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Search of human proteins with 24041029
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24041029 nitric oxide synthase 2A [Homo sapiens]
(1153 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24041029 nitric oxide synthase 2A [Homo sapiens] 2377 0.0
gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens] 1232 0.0
gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens] 1158 0.0
gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens] 637 0.0
gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens] 637 0.0
gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens] 636 0.0
gi|127139033 cytochrome P450 reductase [Homo sapiens] 258 3e-68
gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [... 191 4e-48
gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens] 188 3e-47
gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens] 188 3e-47
gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a... 187 6e-47
gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c... 183 7e-46
gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d... 176 1e-43
gi|50726981 radical S-adenosyl methionine and flavodoxin domains... 37 0.11
gi|18496983 CAP-GLY domain containing linker protein 3 [Homo sap... 33 1.2
gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens] 32 4.5
gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1 ... 32 4.5
gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapi... 32 4.5
gi|29570798 phosphoribosyl pyrophosphate amidotransferase propro... 31 7.8
gi|68348723 zinc finger protein 711 [Homo sapiens] 31 7.8
>gi|24041029 nitric oxide synthase 2A [Homo sapiens]
Length = 1153
Score = 2377 bits (6160), Expect = 0.0
Identities = 1153/1153 (100%), Positives = 1153/1153 (100%)
Query: 1 MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLSKQQNESPQPL 60
MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLSKQQNESPQPL
Sbjct: 1 MACPWKFLFKTKFHQYAMNGEKDINNNVEKAPCATSSPVTQDDLQYHNLSKQQNESPQPL 60
Query: 61 VETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIM 120
VETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIM
Sbjct: 61 VETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIM 120
Query: 121 TPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ 180
TPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ
Sbjct: 121 TPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ 180
Query: 181 LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNI 240
LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNI
Sbjct: 181 LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNI 240
Query: 241 RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG 300
RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG
Sbjct: 241 RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYG 300
Query: 301 RFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVG 360
RFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVG
Sbjct: 301 RFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVG 360
Query: 361 GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINI 420
GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINI
Sbjct: 361 GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINI 420
Query: 421 AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEM 480
AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEM
Sbjct: 421 AVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEM 480
Query: 481 LNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVT 540
LNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVT
Sbjct: 481 LNYVLSPFYYYQVEAWKTHVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVT 540
Query: 541 ILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPG 600
ILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPG
Sbjct: 541 ILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPG 600
Query: 601 NGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGD 660
NGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGD
Sbjct: 601 NGEKLKKSLFMLKELNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGD 660
Query: 661 ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDL 720
ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDL
Sbjct: 661 ELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLVQDSQPLDL 720
Query: 721 SKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQ 780
SKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQ
Sbjct: 721 SKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQ 780
Query: 781 PALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQ 840
PALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQ
Sbjct: 781 PALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLPPCSLSQALTYFLDITTPPTQ 840
Query: 841 LLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL 900
LLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL
Sbjct: 841 LLLQKLAQVATEEPERQRLEALCQPSEYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQL 900
Query: 901 PILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCF 960
PILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCF
Sbjct: 901 PILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCF 960
Query: 961 VRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPD 1020
VRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPD
Sbjct: 961 VRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPD 1020
Query: 1021 EDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLY 1080
EDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLY
Sbjct: 1021 EDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLY 1080
Query: 1081 VCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDR 1140
VCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDR
Sbjct: 1081 VCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDR 1140
Query: 1141 VAVQPSSLEMSAL 1153
VAVQPSSLEMSAL
Sbjct: 1141 VAVQPSSLEMSAL 1153
>gi|10835173 nitric oxide synthase 1, neuronal [Homo sapiens]
Length = 1434
Score = 1232 bits (3187), Expect = 0.0
Identities = 615/1133 (54%), Positives = 779/1133 (68%), Gaps = 58/1133 (5%)
Query: 49 LSKQQNESPQPLVETGKKSPESLVKLDATPLSSPRHVRIKNWGSGMTFQDTLHHKAKGIL 108
L+ +E QP +GK+SP + +P PR +++KNW + + DTLH K+
Sbjct: 275 LNNPYSEKEQPPT-SGKQSPTK----NGSPSKCPRFLKVKNWETEVVLTDTLHLKSTLET 329
Query: 109 TCRSKSCLGSIMTPKSLTRGPRDKPTPPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEA 168
C C+GSIM P R P D T +L P A EF++QYY S K + H+ R+E
Sbjct: 330 GCTEYICMGSIMHPSQHARRPEDVRTK-GQLFPLAKEFIDQYYSSIKRFGSKAHMERLEE 388
Query: 169 VTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAREMFEHIC 228
V KEI+TT TYQL ELI+ K AWRNA RC+GRIQWS LQVFDAR C+TA MF +IC
Sbjct: 389 VNKEIDTTSTYQLKDTELIYGAKHAWRNASRCVGRIQWSKLQVFDARDCTTAHGMFNYIC 448
Query: 229 RHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGSIRGDPANVEFTQ 288
HV+Y+TN GN+RSAIT+FPQR+DGKHDFRVWN+QLIRYAGY+ PDGS GDPANV+FT+
Sbjct: 449 NHVKYATNKGNLRSAITIFPQRTDGKHDFRVWNSQLIRYAGYKQPDGSTLGDPANVQFTE 508
Query: 289 LCIDLGWKPKYGRFDVVPLVLQANGRDPELFEIPPDLVLEVAMEHPKYEWFRELELKWYA 348
+CI GWKP GRFDV+PL+LQANG DPELF+IPP+LVLEV + HPK+EWF++L LKWY
Sbjct: 509 ICIQQGWKPPRGRFDVLPLLLQANGNDPELFQIPPELVLEVPIRHPKFEWFKDLGLKWYG 568
Query: 349 LPAVANMLLEVGGLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKLAS 408
LPAV+NMLLE+GGLEF CPF+GWYMGTEIGVRD+CD RYNILEEV ++M L+ K +S
Sbjct: 569 LPAVSNMLLEIGGLEFSACPFSGWYMGTEIGVRDYCDNSRYNILEEVAKKMNLDMRKTSS 628
Query: 409 LWKDQAVVEINIAVLHSFQKQNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPM 468
LWKDQA+VEINIAVL+SFQ VTI+DHHSA ESF+K+M+NEYR RGGCPADW+W+VPPM
Sbjct: 629 LWKDQALVEINIAVLYSFQSDKVTIVDHHSATESFIKHMENEYRCRGGCPADWVWIVPPM 688
Query: 469 SGSITPVFHQEMLNYVLSPFYYYQVEAWKTHVWQDEKRRP-KRREIPLKVLVKAVLFACM 527
SGSITPVFHQEMLNY L+P + YQ + W THVW+ P KRR I K L +AV F+
Sbjct: 689 SGSITPVFHQEMLNYRLTPSFEYQPDPWNTHVWKGTNGTPTKRRAIGFKKLAEAVKFSAK 748
Query: 528 LMRKTMASRVRVTILFATETGKSEALAWDLGALFSCAFNPKVVCMDKYRLSCLEEERLLL 587
LM + MA RV+ TIL+ATETGKS+A A L +F AF+ KV+ M++Y + LE E L+L
Sbjct: 749 LMGQAMAKRVKATILYATETGKSQAYAKTLCEIFKHAFDAKVMSMEEYDIVHLEHETLVL 808
Query: 588 VVTSTFGNGDCPGNGEKLKKSLFMLKELNN------------------------------ 617
VVTSTFGNGD P NGEK +L ++ N+
Sbjct: 809 VVTSTFGNGDPPENGEKFGCALMEMRHPNSVQEERKSYKVRFNSVSSYSDSQKSSGDGPD 868
Query: 618 ------------KFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQ 665
R++VFGLGS YP FCAF H +D L LG ++ M EGDEL GQ
Sbjct: 869 LRDNFESAGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELCGQ 928
Query: 666 EDAFRSWAVQTFKAACETFDVRGKQHIQIP--KLYTSNVTWDPHHYRLVQDSQPLDLSKA 723
E+AFR+WA + FKAAC+ F V +I+ L +++ +W + +RL ++ +L++
Sbjct: 929 EEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTFVAEAPELTQG 988
Query: 724 LSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQPAL 783
LS++H K V RL SRQNLQSP SSR+TI V L Q L Y PG+HLGV PGN L
Sbjct: 989 LSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGSQELQYQPGDHLGVFPGNHEDL 1048
Query: 784 VQGILERVVDGPTPHQTVRLEALDESG------SYWVSDKRLPPCSLSQALTYFLDITTP 837
V ++ER+ D P +Q V++E L+E S W + RLPPC++ QA Y+LDITTP
Sbjct: 1049 VNALIERLEDAPPVNQMVKVELLEERNTALGVISNWTDELRLPPCTIFQAFKYYLDITTP 1108
Query: 838 PTQLLLQKLAQVATEEPERQRLEALCQP-SEYSKWKFTNSPTFLEVLEEFPSLRVSAGFL 896
