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Search of human proteins with 32895365
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32895365 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 4 [Homo sapiens]
(253 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32895365 leukocyte immunoglobulin-like receptor subfamily A m... 530 e-151
gi|32895361 leukocyte immunoglobulin-like receptor subfamily A m... 521 e-148
gi|32895363 leukocyte immunoglobulin-like receptor subfamily A m... 474 e-134
gi|32490553 leukocyte immunoglobulin-like receptor subfamily A m... 466 e-131
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 301 5e-82
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 291 4e-79
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 291 4e-79
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 249 2e-66
gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B... 243 2e-64
gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B... 243 2e-64
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 241 3e-64
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 241 3e-64
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (... 229 1e-60
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 216 2e-56
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 216 2e-56
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 216 2e-56
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 216 2e-56
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A... 216 2e-56
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (... 216 2e-56
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 213 1e-55
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 213 1e-55
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ... 213 1e-55
gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like... 211 4e-55
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 197 6e-51
gi|134133244 killer cell immunoglobulin-like receptor, three dom... 143 2e-34
gi|224586788 natural cytotoxicity triggering receptor 1 isoform ... 140 8e-34
gi|224586786 natural cytotoxicity triggering receptor 1 isoform ... 140 8e-34
gi|4758692 natural cytotoxicity triggering receptor 1 isoform a ... 140 8e-34
gi|134268644 killer cell immunoglobulin-like receptor, three dom... 139 3e-33
gi|143770741 glycoprotein VI (platelet) isoform 1 [Homo sapiens] 138 5e-33
>gi|32895365 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 4 [Homo sapiens]
Length = 253
Score = 530 bits (1365), Expect = e-151
Identities = 253/253 (100%), Positives = 253/253 (100%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
Query: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE
Sbjct: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
Query: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS
Sbjct: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
Query: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQ 240
GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQ
Sbjct: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQ 240
Query: 241 TGCGELYRQGSPC 253
TGCGELYRQGSPC
Sbjct: 241 TGCGELYRQGSPC 253
>gi|32895361 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 3 [Homo sapiens]
Length = 265
Score = 521 bits (1342), Expect = e-148
Identities = 253/265 (95%), Positives = 253/265 (95%), Gaps = 12/265 (4%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLG------------NLSKATLWAEPGSVISRG 48
MAPWSHPSAQLQPVGGDAVSPALMVLLCLG NLSKATLWAEPGSVISRG
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRG 60
Query: 49 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 108
NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS
Sbjct: 61 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 120
Query: 109 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 168
PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK
Sbjct: 121 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 180
Query: 169 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEE 228
LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEE
Sbjct: 181 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEE 240
Query: 229 ATVFSSTIQGSQTGCGELYRQGSPC 253
ATVFSSTIQGSQTGCGELYRQGSPC
Sbjct: 241 ATVFSSTIQGSQTGCGELYRQGSPC 265
>gi|32895363 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 2 [Homo sapiens]
Length = 287
Score = 474 bits (1221), Expect = e-134
Identities = 226/226 (100%), Positives = 226/226 (100%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
Query: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE
Sbjct: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
Query: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS
Sbjct: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
Query: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG
Sbjct: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
>gi|32490553 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 1 [Homo sapiens]
Length = 299
Score = 466 bits (1198), Expect = e-131
Identities = 226/238 (94%), Positives = 226/238 (94%), Gaps = 12/238 (5%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLG------------NLSKATLWAEPGSVISRG 48
MAPWSHPSAQLQPVGGDAVSPALMVLLCLG NLSKATLWAEPGSVISRG
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRG 60
Query: 49 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 108
NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS
Sbjct: 61 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 120
Query: 109 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 168
PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK
Sbjct: 121 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 180
Query: 169 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG
Sbjct: 181 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 238
>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
member 6 [Homo sapiens]
Length = 481
Score = 301 bits (770), Expect = 5e-82
Identities = 154/239 (64%), Positives = 174/239 (72%), Gaps = 12/239 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++PAL LLCLG K TLWAEPGSVIS G+ VTI CQG+LEAQEY+L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
KEGSPEP D NPLEPKNKARFSIPSMT+HHAGRYRC+YYS AGWSEPSDPLELV+TGF
Sbjct: 61 DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
YNKPTLSALPSPVV SG N+TL+CGS+ + F+L +EG+H+L TLDSQ SG FQAL
Sbjct: 121 YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
FPVGPVTPSHRW CY + +VWS PSD LEI SG T+QG G+
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQ 239
Score = 144 bits (362), Expect = 1e-34
Identities = 92/251 (36%), Positives = 130/251 (51%), Gaps = 22/251 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G +K TL A P V++ G ++T+RC
Sbjct: 104 AGWSEPSDPLE-------------LVMTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGY 150
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L+KEG P D+Q +A F + +T H R+ CYYY +P WS P
Sbjct: 151 HHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHP 210
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPLE++ +G KP+L L PV+ G+++TLQCGS + +DRF+L +EG+
