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Search of human proteins with 33519455
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33519455 methionine adenosyltransferase II, beta isoform 2
[Homo sapiens]
(323 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H... 663 0.0
gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H... 642 0.0
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 39 0.006
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 39 0.006
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 33 0.34
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 32 0.58
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 32 0.58
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 32 0.58
gi|4507709 tissue specific transplantation antigen P35B [Homo sa... 30 2.9
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 30 3.8
gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 29 4.9
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 29 4.9
gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens] 29 6.5
gi|122056476 caspase 8 isoform G precursor [Homo sapiens] 28 8.4
gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 28 8.4
gi|4757828 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 5 ... 28 8.4
>gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo
sapiens]
Length = 323
Score = 663 bits (1710), Expect = 0.0
Identities = 323/323 (100%), Positives = 323/323 (100%)
Query: 1 MPEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVN 60
MPEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVN
Sbjct: 1 MPEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVN 60
Query: 61 LLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFL 120
LLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFL
Sbjct: 61 LLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFL 120
Query: 121 IYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEK 180
IYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEK
Sbjct: 121 IYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEK 180
Query: 181 LEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWS 240
LEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWS
Sbjct: 181 LEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWS 240
Query: 241 GNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPF 300
GNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPF
Sbjct: 241 GNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPF 300
Query: 301 RIGIKESLWPFLIDKRWRQTVFH 323
RIGIKESLWPFLIDKRWRQTVFH
Sbjct: 301 RIGIKESLWPFLIDKRWRQTVFH 323
>gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo
sapiens]
Length = 334
Score = 642 bits (1657), Expect = 0.0
Identities = 313/314 (99%), Positives = 314/314 (100%)
Query: 10 QEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHH 69
+EEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHH
Sbjct: 21 EEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHH 80
Query: 70 IIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVF 129
IIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVF
Sbjct: 81 IIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVF 140
Query: 130 DGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVM 189
DGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVM
Sbjct: 141 DGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVM 200
Query: 190 FDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYE 249
FDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYE
Sbjct: 201 FDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKGTFHWSGNEQMTKYE 260
Query: 250 MACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLW 309
MACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLW
Sbjct: 261 MACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKLETLGIGQRTPFRIGIKESLW 320
Query: 310 PFLIDKRWRQTVFH 323
PFLIDKRWRQTVFH
Sbjct: 321 PFLIDKRWRQTVFH 334
>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 38.9 bits (89), Expect = 0.006
Identities = 38/171 (22%), Positives = 78/171 (45%), Gaps = 15/171 (8%)
Query: 2 PEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFE 57
P++ D+E+ N +R V G +G LG+ + ++ + + GF + +F
Sbjct: 23 PKVNADIEKVNQN-QAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFF 81
Query: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAA 115
+L ++ + + + HCA+ P N + ++N + N+ + + A
Sbjct: 82 LGDLCSRQDLYPALKGV--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAG 136
Query: 116 VGAFLIYISSDYVFDGTNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 163
V ++ S+ +F+G + ED+P P++ Y +TK+ E+AVL N
Sbjct: 137 VQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
sapiens]
Length = 373
Score = 38.9 bits (89), Expect = 0.006
Identities = 38/171 (22%), Positives = 78/171 (45%), Gaps = 15/171 (8%)
Query: 2 PEMPEDMEQEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHA----VGCGFRRARPKFE 57
P++ D+E+ N +R V G +G LG+ + ++ + + GF + +F
Sbjct: 23 PKVNADIEKVNQN-QAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVRFF 81
Query: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAA 115
+L ++ + + + HCA+ P N + ++N + N+ + + A
Sbjct: 82 LGDLCSRQDLYPALKGV--NTVFHCAS---PPPSSNNKELFYRVNYIGTKNVIETCKEAG 136
Query: 116 VGAFLIYISSDYVFDGTNPPYREEDIP---APLNLYGKTKLDGEKAVLENN 163
V ++ S+ +F+G + ED+P P++ Y +TK+ E+AVL N
Sbjct: 137 VQKLILTSSASVIFEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGAN 187
>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
Length = 350
Score = 33.1 bits (74), Expect = 0.34
Identities = 30/105 (28%), Positives = 50/105 (47%), Gaps = 4/105 (3%)
Query: 55 KFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEA- 113
KF Q ++ DS+ V + + +++H AA+ D+ + + +NV + L A
Sbjct: 71 KFIQGDICDSHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAH 130