PT L LQ+ A +AT E E+QRL L + EY +WK+ +PT +EVLEEFPS+++ A L
Sbjct: 1109 PTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPATLL 1168
Query: 897 LSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDP 956
L+QL +L+PR+YSISSS D P E+HLTVA+V+Y TRDG+GP+HHGVCS+WLN ++ +
Sbjct: 1169 LTQLSLLQPRYYSISSSPDMYPDEVHLTVAIVSYRTRDGEGPIHHGVCSSWLNRIQADEL 1228
Query: 957 VPCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGC 1016
VPCFVR A FHLP +P PCIL+GPGTGIAPFRSFWQQR D QHKG+ M LVFGC
Sbjct: 1229 VPCFVRGAPSFHLPRNPQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGC 1288
Query: 1017 RRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEP 1076
R+ DHIY+EE L+ KGV ++TAYSR P KPK YVQDIL++QLA V R L ++
Sbjct: 1289 RQSKIDHIYREETLQAKNKGVFRELYTAYSREPDKPKKYVQDILQEQLAESVYRALKEQG 1348
Query: 1077 GHLYVCGDVRMARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIFG 1129
GH+YVCGDV MA DV +++++ + KL+ E + +++ RYHEDIFG
Sbjct: 1349 GHIYVCGDVTMAADVLKAIQRIMTQQGKLSAEDAGVFISRMRDDNRYHEDIFG 1401
>gi|40254422 nitric oxide synthase 3 isoform 1 [Homo sapiens]
Length = 1203
Score = 1158 bits (2996), Expect = 0.0
Identities = 578/1123 (51%), Positives = 744/1123 (66%), Gaps = 54/1123 (4%)
Query: 78 PLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPD 137
P P+ R+KNW G DTL +A+ C + CLGS++ P+ L P P P+
Sbjct: 62 PPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
Query: 138 ELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNA 197
+LL QA +F+NQYY S K + + H R++ V E+ TGTYQL EL+F KQAWRNA
Sbjct: 122 QLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA 181
Query: 198 PRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDF 257
PRC+GRIQW LQVFDAR C +A+EMF +IC H++Y+TN GN+RSAITVFPQR G+ DF
Sbjct: 182 PRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF 241
Query: 258 RVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPE 317
R+WN+QL+RYAGY+ DGS+RGDPANVE T+LCI GW P GRFDV+PL+LQA PE
Sbjct: 242 RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPE 301
Query: 318 LFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTE 377
LF +PP+LVLEV +EHP EWF L L+WYALPAV+NMLLE+GGLEFP PF+GWYM TE
Sbjct: 302 LFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE 361
Query: 378 IGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHH 437
IG R+ CD RYNILE+V M L+T +SLWKD+A VEIN+AVLHS+Q VTI+DHH
Sbjct: 362 IGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH 421
Query: 438 SAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWK 497
+A SFMK+++NE ++RGGCPADW W+VPP+SGS+TPVFHQEM+NY LSP + YQ + WK
Sbjct: 422 AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK 481
Query: 498 THVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDL 557
K R+ K + AV + LM MA RV+ TIL+ +ETG++++ A L
Sbjct: 482 GSA---AKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQL 538
Query: 558 GALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKLKKSLFML----- 612
G LF AF+P+V+CMD+Y + LE E L+LVVTSTFGNGD P NGE +L +
Sbjct: 539 GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYN 598
Query: 613 --------------------------------KELNN--------KFRYAVFGLGSSMYP 632
KE +N R+ VFGLGS YP
Sbjct: 599 SSPRPEQHKSYKIRFNSISCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP 658
Query: 633 RFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHI 692
FCAFA +D +L LG +L +G+GDEL GQE+AFR WA F+AACETF V
Sbjct: 659 HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQAACETFCVGEDAKA 718
Query: 693 QIPKLYTSNVTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRAT 752
+++ +W YRL ++ L L L +H + +F ++S +NLQS S+RAT
Sbjct: 719 AARDIFSPKRSWKRQRYRLSAQAEGLQLLPGLIHVHRRKMFQATIRSVENLQSSKSTRAT 778
Query: 753 ILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESG-- 810
ILV L +GL Y PG+H+GVCP N+P LV+ +L RV D P P + V +E L++
Sbjct: 779 ILVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPAPTEPVAVEQLEKGSPG 838
Query: 811 ---SYWVSDKRLPPCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQ-PS 866
WV D RLPPC+L QALT+FLDIT+PP+ LL+ L+ +A E E+Q LEAL Q P
Sbjct: 839 GPPPGWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPREQQELEALSQDPR 898
Query: 867 EYSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVA 926
Y +WK+ PT LEVLE+FPS+ + A LL+QLP+L+PR+YS+SS+ P EIHLTVA
Sbjct: 899 RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVA 958
Query: 927 VVTYHTRDGQGPLHHGVCSTWLNSLKPQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGI 986
V+ Y T+DG GPLH+GVCSTWL+ LKP DPVPCF+R A F LP DPS PCIL+GPGTGI
Sbjct: 959 VLAYRTQDGLGPLHYGVCSTWLSQLKPGDPVPCFIRGAPSFRLPPDPSLPCILVGPGTGI 1018
Query: 987 APFRSFWQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYS 1046
