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Search of human proteins with 29171759
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29171759 adenylate cyclase activating polypeptide 1
(pituitary) receptor type I precursor [Homo sapiens]
(468 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 973 0.0
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 437 e-122
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 432 e-121
gi|114205383 secretin receptor precursor [Homo sapiens] 413 e-115
gi|58530851 growth hormone releasing hormone receptor isoform a ... 340 2e-93
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 278 8e-75
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 251 8e-67
gi|58530853 growth hormone releasing hormone receptor isoform b ... 249 5e-66
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 249 5e-66
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 246 2e-65
gi|4503947 glucagon receptor [Homo sapiens] 244 9e-65
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 243 3e-64
gi|4502547 calcitonin receptor [Homo sapiens] 198 1e-50
gi|5031621 calcitonin receptor-like [Homo sapiens] 185 7e-47
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 185 9e-47
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 179 4e-45
gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 175 9e-44
gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 164 2e-40
gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 148 1e-35
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 93 5e-19
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 84 4e-16
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 84 4e-16
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 84 4e-16
gi|163792198 latrophilin 3 precursor [Homo sapiens] 82 8e-16
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 80 4e-15
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 80 4e-15
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 80 5e-15
gi|40807489 egf-like module containing, mucin-like, hormone rece... 78 2e-14
gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens] 76 7e-14
gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens] 76 7e-14
>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
receptor type I precursor [Homo sapiens]
Length = 468
Score = 973 bits (2516), Expect = 0.0
Identities = 468/468 (100%), Positives = 468/468 (100%)
Query: 1 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN 60
MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN
Sbjct: 1 MAGVVHVSLAALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDN 60
Query: 61 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE 120
ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE
Sbjct: 61 ITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTE 120
Query: 121 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK 180
DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK
Sbjct: 121 DGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK 180
Query: 181 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN 240
LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN
Sbjct: 181 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN 240
Query: 241 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN 300
YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN
Sbjct: 241 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN 300
Query: 301 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP 360
DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP
Sbjct: 301 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP 360
Query: 361 LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV 420
LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV
Sbjct: 361 LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV 420
Query: 421 NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT 468
NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT
Sbjct: 421 NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMSGLPADNLAT 468
>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
Length = 438
Score = 437 bits (1124), Expect = e-122
Identities = 224/454 (49%), Positives = 293/454 (64%), Gaps = 39/454 (8%)
Query: 8 SLAALLLLPMAPAMHSDCIF----KKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITC 63
+L LL ++H +C F ++E+ C E ++ E C G+WDNITC
Sbjct: 8 ALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTE------KHKACSGVWDNITC 61
Query: 64 WKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGW 123
W+PA+VGE V V CP++F F S G +S+NCT DGW
Sbjct: 62 WRPANVGETVTVPCPKVFSNF-----------------------YSKAGNISKNCTSDGW 98
Query: 124 SEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHC 183
SE FP + DACG+ + E E+ + +Y+ VKA+YT+GYS SL++L T +ILC FRKLHC
Sbjct: 99 SETFPDFVDACGYSDPEDES--KITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHC 156
Query: 184 TRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCF---ISTVECKAVMVFFHYCVVSN 240
TRN+IH+NLF+SF+LRAISV +KD +LY+ + HC S V CK +VF YC+++N
Sbjct: 157 TRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMAN 216
Query: 241 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN 300
+FWL +EGLYL TLLV P RR F Y +IGWG PTVC+ W RLY +DTGCWD N
Sbjct: 217 FFWLLVEGLYLHTLLV-AMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTN 275
Query: 301 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP 360
D + WWVI+ P++ SI+VNFVLFI II IL+QKL SPD+GGN+ S Y RLA+STLLLIP
Sbjct: 276 DHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIP 335
Query: 361 LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV 420
LFG+HY VFA P ++S + +++FEL LGSFQG VVAVLYCFLN EVQ E+KRKWRS
Sbjct: 336 LFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCP 395
