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Search of human proteins with 27436871
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27436871 carboxypeptidase O [Homo sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27436871 carboxypeptidase O [Homo sapiens] 781 0.0
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 306 1e-83
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 306 3e-83
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 304 1e-82
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 293 1e-79
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 253 3e-67
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 242 3e-64
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 234 1e-61
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 213 2e-55
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 213 2e-55
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 212 5e-55
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 146 3e-35
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 143 2e-34
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 49 1e-05
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 35 0.11
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 34 0.24
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 34 0.24
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 34 0.24
gi|31657119 carboxypeptidase 2, cytosolic [Homo sapiens] 34 0.24
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 33 0.32
gi|153792148 threonine synthase-like 1 [Homo sapiens] 33 0.32
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 33 0.42
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 33 0.42
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 33 0.42
gi|24307911 acid sphingomyelinase-like phosphodiesterase 3A [Hom... 32 1.2
gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens] 30 2.7
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 29 7.8
gi|93102361 palladin [Homo sapiens] 29 7.8
gi|21361659 importin 9 [Homo sapiens] 29 7.8
gi|13775238 plasmalemma vesicle associated protein [Homo sapiens] 29 7.8
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 781 bits (2017), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWM 60
MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWM
Sbjct: 1 MKPLLETLYLLGMLVPGGLGYDRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWM 60
Query: 61 REISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQW 120
REISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQW
Sbjct: 61 REISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQW 120
Query: 121 FVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGT 180
FVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGT
Sbjct: 121 FVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGT 180
Query: 181 DLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQ 240
DLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQ
Sbjct: 181 DLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQ 240
Query: 241 LILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARD 300
LILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARD
Sbjct: 241 LILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSADILYASSGSSRDWARD 300
Query: 301 IGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGRVTSA 360
IGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGRVTSA
Sbjct: 301 IGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDVYAKHWHSDSAGRVTSA 360
Query: 361 TMLLGLLVSCMSLL 374
TMLLGLLVSCMSLL
Sbjct: 361 TMLLGLLVSCMSLL 374
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 306 bits (785), Expect = 1e-83
Identities = 141/293 (48%), Positives = 194/293 (66%), Gaps = 1/293 (0%)
Query: 45 YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMD 104