APFR FWQ+RLHD + KG++ MTLVFGCR DH+Y++E+ Q+GV V TA+S
Sbjct: 1019 APFRGFWQERLHDIESKGLQPTPMTLVFGCRCSQLDHLYRDEVQNAQQRGVFGRVLTAFS 1078
Query: 1047 RLPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVRMARDVAHTLKQLVAAKLKLN 1106
R P PK YVQDILR +LA+EV RVL E GH++VCGDV MA +V T+++++A + +
Sbjct: 1079 REPDNPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATNVLQTVQRILATEGDME 1138
Query: 1107 EEQVEDYFFQLKSQKRYHEDIFGAVFPYEAKKDRVAVQPSSLE 1149
++ D L+ Q+RYHEDIFG + R+ Q SL+
Sbjct: 1139 LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQ 1181
>gi|231571356 nitric oxide synthase 3 isoform 4 [Homo sapiens]
Length = 629
Score = 637 bits (1642), Expect = 0.0
Identities = 302/528 (57%), Positives = 380/528 (71%), Gaps = 3/528 (0%)
Query: 78 PLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPD 137
P P+ R+KNW G DTL +A+ C + CLGS++ P+ L P P P+
Sbjct: 62 PPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
Query: 138 ELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNA 197
+LL QA +F+NQYY S K + + H R++ V E+ TGTYQL EL+F KQAWRNA
Sbjct: 122 QLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA 181
Query: 198 PRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDF 257
PRC+GRIQW LQVFDAR C +A+EMF +IC H++Y+TN GN+RSAITVFPQR G+ DF
Sbjct: 182 PRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF 241
Query: 258 RVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPE 317
R+WN+QL+RYAGY+ DGS+RGDPANVE T+LCI GW P GRFDV+PL+LQA PE
Sbjct: 242 RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPE 301
Query: 318 LFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTE 377
LF +PP+LVLEV +EHP EWF L L+WYALPAV+NMLLE+GGLEFP PF+GWYM TE
Sbjct: 302 LFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE 361
Query: 378 IGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHH 437
IG R+ CD RYNILE+V M L+T +SLWKD+A VEIN+AVLHS+Q VTI+DHH
Sbjct: 362 IGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH 421
Query: 438 SAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWK 497
+A SFMK+++NE ++RGGCPADW W+VPP+SGS+TPVFHQEM+NY LSP + YQ + WK
Sbjct: 422 AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK 481
Query: 498 THVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDL 557
K R+ K + AV + LM MA RV+ TIL+ +ETG++++ A L
Sbjct: 482 GSA---AKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQL 538
Query: 558 GALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKL 605
G LF AF+P+V+CMD+Y + LE E L+LVVTSTFGNGD P NGE L
Sbjct: 539 GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGEGL 586
>gi|231571329 nitric oxide synthase 3 isoform 3 [Homo sapiens]
Length = 614
Score = 637 bits (1642), Expect = 0.0
Identities = 301/527 (57%), Positives = 380/527 (72%), Gaps = 3/527 (0%)
Query: 78 PLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPD 137
P P+ R+KNW G DTL +A+ C + CLGS++ P+ L P P P+
Sbjct: 62 PPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
Query: 138 ELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNA 197
+LL QA +F+NQYY S K + + H R++ V E+ TGTYQL EL+F KQAWRNA
Sbjct: 122 QLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA 181
Query: 198 PRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDF 257
PRC+GRIQW LQVFDAR C +A+EMF +IC H++Y+TN GN+RSAITVFPQR G+ DF
Sbjct: 182 PRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF 241
Query: 258 RVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPE 317
R+WN+QL+RYAGY+ DGS+RGDPANVE T+LCI GW P GRFDV+PL+LQA PE
Sbjct: 242 RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPE 301
Query: 318 LFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTE 377
LF +PP+LVLEV +EHP EWF L L+WYALPAV+NMLLE+GGLEFP PF+GWYM TE
Sbjct: 302 LFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE 361
Query: 378 IGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHH 437
IG R+ CD RYNILE+V M L+T +SLWKD+A VEIN+AVLHS+Q VTI+DHH
Sbjct: 362 IGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH 421
Query: 438 SAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWK 497
+A SFMK+++NE ++RGGCPADW W+VPP+SGS+TPVFHQEM+NY LSP + YQ + WK
Sbjct: 422 AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK 481
Query: 498 THVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDL 557
K R+ K + AV + LM MA RV+ TIL+ +ETG++++ A L
Sbjct: 482 GSA---AKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQL 538
Query: 558 GALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEK 604
G LF AF+P+V+CMD+Y + LE E L+LVVTSTFGNGD P NGE+
Sbjct: 539 GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGER 585
