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Search of human proteins with 124256482
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo
sapiens]
(752 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens] 1562 0.0
gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens] 1543 0.0
gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens] 1475 0.0
gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens] 929 0.0
gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens] 891 0.0
gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 724 0.0
gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 724 0.0
gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 724 0.0
gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 724 0.0
gi|4758156 diacylglycerol kinase, iota [Homo sapiens] 270 3e-72
gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens] 270 5e-72
gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens] 270 5e-72
gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens] 270 5e-72
gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens] 270 5e-72
gi|40806175 diacylglycerol kinase, theta [Homo sapiens] 251 2e-66
gi|4503313 diacylglycerol kinase epsilon [Homo sapiens] 242 1e-63
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] 169 1e-41
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 169 1e-41
gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo ... 167 3e-41
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ... 167 3e-41
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 132 1e-30
gi|28557781 protein kinase C, eta [Homo sapiens] 53 9e-07
gi|13384594 protein kinase C, gamma [Homo sapiens] 53 1e-06
gi|5453976 protein kinase C, theta [Homo sapiens] 52 2e-06
gi|4885563 protein kinase C, epsilon [Homo sapiens] 52 2e-06
gi|163644313 calcium and integrin binding 1 [Homo sapiens] 52 2e-06
gi|98985795 neurocalcin delta [Homo sapiens] 52 3e-06
gi|98985793 neurocalcin delta [Homo sapiens] 52 3e-06
gi|98985791 neurocalcin delta [Homo sapiens] 52 3e-06
gi|98985789 neurocalcin delta [Homo sapiens] 52 3e-06
>gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens]
Length = 752
Score = 1562 bits (4044), Expect = 0.0
Identities = 752/752 (100%), Positives = 752/752 (100%)
Query: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR
Sbjct: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
Query: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC 120
AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC
Sbjct: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC 120
Query: 121 APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL 180
APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL
Sbjct: 121 APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL 180
Query: 181 EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV 240
EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV
Sbjct: 181 EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV 240
Query: 241 SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL 300
SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL
Sbjct: 241 SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL 300
Query: 301 CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGEFHRKCELSTLCDGGELRDHILLPTSIC 360
CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGEFHRKCELSTLCDGGELRDHILLPTSIC
Sbjct: 301 CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGEFHRKCELSTLCDGGELRDHILLPTSIC 360
Query: 361 PITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLL 420
PITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLL
Sbjct: 361 PITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLL 420
Query: 421 NPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPL 480
NPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPL
Sbjct: 421 NPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPL 480
Query: 481 GTGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIM 540
GTGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIM
Sbjct: 481 GTGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIM 540
Query: 541 NNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELE 600
NNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELE
Sbjct: 541 NNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELE 600
Query: 601 CDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQD 660
CDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQD
Sbjct: 601 CDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQD 660
Query: 661 LSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCT 720
LSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCT
Sbjct: 661 LSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCT 720
Query: 721 IKITHKNQAPMMMGPPQKSSFFSLRRKSRSKD 752
IKITHKNQAPMMMGPPQKSSFFSLRRKSRSKD
Sbjct: 721 IKITHKNQAPMMMGPPQKSSFFSLRRKSRSKD 752
>gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens]
Length = 791
Score = 1543 bits (3994), Expect = 0.0
Identities = 752/791 (95%), Positives = 752/791 (95%), Gaps = 39/791 (4%)
Query: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR
Sbjct: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
Query: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC 120
AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC
Sbjct: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC 120
Query: 121 APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL 180
APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL
Sbjct: 121 APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL 180
Query: 181 EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV 240
EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV
Sbjct: 181 EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV 240
Query: 241 SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL 300
SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL
Sbjct: 241 SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL 300
Query: 301 CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGE--------------------------- 333
CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGE
Sbjct: 301 CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGEVMQHAWVEGNSSVKCDRCHKSIKCYQS 360
Query: 334 ------------FHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGEL 381
FHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGEL
Sbjct: 361 VTARHCVWCRMTFHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGEL 420
Query: 382 VMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFR 441
VMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFR
Sbjct: 421 VMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFR 480
Query: 442 DTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSL 501
DTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSL
Sbjct: 481 DTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSL 540
Query: 502 TKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
TKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMRE
Sbjct: 541 TKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMRE 600
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI 621
KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI
Sbjct: 601 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI 660
Query: 622 PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY 681
PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY
Sbjct: 661 PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY 720
Query: 682 TGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSF 741
TGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSF
Sbjct: 721 TGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSF 780
Query: 742 FSLRRKSRSKD 752
FSLRRKSRSKD
Sbjct: 781 FSLRRKSRSKD 791
>gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens]
Length = 766
Score = 1475 bits (3819), Expect = 0.0
Identities = 727/791 (91%), Positives = 727/791 (91%), Gaps = 64/791 (8%)
Query: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR
Sbjct: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
Query: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC 120
AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC
Sbjct: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATKADEAC 120
Query: 121 APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL 180
APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL
Sbjct: 121 APDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDKL 180
Query: 181 EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV 240
EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV
Sbjct: 181 EFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFV 240
Query: 241 SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL 300
SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL
Sbjct: 241 SLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGL 300
Query: 301 CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGE--------------------------- 333
CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGE
Sbjct: 301 CCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGEVMQHAWVEGNSSVKCDRCHKSIKCYQS 360
Query: 334 ------------FHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGEL 381
FHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGEL
Sbjct: 361 VTARHCVWCRMTFHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGEL 420
Query: 382 VMQYKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFR 441
VMQYKIIPTPGTHPLLVLVNPKSGGRQGER LNFFR
Sbjct: 421 VMQYKIIPTPGTHPLLVLVNPKSGGRQGER-------------------------LNFFR 455
Query: 442 DTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSL 501
DTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSL
Sbjct: 456 DTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSL 515
Query: 502 TKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
TKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMRE
Sbjct: 516 TKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMRE 575
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI 621
KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI
Sbjct: 576 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI 635
Query: 622 PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY 681
PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY
Sbjct: 636 PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY 695
Query: 682 TGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSF 741
TGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSF
Sbjct: 696 TGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSF 755
Query: 742 FSLRRKSRSKD 752
FSLRRKSRSKD
Sbjct: 756 FSLRRKSRSKD 766
>gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens]
Length = 804
Score = 929 bits (2402), Expect = 0.0
Identities = 469/833 (56%), Positives = 570/833 (68%), Gaps = 119/833 (14%)
Query: 3 EERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDP-------HEPISYDVF 55
+E+W L+P EF QLQKY+EYS+KK+KD L EF+ G L +Y+P ++ I ++ F
Sbjct: 4 QEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGF 63
Query: 56 KLFMRAYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATK 115
KLFM+ +LE +LP + HLF++FS K H + ++ A S + T
Sbjct: 64 KLFMKTFLEAELPDDFTAHLFMSFSNKFPHSSPMVKSKPALLSGGLRMNKGAITPPRTTS 123
Query: 116 ADEACAPDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGR 175
C+P+ V++LKD+VCYLSLLE GR
Sbjct: 124 PANTCSPE----------------------------------VIHLKDIVCYLSLLERGR 149
Query: 176 PQDKLEFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYD 235
P+DKLEFMFRLYD+D NG LD +E++ I++QM+H+A+YLEWD TEL PIL EM++ +DYD
Sbjct: 150 PEDKLEFMFRLYDTDGNGFLDSSELENIISQMMHVAEYLEWDVTELNPILHEMMEEIDYD 209
Query: 236 RDGFVSLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGV 295
DG VSL+EW+ GGMTTIPLLVLLG++++ K DG+H W +KHF KP YCN C ML+GV
Sbjct: 210 HDGTVSLEEWIQGGMTTIPLLVLLGLENN-VKDDGQHVWRLKHFNKPAYCNLCLNMLIGV 268
Query: 296 RKQGLCCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGE---------------------- 333
KQGLCC++CKYTVHERCV+R P C+KTY K+KR+ +
Sbjct: 269 GKQGLCCSFCKYTVHERCVARAPPSCIKTYVKSKRNTDVMHHYWVEGNCPTKCDKCHKTV 328
Query: 334 -----------------FHRKC--ELSTLCDGGELRDHILLPTSICPIT----------- 363
H KC L CD G L+DHIL PT+ICP+
Sbjct: 329 KCYQGLTGLHCVWCQITLHNKCASHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSV 388
Query: 364 ---------RDRPGEKSDGCVSAKGELVMQ---------YKIIPTPGTHPLLVLVNPKSG 405
+++ G + V K ++ ++ P PGTHPLLV VNPKSG
Sbjct: 389 PEERQSTVKKEKSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSG 448
Query: 406 GRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCID 465
G+QGERI RKF YLLNP+QV++L GP PGLNFFRD PDFRVLACGGDGTVGW+LDCI+
Sbjct: 449 GKQGERIYRKFQYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIE 508
Query: 466 KANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIP 525
KAN KHPPVA+LPLGTGNDLARCLRWGGGYEG +L KILKDIE S +MLDRW EVIP
Sbjct: 509 KANVGKHPPVAILPLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIP 568
Query: 526 REEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSET 585
++ E GD VPYSI+NNYFSIGVDASIAHRFH+MREKHPEKFNSRMKNK WYFEFGTSET
Sbjct: 569 NDKDEKGDPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSET 628
Query: 586 FAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESR 645
F+ATCKKLH+ +E+ECDGV +DL NI LEGIAILNIPSM+GG+NLWGE+KK R+ R +
Sbjct: 629 FSATCKKLHESVEIECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEK 688
Query: 646 KG------VTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTI 699
KG VTD KELKF QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQC+ V I
Sbjct: 689 KGSDKRTTVTDAKELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVI 748
Query: 700 RTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQKSSFF-SLRRKSRSK 751
RT+K LPMQ+DGEPWMQ CTIKITHKNQAPM+MGPP K+ F SL +++R++
Sbjct: 749 RTSKSLPMQIDGEPWMQTPCTIKITHKNQAPMLMGPPPKTGLFCSLVKRTRNR 801
>gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens]
