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Search of human proteins with 12232423
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12232423 inositol 1,3,4,5,6-pentakisphosphate 2-kinase [Homo
sapiens]
(491 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12232423 inositol 1,3,4,5,6-pentakisphosphate 2-kinase [Homo ... 1009 0.0
gi|5174473 intracisternal A particle-promoted polypeptide isofor... 37 0.053
gi|223890235 intracisternal A particle-promoted polypeptide isof... 37 0.053
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 32 1.3
gi|13899303 cysteine-rich secretory protein LCCL domain containi... 32 1.3
gi|4507975 zinc finger protein 345 [Homo sapiens] 32 1.3
gi|39930351 dynamin binding protein [Homo sapiens] 32 1.7
gi|150170718 zinc finger protein 292 [Homo sapiens] 32 1.7
gi|223029412 otoconin 90 [Homo sapiens] 30 3.8
gi|229577396 zinc finger protein 583 [Homo sapiens] 30 5.0
gi|229577249 zinc finger protein 583 [Homo sapiens] 30 5.0
gi|229577247 zinc finger protein 583 [Homo sapiens] 30 5.0
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 30 6.5
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 30 6.5
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 30 6.5
gi|157694497 zinc finger and BTB domain containing 10 isoform b ... 29 8.5
gi|157694499 zinc finger and BTB domain containing 10 isoform a ... 29 8.5
>gi|12232423 inositol 1,3,4,5,6-pentakisphosphate 2-kinase [Homo
sapiens]
Length = 491
Score = 1009 bits (2608), Expect = 0.0
Identities = 491/491 (100%), Positives = 491/491 (100%)
Query: 1 MEEGKMDENEWGYHGEGNKSLVVAHAQRCVVLRFLKFPPNRKKTSEEIFQHLQNIVDFGK 60
MEEGKMDENEWGYHGEGNKSLVVAHAQRCVVLRFLKFPPNRKKTSEEIFQHLQNIVDFGK
Sbjct: 1 MEEGKMDENEWGYHGEGNKSLVVAHAQRCVVLRFLKFPPNRKKTSEEIFQHLQNIVDFGK 60
Query: 61 NVMKEFLGENYVHYGEVVQLPLEFVKQLCLKIQSERPESRCDKDLDTLSGYAMCLPNLTR 120
NVMKEFLGENYVHYGEVVQLPLEFVKQLCLKIQSERPESRCDKDLDTLSGYAMCLPNLTR
Sbjct: 61 NVMKEFLGENYVHYGEVVQLPLEFVKQLCLKIQSERPESRCDKDLDTLSGYAMCLPNLTR 120
Query: 121 LQTYRFAEHRPILCVEIKPKCGFIPFSSDVTHEMKHKVCRYCMHQHLKVATGKWKQISKY 180
LQTYRFAEHRPILCVEIKPKCGFIPFSSDVTHEMKHKVCRYCMHQHLKVATGKWKQISKY
Sbjct: 121 LQTYRFAEHRPILCVEIKPKCGFIPFSSDVTHEMKHKVCRYCMHQHLKVATGKWKQISKY 180
Query: 181 CPLDLYSGNKQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVADWSELAHHLKPF 240
CPLDLYSGNKQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVADWSELAHHLKPF
Sbjct: 181 CPLDLYSGNKQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVADWSELAHHLKPF 240
Query: 241 FFPSNGLASGPHCTRAVIRELVHVITRVLLSGSDKGRAGTLSPGLGPQGPRVCEASPFSR 300
FFPSNGLASGPHCTRAVIRELVHVITRVLLSGSDKGRAGTLSPGLGPQGPRVCEASPFSR
Sbjct: 241 FFPSNGLASGPHCTRAVIRELVHVITRVLLSGSDKGRAGTLSPGLGPQGPRVCEASPFSR 300
Query: 301 SLRCQGKNTPERSGLPKGCLLYKTLQVQMLDLLDIEGLYPLYNRVERYLEEFPEERKTLQ 360
SLRCQGKNTPERSGLPKGCLLYKTLQVQMLDLLDIEGLYPLYNRVERYLEEFPEERKTLQ
Sbjct: 301 SLRCQGKNTPERSGLPKGCLLYKTLQVQMLDLLDIEGLYPLYNRVERYLEEFPEERKTLQ 360
Query: 361 IDGPYDEAFYQKLLDLSTEDDGTVAFALTKVQQYRVAMTAKDCSIMIALSPCLQDASSDQ 420