+SY Y+ I W ++++ + ++++ +G T+E +Y LK+ + +G K I+MD
Sbjct: 114 HSYEKYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGK-AGQNKPAIFMD 172
Query: 105 CGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL 164
CG HAREWI+PAFCQWFV+E ++ + + +LL LDFYVLPVLNIDGYIYTWT R
Sbjct: 173 CGFHAREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRF 232
Query: 165 WRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224
WRK+RS H +C GTD NRNF+A WC IGASRN D+T+CG SE ETKA+A FI +
Sbjct: 233 WRKTRSTHTGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRN 292
Query: 225 KKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSA 284
K I +LT+HSY Q+++ PY Y N+ E+ + + L + +GT Y G A
Sbjct: 293 KLSSIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGA 352
Query: 285 DILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAV 337
+Y ++G S DWA D GI +S+TFELRD+G YGF+LPE+QI+ TCEET A+
Sbjct: 353 TTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI 405
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 306 bits (783), Expect = 3e-83
Identities = 145/314 (46%), Positives = 205/314 (65%), Gaps = 3/314 (0%)
Query: 29 RQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYL 88
+Q+I + +VSP + +Y Y YH + EIY W+ I+E++ +++T+ +G ++E +P+Y L
Sbjct: 103 QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVL 161
Query: 89 KISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLP 148
K+S K IW+DCGIHAREWI+PAFC WF+ I Q + LLR +DFYV+P
Sbjct: 162 KVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMP 221
Query: 149 VLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNF-NASWCSIGASRNCQDQTFCGT 207
V+N+DGY Y+W +R+WRK+RS + N C GTDLNRNF + WC GAS + +T+CG
Sbjct: 222 VVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGL 281
Query: 208 GPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAA 267
P SEPE KAVASF+ + I +++MHSY Q I+ PY YT++KS +H E+ V +A
Sbjct: 282 YPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV 341
Query: 268 NAL-KAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQI 326
A+ K T Y G ++ LY + G DW D+GI +S+T ELRD+GTYGF+LPE I
Sbjct: 342 RAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYI 401
Query: 327 QPTCEETMEAVLSV 340
+PTC E AV +
Sbjct: 402 KPTCREAFAAVSKI 415
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 304 bits (778), Expect = 1e-82
Identities = 139/300 (46%), Positives = 196/300 (65%), Gaps = 1/300 (0%)
Query: 41 SLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI 100
SL Y+Y +YH + EI WM +++ + ++ +G +YE ++ LK+ + S K+
Sbjct: 130 SLSGYNYEVYHSLEEIQNWMHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRS-RLKRA 188
Query: 101 IWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWT 160
+W+DCGIHAREWI PAFCQWFVKE L +K + ++RK+L +L FY++PV N+DGY ++WT
Sbjct: 189 VWIDCGIHAREWIGPAFCQWFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWT 248
Query: 161 TDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVAS 220
DR WRK+RS ++ C G D NRN+ WC GAS + D T+CG P SEPE KAVA+
Sbjct: 249 NDRFWRKTRSRNSRFRCRGVDANRNWKVKWCDEGASMHPCDDTYCGPFPESEPEVKAVAN 308
Query: 221 FIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRV 280
F+ + I +L+ H+Y Q++L PY Y N + KA NAL++ YG YR
Sbjct: 309 FLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATIPNFRCVESAAYKAVNALQSVYGVRYRY 368
Query: 281 GSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSV 340
G ++ LY SSGSS DWA GIP+++ FELRD+G +GF+LPE I+PTC ETM AV ++
Sbjct: 369 GPASTTLYVSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNI 428
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 293 bits (751), Expect = 1e-79
Identities = 137/293 (46%), Positives = 195/293 (66%), Gaps = 1/293 (0%)
Query: 45 YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMD 104
+SY Y+ +I W ++ +KY E+V++ +G T E +P+Y LKI + + +K I+ D
