Guide to the Human Genome
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Search of human proteins with 31543174

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31543174 transmembrane protein 86B [Homo sapiens]
         (226 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31543174 transmembrane protein 86B [Homo sapiens]                  470   e-133
gi|23503275 transmembrane protein 86A [Homo sapiens]                  130   9e-31
gi|189083849 delta-aminolevulinic acid dehydratase [Homo sapiens]      32   0.58 
gi|4503391 dopamine receptor D5 [Homo sapiens]                         31   0.75 
gi|21704287 sialidase 4 [Homo sapiens]                                 31   0.98 
gi|170016077 ATPase type 13A1 [Homo sapiens]                           30   2.2  
gi|23510368 homeobox D11 [Homo sapiens]                                29   2.9  
gi|92859618 sphingomyelin phosphodiesterase 2, neutral [Homo sap...    28   6.4  
gi|239757134 PREDICTED: hypothetical protein [Homo sapiens]            28   8.3  
gi|169210509 PREDICTED: hypothetical protein [Homo sapiens]            28   8.3  
gi|169210005 PREDICTED: hypothetical protein [Homo sapiens]            28   8.3  
gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Hom...    28   8.3  

>gi|31543174 transmembrane protein 86B [Homo sapiens]
          Length = 226

 Score =  470 bits (1210), Expect = e-133
 Identities = 226/226 (100%), Positives = 226/226 (100%)

Query: 1   MDAGKAGQTLKTHCSAQRPDVCRWLSPFILSCCVYFCLWIPEDQLSWFAALVKCLPVLCL 60
           MDAGKAGQTLKTHCSAQRPDVCRWLSPFILSCCVYFCLWIPEDQLSWFAALVKCLPVLCL
Sbjct: 1   MDAGKAGQTLKTHCSAQRPDVCRWLSPFILSCCVYFCLWIPEDQLSWFAALVKCLPVLCL 60

Query: 61  AGFLWVMSPSGGYTQLLQGALVCSAVGDACLIWPAAFVPGMAAFATAHLLYVWAFGFSPL 120
           AGFLWVMSPSGGYTQLLQGALVCSAVGDACLIWPAAFVPGMAAFATAHLLYVWAFGFSPL
Sbjct: 61  AGFLWVMSPSGGYTQLLQGALVCSAVGDACLIWPAAFVPGMAAFATAHLLYVWAFGFSPL 120

Query: 121 QPGLLLLIILAPGPYLSLVLQHLEPDMVLPVAAYGLILMAMLWRGLAQGGSAGWGALLFT 180
           QPGLLLLIILAPGPYLSLVLQHLEPDMVLPVAAYGLILMAMLWRGLAQGGSAGWGALLFT
Sbjct: 121 QPGLLLLIILAPGPYLSLVLQHLEPDMVLPVAAYGLILMAMLWRGLAQGGSAGWGALLFT 180

Query: 181 LSDGVLAWDTFAQPLPHARLVIMTTYYAAQLLITLSALRSPVPKTD 226
           LSDGVLAWDTFAQPLPHARLVIMTTYYAAQLLITLSALRSPVPKTD
Sbjct: 181 LSDGVLAWDTFAQPLPHARLVIMTTYYAAQLLITLSALRSPVPKTD 226


>gi|23503275 transmembrane protein 86A [Homo sapiens]
          Length = 240

 Score =  130 bits (327), Expect = 9e-31
 Identities = 84/219 (38%), Positives = 117/219 (53%), Gaps = 23/219 (10%)

Query: 25  LSPFILSCCVYFCLWIPEDQLSWFAALVKCLPVLCLAGFLWVMSPSGGY-------TQLL 77
           L PF  + CVYF LW+P    SW + L+KCLP+ CL  +L++++   G+       T++ 
Sbjct: 15  LVPFFKATCVYFVLWLPSSSPSWVSTLIKCLPIFCL--WLFLLAHGLGFLLAHPSATRIF 72

