Search of human proteins with 29294631

Search of human proteins with 29294631

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29294631 purinergic receptor P2X7 [Homo sapiens]
         (595 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29294631 purinergic receptor P2X7 [Homo sapiens]                  1259   0.0  
gi|28416927 purinergic receptor P2X4 [Homo sapiens]                   333   3e-91
gi|4505545 purinergic receptor P2X1 [Homo sapiens]                    292   7e-79
gi|28416925 purinergic receptor P2X3 [Homo sapiens]                   255   7e-68
gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]         241   1e-63
gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]         241   2e-63
gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]         235   1e-61
gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]        229   5e-60
gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]        224   2e-58
gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]         219   7e-57
gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]          218   1e-56
gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]         203   4e-52
gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]         194   3e-49
gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]         188   1e-47
gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]          87   6e-17
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is...    38   0.023
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ...    38   0.023
gi|13994364 keratin associated protein 3.2 [Homo sapiens]              36   0.088
gi|15055511 keratin associated protein 3-3 [Homo sapiens]              35   0.20 
gi|13994362 keratin associated protein 3.1 [Homo sapiens]              35   0.20 
gi|224493895 t-complex 11 (mouse) like 1 [Homo sapiens]                30   4.8  
gi|224493847 t-complex 11 (mouse) like 1 [Homo sapiens]                30   4.8  
gi|24497497 solute carrier family 22 member 7 isoform a [Homo sa...    30   6.3  
gi|110347431 latent transforming growth factor beta binding prot...    30   6.3  

>gi|29294631 purinergic receptor P2X7 [Homo sapiens]
          Length = 595

 Score = 1259 bits (3257), Expect = 0.0
 Identities = 595/595 (100%), Positives = 595/595 (100%)

Query: 1   MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS 60
           MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS
Sbjct: 1   MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS 60

Query: 61  VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP 120
           VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP
Sbjct: 61  VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP 120

Query: 121 EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPA 180
           EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPA
Sbjct: 121 EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPA 180

Query: 181 LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD 240
           LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD
Sbjct: 181 LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD 240

Query: 241 NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK 300
           NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK
Sbjct: 241 NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK 300

Query: 301 ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS 360
           ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS
Sbjct: 301 ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS 360

Query: 361 NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS 420
           NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS
Sbjct: 361 NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS 420

Query: 421 LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG 480
           LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG
Sbjct: 421 LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG 480

Query: 481 SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS 540
           SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS
Sbjct: 481 SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS 540

Query: 541 TNSRLRHCAYRCYATWRFGSQDMADFANLPSCCRWRIRKEFPKSEGQYSGFKSPY 595
           TNSRLRHCAYRCYATWRFGSQDMADFANLPSCCRWRIRKEFPKSEGQYSGFKSPY
Sbjct: 541 TNSRLRHCAYRCYATWRFGSQDMADFANLPSCCRWRIRKEFPKSEGQYSGFKSPY 595


>gi|28416927 purinergic receptor P2X4 [Homo sapiens]
          Length = 388

 Score =  333 bits (854), Expect = 3e-91
 Identities = 178/402 (44%), Positives = 239/402 (59%), Gaps = 35/402 (8%)

Query: 1   MPACCSC--SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVC-FALVSDKLYQRKEPV 57
           M  CC+   + +F+Y+T ++  I+S   G +     ++I +YV  +  V +K YQ  + V
Sbjct: 1   MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV 60

Query: 58  ISSVHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQ 116
           +SSV TKVKG+A            KL   ++D ADY  P Q  NS FVMTN + T  Q Q
Sbjct: 61  VSSVTTKVKGVAVTN-------TSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQ 113

Query: 117 RLCPEYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEA 176
            LCPE P   T+C SD  C  G     S G+ TGRCV + G+ KTCEV+AWCP+E     
Sbjct: 114 GLCPEIPDATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHV 173

Query: 177 PRPALLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNIT----CTFHKTQNPQCPIFRLG 232
           P+PA L +AENFT+L+KNNI +P  N++ RNILP +  T    C +    +P CPIFRLG
Sbjct: 174 PQPAFLKAAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLG 233

