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Search of human proteins with 32895363
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32895363 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 2 [Homo sapiens]
(287 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32895363 leukocyte immunoglobulin-like receptor subfamily A m... 593 e-170
gi|32490553 leukocyte immunoglobulin-like receptor subfamily A m... 584 e-167
gi|32895365 leukocyte immunoglobulin-like receptor subfamily A m... 474 e-134
gi|32895361 leukocyte immunoglobulin-like receptor subfamily A m... 466 e-131
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A... 298 3e-81
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B... 289 2e-78
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B... 289 2e-78
gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B... 249 2e-66
gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B... 249 2e-66
gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m... 246 2e-65
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B... 242 3e-64
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ... 242 3e-64
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (... 230 9e-61
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B... 217 1e-56
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B... 217 1e-56
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B... 217 1e-56
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B... 217 1e-56
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A... 215 3e-56
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (... 215 3e-56
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B... 214 9e-56
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B... 214 9e-56
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ... 213 1e-55
gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like... 212 3e-55
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B... 196 2e-50
gi|224586788 natural cytotoxicity triggering receptor 1 isoform ... 168 4e-42
gi|4758692 natural cytotoxicity triggering receptor 1 isoform a ... 163 1e-40
gi|224586786 natural cytotoxicity triggering receptor 1 isoform ... 163 2e-40
gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens] 152 3e-37
gi|134133244 killer cell immunoglobulin-like receptor, three dom... 149 3e-36
gi|124107606 killer cell immunoglobulin-like receptor, two domai... 147 1e-35
>gi|32895363 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 2 [Homo sapiens]
Length = 287
Score = 593 bits (1528), Expect = e-170
Identities = 287/287 (100%), Positives = 287/287 (100%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
Query: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE
Sbjct: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
Query: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS
Sbjct: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
Query: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDS 240
GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDS
Sbjct: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDS 240
Query: 241 GTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
GTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR
Sbjct: 241 GTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
>gi|32490553 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 1 [Homo sapiens]
Length = 299
Score = 584 bits (1505), Expect = e-167
Identities = 287/299 (95%), Positives = 287/299 (95%), Gaps = 12/299 (4%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLG------------NLSKATLWAEPGSVISRG 48
MAPWSHPSAQLQPVGGDAVSPALMVLLCLG NLSKATLWAEPGSVISRG
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRG 60
Query: 49 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 108
NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS
Sbjct: 61 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 120
Query: 109 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 168
PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK
Sbjct: 121 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 180
Query: 169 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 228
LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA
Sbjct: 181 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 240
Query: 229 DNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
DNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR
Sbjct: 241 DNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 299
>gi|32895365 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 4 [Homo sapiens]
Length = 253
Score = 474 bits (1221), Expect = e-134
Identities = 226/226 (100%), Positives = 226/226 (100%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLE 60
Query: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE
Sbjct: 61 AQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLE 120
Query: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS
Sbjct: 121 LVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPS 180
Query: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG
Sbjct: 181 GQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
>gi|32895361 leukocyte immunoglobulin-like receptor subfamily A
member 5 isoform 3 [Homo sapiens]
Length = 265
Score = 466 bits (1198), Expect = e-131
Identities = 226/238 (94%), Positives = 226/238 (94%), Gaps = 12/238 (5%)
Query: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLG------------NLSKATLWAEPGSVISRG 48
MAPWSHPSAQLQPVGGDAVSPALMVLLCLG NLSKATLWAEPGSVISRG
Sbjct: 1 MAPWSHPSAQLQPVGGDAVSPALMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRG 60
Query: 49 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 108
NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS
Sbjct: 61 NSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS 120
Query: 109 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 168
PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK
Sbjct: 121 PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHK 180
Query: 169 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG
Sbjct: 181 LSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 238
>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
member 6 [Homo sapiens]
Length = 481
Score = 298 bits (764), Expect = 3e-81
Identities = 150/222 (67%), Positives = 169/222 (76%), Gaps = 12/222 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++PAL LLCLG K TLWAEPGSVIS G+ VTI CQG+LEAQEY+L
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
KEGSPEP D NPLEPKNKARFSIPSMT+HHAGRYRC+YYS AGWSEPSDPLELV+TGF
Sbjct: 61 DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
YNKPTLSALPSPVV SG N+TL+CGS+ + F+L +EG+H+L TLDSQ SG FQAL
Sbjct: 121 YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 228
FPVGPVTPSHRW CY + +VWS PSD LEI SG +
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVS 222
Score = 192 bits (488), Expect = 3e-49
Identities = 121/289 (41%), Positives = 163/289 (56%), Gaps = 19/289 (6%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WSHPS L+ +L G K +L G V++ G S+T++C +
Sbjct: 207 WSHPSDPLE-------------ILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDR 253
Query: 64 YRLVKEGSPEPWDT--QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPL 119
+ L KEG + Q P ++A F++ ++ H G+YRCY + + WS PSDPL
Sbjct: 254 FVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAHNLSSEWSAPSDPL 313
Query: 120 ELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLT 178
+++ G Y+ +LSA P P V SGENVTL C SR FD F+LT+EG L S +
Sbjct: 314 NILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEGAAHPPLRLRS-MY 372
