Search of human proteins with 36030883

Search of human proteins with 36030883

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|36030883 RP42 homolog [Homo sapiens]
         (259 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|36030883 RP42 homolog [Homo sapiens]                               531   e-151
gi|62122952 DCN1, defective in cullin neddylation 1, domain cont...   438   e-123
gi|27735047 DCN1, defective in cullin neddylation 1, domain cont...   167   1e-41
gi|14150015 DCN1, defective in cullin neddylation 1, domain cont...   140   8e-34
gi|94536778 DCN1, defective in cullin neddylation 1, domain cont...   135   5e-32
gi|94536780 DCN1, defective in cullin neddylation 1, domain cont...   107   1e-23
gi|188528641 SEC14 and spectrin domains 1 [Homo sapiens]               31   1.2  
gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]      28   8.0  
gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]      28   8.0  
gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo...    28   8.0  

>gi|36030883 RP42 homolog [Homo sapiens]
          Length = 259

 Score =  531 bits (1369), Expect = e-151
 Identities = 259/259 (100%), Positives = 259/259 (100%)

Query: 1   MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL 60
           MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL
Sbjct: 1   MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL 60

Query: 61  DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ 120
           DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ
Sbjct: 61  DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ 120

Query: 121 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA 180
           EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA
Sbjct: 121 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA 180

Query: 181 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI 240
           YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI
Sbjct: 181 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI 240

Query: 241 DDFVEFARPQIAGTKSTTV 259
           DDFVEFARPQIAGTKSTTV
Sbjct: 241 DDFVEFARPQIAGTKSTTV 259


>gi|62122952 DCN1, defective in cullin neddylation 1, domain
           containing 2 [Homo sapiens]
          Length = 259

 Score =  438 bits (1127), Expect = e-123
 Identities = 201/255 (78%), Positives = 234/255 (91%)

Query: 1   MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSL 60
           M+KLKSSQKDKVRQFM  TQ+ E+TA+ CL+QN+W+LD ATD+FFQNP+   RES++ ++
Sbjct: 1   MHKLKSSQKDKVRQFMACTQAGERTAIYCLTQNEWRLDEATDSFFQNPDSLHRESMRNAV 60

Query: 61  DRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQ 120
           D+KKLE+LY RYKDPQDENKIG+DGIQQFCDDL+LDPASISVL+IAWKFRAATQCEFS++
Sbjct: 61  DKKKLERLYGRYKDPQDENKIGVDGIQQFCDDLSLDPASISVLVIAWKFRAATQCEFSRK 120

Query: 121 EFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIA 180
           EF+DGMTELGCDS+EKLKA +P++EQELK+  +FKDFYQFTF FAKNPGQKGLDLEMA+A
Sbjct: 121 EFLDGMTELGCDSMEKLKALLPRLEQELKDTAKFKDFYQFTFTFAKNPGQKGLDLEMAVA 180

Query: 181 YWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLI 240
           YW LVL+GRFKFLDLWN FL+EHHKRSIP+DTWNLLLDF  MIADDMSNYDEEGAWPVLI
Sbjct: 181 YWKLVLSGRFKFLDLWNTFLMEHHKRSIPRDTWNLLLDFGNMIADDMSNYDEEGAWPVLI 240

Query: 241 DDFVEFARPQIAGTK 255
           DDFVE+ARP + G K
Sbjct: 241 DDFVEYARPVVTGGK 255


>gi|27735047 DCN1, defective in cullin neddylation 1, domain
           containing 3 [Homo sapiens]
          Length = 304

 Score =  167 bits (422), Expect = 1e-41
 Identities = 83/189 (43%), Positives = 122/189 (64%), Gaps = 6/189 (3%)

Query: 63  KKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEF 122
           ++LE+L+ RYKD + E+ I  +G+++FC+DL +DP    VL++AWKF+AAT C+F+++EF
Sbjct: 89  QRLEELFRRYKDER-EDAILEEGMERFCNDLCVDPTEFRVLLLAWKFQAATMCKFTRKEF 147