Query: 233 DIFRETGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYN 292
            I    G +F D+A++GGIMGI++ WDCNLDR    C P+YSFRRLD +    ++ PGYN
Sbjct: 234 KIVENAGHSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYN 293

Query: 293 FRYAKYYKE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFI 351
           FR+AKYY++    E+RTLIK +GIRFDI+VFG  GKFDII  ++ IGS L+  G+A V  
Sbjct: 294 FRFAKYYRDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLC 353

Query: 352 DFLIDTYSSNCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVE 393
           D ++           +Y        C+    YYR+K    VE
Sbjct: 354 DIIV-----------LY--------CMKKRLYYREKKYKYVE 376


>gi|4505545 purinergic receptor P2X1 [Homo sapiens]
          Length = 399

 Score =  292 bits (747), Expect = 7e-79
 Identities = 153/352 (43%), Positives = 214/352 (60%), Gaps = 17/352 (4%)

Query: 10  VFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVC-FALVSDKLYQRKEPVISSVHTKVKGI 68
           +F+Y+T ++  +++   G I     +++  YV  +  + +K YQ    +ISSV  K+KG+
Sbjct: 13  LFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSGLISSVSVKLKGL 72

Query: 69  AEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQRLCPEYPTRRT 127
           A  +       +  L   V+D ADY FP QG NSF VMTNF+ T  Q Q  C E+P    
Sbjct: 73  AVTQ-------LPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEHP-EGG 124

Query: 128 LCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPALLNSAEN 187
           +C  D GC  G    +++GI+TG+CV +    KTCE+  WCP+E  ++ PRPALL  AEN
Sbjct: 125 ICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLREAEN 184

Query: 188 FTVLIKNNIDFPGHNYTTRNILPGLNI----TCTFHKTQNPQCPIFRLGDIFRETGDNFS 243
           FT+ IKN+I FP      RN++  +N     TC FHKT +P CP+F+LG + +E+G NFS
Sbjct: 185 FTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESGQNFS 244

Query: 244 DVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKENN 303
            +A +GG++GI I W C+LD    HCRP Y F  L ++    +L PG+NFR+A+++ EN 
Sbjct: 245 TLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEK---NLSPGFNFRFARHFVENG 301

Query: 304 VEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI 355
              R L KVFGIRFDILV G  GKFDII  +  IGS +  FG+A V  D L+
Sbjct: 302 TNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLL 353


>gi|28416925 purinergic receptor P2X3 [Homo sapiens]
          Length = 397

 Score =  255 bits (652), Expect = 7e-68
 Identities = 151/356 (42%), Positives = 204/356 (57%), Gaps = 25/356 (7%)

Query: 8   SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEPVI-SSVHTKV 65
           SD F YET K   ++S   G I     ++I SY V +  + +K YQ ++  I SSV TKV
Sbjct: 5   SDFFTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIESSVVTKV 64

Query: 66  KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVM-TNFLKTEGQEQRLCPEYPT 124
           KG          +G+    + V D +DY  P QG S FV+ T  + TE Q Q  CPE   
Sbjct: 65  KG----------SGL--YANRVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGFCPE-SE 111

Query: 125 RRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPALLNS 184
            +  C SD  C  G       GI TGRCV Y    +TCE+  WCP E V+    P ++  
Sbjct: 112 EKYRCVSDSQC--GPERLPGGGILTGRCVNYSSVLRTCEIQGWCPTE-VDTVETPIMME- 167

Query: 185 AENFTVLIKNNIDFPGHNYTTRNILPGLNI----TCTFHKTQNPQCPIFRLGDIFRETGD 240
           AENFT+ IKN+I FP  N+   N+LP L      TC FH  ++P CPI R+GD+ +  G 
Sbjct: 168 AENFTIFIKNSIRFPLFNFEKGNLLPNLTARDMKTCRFHPDKDPFCPILRVGDVVKFAGQ 227

Query: 241 NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK 300
           +F+ +A  GG++GI+I W C+LD+ +  C PKYSF RLD  +   S+ PGYNFR+AKYYK
Sbjct: 228 DFAKLARTGGVLGIKIGWVCDLDKAWDQCIPKYSFTRLDSVSEKSSVSPGYNFRFAKYYK 287