Query: 179 PSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKS 238
+ ++QA FP+ PVT +H RCYGS + S PS+ LE+ VSG + S
Sbjct: 373 GAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSGHSGGSSLPPTGP 432
Query: 239 DSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
S ASH +DY VENLIRMGMAGL+LV LGIL+F+ HSQR+PQ AAGR
Sbjct: 433 PSTPASHAKDYTVENLIRMGMAGLVLVFLGILLFEAQHSQRNPQDAAGR 481
Score = 142 bits (357), Expect = 4e-34
Identities = 86/231 (37%), Positives = 123/231 (53%), Gaps = 21/231 (9%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G +K TL A P V++ G ++T+RC
Sbjct: 104 AGWSEPSDPLE-------------LVMTGFYNKPTLSALPSPVVASGGNMTLRCGSQKGY 150
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L+KEG P D+Q +A F + +T H R+ CYYY +P WS P
Sbjct: 151 HHFVLMKEGEHQLPRTLDSQQLHSGGFQALFPVGPVTPSHRWRFTCYYYYTNTPRVWSHP 210
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPLE++ +G KP+L L PV+ G+++TLQCGS + +DRF+L +EG+
Sbjct: 211 SDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYDRFVLYKEGERDF-LQRPG 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
Q +G QA F +GPV+PSH RCYG+ ++ WS PSD L I ++G
Sbjct: 270 QQPQAGLSQANFTLGPVSPSHGGQYRCYGA-HNLSSEWSAPSDPLNILMAG 319
>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 1 [Homo sapiens]
Length = 632
Score = 289 bits (739), Expect = 2e-78
Identities = 147/222 (66%), Positives = 165/222 (74%), Gaps = 12/222 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++PAL LLCLG K TLWAEPGSVIS G+ VTI CQG+ EAQEYRL
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
KEGSPEP D NPLEPKNKARFSIPSMTEHHAGRYRC+YYS AGWSEPSDPLE+V+TG
Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVV SG N+TL+CGS+ + F+L +EG+H+L TLDSQ S FQAL
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 228
FPVGPVTPSHRW CY + VWS PSD LEI SG +
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVS 222
Score = 137 bits (345), Expect = 1e-32
Identities = 84/231 (36%), Positives = 123/231 (53%), Gaps = 21/231 (9%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ ++ G SK TL A P V++ G ++T+RC
Sbjct: 104 AGWSEPSDPLE-------------MVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGY 150
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L+KEG P D+Q +A F + +T H R+ CYYY +P WS P
Sbjct: 151 HHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHP 210
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPLE++ +G KP+L L PV+ G+++TLQCGS + ++RF+L +EG+
Sbjct: 211 SDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDF-LQRPG 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
Q +G QA F +GPV+PS+ RCYG+ ++ WS PSD L I ++G
Sbjct: 270 QQPQAGLSQANFTLGPVSPSNGGQYRCYGA-HNLSSEWSAPSDPLNILMAG 319
Score = 132 bits (331), Expect = 5e-31
Identities = 94/283 (33%), Positives = 145/283 (51%), Gaps = 28/283 (9%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WSHPS L+ +L G K +L G V++ G S+T++C +
Sbjct: 207 WSHPSDPLE-------------ILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNR 253
Query: 64 YRLVKEGSPEPWDT--QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPL 119
+ L KEG + Q P ++A F++ ++ + G+YRCY + + WS PSDPL
Sbjct: 254 FVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPL 313
Query: 120 ELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLT 178
+++ G Y+ +LSA P P V SGENVTL C S +FD F+LT+EG L S +
Sbjct: 314 NILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRS-MY 372
Query: 179 PSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG--AADNLSPSQN 236
+ ++QA FP+ PVT +H RCYGS + S PS+ LE+ VSG +L P+
Sbjct: 373 GAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGP 432
Query: 237 KSDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQR 279
S G +L+ + +G++ +++L +L+F QR
Sbjct: 433 PSTPGLGRYLE-------VLIGVSVAFVLLLFLLLFLLLRRQR 468
>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
member 3 isoform 2 [Homo sapiens]
Length = 631
Score = 289 bits (739), Expect = 2e-78
Identities = 147/222 (66%), Positives = 165/222 (74%), Gaps = 12/222 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++PAL LLCLG K TLWAEPGSVIS G+ VTI CQG+ EAQEYRL
Sbjct: 1 MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
KEGSPEP D NPLEPKNKARFSIPSMTEHHAGRYRC+YYS AGWSEPSDPLE+V+TG
Sbjct: 61 HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVV SG N+TL+CGS+ + F+L +EG+H+L TLDSQ S FQAL
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 228
FPVGPVTPSHRW CY + VWS PSD LEI SG +
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVS 222
Score = 137 bits (345), Expect = 1e-32
Identities = 84/231 (36%), Positives = 123/231 (53%), Gaps = 21/231 (9%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ ++ G SK TL A P V++ G ++T+RC
Sbjct: 104 AGWSEPSDPLE-------------MVMTGAYSKPTLSALPSPVVASGGNMTLRCGSQKGY 150
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L+KEG P D+Q +A F + +T H R+ CYYY +P WS P
Sbjct: 151 HHFVLMKEGEHQLPRTLDSQQLHSRGFQALFPVGPVTPSHRWRFTCYYYYTNTPWVWSHP 210
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPLE++ +G KP+L L PV+ G+++TLQCGS + ++RF+L +EG+
Sbjct: 211 SDPLEILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNRFVLYKEGERDF-LQRPG 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
Q +G QA F +GPV+PS+ RCYG+ ++ WS PSD L I ++G
Sbjct: 270 QQPQAGLSQANFTLGPVSPSNGGQYRCYGA-HNLSSEWSAPSDPLNILMAG 319
Score = 132 bits (331), Expect = 5e-31
Identities = 94/283 (33%), Positives = 145/283 (51%), Gaps = 28/283 (9%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WSHPS L+ +L G K +L G V++ G S+T++C +
Sbjct: 207 WSHPSDPLE-------------ILPSGVSRKPSLLTLQGPVLAPGQSLTLQCGSDVGYNR 253
Query: 64 YRLVKEGSPEPWDT--QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPL 119
+ L KEG + Q P ++A F++ ++ + G+YRCY + + WS PSDPL
Sbjct: 254 FVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAHNLSSEWSAPSDPL 313
Query: 120 ELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLT 178
+++ G Y+ +LSA P P V SGENVTL C S +FD F+LT+EG L S +
Sbjct: 314 NILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEGAAHPPLRLRS-MY 372
Query: 179 PSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG--AADNLSPSQN 236
+ ++QA FP+ PVT +H RCYGS + S PS+ LE+ VSG +L P+
Sbjct: 373 GAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSGHSGGSSLPPTGP 432
Query: 237 KSDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQR 279
S G +L+ + +G++ +++L +L+F QR
Sbjct: 433 PSTPGLGRYLE-------VLIGVSVAFVLLLFLLLFLLLRRQR 468
>gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 2 [Homo sapiens]
Length = 447
Score = 249 bits (636), Expect = 2e-66
Identities = 138/235 (58%), Positives = 158/235 (67%), Gaps = 13/235 (5%)
Query: 21 PALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVK 68
P LLCLG L K TLWAEPGSVIS GNSVTI CQGTLEA+EYRL K
Sbjct: 3 PTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDK 62
Query: 69 EGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYN 128
E SP PWD QNPLEPKNKARFSIPSMTE +AGRYRCYY SP GWS+PSDPLELV+TG Y+
Sbjct: 63 EESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYS 122
Query: 129 KPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFP 188
KPTLSALPSP+VTSG++VTL C SR D F+L +E L S+ + Q QA FP
Sbjct: 123 KPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSE-HGAQQHQAEFP 181
Query: 189 VGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTA 243
+ PVT H RC+ S + S PSD LE+ VSG+ ++ PS +S S A
Sbjct: 182 MSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAA 236
Score = 63.2 bits (152), Expect = 3e-10
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 20/146 (13%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS PS L+ L+ G SK TL A P +++ G SVT+ CQ
Sbjct: 106 WSQPSDPLE-------------LVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDT 152
Query: 64 YRLVKEGSPEPW---DTQNPLEPKNKARFSIPSMTEHHAGRYRCYY---YSPAGWSEPSD 117
