Search of human proteins with 25952102

Search of human proteins with 25952102

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25952102 calcium-activated potassium channel beta 3 subunit
isoform b [Homo sapiens]
         (257 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25952102 calcium-activated potassium channel beta 3 subunit i...   537   e-153
gi|25952095 calcium-activated potassium channel beta 3 subunit i...   535   e-152
gi|25952105 calcium-activated potassium channel beta 3 subunit i...   535   e-152
gi|25952099 calcium-activated potassium channel beta 3 subunit i...   535   e-152
gi|31317295 calcium-activated potassium channel beta 2 subunit [...   185   4e-47
gi|5031823 calcium-activated potassium channel beta 2 subunit [H...   185   4e-47
gi|26051275 calcium-activated potassium channel beta 4 subunit [...   139   3e-33
gi|4758626 potassium large conductance calcium-activated channel...    94   2e-19
gi|21314682 transient receptor potential cation channel, subfami...    28   7.9  

>gi|25952102 calcium-activated potassium channel beta 3 subunit
           isoform b [Homo sapiens]
          Length = 257

 Score =  537 bits (1384), Expect = e-153
 Identities = 257/257 (100%), Positives = 257/257 (100%)

Query: 1   MTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 60
           MTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK
Sbjct: 1   MTAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILK 60

Query: 61  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 120
           PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH
Sbjct: 61  PFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLH 120

Query: 121 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 180
           YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI
Sbjct: 121 YNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILI 180

Query: 181 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 240
           KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH
Sbjct: 181 KKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQH 240

Query: 241 QFKLCIMRRSKGRAEKS 257
           QFKLCIMRRSKGRAEKS
Sbjct: 241 QFKLCIMRRSKGRAEKS 257


>gi|25952095 calcium-activated potassium channel beta 3 subunit
           isoform d [Homo sapiens]
          Length = 279

 Score =  535 bits (1379), Expect = e-152
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 2   TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 61
           TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
Sbjct: 24  TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 83

Query: 62  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 121
           FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
Sbjct: 84  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 143

Query: 122 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 181
           NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
Sbjct: 144 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 203

Query: 182 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 241
           KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
Sbjct: 204 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 263

Query: 242 FKLCIMRRSKGRAEKS 257
           FKLCIMRRSKGRAEKS
Sbjct: 264 FKLCIMRRSKGRAEKS 279


>gi|25952105 calcium-activated potassium channel beta 3 subunit
           isoform c [Homo sapiens]
          Length = 275

 Score =  535 bits (1379), Expect = e-152
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 2   TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 61
           TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
Sbjct: 20  TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 79

Query: 62  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 121
           FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
Sbjct: 80  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 139

Query: 122 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 181
           NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
Sbjct: 140 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 199

Query: 182 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 241
           KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
Sbjct: 200 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 259

Query: 242 FKLCIMRRSKGRAEKS 257
           FKLCIMRRSKGRAEKS
Sbjct: 260 FKLCIMRRSKGRAEKS 275


>gi|25952099 calcium-activated potassium channel beta 3 subunit
           isoform a [Homo sapiens]
          Length = 277

 Score =  535 bits (1379), Expect = e-152
 Identities = 256/256 (100%), Positives = 256/256 (100%)

Query: 2   TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 61
           TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP
Sbjct: 22  TAFPASGKKRETDYSDGDPLDVHKRLPSSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKP 81

Query: 62  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 121
           FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY
Sbjct: 82  FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHY 141

Query: 122 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 181
           NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK
Sbjct: 142 NEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIK 201

Query: 182 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 241
           KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ
Sbjct: 202 KYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQ 261

Query: 242 FKLCIMRRSKGRAEKS 257
           FKLCIMRRSKGRAEKS
Sbjct: 262 FKLCIMRRSKGRAEKS 277


>gi|31317295 calcium-activated potassium channel beta 2 subunit
           [Homo sapiens]
          Length = 235

 Score =  185 bits (469), Expect = 4e-47
 Identities = 93/212 (43%), Positives = 135/212 (63%), Gaps = 4/212 (1%)

Query: 17  DGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTA 75
           D D LD  K + +  AGEDRA++LG AMM  S++M+FLLG T+L+ +M S+  EES CT 
Sbjct: 27  DHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTL 86

Query: 76  IHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYT 135
           ++  I + + +C+F+CG  C    +YPCLQV+VNL+  G+K LL++ EE ++IN KC Y 
Sbjct: 87  LNASITETF-NCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYI 145

Query: 136 PKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWP 195
           PKC ++  + ++    + E F  +    FSC+  P    + VIL K Y    +FH LFWP
Sbjct: 146 PKCGKNFEESMSLVNVVMENF--RKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWP 203