Query: 301 -ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI 355
            EN  E RTL+K FGIRFD+LV+G  GKF+II  ++   +  +  G+  V  D ++
Sbjct: 288 MENGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIIL 343


>gi|25092719 purinergic receptor P2X2 isoform A [Homo sapiens]
          Length = 471

 Score =  241 bits (616), Expect = 1e-63
 Identities = 145/378 (38%), Positives = 207/378 (54%), Gaps = 25/378 (6%)

Query: 8   SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEP-VISSVHTKV 65
           S ++ YET KV  +++   G +     ++I  Y V +  +  K YQ  E    SS+ TKV
Sbjct: 23  SALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKV 82

Query: 66  KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFF-VMTNFLKTEGQEQRLCPE-YP 123
           KGI   +            H V+D  +Y  P +G S F ++T    T  Q Q  CPE   
Sbjct: 83  KGITTSE------------HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIR 130

Query: 124 TRRTLCSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALL 182
                C SD  C  G +D    G++TGRCV  Y+G  KTCEV  WCP+E      +  L 
Sbjct: 131 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLG 189

Query: 183 NSAENFTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETG 239
             A NFT+LIKN+I +P  +++  NI     G    CTFH+  +  CPIF+LG I  + G
Sbjct: 190 TMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAG 249

Query: 240 DNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYY 299
           ++F+++A +GG++G+ I WDC+LD     C PKYSFRRLD K  +V    GYNFR+AKYY
Sbjct: 250 ESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYY 307

Query: 300 KENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY- 358
           K N    RTLIK +GIR D++V G  GKF +I  ++ + + L+  G+ +   D+++ T+ 
Sbjct: 308 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM 367

Query: 359 SSNCCRSHIYPWCKCCQP 376
           + N   SH   + K C P
Sbjct: 368 NKNKVYSH-KKFDKVCTP 384


>gi|28416923 purinergic receptor P2X2 isoform B [Homo sapiens]
          Length = 404

 Score =  241 bits (614), Expect = 2e-63
 Identities = 142/368 (38%), Positives = 203/368 (55%), Gaps = 24/368 (6%)

Query: 8   SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEP-VISSVHTKV 65
           S ++ YET KV  +++   G +     ++I  Y V +  +  K YQ  E    SS+ TKV
Sbjct: 23  SALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKV 82

Query: 66  KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFF-VMTNFLKTEGQEQRLCPE-YP 123
           KGI   +            H V+D  +Y  P +G S F ++T    T  Q Q  CPE   
Sbjct: 83  KGITTSE------------HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIR 130

Query: 124 TRRTLCSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALL 182
                C SD  C  G +D    G++TGRCV  Y+G  KTCEV  WCP+E      +  L 
Sbjct: 131 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLG 189

Query: 183 NSAENFTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETG 239
             A NFT+LIKN+I +P  +++  NI     G    CTFH+  +  CPIF+LG I  + G
Sbjct: 190 TMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAG 249

Query: 240 DNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYY 299
           ++F+++A +GG++G+ I WDC+LD     C PKYSFRRLD K  +V    GYNFR+AKYY
Sbjct: 250 ESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYY 307

Query: 300 KENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY- 358
           K N    RTLIK +GIR D++V G  GKF +I  ++ + + L+  G+ +   D+++ T+ 
Sbjct: 308 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFM 367

Query: 359 SSNCCRSH 366
           + N   SH
Sbjct: 368 NKNKVYSH 375


>gi|25092733 purinergic receptor P2X2 isoform D [Homo sapiens]
          Length = 497

 Score =  235 bits (599), Expect = 1e-61
 Identities = 137/347 (39%), Positives = 192/347 (55%), Gaps = 23/347 (6%)

Query: 8   SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEP-VISSVHTKV 65
           S ++ YET KV  +++   G +     ++I  Y V +  +  K YQ  E    SS+ TKV
Sbjct: 23  SALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKV 82

Query: 66  KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFF-VMTNFLKTEGQEQRLCPE-YP 123
           KGI   +            H V+D  +Y  P +G S F ++T    T  Q Q  CPE   
Sbjct: 83  KGITTSE------------HKVWDVEEYVKPPEGGSVFSIITRVEATHSQTQGTCPESIR 130

