Guide to the Human Genome
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Search of human proteins with 32484987

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32484987 hepatocellular carcinoma-associated antigen 112
[Homo sapiens]
         (235 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32484987 hepatocellular carcinoma-associated antigen 112 [Hom...   474   e-134
gi|156416020 transmembrane protein 176B isoform a [Homo sapiens]      106   2e-23
gi|156416018 transmembrane protein 176B isoform a [Homo sapiens]      106   2e-23
gi|156416016 transmembrane protein 176B isoform a [Homo sapiens]      106   2e-23
gi|156416014 transmembrane protein 176B isoform a [Homo sapiens]      106   2e-23
gi|156416022 transmembrane protein 176B isoform b [Homo sapiens]       67   1e-11
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]       30   1.8  
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo...    30   1.8  
gi|226437592 transmembrane protein 114 [Homo sapiens]                  30   1.8  
gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo sapi...    29   3.1  
gi|149944536 ichthyin protein [Homo sapiens]                           29   3.1  
gi|4507035 solute carrier family 5 (sodium iodide symporter), me...    29   3.1  
gi|23110997 membrane-spanning 4-domains, subfamily A, member 5 [...    29   3.1  
gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]       29   4.0  
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]          28   5.2  
gi|215983058 magnesium transporter 1 [Homo sapiens]                    28   6.8  

>gi|32484987 hepatocellular carcinoma-associated antigen 112 [Homo
           sapiens]
          Length = 235

 Score =  474 bits (1220), Expect = e-134
 Identities = 235/235 (100%), Positives = 235/235 (100%)

Query: 1   MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVM 60
           MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVM
Sbjct: 1   MGTADSDEMAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVM 60

Query: 61  QIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTL 120
           QIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTL
Sbjct: 61  QIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTL 120

Query: 121 LTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSF 180
           LTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSF
Sbjct: 121 LTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAPTQSPEEVRRLHLCTSF 180

Query: 181 MDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI 235
           MDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI
Sbjct: 181 MDMLKALFRTLQAMLLGVWILLLLASLTPLWLYCWRMFPTKGKRDQKEMLEVSGI 235


>gi|156416020 transmembrane protein 176B isoform a [Homo sapiens]
          Length = 270

 Score =  106 bits (264), Expect = 2e-23
 Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 15/215 (6%)

Query: 9   MAPEAPQHTHIDVHIHQESALAKLLLTCCSALR--------PRATQARGSSRLLVASWVM 60
           MA    Q TH++VHIHQESAL +LL    S  +          +T   G  +L +   V 
Sbjct: 13  MASRPSQPTHVNVHIHQESALTQLLKAGGSLKKFLFHPGDTVPSTARIGYEQLALG--VT 70

Query: 61  QIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTL 120
           QI+LG++S VLG    +  +T+L  SG A W G+V + AGA A ++EK  G     + +L
Sbjct: 71  QILLGVVSCVLGVCLSLGPWTVLSASGCAFWAGSVVIAAGAGAIVHEKHPGKLAGYISSL 130

Query: 121 LTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAP-----TQSPEEVRRLH 175
           LTLA F+TA+AA+ L    F +    +     +   SD   P        +S E   +  
Sbjct: 131 LTLAGFATAMAAVVLCVNSFIWQTEPFLYIDTVCDRSDPVFPTTGYRWMRRSQENQWQKE 190

Query: 176 LCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPL 210
            C ++M ML+ LF  ++A+ L V +L ++ SL  L
Sbjct: 191 ECRAYMQMLRKLFTAIRALFLAVCVLKVIVSLVSL 225


>gi|156416018 transmembrane protein 176B isoform a [Homo sapiens]
          Length = 270

 Score =  106 bits (264), Expect = 2e-23
 Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 15/215 (6%)

Query: 9   MAPEAPQHTHIDVHIHQESALAKLLLTCCSALR--------PRATQARGSSRLLVASWVM 60
           MA    Q TH++VHIHQESAL +LL    S  +          +T   G  +L +   V 
Sbjct: 13  MASRPSQPTHVNVHIHQESALTQLLKAGGSLKKFLFHPGDTVPSTARIGYEQLALG--VT 70

