ LG+T+ F +  A
Sbjct: 264 LATLEPLVKAQLVEEWA--NSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKDA 320

Query: 301 DFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFI 359
           + +G+S   ++ LSK +HKSF+EVNEEG+EAAA +  I + R A   P+   DHPF F I
Sbjct: 321 NLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLI 380

Query: 360 QHSKTNGILFCGRFSSP 376
           ++ +T  ILF GR   P
Sbjct: 381 RNRRTGTILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  223 bits (569), Expect = 2e-58
 Identities = 134/377 (35%), Positives = 217/377 (57%), Gaps = 28/377 (7%)

Query: 14  NLLKTLGKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN--KSGGGGDIHQG 71
           N L+  G+D  +N+ FSP+S++ A+ M+ +GA+G+T  ++   + ++  K+G      + 
Sbjct: 35  NRLRATGED--ENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEEFSFLKE 92

Query: 72  FQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSR 131
           F +++T      +QY++++AN LF +        F    +K++ A +  +DF   V  + 
Sbjct: 93  FSNMVTAKE---SQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVAN 149

Query: 132 KHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSK 191
            +IN WV   T   + +L+SP   D  T L L+NAVYF+GNW  QF  ENT  R F  +K
Sbjct: 150 -YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENT--RTFSFTK 206

Query: 192 NEEKPVQ--MMFKQSTFKKTYIGEI---------FTQILVLPYVGKELNMIIMLPDETTD 240
           ++E  VQ  MM++Q  F   Y GE            Q+L +PY G E++M+++L  +   
Sbjct: 207 DDESEVQIPMMYQQGEF---YYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVP 263

Query: 241 LRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKA 300
           L T+E  +  +   EW   + + +++VEV LPRF +E+  D++ VL+ LG+T+ F +  A
Sbjct: 264 LATLEPLVKAQLVEEWA--NSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIF-IKDA 320

Query: 301 DFSGMSQT-DLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFI 359
           + +G+S   ++ LSK +HKSF+EVNEEG+EAAA +  I + R A   P+   DHPF F I
Sbjct: 321 NLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLI 380

Query: 360 QHSKTNGILFCGRFSSP 376
           ++ +T  ILF GR   P
Sbjct: 381 RNRRTGTILFMGRVMHP 397


>gi|211904156 plasminogen activator inhibitor type 1, member 2
           isoform c precursor [Homo sapiens]
          Length = 409

 Score =  191 bits (486), Expect = 7e-49
 Identities = 115/357 (32%), Positives = 204/357 (57%), Gaps = 15/357 (4%)

Query: 26  NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQ 85
           N+  SP  ++  L M+ +GA G T  Q+A ++ +  +G G  + +  ++++++ NK    
Sbjct: 62  NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKD--- 118

Query: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145
            ++ +AN +F + + +    F    +  +Q E+  ++F          IN WV  +T   
Sbjct: 119 -IVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKNETRDM 176

Query: 146 IAELLSPGSVDP-LTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 204
           I  LLSP  +D  LTRLVLVNAVYF+G W  +F  ENT++R F  +  +   V M+ + S
Sbjct: 177 IDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLS 236

Query: 205 TFK---KTYIGEIFTQILVLPYVGKELNMIIMLPDE-TTDLRTVEKELTYEKFVEWTRLD 260
            F+    +   +++   + LPY G+ ++M+I LP E +T L  +   ++ +    W  + 
Sbjct: 237 VFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSW--MS 294

Query: 261 MMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTD-LSLSKVVHKS 319
           +M  + V+V LP+F      D++  L+ LG+TD F+  KA+F+ +++++ L +S ++ K+
Sbjct: 295 IMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKA 354

Query: 320 FVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
            +EV+E+GT+A+AAT AI++ R +   P F  D PFLFFI+H+ T  +LF G+ + P
Sbjct: 355 KIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 409


>gi|211904154 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  191 bits (486), Expect = 7e-49
 Identities = 115/357 (32%), Positives = 204/357 (57%), Gaps = 15/357 (4%)