Query: 124 TRRTLCSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALL 182
                C SD  C  G +D    G++TGRCV  Y+G  KTCEV  WCP+E      +  L 
Sbjct: 131 VHNATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLG 189

Query: 183 NSAENFTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETG 239
             A NFT+LIKN+I +P  +++  NI     G    CTFH+  +  CPIF+LG I  + G
Sbjct: 190 TMAPNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAG 249

Query: 240 DNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYY 299
           ++F+++A +GG++G+ I WDC+LD     C PKYSFRRLD K  +V    GYNFR+AKYY
Sbjct: 250 ESFTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYY 307

Query: 300 KENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGL 346
           K N    RTLIK +GIR D++V G  GKF +I  ++ + + L+  G+
Sbjct: 308 KINGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGV 354


>gi|157419148 purinergic receptor P2X6 isoform 1 [Homo sapiens]
          Length = 441

 Score =  229 bits (584), Expect = 5e-60
 Identities = 135/356 (37%), Positives = 203/356 (57%), Gaps = 28/356 (7%)

Query: 10  VFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVC-FALVSDKLYQRK--EPVISSVHTKVK 66
           +  Y+T K    ++   G ++      I  YV  +AL++ K YQ +  EP  S + TK+K
Sbjct: 22  LLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLAKKGYQERDLEPQFSII-TKLK 80

Query: 67  GIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQRLCPEYPTR 125
           G++  +       +K+L + ++D AD+  P QG N FF++TNFL T  Q Q  CPE+P+ 
Sbjct: 81  GVSVTQ-------IKELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSV 133

Query: 126 RTL-CSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPALLNS 184
               C  D  C +G     S G++TG+CVV+ G  +TCE+ +WCP+E+     RP LL  
Sbjct: 134 PLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVESGVVPSRP-LLAQ 192

Query: 185 AENFTVLIKNNIDFPGHNYTTRNILPGLNIT----CTFHKTQNPQCPIFRLGDIFRETGD 240
           A+NFT+ IKN + F   N++  N L   + T    C +    +P CP+FR+GD+  + G 
Sbjct: 193 AQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGG 252

Query: 241 NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK 300
            F D+A+ GG +GI ++WDC+LD     C P YSF +L +K+        YNFR A ++ 
Sbjct: 253 TFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSF-QLQEKS--------YNFRTATHWW 303

Query: 301 EN-NVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI 355
           E   VE RTL+K++GIRFDILV G  GKF +I   V +G+  ++ G+   F D L+
Sbjct: 304 EQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLL 359


>gi|227116341 purinergic receptor P2X6 isoform 2 [Homo sapiens]
          Length = 415

 Score =  224 bits (570), Expect = 2e-58
 Identities = 132/341 (38%), Positives = 195/341 (57%), Gaps = 39/341 (11%)

Query: 24  MNYGTIKWFFHVIIFSYVCFALVSDKLYQRK--EPVISSVHTKVKGIAEVKEEIVENGVK 81
           ++Y T KW            AL++ K YQ +  EP  S + TK+KG++  +       +K
Sbjct: 23  LDYKTEKW------------ALLAKKGYQERDLEPQFSII-TKLKGVSVTQ-------IK 62

Query: 82  KLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQRLCPEYPTRRTL-CSSDRGCKKGW 139
           +L + ++D AD+  P QG N FF++TNFL T  Q Q  CPE+P+     C  D  C +G 
Sbjct: 63  ELGNRLWDVADFVKPPQGENVFFLVTNFLVTPAQVQGRCPEHPSVPLANCWVDEDCPEGE 122

Query: 140 MDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPALLNSAENFTVLIKNNIDFP 199
               S G++TG+CVV+ G  +TCE+ +WCP+E+     RP LL  A+NFT+ IKN + F 
Sbjct: 123 GGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVESGVVPSRP-LLAQAQNFTLFIKNTVTFS 181