IDGPYDEAFYQKLLDLSTEDDGTVAFALTKVQQYRVAMTAKDCSIMIALSPCLQDASSDQ
Sbjct: 361 IDGPYDEAFYQKLLDLSTEDDGTVAFALTKVQQYRVAMTAKDCSIMIALSPCLQDASSDQ 420
Query: 421 RPVVPSSRSRFAFSVSVLDLDLKPYESIPHQYKLDGKIVNYYSKTVRAKDNAVMSTRFKE 480
RPVVPSSRSRFAFSVSVLDLDLKPYESIPHQYKLDGKIVNYYSKTVRAKDNAVMSTRFKE
Sbjct: 421 RPVVPSSRSRFAFSVSVLDLDLKPYESIPHQYKLDGKIVNYYSKTVRAKDNAVMSTRFKE 480
Query: 481 SEDCTLVLHKV 491
SEDCTLVLHKV
Sbjct: 481 SEDCTLVLHKV 491
>gi|5174473 intracisternal A particle-promoted polypeptide isoform 1
[Homo sapiens]
Length = 584
Score = 36.6 bits (83), Expect = 0.053
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 16/105 (15%)
Query: 32 LRFLKFPPNRKKTSEEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLCLK 91
+RF PP R + ++++ + DF V + L + Y EV + P E L+
Sbjct: 226 IRFPLLPPQR------LLKYIEGVSDFNLRVALQTLLKEYC---EVCKSPKENKFCSFLQ 276
Query: 92 IQSERPESRCDKDLDTLSGYAMCLPNLTRLQTYRFAEHRPILCVE 136
RP + K L + GY TRLQ R+++ R + CVE
Sbjct: 277 TSKVRPRKKARKYLYAVGGY-------TRLQGGRWSDSRALSCVE 314
>gi|223890235 intracisternal A particle-promoted polypeptide isoform
2 [Homo sapiens]
Length = 582
Score = 36.6 bits (83), Expect = 0.053
Identities = 30/105 (28%), Positives = 47/105 (44%), Gaps = 16/105 (15%)
Query: 32 LRFLKFPPNRKKTSEEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLCLK 91
+RF PP R + ++++ + DF V + L + Y EV + P E L+
Sbjct: 226 IRFPLLPPQR------LLKYIEGVSDFNLRVALQTLLKEYC---EVCKSPKENKFCSFLQ 276
Query: 92 IQSERPESRCDKDLDTLSGYAMCLPNLTRLQTYRFAEHRPILCVE 136
RP + K L + GY TRLQ R+++ R + CVE
Sbjct: 277 TSKVRPRKKARKYLYAVGGY-------TRLQGGRWSDSRALSCVE 314
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 32.0 bits (71), Expect = 1.3
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 2/84 (2%)
Query: 136 EIKPKCGFIPFSSDVTHEMKHKVCRYCMHQHLKVATGKWKQISKYCPLDLYSGNKQRMHF 195
E PK IPF+S ++M + H+ + G ++I ++C L +G + M+
Sbjct: 480 EKNPKVAEIPFNSTNKYQMSIHLREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSMND 539
Query: 196 ALKSLLQEAQNNLKIFKNGELIYG 219
+K Q A L++ GE + G
Sbjct: 540 EMKEAFQNAY--LELGGLGERVLG 561
>gi|13899303 cysteine-rich secretory protein LCCL domain containing
1 [Homo sapiens]
Length = 500
Score = 32.0 bits (71), Expect = 1.3
Identities = 27/135 (20%), Positives = 51/135 (37%), Gaps = 23/135 (17%)
Query: 131 PILCVEIKPKCGFIPFSSDVTHEMKHKVCRYCMHQHLKVATGKWKQISKYCPLDLYSGNK 190
P C++ K K V +EM+ +CR +H + G W I++ +
Sbjct: 314 PAGCLDSKAKV-----IGSVHYEMQSSICRAAIHYGIIDNDGGWVDITR----------Q 358
Query: 191 QRMHFALKSLLQ--------EAQNNLKIFKNGELIYGCKDARSPVADWSELAHHLKPFFF 242
R H+ +KS ++ N+ + K C+ + + + A H +
Sbjct: 359 GRKHYFIKSNRNGIQTIGKYQSANSFTVSKVTVQAVTCETTVEQLCPFHKPASHCPRVYC 418
Query: 243 PSNGLASGPHCTRAV 257
P N + + PH R +
Sbjct: 419 PRNCMQANPHYARVI 433
>gi|4507975 zinc finger protein 345 [Homo sapiens]
Length = 488
Score = 32.0 bits (71), Expect = 1.3
Identities = 46/172 (26%), Positives = 65/172 (37%), Gaps = 50/172 (29%)
Query: 118 LTRLQTYRFAEHRPILCVEIKPKCG-FIPFSSDVT-HEMKHK-----VCRYC-------- 162
LTR Q E +P +C E CG F S +T H+ H VC+ C