Query: 61  QIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTL 120
           QI+LG++S VLG    +  +T+L  SG A W G+V + AGA A ++EK  G     + +L
Sbjct: 71  QILLGVVSCVLGVCLSLGPWTVLSASGCAFWAGSVVIAAGAGAIVHEKHPGKLAGYISSL 130

Query: 121 LTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAP-----TQSPEEVRRLH 175
           LTLA F+TA+AA+ L    F +    +     +   SD   P        +S E   +  
Sbjct: 131 LTLAGFATAMAAVVLCVNSFIWQTEPFLYIDTVCDRSDPVFPTTGYRWMRRSQENQWQKE 190

Query: 176 LCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPL 210
            C ++M ML+ LF  ++A+ L V +L ++ SL  L
Sbjct: 191 ECRAYMQMLRKLFTAIRALFLAVCVLKVIVSLVSL 225


>gi|156416016 transmembrane protein 176B isoform a [Homo sapiens]
          Length = 270

 Score =  106 bits (264), Expect = 2e-23
 Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 15/215 (6%)

Query: 9   MAPEAPQHTHIDVHIHQESALAKLLLTCCSALR--------PRATQARGSSRLLVASWVM 60
           MA    Q TH++VHIHQESAL +LL    S  +          +T   G  +L +   V 
Sbjct: 13  MASRPSQPTHVNVHIHQESALTQLLKAGGSLKKFLFHPGDTVPSTARIGYEQLALG--VT 70

Query: 61  QIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTL 120
           QI+LG++S VLG    +  +T+L  SG A W G+V + AGA A ++EK  G     + +L
Sbjct: 71  QILLGVVSCVLGVCLSLGPWTVLSASGCAFWAGSVVIAAGAGAIVHEKHPGKLAGYISSL 130

Query: 121 LTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAP-----TQSPEEVRRLH 175
           LTLA F+TA+AA+ L    F +    +     +   SD   P        +S E   +  
Sbjct: 131 LTLAGFATAMAAVVLCVNSFIWQTEPFLYIDTVCDRSDPVFPTTGYRWMRRSQENQWQKE 190

Query: 176 LCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPL 210
            C ++M ML+ LF  ++A+ L V +L ++ SL  L
Sbjct: 191 ECRAYMQMLRKLFTAIRALFLAVCVLKVIVSLVSL 225


>gi|156416014 transmembrane protein 176B isoform a [Homo sapiens]
          Length = 270

 Score =  106 bits (264), Expect = 2e-23
 Identities = 74/215 (34%), Positives = 110/215 (51%), Gaps = 15/215 (6%)

Query: 9   MAPEAPQHTHIDVHIHQESALAKLLLTCCSALR--------PRATQARGSSRLLVASWVM 60
           MA    Q TH++VHIHQESAL +LL    S  +          +T   G  +L +   V 
Sbjct: 13  MASRPSQPTHVNVHIHQESALTQLLKAGGSLKKFLFHPGDTVPSTARIGYEQLALG--VT 70

Query: 61  QIVLGILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTL 120
           QI+LG++S VLG    +  +T+L  SG A W G+V + AGA A ++EK  G     + +L
Sbjct: 71  QILLGVVSCVLGVCLSLGPWTVLSASGCAFWAGSVVIAAGAGAIVHEKHPGKLAGYISSL 130

Query: 121 LTLAAFSTAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAP-----TQSPEEVRRLH 175
           LTLA F+TA+AA+ L    F +    +     +   SD   P        +S E   +  
Sbjct: 131 LTLAGFATAMAAVVLCVNSFIWQTEPFLYIDTVCDRSDPVFPTTGYRWMRRSQENQWQKE 190

Query: 176 LCTSFMDMLKALFRTLQAMLLGVWILLLLASLTPL 210
            C ++M ML+ LF  ++A+ L V +L ++ SL  L
Sbjct: 191 ECRAYMQMLRKLFTAIRALFLAVCVLKVIVSLVSL 225