Sbjct: 211 SDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGERDF-LQRPG 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE-EATVFSS 234
Q +G QA F +GPV+PSH RCYG+ ++ WS PSD L I ++G+ TV S
Sbjct: 270 QQPQAGLSQANFTLGPVSPSHGGQYRCYGA-HNLSSEWSAPSDPLNILMAGQIYDTVSLS 328
Query: 235 TIQGSQTGCGE 245
G GE
Sbjct: 329 AQPGPTVASGE 339
Score = 129 bits (323), Expect = 3e-30
Identities = 85/228 (37%), Positives = 121/228 (53%), Gaps = 19/228 (8%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WSHPS L+ +L G K +L G V++ G S+T++C +
Sbjct: 207 WSHPSDPLE-------------ILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDR 253
Query: 64 YRLVKEGSPEPWDT--QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPL 119
+ L KEG + Q P ++A F++ ++ H G+YRCY + + WS PSDPL
Sbjct: 254 FVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAHNLSSEWSAPSDPL 313
Query: 120 ELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLT 178
+++ G Y+ +LSA P P V SGENVTL C SR FD F+LT+EG L S +
Sbjct: 314 NILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRS-MY 372
Query: 179 PSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+ ++QA FP+ PVT +H RCYGS + S PS+ LE+ VSG
Sbjct: 373 GAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSG 420
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 291 bits (745), Expect = 4e-79
Identities = 151/239 (63%), Positives = 170/239 (71%), Gaps = 12/239 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++PAL LLCLG K TLWAEPGSVIS G+ VTI CQG+ EAQEYRL
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
KEGSPEP D NPLEPKNKARFSIPSMTEHHAGRYRC+YYS AGWSEPSDPLE+V+TG
Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVV SG N+TL+CGS+ + F+L +EG+H+L TLDSQ S FQAL
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
FPVGPVTPSHRW CY + VWS PSD LEI SG T+QG G+
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQ 239
Score = 139 bits (350), Expect = 2e-33
Identities = 90/251 (35%), Positives = 130/251 (51%), Gaps = 22/251 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ ++ G SK TL A P V++ G ++T+RC
Sbjct: 104 AGWSEPSDPLE-------------MVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGY 150
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L+KEG P D+Q +A F + +T H R+ CYYY +P WS P
Sbjct: 151 HHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHP 210
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPLE++ +G KP+L L PV+ G+++TLQCGS + ++RF+L +EG+
Sbjct: 211 SDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDF-LQRPG 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE-EATVFSS 234
Q +G QA F +GPV+PS+ RCYG+ ++ WS PSD L I ++G+ TV S
Sbjct: 270 QQPQAGLSQANFTLGPVSPSNGGQYRCYGA-HNLSSEWSAPSDPLNILMAGQIYDTVSLS 328
Query: 235 TIQGSQTGCGE 245
G GE
Sbjct: 329 AQPGPTVASGE 339
Score = 126 bits (316), Expect = 2e-29
Identities = 83/228 (36%), Positives = 121/228 (53%), Gaps = 19/228 (8%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WSHPS L+ +L G K +L G V++ G S+T++C +
Sbjct: 207 WSHPSDPLE-------------ILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNR 253
Query: 64 YRLVKEGSPEPWDT--QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPL 119
+ L KEG + Q P ++A F++ ++ + G+YRCY + + WS PSDPL
Sbjct: 254 FVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPL 313
Query: 120 ELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLT 178
+++ G Y+ +LSA P P V SGENVTL C S +FD F+LT+EG L S +
Sbjct: 314 NILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRS-MY 372
Query: 179 PSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+ ++QA FP+ PVT +H RCYGS + S PS+ LE+ VSG
Sbjct: 373 GAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSG 420
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 291 bits (745), Expect = 4e-79
Identities = 151/239 (63%), Positives = 170/239 (71%), Gaps = 12/239 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++PAL LLCLG K TLWAEPGSVIS G+ VTI CQG+ EAQEYRL
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
KEGSPEP D NPLEPKNKARFSIPSMTEHHAGRYRC+YYS AGWSEPSDPLE+V+TG
Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVV SG N+TL+CGS+ + F+L +EG+H+L TLDSQ S FQAL
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
FPVGPVTPSHRW CY + VWS PSD LEI SG T+QG G+
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQ 239
Score = 139 bits (350), Expect = 2e-33
Identities = 90/251 (35%), Positives = 130/251 (51%), Gaps = 22/251 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ ++ G SK TL A P V++ G ++T+RC
Sbjct: 104 AGWSEPSDPLE-------------MVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGY 150
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L+KEG P D+Q +A F + +T H R+ CYYY +P WS P
Sbjct: 151 HHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHP 210
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPLE++ +G KP+L L PV+ G+++TLQCGS + ++RF+L +EG+
Sbjct: 211 SDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDF-LQRPG 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE-EATVFSS 234
Q +G QA F +GPV+PS+ RCYG+ ++ WS PSD L I ++G+ TV S
Sbjct: 270 QQPQAGLSQANFTLGPVSPSNGGQYRCYGA-HNLSSEWSAPSDPLNILMAGQIYDTVSLS 328
Query: 235 TIQGSQTGCGE 245
G GE
Sbjct: 329 AQPGPTVASGE 339
Score = 126 bits (316), Expect = 2e-29
Identities = 83/228 (36%), Positives = 121/228 (53%), Gaps = 19/228 (8%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WSHPS L+ +L G K +L G V++ G S+T++C +
Sbjct: 207 WSHPSDPLE-------------ILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNR 253
Query: 64 YRLVKEGSPEPWDT--QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPL 119
+ L KEG + Q P ++A F++ ++ + G+YRCY + + WS PSDPL
Sbjct: 254 FVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPL 313
Query: 120 ELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLT 178
+++ G Y+ +LSA P P V SGENVTL C S +FD F+LT+EG L S +
Sbjct: 314 NILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRS-MY 372
Query: 179 PSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+ ++QA FP+ PVT +H RCYGS + S PS+ LE+ VSG
Sbjct: 373 GAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSG 420
>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
member 4 [Homo sapiens]
Length = 499
Score = 249 bits (635), Expect = 2e-66
Identities = 132/215 (61%), Positives = 149/215 (69%), Gaps = 1/215 (0%)
Query: 31 NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFS 90
NL K LWAEPG VI+ N VTI CQGTLEAQ YRL KEG+ LE +NK + S
Sbjct: 25 NLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLS 84
Query: 91 IPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQC 150
IPSM HAGRY CYY SPAGWSEPSDPLELVVT Y++PTLSALPSPVVTSG NVTL+C
Sbjct: 85 IPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTLRC 143
Query: 151 GSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHIL 210
SRL RF L EEGDH+LSWTL+S G+FQALFP+GP+T S+R RCYG +
Sbjct: 144 ASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTP 203
Query: 211 QVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
VWSEPSD L++ VSG T+QG GE
Sbjct: 204 YVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
Score = 132 bits (331), Expect = 4e-31
