Guide to the Human Genome
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Search of human proteins with 28144908

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28144908 clarin 1 isoform a [Homo sapiens]
         (232 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28144908 clarin 1 isoform a [Homo sapiens]                         472   e-133
gi|16506281 clarin 1 isoform c [Homo sapiens]                         215   3e-56
gi|150010645 clarin 2 [Homo sapiens]                                  162   2e-40
gi|22748685 clarin 3 [Homo sapiens]                                    80   1e-15
gi|239754660 PREDICTED: hypothetical protein [Homo sapiens]            30   2.3  
gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo ...    30   2.3  
gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo ...    30   2.3  
gi|239508955 PREDICTED: hypothetical protein [Homo sapiens]            30   2.3  
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp...    28   8.7  
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp...    28   8.7  

>gi|28144908 clarin 1 isoform a [Homo sapiens]
          Length = 232

 Score =  472 bits (1214), Expect = e-133
 Identities = 232/232 (100%), Positives = 232/232 (100%)

Query: 1   MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGE 60
           MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGE
Sbjct: 1   MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGE 60

Query: 61  MQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFM 120
           MQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFM
Sbjct: 61  MQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFM 120

Query: 121 YNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKT 180
           YNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKT
Sbjct: 121 YNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKT 180

Query: 181 QSEKYTTSFWVIFFCFFVHFLNGLLIRLAGFQFPFAKSKDAETTNVAADLMY 232
           QSEKYTTSFWVIFFCFFVHFLNGLLIRLAGFQFPFAKSKDAETTNVAADLMY
Sbjct: 181 QSEKYTTSFWVIFFCFFVHFLNGLLIRLAGFQFPFAKSKDAETTNVAADLMY 232


>gi|16506281 clarin 1 isoform c [Homo sapiens]
          Length = 120

 Score =  215 bits (547), Expect = 3e-56
 Identities = 105/106 (99%), Positives = 106/106 (100%)

Query: 86  FPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLSFISG 145
           FPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLSFISG
Sbjct: 10  FPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFMYNAFGKPFETLHGPLGLYLLSFISG 69

Query: 146 SCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFWV 191
           SCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFW+
Sbjct: 70  SCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKTQSEKYTTSFWL 115


>gi|150010645 clarin 2 [Homo sapiens]
          Length = 232

 Score =  162 bits (411), Expect = 2e-40
 Identities = 81/232 (34%), Positives = 131/232 (56%)

Query: 1   MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGE 60
           MP   KK  + +A + SF+  + ++ AL  P W+   +LC+TG  LVNA+ +EL KF+G+
Sbjct: 1   MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGD 60

Query: 61  MQYGLFHGEGVRQCGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFFM 120
           + YGLF G  VRQCGLG R  +F+ FP L+K +   +HV ++L   + + L +V   F +
Sbjct: 61  IYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAI 120

Query: 121 YNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVYKT 180
            N    P+  + GP G+ L + ++G    L +  F + VK H L+E+IAN++E  + +  
Sbjct: 121 LNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVV 180

Query: 181 QSEKYTTSFWVIFFCFFVHFLNGLLIRLAGFQFPFAKSKDAETTNVAADLMY 232
             E+Y  SFW+       H  N +++ ++    P  K+K  E T  A D++Y
Sbjct: 181 VEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY 232


>gi|22748685 clarin 3 [Homo sapiens]
          Length = 226

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 51/208 (24%), Positives = 96/208 (46%), Gaps = 12/208 (5%)

Query: 1   MPSQQKKIIFCMAGVFSFACALGVVTALGTPLWIKATVLCKTGALLVNASGQELDKFMGE 60
           MP+ +K ++F  +   S    + + + LGT  WI +T+  +  A    ++G         
Sbjct: 1   MPTTKKTLMFLSSFFTSLGSFIVICSILGTQAWITSTIAVRDSA----SNGSIF------ 50

Query: 61  MQYGLFHGEGVRQC--GLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAF 118
           + YGLF GE   +   GL     +F+    L  +   ++H   ILF  + ++ +++ + F
Sbjct: 51  ITYGLFRGESSEELSHGLAEPKKKFAVLEILNNSSQKTLHSVTILFLVLSLITSLLSSGF 110

Query: 119 FMYNAFGKPFETLHGPLGLYLLSFISGSCGCLVMILFASEVKIHHLSEKIANYKEGTYVY 178
             YN+   P++T  GP G+Y  + +  S   + MILF +  + + LSE++          
Sbjct: 111 TFYNSISNPYQTFLGPTGVYTWNGLGASFVFVTMILFVANTQSNQLSEELFQMLYPATTS 170

Query: 179 KTQSEKYTTSFWVIFFCFFVHFLNGLLI 206
           K  +  Y  SFW+I     ++ +   +I
Sbjct: 171 KGTTHSYGYSFWLILLVILLNIVTVTII 198