>gi|231571314 nitric oxide synthase 3 isoform 2 [Homo sapiens]
Length = 596
Score = 636 bits (1641), Expect = 0.0
Identities = 301/528 (57%), Positives = 380/528 (71%), Gaps = 3/528 (0%)
Query: 78 PLSSPRHVRIKNWGSGMTFQDTLHHKAKGILTCRSKSCLGSIMTPKSLTRGPRDKPTPPD 137
P P+ R+KNW G DTL +A+ C + CLGS++ P+ L P P P+
Sbjct: 62 PPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAPE 121
Query: 138 ELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQLTGDELIFATKQAWRNA 197
+LL QA +F+NQYY S K + + H R++ V E+ TGTYQL EL+F KQAWRNA
Sbjct: 122 QLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWRNA 181
Query: 198 PRCIGRIQWSNLQVFDARSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDF 257
PRC+GRIQW LQVFDAR C +A+EMF +IC H++Y+TN GN+RSAITVFPQR G+ DF
Sbjct: 182 PRCVGRIQWGKLQVFDARDCRSAQEMFTYICNHIKYATNRGNLRSAITVFPQRCPGRGDF 241
Query: 258 RVWNAQLIRYAGYQMPDGSIRGDPANVEFTQLCIDLGWKPKYGRFDVVPLVLQANGRDPE 317
R+WN+QL+RYAGY+ DGS+RGDPANVE T+LCI GW P GRFDV+PL+LQA PE
Sbjct: 242 RIWNSQLVRYAGYRQQDGSVRGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDDPPE 301
Query: 318 LFEIPPDLVLEVAMEHPKYEWFRELELKWYALPAVANMLLEVGGLEFPGCPFNGWYMGTE 377
LF +PP+LVLEV +EHP EWF L L+WYALPAV+NMLLE+GGLEFP PF+GWYM TE
Sbjct: 302 LFLLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMSTE 361
Query: 378 IGVRDFCDVQRYNILEEVGRRMGLETHKLASLWKDQAVVEINIAVLHSFQKQNVTIMDHH 437
IG R+ CD RYNILE+V M L+T +SLWKD+A VEIN+AVLHS+Q VTI+DHH
Sbjct: 362 IGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINVAVLHSYQLAKVTIVDHH 421
Query: 438 SAAESFMKYMQNEYRSRGGCPADWIWLVPPMSGSITPVFHQEMLNYVLSPFYYYQVEAWK 497
+A SFMK+++NE ++RGGCPADW W+VPP+SGS+TPVFHQEM+NY LSP + YQ + WK
Sbjct: 422 AATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFRYQPDPWK 481
Query: 498 THVWQDEKRRPKRREIPLKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDL 557
K R+ K + AV + LM MA RV+ TIL+ +ETG++++ A L
Sbjct: 482 GSA---AKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQL 538
Query: 558 GALFSCAFNPKVVCMDKYRLSCLEEERLLLVVTSTFGNGDCPGNGEKL 605
G LF AF+P+V+CMD+Y + LE E L+LVVTSTFGNGD P NGE +
Sbjct: 539 GRLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESV 586
>gi|127139033 cytochrome P450 reductase [Homo sapiens]
Length = 680
Score = 258 bits (658), Expect = 3e-68
Identities = 207/651 (31%), Positives = 312/651 (47%), Gaps = 48/651 (7%)
Query: 507 RPKRREIP----LKVLVKAVLFACMLMRKTMASRVRVTILFATETGKSEALAWDLG---- 558
R K+ E+P ++ L +V + + + R + + + ++TG +E A L
Sbjct: 48 RKKKEEVPEFTKIQTLTSSVRESSFVEKMKKTGR-NIIVFYGSQTGTAEEFANRLSKDAH 106
Query: 559 --ALFSCAFNPKVVCMDKYRLSCLEEERLLLVV--TSTFGNGDCPGNGEKLKKSLFMLKE 614
+ + +P+ D LS L E LVV +T+G GD N + L
Sbjct: 107 RYGMRGMSADPEEY--DLADLSSLPEIDNALVVFCMATYGEGDPTDNAQDFYDWLQETDV 164
Query: 615 LNNKFRYAVFGLGSSMYPRFCAFAHDIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAV 674
+ ++AVFGLG+ Y F A +D++L LGA ++ +G GD+ E+ F +W
Sbjct: 165 DLSGVKFAVFGLGNKTYEHFNAMGKYVDKRLEQLGAQRIFELGLGDDDGNLEEDFITWRE 224
Query: 675 QTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHHYRLV--QDSQPLDLSKALSSMHAKNV 732
Q + A CE F V + Y V D ++ + + AKN
Sbjct: 225 QFWPAVCEHFGVEATGEESSIRQYELVVHTDIDAAKVYMGEMGRLKSYENQKPPFDAKNP 284
Query: 733 FTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYLPGEHLGVCPGNQPALVQGILERVV 792
F + + + L T R + +EL D + + Y G+H+ V P N ALV + + +
Sbjct: 285 FLAAVTTNRKLNQGT-ERHLMHLELDISDSK-IRYESGDHVAVYPANDSALVNQLGK--I 340
Query: 793 DGPTPHQTVRLEALDESGSYWVSDKRLP---PCSLSQALTYFLDITTPPTQLLLQKLAQV 849
G + L LDE S+K+ P P S ALTY+LDIT PP +L +LAQ
Sbjct: 341 LGADLDVVMSLNNLDEE-----SNKKHPFPCPTSYRTALTYYLDITNPPRTNVLYELAQY 395
Query: 850 ATEEPERQRLEALCQPSE-----YSKWKFTNSPTFLEVLEEFPSLRVSAGFLLSQLPILK 904
A+E E++ L + S Y W L +L++ PSLR L LP L+
Sbjct: 396 ASEPSEQELLRKMASSSGEGKELYLSWVVEARRHILAILQDCPSLRPPIDHLCELLPRLQ 455
Query: 905 PRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHGVCSTWLNSLKPQDP------VP 958
R+YSI+SS P +H+ VV Y T+ G+ ++ GV + WL + +P VP
Sbjct: 456 ARYYSIASSSKVHPNSVHICAVVVEYETKAGR--INKGVATNWLRAKEPAGENGGRALVP 513
Query: 959 CFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTLVFGCRR 1018
FVR S F LP + P I++GPGTG+APF F Q+R Q +G G L +GCRR
Sbjct: 514 MFVRK-SQFRLPFKATTPVIMVGPGTGVAPFIGFIQERAWLRQ-QGKEVGETLLYYGCRR 571
Query: 1019 PDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDILRQQLASEVLRVLHKEPGH 1078
DED++Y+EE+ + + G L ++ A+SR KVYVQ +L+Q E L L + H
Sbjct: 572 SDEDYLYREELAQFHRDGALTQLNVAFSR-EQSHKVYVQHLLKQD--REHLWKLIEGGAH 628
Query: 1079 LYVCGDVR-MARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIF 1128
+YVCGD R MARDV +T +VA + Q DY +L ++ RY D++
Sbjct: 629 IYVCGDARNMARDVQNTFYDIVAELGAMEHAQAVDYIKKLMTKGRYSLDVW 679
