Guide to the Human Genome
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Search of human proteins with 40805827

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40805827 epsilon subunit of coatomer protein complex isoform
c [Homo sapiens]
         (256 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40805827 epsilon subunit of coatomer protein complex isoform ...   505   e-143
gi|31542319 epsilon subunit of coatomer protein complex isoform ...   481   e-136
gi|40805825 epsilon subunit of coatomer protein complex isoform ...   335   2e-92
gi|27262622 neuron navigator 1 [Homo sapiens]                          30   2.7  
gi|34577114 cytomatrix protein p110 [Homo sapiens]                     29   4.6  
gi|38198663 potassium channel tetramerisation domain containing ...    28   6.0  

>gi|40805827 epsilon subunit of coatomer protein complex isoform c
           [Homo sapiens]
          Length = 256

 Score =  505 bits (1300), Expect = e-143
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120

Query: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180
           LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
Sbjct: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180

Query: 181 LTQLATAWVSLATDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQA 240
           LTQLATAWVSLATDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQA
Sbjct: 181 LTQLATAWVSLATDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQA 240

Query: 241 KENDFDRLVLQYAPSA 256
           KENDFDRLVLQYAPSA
Sbjct: 241 KENDFDRLVLQYAPSA 256


>gi|31542319 epsilon subunit of coatomer protein complex isoform a
           [Homo sapiens]
          Length = 308

 Score =  481 bits (1237), Expect = e-136
 Identities = 256/308 (83%), Positives = 256/308 (83%), Gaps = 52/308 (16%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120

Query: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180
           LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT
Sbjct: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180

Query: 181 LTQLATAWVSLAT----------------------------------------------- 193
           LTQLATAWVSLAT                                               
Sbjct: 181 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 240

Query: 194 -----DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 248
                DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
Sbjct: 241 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 300

Query: 249 VLQYAPSA 256
           VLQYAPSA
Sbjct: 301 VLQYAPSA 308


>gi|40805825 epsilon subunit of coatomer protein complex isoform b
           [Homo sapiens]
          Length = 257

 Score =  335 bits (860), Expect = 2e-92
 Identities = 192/308 (62%), Positives = 198/308 (64%), Gaps = 103/308 (33%)

Query: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60
           MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY
Sbjct: 1   MAPPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAY 60

Query: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRRDSIVAELDREMSRSVDVTNTTFL 120
           LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESR  ++  ++  ++ R          
Sbjct: 61  LAQRKFGVVLDEIKPSSAPELQAVRMFADYLAHESRSTAMTVQILLKLDR---------- 110

Query: 121 LMAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDAT 180
                                                    LDLARKELKRMQDLDEDAT
Sbjct: 111 -----------------------------------------LDLARKELKRMQDLDEDAT 129

Query: 181 LTQLATAWVSLAT----------------------------------------------- 193
           LTQLATAWVSLAT                                               
Sbjct: 130 LTQLATAWVSLATGGEKLQDAYYIFQEMADKCSPTLLLLNGQAACHMAQGRWEAAEGLLQ 189

Query: 194 -----DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 248
                DSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL
Sbjct: 190 EALDKDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAKENDFDRL 249

Query: 249 VLQYAPSA 256
           VLQYAPSA
Sbjct: 250 VLQYAPSA 257


>gi|27262622 neuron navigator 1 [Homo sapiens]
          Length = 1874

 Score = 29.6 bits (65), Expect = 2.7
 Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 11/135 (8%)

Query: 122  MAASIYLHDQNPDAALRALHQGDSLECTAMTVQILLKLDRLDLARKELKRMQDLDEDATL 181
            M  S    D   D     L    S   T  + +  ++ +++   R+EL+  Q+  + ATL
Sbjct: 1043 MIRSGSFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQE--KVATL 1100

Query: 182  TQLATAWVSLATDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKEYQAK 241
            T   +A  +L   + + ++LVN+    +HL +  E  +   ++L D   +  F+K    K
Sbjct: 1101 TSQLSANANLV--AAFEQSLVNMTSRLRHLAETAEEKD---TELLDLRETIDFLK----K 1151

Query: 242  ENDFDRLVLQYAPSA 256
            +N   + V+Q A +A
Sbjct: 1152 KNSEAQAVIQGALNA 1166


>gi|34577114 cytomatrix protein p110 [Homo sapiens]
          Length = 957

 Score = 28.9 bits (63), Expect = 4.6
 Identities = 52/246 (21%), Positives = 99/246 (40%), Gaps = 20/246 (8%)

Query: 16  VDELFDVKNAFYIGSYQQCINEAQRVKLSSP--ERDVERDVFLYRAYLAQRKF-GVVLDE 72
           V E+ D K A    + +   +E Q +K +      D E ++     Y +  KF    +D+
Sbjct: 379 VIEMKDTKIASLERNIRDLEDEIQMLKANGVLNTEDREEEIKQIEVYKSHSKFMKTKIDQ 438

Query: 73  IKPSSAP---ELQAVRMFADYLAHESR---------RDSIVAELDREMSRSVDVTNTTFL 120
           +K   +    EL A++   + L++++          ++S+ A+  R      +V      
Sbjct: 439 LKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLR 498

Query: 121 LMAASIYLHDQNPDAALRALHQGDSL-ECTAMTVQILLKLDRLDLARKELKRMQDL--DE 177
           L     +L+ +          +G    E   M   + +K  ++++ +K+++ +Q+   D+
Sbjct: 499 LEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDK 558

Query: 178 DATLTQLATAWVSLATDSGYPETLVNLIVLSQHLGKPPEVTNRYLSQLKDAHRSHPFIKE 237
           D  LT L     SL TDS   +T   L  L + L +   +  R   Q +   R      E
Sbjct: 559 DKQLTNLKDRVKSLQTDSSNTDTA--LATLEEALSEKERIIERLKEQRERDDRERLEEIE 616

Query: 238 YQAKEN 243
              KEN
Sbjct: 617 SFRKEN 622


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 28.5 bits (62), Expect = 6.0
 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 3/99 (3%)

Query: 3   PPAPGPASGGSGEVDELFDVKNAFYIGSYQQCINEAQRVKLSSPERDVERDVFLYRAYLA 62
           P  PG   GG G   +  D ++ F    Y+      +  +  +  R V R +   R  LA
Sbjct: 187 PSGPGAHGGGGGGGAQ--DKRSGFLTLGYRGSYTTVRDNQADAKFRRVARIMVCGRIALA 244

Query: 63  QRKFGVVLDEIK-PSSAPELQAVRMFADYLAHESRRDSI 100
           +  FG  L+E + P   PE    R +  +   E   D +
Sbjct: 245 KEVFGDTLNESRDPDRQPEKYTSRFYLKFTYLEQAFDRL 283


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,711,885
Number of Sequences: 37866
Number of extensions: 388266
Number of successful extensions: 1173
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1167
Number of HSP's gapped (non-prelim): 7
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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