Query: 200 GHNYTTRNILPGLNIT----CTFHKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIMGIE 255
             N++  N L   + T    C +    +P CP+FR+GD+  + G  F D+A+ GG +GI 
Sbjct: 182 KFNFSKSNALETWDPTYFKHCRYEPQFSPYCPVFRIGDLVAKAGGTFEDLALLGGSVGIR 241

Query: 256 IYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKEN-NVEKRTLIKVFG 314
           ++WDC+LD     C P YSF +L +K+        YNFR A ++ E   VE RTL+K++G
Sbjct: 242 VHWDCDLDTGDSGCWPHYSF-QLQEKS--------YNFRTATHWWEQPGVEARTLLKLYG 292

Query: 315 IRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLI 355
           IRFDILV G  GKF +I   V +G+  ++ G+   F D L+
Sbjct: 293 IRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLL 333


>gi|28416933 purinergic receptor P2X5 isoform A [Homo sapiens]
          Length = 422

 Score =  219 bits (557), Expect = 7e-57
 Identities = 131/341 (38%), Positives = 186/341 (54%), Gaps = 20/341 (5%)

Query: 7   CSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEPVI-SSVHTK 64
           C  +F Y+T K    ++   G +       I +Y V +  +  K YQ  +  + S+V TK
Sbjct: 10  CLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITK 69

Query: 65  VKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQRLCPEYP 123
           VKG+A             L   ++D ADY  P QG N FFV+TN + T  Q Q +C E  
Sbjct: 70  VKGVAFTN-------TSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENE 122

Query: 124 -TRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQK-TCEVSAWCPIEAVEEAPRPAL 181
                 CS D  C  G       G++TGRC+  E   + TCE+ AWCP+E     P    
Sbjct: 123 GIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLET-SSRPEEPF 181

Query: 182 LNSAENFTVLIKNNIDFPGHNYTTRNILP----GLNITCTFHKTQNPQCPIFRLGDIFRE 237
           L  AE+FT+ IKN+I FP  N++  N++         +C F   +N  CPIFRLG + R 
Sbjct: 182 LKEAEDFTIFIKNHIRFPKFNFSKSNVMDVKDRSFLKSCHFGP-KNHYCPIFRLGSVIRW 240

Query: 238 TGDNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAK 297
            G +F D+A++GG++GI I W+C+LD+    C P YSF RLD+K +  S+  GYNFR+A+
Sbjct: 241 AGSDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK-SVSSGYNFRFAR 299

Query: 298 YYKE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYI 337
           YY++   VE RTL+K +GIRFD++V G G  F  + L+  I
Sbjct: 300 YYRDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLI 340


>gi|7706629 purinergic receptor P2X2 isoform C [Homo sapiens]
          Length = 447

 Score =  218 bits (556), Expect = 1e-56
 Identities = 135/376 (35%), Positives = 195/376 (51%), Gaps = 45/376 (11%)

Query: 8   SDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEP-VISSVHTKV 65
           S ++ YET KV  +++   G +     ++I  Y V +  +  K YQ  E    SS+ TKV
Sbjct: 23  SALWDYETPKVIVVRNRRLGVLYRAVQLLILLYFVWYVFIVQKSYQESETGPESSIITKV 82

Query: 66  KGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCPEYPTR 125
           KGI   +            H V+D  +Y  P +                           
Sbjct: 83  KGITTSE------------HKVWDVEEYVKPPES----------------------IRVH 108

Query: 126 RTLCSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALLNS 184
              C SD  C  G +D    G++TGRCV  Y+G  KTCEV  WCP+E      +  L   
Sbjct: 109 NATCLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLGTM 167

Query: 185 AENFTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETGDN 241
           A NFT+LIKN+I +P  +++  NI     G    CTFH+  +  CPIF+LG I  + G++
Sbjct: 168 APNFTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGES 227

Query: 242 FSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKE 301
           F+++A +GG++G+ I WDC+LD     C PKYSFRRLD K  +V    GYNFR+AKYYK 
Sbjct: 228 FTELAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYYKI 285

Query: 302 NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY-SS 360
           N    RTLIK +GIR D++V G  GKF +I  ++ + + L+  G+ +   D+++ T+ + 
Sbjct: 286 NGTTTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNK 345