>gi|7657393 NADPH dependent diflavin oxidoreductase 1 isoform b [Homo
sapiens]
Length = 597
Score = 191 bits (484), Expect = 4e-48
Identities = 175/615 (28%), Positives = 292/615 (47%), Gaps = 51/615 (8%)
Query: 538 RVTILFATETGKSEALAWDLGA-----LFSCAFNPKVVCMDKYRLSCLEEERLLLVVTST 592
++ +LF ++TG ++ ++ LG C +V +D Y + L E L++ V +T
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGC----RVQALDSYPVVNLINEPLVIFVCAT 60
Query: 593 FGNGDCPGNGEKLKKSLFMLKELNN----KFRYAVFGLGSSMYPRFCAFAHDIDQKLSHL 648
G GD P N + + +F K L + + +AV GLG S Y +F A + ++L L
Sbjct: 61 TGQGDPPDNMKNFWRFIFR-KNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQL 119
Query: 649 GASQLTPMGEGDELS--GQEDAFRSWAVQTFKAACETFD-----VRGKQHIQIPKLYTSN 701
G S L P+ GD+ G + A W + + + +P +T
Sbjct: 120 GGSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFT-- 177
Query: 702 VTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCED 761
+ + + Q + + F + S Q + P+ + L+E
Sbjct: 178 LLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDIL- 236
Query: 762 GQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLP- 820
G G+++ G+ + + P N A VQ + V G P Q L+ + S S RLP
Sbjct: 237 GSGISFAAGDVVLIQPSNSAAHVQRFCQ--VLGLDPDQLFMLQPREPDVS---SPTRLPQ 291
Query: 821 PCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRL-EALCQPSEYSKWKFTNSP-- 877
PCS+ ++++LDI + P + + LA ++ E ER++L E + +++ N P
Sbjct: 292 PCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRR 351
Query: 878 TFLEVLEEFP--SLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDG 935
T LEVL +FP + + +LL +P+++PR +SI+SS P+ + + VAVV + TR
Sbjct: 352 TILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLK 411
Query: 936 QGPLHHGVCSTWLNSLKP-QDPV--PCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSF 992
+ G+CS+WL SL P Q PV P +VR S PE P P I++GPGTG+APFR+
Sbjct: 412 EP--RRGLCSSWLASLDPGQGPVRVPLWVRPGS-LAFPETPDTPVIMVGPGTGVAPFRAA 468
Query: 993 WQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKP 1052
Q+R+ Q L FGCR D+D ++ E E+ ++ L + A+SR +
Sbjct: 469 IQERVAQGQTGNF------LFFGCRWRDQDFYWEAEWQELEKRDCLTLI-PAFSR-EQEQ 520
Query: 1053 KVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVR-MARDVAHTLKQLVAAKLKLNEEQVE 1111
KVYVQ LR +L S V +L ++ + Y+ G+ + M DV+ L + + L
Sbjct: 521 KVYVQHRLR-ELGSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAA 579
Query: 1112 DYFFQLKSQKRYHED 1126
Y +L+ +R+ +
Sbjct: 580 AYLARLQQTRRFQTE 594
>gi|169790958 methionine synthase reductase isoform 1 [Homo sapiens]
Length = 698
Score = 188 bits (477), Expect = 3e-47
Identities = 138/459 (30%), Positives = 221/459 (48%), Gaps = 33/459 (7%)
Query: 701 NVTWDPHHYRLVQDSQPLDLSKA-LSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSC 759
N+ P Y V + L ++ +S A VF + + L + + + T+LVEL
Sbjct: 241 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI 300
Query: 760 EDGQGLNYLPGEHLGVCPGNQPALVQGILERV-VDGPTPHQTVRLEALDESGSYWVSDKR 818
+ +Y PG+ V N + VQ +L+R+ ++ H + D +
Sbjct: 301 SNTD-FSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQH 359
Query: 819 LPP-CSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQP---SEYSKWKFT 874
+P CSL T+ L+I P + L+ L ++ E++RL+ LC ++YS++
Sbjct: 360 IPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRD 419
Query: 875 NSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRD 934
L++L FPS + LL LP L+PR YS +SS P ++H +V + +
Sbjct: 420 ACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTA 479
Query: 935 GQGPLHHGVCSTWL-----NSLKPQ-------------DPVPCFVRNASGFHLPEDPSHP 976
L GVC+ WL + L+P + R + FHLP+DPS P
Sbjct: 480 TTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIP 539
Query: 977 CILIGPGTGIAPFRSFWQQRLH-DSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQK 1035
I++GPGTGIAPF F Q R QH G M L FGCR D D+++++E+ +
Sbjct: 540 IIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKH 599
Query: 1036 GVLHAVHTAYSR-----LPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVR-MAR 1089
G+L + ++SR P YVQD + Q +V R+L +E GH+YVCGD + MA+
Sbjct: 600 GILTHLKVSFSRDAPVGEEEAPAKYVQDNI-QLHGQQVARILLQENGHIYVCGDAKNMAK 658
Query: 1090 DVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIF 1128
DV L Q+++ ++ + + + LK +KRY +DI+
Sbjct: 659 DVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIW 697
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/169 (30%), Positives = 76/169 (44%), Gaps = 22/169 (13%)
Query: 538 RVTILFATETGKSEALAWDL-GALFSCAFNPKVVCM---DKYRLSCLEEERLLLVVTSTF 593
R +L+AT+ G+++A+A ++ F+ + C+ DKY L E L+VV ST
Sbjct: 3 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKT--ETAPLVVVVSTT 60
Query: 594 GNGDCPGNGEKLKKSLFMLKELNNK---------FRYAVFGLGSSMYPRFCAFAHDIDQK 644