>gi|156416022 transmembrane protein 176B isoform b [Homo sapiens]
          Length = 233

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 62/208 (29%), Positives = 92/208 (44%), Gaps = 38/208 (18%)

Query: 9   MAPEAPQHTHIDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILS 68
           MA    Q TH++VHIHQESAL +LL            +A GS                  
Sbjct: 13  MASRPSQPTHVNVHIHQESALTQLL------------KAGGS------------------ 42

Query: 69  AVLGGFFYIRDYTLLVTSGAAIWTGAVAVLA-GAAAFIYEKRGGTYWALLRTLLTLAAFS 127
             L  F +    T+  T+       A+ V+A GA A ++EK  G     + +LLTLA F+
Sbjct: 43  --LKKFLFHPGDTVPSTARIGYEQLALGVIAAGAGAIVHEKHPGKLAGYISSLLTLAGFA 100

Query: 128 TAIAALKLWNEDFRYGYSYYNSACRISSSSDWNTPAP-----TQSPEEVRRLHLCTSFMD 182
           TA+AA+ L    F +    +     +   SD   P        +S E   +   C ++M 
Sbjct: 101 TAMAAVVLCVNSFIWQTEPFLYIDTVCDRSDPVFPTTGYRWMRRSQENQWQKEECRAYMQ 160

Query: 183 MLKALFRTLQAMLLGVWILLLLASLTPL 210
           ML+ LF  ++A+ L V +L ++ SL  L
Sbjct: 161 MLRKLFTAIRALFLAVCVLKVIVSLVSL 188


>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 7/68 (10%)

Query: 45  TQARGSSRLLV--ASWVMQIVLGILSAVLGGF-----FYIRDYTLLVTSGAAIWTGAVAV 97
           T +  S +LL    ++V+ + L ++  V GG      F ++ Y LL+ +G     GA+  
Sbjct: 91  TVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVT 150

Query: 98  LAGAAAFI 105
           LAG + +I
Sbjct: 151 LAGISVYI 158


>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
           sapiens]
          Length = 217

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 7/68 (10%)

Query: 45  TQARGSSRLLV--ASWVMQIVLGILSAVLGGF-----FYIRDYTLLVTSGAAIWTGAVAV 97
           T +  S +LL    ++V+ + L ++  V GG      F ++ Y LL+ +G     GA+  
Sbjct: 85  TVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVT 144

Query: 98  LAGAAAFI 105
           LAG + +I
Sbjct: 145 LAGISVYI 152


>gi|226437592 transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 30.0 bits (66), Expect = 1.8
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 7/68 (10%)

Query: 45  TQARGSSRLLV--ASWVMQIVLGILSAVLGGF-----FYIRDYTLLVTSGAAIWTGAVAV 97
           T +  S +LL    ++V+ + L ++  V GG      F ++ Y LL+ +G     GA+  
Sbjct: 91  TVSESSRQLLTMHGTFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVT 150

Query: 98  LAGAAAFI 105
           LAG + +I
Sbjct: 151 LAGISVYI 158


>gi|87116681 lysophosphatidylcholine acyltransferase 4 [Homo
           sapiens]
          Length = 524

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 9/66 (13%)

Query: 155 SSSDWN----TPAPTQSPEE-VRRLHLCTSFMDMLKALFRTLQAMLLGVWILLLLASLTP 209
           S  DW     TP P  SP   V  LHL      + +  F  L A+L  + +LL    L  
Sbjct: 5   SPGDWAPLDPTPGPPASPNPFVHELHLSR----LQRVKFCLLGALLAPIRVLLAFIVLFL 60

Query: 210 LWLYCW 215
           LW + W
Sbjct: 61  LWPFAW 66


>gi|149944536 ichthyin protein [Homo sapiens]
          Length = 466

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 15/87 (17%)

