Guide to the Human Genome
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Search of human proteins with 31542733

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31542733 PQ loop repeat containing 1 isoform 1 [Homo
sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31542733 PQ loop repeat containing 1 isoform 1 [Homo sapiens]      549   e-156
gi|226505140 PQ loop repeat containing 1 isoform 3 [Homo sapiens]     504   e-143
gi|226503974 PQ loop repeat containing 1 isoform 2 [Homo sapiens]     229   2e-60
gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens]         34   0.15 
gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens]         34   0.15 
gi|7662022 lipin 2 [Homo sapiens]                                      30   2.2  
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...    28   8.5  
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...    28   8.5  
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...    28   8.5  

>gi|31542733 PQ loop repeat containing 1 isoform 1 [Homo sapiens]
          Length = 271

 Score =  549 bits (1414), Expect = e-156
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60
           MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA
Sbjct: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60

Query: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAADSKDEE 120
           NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAADSKDEE
Sbjct: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAADSKDEE 120

Query: 121 VKVAPRRSFLDFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL 180
           VKVAPRRSFLDFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL
Sbjct: 121 VKVAPRRSFLDFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL 180

Query: 181 TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV 240
           TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV
Sbjct: 181 TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV 240

Query: 241 DLAILGQAYAFARHPQKPAPHAVHPTGTKAL 271
           DLAILGQAYAFARHPQKPAPHAVHPTGTKAL
Sbjct: 241 DLAILGQAYAFARHPQKPAPHAVHPTGTKAL 271


>gi|226505140 PQ loop repeat containing 1 isoform 3 [Homo sapiens]
          Length = 253

 Score =  504 bits (1298), Expect = e-143
 Identities = 253/271 (93%), Positives = 253/271 (93%), Gaps = 18/271 (6%)

Query: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60
           MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA
Sbjct: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60

Query: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAADSKDEE 120
           NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFT        
Sbjct: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFT-------- 112

Query: 121 VKVAPRRSFLDFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL 180
                     DFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL
Sbjct: 113 ----------DFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL 162

Query: 181 TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV 240
           TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV
Sbjct: 163 TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV 222

Query: 241 DLAILGQAYAFARHPQKPAPHAVHPTGTKAL 271
           DLAILGQAYAFARHPQKPAPHAVHPTGTKAL
Sbjct: 223 DLAILGQAYAFARHPQKPAPHAVHPTGTKAL 253


>gi|226503974 PQ loop repeat containing 1 isoform 2 [Homo sapiens]
          Length = 132

 Score =  229 bits (584), Expect = 2e-60
 Identities = 113/114 (99%), Positives = 114/114 (100%)

Query: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60
           MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA
Sbjct: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60

Query: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAA 114
           NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTA+
Sbjct: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAS 114


>gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens]
          Length = 367

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 20/119 (16%)

Query: 146 YVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQSTEGMSIK 205
           +V  ++A  GV  ++ +L   S        ++ +    +   PQ Y N  ++STEG SI 
Sbjct: 249 FVTMIVAAVGVTTWLQFLFCFS--------YIKLAVTLVKYFPQAYMNFYYKSTEGWSIG 300

Query: 206 MVLMWTSGDAFKTAYFLLK-----------GAPLQFSVCGLLQVLVDLAILGQAYAFAR 253
            VL+  +G +F      L+           G P +F + G+  ++ D+    Q +   R
Sbjct: 301 NVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGL-GVFSIVFDVVFFIQHFCLYR 358


>gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens]
          Length = 400

 Score = 33.9 bits (76), Expect = 0.15
 Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 20/119 (16%)

Query: 146 YVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQSTEGMSIK 205
           +V  ++A  GV  ++ +L   S        ++ +    +   PQ Y N  ++STEG SI 
Sbjct: 249 FVTMIVAAVGVTTWLQFLFCFS--------YIKLAVTLVKYFPQAYMNFYYKSTEGWSIG 300

Query: 206 MVLMWTSGDAFKTAYFLLK-----------GAPLQFSVCGLLQVLVDLAILGQAYAFAR 253
            VL+  +G +F      L+           G P +F + G+  ++ D+    Q +   R
Sbjct: 301 NVLLDFTGGSFSLLQMFLQSYNNDQWTLIFGDPTKFGL-GVFSIVFDVVFFIQHFCLYR 358


>gi|7662022 lipin 2 [Homo sapiens]
          Length = 896

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 12/34 (35%), Positives = 16/34 (47%)

Query: 112 TAADSKDEEVKVAPRRSFLDFDPHHFWQWSSFSD 145
           TA    D E++V P  S L  + H  W W  F +
Sbjct: 238 TACPKSDSELEVKPAESLLRSESHMEWTWGGFPE 271


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 18/48 (37%), Positives = 24/48 (50%)

Query: 143 FSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQL 190
           F DY   VLAF  V G +++L    A F E L     L E  + +P+L
Sbjct: 394 FLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRL 441


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 18/48 (37%), Positives = 24/48 (50%)

Query: 143 FSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQL 190
           F DY   VLAF  V G +++L    A F E L     L E  + +P+L
Sbjct: 394 FLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRL 441


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 18/48 (37%), Positives = 24/48 (50%)

Query: 143 FSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQL 190
           F DY   VLAF  V G +++L    A F E L     L E  + +P+L
Sbjct: 394 FLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRL 441


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.138    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,632,207
Number of Sequences: 37866
Number of extensions: 376088
Number of successful extensions: 904
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 892
Number of HSP's gapped (non-prelim): 11
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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