Query: 421 NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSS 454
+ D++ S + +G G Q S++ S
Sbjct: 396 TPSASRDYRVCGSSFSRNGSEGALQFHRGSRAQS 429
>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
Length = 457
Score = 432 bits (1110), Expect = e-121
Identities = 224/464 (48%), Positives = 303/464 (65%), Gaps = 44/464 (9%)
Query: 9 LAALLLLPMAPA------MHSDC----IFKKEQAMCLEKIQRANELMGFNDSSPGCPGMW 58
LA L + PA + +C + + + CLE+ Q NE +G C MW
Sbjct: 15 LAGALAWALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETIG-------CSKMW 67
Query: 59 DNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNC 118
DN+TCW G++V+++CP +F++F+ Q G + VSR+C
Sbjct: 68 DNLTCWPATPRGQVVVLACPLIFKLFSSIQ-------GRN---------------VSRSC 105
Query: 119 TEDGWS--EPFPHYFDACGFDEYESETGDQD-YYYLSVKALYTVGYSTSLVTLTTAMVIL 175
T++GW+ EP P Y ACG D+ + +Q +Y SVK YT+GY SL TL A IL
Sbjct: 106 TDEGWTHLEPGP-YPIACGLDDKAASLDEQQTMFYGSVKTGYTIGYGLSLATLLVATAIL 164
Query: 176 CRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHY 235
FRKLHCTRN+IHM+LF+SF+LRA +VFIKD L+ +S+ C +V CKA MVFF Y
Sbjct: 165 SLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLALFDSGESDQCSEGSVGCKAAMVFFQY 224
Query: 236 CVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTG 295
CV++N+FWL +EGLYL+TLL +FF ER+YF+ Y +IGWG P+ VW R++F+D G
Sbjct: 225 CVMANFFWLLVEGLYLYTLLAVSFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYG 284
Query: 296 CWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARST 355
CWD +S +LWW+IKGP++ SI+VNF+LFI II IL+QKL+ PD+ ++SS Y RLARST
Sbjct: 285 CWDTINS-SLWWIIKGPILTSILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARST 343
Query: 356 LLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKW 415
LLLIPLFG+HY +FAF P+N ++VFEL +GSFQGFVVA+LYCFLNGEVQAE++RKW
Sbjct: 344 LLLIPLFGVHYIMFAFFPDNFKPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKW 403
Query: 416 RSWKVNRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMS 459
R W + + K+RHPS S+G TQ+S+L++ S R S
Sbjct: 404 RRWHLQGVLGWNPKYRHPSGGSNGATCSTQVSMLTRVSPGARRS 447
>gi|114205383 secretin receptor precursor [Homo sapiens]
Length = 440
Score = 413 bits (1062), Expect = e-115
Identities = 206/432 (47%), Positives = 273/432 (63%), Gaps = 34/432 (7%)
Query: 29 KEQAMCLEKIQRANEL-MGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPD 87
+EQ CL+++ R +G PGC GMWDNI+CW + G MV V CP R+
Sbjct: 40 EEQDQCLQELSREQTGDLGTEQPVPGCEGMWDNISCWPSSVPGRMVEVECPRFLRMLT-- 97
Query: 88 QVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQD 147
S G + RNCT+DGWSE FP ACG + +S +
Sbjct: 98 ---------------------SRNGSLFRNCTQDGWSETFPRPNLACGVNVNDSSNEKRH 136
Query: 148 YYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKD 207
Y L +K +YTVGYS+SLV L A+ ILC FR+LHCTRN+IHM+LFVSF+LRA+S FIKD
Sbjct: 137 SYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILRALSNFIKD 196
Query: 208 WILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFY 267
+L++ D +C CK VMV F YC+++NY WL +EGLYL TLL +FF ER+Y
Sbjct: 197 AVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISFFSERKYLQ 256
Query: 268 WYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGI 327
+ GWG+P + V +WA R + +D GCWD+N + ++WW+I+GPV+ SI++NF+LFI I
Sbjct: 257 GFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRGPVILSILINFILFINI 316
Query: 328 IVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELG 387
+ IL++KL++ + GNE S Y RLARSTLLLIPLFGIHY VFAFSPE+ + + L FEL
Sbjct: 317 LRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSPEDAMEIQ-LFFELA 375
Query: 388 LGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGGTQLS 447
LGSFQG VVAVLYCFLNGEVQ E+++KW+ W + + P + + T+ S
Sbjct: 376 LGSFQGLVVAVLYCFLNGEVQLEVQKKWQQWHLREF---------PLHPVASFSNSTKAS 426
Query: 448 ILSKSSSQIRMS 459
L +S R S
Sbjct: 427 HLEQSQGTCRTS 438
>gi|58530851 growth hormone releasing hormone receptor isoform a
precursor [Homo sapiens]
Length = 423
Score = 340 bits (872), Expect = 2e-93
Identities = 172/399 (43%), Positives = 238/399 (59%), Gaps = 35/399 (8%)
Query: 21 MHSDCIF----KKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVS 76
MH +C F +++++ CL Q A E+ +++ GCP WD + CW A GE V +
Sbjct: 24 MHPECDFITQLREDESACL---QAAEEMP---NTTLGCPATWDGLLCWPTAGSGEWVTLP 77
Query: 77 CPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGF 136
CP+ F F+ S+ G V R+CT GWSEPFP Y AC
Sbjct: 78 CPDFFSHFS-----------------------SESGAVKRDCTITGWSEPFPPYPVACPV 114
Query: 137 DEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSF 196
+++ Y+ +VK +YTVG+S S+V L A+ IL R+LHC RN++H LF +F
Sbjct: 115 PL--ELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
Query: 197 MLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLV 256
+L+A +VF+KD L+ D++HC STV CK + H+ ++N+ WL E +YL LL
Sbjct: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
Query: 257 ETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGS 316
T RR F+W + GWG P + W + +L F+D CWD++D++ WW+IKGP+V S
Sbjct: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLS 292
Query: 317 IMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENV 376
+ VNF LF+ II ILV+KL+ + S Y RL++STL LIPLFGIHY +F F P+N
Sbjct: 293 VGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNA 352
Query: 377 SKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKW 415
RL ELGLGSFQGF+VA+LYCFLN EV+ EI RKW
Sbjct: 353 GLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKW 391
>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
Length = 593
Score = 278 bits (711), Expect = 8e-75
Identities = 162/443 (36%), Positives = 242/443 (54%), Gaps = 67/443 (15%)
Query: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
C WD+I CW GE+V V CP+ FN G
Sbjct: 108 CLPEWDHILCWPLGAPGEVVAVPCPDYIYDFN------------------------HKGH 143