G GD P K +KE+ N+ RY + GLG S Y FC ID++
Sbjct: 61 GTGDPPDTARKF------VKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKR 114
Query: 645 LSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETF-DVRGKQHI 692
L LGA G D+ G E W + A + F RG++ I
Sbjct: 115 LQELGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEI 163
>gi|169790956 methionine synthase reductase isoform 2 [Homo sapiens]
Length = 725
Score = 188 bits (477), Expect = 3e-47
Identities = 138/459 (30%), Positives = 221/459 (48%), Gaps = 33/459 (7%)
Query: 701 NVTWDPHHYRLVQDSQPLDLSKA-LSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSC 759
N+ P Y V + L ++ +S A VF + + L + + + T+LVEL
Sbjct: 268 NIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDI 327
Query: 760 EDGQGLNYLPGEHLGVCPGNQPALVQGILERV-VDGPTPHQTVRLEALDESGSYWVSDKR 818
+ +Y PG+ V N + VQ +L+R+ ++ H + D +
Sbjct: 328 SNTD-FSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQH 386
Query: 819 LPP-CSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRLEALCQP---SEYSKWKFT 874
+P CSL T+ L+I P + L+ L ++ E++RL+ LC ++YS++
Sbjct: 387 IPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRD 446
Query: 875 NSPTFLEVLEEFPSLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRD 934
L++L FPS + LL LP L+PR YS +SS P ++H +V + +
Sbjct: 447 ACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTA 506
Query: 935 GQGPLHHGVCSTWL-----NSLKPQ-------------DPVPCFVRNASGFHLPEDPSHP 976
L GVC+ WL + L+P + R + FHLP+DPS P
Sbjct: 507 TTEVLRKGVCTGWLALLVASVLQPNIHASHEDSGKALAPKISISPRTTNSFHLPDDPSIP 566
Query: 977 CILIGPGTGIAPFRSFWQQRLH-DSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQK 1035
I++GPGTGIAPF F Q R QH G M L FGCR D D+++++E+ +
Sbjct: 567 IIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKH 626
Query: 1036 GVLHAVHTAYSR-----LPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVR-MAR 1089
G+L + ++SR P YVQD + Q +V R+L +E GH+YVCGD + MA+
Sbjct: 627 GILTHLKVSFSRDAPVGEEEAPAKYVQDNI-QLHGQQVARILLQENGHIYVCGDAKNMAK 685
Query: 1090 DVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHEDIF 1128
DV L Q+++ ++ + + + LK +KRY +DI+
Sbjct: 686 DVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIW 724
Score = 62.8 bits (151), Expect = 2e-09
Identities = 52/169 (30%), Positives = 76/169 (44%), Gaps = 22/169 (13%)
Query: 538 RVTILFATETGKSEALAWDL-GALFSCAFNPKVVCM---DKYRLSCLEEERLLLVVTSTF 593
R +L+AT+ G+++A+A ++ F+ + C+ DKY L E L+VV ST
Sbjct: 30 RFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKT--ETAPLVVVVSTT 87
Query: 594 GNGDCPGNGEKLKKSLFMLKELNNK---------FRYAVFGLGSSMYPRFCAFAHDIDQK 644
G GD P K +KE+ N+ RY + GLG S Y FC ID++
Sbjct: 88 GTGDPPDTARKF------VKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKR 141
Query: 645 LSHLGASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETF-DVRGKQHI 692
L LGA G D+ G E W + A + F RG++ I
Sbjct: 142 LQELGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEI 190
>gi|221316705 NADPH dependent diflavin oxidoreductase 1 isoform a
[Homo sapiens]
Length = 606
Score = 187 bits (474), Expect = 6e-47
Identities = 175/623 (28%), Positives = 292/623 (46%), Gaps = 58/623 (9%)
Query: 538 RVTILFATETGKSEALAWDLGA-----LFSCAFNPKVVCMDKYRLSCLEEERLLLVVTST 592
++ +LF ++TG ++ ++ LG C +V +D Y + L E L++ V +T
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGC----RVQALDSYPVVNLINEPLVIFVCAT 60
Query: 593 FGNGDCPGNGEKLKKSLFMLKELNN----KFRYAVFGLGSSMYPRFCAFAHDIDQKLSHL 648
G GD P N + + +F K L + + +AV GLG S Y +F A + ++L L
Sbjct: 61 TGQGDPPDNMKNFWRFIFR-KNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQL 119
Query: 649 GASQLTPMGEGDELS--GQEDAFRSWAVQTFKAACETFD-----VRGKQHIQIPKLYTSN 701
G S L P+ GD+ G + A W + + + +P +T
Sbjct: 120 GGSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFT-- 177
Query: 702 VTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCED 761
+ + + Q + + F + S Q + P+ + L+E
Sbjct: 178 LLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDIL- 236
Query: 762 GQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLP- 820
G G+++ G+ + + P N A VQ + V G P Q L+ + S S RLP
Sbjct: 237 GSGISFAAGDVVLIQPSNSAAHVQRFCQ--VLGLDPDQLFMLQPREPDVS---SPTRLPQ 291
Query: 821 PCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRL-EALCQPSEYSKWKFTNSP-- 877
PCS+ ++++LDI + P + + LA ++ E ER++L E + +++ N P
Sbjct: 292 PCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRR 351
Query: 878 TFLEVLEEFP--SLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDG 935
T LEVL +FP + + +LL +P+++PR +SI+SS P+ + + VAVV + TR
Sbjct: 352 TILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLK 411
Query: 936 QGPLHHGVCSTWLNSLKP-QDPV--PCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSF 992