Query: 361 NCCRSHIYPWCKCCQP 376
           N   SH   + K C P
Sbjct: 346 NKVYSH-KKFDKVCTP 360


>gi|28416921 purinergic receptor P2X2 isoform H [Homo sapiens]
          Length = 379

 Score =  203 bits (516), Expect = 4e-52
 Identities = 108/253 (42%), Positives = 153/253 (60%), Gaps = 9/253 (3%)

Query: 129 CSSDRGCKKGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALLNSAEN 187
           C SD  C  G +D    G++TGRCV  Y+G  KTCEV  WCP+E      +  L   A N
Sbjct: 44  CLSDADCVAGELDMLGNGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLGTMAPN 102

Query: 188 FTVLIKNNIDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETGDNFSD 244
           FT+LIKN+I +P  +++  NI     G    CTFH+  +  CPIF+LG I  + G++F++
Sbjct: 103 FTILIKNSIHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTE 162

Query: 245 VAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKENNV 304
           +A +GG++G+ I WDC+LD     C PKYSFRRLD K  +V    GYNFR+AKYYK N  
Sbjct: 163 LAHKGGVIGVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYYKINGT 220

Query: 305 EKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY-SSNCC 363
             RTLIK +GIR D++V G  GKF +I  ++ + + L+  G+ +   D+++ T+ + N  
Sbjct: 221 TTRTLIKAYGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKV 280

Query: 364 RSHIYPWCKCCQP 376
            SH   + K C P
Sbjct: 281 YSH-KKFDKVCTP 292


>gi|27881423 purinergic receptor P2X2 isoform I [Homo sapiens]
          Length = 399

 Score =  194 bits (492), Expect = 3e-49
 Identities = 103/245 (42%), Positives = 150/245 (61%), Gaps = 9/245 (3%)

Query: 137 KGWMDPQSKGIQTGRCV-VYEGNQKTCEVSAWCPIEAVEEAPRPALLNSAENFTVLIKNN 195
           +G +    +G++TGRCV  Y+G  KTCEV  WCP+E      +  L   A NFT+LIKN+
Sbjct: 72  RGGVREAPRGLRTGRCVPYYQGPSKTCEVFGWCPVEDGASVSQ-FLGTMAPNFTILIKNS 130

Query: 196 IDFPGHNYTTRNILP---GLNITCTFHKTQNPQCPIFRLGDIFRETGDNFSDVAIQGGIM 252
           I +P  +++  NI     G    CTFH+  +  CPIF+LG I  + G++F+++A +GG++
Sbjct: 131 IHYPKFHFSKGNIADRTDGYLKRCTFHEASDLYCPIFKLGFIVEKAGESFTELAHKGGVI 190

Query: 253 GIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYKENNVEKRTLIKV 312
           G+ I WDC+LD     C PKYSFRRLD K  +V    GYNFR+AKYYK N    RTLIK 
Sbjct: 191 GVIINWDCDLDLPASECNPKYSFRRLDPK--HVPASSGYNFRFAKYYKINGTTTRTLIKA 248

Query: 313 FGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTY-SSNCCRSHIYPWC 371
           +GIR D++V G  GKF +I  ++ + + L+  G+ +   D+++ T+ + N   SH   + 
Sbjct: 249 YGIRIDVIVHGQAGKFSLIPTIINLATALTSVGVGSFLCDWILLTFMNKNKVYSH-KKFD 307

Query: 372 KCCQP 376
           K C P
Sbjct: 308 KVCTP 312


>gi|28416935 purinergic receptor P2X5 isoform B [Homo sapiens]
          Length = 397

 Score =  188 bits (478), Expect = 1e-47
 Identities = 120/339 (35%), Positives = 173/339 (51%), Gaps = 41/339 (12%)

Query: 7   CSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEPVI-SSVHTK 64
           C  +F Y+T K    ++   G +       I +Y V +  +  K YQ  +  + S+V TK
Sbjct: 10  CLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITK 69

Query: 65  VKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCPEYPT 124
           VKG+A             L   ++D ADY  P Q                     P+   
Sbjct: 70  VKGVAFTN-------TSDLGQRIWDVADYVIPAQNEGI-----------------PD--- 102