Sbjct: 114 HSYAKYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNER-RKAIFTD 172
Query: 105 CGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL 164
CGIHAREW++PAFCQWFV + + + N + KLL ++FY+LPV N+DGYI++WT +R+
Sbjct: 173 CGIHAREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRM 232
Query: 165 WRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224
WRK+RS + N C GTDLNRNFNASW SI + + + G+ P SE ETKAV +FI S
Sbjct: 233 WRKNRSKNQNSKCIGTDLNRNFNASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRS 292
Query: 225 KKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSA 284
++I ++T HSY Q++L PYGYT NH ++ +V + + L +Y T Y G
Sbjct: 293 HLNEIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVLSTRYETRYIYGPIE 352
Query: 285 DILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAV 337
+Y SGSS DWA D+GI ++ FELRD G +GF+LPE++I+PTC ETM AV
Sbjct: 353 STIYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAV 405
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 253 bits (645), Expect = 3e-67
Identities = 125/304 (41%), Positives = 190/304 (62%), Gaps = 1/304 (0%)
Query: 41 SLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI 100
S ++Y YH + IY M I+ + ++ + +G ++E PMY LK S G +
Sbjct: 114 SSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPA 173
Query: 101 IWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWT 160
+W++ GIH+REWI+ A W ++I+ +++ + +I +L +D ++LPV N DGY+YT T
Sbjct: 174 VWLNAGIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQT 233
Query: 161 TDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVAS 220
+RLWRK+RS + +C G D NRN+NAS+ GAS N + + G SE E K+V
Sbjct: 234 QNRLWRKTRSRNPGSSCIGADPNRNWNASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD 293
Query: 221 FIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRV 280
FI+ K + F+ +HSY QL++ PYGY+ K+ + E+ +V + AA AL + GT Y+V
Sbjct: 294 FIQ-KHGNFKGFIDLHSYSQLLMYPYGYSVKKAPDAEELDKVARLAAKALASVSGTEYQV 352
Query: 281 GSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSV 340
G + +Y +SGSS DWA D GI F++TFELRD+GTYGF+LP QI PT EET + ++
Sbjct: 353 GPTCTTVYPASGSSIDWAYDNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTI 412
Query: 341 LDDV 344
++ V
Sbjct: 413 MEHV 416
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 242 bits (618), Expect = 3e-64
Identities = 119/300 (39%), Positives = 185/300 (61%), Gaps = 3/300 (1%)
Query: 45 YSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMD 104
+++ YH + EI + M + ++ +V++ +G ++E PM LK S +G K IW+D
Sbjct: 118 FNFGAYHTLEEISQEMDNLVAEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLD 175
Query: 105 CGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL 164
GIHAREW+ A W +I+ ++ + SI +L LD ++LPV N DGY+++ T +R+
Sbjct: 176 AGIHAREWVTQATALWTANKIVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRM 235
Query: 165 WRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224
WRK+RS + C G D NRN++A + GAS N ++ G SE E K++ FI+S
Sbjct: 236 WRKTRSKVSGSLCVGVDPNRNWDAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKS 295
Query: 225 KKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRVGSSA 284
+ F+T+HSY QL++ PYGY K + E+ +V QKAA +L++ +GT Y+VG
Sbjct: 296 H-GKVKAFITLHSYSQLLMFPYGYKCTKLDDFDELSEVAQKAAQSLRSLHGTKYKVGPIC 354
Query: 285 DILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSVLDDV 344
++Y +SG S DW+ D GI +S+ FELRD+G YGF+LP QI PT EET + ++++ V
Sbjct: 355 SVIYQASGGSIDWSYDYGIKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 234 bits (596), Expect = 1e-61
Identities = 117/302 (38%), Positives = 186/302 (61%), Gaps = 2/302 (0%)
Query: 41 SLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI 100
S +T++Y YH + EIY+++ + + +V++ +G TYE P+Y LK S G+ +
Sbjct: 113 STDTFNYATYHTLEEIYDFLDLLVAENPHLVSKIQIGNTYEGRPIYVLKFST-GGSKRPA 171
Query: 101 IWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWT 160