>gi|239754660 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 221

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 91  KAIPVSIHV---NVILFSAILIVLTMVGTAFFMYNAFGKPF-ETLHGPLGLYLLSFISGS 146
           K  P+SI++    V L SA+ +      T F M     + F  T      L  +SF +G+
Sbjct: 64  KPRPLSIYIILGRVFLLSAVFLAFV---TTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 147 CGCLVMILFASEVK 160
           C  L ++L A E+K
Sbjct: 121 CAFLALVLHALEIK 134


>gi|239749194 PREDICTED: hypothetical protein XP_002346946 [Homo
           sapiens]
          Length = 221

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 91  KAIPVSIHV---NVILFSAILIVLTMVGTAFFMYNAFGKPF-ETLHGPLGLYLLSFISGS 146
           K  P+SI++    V L SA+ +      T F M     + F  T      L  +SF +G+
Sbjct: 64  KPRPLSIYIILGRVFLLSAVFLAFV---TTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 147 CGCLVMILFASEVK 160
           C  L ++L A E+K
Sbjct: 121 CAFLALVLHALEIK 134


>gi|239743274 PREDICTED: hypothetical protein XP_002342783 [Homo
           sapiens]
          Length = 221

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 91  KAIPVSIHV---NVILFSAILIVLTMVGTAFFMYNAFGKPF-ETLHGPLGLYLLSFISGS 146
           K  P+SI++    V L SA+ +      T F M     + F  T      L  +SF +G+
Sbjct: 64  KPRPLSIYIILGRVFLLSAVFLAFV---TTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 147 CGCLVMILFASEVK 160
           C  L ++L A E+K
Sbjct: 121 CAFLALVLHALEIK 134


>gi|239508955 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 221

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 7/74 (9%)

Query: 91  KAIPVSIHV---NVILFSAILIVLTMVGTAFFMYNAFGKPF-ETLHGPLGLYLLSFISGS 146
           K  P+SI++    V L SA+ +      T F M     + F  T      L  +SF +G+
Sbjct: 64  KPRPLSIYIILGRVFLLSAVFLAFV---TTFIMMPFASEFFPRTWKQNFVLACISFFTGA 120

Query: 147 CGCLVMILFASEVK 160
           C  L ++L A E+K
Sbjct: 121 CAFLALVLHALEIK 134


>gi|90403614 solute carrier family 4, sodium bicarbonate
           cotransporter, member 8 isoform a [Homo sapiens]
          Length = 1093

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 40/157 (25%), Positives = 63/157 (40%), Gaps = 23/157 (14%)

Query: 19  ACALGVVTALGTPLWIKATVLCKTGALLVNASGQ-----ELDKFMGEMQYGLFHGEGVRQ 73
           A  LGV + +G P ++ ATVL  T    +    +     E  KF+G         + V  
Sbjct: 829 AIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLG------IREQRVTG 882

Query: 74  CGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFF-MYNAFGKPFE--- 129
             +        F   +LK IP+ +   V L+     V ++ G  FF     FG P +   
Sbjct: 883 LMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMG---VSSLQGIQFFDRLKLFGMPAKHQP 939

Query: 130 ----TLHGPL-GLYLLSFISGSCGCLVMILFASEVKI 161
                 H PL  ++L + I  +C  L+ ++ AS   I
Sbjct: 940 DFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAI 976


>gi|90568034 solute carrier family 4, sodium bicarbonate
           cotransporter, member 8 isoform b [Homo sapiens]
          Length = 1044

 Score = 27.7 bits (60), Expect = 8.7
 Identities = 40/157 (25%), Positives = 63/157 (40%), Gaps = 23/157 (14%)

Query: 19  ACALGVVTALGTPLWIKATVLCKTGALLVNASGQ-----ELDKFMGEMQYGLFHGEGVRQ 73
           A  LGV + +G P ++ ATVL  T    +    +     E  KF+G         + V  
Sbjct: 829 AIMLGVCSIMGLPWFVAATVLSITHVNSLKLESECSAPGEQPKFLG------IREQRVTG 882

Query: 74  CGLGARPFRFSFFPDLLKAIPVSIHVNVILFSAILIVLTMVGTAFF-MYNAFGKPFE--- 129
             +        F   +LK IP+ +   V L+     V ++ G  FF     FG P +   
Sbjct: 883 LMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMG---VSSLQGIQFFDRLKLFGMPAKHQP 939

Query: 130 ----TLHGPL-GLYLLSFISGSCGCLVMILFASEVKI 161
                 H PL  ++L + I  +C  L+ ++ AS   I
Sbjct: 940 DFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAI 976


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.330    0.143    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,980,389
Number of Sequences: 37866
Number of extensions: 313447
Number of successful extensions: 847
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 842
Number of HSP's gapped (non-prelim): 10
length of query: 232
length of database: 18,247,518
effective HSP length: 99
effective length of query: 133
effective length of database: 14,498,784
effective search space: 1928338272
effective search space used: 1928338272
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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