Query: 114 VSRNCTEDGWSEPFP-------HYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLV 166
R C +G E P +Y + F +ET +++ + + +YTVGYS SL
Sbjct: 144 AYRRCDRNGSWELVPGHNRTWANYSECVKF--LTNETREREVFD-RLGMIYTVGYSVSLA 200
Query: 167 TLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVE- 225
+LT A++IL FR+LHCTRN+IHM+LF+SFMLRA+S+F+KD +LY+ + T E
Sbjct: 201 SLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEE 260
Query: 226 --------------------CKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRY 265
C+ + FF Y + +NY+W+ +EGLYL +L+ FF E++Y
Sbjct: 261 LRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKY 320
Query: 266 FYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFI 325
+ +T+ GWG P V V VW ++R +TGCWD++ W+I+ P++ SI++NF+LFI
Sbjct: 321 LWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK-WIIQVPILASIVLNFILFI 379
Query: 326 GIIVILVQKLQSPDMGGNES-SIYLRLARSTLLLIPLFGIHYTVFAFSP----ENVSKRE 380
I+ +L KL+ + G ++ Y +L +STL+L+PLFG+HY VF +P +
Sbjct: 380 NIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQV 439
Query: 381 RLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGV 440
++ +E+ SFQGF VA++YCF NGEVQAEIK+ W W + A+DFK + S SS
Sbjct: 440 QMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTL----ALDFKRKARS-GSSSY 494
Query: 441 NGGTQLSILSKSSSQIRMS-GLP 462
+ G +S S ++ R+ GLP
Sbjct: 495 SYGPMVSHTSVTNVGPRVGLGLP 517
>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
Length = 550
Score = 251 bits (642), Expect = 8e-67
Identities = 143/436 (32%), Positives = 231/436 (52%), Gaps = 62/436 (14%)
Query: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
C WD + CW VG++ V CP FN GV
Sbjct: 63 CFPEWDGLICWPRGTVGKISAVPCPPYIYDFN------------------------HKGV 98
Query: 114 VSRNCTEDG-W------SEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLV 166
R+C +G W ++ + +Y D F + + G Q+++ + +YTVGYS S
Sbjct: 99 AFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFE-RLYVMYTVGYSISFG 157
Query: 167 TLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYA------------EQ 214
+L A++I+ FR+LHCTRN+IHM+LFVSFMLRA S+F+KD +++A +
Sbjct: 158 SLAVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQD 217
Query: 215 DSNHCFIST-------VECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFY 267
D + +T + CK +V F Y + +NY+W+ +EGLYL L+ FF + +Y +
Sbjct: 218 DPQNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLW 277
Query: 268 WYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGI 327
+ +IGWG P V WA R D CW+++ + + W+ + P++ +I +NF+LF+
Sbjct: 278 GFILIGWGFPAAFVAAWAVARATLADARCWELS-AGDIKWIYQAPILAAIGLNFILFLNT 336
Query: 328 IVILVQKLQSPDMGGNES-SIYLRLARSTLLLIPLFGIHYTVFAFSPEN---VSKRERLV 383
+ +L K+ + G+++ Y +LA+STL+L+ +FG+HY VF P + + R+
Sbjct: 337 VRVLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMH 396
Query: 384 FELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSLASSGVNGG 443
EL SFQGF V+++YC+ NGEVQAE+K+ W W + +VD+K P S G
Sbjct: 397 CELFFNSFQGFFVSIIYCYCNGEVQAEVKKMWSRWNL----SVDWKRTPP--CGSRRCGS 450
Query: 444 TQLSILSKSSSQIRMS 459
++ +SSQ +++
Sbjct: 451 VLTTVTHSTSSQSQVA 466
>gi|58530853 growth hormone releasing hormone receptor isoform b
precursor [Homo sapiens]
Length = 337
Score = 249 bits (635), Expect = 5e-66
Identities = 125/320 (39%), Positives = 183/320 (57%), Gaps = 35/320 (10%)
Query: 21 MHSDCIF----KKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVS 76
MH +C F +++++ CL Q A E+ +++ GCP WD + CW A GE V +
Sbjct: 24 MHPECDFITQLREDESACL---QAAEEMP---NTTLGCPATWDGLLCWPTAGSGEWVTLP 77
Query: 77 CPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGF 136
CP+ F F+ S+ G V R+CT GWSEPFP Y AC
Sbjct: 78 CPDFFSHFS-----------------------SESGAVKRDCTITGWSEPFPPYPVACPV 114
Query: 137 DEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSF 196
+++ Y+ +VK +YTVG+S S+V L A+ IL R+LHC RN++H LF +F
Sbjct: 115 PL--ELLAEEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTF 172
Query: 197 MLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLV 256
+L+A +VF+KD L+ D++HC STV CK + H+ ++N+ WL E +YL LL
Sbjct: 173 ILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLA 232
Query: 257 ETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGS 316
T RR F+W + GWG P + W + +L F+D CWD++D++ WW+IKGP+V S
Sbjct: 233 STSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLS 292
Query: 317 IMVNFVLFIGIIVILVQKLQ 336
+ VNF LF+ II ILV+KL+
Sbjct: 293 VGVNFGLFLNIIRILVRKLE 312
>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
Length = 466
Score = 249 bits (635), Expect = 5e-66
Identities = 144/384 (37%), Positives = 204/384 (53%), Gaps = 37/384 (9%)
Query: 50 SSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLS 109
S C G +D CW A SCP W
Sbjct: 57 SGLACNGSFDMYVCWDYAAPNATARASCPWYLP-------WHHHVAA------------- 96
Query: 110 DMGVVSRNCTEDG-WSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTL 168
G V R C DG W H C E DQ ++ +YTVGYS SL TL
Sbjct: 97 --GFVLRQCGSDGQWGLWRDH--TQCENPEKNEAFLDQRLILERLQVMYTVGYSLSLATL 152
Query: 169 TTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWIL------YAEQDSNHCFIS 222
A++IL FR+LHCTRN+IH+NLF SFMLRA ++ +D +L +Q +
Sbjct: 153 LLALLILSLFRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQA 212
Query: 223 TVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVT 282
C+ + YCV +NY WL +EG+YL +LLV E +F +Y ++GWG P + V
Sbjct: 213 LAACRTAQIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVI 272
Query: 283 VWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGG 342
W +R +++T CW+ N+ A+WW+I+ P++ +I++NF++FI I+ IL+ KL++ M
Sbjct: 273 PWVIVRYLYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRC 332
Query: 343 NESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKR----ERLVFELGLGSFQGFVVAV 398
+ LRLARSTL L+PL G+H VFA E ++ +L FE+ L SFQGF+V+V
Sbjct: 333 RD--YRLRLARSTLTLVPLLGVHEVVFAPVTEEQARGALRFAKLGFEIFLSSFQGFLVSV 390