IW+D GIH+REW+ A WF K+I Q++ +++ +L LD ++ V N DG+ +T +
Sbjct: 172 IWIDTGIHSREWVTQASGVWFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHS 231
Query: 161 TDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVAS 220
T+R+WRK+RS C G D NRN++A + GAS N +T+ G SE E K++
Sbjct: 232 TNRMWRKTRSHTAGSLCIGVDPNRNWDAGFGLSGASSNPCSETYHGKFANSEVEVKSIVD 291
Query: 221 FIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAANALKAKYGTNYRV 280
F++ +I F+++HSY QL++ PYGY + E+ Q+ + A AL + YGT +
Sbjct: 292 FVKDH-GNIKAFISIHSYSQLLMYPYGYKTEPVPDQDELDQLSKAAVTALASLYGTKFNY 350
Query: 281 GSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSV 340
GS +Y +SGS+ DW GI +S+TFELRD+G YGF+LP +QI PT +ET A+L++
Sbjct: 351 GSIIKAIYQASGSTIDWTYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTI 410
Query: 341 LD 342
++
Sbjct: 411 ME 412
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 213 bits (542), Expect = 2e-55
Identities = 109/318 (34%), Positives = 181/318 (56%), Gaps = 2/318 (0%)
Query: 25 LAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHP 84
L + RQ + S ++SY+ YH + EIY W+ ++ ++V++ +G ++E
Sbjct: 114 LDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQS 173
Query: 85 MYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDF 144
+ LK S G+ IW+D GIH+REWI A W +I+ ++ + + +L +D
Sbjct: 174 ILVLKFST-GGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDI 232
Query: 145 YVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTF 204
++ V N DG+ +T + +RLWRK++S C G DLNRN+ + + G++ N +T+
Sbjct: 233 FIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETY 292
Query: 205 CGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQ 264
G P SEPE A+ +FI + + +++HSY Q+++ PYG SN E+ + +
Sbjct: 293 HGPSPQSEPEVAAIVNFITAH-GNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAK 351
Query: 265 KAANALKAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEA 324
A AL +G Y GS + LY +SG + DWA D GI ++++FELRD+G YGF+LP
Sbjct: 352 DAVEALYKVHGIEYIFGSISTTLYVASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPAT 411
Query: 325 QIQPTCEETMEAVLSVLD 342
QI PT +ET A+ ++++
Sbjct: 412 QIIPTAQETWMALRTIME 429
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 213 bits (542), Expect = 2e-55
Identities = 109/318 (34%), Positives = 181/318 (56%), Gaps = 2/318 (0%)
Query: 25 LAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHP 84
L + RQ + S ++SY+ YH + EIY W+ ++ ++V++ +G ++E
Sbjct: 114 LDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQS 173
Query: 85 MYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDF 144
+ LK S G+ IW+D GIH+REWI A W +I+ ++ + + +L +D
Sbjct: 174 ILVLKFST-GGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDI 232
Query: 145 YVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTF 204
++ V N DG+ +T + +RLWRK++S C G DLNRN+ + + G++ N +T+
Sbjct: 233 FIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETY 292
Query: 205 CGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQ 264
G P SEPE A+ +FI + + +++HSY Q+++ PYG SN E+ + +
Sbjct: 293 HGPSPQSEPEVAAIVNFITAH-GNFKALISIHSYSQMLMYPYGRLLEPVSNQRELYDLAK 351
Query: 265 KAANALKAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEA 324
A AL +G Y GS + LY +SG + DWA D GI ++++FELRD+G YGF+LP
Sbjct: 352 DAVEALYKVHGIEYIFGSISTTLYVASGITVDWAYDSGIKYAFSFELRDTGQYGFLLPAT 411
Query: 325 QIQPTCEETMEAVLSVLD 342
QI PT +ET A+ ++++
Sbjct: 412 QIIPTAQETWMALRTIME 429
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 212 bits (539), Expect = 5e-55
Identities = 109/282 (38%), Positives = 158/282 (56%), Gaps = 40/282 (14%)
Query: 29 RQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYL 88
+Q+I + +VSP + +Y Y YH + EIY W+ I+E++ +++T+ +G ++E +P+Y L
Sbjct: 103 QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVL 161