Query: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFA--KNPGQKGLDLEMAIA 180
            DG   +  DSI+ + A+ P +  E K+  +FKD Y+FTF F      GQ+ L  E+AIA
Sbjct: 148 FDGCKAISADSIDGICARFPSLLTEAKQEDKFKDLYRFTFQFGLDSEEGQRSLHREIAIA 207

Query: 181 YWNLVL-NGRFKFLDLWNKFLLEHHK--RSIPKDTWNLLLDFSTMIADDMSNYDEEGAWP 237
            W LV        LD W  FL E+    + I +DTWN+ L+F+ +I  D+SNY E+ AWP
Sbjct: 208 LWKLVFTQNNPPVLDQWLNFLTENPSGIKGISRDTWNMFLNFTQVIGPDLSNYSEDEAWP 267

Query: 238 VLIDDFVEF 246
            L D FVE+
Sbjct: 268 SLFDTFVEW 276


>gi|14150015 DCN1, defective in cullin neddylation 1, domain
           containing 5 [Homo sapiens]
          Length = 237

 Score =  140 bits (354), Expect = 8e-34
 Identities = 65/186 (34%), Positives = 117/186 (62%), Gaps = 2/186 (1%)

Query: 63  KKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEF 122
           KK    +  Y  P +   +G +G+++FC+D+ ++P +I +L++AWK  A +   F+K+E+
Sbjct: 49  KKCLAWFYEYAGPDEV--VGPEGMEKFCEDIGVEPENIIMLVLAWKLEAESMGFFTKEEW 106

Query: 123 MDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYW 182
           + GMT L CD  EKL+ +   +  +L +   FK+ Y++ F+FA++  Q+ LD++ A +  
Sbjct: 107 LKGMTSLQCDCTEKLQNKFDFLRSQLNDISSFKNIYRYAFDFARDKDQRSLDIDTAKSML 166

Query: 183 NLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDD 242
            L+L   +    ++ ++L +   R + KD W  +L+FS  +  D+SNYDE+GAWPVL+D+
Sbjct: 167 ALLLGRTWPLFSVFYQYLEQSKYRVMNKDQWYNVLEFSRTVHADLSNYDEDGAWPVLLDE 226

Query: 243 FVEFAR 248
           FVE+ +
Sbjct: 227 FVEWQK 232


>gi|94536778 DCN1, defective in cullin neddylation 1, domain
           containing 4 isoform 1 [Homo sapiens]
          Length = 292

 Score =  135 bits (339), Expect = 5e-32
 Identities = 63/175 (36%), Positives = 109/175 (62%)

Query: 72  YKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGC 131
           Y+    ++ +G +G+++FC+D+ ++P ++ +L++AWK  A     F+ QE++ GMT L C
Sbjct: 111 YEYAGTDDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQC 170

Query: 132 DSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFK 191
           D+ EKL+  +  +   L +   FK  Y++ F+FA+   Q+ LD+  A     L+L   + 
Sbjct: 171 DTTEKLRNTLDYLRSFLNDSTNFKLIYRYAFDFAREKDQRSLDINTAKCMLGLLLGKIWP 230

Query: 192 FLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEF 246
              ++++FL +   + I KD W  +L+FS  I  D+SNYDE+GAWPVL+D+FVE+
Sbjct: 231 LFPVFHQFLEQSKYKVINKDQWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEW 285


>gi|94536780 DCN1, defective in cullin neddylation 1, domain
           containing 4 isoform 2 [Homo sapiens]
          Length = 257

 Score =  107 bits (267), Expect = 1e-23
 Identities = 57/175 (32%), Positives = 94/175 (53%), Gaps = 35/175 (20%)