Identities = 90/246 (36%), Positives = 130/246 (52%), Gaps = 22/246 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L + S+ TL A P V++ G +VT+RC L
Sbjct: 104 AGWSEPSDPLE--------------LVVTAYSRPTLSALPSPVVTSGVNVTLRCASRLGL 149
Query: 62 QEYRLVKEGSPEPWDTQNPLEP---KNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L++EG T N + K +A F + +T + G +RCY Y +P WSEP
Sbjct: 150 GRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEP 209
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPL+L+V+G KP+L L PVVT GEN+TLQCGS + + R+ L +EG L
Sbjct: 210 SDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGR 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSST 235
Q +G QA F + PV+ S+ RCYG+ ++ WS PSD L+I ++G+ + S +
Sbjct: 270 Q-PQAGLSQANFTLSPVSRSYGGQYRCYGA-HNVSSEWSAPSDPLDILIAGQISDRPSLS 327
Query: 236 IQGSQT 241
+Q T
Sbjct: 328 VQPGPT 333
Score = 122 bits (306), Expect = 3e-28
Identities = 84/234 (35%), Positives = 123/234 (52%), Gaps = 21/234 (8%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS PS LQ LL G K +L G V++ G ++T++C +
Sbjct: 206 WSEPSDPLQ-------------LLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIR 252
Query: 64 YRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDP 118
Y L KEG+ P+ Q P ++A F++ ++ + G+YRCY + + WS PSDP
Sbjct: 253 YTLYKEGADGLPQRPGRQ-PQAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDP 311
Query: 119 LELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177
L++++ G ++P+LS P P VTSGE VTL C S F+LT+EG L S +
Sbjct: 312 LDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRS-M 370
Query: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATV 231
+ ++QA FP+ PVT +H RCYGSR + S PS+ LE+ VSG T+
Sbjct: 371 YGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETL 424
>gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 2 [Homo sapiens]
Length = 447
Score = 243 bits (619), Expect = 2e-64
Identities = 136/236 (57%), Positives = 153/236 (64%), Gaps = 13/236 (5%)
Query: 21 PALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVK 68
P LLCLG L K TLWAEPGSVIS GNSVTI CQGTLEA+EYRL K
Sbjct: 3 PTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDK 62
Query: 69 EGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYN 128
E SP PWD QNPLEPKNKARFSIPSMTE +AGRYRCYY SP GWS+PSDPLELV+TG Y+
Sbjct: 63 EESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYS 122
Query: 129 KPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFP 188
KPTLSALPSP+VTSG++VTL C SR D F+L +E L S+ + Q QA FP
Sbjct: 123 KPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSE-HGAQQHQAEFP 181
Query: 189 VGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCG 244
+ PVT H RC+ S + S PSD LE+ VSG S + T G
Sbjct: 182 MSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAG 237
>gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 1 [Homo sapiens]
Length = 448
Score = 243 bits (619), Expect = 2e-64
Identities = 136/236 (57%), Positives = 153/236 (64%), Gaps = 13/236 (5%)
Query: 21 PALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVK 68
P LLCLG L K TLWAEPGSVIS GNSVTI CQGTLEA+EYRL K
Sbjct: 3 PTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDK 62
Query: 69 EGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYN 128
E SP PWD QNPLEPKNKARFSIPSMTE +AGRYRCYY SP GWS+PSDPLELV+TG Y+
Sbjct: 63 EESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYS 122
Query: 129 KPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFP 188
KPTLSALPSP+VTSG++VTL C SR D F+L +E L S+ + Q QA FP
Sbjct: 123 KPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSE-HGAQQHQAEFP 181
Query: 189 VGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCG 244
+ PVT H RC+ S + S PSD LE+ VSG S + T G
Sbjct: 182 MSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAG 237
>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 1 [Homo sapiens]
Length = 591
Score = 241 bits (616), Expect = 3e-64
Identities = 133/216 (61%), Positives = 143/216 (66%), Gaps = 13/216 (6%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TGFY +P
Sbjct: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEP 124
Query: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
TL ALPSPVV SG NVTLQC + F+L EE + KL TL SQ P G QALFPVG
Sbjct: 125 TLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQALFPVG 183
Query: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
PVTPS RW RCY R QVWS PSDLLEI V G
Sbjct: 184 PVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG 219
Score = 123 bits (308), Expect = 2e-28
Identities = 86/250 (34%), Positives = 128/250 (51%), Gaps = 21/250 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G ++ TL A P V++ G +VT++C
Sbjct: 104 AGWSEPSDPLE-------------LVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGL 150
Query: 62 QEYRLVKEGSPEPWDTQNPLEPK--NKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPS 116
+ LV+E P + PK ++A F + +T R+RCYYY +P WS PS
Sbjct: 151 LTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPS 210
Query: 117 DPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQ 176
D LE++V G KP+L VV G ++TLQC S + +D F+L +EG+H L Q
Sbjct: 211 DLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQ 269
Query: 177 LTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTI 236
+G QA F +GPV+ SH RCYG+ ++ WS PSD L+I ++G + + ++
Sbjct: 270 QPQAGLSQANFTLGPVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAGLIPDIPALSV 328
Query: 237 Q-GSQTGCGE 245
Q G + GE
Sbjct: 329 QPGPKVASGE 338
Score = 115 bits (288), Expect = 4e-26
Identities = 85/247 (34%), Positives = 120/247 (48%), Gaps = 21/247 (8%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS+PS L+ +L G K +L GSV++RG S+T++C+ +
Sbjct: 206 WSNPSDLLE-------------ILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDI 252
Query: 64 YRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDP 118
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PSDP
Sbjct: 253 FVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDP 311
Query: 119 LELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177
L++++ G + P LS P P V SGENVTL C S + D F LT+EG L S+
Sbjct: 312 LDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKY 371
Query: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQ 237
S + QA F + PVT + RCY + R + S PS E+ VSG S
Sbjct: 372 -QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTG 430
Query: 238 GSQTGCG 244
+ T G
Sbjct: 431 STPTPAG 437
>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 2 [Homo sapiens]
Length = 590
Score = 241 bits (616), Expect = 3e-64
Identities = 133/216 (61%), Positives = 143/216 (66%), Gaps = 13/216 (6%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TGFY +P
Sbjct: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEP 124
Query: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
TL ALPSPVV SG NVTLQC + F+L EE + KL TL SQ P G QALFPVG
Sbjct: 125 TLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQALFPVG 183
Query: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
PVTPS RW RCY R QVWS PSDLLEI V G
Sbjct: 184 PVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPG 219
Score = 123 bits (308), Expect = 2e-28