Query: 89 KISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLP 148
K+S K IW+DCGIHAREWI+PAFC WF+
Sbjct: 162 KVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH------------------------ 197
Query: 149 VLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNAS-WCSIGASRNCQDQTFCGT 207
+R+WRK+RS + N C GTDLNRNF + WC GAS + +T+CG
Sbjct: 198 -------------NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGL 244
Query: 208 GPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAA 267
P SEPE KAVASF+ + I +++MHSY Q I+ PY YT++KS +H E+ V +A
Sbjct: 245 YPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV 304
Query: 268 NAL-KAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYT 308
A+ K T Y G ++ LY + G DW D+GI +S T
Sbjct: 305 RAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSVT 346
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 146 bits (369), Expect = 3e-35
Identities = 60/136 (44%), Positives = 92/136 (67%), Gaps = 1/136 (0%)
Query: 60 MREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQ 119
M +++ + ++ +G +YE ++ LK+ + S K+ +W+DCGIHAREWI PAFCQ
Sbjct: 1 MHHLNKTHSGLIHMFSIGRSYEGRSLFILKLGRRS-RLKRAVWIDCGIHAREWIGPAFCQ 59
Query: 120 WFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFG 179
WFVKE L +K + ++RK+L +L FY++PV N+DGY ++WT DR WRK+RS ++ C G
Sbjct: 60 WFVKEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRG 119
Query: 180 TDLNRNFNASWCSIGA 195
D NRN+ WC + +
Sbjct: 120 VDANRNWKVKWCDVSS 135
Score = 68.9 bits (167), Expect = 7e-12
Identities = 31/51 (60%), Positives = 40/51 (78%)
Query: 290 SSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQIQPTCEETMEAVLSV 340
SSGSS DWA GIP+++ FELRD+G +GF+LPE I+PTC ETM AV ++
Sbjct: 134 SSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNI 184
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 143 bits (361), Expect = 2e-34
Identities = 74/236 (31%), Positives = 129/236 (54%), Gaps = 2/236 (0%)
Query: 25 LAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHP 84
L + RQ + S ++SY+ YH + EIY W+ ++ ++V++ +G ++E
Sbjct: 114 LDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNFVMEHSDIVSKIQIGNSFENQS 173
Query: 85 MYYLKISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDF 144
+ LK S G+ IW+D GIH+REWI A W +I+ ++ + + +L +D
Sbjct: 174 ILVLKFST-GGSRHPAIWIDTGIHSREWITHATGIWTANKIVSDYGKDRVLTDILNAMDI 232
Query: 145 YVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTF 204
++ V N DG+ +T + +RLWRK++S C G DLNRN+ + + G++ N +T+
Sbjct: 233 FIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLNRNWKSGFGGNGSNSNPCSETY 292
Query: 205 CGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMI 260
G P SEPE A+ +FI + + +++HSY Q+++ PYG SN E++
Sbjct: 293 HGPSPQSEPEVAAIVNFI-TAHGNFKALISIHSYSQMLMYPYGRLLEPVSNQRELM 347
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 48.5 bits (114), Expect = 1e-05
Identities = 43/178 (24%), Positives = 80/178 (44%), Gaps = 22/178 (12%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSG--NPKKIIWMDCG- 106
+H ++ ++R + +Y + + LG + E+ +Y ++IS G P + + G
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
Query: 107 IHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLWR 166
+H E + ++ + +N + + L+ N +++P +N DGY + D +
Sbjct: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSISV 622
Query: 167 KSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIES 224
R+ NN DLNRNF DQ T P ++PET AV S+++S
Sbjct: 623 IGRNNSNN-----FDLNRNF-------------PDQFVQITDP-TQPETIAVMSWMKS 661
Score = 40.8 bits (94), Expect = 0.002
Identities = 58/258 (22%), Positives = 97/258 (37%), Gaps = 52/258 (20%)
Query: 22 DRSLAQHRQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYE 81
D S + ++ +S S +L Y Y+ Y ++ E++R + Y + LG + E
Sbjct: 908 DLSAENGLESLMLRSSSNLALALYRYHSYK---DLSEFLRGLVMNYPHITNLTNLGQSTE 964