+ L+KE + P +++ + +++A F + +T H G YRC+ +S S PSD
Sbjct: 153 FLLIKERAAHPLLHLRSEHGAQ-QHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSD 211
Query: 118 PLELVVTGFYNKPTLSALPSPVVTSG 143
PLEL+V+G P S S +G
Sbjct: 212 PLELIVSGSLEDPRPSPTRSVSTAAG 237
>gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B,
member 4 isoform 1 [Homo sapiens]
Length = 448
Score = 249 bits (636), Expect = 2e-66
Identities = 138/235 (58%), Positives = 158/235 (67%), Gaps = 13/235 (5%)
Query: 21 PALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVK 68
P LLCLG L K TLWAEPGSVIS GNSVTI CQGTLEA+EYRL K
Sbjct: 3 PTFTALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDK 62
Query: 69 EGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYN 128
E SP PWD QNPLEPKNKARFSIPSMTE +AGRYRCYY SP GWS+PSDPLELV+TG Y+
Sbjct: 63 EESPAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYS 122
Query: 129 KPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFP 188
KPTLSALPSP+VTSG++VTL C SR D F+L +E L S+ + Q QA FP
Sbjct: 123 KPTLSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSE-HGAQQHQAEFP 181
Query: 189 VGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTA 243
+ PVT H RC+ S + S PSD LE+ VSG+ ++ PS +S S A
Sbjct: 182 MSPVTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAA 236
Score = 63.2 bits (152), Expect = 3e-10
Identities = 46/146 (31%), Positives = 69/146 (47%), Gaps = 20/146 (13%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS PS L+ L+ G SK TL A P +++ G SVT+ CQ
Sbjct: 106 WSQPSDPLE-------------LVMTGAYSKPTLSALPSPLVTSGKSVTLLCQSRSPMDT 152
Query: 64 YRLVKEGSPEPW---DTQNPLEPKNKARFSIPSMTEHHAGRYRCYY---YSPAGWSEPSD 117
+ L+KE + P +++ + +++A F + +T H G YRC+ +S S PSD
Sbjct: 153 FLLIKERAAHPLLHLRSEHGAQ-QHQAEFPMSPVTSVHGGTYRCFSSHGFSHYLLSHPSD 211
Query: 118 PLELVVTGFYNKPTLSALPSPVVTSG 143
PLEL+V+G P S S +G
Sbjct: 212 PLELIVSGSLEDPRPSPTRSVSTAAG 237
>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
member 4 [Homo sapiens]
Length = 499
Score = 246 bits (627), Expect = 2e-65
Identities = 127/198 (64%), Positives = 144/198 (72%), Gaps = 1/198 (0%)
Query: 31 NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFS 90
NL K LWAEPG VI+ N VTI CQGTLEAQ YRL KEG+ LE +NK + S
Sbjct: 25 NLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLS 84
Query: 91 IPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQC 150
IPSM HAGRY CYY SPAGWSEPSDPLELVVT Y++PTLSALPSPVVTSG NVTL+C
Sbjct: 85 IPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTLRC 143
Query: 151 GSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHIL 210
SRL RF L EEGDH+LSWTL+S G+FQALFP+GP+T S+R RCYG +
Sbjct: 144 ASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTP 203
Query: 211 QVWSEPSDLLEIPVSGAA 228
VWSEPSD L++ VSG +
Sbjct: 204 YVWSEPSDPLQLLVSGVS 221
Score = 197 bits (500), Expect = 1e-50
Identities = 121/284 (42%), Positives = 167/284 (58%), Gaps = 21/284 (7%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS PS LQ LL G K +L G V++ G ++T++C +
Sbjct: 206 WSEPSDPLQ-------------LLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIR 252
Query: 64 YRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDP 118
Y L KEG+ P+ Q P ++A F++ ++ + G+YRCY + + WS PSDP
Sbjct: 253 YTLYKEGADGLPQRPGRQ-PQAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDP 311
Query: 119 LELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177
L++++ G ++P+LS P P VTSGE VTL C S F+LT+EG L S +
Sbjct: 312 LDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRS-M 370
Query: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNK 237
+ ++QA FP+ PVT +H RCYGSR + S PS+ LE+ VSGA + L+P+Q K
Sbjct: 371 YGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKK 430
Query: 238 SDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSP 281
SDS TA HLQDY VENLIRMG+AGL+L+ LGIL+F+ HSQRSP
Sbjct: 431 SDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRSP 474
Score = 130 bits (326), Expect = 2e-30
Identities = 87/231 (37%), Positives = 123/231 (53%), Gaps = 22/231 (9%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L + S+ TL A P V++ G +VT+RC L
Sbjct: 104 AGWSEPSDPLE--------------LVVTAYSRPTLSALPSPVVTSGVNVTLRCASRLGL 149
Query: 62 QEYRLVKEGSPEPWDTQNPLEP---KNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L++EG T N + K +A F + +T + G +RCY Y +P WSEP
Sbjct: 150 GRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEP 209
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SDPL+L+V+G KP+L L PVVT GEN+TLQCGS + + R+ L +EG L
Sbjct: 210 SDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGR 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
Q +G QA F + PV+ S+ RCYG+ ++ WS PSD L+I ++G
Sbjct: 270 Q-PQAGLSQANFTLSPVSRSYGGQYRCYGA-HNVSSEWSAPSDPLDILIAG 318
>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 1 [Homo sapiens]
Length = 591
Score = 242 bits (617), Expect = 3e-64
Identities = 133/218 (61%), Positives = 144/218 (66%), Gaps = 13/218 (5%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TGFY +P
Sbjct: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEP 124
Query: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
TL ALPSPVV SG NVTLQC + F+L EE + KL TL SQ P G QALFPVG
Sbjct: 125 TLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQALFPVG 183
Query: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 228
PVTPS RW RCY R QVWS PSDLLEI V G +
Sbjct: 184 PVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVS 221
Score = 122 bits (305), Expect = 5e-28
Identities = 82/230 (35%), Positives = 119/230 (51%), Gaps = 20/230 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G ++ TL A P V++ G +VT++C
Sbjct: 104 AGWSEPSDPLE-------------LVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGL 150
Query: 62 QEYRLVKEGSPEPWDTQNPLEPK--NKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPS 116
+ LV+E P + PK ++A F + +T R+RCYYY +P WS PS
Sbjct: 151 LTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPS 210
Query: 117 DPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQ 176
D LE++V G KP+L VV G ++TLQC S + +D F+L +EG+H L Q
Sbjct: 211 DLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQ 269
Query: 177 LTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+G QA F +GPV+ SH RCYG+ ++ WS PSD L+I ++G
Sbjct: 270 QPQAGLSQANFTLGPVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAG 318
Score = 116 bits (290), Expect = 3e-26
Identities = 85/239 (35%), Positives = 122/239 (51%), Gaps = 23/239 (9%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS+PS L+ +L G K +L GSV++RG S+T++C+ +
Sbjct: 206 WSNPSDLLE-------------ILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDI 252
Query: 64 YRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDP 118
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PSDP
Sbjct: 253 FVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDP 311
Query: 119 LELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177
L++++ G + P LS P P V SGENVTL C S + D F LT+EG L S+
Sbjct: 312 LDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKY 371
Query: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA--DNLSPS 234
S + QA F + PVT + RCY + R + S PS E+ VSG + +LSP+
Sbjct: 372 -QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPT 429
Score = 55.1 bits (131), Expect = 7e-08
Identities = 41/117 (35%), Positives = 55/117 (47%), Gaps = 15/117 (12%)
Query: 37 LWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNK-------ARF 89
L +PG ++ G +VT+ CQ + + L KEG+ P PL K+K A F
Sbjct: 326 LSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHP-----PLCLKSKYQSYRHQAEF 380
Query: 90 SIPSMTEHHAGRYRCYYYS---PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSG 143
S+ +T G YRCY P S PS P ELVV+G P+LS S +G