Identities = 86/250 (34%), Positives = 128/250 (51%), Gaps = 21/250 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G ++ TL A P V++ G +VT++C
Sbjct: 104 AGWSEPSDPLE-------------LVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGL 150
Query: 62 QEYRLVKEGSPEPWDTQNPLEPK--NKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPS 116
+ LV+E P + PK ++A F + +T R+RCYYY +P WS PS
Sbjct: 151 LTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPS 210
Query: 117 DPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQ 176
D LE++V G KP+L VV G ++TLQC S + +D F+L +EG+H L Q
Sbjct: 211 DLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQ 269
Query: 177 LTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTI 236
+G QA F +GPV+ SH RCYG+ ++ WS PSD L+I ++G + + ++
Sbjct: 270 QPQAGLSQANFTLGPVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAGLIPDIPALSV 328
Query: 237 Q-GSQTGCGE 245
Q G + GE
Sbjct: 329 QPGPKVASGE 338
Score = 115 bits (287), Expect = 5e-26
Identities = 82/229 (35%), Positives = 116/229 (50%), Gaps = 21/229 (9%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS+PS L+ +L G K +L GSV++RG S+T++C+ +
Sbjct: 206 WSNPSDLLE-------------ILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDI 252
Query: 64 YRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDP 118
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PSDP
Sbjct: 253 FVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDP 311
Query: 119 LELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177
L++++ G + P LS P P V SGENVTL C S + D F LT+EG L S+
Sbjct: 312 LDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKY 371
Query: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
S + QA F + PVT + RCY + R + S PS E+ VSG
Sbjct: 372 -QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSG 419
Score = 54.3 bits (129), Expect = 1e-07
Identities = 41/115 (35%), Positives = 56/115 (48%), Gaps = 18/115 (15%)
Query: 37 LWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNK-------ARF 89
L +PG ++ G +VT+ CQ + + L KEG+ P PL K+K A F
Sbjct: 326 LSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHP-----PLCLKSKYQSYRHQAEF 380
Query: 90 SIPSMTEHHAGRYRCYYYS---PAGWSEPSDPLELVVTGFYNKPTLS---ALPSP 138
S+ +T G YRCY P S PS P ELVV+G P+LS + P+P
Sbjct: 381 SMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTP 435
>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 1 [Homo sapiens]
Length = 489
Score = 229 bits (585), Expect = 1e-60
Identities = 123/221 (55%), Positives = 147/221 (66%), Gaps = 13/221 (5%)
Query: 19 VSPALMVLLCL------------GNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P + VL+CL G L K TLWAEPGSVI++G+ VT+ CQG LE QEYRL
Sbjct: 1 MTPIVTVLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS-PAGWSEPSDPLELVVTG 125
+E PW T+ P E K +F IPS+T H GRYRC+Y S AGWSEPSDPLELVVTG
Sbjct: 61 YREKKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSALPSPVVTSG NVTL C S++ F FIL +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+F VGPV+PS RW RCY + VWS PSDLLE+ V G
Sbjct: 181 IFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLG 221
Score = 129 bits (323), Expect = 3e-30
Identities = 89/251 (35%), Positives = 126/251 (50%), Gaps = 22/251 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G K TL A P V++ G +VT+ C +
Sbjct: 105 AGWSEPSDPLE-------------LVVTGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAF 151
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS P
Sbjct: 152 GSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLP 211
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SD LEL+V G KP+LS P P+V GE++TLQC S + +DRF+L +EG+ L
Sbjct: 212 SDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDF-LQLPG 270
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE-EATVFSS 234
+G QA F +GPV+ S+ RC G+ ++ WS PSD L+I ++G+ F S
Sbjct: 271 PQPQAGLSQANFTLGPVSRSYGGQYRCSGA-YNLSSEWSAPSDPLDILIAGQFRGRPFIS 329
Query: 235 TIQGSQTGCGE 245
G GE
Sbjct: 330 VHPGPTVASGE 340
Score = 127 bits (319), Expect = 9e-30
Identities = 79/215 (36%), Positives = 118/215 (54%), Gaps = 8/215 (3%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLE 82
L+ LL LG K +L +PG +++ G S+T++C + + L KEG + P +
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGP-Q 272
Query: 83 PK---NKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALP 136
P+ ++A F++ ++ + G+YRC Y + WS PSDPL++++ G F +P +S P
Sbjct: 273 PQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHP 332
Query: 137 SPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSH 196
P V SGENVTL C S F F+LT+ G L S + ++QA FP+ PVT +H
Sbjct: 333 GPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRS-IHEYPKYQAEFPMSPVTSAH 391
Query: 197 RWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATV 231
RCYGS + S PSD LE+ VSG T+
Sbjct: 392 SGTYRCYGSLSSNPYLLSHPSDSLELMVSGAAETL 426
Score = 52.4 bits (124), Expect = 4e-07
Identities = 37/113 (32%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE-PWD 76
A S L +L+ + + PG ++ G +VT+ CQ + L K G+ + P
Sbjct: 309 APSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTG 125
++ E PK +A F + +T H+G YRCY +P S PSD LEL+V+G
Sbjct: 369 LRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSG 421
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 216 bits (550), Expect = 2e-56
Identities = 120/221 (54%), Positives = 143/221 (64%), Gaps = 13/221 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+F VGPV+PS RW RCY + WS PSDLLE+ V G
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 131 bits (330), Expect = 5e-31
Identities = 80/224 (35%), Positives = 122/224 (54%), Gaps = 6/224 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTY-QSQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQT 241
RCYGS+ + + PSD LE+ VSG S T + T
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTST 436
Score = 130 bits (326), Expect = 1e-30
Identities = 84/248 (33%), Positives = 126/248 (50%), Gaps = 12/248 (4%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFS 233
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G+ S
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAGQFYDRVS 327
Query: 234 STIQGSQT 241
++Q T
Sbjct: 328 LSVQPGPT 335
Score = 69.3 bits (168), Expect = 3e-12
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTSG 143
S P TSG
Sbjct: 428 SPTTGPTSTSG 438
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 216 bits (550), Expect = 2e-56
Identities = 120/221 (54%), Positives = 143/221 (64%), Gaps = 13/221 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+F VGPV+PS RW RCY + WS PSDLLE+ V G
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 134 bits (336), Expect = 1e-31
Identities = 81/227 (35%), Positives = 123/227 (54%), Gaps = 6/227 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQ-SQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCG 244
RCYGS+ + + PSD LE+ VSG S T + T G
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAG 439
Score = 130 bits (326), Expect = 1e-30
Identities = 84/248 (33%), Positives = 126/248 (50%), Gaps = 12/248 (4%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFS 233
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G+ S