Query: 82 THPMYYLKISQPSG-----NPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIR 136
++ L+IS PK I GIH + + + N+K N ++
Sbjct: 965 YRHIWSLEISNKPNVSEPEEPK--IRFVAGIHGNAPVGTELLLALAEFLCLNYKKNPAVT 1022
Query: 137 KLLRNLDFYVLPVLNIDGYIYTWTTDRLWRKS-RSPHNNGTCFGTDLNRNFNASWCSIGA 195
+L+ ++P LN DG +R K S G DL+ +F
Sbjct: 1023 QLVDRTRIVIVPSLNPDG------RERAQEKDCTSKIGQTNARGKDLDTDF--------- 1067
Query: 196 SRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYG----YTKN 251
T S+PETKA+ + K+D L + + L+ PY +N
Sbjct: 1068 -----------TNNASQPETKAIIENLIQKQDFSLS-VALDGGSMLVTYPYDKPVQTVEN 1115
Query: 252 K----------SSNHPEM 259
K ++NHP M
Sbjct: 1116 KETLKHLASLYANNHPSM 1133
Score = 28.9 bits (63), Expect = 7.8
Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 18/125 (14%)
Query: 107 IHAREWIAPAFCQWFVKEILQNHK-DNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLW 165
+H E ++ + +E+ ++ + + +LL D Y+LP LN DG+ D +
Sbjct: 138 MHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGF 197
Query: 166 RKSRSPHNNG--TCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSE--PETKAVASF 221
+G G DLNR+F DQ G P + PE +A+ +
Sbjct: 198 GDGGPSGASGRDNSRGRDLNRSF-------------PDQFSTGEPPALDEVPEVRALIEW 244
Query: 222 IESKK 226
I K
Sbjct: 245 IRRNK 249
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/144 (22%), Positives = 59/144 (40%), Gaps = 12/144 (8%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPK---KIIWMDCG 106
+H E+ + M+ ++E + + +G +++ +Y ++IS G + G
Sbjct: 318 HHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIAG 377
Query: 107 IHAREWIAPAFCQWFVKEILQNH-KDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRL- 164
H E + V+ + Q + N+ I L+ +VLP LN DGY +
Sbjct: 378 AHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEGGSEL 437
Query: 165 --WRKSRSPHNNGTCFGTDLNRNF 186
W R H+ G D+N NF
Sbjct: 438 GGWSLGRWTHD-----GIDINNNF 456
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 33.9 bits (76), Expect = 0.24
Identities = 34/182 (18%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQ-----PSGNPK-KIIWM 103
YH + +++ +++ Y V H +G + + ++ L + + G P+ K +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV-- 79
Query: 104 DCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDR 163
+H E + + ++ + + I L+ + +++P +N DG+ D
Sbjct: 80 -ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
Query: 164 LWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIE 223
+ R +N DLNRNF ++ SR +PET AV +++
Sbjct: 139 YYSIGRENYNQ-----YDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLK 179
Query: 224 SK 225
++
Sbjct: 180 TE 181
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 33.9 bits (76), Expect = 0.24
Identities = 34/182 (18%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQ-----PSGNPK-KIIWM 103
YH + +++ +++ Y V H +G + + ++ L + + G P+ K +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV-- 79
Query: 104 DCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDR 163
+H E + + ++ + + I L+ + +++P +N DG+ D
Sbjct: 80 -ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
Query: 164 LWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIE 223
+ R +N DLNRNF ++ SR +PET AV +++
Sbjct: 139 YYSIGRENYNQ-----YDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLK 179
Query: 224 SK 225
++
Sbjct: 180 TE 181
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 33.9 bits (76), Expect = 0.24
Identities = 34/182 (18%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQ-----PSGNPK-KIIWM 103
YH + +++ +++ Y V H +G + + ++ L + + G P+ K +
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYV-- 79
Query: 104 DCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDR 163
+H E + + ++ + + I L+ + +++P +N DG+ D
Sbjct: 80 -ANMHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDC 138
Query: 164 LWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQDQTFCGTGPVSEPETKAVASFIE 223