Query: 26  NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQ 85
           N+  SP  ++  L M+ +GA G T  Q+A ++ +  +G G  + +  ++++++ NK    
Sbjct: 50  NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKD--- 106

Query: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145
            ++ +AN +F + + +    F    +  +Q E+  ++F          IN WV  +T   
Sbjct: 107 -IVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKNETRDM 164

Query: 146 IAELLSPGSVDP-LTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 204
           I  LLSP  +D  LTRLVLVNAVYF+G W  +F  ENT++R F  +  +   V M+ + S
Sbjct: 165 IDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLS 224

Query: 205 TFK---KTYIGEIFTQILVLPYVGKELNMIIMLPDE-TTDLRTVEKELTYEKFVEWTRLD 260
            F+    +   +++   + LPY G+ ++M+I LP E +T L  +   ++ +    W  + 
Sbjct: 225 VFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSW--MS 282

Query: 261 MMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTD-LSLSKVVHKS 319
           +M  + V+V LP+F      D++  L+ LG+TD F+  KA+F+ +++++ L +S ++ K+
Sbjct: 283 IMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKA 342

Query: 320 FVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
            +EV+E+GT+A+AAT AI++ R +   P F  D PFLFFI+H+ T  +LF G+ + P
Sbjct: 343 KIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|211904152 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  191 bits (486), Expect = 7e-49
 Identities = 115/357 (32%), Positives = 204/357 (57%), Gaps = 15/357 (4%)

Query: 26  NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQ 85
           N+  SP  ++  L M+ +GA G T  Q+A ++ +  +G G  + +  ++++++ NK    
Sbjct: 50  NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKD--- 106

Query: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145
            ++ +AN +F + + +    F    +  +Q E+  ++F          IN WV  +T   
Sbjct: 107 -IVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKNETRDM 164

Query: 146 IAELLSPGSVDP-LTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 204
           I  LLSP  +D  LTRLVLVNAVYF+G W  +F  ENT++R F  +  +   V M+ + S
Sbjct: 165 IDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLS 224

Query: 205 TFK---KTYIGEIFTQILVLPYVGKELNMIIMLPDE-TTDLRTVEKELTYEKFVEWTRLD 260
            F+    +   +++   + LPY G+ ++M+I LP E +T L  +   ++ +    W  + 
Sbjct: 225 VFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSW--MS 282

Query: 261 MMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQTD-LSLSKVVHKS 319
           +M  + V+V LP+F      D++  L+ LG+TD F+  KA+F+ +++++ L +S ++ K+
Sbjct: 283 IMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKA 342

Query: 320 FVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
            +EV+E+GT+A+AAT AI++ R +   P F  D PFLFFI+H+ T  +LF G+ + P
Sbjct: 343 KIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 397


>gi|24307907 plasminogen activator inhibitor type 1, member 2
           isoform a precursor [Homo sapiens]
          Length = 398

 Score =  189 bits (481), Expect = 3e-48
 Identities = 115/358 (32%), Positives = 202/358 (56%), Gaps = 16/358 (4%)

Query: 26  NVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGTQ 85
           N+  SP  ++  L M+ +GA G T  Q+A ++ +  +G G  + +  ++++++ NK    
Sbjct: 50  NIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKD--- 106

Query: 86  YLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEGK 145
            ++ +AN +F + + +    F    +  +Q E+  ++F          IN WV  +T   
Sbjct: 107 -IVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDS-INAWVKNETRDM 164

Query: 146 IAELLSPGSVDP-LTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 204
           I  LLSP  +D  LTRLVLVNAVYF+G W  +F  ENT++R F  +  +   V M+ + S
Sbjct: 165 IDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLS 224

Query: 205 TFK---KTYIGEIFTQILVLPYVGKELNMIIMLPDE-TTDLRTVEKELTYEKFVEWTRLD 260
            F+    +   +++   + LPY G+ ++M+I LP E +T L  +   ++ +    W  + 
Sbjct: 225 VFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSW--MS 282

Query: 261 MMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS--QTDLSLSKVVHK 318
           +M  + V+V LP+F      D++  L+ LG+TD F+  KA+F+ ++    +L +S ++ K
Sbjct: 283 IMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITTGSENLHVSHILQK 342

Query: 319 SFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSSP 376
           + +EV+E+GT+A+AAT AI++ R +   P F  D PFLFFI+H+ T  +LF G+ + P
Sbjct: 343 AKIEVSEDGTKASAATTAILIARSS--PPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 398


>gi|73858564 corticosteroid binding globulin precursor [Homo
           sapiens]
          Length = 405

 Score =  187 bits (475), Expect = 1e-47
 Identities = 129/376 (34%), Positives = 201/376 (53%), Gaps = 13/376 (3%)

Query: 4   LAEANGTFALNLLKTL-GKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKS 62
           LA AN  FA +L K L      KN+F SP+S+S ALAM+ +G  G+T AQ+ Q L FN +
Sbjct: 39  LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98

Query: 63  GGGG-DIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEEL 121
                +IHQGFQ L     K+ T   + M N LF + S + L SF    + +Y++E+  +
Sbjct: 99  ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158

Query: 122 DFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKEN 181
           +F      SR+ IN++V  KT+GKI +L S   +D    LVLVN ++F+G W + FD  +
Sbjct: 159 NFQDWATASRQ-INSYVKNKTQGKIVDLFS--GLDSPAILVLVNYIFFKGTWTQPFDLAS 215

Query: 182 TEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDL 241
           T E  F V +     V MM + ST    +  E+  Q++ + YVG    +  +LPD+   +
Sbjct: 216 TREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG-TVFFILPDK-GKM 273

Query: 242 RTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKAD 301
            TV   L+ +    W+    +   +V++ +P+  +   YD+  VL  +G+ D F   +A+
Sbjct: 274 NTVIAALSRDTINRWSA--GLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLF-TNQAN 330

Query: 302 FSGMSQ-TDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQ 360
           FS ++Q   L  SKVVHK+ +++NEEG + A +T   + +     + RF  + PF+  I 
Sbjct: 331 FSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRF--NQPFIIMIF 388

Query: 361 HSKTNGILFCGRFSSP 376
              T   LF  R  +P
Sbjct: 389 DHFTWSSLFLARVMNP 404


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  184 bits (468), Expect = 9e-47
 Identities = 124/371 (33%), Positives = 203/371 (54%), Gaps = 17/371 (4%)

Query: 11  FALNLLKTLG-KDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSG-GGGDI 68
           FA +L + L  + NS N+FFSP+S++ A AM+ +G K +T  ++ + L+FN +      I
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116

Query: 69  HQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVE 128
           H+GFQ LL  +N+  +Q  L   N LF  +    +  F +  +K Y +E   ++F    E
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNF-GDTE 175

Query: 129 KSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFK 188
           +++K IN +V + T+GKI +L+    +D  T   LVN ++F+G W+  F+ ++TEE  F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 189 VSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKEL 248
           V +     V MM +   F   +  ++ + +L++ Y+G     I  LPDE   L+ +E EL
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQHLENEL 291

Query: 249 TYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ- 307
           T++   ++  L+  D     + LP+  +  +YD++SVL  LG+T  F  G AD SG+++ 
Sbjct: 292 THDIITKF--LENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348

Query: 308 TDLSLSKVVHKSFVEVNEEGTEAAAA--TAAIMMMRCARFVPRFCADHPFLFFIQHSKTN 365
             L LSK VHK+ + ++E+GTEAA A    AI M       P    + PF+F +    T 
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPM----SIPPEVKFNKPFVFLMIEQNTK 404

Query: 366 GILFCGRFSSP 376
             LF G+  +P
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  184 bits (468), Expect = 9e-47
 Identities = 124/371 (33%), Positives = 203/371 (54%), Gaps = 17/371 (4%)

Query: 11  FALNLLKTLG-KDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSG-GGGDI 68
           FA +L + L  + NS N+FFSP+S++ A AM+ +G K +T  ++ + L+FN +      I
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116

Query: 69  HQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVE 128
           H+GFQ LL  +N+  +Q  L   N LF  +    +  F +  +K Y +E   ++F    E
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNF-GDTE 175