Sbjct: 245 LTRHQRIHTGE-KPYICNE----CGKAFSFGSALTRHQRIHTGEKPYVCKECGKAFNSGS 299
Query: 163 -MHQHLKVATGKWKQISKYCPLDLYSGNK----QRMHFALKSLLQEAQNNLKIFKNGELI 217
+ QH ++ TG+ K C SG+K QRMH GE
Sbjct: 300 DLTQHQRIHTGEKPYECKECEKAFRSGSKLIQHQRMH------------------TGEKP 341
Query: 218 YGCKDARSPVADWSELAHH------LKPFFFPSNGLASGPHCTRAVIRELVH 263
Y CK+ + S+L H KP+ G A G ++ + +L+H
Sbjct: 342 YECKECGKTFSSGSDLTQHHRIHTGEKPYECKECGKAFGSG-SKLIQHQLIH 392
>gi|39930351 dynamin binding protein [Homo sapiens]
Length = 1577
Score = 31.6 bits (70), Expect = 1.7
Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 1/73 (1%)
Query: 43 KTSEEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLCLKIQSERPESRCD 102
K S + HL+++ F + E E ++ +L F++ L L +Q R ES C
Sbjct: 999 KKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIR-ESACV 1057
Query: 103 KDLDTLSGYAMCL 115
K + +S + +C+
Sbjct: 1058 KVVAAVSMWDVCM 1070
Score = 29.3 bits (64), Expect = 8.5
Identities = 18/61 (29%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
Query: 46 EEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQ---LCLKIQSERPESRCD 102
E+I +HLQ+ + K++ E+ NY++ G + P++ V + L +++ + PES D
Sbjct: 887 EKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPD 946
Query: 103 K 103
K
Sbjct: 947 K 947
>gi|150170718 zinc finger protein 292 [Homo sapiens]
Length = 2723
Score = 31.6 bits (70), Expect = 1.7
Identities = 11/31 (35%), Positives = 21/31 (67%)
Query: 130 RPILCVEIKPKCGFIPFSSDVTHEMKHKVCR 160
+P +C+++K K GF ++ +TH +H+V R
Sbjct: 748 KPYICIQMKCKAGFNSYAELLTHRKEHQVFR 778
>gi|223029412 otoconin 90 [Homo sapiens]
Length = 477
Score = 30.4 bits (67), Expect = 3.8
Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 2/63 (3%)
Query: 81 PLEFVKQLCLKIQSERPESRCDKDLDTLSGYAMCLPNLTRLQTY-RFAEHRPILCVEIKP 139
P EF C Q R E R D D LS + CL + RL P++CV+ P
Sbjct: 320 PEEFESYGCYCGQEGRGEPRDDLDRCCLSHHC-CLEQVRRLGCLLERLPWSPVVCVDHTP 378
Query: 140 KCG 142
KCG
Sbjct: 379 KCG 381
>gi|229577396 zinc finger protein 583 [Homo sapiens]
Length = 569
Score = 30.0 bits (66), Expect = 5.0
Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 42/127 (33%)
Query: 130 RPILCVEIKPKCG--FIPFSSDVTHEMKHK-----VCRYC---------MHQHLKVATGK 173
+P C+E CG F SS H+ H +C+ C + QH ++ TG+
Sbjct: 434 KPYECIE----CGKAFSNSSSLAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGE 489
Query: 174 WKQISKYCPLDL-YSGN---KQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVAD 229
C YSG+ QR+H GE Y CKD R
Sbjct: 490 KPYECNVCGKAFSYSGSLTLHQRIH------------------TGERPYECKDCRKSFRQ 531
Query: 230 WSELAHH 236
+ LAHH
Sbjct: 532 RAHLAHH 538
>gi|229577249 zinc finger protein 583 [Homo sapiens]
Length = 569
Score = 30.0 bits (66), Expect = 5.0
Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 42/127 (33%)
Query: 130 RPILCVEIKPKCG--FIPFSSDVTHEMKHK-----VCRYC---------MHQHLKVATGK 173
+P C+E CG F SS H+ H +C+ C + QH ++ TG+
Sbjct: 434 KPYECIE----CGKAFSNSSSLAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGE 489
Query: 174 WKQISKYCPLDL-YSGN---KQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVAD 229