Length = 773
Score = 891 bits (2303), Expect = 0.0
Identities = 449/802 (55%), Positives = 544/802 (67%), Gaps = 118/802 (14%)
Query: 3 EERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDP-------HEPISYDVF 55
+E+W L+P EF QLQKY+EYS+KK+KD L EF+ G L +Y+P ++ I ++ F
Sbjct: 4 QEKWAHLSPSEFSQLQKYAEYSTKKLKDVLEEFHGNGVLAKYNPEGKQDILNQTIDFEGF 63
Query: 56 KLFMRAYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADTNIQNADNATK 115
KLFM+ +LE +LP + HLF++FS K H + ++ A S + T
Sbjct: 64 KLFMKTFLEAELPDDFTAHLFMSFSNKFPHSSPMVKSKPALLSGGLRMNKGAITPPRTTS 123
Query: 116 ADEACAPDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGR 175
C+P+ V++LKD+VCYLSLLE GR
Sbjct: 124 PANTCSPE----------------------------------VIHLKDIVCYLSLLERGR 149
Query: 176 PQDKLEFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYD 235
P+DKLEFMFRLYD+D NG LD +E++ I++QM+H+A+YLEWD TEL PIL EM++ +DYD
Sbjct: 150 PEDKLEFMFRLYDTDGNGFLDSSELENIISQMMHVAEYLEWDVTELNPILHEMMEEIDYD 209
Query: 236 RDGFVSLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGV 295
DG VSL+EW+ GGMTTIPLLVLLG++++ K DG+H W +KHF KP YCN C ML+GV
Sbjct: 210 HDGTVSLEEWIQGGMTTIPLLVLLGLENN-VKDDGQHVWRLKHFNKPAYCNLCLNMLIGV 268
Query: 296 RKQGLCCTYCKYTVHERCVSRNIPGCVKTYSKAKRSGE---------------------- 333
KQGLCC++CKYTVHERCV+R P C+KTY K+KR+ +
Sbjct: 269 GKQGLCCSFCKYTVHERCVARAPPSCIKTYVKSKRNTDVMHHYWVEGNCPTKCDKCHKTV 328
Query: 334 -----------------FHRKC--ELSTLCDGGELRDHILLPTSICPIT----------- 363
H KC L CD G L+DHIL PT+ICP+
Sbjct: 329 KCYQGLTGLHCVWCQITLHNKCASHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSV 388
Query: 364 ---------RDRPGEKSDGCVSAKGELVMQ---------YKIIPTPGTHPLLVLVNPKSG 405
+++ G + V K ++ ++ P PGTHPLLV VNPKSG
Sbjct: 389 PEERQSTVKKEKSGSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSG 448
Query: 406 GRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCID 465
G+QGERI RKF YLLNP+QV++L GP PGLNFFRD PDFRVLACGGDGTVGW+LDCI+
Sbjct: 449 GKQGERIYRKFQYLLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIE 508
Query: 466 KANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIP 525
KAN KHPPVA+LPLGTGNDLARCLRWGGGYEG +L KILKDIE S +MLDRW EVIP
Sbjct: 509 KANVGKHPPVAILPLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIP 568
Query: 526 REEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSET 585
++ E GD VPYSI+NNYFSIGVDASIAHRFH+MREKHPEKFNSRMKNK WYFEFGTSET
Sbjct: 569 NDKDEKGDPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSET 628
Query: 586 FAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESR 645
F+ATCKKLH+ +E+ECDGV +DL NI LEGIAILNIPSM+GG+NLWGE+KK R+ R +
Sbjct: 629 FSATCKKLHESVEIECDGVQIDLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEK 688
Query: 646 KG------VTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTI 699
KG VTD KELKF QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQC+ V I
Sbjct: 689 KGSDKRTTVTDAKELKFASQDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCSCVVI 748
Query: 700 RTNKLLPMQVDGEPWMQPCCTI 721
RT+K LPMQ+DGEPWMQ CT+
Sbjct: 749 RTSKSLPMQIDGEPWMQTPCTV 770
>gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 724 bits (1868), Expect = 0.0
Identities = 394/798 (49%), Positives = 498/798 (62%), Gaps = 124/798 (15%)
Query: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
M +ER + ++P +F QLQKY EYS+KK+ D L F E G + +Y + I Y+ F+ F++
Sbjct: 1 MAKERGL-ISPSDFAQLQKYMEYSTKKVSDVLKLF-EDGEMAKYVQGDAIGYEGFQQFLK 58
Query: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADT-NIQNADNATKADEA 119
++L PRH S + S +T + N N TK
Sbjct: 59 --------------IYLEVDNVPRH---------LSLALFQSFETGHCLNETNVTK---- 91
Query: 120 CAPDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDK 179
VV L DV CY SLLE GRP+DK
Sbjct: 92 -------------------------------------DVVCLNDVSCYFSLLEGGRPEDK 114
Query: 180 LEFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGF 239
LEF F+LYD+D NG+LD +E+D I+ QM+ +A+YL+WD +ELRPIL+EM++ +DYD G
Sbjct: 115 LEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGS 174
Query: 240 VSLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQG 299
VS EWV G TT+PLLVLLG++ + K DG+H W K F +P YCN C + G+ KQG
Sbjct: 175 VSQAEWVRAGATTVPLLVLLGLEMT-LKDDGQHMWRPKRFPRPVYCNLCESSI-GLGKQG 232
Query: 300 LCCTYCKYTVHERCVSRNIPGCVKTYSKAKR---------------SG------------ 332
L C CKYTVH++C + +P V TY+K+++ SG
Sbjct: 233 LSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIY 292
Query: 333 -------------EFHRKC--ELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSA 377
E H C + CD G LRDHIL P+SI P ++ + S
Sbjct: 293 HSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQ 352
Query: 378 K--GELVMQ----YKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNG 431
K +L + +I P P THPLLV VNPKSGG+QG+R+L KF Y+LNP+QVFNL
Sbjct: 353 KTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKD 412
Query: 432 GPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLR 491
GP GL F+D PD R+L CGGDGTVGWIL+ IDKAN PPVAVLPLGTGNDLARCLR
Sbjct: 413 GPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLR 472
Query: 492 WGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDAS 551
WGGGYEG +L KILKD+E S +V +DRW +EVIP++ E D VP+ I+NNYFSIGVDAS
Sbjct: 473 WGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDAS 532
Query: 552 IAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNI 611
IAHRFH+MREK+PEKFNSRMKNKLWYFEF TSE+ +TCKKL + + +E G +DLSN+
Sbjct: 533 IAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNL 592
Query: 612 FLEGIAILNIPSMYGGTNLWGENKKNRA-------VIRESRKGVTDPKELKFCVQDLSDQ 664
LEGIA+LNIPSM+GG+NLWG+ ++ + + K +TDP LK CV DLSD+
Sbjct: 593 SLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDK 652
Query: 665 LLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKIT 724
LEVVGLEGA+EMGQIYT LK+AGRRLA+C+ +T T K LPMQ+DGEPWMQ CTIKIT
Sbjct: 653 RLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKIT 712
Query: 725 HKNQAPMMMGPPQKSSFF 742
HKNQ PM+MGPP +S+ F
Sbjct: 713 HKNQMPMLMGPPPRSTNF 730
>gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 724 bits (1868), Expect = 0.0
Identities = 394/798 (49%), Positives = 498/798 (62%), Gaps = 124/798 (15%)
Query: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
M +ER + ++P +F QLQKY EYS+KK+ D L F E G + +Y + I Y+ F+ F++
Sbjct: 1 MAKERGL-ISPSDFAQLQKYMEYSTKKVSDVLKLF-EDGEMAKYVQGDAIGYEGFQQFLK 58
Query: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADT-NIQNADNATKADEA 119
++L PRH S + S +T + N N TK
Sbjct: 59 --------------IYLEVDNVPRH---------LSLALFQSFETGHCLNETNVTK---- 91
Query: 120 CAPDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDK 179
VV L DV CY SLLE GRP+DK
Sbjct: 92 -------------------------------------DVVCLNDVSCYFSLLEGGRPEDK 114
Query: 180 LEFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGF 239
LEF F+LYD+D NG+LD +E+D I+ QM+ +A+YL+WD +ELRPIL+EM++ +DYD G
Sbjct: 115 LEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGS 174
Query: 240 VSLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQG 299