Query: 114 -AAVGAFLIYISSDYVFDGTNPPYREEDIP-APLNLYGKTKLDGE 156
A V F IY+S+D V+ G+ +E P P N Y +K E
Sbjct: 131 EARVEKF-IYVSTDEVYGGSLDKEFDESSPKQPTNPYASSKAAAE 174
>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 32.3 bits (72), Expect = 0.58
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 19 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 57
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
Query: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 117
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
Query: 118 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 159
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 32.3 bits (72), Expect = 0.58
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 19 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 57
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
Query: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 117
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
Query: 118 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 159
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
Length = 348
Score = 32.3 bits (72), Expect = 0.58
Identities = 39/166 (23%), Positives = 66/166 (39%), Gaps = 26/166 (15%)
Query: 19 RVLVTGATGLLGRAVHKEFQQ--------NNWHAVGCG-------FRRARP------KFE 57
+VLVTG G +G E + +N+H G RR + +FE
Sbjct: 4 KVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEFE 63
Query: 58 QVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVG 117
++++LD A+ + + ++H A + +P ++N+ + L + A G
Sbjct: 64 EMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAHG 123
Query: 118 AFLIYISSDYVFDGTNPPYREEDIPAP----LNLYGKTKLDGEKAV 159
+ SS G NP Y D P N YGK+K E+ +
Sbjct: 124 VKNLVFSSSATVYG-NPQYLPLDEAHPTGGCTNPYGKSKFFIEEMI 168
>gi|4507709 tissue specific transplantation antigen P35B [Homo
sapiens]
Length = 321
Score = 30.0 bits (66), Expect = 2.9
Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 9/69 (13%)
Query: 19 RVLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKF---EQVNLLDSNAVHHIIHDFQ 75
R+LVTG +GL+G+A+ K A G G F + +L D+ + Q
Sbjct: 9 RILVTGGSGLVGKAIQKVV------ADGAGLPGEDWVFVSSKDADLTDTAQTRALFEKVQ 62
Query: 76 PHVIVHCAA 84
P ++H AA
Sbjct: 63 PTHVIHLAA 71
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 29.6 bits (65), Expect = 3.8
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 145 LNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEE 183
+NL G T LD + E + AA R+ L+ E+EK E+
Sbjct: 427 MNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQ 465
>gi|116268111 short chain dehydrogenase/reductase family 42E, member
1 [Homo sapiens]
Length = 393
Score = 29.3 bits (64), Expect = 4.9
Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)
Query: 20 VLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARP--------KFEQVNLLDSNAVHHII 71
VL+TG +G G + QN H + F + P KF Q ++ + V
Sbjct: 11 VLITGGSGYFGFRLGCALNQNGVHVI--LFDISSPAQTIPEGIKFIQGDIRHLSDVEKAF 68
Query: 72 HDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVF 129
D + H A+ + + ++NV + N+ + + V + + + +F
Sbjct: 69 QDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIF 128
Query: 130 DGTNPPYREEDIP-APLNL----YGKTKLDGEKAVLENN 163
G +E +P PL+L Y +TK E+ VLE N
Sbjct: 129 GGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 29.3 bits (64), Expect = 4.9
Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 8/99 (8%)
Query: 137 REEDIPAPLNLYGKTKLDGEKAVLENNLGAAVLRIPILYGEVEKLEESAVTVMFDKVQFS 196
R+E A LN KL E+ +L+ LG+ + L E ++E SA+ + D+V
Sbjct: 1822 RQEGEAAALNTV--QKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVALR 1879
Query: 197 NKSANMDHWQQRFPTHVKDVATVCRQLAEKRMLDPSIKG 235
++ +++ +H V R AEK LD ++ G
Sbjct: 1880 RTLDKVE--REKLRSHEDTV----RLSAEKGRLDRTLTG 1912
>gi|109715829 short-chain dehydrogenase/reductase [Homo sapiens]
Length = 260
Score = 28.9 bits (63), Expect = 6.5
Identities = 14/31 (45%), Positives = 18/31 (58%)
Query: 17 NRRVLVTGATGLLGRAVHKEFQQNNWHAVGC 47
+R LVTGA+G +G AV + Q VGC
Sbjct: 11 DRLALVTGASGGIGAAVARALVQQGLKVVGC 41
>gi|122056476 caspase 8 isoform G precursor [Homo sapiens]
Length = 538
Score = 28.5 bits (62), Expect = 8.4
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 16/87 (18%)
Query: 154 DGEKAVLENNLGAAVLRIPI--------LYGEVEKLEESAVTVMFDKVQFSNKSANMDHW 205
D E A++ GA + +P LY E+L+ + S K ++D+
Sbjct: 38 DSETAMVPGKGGADYILLPFKKMDFSRNLYDIGEQLDSEDLA--------SLKFLSLDYI 89
Query: 206 QQRFPTHVKDVATVCRQLAEKRMLDPS 232
QR +KD + ++L EKRML+ S
Sbjct: 90 PQRKQEPIKDALMLFQRLQEKRMLEES 116
>gi|119703749 hydrocephalus inducing isoform a [Homo sapiens]
Length = 5120
Score = 28.5 bits (62), Expect = 8.4
Identities = 12/18 (66%), Positives = 13/18 (72%)
Query: 296 QRTPFRIGIKESLWPFLI 313
Q TPF +GI ES W FLI
Sbjct: 4046 QFTPFHLGITESSWTFLI 4063
>gi|4757828 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 5
[Homo sapiens]
Length = 388
Score = 28.5 bits (62), Expect = 8.4
Identities = 25/96 (26%), Positives = 43/96 (44%), Gaps = 8/96 (8%)
Query: 230 DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDS--PVLGAQRPRNAQLDCS 287
DP+IK HW ++ M ++++A I F HL + P+L QR + A
Sbjct: 144 DPTIKLGGHWKPSDCMPRWKVAILI--PFRNRHEHLPVLFRHLLPMLQRQRLQFAFYVVE 201
Query: 288 KLETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH 323
++ T + F +G +E+ + D W +FH
Sbjct: 202 QVGTQPFNRAMLFNVGFQEA----MKDLDWDCLIFH 233
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,561,383
Number of Sequences: 37866
Number of extensions: 543821
Number of successful extensions: 1087
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1081
Number of HSP's gapped (non-prelim): 17
length of query: 323
length of database: 18,247,518
effective HSP length: 102
effective length of query: 221
effective length of database: 14,385,186
effective search space: 3179126106
effective search space used: 3179126106
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.