Query: 125 RRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQK-TCEVSAWCPIEAVEEAPRPALLN 183
               CS D  C  G       G++TGRC+  E   + TCE+ AWCP+E     P    L 
Sbjct: 103 --GACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLET-SSRPEEPFLK 159

Query: 184 SAENFTVLIKNNIDFPGHNYTTRNILP----GLNITCTFHKTQNPQCPIFRLGDIFRETG 239
            AE+FT+ IKN+I FP  N++  N++         +C F   +N  CPIFRLG + R  G
Sbjct: 160 EAEDFTIFIKNHIRFPKFNFSN-NVMDVKDRSFLKSCHFGP-KNHYCPIFRLGSVIRWAG 217

Query: 240 DNFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYY 299
            +F D+A++GG++GI I W+C+LD+    C P YSF RLD+K +  S+  GYNFR+A+YY
Sbjct: 218 SDFQDIALEGGVIGINIEWNCDLDKAASECHPHYSFSRLDNKLSK-SVSSGYNFRFARYY 276

Query: 300 KE-NNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYI 337
           ++   VE RTL+K +GIRFD++V G G  F  + L+  I
Sbjct: 277 RDAAGVEFRTLMKAYGIRFDVMVNGKGAFFCDLVLIYLI 315


>gi|28416937 purinergic receptor P2X5 isoform C [Homo sapiens]
          Length = 178

 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 58/170 (34%), Positives = 81/170 (47%), Gaps = 12/170 (7%)

Query: 7   CSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSY-VCFALVSDKLYQRKEPVI-SSVHTK 64
           C  +F Y+T K    ++   G +       I +Y V +  +  K YQ  +  + S+V TK
Sbjct: 10  CLSLFDYKTEKYVIAKNKKVGLLYRLLQASILAYLVVWVFLIKKGYQDVDTSLQSAVITK 69

Query: 65  VKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQG-NSFFVMTNFLKTEGQEQRLCPEYP 123
           VKG+A             L   ++D ADY  P QG N FFV+TN + T  Q Q +C E  
Sbjct: 70  VKGVAFTN-------TSDLGQRIWDVADYVIPAQGENVFFVVTNLIVTPNQRQNVCAENE 122

Query: 124 -TRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQK-TCEVSAWCPIE 171
                 CS D  C  G       G++TGRC+  E   + TCE+ AWCP+E
Sbjct: 123 GIPDGACSKDSDCHAGEAVTAGNGVKTGRCLRRENLARGTCEIFAWCPLE 172


>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 1 [Homo sapiens]
          Length = 468

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 405 DESHIRMVNQQLLGRSLQDVKGQEVPRPAMD--FTDLSRLPLA-LHDTPPIPGQPEEIQL 461
           D +++ +++ +    + Q+++ +   R   D  F DL+  P   L   PP PG P+E   
Sbjct: 82  DSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGR 141

Query: 462 LRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGA 505
            + +A P     PV  QC  C     P    C  E+CCR +P A
Sbjct: 142 GQPDAVPEP--PPVGWQCPGCTFINKPTRPGC--EMCCRARPEA 181


>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
           isoform 2 [Homo sapiens]
          Length = 510

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 7/104 (6%)

Query: 405 DESHIRMVNQQLLGRSLQDVKGQEVPRPAMD--FTDLSRLPLA-LHDTPPIPGQPEEIQL 461
           D +++ +++ +    + Q+++ +   R   D  F DL+  P   L   PP PG P+E   
Sbjct: 124 DSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDLTLQPRGPLEPGPPKPGVPQEPGR 183

Query: 462 LRKEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCCRKKPGA 505
            + +A P     PV  QC  C     P    C  E+CCR +P A
Sbjct: 184 GQPDAVPEP--PPVGWQCPGCTFINKPTRPGC--EMCCRARPEA 223


>gi|13994364 keratin associated protein 3.2 [Homo sapiens]
          Length = 98

 Score = 36.2 bits (82), Expect = 0.088
 Identities = 14/30 (46%), Positives = 17/30 (56%)

Query: 477 CQCGSCLPSQLPESHRCLEELCCRKKPGAC 506
           C+CG CLPS  P +   LE +CC   P  C
Sbjct: 26  CRCGVCLPSTCPHTVWLLEPICCDNCPPPC 55