VS EWV G TT+PLLVLLG++ + K DG+H W K F +P YCN C + G+ KQG
Sbjct: 175 VSQAEWVRAGATTVPLLVLLGLEMT-LKDDGQHMWRPKRFPRPVYCNLCESSI-GLGKQG 232
Query: 300 LCCTYCKYTVHERCVSRNIPGCVKTYSKAKR---------------SG------------ 332
L C CKYTVH++C + +P V TY+K+++ SG
Sbjct: 233 LSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIY 292
Query: 333 -------------EFHRKC--ELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSA 377
E H C + CD G LRDHIL P+SI P ++ + S
Sbjct: 293 HSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQ 352
Query: 378 K--GELVMQ----YKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNG 431
K +L + +I P P THPLLV VNPKSGG+QG+R+L KF Y+LNP+QVFNL
Sbjct: 353 KTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKD 412
Query: 432 GPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLR 491
GP GL F+D PD R+L CGGDGTVGWIL+ IDKAN PPVAVLPLGTGNDLARCLR
Sbjct: 413 GPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLR 472
Query: 492 WGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDAS 551
WGGGYEG +L KILKD+E S +V +DRW +EVIP++ E D VP+ I+NNYFSIGVDAS
Sbjct: 473 WGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDAS 532
Query: 552 IAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNI 611
IAHRFH+MREK+PEKFNSRMKNKLWYFEF TSE+ +TCKKL + + +E G +DLSN+
Sbjct: 533 IAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNL 592
Query: 612 FLEGIAILNIPSMYGGTNLWGENKKNRA-------VIRESRKGVTDPKELKFCVQDLSDQ 664
LEGIA+LNIPSM+GG+NLWG+ ++ + + K +TDP LK CV DLSD+
Sbjct: 593 SLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDK 652
Query: 665 LLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKIT 724
LEVVGLEGA+EMGQIYT LK+AGRRLA+C+ +T T K LPMQ+DGEPWMQ CTIKIT
Sbjct: 653 RLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKIT 712
Query: 725 HKNQAPMMMGPPQKSSFF 742
HKNQ PM+MGPP +S+ F
Sbjct: 713 HKNQMPMLMGPPPRSTNF 730
>gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 724 bits (1868), Expect = 0.0
Identities = 394/798 (49%), Positives = 498/798 (62%), Gaps = 124/798 (15%)
Query: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
M +ER + ++P +F QLQKY EYS+KK+ D L F E G + +Y + I Y+ F+ F++
Sbjct: 1 MAKERGL-ISPSDFAQLQKYMEYSTKKVSDVLKLF-EDGEMAKYVQGDAIGYEGFQQFLK 58
Query: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADT-NIQNADNATKADEA 119
++L PRH S + S +T + N N TK
Sbjct: 59 --------------IYLEVDNVPRH---------LSLALFQSFETGHCLNETNVTK---- 91
Query: 120 CAPDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDK 179
VV L DV CY SLLE GRP+DK
Sbjct: 92 -------------------------------------DVVCLNDVSCYFSLLEGGRPEDK 114
Query: 180 LEFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGF 239
LEF F+LYD+D NG+LD +E+D I+ QM+ +A+YL+WD +ELRPIL+EM++ +DYD G
Sbjct: 115 LEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGS 174
Query: 240 VSLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQG 299
VS EWV G TT+PLLVLLG++ + K DG+H W K F +P YCN C + G+ KQG
Sbjct: 175 VSQAEWVRAGATTVPLLVLLGLEMT-LKDDGQHMWRPKRFPRPVYCNLCESSI-GLGKQG 232
Query: 300 LCCTYCKYTVHERCVSRNIPGCVKTYSKAKR---------------SG------------ 332
L C CKYTVH++C + +P V TY+K+++ SG
Sbjct: 233 LSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIY 292
Query: 333 -------------EFHRKC--ELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSA 377
E H C + CD G LRDHIL P+SI P ++ + S
Sbjct: 293 HSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQ 352
Query: 378 K--GELVMQ----YKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNG 431
K +L + +I P P THPLLV VNPKSGG+QG+R+L KF Y+LNP+QVFNL
Sbjct: 353 KTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKD 412
Query: 432 GPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLR 491
GP GL F+D PD R+L CGGDGTVGWIL+ IDKAN PPVAVLPLGTGNDLARCLR
Sbjct: 413 GPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLR 472
Query: 492 WGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDAS 551
WGGGYEG +L KILKD+E S +V +DRW +EVIP++ E D VP+ I+NNYFSIGVDAS
Sbjct: 473 WGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDAS 532
Query: 552 IAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNI 611
IAHRFH+MREK+PEKFNSRMKNKLWYFEF TSE+ +TCKKL + + +E G +DLSN+
Sbjct: 533 IAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNL 592
Query: 612 FLEGIAILNIPSMYGGTNLWGENKKNRA-------VIRESRKGVTDPKELKFCVQDLSDQ 664
LEGIA+LNIPSM+GG+NLWG+ ++ + + K +TDP LK CV DLSD+
Sbjct: 593 SLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDK 652
Query: 665 LLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKIT 724
LEVVGLEGA+EMGQIYT LK+AGRRLA+C+ +T T K LPMQ+DGEPWMQ CTIKIT
Sbjct: 653 RLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKIT 712
Query: 725 HKNQAPMMMGPPQKSSFF 742
HKNQ PM+MGPP +S+ F
Sbjct: 713 HKNQMPMLMGPPPRSTNF 730
>gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 724 bits (1868), Expect = 0.0
Identities = 394/798 (49%), Positives = 498/798 (62%), Gaps = 124/798 (15%)
Query: 1 MGEERWVSLTPEEFDQLQKYSEYSSKKIKDALTEFNEGGSLKQYDPHEPISYDVFKLFMR 60
M +ER + ++P +F QLQKY EYS+KK+ D L F E G + +Y + I Y+ F+ F++
Sbjct: 1 MAKERGL-ISPSDFAQLQKYMEYSTKKVSDVLKLF-EDGEMAKYVQGDAIGYEGFQQFLK 58
Query: 61 AYLEVDLPQPLSTHLFLAFSQKPRHETSDHPTEGASNSEANSADT-NIQNADNATKADEA 119
++L PRH S + S +T + N N TK
Sbjct: 59 --------------IYLEVDNVPRH---------LSLALFQSFETGHCLNETNVTK---- 91
Query: 120 CAPDTESNMAEKQAPAEDQVAATPLEPPVPRSSSSESPVVYLKDVVCYLSLLETGRPQDK 179
VV L DV CY SLLE GRP+DK
Sbjct: 92 -------------------------------------DVVCLNDVSCYFSLLEGGRPEDK 114
Query: 180 LEFMFRLYDSDENGLLDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGF 239
LEF F+LYD+D NG+LD +E+D I+ QM+ +A+YL+WD +ELRPIL+EM++ +DYD G
Sbjct: 115 LEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGS 174
Query: 240 VSLQEWVHGGMTTIPLLVLLGMDDSGSKGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQG 299
VS EWV G TT+PLLVLLG++ + K DG+H W K F +P YCN C + G+ KQG
Sbjct: 175 VSQAEWVRAGATTVPLLVLLGLEMT-LKDDGQHMWRPKRFPRPVYCNLCESSI-GLGKQG 232
Query: 300 LCCTYCKYTVHERCVSRNIPGCVKTYSKAKR---------------SG------------ 332
L C CKYTVH++C + +P V TY+K+++ SG
Sbjct: 233 LSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIY 292
Query: 333 -------------EFHRKC--ELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSA 377
E H C + CD G LRDHIL P+SI P ++ + S
Sbjct: 293 HSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQ 352
Query: 378 K--GELVMQ----YKIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNG 431
K +L + +I P P THPLLV VNPKSGG+QG+R+L KF Y+LNP+QVFNL
Sbjct: 353 KTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKD 412
Query: 432 GPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLR 491
GP GL F+D PD R+L CGGDGTVGWIL+ IDKAN PPVAVLPLGTGNDLARCLR
Sbjct: 413 GPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLR 472
Query: 492 WGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDAS 551
WGGGYEG +L KILKD+E S +V +DRW +EVIP++ E D VP+ I+NNYFSIGVDAS
Sbjct: 473 WGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDPVPFQIINNYFSIGVDAS 532
Query: 552 IAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNI 611
IAHRFH+MREK+PEKFNSRMKNKLWYFEF TSE+ +TCKKL + + +E G +DLSN+
Sbjct: 533 IAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNL 592
Query: 612 FLEGIAILNIPSMYGGTNLWGENKKNRA-------VIRESRKGVTDPKELKFCVQDLSDQ 664
LEGIA+LNIPSM+GG+NLWG+ ++ + + K +TDP LK CV DLSD+
Sbjct: 593 SLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDK 652
Query: 665 LLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKIT 724
LEVVGLEGA+EMGQIYT LK+AGRRLA+C+ +T T K LPMQ+DGEPWMQ CTIKIT
Sbjct: 653 RLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKIT 712
Query: 725 HKNQAPMMMGPPQKSSFF 742
HKNQ PM+MGPP +S+ F
Sbjct: 713 HKNQMPMLMGPPPRSTNF 730
>gi|4758156 diacylglycerol kinase, iota [Homo sapiens]
Length = 1065
Score = 270 bits (691), Expect = 3e-72
Identities = 151/363 (41%), Positives = 206/363 (56%), Gaps = 27/363 (7%)
Query: 386 KIIPTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPD 445
K I +P PLLV VNPKSGG QG ++L+ F + LNP+QVF+L GP L +R P+
Sbjct: 367 KPISSPLMKPLLVFVNPKSGGNQGTKVLQMFMWYLNPRQVFDLSQEGPKDALELYRKVPN 426
Query: 446 FRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKIL 505
R+LACGGDGTVGWIL +D+ + PPV VLPLGTGNDLAR L WGGGY ++KIL
Sbjct: 427 LRILACGGDGTVGWILSILDELQLSPQPPVGVLPLGTGNDLARTLNWGGGYTDEPVSKIL 486
Query: 506 KDIEQSPLVMLDRWHLEV-----IPREEVENG-DQVPYSIMNNYFSIGVDASIAHRFHVM 559
+E +V LDRW+L V +P EE+E+G ++P ++ NNYFS+G DA + FH
Sbjct: 487 CQVEDGTVVQLDRWNLHVERNPDLPPEELEDGVCKLPLNVFNNYFSLGFDAHVTLEFHES 546
Query: 560 REKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGV--DLSNIFLEGIA 617
RE +PEKFNSR +NK++Y S+ + + L H+++ CDG + + + + I
Sbjct: 547 REANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVKVVCDGTDLTPKIQELKFQCIV 606
Query: 618 ILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEM 677
LNIP GT WG + F Q D +EV+G A +
Sbjct: 607 FLNIPRYCAGTMPWGNPGDHH----------------DFEPQRHDDGYIEVIGFTMA-SL 649
Query: 678 GQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGPPQ 737
+ G G RL QC V + T K +PMQVDGEP I+I+ +NQA M+ +
Sbjct: 650 AALQVG--GHGERLHQCREVMLLTYKSIPMQVDGEPCRLAPAMIRISLRNQANMVQKSKR 707
Query: 738 KSS 740
++S
Sbjct: 708 RTS 710
>gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]
Length = 1117
Score = 270 bits (689), Expect = 5e-72
Identities = 149/365 (40%), Positives = 204/365 (55%), Gaps = 36/365 (9%)
Query: 389 PTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRV 448
P+P PLLV VNPKSGG QG +I++ F + LNP+QVF+L GGP L +R + R+
Sbjct: 478 PSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRI 537
Query: 449 LACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDI 508
LACGGDGTVGWIL +D+ PPVA+LPLGTGNDLAR L WGGGY ++KIL +
Sbjct: 538 LACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHV 597
Query: 509 EQSPLVMLDRWHLEVIPR-----EEVENG--DQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
E+ +V LDRW L P E+ + G D++P + NNYFS+G DA + FH RE
Sbjct: 598 EEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESRE 657
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGV--DLSNIFLEGIAIL 619
+PEKFNSR +NK++Y S+ + K L HI + CDG+ + + ++ + + L
Sbjct: 658 ANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFL 717
Query: 620 NIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLE----GAM 675
NIP GT WG ++ F Q D LEV+G A+
Sbjct: 718 NIPRYCAGTMPWGHPGEHH----------------DFEPQRHDDGYLEVIGFTMTSLAAL 761
Query: 676 EMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGP 735
++G G RL QC V + T+K +P+QVDGEP I+I +NQA M+
Sbjct: 762 QVG-------GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKA 814
Query: 736 PQKSS 740
++S+
Sbjct: 815 KRRSA 819
>gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens]
Length = 945
Score = 270 bits (689), Expect = 5e-72
Identities = 149/365 (40%), Positives = 204/365 (55%), Gaps = 36/365 (9%)
Query: 389 PTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRV 448
P+P PLLV VNPKSGG QG +I++ F + LNP+QVF+L GGP L +R + R+
Sbjct: 306 PSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRI 365
Query: 449 LACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDI 508
LACGGDGTVGWIL +D+ PPVA+LPLGTGNDLAR L WGGGY ++KIL +
Sbjct: 366 LACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHV 425
Query: 509 EQSPLVMLDRWHLEVIPR-----EEVENG--DQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
E+ +V LDRW L P E+ + G D++P + NNYFS+G DA + FH RE
Sbjct: 426 EEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESRE 485
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGV--DLSNIFLEGIAIL 619
+PEKFNSR +NK++Y S+ + K L HI + CDG+ + + ++ + + L
Sbjct: 486 ANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFL 545
Query: 620 NIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLE----GAM 675
NIP GT WG ++ F Q D LEV+G A+
Sbjct: 546 NIPRYCAGTMPWGHPGEHH----------------DFEPQRHDDGYLEVIGFTMTSLAAL 589
Query: 676 EMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGP 735
++G G RL QC V + T+K +P+QVDGEP I+I +NQA M+
Sbjct: 590 QVG-------GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKA 642
Query: 736 PQKSS 740
++S+
Sbjct: 643 KRRSA 647
>gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]
Length = 929
Score = 270 bits (689), Expect = 5e-72
Identities = 149/365 (40%), Positives = 204/365 (55%), Gaps = 36/365 (9%)
Query: 389 PTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRV 448
P+P PLLV VNPKSGG QG +I++ F + LNP+QVF+L GGP L +R + R+
Sbjct: 290 PSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRI 349
Query: 449 LACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDI 508
LACGGDGTVGWIL +D+ PPVA+LPLGTGNDLAR L WGGGY ++KIL +
Sbjct: 350 LACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHV 409
Query: 509 EQSPLVMLDRWHLEVIPR-----EEVENG--DQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
E+ +V LDRW L P E+ + G D++P + NNYFS+G DA + FH RE
Sbjct: 410 EEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESRE 469
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGV--DLSNIFLEGIAIL 619
+PEKFNSR +NK++Y S+ + K L HI + CDG+ + + ++ + + L
Sbjct: 470 ANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFL 529
Query: 620 NIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLE----GAM 675
NIP GT WG ++ F Q D LEV+G A+
Sbjct: 530 NIPRYCAGTMPWGHPGEHH----------------DFEPQRHDDGYLEVIGFTMTSLAAL 573
Query: 676 EMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGP 735
++G G RL QC V + T+K +P+QVDGEP I+I +NQA M+
Sbjct: 574 QVG-------GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKA 626
Query: 736 PQKSS 740
++S+
Sbjct: 627 KRRSA 631
>gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens]
Length = 895
Score = 270 bits (689), Expect = 5e-72
Identities = 149/365 (40%), Positives = 204/365 (55%), Gaps = 36/365 (9%)
Query: 389 PTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRV 448
P+P PLLV VNPKSGG QG +I++ F + LNP+QVF+L GGP L +R + R+
Sbjct: 256 PSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRI 315
Query: 449 LACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDI 508
