Guide to the Human Genome
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Search of human proteins with 28872770

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28872770 tRNA aspartic acid methyltransferase 1 isoform b
[Homo sapiens]
         (367 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28872770 tRNA aspartic acid methyltransferase 1 isoform b [Ho...   729   0.0  
gi|4758184 tRNA aspartic acid methyltransferase 1 isoform a [Hom...   715   0.0  
gi|28872768 tRNA aspartic acid methyltransferase 1 isoform c [Ho...   674   0.0  
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...    45   1e-04
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    45   1e-04
gi|24415404 MDN1, midasin homolog [Homo sapiens]                       38   0.016
gi|19923559 EMSY protein [Homo sapiens]                                30   2.6  
gi|50083293 coiled-coil domain containing 123 [Homo sapiens]           30   4.5  
gi|110349750 malonyl-CoA decarboxylase precursor [Homo sapiens]        29   7.6  
gi|55953087 G protein-binding protein CRFG [Homo sapiens]              28   10.0 

>gi|28872770 tRNA aspartic acid methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 367

 Score =  729 bits (1881), Expect = 0.0
 Identities = 367/367 (100%), Positives = 367/367 (100%)

Query: 1   MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI 60
           MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI
Sbjct: 1   MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI 60

Query: 61  TLEEFDRLSFDMILMSPPCQPFTRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQY 120
           TLEEFDRLSFDMILMSPPCQPFTRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQY
Sbjct: 61  TLEEFDRLSFDMILMSPPCQPFTRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQY 120

Query: 121 QEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENK 180
           QEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENK
Sbjct: 121 QEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENK 180

Query: 181 IQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVN 240
           IQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVN
Sbjct: 181 IQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVN 240

Query: 241 QYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLT 300
           QYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLT
Sbjct: 241 QYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLT 300

Query: 301 NLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAK 360
           NLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAK
Sbjct: 301 NLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAK 360

Query: 361 LIKILYE 367
           LIKILYE
Sbjct: 361 LIKILYE 367


>gi|4758184 tRNA aspartic acid methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 391

 Score =  715 bits (1846), Expect = 0.0
 Identities = 367/391 (93%), Positives = 367/391 (93%), Gaps = 24/391 (6%)

Query: 1   MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI 60
           MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI
Sbjct: 1   MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI 60

Query: 61  TLEEFDRLSFDMILMSPPCQPFTR------------------------LQKLPKYILLEN 96
           TLEEFDRLSFDMILMSPPCQPFTR                        LQKLPKYILLEN
Sbjct: 61  TLEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLHILDILPRLQKLPKYILLEN 120

Query: 97  VKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPG 156
           VKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPG
Sbjct: 121 VKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPG 180

Query: 157 QVLMEFPKIESVHPQKYAMDVENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHR 216
           QVLMEFPKIESVHPQKYAMDVENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHR
Sbjct: 181 QVLMEFPKIESVHPQKYAMDVENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHR 240

Query: 217 KNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSY 276
           KNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSY
Sbjct: 241 KNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSY 300

Query: 277 IEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGF 336
           IEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGF
Sbjct: 301 IEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGF 360

Query: 337 PEKITVKQRYRLLGNSLNVHVVAKLIKILYE 367
           PEKITVKQRYRLLGNSLNVHVVAKLIKILYE
Sbjct: 361 PEKITVKQRYRLLGNSLNVHVVAKLIKILYE 391


>gi|28872768 tRNA aspartic acid methyltransferase 1 isoform c [Homo
           sapiens]
          Length = 345

 Score =  674 bits (1740), Expect = 0.0
 Identities = 345/367 (94%), Positives = 345/367 (94%), Gaps = 22/367 (5%)

Query: 1   MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI 60
           MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI
Sbjct: 1   MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGI 60

Query: 61  TLEEFDRLSFDMILMSPPCQPFTRLQKLPKYILLENVKGFEVSSTRDLLIQTIENCGFQY 120
           TLEEFDRLSFDMILMSPPCQPFTR                      DLLIQTIENCGFQY
Sbjct: 61  TLEEFDRLSFDMILMSPPCQPFTR----------------------DLLIQTIENCGFQY 98

Query: 121 QEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENK 180
           QEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENK
Sbjct: 99  QEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENK 158

Query: 181 IQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVN 240
           IQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVN
Sbjct: 159 IQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVN 218

Query: 241 QYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLT 300
           QYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLT
Sbjct: 219 QYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLT 278

Query: 301 NLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAK 360
           NLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAK
Sbjct: 279 NLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGFPEKITVKQRYRLLGNSLNVHVVAK 338

Query: 361 LIKILYE 367
           LIKILYE
Sbjct: 339 LIKILYE 345


>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
            sapiens]
          Length = 1632

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 43/189 (22%)

Query: 4    LRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQ--------LLAK 55
            LR L+++SG GG+     ++ I +  + AI++   A + ++ N P +         LL  
Sbjct: 1155 LRTLDVFSGCGGLSEGFHQAGI-SDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKL 1213

Query: 56   TIEGITLEEFDRL-----SFDMILMSPPCQPFTRLQKL---------------------- 88
             + G T     +        +M+   PPCQ F+ + +                       
Sbjct: 1214 VMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDY 1273

Query: 89   --PKYILLENVKGFEVSSTRDLLIQTIENC----GFQYQEFLLSPTSLGIPNSRLRYFLI 142
              P++ LLENV+ F VS  R ++++    C    G+Q    +L     G+  +R R  ++
Sbjct: 1274 YRPRFFLLENVRNF-VSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIIL 1332