Query: 72  YKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGC 131
           Y+    ++ +G +G+++FC+D+ ++P ++ +L++AWK  A     F+ QE++ GMT L C
Sbjct: 111 YEYAGTDDVVGPEGMEKFCEDIGVEPENVVMLVLAWKLDAQNMGYFTLQEWLKGMTSLQC 170

Query: 132 DSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLDLEMAIAYWNLVLNGRFK 191
           D+ EKL+  +  +   L +   FK  Y++ F+FA+    K             V+N    
Sbjct: 171 DTTEKLRNTLDYLRSFLNDSTNFKLIYRYAFDFARQSKYK-------------VIN---- 213

Query: 192 FLDLWNKFLLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGAWPVLIDDFVEF 246
                             KD W  +L+FS  I  D+SNYDE+GAWPVL+D+FVE+
Sbjct: 214 ------------------KDQWCNVLEFSRTINLDLSNYDEDGAWPVLLDEFVEW 250


>gi|188528641 SEC14 and spectrin domains 1 [Homo sapiens]
          Length = 696

 Score = 30.8 bits (68), Expect = 1.2
 Identities = 28/124 (22%), Positives = 57/124 (45%), Gaps = 10/124 (8%)

Query: 52  IRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISVLIIAWKFRA 111
           +RE  +G LD+   +  +   KD   ENK  +D IQ   +D+ L       ++   + + 
Sbjct: 434 LREKGQGLLDQISNQASWAYGKDVTIENKENVDHIQGVMEDMQLRKQRCEDMVDVRRLKM 493

Query: 112 AT-----QCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQE----LKEPGRFKDFYQFTF 162
                  +CE    + ++ ++EL  D++ K   ++    QE    L++  +F D  Q T+
Sbjct: 494 LQMVQLFKCEEDAAQAVEWLSEL-LDALLKTHIRLGDDAQETKVLLEKHRKFVDVAQSTY 552

Query: 163 NFAK 166
           ++ +
Sbjct: 553 DYGR 556


>gi|35493713 vacuolar protein sorting 13B isoform 5 [Homo sapiens]
          Length = 4022

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 200  LLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGA 235
            L+   K+ +  D W ++L+ S   ADD S+  E G+
Sbjct: 2413 LVNDQKKLVSSDLWRIVLNSSQNGADDQSSASESGS 2448


>gi|35493701 vacuolar protein sorting 13B isoform 1 [Homo sapiens]
          Length = 3997

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 12/36 (33%), Positives = 20/36 (55%)

Query: 200  LLEHHKRSIPKDTWNLLLDFSTMIADDMSNYDEEGA 235
            L+   K+ +  D W ++L+ S   ADD S+  E G+
Sbjct: 2388 LVNDQKKLVSSDLWRIVLNSSQNGADDQSSASESGS 2423


>gi|34932496 butyrophilin, subfamily 3, member A2 precursor [Homo
           sapiens]
          Length = 334

 Score = 28.1 bits (61), Expect = 8.0
 Identities = 19/70 (27%), Positives = 36/70 (51%), Gaps = 9/70 (12%)

Query: 15  FMIFTQSSEKTAVSCLSQNDWKLD----VATDNFFQNPELYIRESVKGSLDRKKLEQLYN 70
           + ++ Q  E TA+S   +++ ++      AT+      E+ +RES++  L RKK++ L  
Sbjct: 268 YFLWRQQKEITALSSEIESEQEMKEMGYAATER-----EISLRESLQEELKRKKIQYLTR 322

Query: 71  RYKDPQDENK 80
             +   D NK
Sbjct: 323 GEESSSDTNK 332


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,355,914
Number of Sequences: 37866
Number of extensions: 388857
Number of successful extensions: 930
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 916
Number of HSP's gapped (non-prelim): 13
length of query: 259
length of database: 18,247,518
effective HSP length: 100
effective length of query: 159
effective length of database: 14,460,918
effective search space: 2299285962
effective search space used: 2299285962
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.