Query: 49  GSSRLLVASWVMQIVL-GILSAVLGGFFYIRDYTLLVTSGAAIWTGAVAVLAGAAAFIYE 107
           GSS +L    ++++V  G   AV GGF Y++D        A  W G + + AG  A    
Sbjct: 133 GSSVILKKKGLLRLVATGATRAVDGGFGYLKD--------AMWWAGFLTMAAGEVA---- 180

Query: 108 KRGGTYWALLRTLLT-LAAFSTAIAAL 133
              G Y     T++T L A S  I+A+
Sbjct: 181 -NFGAYAFAPATVVTPLGALSVLISAI 206


>gi|4507035 solute carrier family 5 (sodium iodide symporter),
           member 5 [Homo sapiens]
          Length = 643

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 21/66 (31%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 82  LLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTYWALLRTLLTLAA-FSTAIAALKLWNEDF 140
           LLV++G  +W G       +A   +   GG   A L   L+L+A F +A+  L + +E +
Sbjct: 24  LLVSTGIGLWVGLARGGQRSAEDFFT--GGRRLAALPVGLSLSASFMSAVQVLGVPSEAY 81

Query: 141 RYGYSY 146
           RYG  +
Sbjct: 82  RYGLKF 87


>gi|23110997 membrane-spanning 4-domains, subfamily A, member 5
           [Homo sapiens]
          Length = 200

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 22/105 (20%), Positives = 45/105 (42%), Gaps = 12/105 (11%)

Query: 60  MQIVLGILSAVLGGFFYIR------DYTLLVTSGAAIWTGAVAVLAGAAAFIYEKRGGTY 113
           +QI+ GI++   G  F          +  +  SG   W   + + +GA     +++    
Sbjct: 53  IQILFGIMTFSFGVIFLFTLLKPYPRFPFIFLSGYPFWGSVLFINSGAFLIAVKRKTTET 112

Query: 114 WALLRTLLTLAAFSTAIAALKLW------NEDFRYGYSYYNSACR 152
             +L  ++   +   AIA + L       ++++  GYS+ NS C+
Sbjct: 113 LIILSRIMNFLSALGAIAGIILLTFGFILDQNYICGYSHQNSQCK 157


>gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 122

 Score = 28.9 bits (63), Expect = 4.0
 Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 5/54 (9%)

Query: 57  SWVMQIVLGILSAVLGGF-----FYIRDYTLLVTSGAAIWTGAVAVLAGAAAFI 105
           ++V+ + L ++  V GG      F ++ Y LL+ +G     GA+  LAG + +I
Sbjct: 4   TFVILLPLSLILMVFGGMTGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYI 57


>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
          Length = 770

 Score = 28.5 bits (62), Expect = 5.2
 Identities = 12/54 (22%), Positives = 28/54 (51%)

Query: 19  IDVHIHQESALAKLLLTCCSALRPRATQARGSSRLLVASWVMQIVLGILSAVLG 72
           +++ +H+++ +AK L T C+ + P  +Q              Q+ +  L+A++G
Sbjct: 71  LNIEMHKQTEIAKRLNTICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIG 124


>gi|215983058 magnesium transporter 1 [Homo sapiens]
          Length = 367

 Score = 28.1 bits (61), Expect = 6.8
 Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 23/90 (25%)

Query: 46  QARGSSRLLVASWVMQ-----------------IVLGILSAVLGGFFYIRDYTLLVTSGA 88
           Q RG S   +A W+                   ++LG+L AV+GG  Y+R   +      
Sbjct: 189 QVRGFSAEQIARWIADRTDVNIRVIRPPNYAGPLMLGLLLAVIGGLVYLRRSNMEFLFNK 248

Query: 89  AIWTGAVAVLAGAAAFIYEKRGGTYWALLR 118
             W  A      A  F+     G  W  +R
Sbjct: 249 TGWAFA------ALCFVLAMTSGQMWNHIR 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.134    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,543,932
Number of Sequences: 37866
Number of extensions: 323521
Number of successful extensions: 1198
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1185
Number of HSP's gapped (non-prelim): 18
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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