Query: 143  AKLQSEPLP 151
            A    E LP
Sbjct: 1333 AAAPGEKLP 1341


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
            sapiens]
          Length = 1616

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 44/189 (23%), Positives = 78/189 (41%), Gaps = 43/189 (22%)

Query: 4    LRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQ--------LLAK 55
            LR L+++SG GG+     ++ I +  + AI++   A + ++ N P +         LL  
Sbjct: 1139 LRTLDVFSGCGGLSEGFHQAGI-SDTLWAIEMWDPAAQAFRLNNPGSTVFTEDCNILLKL 1197

Query: 56   TIEGITLEEFDRL-----SFDMILMSPPCQPFTRLQKL---------------------- 88
             + G T     +        +M+   PPCQ F+ + +                       
Sbjct: 1198 VMAGETTNSRGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDY 1257

Query: 89   --PKYILLENVKGFEVSSTRDLLIQTIENC----GFQYQEFLLSPTSLGIPNSRLRYFLI 142
              P++ LLENV+ F VS  R ++++    C    G+Q    +L     G+  +R R  ++
Sbjct: 1258 YRPRFFLLENVRNF-VSFKRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIIL 1316

Query: 143  AKLQSEPLP 151
            A    E LP
Sbjct: 1317 AAAPGEKLP 1325


>gi|24415404 MDN1, midasin homolog [Homo sapiens]
          Length = 5596

 Score = 37.7 bits (86), Expect = 0.016
 Identities = 36/150 (24%), Positives = 66/150 (44%), Gaps = 6/150 (4%)

Query: 200  GKDAILFKLETAEEIHRKNQQDSDLS---VKMLKDFLEDDTDVNQYLLPPKSLLRYALLL 256
            G+ A+    E+ + +H  ++Q SD S   +  L  F +  T + Q+L    ++   A  L
Sbjct: 5421 GQIAVCSFGESVKLLHPFHEQFSDYSGSQILRLCKFQQKKTKIAQFLESVANMFAAAQQL 5480

Query: 257  --DIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIYKSLTNLSQEEQITKLLIL 314
              +I   T +  +  + G G ++EG   VL   +  +  NI+     L        +L +
Sbjct: 5481 SQNISSETAQLLLVVSDGRGLFLEGKERVLAAVQAARNANIFVIFVVLDNPSSRDSILDI 5540

Query: 315  KLRYFT-PKEIANLLGFPPEFGFPEKITVK 343
            K+  F  P E+  +  +  EF FP  I ++
Sbjct: 5541 KVPIFKGPGEMPEIRSYMEEFPFPYYIILR 5570


>gi|19923559 EMSY protein [Homo sapiens]
          Length = 1322

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 16/66 (24%), Positives = 33/66 (50%), Gaps = 1/66 (1%)

Query: 124 LLSPTSLGIPNSRLRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENKIQE 183
           ++S  + G+  S ++     +L S      AP Q+L +FPK     P++    V+ + Q+
Sbjct: 363 VMSTVAQGVSTSAIK-MASTRLPSPKSLVSAPTQILAQFPKQHQQSPKQQLYQVQQQTQQ 421

Query: 184 KNVEPN 189
           +  +P+
Sbjct: 422 QVAQPS 427


>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
          Length = 783

 Score = 29.6 bits (65), Expect = 4.5
 Identities = 27/104 (25%), Positives = 53/104 (50%), Gaps = 19/104 (18%)

Query: 141 LIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVE-NKIQEKNVEPNISFDGSIQCS 199
           L ++LQ E    +A  + LME  K+  +  QK ++ +E N + E+N              
Sbjct: 520 LKSQLQKEEEKERAEMEELME--KLTVLQAQKKSLLLEKNSLTEQN-------------- 563

Query: 200 GKDAILFKLETAEEIHRKNQQDSDLSVKMLKDFLEDDTDVNQYL 243
              A+  +LE A++I+RK+Q+  ++  K ++  + ++   +QYL
Sbjct: 564 --KALEAELERAQKINRKSQKKIEVLKKQVEKAMGNEMSAHQYL 605


>gi|110349750 malonyl-CoA decarboxylase precursor [Homo sapiens]
          Length = 493

 Score = 28.9 bits (63), Expect = 7.6
 Identities = 13/43 (30%), Positives = 25/43 (58%)

Query: 139 YFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMDVENKI 181
           +F    L  E + + +P +VL +  + E+VHP K  MD++ ++
Sbjct: 189 WFSSGFLNLERVTWHSPCEVLQKISEAEAVHPVKNWMDMKRRV 231


>gi|55953087 G protein-binding protein CRFG [Homo sapiens]
          Length = 634

 Score = 28.5 bits (62), Expect = 10.0
 Identities = 14/51 (27%), Positives = 30/51 (58%), Gaps = 3/51 (5%)

Query: 136 RLRYFLIAKLQSEPLPFQAP-GQVLMEFPKIESVHPQKYAMDVENKIQEKN 185
           R+R+F + K++     +     Q+L +FPK++ +HP  +  D+ N + +K+
Sbjct: 42  RIRHFYMRKVKFTQQNYHDRLSQILTDFPKLDDIHP--FYADLMNILYDKD 90


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,333,904
Number of Sequences: 37866
Number of extensions: 561755
Number of successful extensions: 1302
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1291
Number of HSP's gapped (non-prelim): 10
length of query: 367
length of database: 18,247,518
effective HSP length: 104
effective length of query: 263
effective length of database: 14,309,454
effective search space: 3763386402
effective search space used: 3763386402
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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