Query: 78  QGALVCSAVGDACLIWP--AAFVPGMAAFATAHLLYVWAFGFSPLQPGLLLLIILAPGPY 135
            G LV SAVGDA LIW     FV G+  FA  H+ Y  AFG  PL     L++    G  
Sbjct: 73  VG-LVFSAVGDAFLIWQDQGYFVHGLLMFAVTHMFYASAFGMQPLALRTGLVMAALSGLC 131

Query: 136 LSLVLQHLEPDMVLPVAAYGLILMAMLWR---GLAQGGS--------AGWGALLFTLSDG 184
            +L+   L       V  Y  ++  M WR   GL   G+        AG GAL F +SD 
Sbjct: 132 YALLYPCLSGAFTYLVGVYVALIGFMGWRAMAGLRLAGADWRWTELAAGSGALFFIISDL 191

Query: 185 VLAWDTFAQPLPHARLVIMTTYYAAQLLITLSALRSPVP 223
            +A + F  P+P++R +IM+TYY AQ+L+ LSA+ S  P
Sbjct: 192 TIALNKFCFPVPYSRALIMSTYYVAQMLVALSAVESREP 230


>gi|189083849 delta-aminolevulinic acid dehydratase [Homo sapiens]
          Length = 330

 Score = 31.6 bits (70), Expect = 0.58
 Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 13/88 (14%)

Query: 127 LIILAPG-PYLSLVLQHLEPDMVLPVAAYGLI-LMAMLWRGLAQGGSAGWGALLFTLSDG 184
           ++++ PG PYL +V +  +    LP+A Y +    AMLW G AQ G+       F L   
Sbjct: 248 MLMVKPGMPYLDIVREVKDKHPDLPLAVYHVSGEFAMLWHG-AQAGA-------FDLKAA 299

Query: 185 VLAWDTFAQPLPHARLVIMTTYYAAQLL 212
           VL   T       A   I+ TYY  QLL
Sbjct: 300 VLEAMT---AFRRAGADIIITYYTPQLL 324


>gi|4503391 dopamine receptor D5 [Homo sapiens]
          Length = 477

 Score = 31.2 bits (69), Expect = 0.75
 Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 4/61 (6%)

Query: 5   KAGQTLKTHCSAQRPDVCRWLSPFILSCCVYFCLWIPEDQLSWFAALVKCLPVLCLAGFL 64
           K  + LKT        VC WL  FIL+C V FC   PE   + F     C+       F+
Sbjct: 290 KETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGF----PCVSETTFDVFV 345

Query: 65  W 65
           W
Sbjct: 346 W 346


>gi|21704287 sialidase 4 [Homo sapiens]
          Length = 496

 Score = 30.8 bits (68), Expect = 0.98
 Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 9/71 (12%)

Query: 127 LIILAPGP-YLSLVLQHLEPDMVLPVAAYGLILMAMLWRGLAQGGSAGWGALLFTLSDGV 185
           L+ + PGP  L+ V Q L PD      A+ L+L     RG   GGS  WGA L  L    
Sbjct: 39  LLPVPPGPTLLAFVEQRLSPD---DSHAHRLVLR----RGTLAGGSVRWGA-LHVLGTAA 90

Query: 186 LAWDTFAQPLP 196
           LA      P P
Sbjct: 91  LAEHRSMNPCP 101


>gi|170016077 ATPase type 13A1 [Homo sapiens]
          Length = 1204

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 20/89 (22%)

Query: 128 IILAPGPYLSLVLQHLEPDMVLPVAAYGLILMAMLWRGLAQGGSAGWGALLFTLSDGVLA 187
           ++ A  PY  L L  L    VLP A  GL+  A  W G A  G  GWG+          +
Sbjct: 49  LVAAVWPYRRLAL--LRRLTVLPFA--GLLYPA--WLGAAAAGCWGWGS----------S 92

Query: 188 WDTFAQPLPHARLVIMTTYYAAQLLITLS 216
           W      +P A L+++ T   A  L  LS
Sbjct: 93  W----VQIPEAALLVLATICLAHALTVLS 117