Sbjct: 381 SMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAG 437
>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 2 [Homo sapiens]
Length = 590
Score = 242 bits (617), Expect = 3e-64
Identities = 133/218 (61%), Positives = 144/218 (66%), Gaps = 13/218 (5%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TGFY +P
Sbjct: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGFYAEP 124
Query: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
TL ALPSPVV SG NVTLQC + F+L EE + KL TL SQ P G QALFPVG
Sbjct: 125 TLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQALFPVG 183
Query: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 228
PVTPS RW RCY R QVWS PSDLLEI V G +
Sbjct: 184 PVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVS 221
Score = 122 bits (305), Expect = 5e-28
Identities = 82/230 (35%), Positives = 119/230 (51%), Gaps = 20/230 (8%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G ++ TL A P V++ G +VT++C
Sbjct: 104 AGWSEPSDPLE-------------LVATGFYAEPTLLALPSPVVASGGNVTLQCDTLDGL 150
Query: 62 QEYRLVKEGSPEPWDTQNPLEPK--NKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPS 116
+ LV+E P + PK ++A F + +T R+RCYYY +P WS PS
Sbjct: 151 LTFVLVEEEQKLPRTLYSQKLPKGPSQALFPVGPVTPSCRWRFRCYYYYRKNPQVWSNPS 210
Query: 117 DPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQ 176
D LE++V G KP+L VV G ++TLQC S + +D F+L +EG+H L Q
Sbjct: 211 DLLEILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQ 269
Query: 177 LTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+G QA F +GPV+ SH RCYG+ ++ WS PSD L+I ++G
Sbjct: 270 QPQAGLSQANFTLGPVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAG 318
Score = 116 bits (291), Expect = 2e-26
Identities = 86/246 (34%), Positives = 124/246 (50%), Gaps = 23/246 (9%)
Query: 4 WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63
WS+PS L+ +L G K +L GSV++RG S+T++C+ +
Sbjct: 206 WSNPSDLLE-------------ILVPGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGYDI 252
Query: 64 YRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDP 118
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PSDP
Sbjct: 253 FVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDP 311
Query: 119 LELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177
L++++ G + P LS P P V SGENVTL C S + D F LT+EG L S+
Sbjct: 312 LDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKY 371
Query: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA--DNLSPSQ 235
S + QA F + PVT + RCY + R + S PS E+ VSG + +LSP+
Sbjct: 372 -QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTG 430
Query: 236 NKSDSG 241
+ G
Sbjct: 431 STPTPG 436
>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 1 [Homo sapiens]
Length = 489
Score = 230 bits (587), Expect = 9e-61
Identities = 125/229 (54%), Positives = 150/229 (65%), Gaps = 13/229 (5%)
Query: 19 VSPALMVLLCL------------GNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P + VL+CL G L K TLWAEPGSVI++G+ VT+ CQG LE QEYRL
Sbjct: 1 MTPIVTVLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS-PAGWSEPSDPLELVVTG 125
+E PW T+ P E K +F IPS+T H GRYRC+Y S AGWSEPSDPLELVVTG
Sbjct: 61 YREKKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSALPSPVVTSG NVTL C S++ F FIL +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
+F VGPV+PS RW RCY + VWS PSDLLE+ V G + S S
Sbjct: 181 IFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLS 229
Score = 196 bits (499), Expect = 2e-50
Identities = 120/277 (43%), Positives = 163/277 (58%), Gaps = 21/277 (7%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLE 82
L+ LL LG K +L +PG +++ G S+T++C + + L KEG + P +
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDFLQLPGP-Q 272
Query: 83 PK---NKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALP 136
P+ ++A F++ ++ + G+YRC Y + WS PSDPL++++ G F +P +S P
Sbjct: 273 PQAGLSQANFTLGPVSRSYGGQYRCSGAYNLSSEWSAPSDPLDILIAGQFRGRPFISVHP 332
Query: 137 SPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSH 196
P V SGENVTL C S F F+LT+ G L S + ++QA FP+ PVT +H
Sbjct: 333 GPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLRLRS-IHEYPKYQAEFPMSPVTSAH 391
Query: 197 RWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDS-------------GTA 243
RCYGS + S PSD LE+ VSGAA+ LSP QNKSDS TA
Sbjct: 392 SGTYRCYGSLSSNPYLLSHPSDSLELMVSGAAETLSPPQNKSDSKAGAANTLSPSQNKTA 451
Query: 244 SHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRS 280
SH QDY VENLIRMG+AGL+LVVLGIL+F+ HSQRS
Sbjct: 452 SHPQDYTVENLIRMGIAGLVLVVLGILLFEAQHSQRS 488
Score = 127 bits (318), Expect = 1e-29
Identities = 84/231 (36%), Positives = 120/231 (51%), Gaps = 21/231 (9%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G K TL A P V++ G +VT+ C +
Sbjct: 105 AGWSEPSDPLE-------------LVVTGAYIKPTLSALPSPVVTSGGNVTLHCVSQVAF 151
Query: 62 QEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS P
Sbjct: 152 GSFILCKEGEDEHPQCLNSQPRTHGWSRAIFSVGPVSPSRRWSYRCYAYDSNSPHVWSLP 211
Query: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
SD LEL+V G KP+LS P P+V GE++TLQC S + +DRF+L +EG+ L
Sbjct: 212 SDLLELLVLGVSKKPSLSVQPGPIVAPGESLTLQCVSDVSYDRFVLYKEGERDF-LQLPG 270
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+G QA F +GPV+ S+ RC G+ ++ WS PSD L+I ++G
Sbjct: 271 PQPQAGLSQANFTLGPVSRSYGGQYRCSGA-YNLSSEWSAPSDPLDILIAG 320
Score = 52.4 bits (124), Expect = 5e-07
Identities = 37/113 (32%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE-PWD 76
A S L +L+ + + PG ++ G +VT+ CQ + L K G+ + P
Sbjct: 309 APSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKAGAADAPLR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTG 125
++ E PK +A F + +T H+G YRCY +P S PSD LEL+V+G
Sbjct: 369 LRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVSG 421
>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 4 [Homo sapiens]
Length = 651
Score = 217 bits (552), Expect = 1e-56
Identities = 122/229 (53%), Positives = 146/229 (63%), Gaps = 13/229 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
+F VGPV+PS RW RCY + WS PSDLLE+ V G + S S
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Score = 133 bits (334), Expect = 2e-31
Identities = 88/257 (34%), Positives = 138/257 (53%), Gaps = 11/257 (4%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTY-QSQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRM 257
RCYGS+ + + PSD LE+ VSG + PS + + S +D +
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG--GPSSPTTGPTSTSGPEDQPLTPTGSD 450
Query: 258 GMAGL---ILVVLGILI 271
+GL + VV+GIL+
Sbjct: 451 PQSGLGRHLGVVIGILV 467
Score = 128 bits (321), Expect = 7e-30
Identities = 81/233 (34%), Positives = 120/233 (51%), Gaps = 12/233 (5%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAG 320
Score = 69.3 bits (168), Expect = 4e-12
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTSG 143
S P TSG
Sbjct: 428 SPTTGPTSTSG 438
>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 3 [Homo sapiens]
Length = 651
Score = 217 bits (552), Expect = 1e-56
Identities = 122/229 (53%), Positives = 146/229 (63%), Gaps = 13/229 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
+F VGPV+PS RW RCY + WS PSDLLE+ V G + S S
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Score = 133 bits (335), Expect = 2e-31
Identities = 88/257 (34%), Positives = 139/257 (54%), Gaps = 10/257 (3%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTY-QSQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRM 257
RCYGS+ + + PSD LE+ VSG + S S + T++ +D +
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSAGPEDQPLTPTGSD 451
Query: 258 GMAGL---ILVVLGILI 271
+GL + VV+GIL+
Sbjct: 452 PQSGLGRHLGVVIGILV 468
Score = 128 bits (321), Expect = 7e-30
Identities = 81/233 (34%), Positives = 120/233 (51%), Gaps = 12/233 (5%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAG 320