Query: 399 LYCFLNGEVQAEIKRKWRSWKVNR 422
LYCF+N EVQ+EI+R W ++ R
Sbjct: 391 LYCFINKEVQSEIRRGWHHCRLRR 414
>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
sapiens]
Length = 553
Score = 246 bits (629), Expect = 2e-65
Identities = 143/389 (36%), Positives = 212/389 (54%), Gaps = 44/389 (11%)
Query: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
C G +D CW + G V V CP W E+ G +
Sbjct: 96 CNGTFDQYVCWPHSSPGN-VSVPCPSYL------PWWSEESSGRA--------------- 133
Query: 114 VSRNCTEDGWSEPFPHYFDACGFDEYESETG----DQDYYYL--SVKALYTVGYSTSLVT 167
R+C G + + D D SE + D Y L +++ +YTVGYS SL++
Sbjct: 134 -YRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLIS 192
Query: 168 LTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILY----AEQDSNHCFIS- 222
L A+ +L RKLHCTRN+IHMNLF SF+LR ++V +KD + Y D+ + ++S
Sbjct: 193 LFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYSKRPDNENGWMSY 252
Query: 223 ----TVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPT 278
+ C++V V HY V +NY WL +EGLYL TLL T PERR + Y ++GW P
Sbjct: 253 LSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPV 312
Query: 279 VCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSP 338
+ V W R + ++TGCW N + +WW+I+GP++ + VNF +F+ I+ +L+ KL++
Sbjct: 313 LFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAH 372
Query: 339 DMGGNESSIYLRLARSTLLLIPLFGIHYTVFAF----SPENVSKRERLVFELGLGSFQGF 394
M + RLA+STL+LIPL G+H +F+F E +K RL +L L SF GF
Sbjct: 373 QMCFRDYK--YRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGF 430
Query: 395 VVAVLYCFLNGEVQAEIKRKWRSWKVNRY 423
+VA+ Y F NGEV+AE+++ W + + R+
Sbjct: 431 LVALQYGFANGEVKAELRKYWVRFLLARH 459
>gi|4503947 glucagon receptor [Homo sapiens]
Length = 477
Score = 244 bits (624), Expect = 9e-65
Identities = 125/287 (43%), Positives = 176/287 (61%), Gaps = 16/287 (5%)
Query: 150 YLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWI 209
Y S + +YTVGYS SL L A+ IL KLHCTRN IH NLF SF+L+A SV + D +
Sbjct: 138 YSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGL 197
Query: 210 L---YAEQDSNHCFIST-------VECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETF 259
L Y+++ + +ST C+ VF Y +V+NY WL +EGLYL LL
Sbjct: 198 LRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLAT 257
Query: 260 FPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMV 319
PER +F Y IGWG P + V WA ++ F++ CW ND+ WW+++ PV +I++
Sbjct: 258 LPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILI 317
Query: 320 NFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAF----SPEN 375
NF +F+ I+ +LV KL++ M + + RLA+STL LIPL G+H VFAF +
Sbjct: 318 NFFIFVRIVQLLVAKLRARQM--HHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQG 375
Query: 376 VSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNR 422
+ +L F+L L SFQG +VAVLYCFLN EVQ+E++R+W W++ +
Sbjct: 376 TLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGK 422
>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
Length = 463
Score = 243 bits (620), Expect = 3e-64
Identities = 146/416 (35%), Positives = 206/416 (49%), Gaps = 47/416 (11%)
Query: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
C +D CW G V VSCP W + G
Sbjct: 62 CNRTFDEYACWPDGEPGSFVNVSCPWYLP-------WASSV---------------PQGH 99
Query: 114 VSRNCTEDG-WSEPFPHYFDACGFDEYES----ETGDQDYYYLSVKALYTVGYSTSLVTL 168
V R CT +G W + E E E + L + +YTVGY+ S L
Sbjct: 100 VYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSAL 159
Query: 169 TTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWIL---YAEQDSNH------C 219
A IL FR LHCTRN+IH+NLF SF+LRA+SVFIKD L Y+ H
Sbjct: 160 VIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLS 219
Query: 220 FISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTV 279
+ ++ C+ V + YCV +NY+WL +EG+YL+TLL + E+ F Y IGWG P +
Sbjct: 220 YQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLL 279
Query: 280 CVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPD 339
V W ++ ++D GCW N + W +I+ P++ +I VNF++F+ +I I+V KL++
Sbjct: 280 FVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANL 339
Query: 340 MGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRE----RLVFELGLGSFQGFV 395
M ++ I RLA+STL LIPL G H +FAF + ++ +L EL SFQG +
Sbjct: 340 M--CKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLM 397
Query: 396 VAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHP-----SLASSGVNGGTQL 446
VA+LYCF+N EVQ E ++ W W++ P S SSG G+ +
Sbjct: 398 VAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSM 453
>gi|4502547 calcitonin receptor [Homo sapiens]
Length = 474
Score = 198 bits (503), Expect = 1e-50
Identities = 119/399 (29%), Positives = 192/399 (48%), Gaps = 48/399 (12%)
Query: 31 QAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVW 90
Q C +++Q +L + P C WD CW G + CP+ F F+P +
Sbjct: 52 QYKCYDRMQ---QLPAYQGEGPYCNRTWDGWLCWDDTPAGVLSYQFCPDYFPDFDPSEK- 107
Query: 91 ETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHY------FDACGFDEYESETG 144
V++ C E G P + C E
Sbjct: 108 -----------------------VTKYCDEKGVWFKHPENNRTWSNYTMCNAFTPEKLKN 144
Query: 145 DQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVF 204
YYL++ VG+S S+ TL ++ I FR L C R +H N+F++++L ++ +
Sbjct: 145 AYVLYYLAI-----VGHSLSIFTLVISLGIFVFFRSLGCQRVTLHKNMFLTYILNSMIII 199
Query: 205 IKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERR 264
I ++ + V CK + F Y + NYFW+ EG+YL TL+V F E++
Sbjct: 200 IH--LVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEGIYLHTLIVVAVFTEKQ 257
Query: 265 YFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLF 324
WY ++GWG P V T+ A R + + CW ++ T L ++I GPV+ +++VNF
Sbjct: 258 RLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCW-LSVETHLLYIIHGPVMAALVVNFFFL 316
Query: 325 IGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVF 384