>gi|23510368 homeobox D11 [Homo sapiens]
          Length = 338

 Score = 29.3 bits (64), Expect = 2.9
 Identities = 16/43 (37%), Positives = 22/43 (51%)

Query: 134 PYLSLVLQHLEPDMVLPVAAYGLILMAMLWRGLAQGGSAGWGA 176
           PY S +  H++P   +    YGL      +RG   GGSAG G+
Sbjct: 46  PYSSNLAPHVQPVREVAFRDYGLERAKWPYRGGGGGGSAGGGS 88


>gi|92859618 sphingomyelin phosphodiesterase 2, neutral [Homo
           sapiens]
          Length = 423

 Score = 28.1 bits (61), Expect = 6.4
 Identities = 19/39 (48%), Positives = 25/39 (64%), Gaps = 2/39 (5%)

Query: 151 VAAYGLILMAMLWRGLAQGGSAGWGA-LLFTLSDGVLAW 188
           V   GL+L+A+L   LA GG AG  A LL+T S G++ W
Sbjct: 330 VIGLGLLLLALLC-VLAAGGGAGEAAILLWTPSVGLVLW 367


>gi|239757134 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 171

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 39/163 (23%), Positives = 61/163 (37%), Gaps = 22/163 (13%)

Query: 5   KAGQTLKTHCSAQRPDVCRWLSPFILSCCVYFCLW-IPEDQLSWFAALVKCLPVLCLAGF 63
           + G  + THCS Q       L   ++   +   LW +    L     LV  L    L  F
Sbjct: 7   RGGTGILTHCSLQ-------LGQLLVDLLLLRFLWKLTHCSLQPGQLLVDLL----LLRF 55

Query: 64  LWVMSPSGGYTQLLQGALVCSAVGDACL--IWPAAFVPGMAAFATAHLLYVWAFGFSPLQ 121
           LW ++    +  L  G L+   +    L  +   +  P        HL ++W      LQ
Sbjct: 56  LWKLT----HCSLQPGQLLVDLLLLRFLWKLTHCSLQPSQLLVDLLHLRFLWKLTHCSLQ 111

Query: 122 PGLLLLIILAPGPYLSLVLQHLEPDMVLPVAAYGLILMAMLWR 164
           PG LL+ +L       L    L+P  +L      L+ +  LW+
Sbjct: 112 PGQLLVDLLQLRFLWKLTHCSLQPGQLL----VDLLQLRFLWK 150


>gi|169210509 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 88

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 90  CLIWPAAFVPGMAAFATAHLLYVWAFGFSPLQPG 123
           CL+  AA +P    +   HLLY  +F  S LQ G
Sbjct: 6   CLLPVAAVLPLSGMYTRTHLLYARSFSRSSLQNG 39


>gi|169210005 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 88

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 90  CLIWPAAFVPGMAAFATAHLLYVWAFGFSPLQPG 123
           CL+  AA +P    +   HLLY  +F  S LQ G
Sbjct: 6   CLLPVAAVLPLSGMYTRTHLLYARSFSRSSLQNG 39


>gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Homo
           sapiens]
          Length = 802

 Score = 27.7 bits (60), Expect = 8.3
 Identities = 13/35 (37%), Positives = 17/35 (48%), Gaps = 4/35 (11%)

Query: 60  LAGFLWVMSPSGGYTQLLQGALVCSAVGDACLIWP 94
           L G LW +SP G  T++  G +  S  G     WP
Sbjct: 73  LQGLLWPLSPGGSDTEITSGGMRPSRAGS----WP 103


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.141    0.482 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,787,638
Number of Sequences: 37866
Number of extensions: 450299
Number of successful extensions: 1039
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1023
Number of HSP's gapped (non-prelim): 13
length of query: 226
length of database: 18,247,518
effective HSP length: 99
effective length of query: 127
effective length of database: 14,498,784
effective search space: 1841345568
effective search space used: 1841345568
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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