Score = 67.0 bits (162), Expect = 2e-11
Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 6/130 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTS 142
S P TS
Sbjct: 428 SPTTGPTSTS 437
>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 2 [Homo sapiens]
Length = 652
Score = 217 bits (552), Expect = 1e-56
Identities = 122/229 (53%), Positives = 146/229 (63%), Gaps = 13/229 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
+F VGPV+PS RW RCY + WS PSDLLE+ V G + S S
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Score = 133 bits (335), Expect = 2e-31
Identities = 88/257 (34%), Positives = 139/257 (54%), Gaps = 10/257 (3%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTY-QSQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRM 257
RCYGS+ + + PSD LE+ VSG + S S + T++ +D +
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS-SPTTGPTSTSAGPEDQPLTPTGSD 451
Query: 258 GMAGL---ILVVLGILI 271
+GL + VV+GIL+
Sbjct: 452 PQSGLGRHLGVVIGILV 468
Score = 128 bits (321), Expect = 7e-30
Identities = 81/233 (34%), Positives = 120/233 (51%), Gaps = 12/233 (5%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAG 320
Score = 67.0 bits (162), Expect = 2e-11
Identities = 46/130 (35%), Positives = 67/130 (51%), Gaps = 6/130 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTS 142
S P TS
Sbjct: 428 SPTTGPTSTS 437
>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
member 1 isoform 1 [Homo sapiens]
Length = 650
Score = 217 bits (552), Expect = 1e-56
Identities = 122/229 (53%), Positives = 146/229 (63%), Gaps = 13/229 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI++G+ VT+RCQG E QEYRL
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSP-AGWSEPSDPLELVVTG 125
+E W T+ P E K +F IPS+T HAGRYRCYY S AG SE SDPLELVVTG
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y KPTLSA PSPVV SG NV LQC S++ FD F L +EG+ + L+SQ G +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
+F VGPV+PS RW RCY + WS PSDLLE+ V G + S S
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLS 229
Score = 133 bits (334), Expect = 2e-31
Identities = 88/257 (34%), Positives = 138/257 (53%), Gaps = 11/257 (4%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQN--P 80
L+ LL LG K +L +PG +++ ++T++C + L K+G + P
Sbjct: 214 LLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + WS PSDPL++++ G FY++ +LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG W L S S ++QA FP+GPVT +H
Sbjct: 334 PTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWRLRSTY-QSQKYQAEFPMGPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRM 257
RCYGS+ + + PSD LE+ VSG + PS + + S +D +
Sbjct: 393 GTYRCYGSQSSKPYLLTHPSDPLELVVSGPSG--GPSSPTTGPTSTSGPEDQPLTPTGSD 450
Query: 258 GMAGL---ILVVLGILI 271
+GL + VV+GIL+
Sbjct: 451 PQSGLGRHLGVVIGILV 467
Score = 128 bits (321), Expect = 7e-30
Identities = 81/233 (34%), Positives = 120/233 (51%), Gaps = 12/233 (5%)
Query: 4 WSHPSAQLQPVGGDAV----SPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTL 59
W H G D S + L+ G K TL A+P V++ G +V ++C +
Sbjct: 90 WEHAGRYRCYYGSDTAGRSESSDPLELVVTGAYIKPTLSAQPSPVVNSGGNVILQCDSQV 149
Query: 60 EAQEYRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWS 113
+ L KEG P+ ++Q ++A FS+ ++ YRCY Y SP WS
Sbjct: 150 AFDGFSLCKEGEDEHPQCLNSQPHARGSSRAIFSVGPVSPSRRWWYRCYAYDSNSPYEWS 209
Query: 114 EPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTL 173
PSD LEL+V G KP+LS P P+V E +TLQCGS ++RF+L ++G+
Sbjct: 210 LPSDLLELLVLGVSKKPSLSVQPGPIVAPEETLTLQCGSDAGYNRFVLYKDGERDFLQLA 269
Query: 174 DSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
+Q +G QA F +GPV+ S+ RCYG+ ++ WS PSD L+I ++G
Sbjct: 270 GAQ-PQAGLSQANFTLGPVSRSYGGQYRCYGA-HNLSSEWSAPSDPLDILIAG 320
Score = 69.3 bits (168), Expect = 4e-12
Identities = 47/131 (35%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG-SPEPWD 76
A S L +L+ + +L +PG ++ G +VT+ CQ Q + L KEG + +PW
Sbjct: 309 APSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKEGAADDPWR 368
Query: 77 TQNPLE-PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTGFYNKPTL 132
++ + K +A F + +T HAG YRCY P + PSDPLELVV+G P+
Sbjct: 369 LRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVSGPSGGPS- 427
Query: 133 SALPSPVVTSG 143
S P TSG
Sbjct: 428 SPTTGPTSTSG 438
>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform a [Homo sapiens]
Length = 483
Score = 215 bits (548), Expect = 3e-56
Identities = 119/228 (52%), Positives = 145/228 (63%), Gaps = 13/228 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI +G+ VT+RCQG+L+A+EY L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W + EP +F IPS+T HAGRY C YYS SE SDPLELVVTG
Sbjct: 61 YRENKSASW-VRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVVT G NVTLQC S++ FD FIL +EG+ + L+S G A+
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
F VGPV+PS RW RCY + VWS PSDLLE+ V G + S S
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLS 227
Score = 207 bits (526), Expect = 1e-53
Identities = 127/276 (46%), Positives = 171/276 (61%), Gaps = 15/276 (5%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE-----PWDT 77
L+ LL G K +L +PG +++ G S+T++C + + L KEG + W
Sbjct: 212 LLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQP 271
Query: 78 QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSA 134
Q L ++A F++ ++ H G+YRCY + + WS PSDPL++++TG FY++P+LS
Sbjct: 272 QAGL---SQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSV 328
Query: 135 LPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTP 194
P P V G+NVTL C SR +F F+LT+EG L S+ + Q QA F +GPVT
Sbjct: 329 QPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSE-HQAQQNQAEFRMGPVTS 387
Query: 195 SHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTAS---HLQDYAV 251
+H RCY S + S PSD LE+ VS AA+ LSPSQNK+DS T S H QDY V
Sbjct: 388 AHVGTYRCYSSLSSNPYLLSLPSDPLELVVSEAAETLSPSQNKTDSTTTSLGQHPQDYTV 447
Query: 252 ENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
ENLIRMG+AGL+LVVLGIL+F+ HSQRS Q AAGR
Sbjct: 448 ENLIRMGVAGLVLVVLGILLFEAQHSQRSLQDAAGR 483
Score = 130 bits (326), Expect = 2e-30
Identities = 81/207 (39%), Positives = 115/207 (55%), Gaps = 8/207 (3%)
Query: 26 LLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLE 82
L+ G SK TL A P V++ G +VT++C + + L KEG P+ ++ +
Sbjct: 114 LVVTGAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHAR 173
Query: 83 PKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPV 139
+ A FS+ ++ YRCY Y SP WS PSD LEL+V G KP+LS P P+
Sbjct: 174 GWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPM 233
Query: 140 VTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWM 199
V GE++TLQC S + +DRF+L +EG+ Q +G QA F +GPV+PSH
Sbjct: 234 VAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQ-PQAGLSQANFTLGPVSPSHGGQ 292
Query: 200 LRCYGSRRHILQVWSEPSDLLEIPVSG 226
RCY S ++ WS PSD L+I ++G
Sbjct: 293 YRCY-SAHNLSSEWSAPSDPLDILITG 318
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT 77
A S L +L+ + +L +P ++ G +VT+ CQ + + L KEG+ P
Sbjct: 307 APSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHP--- 363
Query: 78 QNPLE-------PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVT 124
PL +N+A F + +T H G YRCY +P S PSDPLELVV+
Sbjct: 364 --PLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVS 418
>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A
(with TM domain), member 2 isoform b [Homo sapiens]
Length = 466
Score = 215 bits (548), Expect = 3e-56
Identities = 119/228 (52%), Positives = 145/228 (63%), Gaps = 13/228 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG +L K TLWAEPGSVI +G+ VT+RCQG+L+A+EY L
Sbjct: 1 MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W + EP +F IPS+T HAGRY C YYS SE SDPLELVVTG