+ I+ +LV K++ ES +YL+ ++T++L+PL GI + VF + P N K ++
Sbjct: 317 LNIVRVLVTKMRETHEA--ESHMYLKAVKATMILVPLLGIQFVVFPWRPSN--KMLGKIY 372
Query: 385 ELGLGS---FQGFVVAVLYCFLNGEVQAEIKRKWRSWKV 420
+ + S FQGF VA +YCF N EVQ +KR+W +K+
Sbjct: 373 DYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKI 411
>gi|5031621 calcitonin receptor-like [Homo sapiens]
Length = 461
Score = 185 bits (470), Expect = 7e-47
Identities = 108/379 (28%), Positives = 181/379 (47%), Gaps = 51/379 (13%)
Query: 54 CPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGV 113
C WD CW G + CP+ F+ F+P +
Sbjct: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEK------------------------ 100
Query: 114 VSRNCTEDG-WSEPFPH--------YFDACGFDEYESETGDQDYYYLSVKALYTVGYSTS 164
V++ C +DG W F H + C + +E + +YL++ +G+ S
Sbjct: 101 VTKICDQDGNW---FRHPASNRTWTNYTQCNVNTHEKVKTALNLFYLTI-----IGHGLS 152
Query: 165 LVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFIST- 223
+ +L ++ I F+ L C R +H NLF SF+ ++ I +N ++T
Sbjct: 153 IASLLISLGIFFYFKSLSCQRITLHKNLFFSFVCNSVVTIIH----LTAVANNQALVATN 208
Query: 224 -VECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVT 282
V CK Y + NYFW+ EG+YL TL+V F E+++ WY +GWG P +
Sbjct: 209 PVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPAC 268
Query: 283 VWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGG 342
+ A R + + CW +D T L ++I GP+ +++VN + I+ +L+ KL+
Sbjct: 269 IHAIARSLYYNDNCWISSD-THLLYIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQA- 326
Query: 343 NESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELG-LGSFQGFVVAVLYC 401
ES++Y++ R+TL+L+PL GI + + + PE E + + L FQG +V+ ++C
Sbjct: 327 -ESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFC 385
Query: 402 FLNGEVQAEIKRKWRSWKV 420
F NGEVQA ++R W +K+
Sbjct: 386 FFNGEVQAILRRNWNQYKI 404
>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
sapiens]
Length = 411
Score = 185 bits (469), Expect = 9e-47
Identities = 106/362 (29%), Positives = 181/362 (50%), Gaps = 36/362 (9%)
Query: 62 TCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTED 121
TCW + G +V CPE F N + + R C E+
Sbjct: 49 TCWPRSAAGALVERPCPEYF----------------------NGVKYNTTRNAYRECLEN 86
Query: 122 G-WSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRK 180
G W+ + D+ + + D +Y + +G+ S+ L A ++ R
Sbjct: 87 GTWASKINYSQCEPILDDKQRK---YDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRS 143
Query: 181 LHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSN 240
+ C RN IH NL +F+LR + F+ + + +SN V C+ + F+Y VV+N
Sbjct: 144 IRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNE-----VWCRCITTIFNYFVVTN 198
Query: 241 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCW-DM 299
+FW+F+EG YL T +V T+ ER + IGW P + WA +LY+++ CW
Sbjct: 199 FFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGK 258
Query: 300 NDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLI 359
+ ++ +GP++ +++NFV I+ IL+ KL++ +E+ Y + ++TL+L+
Sbjct: 259 EPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLL 316
Query: 360 PLFGIHYTVFAFSP--ENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRS 417
PL GI Y +F +P +++S+ + F L SFQGF V+V YCF NGEV++ ++++W
Sbjct: 317 PLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHR 376
Query: 418 WK 419
W+
Sbjct: 377 WQ 378
>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
[Homo sapiens]
Length = 415
Score = 179 bits (455), Expect = 4e-45
Identities = 125/419 (29%), Positives = 201/419 (47%), Gaps = 58/419 (13%)
Query: 11 ALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNI-TCWKPAHV 69
ALLLL + P S Q E + A+ + G C D I TCW +
Sbjct: 12 ALLLLGLNPVSAS------LQDQHCESLSLASNISGLQ-----CNASVDLIGTCWPRSPA 60
Query: 70 GEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPH 129
G++V+ CP F +G V N T +G+ E +
Sbjct: 61 GQLVVRPCPAFF------------------YG------------VRYNTTNNGYRECLAN 90
Query: 130 YFDACGFDEYE------SETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHC 183
A + E E + +Y+++V Y +G+ SLV L A V+ R R + C
Sbjct: 91 GSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRC 149
Query: 184 TRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFW 243
RN IH NL +F+LR + F+ + E ++ C+ V ++Y V+N+FW
Sbjct: 150 LRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSN----VGWCRLVTAAYNYFHVTNFFW 205
Query: 244 LFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCW-DMNDS 302
+F EG YL T +V T+ +R + + IGWG P + WA +LY+D+ CW
Sbjct: 206 MFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPG 265
Query: 303 TALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLF 362
++ +GP++ +++NF+ I+ IL+ KL++ +E+ Y + ++TL+L+PL
Sbjct: 266 VYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLL 323
Query: 363 GIHYTVFAFSP--ENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWK 419
GI Y +F +P + VS+ + F L SFQGF V+V YCFLN EV++ I+++W W+
Sbjct: 324 GITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQ 382
>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
[Homo sapiens]
Length = 375
Score = 175 bits (443), Expect = 9e-44
Identities = 94/275 (34%), Positives = 156/275 (56%), Gaps = 10/275 (3%)
Query: 148 YYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKD 207
+Y+++V Y +G+ SLV L A V+ R R + C RN IH NL +F+LR + F+
Sbjct: 75 HYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQ 133
Query: 208 WILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFY 267
+ E ++ C+ V ++Y V+N+FW+F EG YL T +V T+ +R +
Sbjct: 134 LTMSPEVHQSN----VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKW 189
Query: 268 WYTIIGWGTPTVCVTVWATLRLYFDDTGCW-DMNDSTALWWVIKGPVVGSIMVNFVLFIG 326
+ IGWG P + WA +LY+D+ CW ++ +GP++ +++NF+
Sbjct: 190 MFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFN 249
Query: 327 IIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSP--ENVSKRERLVF 384