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAGQFYDRVS 327
Query: 234 STIQGSQT 241
++Q T
Sbjct: 328 LSVQPGPT 335
Score = 67.0 bits (162), Expect = 1e-11
Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 6/130 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTS 142
S P TS
Sbjct: 428 SPTTGPTSTS 437
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 216 bits (550), Expect = 2e-56
Identities = 120/221 (54%), Positives = 143/221 (64%), Gaps = 13/221 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+F VGPV+PS RW RCY + WS PSDLLE+ V G
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 134 bits (336), Expect = 1e-31
Identities = 81/227 (35%), Positives = 123/227 (54%), Gaps = 6/227 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTYQ-SQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCG 244
RCYGS+ + + PSD LE+ VSG S T + T G
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTSTSAG 439
Score = 130 bits (326), Expect = 1e-30
Identities = 84/248 (33%), Positives = 126/248 (50%), Gaps = 12/248 (4%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFS 233
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G+ S
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAGQFYDRVS 327
Query: 234 STIQGSQT 241
++Q T
Sbjct: 328 LSVQPGPT 335
Score = 67.0 bits (162), Expect = 1e-11
Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 6/130 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTS 142
S P TS
Sbjct: 428 SPTTGPTSTS 437
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 216 bits (550), Expect = 2e-56
Identities = 120/221 (54%), Positives = 143/221 (64%), Gaps = 13/221 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+F VGPV+PS RW RCY + WS PSDLLE+ V G
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLG 221
Score = 131 bits (330), Expect = 5e-31
Identities = 80/224 (35%), Positives = 122/224 (54%), Gaps = 6/224 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTY-QSQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQT 241
RCYGS+ + + PSD LE+ VSG S T + T
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPSSPTTGPTST 436
Score = 130 bits (326), Expect = 1e-30
Identities = 84/248 (33%), Positives = 126/248 (50%), Gaps = 12/248 (4%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFS 233
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G+ S
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAGQFYDRVS 327
Query: 234 STIQGSQT 241
++Q T
Sbjct: 328 LSVQPGPT 335
Score = 69.3 bits (168), Expect = 3e-12
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTSG 143
S P TSG
Sbjct: 428 SPTTGPTSTSG 438
>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform a [Homo sapiens]
Length = 483
Score = 216 bits (549), Expect = 2e-56
Identities = 121/239 (50%), Positives = 146/239 (61%), Gaps = 13/239 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI +G+ VT+RCQG+L+A+EY L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W + EP +F IPS+T HAGRY C YYS SE SDPLELVVTG
Sbjct: 61 YRENKSASW-VRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVVT G NVTLQC S++ FD FIL +EG+ + L+S G A+
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
F VGPV+PS RW RCY + VWS PSDLLE+ V G S G GE
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGE 238
Score = 130 bits (328), Expect = 8e-31
Identities = 81/208 (38%), Positives = 116/208 (55%), Gaps = 8/208 (3%)
Query: 26 LLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLE 82
L+ G SK TL A P V++ G +VT++C + + L KEG P+ ++ +
Sbjct: 114 LVVTGAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHAR 173
Query: 83 PKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPV 139
+ A FS+ ++ YRCY Y SP WS PSD LEL+V G KP+LS P P+
Sbjct: 174 GWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPM 233
Query: 140 VTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWM 199
V GE++TLQC S + +DRF+L +EG+ Q +G QA F +GPV+PSH
Sbjct: 234 VAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQ-PQAGLSQANFTLGPVSPSHGGQ 292
Query: 200 LRCYGSRRHILQVWSEPSDLLEIPVSGE 227
RCY S ++ WS PSD L+I ++G+
Sbjct: 293 YRCY-SAHNLSSEWSAPSDPLDILITGQ 319
Score = 127 bits (320), Expect = 7e-30
Identities = 83/220 (37%), Positives = 122/220 (55%), Gaps = 12/220 (5%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE-----PWDT 77
L+ LL G K +L +PG +++ G S+T++C + + L KEG + W
Sbjct: 212 LLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQP 271
Query: 78 QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSA 134
Q L ++A F++ ++ H G+YRCY + + WS PSDPL++++TG FY++P+LS
Sbjct: 272 QAGL---SQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSV 328
Query: 135 LPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTP 194
P P V G+NVTL C SR +F F+LT+EG L S+ + Q QA F +GPVT
Sbjct: 329 QPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSE-HQAQQNQAEFRMGPVTS 387
Query: 195 SHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSS 234
+H RCY S + S PSD LE+ VS T+ S
Sbjct: 388 AHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPS 427
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT 77
A S L +L+ + +L +P ++ G +VT+ CQ + + L KEG+ P
Sbjct: 307 APSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHP--- 363
Query: 78 QNPLE-------PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVT 124
PL +N+A F + +T H G YRCY +P S PSDPLELVV+
Sbjct: 364 --PLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVS 418
>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform b [Homo sapiens]
Length = 466
Score = 216 bits (549), Expect = 2e-56
Identities = 121/239 (50%), Positives = 146/239 (61%), Gaps = 13/239 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI +G+ VT+RCQG+L+A+EY L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W + EP +F IPS+T HAGRY C YYS SE SDPLELVVTG
Sbjct: 61 YRENKSASW-VRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVVT G NVTLQC S++ FD FIL +EG+ + L+S G A+
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
F VGPV+PS RW RCY + VWS PSDLLE+ V G S G GE
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGE 238
Score = 130 bits (328), Expect = 8e-31
Identities = 81/208 (38%), Positives = 116/208 (55%), Gaps = 8/208 (3%)
Query: 26 LLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLE 82
L+ G SK TL A P V++ G +VT++C + + L KEG P+ ++ +
Sbjct: 114 LVVTGAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHAR 173
Query: 83 PKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPV 139
+ A FS+ ++ YRCY Y SP WS PSD LEL+V G KP+LS P P+
Sbjct: 174 GWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPM 233
Query: 140 VTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWM 199
V GE++TLQC S + +DRF+L +EG+ Q +G QA F +GPV+PSH
Sbjct: 234 VAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQ-PQAGLSQANFTLGPVSPSHGGQ 292
Query: 200 LRCYGSRRHILQVWSEPSDLLEIPVSGE 227
RCY S ++ WS PSD L+I ++G+
Sbjct: 293 YRCY-SAHNLSSEWSAPSDPLDILITGQ 319
Score = 127 bits (318), Expect = 1e-29
Identities = 81/211 (38%), Positives = 119/211 (56%), Gaps = 12/211 (5%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE-----PWDT 77
L+ LL G K +L +PG +++ G S+T++C + + L KEG + W