LACGGDGTVGWIL +D+ PPVA+LPLGTGNDLAR L WGGGY ++KIL +
Sbjct: 316 LACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHV 375
Query: 509 EQSPLVMLDRWHLEVIPR-----EEVENG--DQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
E+ +V LDRW L P E+ + G D++P + NNYFS+G DA + FH RE
Sbjct: 376 EEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESRE 435
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGV--DLSNIFLEGIAIL 619
+PEKFNSR +NK++Y S+ + K L HI + CDG+ + + ++ + + L
Sbjct: 436 ANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFL 495
Query: 620 NIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLE----GAM 675
NIP GT WG ++ F Q D LEV+G A+
Sbjct: 496 NIPRYCAGTMPWGHPGEHH----------------DFEPQRHDDGYLEVIGFTMTSLAAL 539
Query: 676 EMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGP 735
++G G RL QC V + T+K +P+QVDGEP I+I +NQA M+
Sbjct: 540 QVG-------GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKA 592
Query: 736 PQKSS 740
++S+
Sbjct: 593 KRRSA 597
>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
Length = 942
Score = 251 bits (641), Expect = 2e-66
Identities = 143/335 (42%), Positives = 191/335 (57%), Gaps = 31/335 (9%)
Query: 391 PGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLA 450
P + PLLV VNPKSGG +G +L F LLNP QVF+L NGGP PGL+ F P FRVL
Sbjct: 584 PDSCPLLVFVNPKSGGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFSQVPCFRVLV 643
Query: 451 CGGDGTVGWILDCIDKANF---AKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKD 507
CGGDGTVGW+L +++ + P VA+LPLGTGNDL R LRWG GY G +L
Sbjct: 644 CGGDGTVGWVLGALEETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSGEDPFSVLLS 703
Query: 508 IEQSPLVMLDRWHLEVIPRE----EVENGDQVPYSI--MNNYFSIGVDASIAHRFHVMRE 561
++++ V++DRW + + E E + D P I M+NY IG+DA ++ FH RE
Sbjct: 704 VDEADAVLMDRWTILLDAHEAGSAENDTADAEPPKIVQMSNYCGIGIDAELSLDFHQARE 763
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI 621
+ P KF SR+ NK Y G + + + LH I L+ + V+L +I EG+ +NI
Sbjct: 764 EEPGKFTSRLHNKGVYVRVGLQK--ISHSRSLHKQIRLQVERQEVELPSI--EGLIFINI 819
Query: 622 PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY 681
PS G +LWG + R F + D LLEVVG+ G + MGQ+
Sbjct: 820 PSWGSGADLWGSDSDTR-----------------FEKPRMDDGLLEVVGVTGVVHMGQVQ 862
Query: 682 TGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQ 716
GL+S G R+AQ + + K P+QVDGEPW+Q
Sbjct: 863 GGLRS-GIRIAQGSYFRVTLLKATPVQVDGEPWVQ 896
Score = 34.7 bits (78), Expect = 0.33
Identities = 13/43 (30%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCV 314
H++ KPT+C+ C + G+ G C C + HE+C+
Sbjct: 61 HSFRKVTLTKPTFCHLCSDFIWGL--AGFLCDVCNFMSHEKCL 101
>gi|4503313 diacylglycerol kinase epsilon [Homo sapiens]
Length = 567
Score = 242 bits (617), Expect = 1e-63
Identities = 169/472 (35%), Positives = 238/472 (50%), Gaps = 64/472 (13%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGVRKQGLC---CTYCKYTVHERCVSRNIPGCVKTYSKA 328
H W + +YC C G + + LC C +C+ TVH+ C+ ++
Sbjct: 125 HHWIRGNVPLCSYCMVCK-QQCGCQPK-LCDYRCIWCQKTVHDECMKNSLK--------- 173
Query: 329 KRSGEFHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKII 388
+ CD GE ++ I+ P+ + I + R +K+D V A +L Q+
Sbjct: 174 ------------NEKCDFGEFKNLIIPPSYLTSINQMRKDKKTDYEVLAS-KLGKQWT-- 218
Query: 389 PTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDF-- 446
PL++L N +SG GE +L +F LLNP QVF++ P L P +
Sbjct: 219 ------PLIILANSRSGTNMGEGLLGEFRILLNPVQVFDVTKTPPIKALQLCTLLPYYSA 272
Query: 447 RVLACGGDGTVGWILDCID----KANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGG-SL 501
RVL CGGDGTVGW+LD +D K P VAVLPLGTGNDL+ L WG GY G +
Sbjct: 273 RVLVCGGDGTVGWVLDAVDDMKIKGQEKYIPQVAVLPLGTGNDLSNTLGWGTGYAGEIPV 332
Query: 502 TKILKDIEQSPLVMLDRWHLEVIPREEVENGDQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
++L+++ ++ + LDRW ++V + ++ MNNYFS+G DA +A FH RE
Sbjct: 333 AQVLRNVMEADGIKLDRWKVQVTNKGYYNLRKPKEFT-MNNYFSVGPDALMALNFHAHRE 391
Query: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGVDLSNIFLEGIAILNI 621
K P F+SR+ NK Y +GT + CK L+ +ELE DG V L + LEGI +LNI
Sbjct: 392 KAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKVELELDGERVALPS--LEGIIVLNI 449
Query: 622 PSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLEGAMEMGQIY 681
GG LW +G+ D + + D LLEVVG+ G+ QI
Sbjct: 450 GYWGGGCRLW--------------EGMGDE---TYPLARHDDGLLEVVGVYGSFHCAQIQ 492
Query: 682 TGLKSAGRRLAQCASV-TIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMM 732
L + R+ Q +V I ++PMQVDGEPW Q CT+ ITHK A M+
Sbjct: 493 VKLANP-FRIGQAHTVRLILKCSMMPMQVDGEPWAQGPCTVTITHKTHAMML 543
>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
Length = 1164
Score = 169 bits (427), Expect = 1e-41
Identities = 107/296 (36%), Positives = 136/296 (45%), Gaps = 54/296 (18%)
Query: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGCVKT----- 324
G H W +PT+CN C L GV GL C CK+ H+RC R C T
Sbjct: 174 GMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 233
Query: 325 --------------YSKAKRSGEFHRKCELSTLCDGGELR-------------------- 350
+ + + KC + G LR
Sbjct: 234 GKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDL 293
Query: 351 DHILLPTSICPITRDRP----GEKSDGCVSAKGELVMQYKIIPTPGTHPLLVLVNPKSGG 406
H + P C ++ P SDG A + PLLV VN KSG
Sbjct: 294 YHPICPLGQCKVSIIPPIALNSTDSDGFCRATFSFCVS----------PLLVFVNSKSGD 343
Query: 407 RQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDK 466
QG + LR+F LLNP QVF+L NGGP GL F+ +FR+L CGGDG+VGW+L IDK
Sbjct: 344 NQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDK 403
Query: 467 ANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGS-LTKILKDIEQSPLVMLDRWHL 521
N K + VLPLGTGNDLAR L WGG Y+ + L +IL+ +E++ MLDRW +
Sbjct: 404 LNLNKQCQLGVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSI 459
Score = 146 bits (369), Expect = 6e-35
Identities = 83/196 (42%), Positives = 114/196 (58%), Gaps = 21/196 (10%)
Query: 539 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 598
+MNNYF IG+DA I+ F+ RE+HPEK SR KN +WY GT E + K L ++
Sbjct: 770 VMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQ 829
Query: 599 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 658
LECDG + L + L+GIA+LNIPS GGTN WG K++ F
Sbjct: 830 LECDGQYIPLPS--LQGIAVLNIPSYAGGTNFWGGTKEDDI----------------FAA 871
Query: 659 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASV--TIRTNKLLPMQVDGEPWMQ 716
D++LEVV + +M+M + +K R+AQC +V TI ++ +P+QVDGE W+Q
Sbjct: 872 PSFDDKILEVVAIFDSMQMA-VSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQ 930
Query: 717 PCCTIKITHKNQAPMM 732
P IKI HKN+A M+
Sbjct: 931 PPGIIKIVHKNRAQML 946
>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
Length = 1220
Score = 169 bits (427), Expect = 1e-41
Identities = 107/296 (36%), Positives = 136/296 (45%), Gaps = 54/296 (18%)
Query: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGCVKT----- 324
G H W +PT+CN C L GV GL C CK+ H+RC R C T
Sbjct: 174 GMHNWYACSHARPTFCNVCRESLSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 233
Query: 325 --------------YSKAKRSGEFHRKCELSTLCDGGELR-------------------- 350