+ R +N DLNRNF ++ SR +PET AV +++
Sbjct: 139 YYSIGRENYNQ-----YDLNRNFPDAFEYNNVSR--------------QPETVAVMKWLK 179
Query: 224 SK 225
++
Sbjct: 180 TE 181
>gi|31657119 carboxypeptidase 2, cytosolic [Homo sapiens]
Length = 902
Score = 33.9 bits (76), Expect = 0.24
Identities = 27/78 (34%), Positives = 38/78 (48%), Gaps = 10/78 (12%)
Query: 85 MYYLKISQPSGNP-----KKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLL 139
+Y L I+ PS P KK + + +H E + W +K L NS +LL
Sbjct: 434 VYLLTITNPSQTPQEAAAKKAVVLSARVHPGE----SNGSWVMKGFLDFILSNSPDAQLL 489
Query: 140 RNLD-FYVLPVLNIDGYI 156
R++ F VLP+LN DG I
Sbjct: 490 RDIFVFKVLPMLNPDGVI 507
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 33.5 bits (75), Expect = 0.32
Identities = 32/147 (21%), Positives = 63/147 (42%), Gaps = 18/147 (12%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPK---KIIWMDCG 106
+H + + M+++ E+ + + +G +Y+ +Y +++S G + + G
Sbjct: 299 HHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVAG 358
Query: 107 IHAREWIAPAFC----QWFVKEILQNHKDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTD 162
+H E + Q+ E L+ N + +LL + ++LP +N DGY +
Sbjct: 359 MHGNEALGRELLLLLMQFLCHEFLRG---NPRVTRLLSEMRIHLLPSMNPDGYEIAYHRG 415
Query: 163 RL---WRKSRSPHNNGTCFGTDLNRNF 186
W + R NN + DLN NF
Sbjct: 416 SELVGWAEGR--WNNQS---IDLNHNF 437
>gi|153792148 threonine synthase-like 1 [Homo sapiens]
Length = 743
Score = 33.5 bits (75), Expect = 0.32
Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 5/99 (5%)
Query: 141 NLDFYVLPVLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNASWCSIGASRNCQ 200
NL+ ++ + N DG + T +RL +S+ L ++F A WCS G
Sbjct: 571 NLERHLHLMANKDGQLMTELFNRL--ESQHHFQIEKALVEKLQQDFVADWCSEGECLAAI 628
Query: 201 DQTFCGTGPVSEPET---KAVASFIESKKDDILCFLTMH 236
+ T+ +G + +P T K VA ++ K ++ T H
Sbjct: 629 NSTYNTSGYILDPHTAVAKVVADRVQDKTCPVIISSTAH 667
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 33.1 bits (74), Expect = 0.42
Identities = 37/217 (17%), Positives = 86/217 (39%), Gaps = 23/217 (10%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI---IWMDCG 106
+H ++ +R + + V + +G +++ + ++ S G + + + +
Sbjct: 50 HHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGN 109
Query: 107 IHAREWIAPAFCQWFVKEILQNHK-DNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLW 165
IH E + + + + N I++LL ++LP +N DGY +
Sbjct: 110 IHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGY 169
Query: 166 RKSRSPHNNGTCFGTDLNRNF---NASWCSIGASRNCQDQTFCGTGPVSE--------PE 214
S N DLNRNF + + + +R + P+ + PE
Sbjct: 170 NGWTSGRQNAQ--NLDLNRNFPDLTSEYYRLAETRGARSDHI----PIPQHYWWGKVAPE 223
Query: 215 TKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKN 251
TKA+ ++++ + ++H ++ P+ ++K+
Sbjct: 224 TKAIMKWMQT--IPFVLSASLHGGDLVVSYPFDFSKH 258
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 33.1 bits (74), Expect = 0.42
Identities = 37/217 (17%), Positives = 86/217 (39%), Gaps = 23/217 (10%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI---IWMDCG 106
+H ++ +R + + V + +G +++ + ++ S G + + + +
Sbjct: 176 HHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGN 235
Query: 107 IHAREWIAPAFCQWFVKEILQNHK-DNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLW 165
IH E + + + + N I++LL ++LP +N DGY +
Sbjct: 236 IHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGY 295
Query: 166 RKSRSPHNNGTCFGTDLNRNF---NASWCSIGASRNCQDQTFCGTGPVSE--------PE 214
S N DLNRNF + + + +R + P+ + PE
Sbjct: 296 NGWTSGRQNAQ--NLDLNRNFPDLTSEYYRLAETRGARSDHI----PIPQHYWWGKVAPE 349
Query: 215 TKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKN 251
TKA+ ++++ + ++H ++ P+ ++K+
Sbjct: 350 TKAIMKWMQT--IPFVLSASLHGGDLVVSYPFDFSKH 384
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 33.1 bits (74), Expect = 0.42
Identities = 37/217 (17%), Positives = 86/217 (39%), Gaps = 23/217 (10%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKI---IWMDCG 106
