Search of human proteins with 27894330

Search of human proteins with 27894330

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27894330 interleukin 1, alpha proprotein [Homo sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27894330 interleukin 1, alpha proprotein [Homo sapiens]            539   e-153
gi|10835145 interleukin 1, beta proprotein [Homo sapiens]              47   1e-05
gi|94681046 cyclin M4 [Homo sapiens]                                   30   1.7  
gi|23397659 alpha/beta hydrolase domain containing protein 2 [Ho...    30   1.7  
gi|23397661 alpha/beta hydrolase domain containing protein 2 [Ho...    30   1.7  
gi|51243032 oxysterol-binding protein-like protein 8 isoform b [...    30   2.2  
gi|18079218 oxysterol-binding protein-like protein 8 isoform a [...    30   2.2  
gi|148540038 hypothetical protein LOC130355 [Homo sapiens]             30   2.2  
gi|13470094 apolipoprotein L5 [Homo sapiens]                           28   6.5  
gi|18093112 ABT1-associated protein [Homo sapiens]                     28   8.5  

>gi|27894330 interleukin 1, alpha proprotein [Homo sapiens]
          Length = 271

 Score =  539 bits (1388), Expect = e-153
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETS 60
           MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETS
Sbjct: 1   MAKVPDMFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETS 60

Query: 61  KTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLS 120
           KTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLS
Sbjct: 61  KTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFLS 120

Query: 121 NVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKI 180
           NVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKI
Sbjct: 121 NVKYNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKI 180

Query: 181 TVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHP 240
           TVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHP
Sbjct: 181 TVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKNYFTSVAHP 240

Query: 241 NLFIATKQDYWVCLAGGPPSITDFQILENQA 271
           NLFIATKQDYWVCLAGGPPSITDFQILENQA
Sbjct: 241 NLFIATKQDYWVCLAGGPPSITDFQILENQA 271


>gi|10835145 interleukin 1, beta proprotein [Homo sapiens]
          Length = 269

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 69/275 (25%), Positives = 115/275 (41%), Gaps = 24/275 (8%)

Query: 1   MAKVPDMFEDLKNCYSENEED-SSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISET 59
           MA+VP++  ++   YS NE+D     D     + SF  +   PL     D  + L IS+ 
Sbjct: 1   MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPL-----DGGIQLRISDH 55

Query: 60  SKTSKLTFKESMVVVATNGKVLKKRRLSLSQSITDDDLEAIANDSEEEIIKPRSAPFSFL 119
             +    F+++  VV    K L+K  +   Q+  ++DL          I +     F   
Sbjct: 56  HYSK--GFRQAASVVVAMDK-LRKMLVPCPQTFQENDLSTFF----PFIFEEEPIFFDTW 108

Query: 120 SNVKY-NFMRIIKYEFILNDALNQSIIRANDQYLTAAAL--HNLDEAVKFDMGAYKSSKD 176
            N  Y +   +      L D+  +S++ +    L A  L   ++++ V F M   +  + 
Sbjct: 109 DNEAYVHDAPVRSLNCTLRDSQQKSLVMSGPYELKALHLQGQDMEQQVVFSMSFVQGEES 168

Query: 177 DAKITVILRISKTQLYVT-AQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHGTKN--Y 233
           + KI V L + +  LY++    +D+P L  E  + PK     +    F +      N   
Sbjct: 169 NDKIPVALGLKEKNLYLSCVLKDDKPTLQLESVD-PKNYPKKKMEKRFVFNKIEINNKLE 227

Query: 234 FTSVAHPNLFIATKQ--DYWVCLAG--GPPSITDF 264
           F S   PN +I+T Q  +  V L G  G   ITDF
Sbjct: 228 FESAQFPNWYISTSQAENMPVFLGGTKGGQDITDF 262


>gi|94681046 cyclin M4 [Homo sapiens]
          Length = 775

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 16/85 (18%), Positives = 38/85 (44%), Gaps = 2/85 (2%)

Query: 124 YNFMRIIKYEFILNDALNQSIIRANDQYLTAAALHNLDEAVKFDMGAYKSSKDDAKITVI 183
           Y  + ++  E ++ + +   I+  +D Y    +   + E  K D  A+K + ++ K+ + 
Sbjct: 488 YEVLGLVTLEDVIEEIIKSEILDESDMYTDNRSRKRVSEKNKRDFSAFKDADNELKVKIS 547

Query: 184 --LRISKTQLYVTAQDEDQPVLLKE 206
             L ++  +   T   +  P L+ E
Sbjct: 548 PQLLLAAHRFLATEVSQFSPSLISE 572


>gi|23397659 alpha/beta hydrolase domain containing protein 2 [Homo
           sapiens]
          Length = 425

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 6/81 (7%)

Query: 153 TAAALHNLDEAVKFDMGAYKSSKD----DAKITVILRISKTQLYVTAQDEDQPVLLKEMP 208
           TA +L  +D+ V      Y S K+    ++ +  + RI    + V A D+  P++ + + 
Sbjct: 296 TATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADD--PLVHESLL 353