Sbjct: 61 YRENKSASW-VRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+KPTLSALPSPVVT G NVTLQC S++ FD FIL +EG+ + L+S G A+
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
F VGPV+PS RW RCY + VWS PSDLLE+ V G + S S
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLS 227
Score = 179 bits (454), Expect = 2e-45
Identities = 114/273 (41%), Positives = 157/273 (57%), Gaps = 26/273 (9%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE-----PWDT 77
L+ LL G K +L +PG +++ G S+T++C + + L KEG + W
Sbjct: 212 LLELLVPGVSKKPSLSVQPGPMVAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQP 271
Query: 78 QNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSA 134
Q L ++A F++ ++ H G+YRCY + + WS PSDPL++++TG FY++P+LS
Sbjct: 272 QAGL---SQANFTLGPVSPSHGGQYRCYSAHNLSSEWSAPSDPLDILITGQFYDRPSLSV 328
Query: 135 LPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTP 194
P P V G+NVTL C SR +F F+LT+EG L S+ + Q QA F +GPVT
Sbjct: 329 QPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHPPLHLRSE-HQAQQNQAEFRMGPVTS 387
Query: 195 SHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENL 254
+H RCY S + S PSD LE+ VS + H QDY VENL
Sbjct: 388 AHVGTYRCYSSLSSNPYLLSLPSDPLELVVSASL--------------GQHPQDYTVENL 433
Query: 255 IRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
IRMG+AGL+LVVLGIL+F+ HSQRS Q AAGR
Sbjct: 434 IRMGVAGLVLVVLGILLFEAQHSQRSLQDAAGR 466
Score = 130 bits (326), Expect = 2e-30
Identities = 81/207 (39%), Positives = 115/207 (55%), Gaps = 8/207 (3%)
Query: 26 LLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLE 82
L+ G SK TL A P V++ G +VT++C + + L KEG P+ ++ +
Sbjct: 114 LVVTGAYSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHAR 173
Query: 83 PKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPV 139
+ A FS+ ++ YRCY Y SP WS PSD LEL+V G KP+LS P P+
Sbjct: 174 GWSWAIFSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPM 233
Query: 140 VTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWM 199
V GE++TLQC S + +DRF+L +EG+ Q +G QA F +GPV+PSH
Sbjct: 234 VAPGESLTLQCVSDVGYDRFVLYKEGERDFLQRPGWQ-PQAGLSQANFTLGPVSPSHGGQ 292
Query: 200 LRCYGSRRHILQVWSEPSDLLEIPVSG 226
RCY S ++ WS PSD L+I ++G
Sbjct: 293 YRCY-SAHNLSSEWSAPSDPLDILITG 318
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/117 (33%), Positives = 57/117 (48%), Gaps = 15/117 (12%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT 77
A S L +L+ + +L +P ++ G +VT+ CQ + + L KEG+ P
Sbjct: 307 APSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEGAGHP--- 363
Query: 78 QNPLE-------PKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVT 124
PL +N+A F + +T H G YRCY +P S PSDPLELVV+
Sbjct: 364 --PLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVS 418
>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 1 [Homo sapiens]
Length = 598
Score = 214 bits (544), Expect = 9e-56
Identities = 116/228 (50%), Positives = 144/228 (63%), Gaps = 12/228 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P + VL+CLG + K TLWAEP SVI++G+ VT+ CQG+LEAQEYRL
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W T+ E +F IPS+T H GRY C YYS A WSE SDPL LV+TG
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y KPTLSA PSPVVTSG VTLQC S++ F FIL +EG+ + L+SQ G +A+
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
F VGPV+P+ RW RCYG + VWS PSDLLE+ V G + S S
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLS 228
Score = 132 bits (331), Expect = 5e-31
Identities = 80/209 (38%), Positives = 120/209 (57%), Gaps = 8/209 (3%)
Query: 24 MVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNP 80
+VL+ G K TL A+P V++ G VT++C+ + + L KEG P+ ++Q
Sbjct: 113 LVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPH 172
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPS 137
++A FS+ ++ + +RCY Y SP WS PSD LEL+V G KP+LS P
Sbjct: 173 ARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPG 232
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
PVV GE++TLQC S + +DRF+L +EG+ L L + +G QA F +GPV+ S+
Sbjct: 233 PVVAPGESLTLQCVSDVGYDRFVLYKEGERDLR-QLPGRQPQAGLSQANFTLGPVSRSYG 291
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
RCYG+ ++ S PSD L+I ++G
Sbjct: 292 GQYRCYGA-HNLSSECSAPSDPLDILITG 319
Score = 120 bits (302), Expect = 1e-27
Identities = 77/216 (35%), Positives = 116/216 (53%), Gaps = 6/216 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE--PWDTQNP 80
L+ LL G K +L +PG V++ G S+T++C + + L KEG + + P
Sbjct: 213 LLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQP 272
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + S PSDPL++++TG P +S P
Sbjct: 273 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPG 332
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S +F F+LT+ G L S + ++QA FP+ PVT +H
Sbjct: 333 PTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRS-IHEYPKYQAEFPMSPVTSAHA 391
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSP 233
RCYGS + S PS+ LE+ VSG + SP
Sbjct: 392 GTYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSP 427
>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
member 2 isoform 2 [Homo sapiens]
Length = 597
Score = 214 bits (544), Expect = 9e-56
Identities = 116/228 (50%), Positives = 144/228 (63%), Gaps = 12/228 (5%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P + VL+CLG + K TLWAEP SVI++G+ VT+ CQG+LEAQEYRL
Sbjct: 1 MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
+E W T+ E +F IPS+T H GRY C YYS A WSE SDPL LV+TG
Sbjct: 61 YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y KPTLSA PSPVVTSG VTLQC S++ F FIL +EG+ + L+SQ G +A+
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
F VGPV+P+ RW RCYG + VWS PSDLLE+ V G + S S
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLS 228
Score = 132 bits (331), Expect = 5e-31
Identities = 80/209 (38%), Positives = 120/209 (57%), Gaps = 8/209 (3%)
Query: 24 MVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNP 80
+VL+ G K TL A+P V++ G VT++C+ + + L KEG P+ ++Q
Sbjct: 113 LVLVMTGAYPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPH 172
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPS 137
++A FS+ ++ + +RCY Y SP WS PSD LEL+V G KP+LS P
Sbjct: 173 ARGSSRAIFSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPG 232
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
PVV GE++TLQC S + +DRF+L +EG+ L L + +G QA F +GPV+ S+
Sbjct: 233 PVVAPGESLTLQCVSDVGYDRFVLYKEGERDLR-QLPGRQPQAGLSQANFTLGPVSRSYG 291
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
RCYG+ ++ S PSD L+I ++G
Sbjct: 292 GQYRCYGA-HNLSSECSAPSDPLDILITG 319
Score = 120 bits (302), Expect = 1e-27
Identities = 77/216 (35%), Positives = 116/216 (53%), Gaps = 6/216 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPE--PWDTQNP 80
L+ LL G K +L +PG V++ G S+T++C + + L KEG + + P
Sbjct: 213 LLELLVPGVSKKPSLSVQPGPVVAPGESLTLQCVSDVGYDRFVLYKEGERDLRQLPGRQP 272
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPS 137
++A F++ ++ + G+YRCY + + S PSDPL++++TG P +S P
Sbjct: 273 QAGLSQANFTLGPVSRSYGGQYRCYGAHNLSSECSAPSDPLDILITGQIRGTPFISVQPG 332
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S +F F+LT+ G L S + ++QA FP+ PVT +H
Sbjct: 333 PTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRS-IHEYPKYQAEFPMSPVTSAHA 391
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSP 233
RCYGS + S PS+ LE+ VSG + SP
Sbjct: 392 GTYRCYGSLNSDPYLLSHPSEPLELVVSGPSMGSSP 427
>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
(without TM domain), member 3 [Homo sapiens]
Length = 439
Score = 213 bits (543), Expect = 1e-55
Identities = 120/225 (53%), Positives = 143/225 (63%), Gaps = 13/225 (5%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEPGSVI++G+ VT+RCQG+LE QEY L +E
Sbjct: 5 LTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREK 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS-PAGWSEPSDPLELVVTGFYNK 129