Sbjct: 212 LLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQP 271
Query: 78 QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSA 134
Q L ++A F++ ++ H G+YRCY + + WS PSDPL++++TG FY++P+LS
Sbjct: 272 QAGL---SQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSV 328
Query: 135 LPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTP 194
P P V G+NVTL C SR +F F+LT+EG L S+ + Q QA F +GPVT
Sbjct: 329 QPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSE-HQAQQNQAEFRMGPVTS 387
Query: 195 SHRWMLRCYGSRRHILQVWSEPSDLLEIPVS 225
+H RCY S + S PSD LE+ VS
Sbjct: 388 AHVGTYRCYSSLSSNPYLLSLPSDPLELVVS 418
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT 77
A S L +L+ + +L +P ++ G +VT+ CQ + + L KEG+ P
Sbjct: 307 APSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHP--- 363
Query: 78 QNPLE-------PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVT 124
PL +N+A F + +T H G YRCY +P S PSDPLELVV+
Sbjct: 364 --PLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVS 418
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 213 bits (543), Expect = 1e-55
Identities = 118/239 (49%), Positives = 145/239 (60%), Gaps = 12/239 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P + VL+CLG + K TLWAEP SVI++G+ VT+ CQG+LEAQEYRL
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W T+ E +F IPS+T H GRY C YYS A WSE SDPL LV+TG
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y KPTLSA PSPVVTSG VTLQC S++ F FIL +EG+ + L+SQ G +A+
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
F VGPV+P+ RW RCYG + VWS PSDLLE+ V G S G GE
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGE 239
Score = 136 bits (342), Expect = 2e-32
Identities = 86/229 (37%), Positives = 127/229 (55%), Gaps = 9/229 (3%)
Query: 24 MVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNP 80
+VL+ G K TL A+P V++ G VT++C+ + + L KEG P+ ++Q
Sbjct: 113 LVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPH 172
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPS 137
++A FS+ ++ + +RCY Y SP WS PSD LEL+V G KP+LS P
Sbjct: 173 ARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPG 232
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
PVV GE++TLQC S + +DRF+L +EG+ L L + +G QA F +GPV+ S+
Sbjct: 233 PVVAPGESLTLQCVSDVGYDRFVLYKEGERDLR-QLPGRQPQAGLSQANFTLGPVSRSYG 291
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGE-EATVFSSTIQGSQTGCGE 245
RCYG+ ++ S PSD L+I ++G+ T F S G GE
Sbjct: 292 GQYRCYGA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGE 339
Score = 118 bits (296), Expect = 4e-27
Identities = 75/209 (35%), Positives = 113/209 (54%), Gaps = 6/209 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE--PWDTQNP 80
L+ LL G K +L +PG V++ G S+T++C + + L KEG + + P
Sbjct: 213 LLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQP 272
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + S PSDPL++++TG P +S P
Sbjct: 273 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPG 332
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S +F F+LT+ G L S + ++QA FP+ PVT +H
Sbjct: 333 PTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRS-IHEYPKYQAEFPMSPVTSAHA 391
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
RCYGS + S PS+ LE+ VSG
Sbjct: 392 GTYRCYGSLNSDPYLLSHPSEPLELVVSG 420
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 213 bits (543), Expect = 1e-55
Identities = 118/239 (49%), Positives = 145/239 (60%), Gaps = 12/239 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P + VL+CLG + K TLWAEP SVI++G+ VT+ CQG+LEAQEYRL
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W T+ E +F IPS+T H GRY C YYS A WSE SDPL LV+TG
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y KPTLSA PSPVVTSG VTLQC S++ F FIL +EG+ + L+SQ G +A+
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
F VGPV+P+ RW RCYG + VWS PSDLLE+ V G S G GE
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGE 239
Score = 136 bits (342), Expect = 2e-32
Identities = 86/229 (37%), Positives = 127/229 (55%), Gaps = 9/229 (3%)
Query: 24 MVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNP 80
+VL+ G K TL A+P V++ G VT++C+ + + L KEG P+ ++Q
Sbjct: 113 LVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPH 172
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPS 137
++A FS+ ++ + +RCY Y SP WS PSD LEL+V G KP+LS P
Sbjct: 173 ARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPG 232
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
PVV GE++TLQC S + +DRF+L +EG+ L L + +G QA F +GPV+ S+
Sbjct: 233 PVVAPGESLTLQCVSDVGYDRFVLYKEGERDLR-QLPGRQPQAGLSQANFTLGPVSRSYG 291
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGE-EATVFSSTIQGSQTGCGE 245
RCYG+ ++ S PSD L+I ++G+ T F S G GE
Sbjct: 292 GQYRCYGA-HNLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGE 339
Score = 118 bits (296), Expect = 4e-27
Identities = 75/209 (35%), Positives = 113/209 (54%), Gaps = 6/209 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE--PWDTQNP 80
L+ LL G K +L +PG V++ G S+T++C + + L KEG + + P
Sbjct: 213 LLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQP 272
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + S PSDPL++++TG P +S P
Sbjct: 273 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPG 332
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S +F F+LT+ G L S + ++QA FP+ PVT +H
Sbjct: 333 PTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRS-IHEYPKYQAEFPMSPVTSAHA 391
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
RCYGS + S PS+ LE+ VSG
Sbjct: 392 GTYRCYGSLNSDPYLLSHPSEPLELVVSG 420
>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
(without TM domain), member 3 [Homo sapiens]
Length = 439
Score = 213 bits (542), Expect = 1e-55
Identities = 122/236 (51%), Positives = 144/236 (61%), Gaps = 13/236 (5%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEPGSVI++G+ VT+RCQG+LE QEY L +E
Sbjct: 5 LTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREK 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS-PAGWSEPSDPLELVVTGFYNK 129
W T+ P E K +F I S+T HAGRY C Y S G SE SDPLELVVTG Y+K
Sbjct: 65 KTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLELVVTGAYSK 124
Query: 130 PTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPV 189
PTLSALPSPVVTSG NVT+QC S++ FD FIL +EG+ + L+S G +A+F V
Sbjct: 125 PTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSV 184
Query: 190 GPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
GPV+PS RW RCYG VWS PSDLL + V G S G GE
Sbjct: 185 GPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGE 240
Score = 122 bits (307), Expect = 2e-28
Identities = 84/232 (36%), Positives = 118/232 (50%), Gaps = 19/232 (8%)
Query: 26 LLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLE 82
L+ G SK TL A P V++ G +VTI+C + + L KEG P+ ++ +
Sbjct: 116 LVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHAR 175
Query: 83 PKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPV 139
++A FS+ ++ YRCY Y +P WS PSD L L+V G KP+LS P PV
Sbjct: 176 GSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPV 235
Query: 140 VTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTP-----SGQFQALFPVGPVTP 194
V GE +T QCGS +DRF+L +E W D P +G QA F +GPV+