+ + + KC + G LR
Sbjct: 234 GKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWKCLWCKTMVHTACKDL 293
Query: 351 DHILLPTSICPITRDRP----GEKSDGCVSAKGELVMQYKIIPTPGTHPLLVLVNPKSGG 406
H + P C ++ P SDG A + PLLV VN KSG
Sbjct: 294 YHPICPLGQCKVSIIPPIALNSTDSDGFCRATFSFCVS----------PLLVFVNSKSGD 343
Query: 407 RQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDK 466
QG + LR+F LLNP QVF+L NGGP GL F+ +FR+L CGGDG+VGW+L IDK
Sbjct: 344 NQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDK 403
Query: 467 ANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGS-LTKILKDIEQSPLVMLDRWHL 521
N K + VLPLGTGNDLAR L WGG Y+ + L +IL+ +E++ MLDRW +
Sbjct: 404 LNLNKQCQLGVLPLGTGNDLARVLGWGGSYDDDTQLPQILEKLERASTKMLDRWSI 459
Score = 146 bits (369), Expect = 6e-35
Identities = 83/196 (42%), Positives = 114/196 (58%), Gaps = 21/196 (10%)
Query: 539 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 598
+MNNYF IG+DA I+ F+ RE+HPEK SR KN +WY GT E + K L ++
Sbjct: 770 VMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQ 829
Query: 599 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 658
LECDG + L + L+GIA+LNIPS GGTN WG K++ F
Sbjct: 830 LECDGQYIPLPS--LQGIAVLNIPSYAGGTNFWGGTKEDDI----------------FAA 871
Query: 659 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASV--TIRTNKLLPMQVDGEPWMQ 716
D++LEVV + +M+M + +K R+AQC +V TI ++ +P+QVDGE W+Q
Sbjct: 872 PSFDDKILEVVAIFDSMQMA-VSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQ 930
Query: 717 PCCTIKITHKNQAPMM 732
P IKI HKN+A M+
Sbjct: 931 PPGIIKIVHKNRAQML 946
>gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo
sapiens]
Length = 1170
Score = 167 bits (423), Expect = 3e-41
Identities = 111/301 (36%), Positives = 138/301 (45%), Gaps = 67/301 (22%)
Query: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSR------------- 316
G H W +PTYCN C L GV GL C CK+ H+RC R
Sbjct: 118 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 177
Query: 317 --------------------NIPG------CVKTYSKAKRSGEF---------HRKCE-- 339
N+P C KT R ++ H C+
Sbjct: 178 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 237
Query: 340 LSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVL 399
L T C G + ++ PT++ I SDG A P T PLLV
Sbjct: 238 LLTKCPLGLCKVSVIPPTALNSID-------SDGFWKAS---------CPPSCTSPLLVF 281
Query: 400 VNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGW 459
VN KSG QG + LR+F LLNP QVF+L NGGP GL F+ FR+L CGGDG+VGW
Sbjct: 282 VNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGW 341
Query: 460 ILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGS-LTKILKDIEQSPLVMLDR 518
+L ID N K + VLPLGTGNDLAR L WG + + L +IL+ +E++ MLDR
Sbjct: 342 VLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDR 401
Query: 519 W 519
W
Sbjct: 402 W 402
Score = 140 bits (354), Expect = 3e-33
Identities = 80/193 (41%), Positives = 112/193 (58%), Gaps = 21/193 (10%)
Query: 539 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 598
+MNNYF IG+DA I+ F+ R++HPEK SR KN +WY GT E T K L +
Sbjct: 719 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 778
Query: 599 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 658
LECDG + L + L+GIA+LNIPS GGTN WG K++ F
Sbjct: 779 LECDGRPIPLPS--LQGIAVLNIPSYAGGTNFWGGTKEDDT----------------FAA 820
Query: 659 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASV--TIRTNKLLPMQVDGEPWMQ 716
D++LEVV + G+M+M + ++ R+AQC +V +I ++ +P+QVDGE W+Q
Sbjct: 821 PSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQ 879
Query: 717 PCCTIKITHKNQA 729
P I+I HKN+A
Sbjct: 880 PPGYIRIVHKNRA 892
>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
sapiens]
Length = 1214
Score = 167 bits (423), Expect = 3e-41
Identities = 111/301 (36%), Positives = 138/301 (45%), Gaps = 67/301 (22%)
Query: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSR------------- 316
G H W +PTYCN C L GV GL C CK+ H+RC R
Sbjct: 162 GMHNWYACSHARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASI 221
Query: 317 --------------------NIPG------CVKTYSKAKRSGEF---------HRKCE-- 339
N+P C KT R ++ H C+
Sbjct: 222 GKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKES 281
Query: 340 LSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPTPGTHPLLVL 399
L T C G + ++ PT++ I SDG A P T PLLV
Sbjct: 282 LLTKCPLGLCKVSVIPPTALNSID-------SDGFWKAS---------CPPSCTSPLLVF 325
Query: 400 VNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGW 459
VN KSG QG + LR+F LLNP QVF+L NGGP GL F+ FR+L CGGDG+VGW
Sbjct: 326 VNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPHLGLRLFQKFDTFRILVCGGDGSVGW 385
Query: 460 ILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGS-LTKILKDIEQSPLVMLDR 518
+L ID N K + VLPLGTGNDLAR L WG + + L +IL+ +E++ MLDR
Sbjct: 386 VLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGSACDDDTQLPQILEKLERASTKMLDR 445
Query: 519 W 519
W
Sbjct: 446 W 446
Score = 140 bits (354), Expect = 3e-33
Identities = 80/193 (41%), Positives = 112/193 (58%), Gaps = 21/193 (10%)
Query: 539 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 598
+MNNYF IG+DA I+ F+ R++HPEK SR KN +WY GT E T K L +
Sbjct: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
Query: 599 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 658
LECDG + L + L+GIA+LNIPS GGTN WG K++ F
Sbjct: 823 LECDGRPIPLPS--LQGIAVLNIPSYAGGTNFWGGTKEDDT----------------FAA 864
Query: 659 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQCASV--TIRTNKLLPMQVDGEPWMQ 716
D++LEVV + G+M+M + ++ R+AQC +V +I ++ +P+QVDGE W+Q
Sbjct: 865 PSFDDKILEVVAVFGSMQMA-VSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQ 923
Query: 717 PCCTIKITHKNQA 729
P I+I HKN+A
Sbjct: 924 PPGYIRIVHKNRA 936
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 132 bits (332), Expect = 1e-30
Identities = 75/196 (38%), Positives = 108/196 (55%), Gaps = 21/196 (10%)
Query: 539 IMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIE 598
+MNNYF IG+DA I+ F+ R++HP ++NSR+KNK+WY GT E + +KL + +
Sbjct: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
Query: 599 LECDGVGVDLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCV 658
LECDG + L N L+GI +LNI S GG N WG N ++
Sbjct: 917 LECDGETISLPN--LQGIVVLNITSYAGGINFWGSNTAT----------------TEYEA 958
Query: 659 QDLSDQLLEVVGLEGAMEMGQIYTGLKSAGRRLAQC--ASVTIRTNKLLPMQVDGEPWMQ 716
+ D LEVV + G+++M + R+AQC +TI + +P+QVDGE W+Q
Sbjct: 959 PAIDDGKLEVVAIFGSVQMAMSRI-INLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQ 1017
Query: 717 PCCTIKITHKNQAPMM 732
IKI +KN A M+
Sbjct: 1018 RPGLIKIRYKNAAQML 1033
Score = 129 bits (325), Expect = 8e-30
Identities = 86/258 (33%), Positives = 123/258 (47%), Gaps = 42/258 (16%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGVRK-QGLCCTYCKYTVHERCVSRNIPGCVKTYSKAKR 330
H W + + C CH ++ Q C +C TVH+ C R
Sbjct: 399 HQWVEGNMPVSSQCAVCHESCGSYQRLQDFRCLWCNSTVHDDCRRR-------------- 444
Query: 331 SGEFHRKCELSTLCDGGELRDHILLPTSICPITRDRPGEKSDGCVSAKGELVMQYKIIPT 390
F ++C + R ++ PT++ D G+ G+LV+
Sbjct: 445 ---FSKECCFRSH------RSSVIPPTALS----DPKGD---------GQLVVSSDFWNL 482