Query: 209 EIPKTITGSETNLLFFWETHG 229
            IPK+++    N++F    HG
Sbjct: 354 TIPKSLSEKRENVMFVLPLHG 374


>gi|23397661 alpha/beta hydrolase domain containing protein 2 [Homo
           sapiens]
          Length = 425

 Score = 30.4 bits (67), Expect = 1.7
 Identities = 21/81 (25%), Positives = 40/81 (49%), Gaps = 6/81 (7%)

Query: 153 TAAALHNLDEAVKFDMGAYKSSKD----DAKITVILRISKTQLYVTAQDEDQPVLLKEMP 208
           TA +L  +D+ V      Y S K+    ++ +  + RI    + V A D+  P++ + + 
Sbjct: 296 TATSLMQIDDNVMRKFHGYNSLKEYYEEESCMRYLHRIYVPLMLVNAADD--PLVHESLL 353

Query: 209 EIPKTITGSETNLLFFWETHG 229
            IPK+++    N++F    HG
Sbjct: 354 TIPKSLSEKRENVMFVLPLHG 374


>gi|51243032 oxysterol-binding protein-like protein 8 isoform b
           [Homo sapiens]
          Length = 847

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 17/96 (17%)

Query: 8   FEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTF 67
           FE  K   S+N+++SS    LS+++      S   L+ G        S  ++S +SKLT 
Sbjct: 32  FERGKEDISQNKDESS----LSMSKSK----SESKLYNG--------SEKDSSTSSKLTK 75

Query: 68  KESMVVVATNGKVLKKRRL-SLSQSITDDDLEAIAN 102
           KES+ V   N +  KKR    L  +ITD  +  +A+
Sbjct: 76  KESLKVQKKNYREEKKRATKELLSTITDPSVIVMAD 111


>gi|18079218 oxysterol-binding protein-like protein 8 isoform a
           [Homo sapiens]
          Length = 889

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 31/96 (32%), Positives = 48/96 (50%), Gaps = 17/96 (17%)

Query: 8   FEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSVSLSISETSKTSKLTF 67
           FE  K   S+N+++SS    LS+++      S   L+ G        S  ++S +SKLT 
Sbjct: 74  FERGKEDISQNKDESS----LSMSKSK----SESKLYNG--------SEKDSSTSSKLTK 117

Query: 68  KESMVVVATNGKVLKKRRL-SLSQSITDDDLEAIAN 102
           KES+ V   N +  KKR    L  +ITD  +  +A+
Sbjct: 118 KESLKVQKKNYREEKKRATKELLSTITDPSVIVMAD 153


>gi|148540038 hypothetical protein LOC130355 [Homo sapiens]
          Length = 126

 Score = 30.0 bits (66), Expect = 2.2
 Identities = 23/64 (35%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 171 YKSSKDDA-KITVILRISKTQLYVTAQDEDQPVLLKEMPEIPKTITGSETNLLFFWETHG 229
           +++ K DA KI      SKT   V + ++D+ +LLKE   +      SET + FF E   
Sbjct: 56  FRNYKYDALKIIHQAHKSKTNELVLSLEDDERLLLKEDSTLKAAGIASETEIAFFCE-ED 114

Query: 230 TKNY 233
            KNY
Sbjct: 115 YKNY 118


>gi|13470094 apolipoprotein L5 [Homo sapiens]
          Length = 433

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 21/69 (30%), Positives = 37/69 (53%), Gaps = 9/69 (13%)

Query: 7   MFEDLKNCYSENEEDSSSIDHLSLNQKSFYHVSYGPLHEGCMDQSV---SLSISETSKTS 63
           +FE+L  C    ++DS    +LS  +K F  +SY PLH+  ++Q++   +    +   T 
Sbjct: 78  LFEELMRC----DKDSMPDGNLSEEEKLF--LSYFPLHKFELEQNIKELNTLADQVDTTH 131

Query: 64  KLTFKESMV 72
           +L  K S+V
Sbjct: 132 ELLTKTSLV 140


>gi|18093112 ABT1-associated protein [Homo sapiens]
          Length = 851

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 19/88 (21%), Positives = 39/88 (44%), Gaps = 5/88 (5%)

Query: 22  SSSIDHLSLNQKSFYHVSYGPLHEGCMD-----QSVSLSISETSKTSKLTFKESMVVVAT 76
           +  +  + +N+KS      G   E  ++       ++L + +  + SK  F  + +V   
Sbjct: 673 AEEVKQIGINKKSVKSAKDGTSPEEEIEIERQKAEMALLMMDEDEDSKKHFNYNKIVEHQ 732

Query: 77  NGKVLKKRRLSLSQSITDDDLEAIANDS 104
           N    KK++L   + + +DD E   ND+
Sbjct: 733 NLSKKKKKQLMKKKELIEDDFEVNVNDA 760


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,439,154
Number of Sequences: 37866
Number of extensions: 362367
Number of successful extensions: 1121
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1117
Number of HSP's gapped (non-prelim): 10
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.