Sbjct: 236 VAPGEKLTFQCGSDAGYDRFVLYKE------WGRDFLQRPGRQPQAGLSQANFTLGPVSR 289
Query: 195 SHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE-EATVFSSTIQGSQTGCGE 245
S+ C G+ ++ WS PSD L+I ++G+ A F S G GE
Sbjct: 290 SYGGQYTCSGA-YNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGE 340
Score = 117 bits (292), Expect = 1e-26
Identities = 76/214 (35%), Positives = 112/214 (52%), Gaps = 6/214 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT--QNP 80
L+ LL G K +L +PG V++ G +T +C + L KE + + P
Sbjct: 214 LLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTGFYN-KPTLSALPS 137
++A F++ ++ + G+Y C Y + WS PSDPL++++TG +P LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG L S+ S ++QA FP+ PVT +H
Sbjct: 334 PTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSK-RQSHKYQAEFPMSPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATV 231
RCYGS + + PSD LE+ VSG T+
Sbjct: 393 GTYRCYGSLSSNPYLLTHPSDPLELVVSGAAETL 426
Score = 58.5 bits (140), Expect = 5e-09
Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT 77
A S L +L+ ++ L PG ++ G +VT+ CQ + L KEG+ +
Sbjct: 309 APSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAAD---- 364
Query: 78 QNPLEPKNK-------ARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTG 125
+PL K+K A F + +T HAG YRCY +P + PSDPLELVV+G
Sbjct: 365 -SPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVSG 421
>gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like
receptor, partial [Homo sapiens]
Length = 256
Score = 211 bits (538), Expect = 4e-55
Identities = 123/240 (51%), Positives = 147/240 (61%), Gaps = 14/240 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG L K TLWAEPGSVI++G+ VT+RCQG+LE QEY L
Sbjct: 1 MTPILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS-PAGWSEPSDPLELVVTG 125
+E W T+ P E K +F I S+T HAGRY C Y S AG SE SDPLELVVT
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTA 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y+KPTLSALPSPVVTSG NVT+QC S++ FD FIL +EG+ + L+S G +A
Sbjct: 121 -YSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRA 179
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
+F VGPV+PS RW RCYG VWS PSDLL + V G S G GE
Sbjct: 180 IFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGE 239
Score = 93.6 bits (231), Expect = 1e-19
Identities = 54/135 (40%), Positives = 75/135 (55%), Gaps = 6/135 (4%)
Query: 33 SKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLEPKNKARF 89
SK TL A P V++ G +VTI+C + + L KEG P+ ++ + ++A F
Sbjct: 122 SKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIF 181
Query: 90 SIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 146
S+ ++ YRCY Y +P WS PSD L L+V G KP+LS P PVV GE +
Sbjct: 182 SVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKL 241
Query: 147 TLQCGSRLRFDRFIL 161
T QCGS +DRF+L
Sbjct: 242 TFQCGSDPGYDRFVL 256
>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 3 [Homo sapiens]
Length = 491
Score = 197 bits (502), Expect = 6e-51
Identities = 114/236 (48%), Positives = 142/236 (60%), Gaps = 15/236 (6%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TG KP
Sbjct: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKP 124
Query: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
+L VV G ++TLQC S + +D F+L +EG+H L Q +G QA F +G
Sbjct: 125 SLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQANFTLG 183
Query: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQ-GSQTGCGE 245
PV+ SH RCYG+ ++ WS PSD L+I ++G + + ++Q G + GE
Sbjct: 184 PVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238
Score = 117 bits (292), Expect = 1e-26
Identities = 86/249 (34%), Positives = 120/249 (48%), Gaps = 21/249 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G K +L GSV++RG S+T++C+ +
Sbjct: 104 AGWSEPSDPLE-------------LVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGY 150
Query: 62 QEYRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPS 116
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PS
Sbjct: 151 DIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPS 209
Query: 117 DPLELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
DPL++++ G + P LS P P V SGENVTL C S + D F LT+EG L S
Sbjct: 210 DPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKS 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSST 235
+ S + QA F + PVT + RCY + R + S PS E+ VSG S
Sbjct: 270 KY-QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSP 328
Query: 236 IQGSQTGCG 244
+ T G
Sbjct: 329 TGSTPTPAG 337
>gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
Length = 382
Score = 143 bits (360), Expect = 2e-34
Identities = 95/245 (38%), Positives = 132/245 (53%), Gaps = 22/245 (8%)
Query: 5 SHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEY 64
SHP + P G A S MV++ GN K +L A PG ++ G V ++C + + +
Sbjct: 98 SHPHS---PTGWSAPSNP-MVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHF 153
Query: 65 RLVKEGSPEPWDTQNPL-------EPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSE 114
L KE W +++P + +KA FSI SM AG YRCY ++P S
Sbjct: 154 FLHKE-----WISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSA 208
Query: 115 PSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLD 174
PSDPL++VVTG Y KP+LSA P P V +GE+VTL C SR +D + L+ EG L
Sbjct: 209 PSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAH-ERRLP 267
Query: 175 SQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSS 234
+ + FQA FP+GP T H RC+GS RH WS+PSD L + V+G ++ + S
Sbjct: 268 AVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPS 325
Query: 235 TIQGS 239
+ S
Sbjct: 326 PTEPS 330
Score = 111 bits (277), Expect = 7e-25
Identities = 77/220 (35%), Positives = 107/220 (48%), Gaps = 7/220 (3%)
Query: 29 LGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKAR 88
+G K L A P +V+ RG VT+RC + L KE + +
Sbjct: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEG--- 79
Query: 89 FSIPSMTEHHAGRYRC---YYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGEN 145
F++ +T HAG Y C + +SP GWS PS+P+ ++VTG + KP+L A P P+V SGE
Sbjct: 80 FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGER 139
Query: 146 VTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGS 205
V LQC S + F+ F L +E K L Q+ G +A F +G + + RCYGS
Sbjct: 140 VILQCWSDIMFEHFFLHKEWISKDPSRLVGQIH-DGVSKANFSIGSMMRALAGTYRCYGS 198
Query: 206 RRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
H S PSD L+I V+G S G + GE
Sbjct: 199 VTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQAGE 238
>gi|224586788 natural cytotoxicity triggering receptor 1 isoform c
[Homo sapiens]
Length = 287
Score = 140 bits (354), Expect = 8e-34
Identities = 88/221 (39%), Positives = 113/221 (51%), Gaps = 20/221 (9%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
+S L LLC+G L K +WAEP ++ + VTI CQG A EY+L
Sbjct: 1 MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
EGS D P E NK +F IP M AG+Y C Y WSEPS+ L+LVVT
Sbjct: 61 HFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEM 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+ PTLS P P V SGE VT C F+L +EG G+ QA
Sbjct: 121 YDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEG------RSSHVQRGYGKVQAE 174
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE 227