C YSG+ QR+H GE Y CKD R
Sbjct: 490 KPYECNVCGKAFSYSGSLTLHQRIH------------------TGERPYECKDCRKSFRQ 531
Query: 230 WSELAHH 236
+ LAHH
Sbjct: 532 RAHLAHH 538
>gi|229577247 zinc finger protein 583 [Homo sapiens]
Length = 569
Score = 30.0 bits (66), Expect = 5.0
Identities = 34/127 (26%), Positives = 46/127 (36%), Gaps = 42/127 (33%)
Query: 130 RPILCVEIKPKCG--FIPFSSDVTHEMKHK-----VCRYC---------MHQHLKVATGK 173
+P C+E CG F SS H+ H +C+ C + QH ++ TG+
Sbjct: 434 KPYECIE----CGKAFSNSSSLAQHQRSHTGEKPYMCKECRKTFSQNAGLAQHQRIHTGE 489
Query: 174 WKQISKYCPLDL-YSGN---KQRMHFALKSLLQEAQNNLKIFKNGELIYGCKDARSPVAD 229
C YSG+ QR+H GE Y CKD R
Sbjct: 490 KPYECNVCGKAFSYSGSLTLHQRIH------------------TGERPYECKDCRKSFRQ 531
Query: 230 WSELAHH 236
+ LAHH
Sbjct: 532 RAHLAHH 538
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 29.6 bits (65), Expect = 6.5
Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 5/44 (11%)
Query: 46 EEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLC 89
++ F +++ + G V K F+G+N +G PLE V++LC
Sbjct: 38 QQFFVVMEHCLKHGLKVKKSFIGQNKSFFG-----PLELVEKLC 76
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 29.6 bits (65), Expect = 6.5
Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 5/44 (11%)
Query: 46 EEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLC 89
++ F +++ + G V K F+G+N +G PLE V++LC
Sbjct: 38 QQFFVVMEHCLKHGLKVKKSFIGQNKSFFG-----PLELVEKLC 76
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 29.6 bits (65), Expect = 6.5
Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 5/44 (11%)
Query: 46 EEIFQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQLC 89
++ F +++ + G V K F+G+N +G PLE V++LC
Sbjct: 146 QQFFVVMEHCLKHGLKVKKSFIGQNKSFFG-----PLELVEKLC 184
>gi|157694497 zinc finger and BTB domain containing 10 isoform b
[Homo sapiens]
Length = 847
Score = 29.3 bits (64), Expect = 8.5
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 49 FQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQ-LCLKIQSERPES 99
F + N+V +N ++ +Y+ EVVQ F+K L + I+SE PES
Sbjct: 423 FLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPES 474
>gi|157694499 zinc finger and BTB domain containing 10 isoform a
[Homo sapiens]
Length = 871
Score = 29.3 bits (64), Expect = 8.5
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 49 FQHLQNIVDFGKNVMKEFLGENYVHYGEVVQLPLEFVKQ-LCLKIQSERPES 99
F + N+V +N ++ +Y+ EVVQ F+K L + I+SE PES
Sbjct: 423 FLYSGNLVLTSQNAIEVMTVASYLQMSEVVQTCRNFIKDALNISIKSEAPES 474
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,706,849
Number of Sequences: 37866
Number of extensions: 911143
Number of successful extensions: 2383
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 2369
Number of HSP's gapped (non-prelim): 26
length of query: 491
length of database: 18,247,518
effective HSP length: 106
effective length of query: 385
effective length of database: 14,233,722
effective search space: 5479982970
effective search space used: 5479982970
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.