W T+ P E K +F I S+T HAGRY C Y S G SE SDPLELVVTG Y+K
Sbjct: 65 KTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLELVVTGAYSK 124
Query: 130 PTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPV 189
PTLSALPSPVVTSG NVT+QC S++ FD FIL +EG+ + L+S G +A+F V
Sbjct: 125 PTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSV 184
Query: 190 GPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
GPV+PS RW RCYG VWS PSDLL + V G + S S
Sbjct: 185 GPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLS 229
Score = 136 bits (343), Expect = 2e-32
Identities = 86/223 (38%), Positives = 122/223 (54%), Gaps = 6/223 (2%)
Query: 23 LMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT--QNP 80
L+ LL G K +L +PG V++ G +T +C + L KE + + P
Sbjct: 214 LLGLLVPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQP 273
Query: 81 LEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTGFYN-KPTLSALPS 137
++A F++ ++ + G+Y C Y + WS PSDPL++++TG +P LS P
Sbjct: 274 QAGLSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPG 333
Query: 138 PVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHR 197
P V SGENVTL C S+ F+LT+EG L S+ S ++QA FP+ PVT +H
Sbjct: 334 PTVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSK-RQSHKYQAEFPMSPVTSAHA 392
Query: 198 WMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDS 240
RCYGS + + PSD LE+ VSGAA+ LSP QNKSDS
Sbjct: 393 GTYRCYGSLSSNPYLLTHPSDPLELVVSGAAETLSPPQNKSDS 435
Score = 119 bits (298), Expect = 3e-27
Identities = 78/212 (36%), Positives = 111/212 (52%), Gaps = 18/212 (8%)
Query: 26 LLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLE 82
L+ G SK TL A P V++ G +VTI+C + + L KEG P+ ++ +
Sbjct: 116 LVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHAR 175
Query: 83 PKNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPV 139
++A FS+ ++ YRCY Y +P WS PSD L L+V G KP+LS P PV
Sbjct: 176 GSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPV 235
Query: 140 VTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTP-----SGQFQALFPVGPVTP 194
V GE +T QCGS +DRF+L +E W D P +G QA F +GPV+
Sbjct: 236 VAPGEKLTFQCGSDAGYDRFVLYKE------WGRDFLQRPGRQPQAGLSQANFTLGPVSR 289
Query: 195 SHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
S+ C G+ ++ WS PSD L+I ++G
Sbjct: 290 SYGGQYTCSGA-YNLSSEWSAPSDPLDILITG 320
Score = 58.5 bits (140), Expect = 6e-09
Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 15/118 (12%)
Query: 18 AVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDT 77
A S L +L+ ++ L PG ++ G +VT+ CQ + L KEG+ +
Sbjct: 309 APSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKEGAAD---- 364
Query: 78 QNPLEPKNK-------ARFSIPSMTEHHAGRYRCY---YYSPAGWSEPSDPLELVVTG 125
+PL K+K A F + +T HAG YRCY +P + PSDPLELVV+G
Sbjct: 365 -SPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVSG 421
>gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like
receptor, partial [Homo sapiens]
Length = 256
Score = 212 bits (539), Expect = 3e-55
Identities = 121/229 (52%), Positives = 146/229 (63%), Gaps = 14/229 (6%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
++P L VL+CLG L K TLWAEPGSVI++G+ VT+RCQG+LE QEY L
Sbjct: 1 MTPILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYS-PAGWSEPSDPLELVVTG 125
+E W T+ P E K +F I S+T HAGRY C Y S AG SE SDPLELVVT
Sbjct: 61 YREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTA 120
Query: 126 FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQA 185
Y+KPTLSALPSPVVTSG NVT+QC S++ FD FIL +EG+ + L+S G +A
Sbjct: 121 -YSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRA 179
Query: 186 LFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPS 234
+F VGPV+PS RW RCYG VWS PSDLL + V G + S S
Sbjct: 180 IFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLS 228
Score = 93.6 bits (231), Expect = 2e-19
Identities = 54/135 (40%), Positives = 75/135 (55%), Gaps = 6/135 (4%)
Query: 33 SKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLEPKNKARF 89
SK TL A P V++ G +VTI+C + + L KEG P+ ++ + ++A F
Sbjct: 122 SKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIF 181
Query: 90 SIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 146
S+ ++ YRCY Y +P WS PSD L L+V G KP+LS P PVV GE +
Sbjct: 182 SVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEKL 241
Query: 147 TLQCGSRLRFDRFIL 161
T QCGS +DRF+L
Sbjct: 242 TFQCGSDPGYDRFVL 256
>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
member 5 isoform 3 [Homo sapiens]
Length = 491
Score = 196 bits (499), Expect = 2e-50
Identities = 110/216 (50%), Positives = 133/216 (61%), Gaps = 14/216 (6%)
Query: 23 LMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 70
L VL+CLG L K TLWAEP SVI+RG VT+ CQG LE +EYRL KEG
Sbjct: 5 LSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG 64
Query: 71 SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 130
P QNPLEP KA+F IPS AGRYRCYY +PAGWSEPSDPLELV TG KP
Sbjct: 65 LPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGVSRKP 124
Query: 131 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 190
+L VV G ++TLQC S + +D F+L +EG+H L Q +G QA F +G
Sbjct: 125 SLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQANFTLG 183
Query: 191 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226
PV+ SH RCYG+ ++ WS PSD L+I ++G
Sbjct: 184 PVSRSHGGQYRCYGA-HNLSPRWSAPSDPLDILIAG 218
Score = 117 bits (294), Expect = 9e-27
Identities = 86/241 (35%), Positives = 122/241 (50%), Gaps = 23/241 (9%)
Query: 2 APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61
A WS PS L+ L+ G K +L GSV++RG S+T++C+ +
Sbjct: 104 AGWSEPSDPLE-------------LVATGVSRKPSLLIPQGSVVARGGSLTLQCRSDVGY 150
Query: 62 QEYRLVKEGSPE--PWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSEPS 116
+ L KEG + Q P ++A F++ ++ H G+YRCY SP WS PS
Sbjct: 151 DIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNLSPR-WSAPS 209
Query: 117 DPLELVVTGFY-NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175
DPL++++ G + P LS P P V SGENVTL C S + D F LT+EG L S
Sbjct: 210 DPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHPPLCLKS 269
Query: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA--DNLSP 233
+ S + QA F + PVT + RCY + R + S PS E+ VSG + +LSP
Sbjct: 270 KY-QSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSP 328
Query: 234 S 234
+
Sbjct: 329 T 329
Score = 55.1 bits (131), Expect = 7e-08
Identities = 41/117 (35%), Positives = 55/117 (47%), Gaps = 15/117 (12%)
Query: 37 LWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNK-------ARF 89
L +PG ++ G +VT+ CQ + + L KEG+ P PL K+K A F
Sbjct: 226 LSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAAHP-----PLCLKSKYQSYRHQAEF 280
Query: 90 SIPSMTEHHAGRYRCYYYS---PAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSG 143
S+ +T G YRCY P S PS P ELVV+G P+LS S +G
Sbjct: 281 SMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPSGDPSLSPTGSTPTPAG 337
>gi|224586788 natural cytotoxicity triggering receptor 1 isoform c
[Homo sapiens]
Length = 287
Score = 168 bits (426), Expect = 4e-42
Identities = 109/282 (38%), Positives = 145/282 (51%), Gaps = 23/282 (8%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
+S L LLC+G L K +WAEP ++ + VTI CQG A EY+L
Sbjct: 1 MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
EGS D P E NK +F IP M AG+Y C Y WSEPS+ L+LVVT
Sbjct: 61 HFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEM 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+ PTLS P P V SGE VT C F+L +EG G+ QA
Sbjct: 121 YDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEG------RSSHVQRGYGKVQAE 174
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASH- 245
FP+GPVT +HR RC+GS + WS PS+ +++ V+G +N S + D H
Sbjct: 175 FPLGPVTTAHRGTYRCFGSYNN--HAWSFPSEPVKLLVTGDIENTSLA--PEDPTFPDHA 230