Query: 391 PGTH----PLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDF 446
+ PLL+ +N KSG QG LRKF LNP QVF+L GGP GL+ F++ F
Sbjct: 483 DWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVFDLLKGGPEAGLSMFKNFARF 542
Query: 447 RVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGY-EGGSLTKIL 505
R+L CGGDG+V W+L ID + +AV+PLGTGNDLAR L WG + + S IL
Sbjct: 543 RILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDLARVLGWGAFWNKSKSPLDIL 602
Query: 506 KDIEQSPLVMLDRWHLEV 523
+EQ+ + +LDRW + +
Sbjct: 603 NRVEQASVRILDRWSVMI 620
Score = 36.2 bits (82), Expect = 0.11
Identities = 13/52 (25%), Positives = 20/52 (38%)
Query: 270 GRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGC 321
G H W + + +CN C + + + + C CK H C R C
Sbjct: 326 GMHCWYSSYSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASKDC 377
>gi|28557781 protein kinase C, eta [Homo sapiens]
Length = 683
Score = 53.1 bits (126), Expect = 9e-07
Identities = 20/50 (40%), Positives = 31/50 (62%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGC 321
H +++ ++K PT+C+ C +L G+ +QGL C CK VH RC + P C
Sbjct: 246 HKFSIHNYKVPTFCDHCGSLLWGIMRQGLQCKICKMNVHIRCQANVAPNC 295
Score = 41.2 bits (95), Expect = 0.004
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGV-RKQGLCCTYCKYTVHERCVSRNIPGC 321
H + + ++PTYC+ C + GV KQG C C VH+RC + C
Sbjct: 172 HKFMATYLRQPTYCSHCREFIWGVFGKQGYQCQVCTCVVHKRCHHLIVTAC 222
>gi|13384594 protein kinase C, gamma [Homo sapiens]
Length = 697
Score = 52.8 bits (125), Expect = 1e-06
Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 3/55 (5%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERC---VSRNIPGCVK 323
H +T + FK+PT+C+ C + G+ KQGL C C + VH RC V+ PG K
Sbjct: 36 HKFTARFFKQPTFCSHCTDFIWGIGKQGLQCQVCSFVVHRRCHEFVTFECPGAGK 90
Score = 47.0 bits (110), Expect = 7e-05
Identities = 18/49 (36%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
Query: 271 RHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIP 319
+H + + + PT+C+ C +L G+ QG+ C+ C+ VH RCV R++P
Sbjct: 100 KHKFRLHSYSSPTFCDHCGSLLYGLVHQGMKCSCCEMNVHRRCV-RSVP 147
>gi|5453976 protein kinase C, theta [Homo sapiens]
Length = 706
Score = 52.4 bits (124), Expect = 2e-06
Identities = 21/66 (31%), Positives = 36/66 (54%), Gaps = 1/66 (1%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGCVKTYSKAKRS 331
H +T F +PT+C+ CH + G+ KQG C C +H++C+ + I C + + R
Sbjct: 160 HEFTATFFPQPTFCSVCHEFVWGLNKQGYQCRQCNAAIHKKCIDKVIAKCTGSAINS-RE 218
Query: 332 GEFHRK 337
FH++
Sbjct: 219 TMFHKE 224
Score = 47.0 bits (110), Expect = 7e-05
Identities = 19/50 (38%), Positives = 29/50 (58%)
Query: 267 KGDGRHAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSR 316
K D H + + ++K PT+C C +L G+ +QGL C C VH RC ++
Sbjct: 227 KIDMPHRFKVYNYKSPTFCEHCGTLLWGLARQGLKCDACGMNVHHRCQTK 276
>gi|4885563 protein kinase C, epsilon [Homo sapiens]
Length = 737
Score = 52.0 bits (123), Expect = 2e-06
Identities = 20/50 (40%), Positives = 30/50 (60%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGVRKQGLCCTYCKYTVHERCVSRNIPGC 321
H + + ++K PT+C+ C +L G+ +QGL C CK VH RC + P C
Sbjct: 243 HKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNC 292
Score = 41.2 bits (95), Expect = 0.004
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 272 HAWTMKHFKKPTYCNFCHIMLMGV-RKQGLCCTYCKYTVHERCVSRNIPGC 321
H + + ++PTYC+ C + GV KQG C C VH+RC I C
Sbjct: 170 HKFMATYLRQPTYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKC 220
>gi|163644313 calcium and integrin binding 1 [Homo sapiens]
Length = 191
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/113 (25%), Positives = 61/113 (53%), Gaps = 3/113 (2%)
Query: 138 QVAATPLEPPVPR--SSSSESPVVYLKDVVCYLSLL-ETGRPQDKLEFMFRLYDSDENGL 194
++ A P + + R S+S + +D + LS+ +T P K + FR++D D++G
Sbjct: 63 ELKANPFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGT 122
Query: 195 LDQAEMDCIVNQMLHIAQYLEWDPTELRPILKEMLQGMDYDRDGFVSLQEWVH 247
L++ ++ +VN + + +E++ ++ +L+ D DRDG ++L E+ H
Sbjct: 123 LNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQH 175
>gi|98985795 neurocalcin delta [Homo sapiens]
Length = 193
Score = 51.6 bits (122), Expect = 3e-06
Identities = 31/108 (28%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 162 KDVVCYLSLLETGRPQDKLEFMFRLYDSDENGLLDQAEMDCIVN---QMLHIAQYLEWDP 218
++ + LS+ G+ + KL++ F +YD D NG + +AEM IV +M+ + D
Sbjct: 83 REFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDE 142
Query: 219 TELRPILKEMLQGMDYDRDGFVSLQEWVHGGMTTIPLLVLLGMDDSGS 266
+ +++ + MD +RDG +SL+E++ G + ++ LL D S +
Sbjct: 143 STPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSA 190
>gi|98985793 neurocalcin delta [Homo sapiens]
Length = 193
Score = 51.6 bits (122), Expect = 3e-06
Identities = 31/108 (28%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 162 KDVVCYLSLLETGRPQDKLEFMFRLYDSDENGLLDQAEMDCIVN---QMLHIAQYLEWDP 218
++ + LS+ G+ + KL++ F +YD D NG + +AEM IV +M+ + D
Sbjct: 83 REFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDE 142
Query: 219 TELRPILKEMLQGMDYDRDGFVSLQEWVHGGMTTIPLLVLLGMDDSGS 266
+ +++ + MD +RDG +SL+E++ G + ++ LL D S +
Sbjct: 143 STPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSA 190
>gi|98985791 neurocalcin delta [Homo sapiens]
Length = 193
Score = 51.6 bits (122), Expect = 3e-06
Identities = 31/108 (28%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 162 KDVVCYLSLLETGRPQDKLEFMFRLYDSDENGLLDQAEMDCIVN---QMLHIAQYLEWDP 218
++ + LS+ G+ + KL++ F +YD D NG + +AEM IV +M+ + D
Sbjct: 83 REFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDE 142
Query: 219 TELRPILKEMLQGMDYDRDGFVSLQEWVHGGMTTIPLLVLLGMDDSGS 266
+ +++ + MD +RDG +SL+E++ G + ++ LL D S +
Sbjct: 143 STPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSA 190
>gi|98985789 neurocalcin delta [Homo sapiens]
Length = 193
Score = 51.6 bits (122), Expect = 3e-06
Identities = 31/108 (28%), Positives = 59/108 (54%), Gaps = 3/108 (2%)
Query: 162 KDVVCYLSLLETGRPQDKLEFMFRLYDSDENGLLDQAEMDCIVN---QMLHIAQYLEWDP 218
++ + LS+ G+ + KL++ F +YD D NG + +AEM IV +M+ + D
Sbjct: 83 REFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQAIYKMVSSVMKMPEDE 142
Query: 219 TELRPILKEMLQGMDYDRDGFVSLQEWVHGGMTTIPLLVLLGMDDSGS 266
+ +++ + MD +RDG +SL+E++ G + ++ LL D S +
Sbjct: 143 STPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKSDPSIVRLLQCDPSSA 190
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.422
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,250,939
Number of Sequences: 37866
Number of extensions: 1607971
Number of successful extensions: 4667
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 49
Number of HSP's that attempted gapping in prelim test: 4335
Number of HSP's gapped (non-prelim): 269
length of query: 752
length of database: 18,247,518
effective HSP length: 110
effective length of query: 642
effective length of database: 14,082,258
effective search space: 9040809636
effective search space used: 9040809636
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.