>gi|15055511 keratin associated protein 3-3 [Homo sapiens]
          Length = 98

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 14/30 (46%), Positives = 16/30 (53%)

Query: 477 CQCGSCLPSQLPESHRCLEELCCRKKPGAC 506
           C+CG CLPS  P +   LE  CC   P  C
Sbjct: 26  CRCGVCLPSTCPHTVWLLEPTCCDNCPPPC 55


>gi|13994362 keratin associated protein 3.1 [Homo sapiens]
          Length = 98

 Score = 35.0 bits (79), Expect = 0.20
 Identities = 13/30 (43%), Positives = 16/30 (53%)

Query: 477 CQCGSCLPSQLPESHRCLEELCCRKKPGAC 506
           C+CG CLPS  P     L+ +CC   P  C
Sbjct: 26  CRCGVCLPSTCPHEISLLQPICCDTCPPPC 55


>gi|224493895 t-complex 11 (mouse) like 1 [Homo sapiens]
          Length = 509

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 384 YRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLP 443
           Y    + + E K TL  +SF+   H R+ NQ      L  +K QE    A+D + L+   
Sbjct: 127 YDHAIKLVGEIKETL--LSFLLPGHTRLRNQITEVLDLDLIK-QEAENGALDISKLAEFI 183

Query: 444 LALHDTPPIPGQPEEIQLLR--KEATPRSRD 472
           + +  T   P + EE++ L+  KE  P  R+
Sbjct: 184 IGMMGTLCAPARDEEVKKLKDIKEIVPLFRE 214


>gi|224493847 t-complex 11 (mouse) like 1 [Homo sapiens]
          Length = 509

 Score = 30.4 bits (67), Expect = 4.8
 Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 5/91 (5%)

Query: 384 YRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRSLQDVKGQEVPRPAMDFTDLSRLP 443
           Y    + + E K TL  +SF+   H R+ NQ      L  +K QE    A+D + L+   
Sbjct: 127 YDHAIKLVGEIKETL--LSFLLPGHTRLRNQITEVLDLDLIK-QEAENGALDISKLAEFI 183

Query: 444 LALHDTPPIPGQPEEIQLLR--KEATPRSRD 472
           + +  T   P + EE++ L+  KE  P  R+
Sbjct: 184 IGMMGTLCAPARDEEVKKLKDIKEIVPLFRE 214


>gi|24497497 solute carrier family 22 member 7 isoform a [Homo
           sapiens]
          Length = 546

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 11/79 (13%)

Query: 2   PACCSCSDVFQYETNK-----------VTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKL 50
           PA   CS  ++Y+ ++           V   + +N     +FF  ++   V F  +SD+ 
Sbjct: 108 PATVPCSQGWEYDHSEFSSTIATEWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRF 167

Query: 51  YQRKEPVISSVHTKVKGIA 69
            +R+  +++ V T V G+A
Sbjct: 168 GRRRLLLVAYVSTLVLGLA 186


>gi|110347431 latent transforming growth factor beta binding protein
           4 isoform a [Homo sapiens]
          Length = 1624

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 16/68 (23%), Positives = 29/68 (42%), Gaps = 3/68 (4%)

Query: 443 PLALHDTPPIPGQPEEIQLLR---KEATPRSRDSPVWCQCGSCLPSQLPESHRCLEELCC 499
           P  + + P +P +P  + + R    + + RSR    +C+  SC P +     RCL  +  
Sbjct: 34  PSQVVEVPGVPSRPASVAVCRCCPGQTSRRSRCIRAFCRVRSCQPKKCAGPQRCLNPVPA 93

Query: 500 RKKPGACI 507
              P   +
Sbjct: 94  VPSPSPSV 101


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,768,250
Number of Sequences: 37866
Number of extensions: 1198831
Number of successful extensions: 3411
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3325
Number of HSP's gapped (non-prelim): 28
length of query: 595
length of database: 18,247,518
effective HSP length: 108
effective length of query: 487
effective length of database: 14,157,990
effective search space: 6894941130
effective search space used: 6894941130
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.