Query: 196 SLTLLGGALIVGMVRLTQHLSLLCEKYSTVVR 227
           +  + GG  IV MV+LTQ+LSLLCE+   + R
Sbjct: 204 TCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 235


>gi|5031823 calcium-activated potassium channel beta 2 subunit [Homo
           sapiens]
          Length = 235

 Score =  185 bits (469), Expect = 4e-47
 Identities = 93/212 (43%), Positives = 135/212 (63%), Gaps = 4/212 (1%)

Query: 17  DGDPLDVHKRLPS-SAGEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTA 75
           D D LD  K + +  AGEDRA++LG AMM  S++M+FLLG T+L+ +M S+  EES CT 
Sbjct: 27  DHDLLDKRKTVTALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTL 86

Query: 76  IHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYT 135
           ++  I + + +C+F+CG  C    +YPCLQV+VNL+  G+K LL++ EE ++IN KC Y 
Sbjct: 87  LNASITETF-NCSFSCGPDCWKLSQYPCLQVYVNLTSSGEKLLLYHTEETIKINQKCSYI 145

Query: 136 PKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWP 195
           PKC ++  + ++    + E F  +    FSC+  P    + VIL K Y    +FH LFWP
Sbjct: 146 PKCGKNFEESMSLVNVVMENF--RKYQHFSCYSDPEGNQKSVILTKLYSSNVLFHSLFWP 203

Query: 196 SLTLLGGALIVGMVRLTQHLSLLCEKYSTVVR 227
           +  + GG  IV MV+LTQ+LSLLCE+   + R
Sbjct: 204 TCMMAGGVAIVAMVKLTQYLSLLCERIQRINR 235


>gi|26051275 calcium-activated potassium channel beta 4 subunit
           [Homo sapiens]
          Length = 210

 Score =  139 bits (349), Expect = 3e-33
 Identities = 61/189 (32%), Positives = 109/189 (57%), Gaps = 1/189 (0%)

Query: 33  EDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCG 92
           ED+++ LG  ++   V+  F+ G   L P +  +Q  E+ CT +    + +  +C FTCG
Sbjct: 14  EDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCG 73

Query: 93  VHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDI 152
             C G  +YPC+QV+VN S    +ALLH +E  +  NPKC Y P C ++    L S ++ 
Sbjct: 74  ADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNW 133

Query: 153 KEFFDHKNGT-PFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRL 211
           ++++  + G+ PF+C+++   + +DV+L + +D++ + HC  WP +T + G LIV +   
Sbjct: 134 QQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTIC 193

Query: 212 TQHLSLLCE 220
            + L++  E
Sbjct: 194 AKSLAVKAE 202


>gi|4758626 potassium large conductance calcium-activated channel,
           subfamily M, beta member 1 [Homo sapiens]
          Length = 191

 Score = 93.6 bits (231), Expect = 2e-19
 Identities = 59/189 (31%), Positives = 94/189 (49%), Gaps = 15/189 (7%)

Query: 32  GEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTC 91
           GE RA+ LG  M+  +V+ +++L TT+L  +  S+  +ES C  I T+I D         
Sbjct: 12  GETRALCLGVTMVVCAVITYYILVTTVLPLYQKSVWTQESKCHLIETNIRDQ-------- 63

Query: 92  GVHCHGQG--KYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSA 149
                G+   +YPCL  +VN+S  G+ A+L++ E+    N +C Y P    +        
Sbjct: 64  -EELKGKKVPQYPCL--WVNVSAAGRWAVLYHTEDTRDQNQQCSYIPGSVDNYQTARADV 120

Query: 150 LDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMV 209
             ++  F  +    F CF +P      V+  + Y   A+   LFWP+  L GG LI+ MV
Sbjct: 121 EKVRAKFQEQQ--VFYCFSAPRGNETSVLFQRLYGPQALLFSLFWPTFLLTGGLLIIAMV 178

Query: 210 RLTQHLSLL 218
           +  Q+LS+L
Sbjct: 179 KSNQYLSIL 187


>gi|21314682 transient receptor potential cation channel, subfamily
           V, member 6 [Homo sapiens]
          Length = 725

 Score = 28.1 bits (61), Expect = 7.9
 Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 3/44 (6%)

Query: 26  RLPSSAGEDRAVMLGFAM-MGFSVLMFFLLGTTILKPFMLSIQR 68
           RL S++GE   V + FA+ +G+  +M+F  G  +L PF + IQ+
Sbjct: 443 RLISASGE--VVPMSFALVLGWCNVMYFARGFQMLGPFTIMIQK 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,166,773
Number of Sequences: 37866
Number of extensions: 439453
Number of successful extensions: 1114
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1099
Number of HSP's gapped (non-prelim): 9
length of query: 257
length of database: 18,247,518
effective HSP length: 100
effective length of query: 157
effective length of database: 14,460,918
effective search space: 2270364126
effective search space used: 2270364126
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.