Query: 246 LQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
L D+ +NL+RMG+A L+LV L + +DW S++ + A R
Sbjct: 231 LWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASR 272
>gi|4758692 natural cytotoxicity triggering receptor 1 isoform a
[Homo sapiens]
Length = 304
Score = 163 bits (413), Expect = 1e-40
Identities = 111/297 (37%), Positives = 147/297 (49%), Gaps = 36/297 (12%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
+S L LLC+G L K +WAEP ++ + VTI CQG A EY+L
Sbjct: 1 MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
EGS D P E NK +F IP M AG+Y C Y WSEPS+ L+LVVT
Sbjct: 61 HFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEM 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+ PTLS P P V SGE VT C F+L +EG G+ QA
Sbjct: 121 YDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEG------RSSHVQRGYGKVQAE 174
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLS-----PSQNKSDSG 241
FP+GPVT +HR RC+GS + WS PS+ +++ V+G +N S P+ G
Sbjct: 175 FPLGPVTTAHRGTYRCFGSYNN--HAWSFPSEPVKLLVTGDIENTSLAPEDPTFPADTWG 232
Query: 242 T----------ASH-LQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
T H L D+ +NL+RMG+A L+LV L + +DW S++ + A R
Sbjct: 233 TYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASR 289
>gi|224586786 natural cytotoxicity triggering receptor 1 isoform b
[Homo sapiens]
Length = 303
Score = 163 bits (412), Expect = 2e-40
Identities = 108/296 (36%), Positives = 147/296 (49%), Gaps = 35/296 (11%)
Query: 19 VSPALMVLLCLG------------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRL 66
+S L LLC+G L K +WAEP ++ + VTI CQG A EY+L
Sbjct: 1 MSSTLPALLCVGLCLSQRISAQQQTLPKPFIWAEPHFMVPKEKQVTICCQGNYGAVEYQL 60
Query: 67 VKEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGF 126
EGS D P E NK +F IP M AG+Y C Y WSEPS+ L+LVVT
Sbjct: 61 HFEGSLFAVDRPKPPERINKVKFYIPDMNSRMAGQYSCIYRVGELWSEPSNLLDLVVTEM 120
Query: 127 YNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQAL 186
Y+ PTLS P P V SGE VT C F+L +EG G+ QA
Sbjct: 121 YDTPTLSVHPGPEVISGEKVTFYCRLDTATSMFLLLKEG------RSSHVQRGYGKVQAE 174
Query: 187 FPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQN---------- 236
FP+GPVT +HR RC+GS + WS PS+ +++ V+G +N S +
Sbjct: 175 FPLGPVTTAHRGTYRCFGSYNN--HAWSFPSEPVKLLVTGDIENTSLAPEDPTFPDTWGT 232
Query: 237 ---KSDSGTASH--LQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQAAAGR 287
+++G L D+ +NL+RMG+A L+LV L + +DW S++ + A R
Sbjct: 233 YLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASR 288
>gi|143770755 glycoprotein VI (platelet) isoform 2 [Homo sapiens]
Length = 339
Score = 152 bits (385), Expect = 3e-37
Identities = 107/318 (33%), Positives = 145/318 (45%), Gaps = 64/318 (20%)
Query: 19 VSPALMVLLCLG-----------NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLV 67
+SP+ L CLG L K +L A P S++ VT+RCQG YRL
Sbjct: 1 MSPSPTALFCLGLCLGRVPAQSGPLPKPSLQALPSSLVPLEKPVTLRCQGPPGVDLYRLE 60
Query: 68 KEGSPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFY 127
K S D +A IP+M AGRYRC Y + + WS PSD LELV TG +
Sbjct: 61 KLSSSRYQD---------QAVLFIPAMKRSLAGRYRCSYQNGSLWSLPSDQLELVATGVF 111
Query: 128 NKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALF 187
KP+LSA P P V+SG +VTLQC +R FD+F L +EGD P ++A F
Sbjct: 112 AKPSLSAQPGPAVSSGGDVTLQCQTRYGFDQFALYKEGDPA------PYKNPERWYRASF 165
Query: 188 PVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG--------------------- 226
P+ VT +H RCY +WS PSD LE+ V+G
Sbjct: 166 PIITVTAAHSGTYRCYSFSSRDPYLWSAPSDPLELVVTGTSVTPSRLPTEPPSPVAEFSE 225
Query: 227 -----------------AADNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGLILVVLGI 269
+ +++ S +SDS Q Y NL+R+ + +IL++L
Sbjct: 226 ATAELTVSFTNEVFTTETSRSITASPKESDSPAGPARQYYTKGNLVRICLGAVILIILAG 285
Query: 270 LIFQDWHSQRSPQAAAGR 287
+ +DWHS+R GR
Sbjct: 286 FLAEDWHSRRKRLRHRGR 303
>gi|134133244 killer cell immunoglobulin-like receptor, three
domains, short cytoplasmic tail, 1 [Homo sapiens]
Length = 382
Score = 149 bits (376), Expect = 3e-36
Identities = 102/275 (37%), Positives = 145/275 (52%), Gaps = 24/275 (8%)
Query: 5 SHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEY 64
SHP + P G A S MV++ GN K +L A PG ++ G V ++C + + +
Sbjct: 98 SHPHS---PTGWSAPSNP-MVIMVTGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHF 153
Query: 65 RLVKEGSPEPWDTQNPL-------EPKNKARFSIPSMTEHHAGRYRCY---YYSPAGWSE 114
L KE W +++P + +KA FSI SM AG YRCY ++P S
Sbjct: 154 FLHKE-----WISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVTHTPYQLSA 208
Query: 115 PSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLD 174
PSDPL++VVTG Y KP+LSA P P V +GE+VTL C SR +D + L+ EG L
Sbjct: 209 PSDPLDIVVTGLYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAH-ERRLP 267
Query: 175 SQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNL--S 232
+ + FQA FP+GP T H RC+GS RH WS+PSD L + V+G + S
Sbjct: 268 AVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVSVTGNPSSSWPS 325
Query: 233 PSQNKSDSGTASHLQDYAVENLIRMGMAGLILVVL 267
P++ S SG HL +++++ L+ +L
Sbjct: 326 PTEPSSKSGNLRHLHILIGTSVVKIPFTILLFFLL 360
Score = 110 bits (276), Expect = 1e-24
Identities = 75/209 (35%), Positives = 105/209 (50%), Gaps = 7/209 (3%)
Query: 29 LGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKAR 88
+G K L A P +V+ RG VT+RC + L KE + +
Sbjct: 23 MGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIFHGRIFQEG--- 79
Query: 89 FSIPSMTEHHAGRYRC---YYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGEN 145
F++ +T HAG Y C + +SP GWS PS+P+ ++VTG + KP+L A P P+V SGE
Sbjct: 80 FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGER 139
Query: 146 VTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGS 205
V LQC S + F+ F L +E K L Q+ G +A F +G + + RCYGS
Sbjct: 140 VILQCWSDIMFEHFFLHKEWISKDPSRLVGQI-HDGVSKANFSIGSMMRALAGTYRCYGS 198
Query: 206 RRHILQVWSEPSDLLEIPVSGAADNLSPS 234
H S PSD L+I V+G + S S
Sbjct: 199 VTHTPYQLSAPSDPLDIVVTGLYEKPSLS 227
>gi|124107606 killer cell immunoglobulin-like receptor, two domains,
long cytoplasmic tail, 4 isoform a [Homo sapiens]
Length = 377
Score = 147 bits (370), Expect = 1e-35
Identities = 101/288 (35%), Positives = 149/288 (51%), Gaps = 38/288 (13%)
Query: 18 AVSPALMVLLCLGNLSKATLWAE------------PGSVISRGNSVTIRCQGTLEAQEYR 65
++SP +++L CLG ++WA P +V+ +G VT+RC +
Sbjct: 2 SMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIFT 61
Query: 66 LVK-EGSPEPWDTQNPLEPKNKA---RFSIPSMTEHHAGRYRC---YYYSPAGWSEPSDP 118
L K +G P P E N+ F I +T HAG YRC + +SP WS PS+P
Sbjct: 62 LYKKDGVPVP-------ELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNP 114
Query: 119 LELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGD-HKLSWTLDSQL 177
L ++VTG Y KP+L+A P P V +GENVTL C S+ FD + L+ EG+ H+L L +
Sbjct: 115 LVIMVTGLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHEL--RLPAVP 172
Query: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNL--SPSQ 235
+ +G FQA FP+GP T H RC+GS WS+PSD L + V+G + SP++
Sbjct: 173 SINGTFQADFPLGPAT--HGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTE 230
Query: 236 NKSDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSPQA 283
+G A HL +IR +A ++ +L + W S++ A
Sbjct: 231 PSFKTGIARHL-----HAVIRYSVAIILFTILPFFLLHRWCSKKKNAA 273
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,745,667
Number of Sequences: 37866
Number of extensions: 635372
Number of successful extensions: 2449
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 1564
Number of HSP's gapped (non-prelim): 405
length of query: 287
length of database: 18,247,518
effective HSP length: 101
effective length of query: 186
effective length of database: 14,423,052
effective search space: 2682687672
effective search space used: 2682687672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.