FP+GPVT +HR RC+GS + WS PS+ +++ V+G+
Sbjct: 175 FPLGPVTTAHRGTYRCFGSYNN--HAWSFPSEPVKLLVTGD 213
Score = 50.4 bits (119), Expect = 1e-06
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 36 TLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMT 95
TL PG + G VT C+ + L+KEG K +A F + +T
Sbjct: 125 TLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEGRSSHVQRGYG---KVQAEFPLGPVT 181
Query: 96 EHHAGRYRCY-YYSPAGWSEPSDPLELVVTGFYNKPTLS 133
H G YRC+ Y+ WS PS+P++L+VTG +L+
Sbjct: 182 TAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLA 220
>gi|224586786 natural cytotoxicity triggering receptor 1 isoform b
[Homo sapiens]
Length = 303
Score = 140 bits (354), Expect = 8e-34
Identities = 88/221 (39%), Positives = 113/221 (51%), Gaps = 20/221 (9%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
+S L LLC+G L K +WAEP ++ + VTI CQG A EY+L
Sbjct: 1 MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
EGS D P E NK +F IP M AG+Y C Y WSEPS+ L+LVVT
Sbjct: 61 HFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEM 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+ PTLS P P V SGE VT C F+L +EG G+ QA
Sbjct: 121 YDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEG------RSSHVQRGYGKVQAE 174
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE 227
FP+GPVT +HR RC+GS + WS PS+ +++ V+G+
Sbjct: 175 FPLGPVTTAHRGTYRCFGSYNN--HAWSFPSEPVKLLVTGD 213
Score = 50.4 bits (119), Expect = 1e-06
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 36 TLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMT 95
TL PG + G VT C+ + L+KEG K +A F + +T
Sbjct: 125 TLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEGRSSHVQRGYG---KVQAEFPLGPVT 181
Query: 96 EHHAGRYRCY-YYSPAGWSEPSDPLELVVTGFYNKPTLS 133
H G YRC+ Y+ WS PS+P++L+VTG +L+
Sbjct: 182 TAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLA 220
>gi|4758692 natural cytotoxicity triggering receptor 1 isoform a
[Homo sapiens]
Length = 304
Score = 140 bits (354), Expect = 8e-34
Identities = 88/221 (39%), Positives = 113/221 (51%), Gaps = 20/221 (9%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
+S L LLC+G L K +WAEP ++ + VTI CQG A EY+L
Sbjct: 1 MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
EGS D P E NK +F IP M AG+Y C Y WSEPS+ L+LVVT
Sbjct: 61 HFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEM 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+ PTLS P P V SGE VT C F+L +EG G+ QA
Sbjct: 121 YDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEG------RSSHVQRGYGKVQAE 174
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGE 227
FP+GPVT +HR RC+GS + WS PS+ +++ V+G+
Sbjct: 175 FPLGPVTTAHRGTYRCFGSYNN--HAWSFPSEPVKLLVTGD 213
Score = 50.4 bits (119), Expect = 1e-06
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Query: 36 TLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMT 95
TL PG + G VT C+ + L+KEG K +A F + +T
Sbjct: 125 TLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEGRSSHVQRGYG---KVQAEFPLGPVT 181
Query: 96 EHHAGRYRCY-YYSPAGWSEPSDPLELVVTGFYNKPTLS 133
H G YRC+ Y+ WS PS+P++L+VTG +L+
Sbjct: 182 TAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLA 220
>gi|134268644 killer cell immunoglobulin-like receptor, three
domains, long cytoplasmic tail, 1 precursor [Homo
sapiens]
Length = 444
Score = 139 bits (349), Expect = 3e-33
Identities = 93/240 (38%), Positives = 132/240 (55%), Gaps = 12/240 (5%)
Query: 5 SHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEY 64
SHP + P G A S +++++ GN K +L A PG ++ G V ++C + + +
Sbjct: 98 SHPHS---PTGWSAPSNPVVIMVT-GNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHF 153
Query: 65 RLVKEG-SPEPWDTQNPL-EPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPL 119
L KEG S +P + + +KA FSI M AG YRCY ++P S PSDPL
Sbjct: 154 FLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPL 213
Query: 120 ELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTP 179
++VVTG Y KP+LSA P P V +GE+VTL C SR +D + L+ EG L +
Sbjct: 214 DIVVTGPYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAH-ERRLPAVRKV 272
Query: 180 SGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGS 239
+ FQA FP+GP T H RC+GS RH WS+PSD L + V+G ++ + S + S
Sbjct: 273 NRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPSPTEPS 330
Score = 117 bits (293), Expect = 1e-26
Identities = 79/220 (35%), Positives = 110/220 (50%), Gaps = 7/220 (3%)
Query: 29 LGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKAR 88
+G K L A P +V+ RG VT+RC + L KE + ++
Sbjct: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIFHGRIFQES--- 79
Query: 89 FSIPSMTEHHAGRYRC---YYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGEN 145
F++ +T HAG Y C + +SP GWS PS+P+ ++VTG + KP+L A P P+V SGE
Sbjct: 80 FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGER 139
Query: 146 VTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGS 205
V LQC S + F+ F L +EG K L Q+ G +A F +GP+ + RCYGS
Sbjct: 140 VILQCWSDIMFEHFFLHKEGISKDPSRLVGQI-HDGVSKANFSIGPMMLALAGTYRCYGS 198
Query: 206 RRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245
H S PSD L+I V+G S G + GE
Sbjct: 199 VTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQAGE 238
>gi|143770741 glycoprotein VI (platelet) isoform 1 [Homo sapiens]
Length = 620
Score = 138 bits (347), Expect = 5e-33
Identities = 89/223 (39%), Positives = 113/223 (50%), Gaps = 26/223 (11%)
Query: 19 VSPALMVLLCLG-----------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLV 67
+SP+ L CLG L K +L A P S++ VT+RCQG YRL
Sbjct: 1 MSPSPTALFCLGLCLGRVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLE 60
Query: 68 KEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFY 127
K S D +A IP+M AGRYRC Y + + WS PSD LELV TG +
Sbjct: 61 KLSSSRYQD---------QAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVF 111
Query: 128 NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALF 187
KP+LSA P P V+SG +VTLQC +R FD+F L +EGD P ++A F
Sbjct: 112 AKPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPA------PYKNPERWYRASF 165
Query: 188 PVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEAT 230
P+ VT +H RCY +WS PSD LE+ V+G T
Sbjct: 166 PIITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTGTSVT 208
Score = 32.0 bits (71), Expect = 0.53
Identities = 35/114 (30%), Positives = 49/114 (42%), Gaps = 19/114 (16%)
Query: 129 KPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFP 188
KP+L ALPS +V + VTL+C D + L KLS + Q QA+
Sbjct: 27 KPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRL-----EKLS-------SSRYQDQAVLF 74
Query: 189 VGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTG 242
+ + S RC + WS PSD LE+ +G VF+ +Q G
Sbjct: 75 IPAMKRSLAGRYRCSYQNGSL---WSLPSDQLELVATG----VFAKPSLSAQPG 121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.423
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,658,553
Number of Sequences: 37866
Number of extensions: 590374
Number of successful extensions: 2266
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 50
Number of HSP's that attempted gapping in prelim test: 1409
Number of HSP's gapped (non-prelim): 406
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.