I+ IL+ KL++ +E+ Y + ++TL+L+PL GI Y +F +P + VS+ + F
Sbjct: 250 IVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYF 307
Query: 385 ELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWK 419
L SFQGF V+V YCFLN EV++ I+++W W+
Sbjct: 308 NSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQ 342
>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
[Homo sapiens]
Length = 444
Score = 164 bits (415), Expect = 2e-40
Identities = 125/448 (27%), Positives = 201/448 (44%), Gaps = 87/448 (19%)
Query: 11 ALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNI-TCWKPAHV 69
ALLLL + P S Q E + A+ + G C D I TCW +
Sbjct: 12 ALLLLGLNPVSAS------LQDQHCESLSLASNISGLQ-----CNASVDLIGTCWPRSPA 60
Query: 70 GEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPH 129
G++V+ CP F +G V N T +G+ E +
Sbjct: 61 GQLVVRPCPAFF------------------YG------------VRYNTTNNGYRECLAN 90
Query: 130 YFDACGFDEYE------SETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFR---- 179
A + E E + +Y+++V Y +G+ SLV L A V+ R R
Sbjct: 91 GSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRPGCT 149
Query: 180 -------------------------KLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQ 214
+ C RN IH NL +F+LR + F+ + E
Sbjct: 150 HWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 209
Query: 215 DSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGW 274
++ C+ V ++Y V+N+FW+F EG YL T +V T+ +R + + IGW
Sbjct: 210 HQSN----VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGW 265
Query: 275 GTPTVCVTVWATLRLYFDDTGCW-DMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQ 333
G P + WA +LY+D+ CW ++ +GP++ +++NF+ I+ IL+
Sbjct: 266 GVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMT 325
Query: 334 KLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSP--ENVSKRERLVFELGLGSF 391
KL++ +E+ Y + ++TL+L+PL GI Y +F +P + VS+ + F L SF
Sbjct: 326 KLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESF 383
Query: 392 QGFVVAVLYCFLNGEVQAEIKRKWRSWK 419
QGF V+V YCFLN EV++ I+++W W+
Sbjct: 384 QGFFVSVFYCFLNSEVRSAIRKRWHRWQ 411
>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
[Homo sapiens]
Length = 401
Score = 148 bits (373), Expect = 1e-35
Identities = 115/419 (27%), Positives = 190/419 (45%), Gaps = 72/419 (17%)
Query: 11 ALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNI-TCWKPAHV 69
ALLLL + P S Q E + A+ + G C D I TCW +
Sbjct: 12 ALLLLGLNPVSAS------LQDQHCESLSLASNISGLQ-----CNASVDLIGTCWPRSPA 60
Query: 70 GEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPH 129
G++V+ CP F +G V N T +G+ E +
Sbjct: 61 GQLVVRPCPAFF------------------YG------------VRYNTTNNGYRECLAN 90
Query: 130 YFDACGFDEYE------SETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHC 183
A + E E + +Y+++V Y +G+ SLV L A V+ R R + C
Sbjct: 91 GSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRC 149
Query: 184 TRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFW 243
RN IH NL +F+LR + F+ + E ++ C+ V ++Y V+N+FW
Sbjct: 150 LRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSN----VGWCRLVTAAYNYFHVTNFFW 205
Query: 244 LFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCW-DMNDS 302
+F EG YL T +V T+ +R + + IGWG P + WA +LY+D+ CW
Sbjct: 206 MFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPG 265
Query: 303 TALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLF 362
++ +GP++ +++NF+ I+ IL+ KL++ +E+ Y + ++TL+L+PL
Sbjct: 266 VYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLL 323
Query: 363 GIHYTVFAFSP--ENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWK 419
GI Y +F +P + VS+ + F L SFQ V++ I+++W W+
Sbjct: 324 GITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQ 368
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 93.2 bits (230), Expect = 5e-19
Identities = 77/324 (23%), Positives = 141/324 (43%), Gaps = 21/324 (6%)
Query: 149 YYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRN---FIHMNLFVSFMLRAISVFI 205
+ +++ ++ VG S S++ L +V + RN IH NL + ++ + + I
Sbjct: 562 HQVALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLI 621
Query: 206 KDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRY 265
S T C+ + V HY +S + W+ +EGL+L++++++ F E
Sbjct: 622 ----------SFRLEPGTTPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSK 671
Query: 266 FYWYTIIGWGTP-TVC-VTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVL 323
+Y +GWG P +C +++ + Y CW S A+W + P + I+VN +
Sbjct: 672 HRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCWLSLASGAIWAFV-APALFVIVVNIGI 730
Query: 324 FIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLV 383
I + ++ Q + S + A++ +L+P+ G + + + + +
Sbjct: 731 LIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCAVVFQYM 790
Query: 384 FELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFA--VDFKHRHPSLASSGVN 441
F L S QG + + +C LN EV+A K K + W + A + K H L +
Sbjct: 791 FAT-LNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSARTSNAKPFHSDLMNGTRP 849
Query: 442 G--GTQLSILSKSSSQIRMSGLPA 463
G T+LS KSS L A
Sbjct: 850 GMASTKLSPWDKSSHSAHRVDLSA 873
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 83.6 bits (205), Expect = 4e-16
Identities = 72/261 (27%), Positives = 118/261 (45%), Gaps = 17/261 (6%)
Query: 159 VGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNH 218
VG + SL L ++ R + +R IH++L I +F+ I A ++
Sbjct: 504 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHL-------CICLFVGSTIFLAGIENEG 556
Query: 219 CFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPT 278
+ + C+ V HYC ++ + W+ +EGL L+ L+V F + W +IG+G P
Sbjct: 557 GQVG-LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPL 615
Query: 279 VCVTVWATL--RLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQ 336
+ V V A + + Y CW ++ W GPV I+ N V+F+ + L QK