+H ++ +R + + V + +G +++ + ++ S G + + + +
Sbjct: 187 HHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLIGN 246
Query: 107 IHAREWIAPAFCQWFVKEILQNHK-DNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTDRLW 165
IH E + + + + N I++LL ++LP +N DGY +
Sbjct: 247 IHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGAGY 306
Query: 166 RKSRSPHNNGTCFGTDLNRNF---NASWCSIGASRNCQDQTFCGTGPVSE--------PE 214
S N DLNRNF + + + +R + P+ + PE
Sbjct: 307 NGWTSGRQNAQ--NLDLNRNFPDLTSEYYRLAETRGARSDHI----PIPQHYWWGKVAPE 360
Query: 215 TKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKN 251
TKA+ ++++ + ++H ++ P+ ++K+
Sbjct: 361 TKAIMKWMQT--IPFVLSASLHGGDLVVSYPFDFSKH 395
>gi|24307911 acid sphingomyelinase-like phosphodiesterase 3A [Homo
sapiens]
Length = 453
Score = 31.6 bits (70), Expect = 1.2
Identities = 37/128 (28%), Positives = 54/128 (42%), Gaps = 33/128 (25%)
Query: 53 MGEIY-EWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIHARE 111
M E Y E + +I +KY +V+ F G TH + +S G+P +
Sbjct: 267 MREYYNEKLIDIFQKYSDVIAGQFYG---HTHRDSIMVLSDKKGSPVNSL---------- 313
Query: 112 WIAPAFCQWFVKEILQNHKDNSSIR---------KLLRNLDFYV-LPVLNIDG------- 154
++APA VK +L+ +N IR KLL L +Y+ L N+ G
Sbjct: 314 FVAPAVTP--VKSVLEKQTNNPGIRLFQYDPRDYKLLDMLQYYLNLTEANLKGESIWKLE 371
Query: 155 YIYTWTTD 162
YI T T D
Sbjct: 372 YILTQTYD 379
>gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens]
Length = 1139
Score = 30.4 bits (67), Expect = 2.7
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 25/111 (22%)
Query: 68 KEVVTQHFLGVTYETHPMYYLKISQPSGNPKKIIWMDCGIH----------AREWIAPAF 117
KE+V +F G++ + H K S+PS +P II C +H + P
Sbjct: 247 KELVNPNFKGLSEDFHA----KDSKPSSDPPCIIEKLCSLHDGLVLEAKGIKEHFWKPYI 302
Query: 118 CQWFVKEILQNHKDN-----------SSIRKLLRNLDFYVLPVLNIDGYIY 157
+ + K++L+ ++N S + + + + YVL V N+D I+
Sbjct: 303 RKLYEKKLLKGKEENLTGFLEPGNFGESFKAINKAYEEYVLSVGNLDERIF 353
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 28.9 bits (63), Expect = 7.8
Identities = 31/144 (21%), Positives = 61/144 (42%), Gaps = 12/144 (8%)
Query: 50 YHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYLKISQPSG--NPKKIIWMDCG- 106
YH E+ E + + + + + +G ++E + +++S G P + + G
Sbjct: 53 YHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPEFKYIGN 112
Query: 107 IHAREWIAPAFCQWFVKEILQNH-KDNSSIRKLLRNLDFYVLPVLNIDGYIYTWTTD--- 162
+H E + + + + + K N +I L+ + +++P LN DG+ +
Sbjct: 113 MHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKAASQPGEL 172
Query: 163 RLWRKSRSPHNNGTCFGTDLNRNF 186
+ W RS G DLNRNF
Sbjct: 173 KDWFVGRS-----NAQGIDLNRNF 191
>gi|93102361 palladin [Homo sapiens]
Length = 1106
Score = 28.9 bits (63), Expect = 7.8
Identities = 15/44 (34%), Positives = 24/44 (54%)
Query: 195 ASRNCQDQTFCGTGPVSEPETKAVASFIESKKDDILCFLTMHSY 238
ASR QD P++E +TK+++S + +K + LT SY
Sbjct: 90 ASRRPQDNRSTPVQPLAEKQTKSISSPVSKRKPAMSPLLTRPSY 133
>gi|21361659 importin 9 [Homo sapiens]
Length = 1041
Score = 28.9 bits (63), Expect = 7.8
Identities = 14/43 (32%), Positives = 25/43 (58%), Gaps = 1/43 (2%)
Query: 121 FVKEILQNHKDNSSIRKLLRNLDFYVLPVLNI-DGYIYTWTTD 162
FV +L+N K S+++K L L +Y++ + I + I WT +
Sbjct: 339 FVHALLENSKFKSTVKKALPELIYYIILYMQITEEQIKVWTAN 381
>gi|13775238 plasmalemma vesicle associated protein [Homo sapiens]
Length = 442
Score = 28.9 bits (63), Expect = 7.8
Identities = 10/19 (52%), Positives = 14/19 (73%)
Query: 36 SVSPWSLETYSYNIYHPMG 54
S+ P SL+ YN+YHP+G
Sbjct: 244 SIIPRSLDNLGYNLYHPLG 262
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,666,038
Number of Sequences: 37866
Number of extensions: 646642
Number of successful extensions: 1339
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1301
Number of HSP's gapped (non-prelim): 34
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.