Query: 129 KSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFK 188
           +++K IN +V + T+GKI +L+    +D  T   LVN ++F+G W+  F+ ++TEE  F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 189 VSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKEL 248
           V +     V MM +   F   +  ++ + +L++ Y+G     I  LPDE   L+ +E EL
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQHLENEL 291

Query: 249 TYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ- 307
           T++   ++  L+  D     + LP+  +  +YD++SVL  LG+T  F  G AD SG+++ 
Sbjct: 292 THDIITKF--LENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348

Query: 308 TDLSLSKVVHKSFVEVNEEGTEAAAA--TAAIMMMRCARFVPRFCADHPFLFFIQHSKTN 365
             L LSK VHK+ + ++E+GTEAA A    AI M       P    + PF+F +    T 
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPM----SIPPEVKFNKPFVFLMIEQNTK 404

Query: 366 GILFCGRFSSP 376
             LF G+  +P
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  184 bits (468), Expect = 9e-47
 Identities = 124/371 (33%), Positives = 203/371 (54%), Gaps = 17/371 (4%)

Query: 11  FALNLLKTLG-KDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSG-GGGDI 68
           FA +L + L  + NS N+FFSP+S++ A AM+ +G K +T  ++ + L+FN +      I
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116

Query: 69  HQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVE 128
           H+GFQ LL  +N+  +Q  L   N LF  +    +  F +  +K Y +E   ++F    E
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNF-GDTE 175

Query: 129 KSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFK 188
           +++K IN +V + T+GKI +L+    +D  T   LVN ++F+G W+  F+ ++TEE  F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 189 VSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKEL 248
           V +     V MM +   F   +  ++ + +L++ Y+G     I  LPDE   L+ +E EL
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQHLENEL 291

Query: 249 TYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ- 307
           T++   ++  L+  D     + LP+  +  +YD++SVL  LG+T  F  G AD SG+++ 
Sbjct: 292 THDIITKF--LENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348

Query: 308 TDLSLSKVVHKSFVEVNEEGTEAAAA--TAAIMMMRCARFVPRFCADHPFLFFIQHSKTN 365
             L LSK VHK+ + ++E+GTEAA A    AI M       P    + PF+F +    T 
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPM----SIPPEVKFNKPFVFLMIEQNTK 404

Query: 366 GILFCGRFSSP 376
             LF G+  +P
Sbjct: 405 SPLFMGKVVNP 415


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  184 bits (468), Expect = 9e-47
 Identities = 124/371 (33%), Positives = 203/371 (54%), Gaps = 17/371 (4%)

Query: 11  FALNLLKTLG-KDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSG-GGGDI 68
           FA +L + L  + NS N+FFSP+S++ A AM+ +G K +T  ++ + L+FN +      I
Sbjct: 57  FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116

Query: 69  HQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVE 128
           H+GFQ LL  +N+  +Q  L   N LF  +    +  F +  +K Y +E   ++F    E
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNF-GDTE 175

Query: 129 KSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFK 188
           +++K IN +V + T+GKI +L+    +D  T   LVN ++F+G W+  F+ ++TEE  F 
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233

Query: 189 VSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLRTVEKEL 248
           V +     V MM +   F   +  ++ + +L++ Y+G     I  LPDE   L+ +E EL
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNA-TAIFFLPDEGK-LQHLENEL 291

Query: 249 TYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMSQ- 307
           T++   ++  L+  D     + LP+  +  +YD++SVL  LG+T  F  G AD SG+++ 
Sbjct: 292 THDIITKF--LENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348

Query: 308 TDLSLSKVVHKSFVEVNEEGTEAAAA--TAAIMMMRCARFVPRFCADHPFLFFIQHSKTN 365
             L LSK VHK+ + ++E+GTEAA A    AI M       P    + PF+F +    T 
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPM----SIPPEVKFNKPFVFLMIEQNTK 404

Query: 366 GILFCGRFSSP 376
             LF G+  +P
Sbjct: 405 SPLFMGKVVNP 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,442,461
Number of Sequences: 37866
Number of extensions: 496605
Number of successful extensions: 1405
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1111
Number of HSP's gapped (non-prelim): 79
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.