Sbjct: 616 LIVGVSAAIYSKGYGRPRYCW-LDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 674
Query: 337 --SPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGF 394
+PDM + + L + L L G + F ++ S VF + L QG
Sbjct: 675 EINPDMKKLKKARALTITAIAQLF--LLGCTWVFGLFIFDDRSLVLTYVFTI-LNCLQGA 731
Query: 395 VVAVLYCFLNGEVQAEIKRKW 415
+ +L+C LN +V+ E RKW
Sbjct: 732 FLYLLHCLLNKKVREEY-RKW 751
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 83.6 bits (205), Expect = 4e-16
Identities = 72/261 (27%), Positives = 118/261 (45%), Gaps = 17/261 (6%)
Query: 159 VGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNH 218
VG + SL L ++ R + +R IH++L I +F+ I A ++
Sbjct: 460 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHL-------CICLFVGSTIFLAGIENEG 512
Query: 219 CFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPT 278
+ + C+ V HYC ++ + W+ +EGL L+ L+V F + W +IG+G P
Sbjct: 513 GQVG-LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPL 571
Query: 279 VCVTVWATL--RLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQ 336
+ V V A + + Y CW ++ W GPV I+ N V+F+ + L QK
Sbjct: 572 LIVGVSAAIYSKGYGRPRYCW-LDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 630
Query: 337 --SPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGF 394
+PDM + + L + L L G + F ++ S VF + L QG
Sbjct: 631 EINPDMKKLKKARALTITAIAQLF--LLGCTWVFGLFIFDDRSLVLTYVFTI-LNCLQGA 687
Query: 395 VVAVLYCFLNGEVQAEIKRKW 415
+ +L+C LN +V+ E RKW
Sbjct: 688 FLYLLHCLLNKKVREEY-RKW 707
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 83.6 bits (205), Expect = 4e-16
Identities = 72/261 (27%), Positives = 118/261 (45%), Gaps = 17/261 (6%)
Query: 159 VGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNH 218
VG + SL L ++ R + +R IH++L I +F+ I A ++
Sbjct: 553 VGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHL-------CICLFVGSTIFLAGIENEG 605
Query: 219 CFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPT 278
+ + C+ V HYC ++ + W+ +EGL L+ L+V F + W +IG+G P
Sbjct: 606 GQVG-LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPL 664
Query: 279 VCVTVWATL--RLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQ 336
+ V V A + + Y CW ++ W GPV I+ N V+F+ + L QK
Sbjct: 665 LIVGVSAAIYSKGYGRPRYCW-LDFEQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFS 723
Query: 337 --SPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGF 394
+PDM + + L + L L G + F ++ S VF + L QG
Sbjct: 724 EINPDMKKLKKARALTITAIAQLF--LLGCTWVFGLFIFDDRSLVLTYVFTI-LNCLQGA 780
Query: 395 VVAVLYCFLNGEVQAEIKRKW 415
+ +L+C LN +V+ E RKW
Sbjct: 781 FLYLLHCLLNKKVREEY-RKW 800
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 82.4 bits (202), Expect = 8e-16
Identities = 75/267 (28%), Positives = 116/267 (43%), Gaps = 31/267 (11%)
Query: 159 VGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNH 218
VG SLV L + C FR L RN IH NL +S + + I I +Q
Sbjct: 883 VGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIG--INRTDQP--- 937
Query: 219 CFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPE---RRYFYWYTIIGWG 275
+ C H+ ++ + W+F+EG+ L+ +LVE F E R+YFY ++G+G
Sbjct: 938 -----IACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFY---LVGYG 989
Query: 276 TPTVCVTVWATL--RLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILV- 332
P + V V A + R Y D CW D+ +W I GP IM+N V+F+GI + +
Sbjct: 990 MPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFI-GPATLIIMLN-VIFLGIALYKMF 1047
Query: 333 --QKLQSPDMGGNESSIY-------LRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLV 383
+ P+ G ++ Y + L+ L G+ + F N S
Sbjct: 1048 HHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTW-AFGLMYINESTVIMAY 1106
Query: 384 FELGLGSFQGFVVAVLYCFLNGEVQAE 410
S QG + + +C L +V+ E
Sbjct: 1107 LFTIFNSLQGMFIFIFHCVLQKKVRKE 1133
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 80.1 bits (196), Expect = 4e-15
Identities = 73/267 (27%), Positives = 118/267 (44%), Gaps = 18/267 (6%)
Query: 151 LSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWIL 210
L + + VG SLV L + C R L RN IH NL I++F+ + +
Sbjct: 858 LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNL-------CINLFLAELLF 910
Query: 211 YAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYT 270
D I+ C HY ++ + WL +EG++L+ LLVE F E +Y
Sbjct: 911 LVGIDKTQYEIA---CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYY 967
Query: 271 IIGWGTPTVCVTVWATL--RLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGII 328
+ G+ P + V + A + R Y + CW D+ +W I GPV I+VN V ++
Sbjct: 968 LGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFI-GPVSFVIVVNLVF---LM 1023
Query: 329 VILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFEL-- 386
V L + ++S + +SS + L I L + +AF ++K ++ L
Sbjct: 1024 VTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFT 1083
Query: 387 GLGSFQGFVVAVLYCFLNGEVQAEIKR 413
+FQG + V +C L +V E +
Sbjct: 1084 TFNAFQGVFIFVFHCALQKKVHKEYSK 1110
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 80.1 bits (196), Expect = 4e-15
Identities = 73/267 (27%), Positives = 118/267 (44%), Gaps = 18/267 (6%)
Query: 151 LSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWIL 210
L + + VG SLV L + C R L RN IH NL I++F+ + +
Sbjct: 853 LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNL-------CINLFLAELLF 905
Query: 211 YAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYT 270
D I+ C HY ++ + WL +EG++L+ LLVE F E +Y
Sbjct: 906 LVGIDKTQYEIA---CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYY 962
Query: 271 IIGWGTPTVCVTVWATL--RLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGII 328
+ G+ P + V + A + R Y + CW D+ +W I GPV I+VN V ++
Sbjct: 963 LGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFI-GPVSFVIVVNLVF---LM 1018
Query: 329 VILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFEL-- 386
V L + ++S + +SS + L I L + +AF ++K ++ L
Sbjct: 1019 VTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFT 1078
Query: 387 GLGSFQGFVVAVLYCFLNGEVQAEIKR 413
+FQG + V +C L +V E +
Sbjct: 1079 TFNAFQGVFIFVFHCALQKKVHKEYSK 1105
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 79.7 bits (195), Expect = 5e-15
Identities = 88/335 (26%), Positives = 133/335 (39%), Gaps = 49/335 (14%)
Query: 137 DEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSF 196
D E + D L+V V S + + LT A IL R L IH N+
Sbjct: 2525 DASPRERLEGDLELLAVFTHVVVAVSVAALVLTAA--ILLSLRSLKSNVRGIHANVAA-- 2580
Query: 197 MLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLV 256
A+ V ++L + N + C AV + HY +S + WLF++GL+L+ + V
Sbjct: 2581 ---ALGVAELLFLLGIHRTHNQ-----LVCTAVAILLHYFFLSTFAWLFVQGLHLYRMQV 2632
Query: 257 ETFFPERRYFYWYTIIGWGTPTVCVTVWATL--RLYFDDTGCWDMNDSTALWWVIKGPVV 314
E +R +Y +GWG P V + + L Y + CW ++ L W GPVV
Sbjct: 2633 EPRNVDRGAMRFYHALGWGVPAVLLGLAVGLDPEGYGNPDFCW-ISVHEPLIWSFAGPVV 2691
Query: 315 GSIMVNFVLFIGIIVILVQKLQSPDMGGNE----------SSIYLRLARSTLLLIPLFGI 364
I++N +F L+ S G E SS L L S L L +
Sbjct: 2692 LVIVMNGTMF------LLAARTSCSTGQREAKKTSALTLRSSFLLLLLVSASWLFGLLAV 2745
Query: 365 HYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYF 424
++++ AF GL QG V +L+C LN + +A W + R
Sbjct: 2746 NHSILAFH----------YLHAGLCGLQGLAVLLLFCVLNADARA----AWMPACLGRKA 2791
Query: 425 AVDFKHRHPSLASSGVNGGTQLSILSKSSSQIRMS 459
A + P L N + L + S IR++
Sbjct: 2792 APEEARPAPGLGPGAYNN----TALFEESGLIRIT 2822
>gi|40807489 egf-like module containing, mucin-like, hormone
receptor-like sequence 1 [Homo sapiens]
Length = 886
Score = 77.8 bits (190), Expect = 2e-14
Identities = 70/264 (26%), Positives = 119/264 (45%), Gaps = 23/264 (8%)
Query: 159 VGYSTSLVTLTTAMV--ILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDS 216
VG SLV L A+ +LCR + H T ++H++L V +L A ++F+
Sbjct: 608 VGIIISLVCLVLAIATFLLCRSIRNHNT--YLHLHLCVCLLL-AKTLFLA---------G 655
Query: 217 NHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLF----TLLVETFFPERRY-FYWYTI 271
H + + C + F HY ++ +FW+ +E + LF L V +F R
Sbjct: 656 IHKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICA 715
Query: 272 IGWGTPTVCVTVWATLRL--YFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIV 329
G+G P + V + A+++ Y CW +N T W GPV I++N +L +
Sbjct: 716 FGYGLPMLVVVISASVQPQGYGMHNRCW-LNTETGFIWSFLGPVCTVIVINSLLLTWTLW 774
Query: 330 ILVQKLQSPDMGGNESSIYLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLG 389
IL Q+L S + + L + + G + + F V+ +F + +
Sbjct: 775 ILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTI-IN 833
Query: 390 SFQGFVVAVLYCFLNGEVQAEIKR 413
S QG + +++C LNG+V+ E KR
Sbjct: 834 SLQGAFIFLIHCLLNGQVREEYKR 857
>gi|119943125 G protein-coupled receptor 64 isoform 3 [Homo sapiens]
Length = 995
Score = 75.9 bits (185), Expect = 7e-14
Identities = 81/324 (25%), Positives = 143/324 (44%), Gaps = 46/324 (14%)
Query: 159 VGYSTSLVTLTTAMVILCRFRKLHCTRNF---IHMNLFVSFMLRAISVFIKDWI-LYAEQ 214
+G S + L+ +V F K+ R++ I + L + +L + + WI LY Q
Sbjct: 612 IGCGLSSIFLSVTLVTYIAFEKIR--RDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 669
Query: 215 DSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPE-RRYFYWYTIIG 273
C +V VF HY ++ ++ W+ +E +++ LV+ F R+Y + I+G
Sbjct: 670 GL---------CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVG 720
Query: 274 WGTPTVCVTVWAT-------LRLY------FDDTGCWDMNDSTALWWVIKGPVVGSIMVN 320
WG P V VT+ T L Y D CW N+ A++++ VVG V
Sbjct: 721 WGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNN--AVFYI---TVVGYFCVI 775
Query: 321 FVLFIGI-IVILVQ--KLQSPDMGGNESSIYLRLARSTLLLIPLFGI--HYTVFAFSPEN 375
F+L + + IV+LVQ +++ G + ++ RS L L GI + FA+ P N
Sbjct: 776 FLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVN 835
Query: 376 VSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSL 435
V+ + QGF + + YC + ++++WR + +
Sbjct: 836 VTFMYLFAI---FNTLQGFFIFIFYCV----AKENVRKQWRRYLCCGKLRLAENSDWSKT 888
Query: 436 ASSGVNGGTQLSILSKSSSQIRMS 459
A++G+ T +S SS+ ++ S
Sbjct: 889 ATNGLKKQTVNQGVSSSSNSLQSS 912
>gi|119943116 G protein-coupled receptor 64 isoform 2 [Homo sapiens]
Length = 1003
Score = 75.9 bits (185), Expect = 7e-14
Identities = 81/324 (25%), Positives = 143/324 (44%), Gaps = 46/324 (14%)
Query: 159 VGYSTSLVTLTTAMVILCRFRKLHCTRNF---IHMNLFVSFMLRAISVFIKDWI-LYAEQ 214
+G S + L+ +V F K+ R++ I + L + +L + + WI LY Q
Sbjct: 620 IGCGLSSIFLSVTLVTYIAFEKIR--RDYPSKILIQLCAALLLLNLVFLLDSWIALYKMQ 677
Query: 215 DSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPE-RRYFYWYTIIG 273
C +V VF HY ++ ++ W+ +E +++ LV+ F R+Y + I+G
Sbjct: 678 GL---------CISVAVFLHYFLLVSFTWMGLEAFHMYLALVKVFNTYIRKYILKFCIVG 728
Query: 274 WGTPTVCVTVWAT-------LRLY------FDDTGCWDMNDSTALWWVIKGPVVGSIMVN 320
WG P V VT+ T L Y D CW N+ A++++ VVG V
Sbjct: 729 WGVPAVVVTIILTISPDNYGLGSYGKFPNGSPDDFCWINNN--AVFYI---TVVGYFCVI 783
Query: 321 FVLFIGI-IVILVQ--KLQSPDMGGNESSIYLRLARSTLLLIPLFGI--HYTVFAFSPEN 375
F+L + + IV+LVQ +++ G + ++ RS L L GI + FA+ P N
Sbjct: 784 FLLNVSMFIVVLVQLCRIKKKKQLGAQRKTSIQDLRSIAGLTFLLGITWGFAFFAWGPVN 843
Query: 376 VSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKVNRYFAVDFKHRHPSL 435
V+ + QGF + + YC + ++++WR + +
Sbjct: 844 VTFMYLFAI---FNTLQGFFIFIFYCV----AKENVRKQWRRYLCCGKLRLAENSDWSKT 896
Query: 436 ASSGVNGGTQLSILSKSSSQIRMS 459
A++G+ T +S SS+ ++ S
Sbjct: 897 ATNGLKKQTVNQGVSSSSNSLQSS 920
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.454
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,551,759
Number of Sequences: 37866
Number of extensions: 767826
Number of successful extensions: 2212
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 36
Number of HSP's that attempted gapping in prelim test: 1998
Number of HSP's gapped (non-prelim): 109
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.