+ G+CS+WL SL P Q PV P +VR S PE P P I++GPGTG+APFR+
Sbjct: 412 EP--RRGLCSSWLASLDPGQGPVRVPLWVRPGS-LAFPETPDTPVIMVGPGTGVAPFRAA 468
Query: 993 WQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSR----- 1047
Q+R+ Q L FGCR D+D ++ E E+ ++ L + A+SR
Sbjct: 469 IQERVAQGQTGNF------LFFGCRWRDQDFYWEAEWQELEKRDCLTLI-PAFSREQPPA 521
Query: 1048 ---LPGKPKVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVR-MARDVAHTLKQLVAAKL 1103
+ KVYVQ LR +L S V +L ++ + Y+ G+ + M DV+ L + +
Sbjct: 522 LFSALQEQKVYVQHRLR-ELGSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEG 580
Query: 1104 KLNEEQVEDYFFQLKSQKRYHED 1126
L Y +L+ +R+ +
Sbjct: 581 GLCSPDAAAYLARLQQTRRFQTE 603
>gi|221316709 NADPH dependent diflavin oxidoreductase 1 isoform c
[Homo sapiens]
Length = 590
Score = 183 bits (465), Expect = 7e-46
Identities = 174/615 (28%), Positives = 290/615 (47%), Gaps = 58/615 (9%)
Query: 538 RVTILFATETGKSEALAWDLGA-----LFSCAFNPKVVCMDKYRLSCLEEERLLLVVTST 592
++ +LF ++TG ++ ++ LG C +V +D Y + L E L++ V +T
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGC----RVQALDSYPVVNLINEPLVIFVCAT 60
Query: 593 FGNGDCPGNGEKLKKSLFMLKELNN----KFRYAVFGLGSSMYPRFCAFAHDIDQKLSHL 648
G GD P N + + +F K L + + +AV GLG S Y +F A + ++L L
Sbjct: 61 TGQGDPPDNMKNFWRFIFR-KNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQL 119
Query: 649 GASQLTPMGEGDELS--GQEDAFRSWAVQTFKAACETFD-----VRGKQHIQIPKLYTSN 701
G S L P+ GD+ G + A W + + + +P +T
Sbjct: 120 GGSALLPVCLGDDQHELGPDAAVDPWLRDLWDRVLGLYPPPPGLTEIPPGVPLPSKFT-- 177
Query: 702 VTWDPHHYRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCED 761
+ + + Q + + F + S Q + P+ + L+E
Sbjct: 178 LLFLQEAPSTGSEGQRVAHPGSQEPPSESKPFLAPMISNQRVTGPSHFQDVRLIEFDIL- 236
Query: 762 GQGLNYLPGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLP- 820
G G+++ G+ + + P N A VQ + V G P Q L+ + S S RLP
Sbjct: 237 GSGISFAAGDVVLIQPSNSAAHVQRFCQ--VLGLDPDQLFMLQPREPDVS---SPTRLPQ 291
Query: 821 PCSLSQALTYFLDITTPPTQLLLQKLAQVATEEPERQRL-EALCQPSEYSKWKFTNSP-- 877
PCS+ ++++LDI + P + + LA ++ E ER++L E + +++ N P
Sbjct: 292 PCSMRHLVSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRR 351
Query: 878 TFLEVLEEFP--SLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDG 935
T LEVL +FP + + +LL +P+++PR +SI+SS + + VAVV + TR
Sbjct: 352 TILEVLCDFPHTAAAIPPDYLLDLIPVIRPRAFSIASS-------LLILVAVVQFQTRLK 404
Query: 936 QGPLHHGVCSTWLNSLKP-QDPV--PCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSF 992
+ G+CS+WL SL P Q PV P +VR S PE P P I++GPGTG+APFR+
Sbjct: 405 EP--RRGLCSSWLASLDPGQGPVRVPLWVRPGS-LAFPETPDTPVIMVGPGTGVAPFRAA 461
Query: 993 WQQRLHDSQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKP 1052
Q+R+ Q L FGCR D+D ++ E E+ ++ L + A+SR +
Sbjct: 462 IQERVAQGQTGNF------LFFGCRWRDQDFYWEAEWQELEKRDCLTLI-PAFSR-EQEQ 513
Query: 1053 KVYVQDILRQQLASEVLRVLHKEPGHLYVCGDVR-MARDVAHTLKQLVAAKLKLNEEQVE 1111
KVYVQ LR +L S V +L ++ + Y+ G+ + M DV+ L + + L
Sbjct: 514 KVYVQHRLR-ELGSLVWELLDRQGAYFYLAGNAKSMPADVSEALMSIFQEEGGLCSPDAA 572
Query: 1112 DYFFQLKSQKRYHED 1126
Y +L+ +R+ +
Sbjct: 573 AYLARLQQTRRFQTE 587
>gi|221316707 NADPH dependent diflavin oxidoreductase 1 isoform d
[Homo sapiens]
Length = 521
Score = 176 bits (446), Expect = 1e-43
Identities = 166/556 (29%), Positives = 265/556 (47%), Gaps = 70/556 (12%)
Query: 538 RVTILFATETGKSEALAWDLGA-----LFSCAFNPKVVCMDKYRLSCLEEERLLLVVTST 592
++ +LF ++TG ++ ++ LG C +V +D Y + L E L++ V +T
Sbjct: 5 QLLVLFGSQTGTAQDVSERLGREARRRRLGC----RVQALDSYPVVNLINEPLVIFVCAT 60
Query: 593 FGNGDCPGNGEKLKKSLFMLKELNN----KFRYAVFGLGSSMYPRFCAFAHDIDQKLSHL 648
G GD P N + + +F K L + + +AV GLG S Y +F A + ++L L
Sbjct: 61 TGQGDPPDNMKNFWRFIFR-KNLPSTALCQMDFAVLGLGDSSYAKFNFVAKKLHRRLLQL 119
Query: 649 GASQLTPMGEGDELSGQEDAFRSWAVQTFKAACETFDVRGKQHIQIPKLYTSNVTWDPHH 708
G S L P+ GD+ E S F + G++ P
Sbjct: 120 GGSALLPVCLGDDQ--HELGLPSKFTLLFLQEAPSTGSEGQRVAH------------PGS 165
Query: 709 YRLVQDSQPLDLSKALSSMHAKNVFTMRLKSRQNLQSPTSSRATILVELSCEDGQGLNYL 768
+S+P F + S Q + P+ + L+E G G+++
Sbjct: 166 QEPPSESKP---------------FLAPMISNQRVTGPSHFQDVRLIEFDIL-GSGISFA 209
Query: 769 PGEHLGVCPGNQPALVQGILERVVDGPTPHQTVRLEALDESGSYWVSDKRLP-PCSLSQA 827
G+ + + P N A VQ + V G P Q L+ + S S RLP PCS+
Sbjct: 210 AGDVVLIQPSNSAAHVQRFCQ--VLGLDPDQLFMLQPREPDVS---SPTRLPQPCSMRHL 264
Query: 828 LTYFLDITTPPTQLLLQKLAQVATEEPERQRL-EALCQPSEYSKWKFTNSP--TFLEVLE 884
++++LDI + P + + LA ++ E ER++L E + +++ N P T LEVL
Sbjct: 265 VSHYLDIASVPRRSFFELLACLSLHELEREKLLEFSSAQGQEELFEYCNRPRRTILEVLC 324
Query: 885 EFP--SLRVSAGFLLSQLPILKPRFYSISSSRDHTPTEIHLTVAVVTYHTRDGQGPLHHG 942
+FP + + +LL +P+++PR +SI+SS P+ + + VAVV + TR + G
Sbjct: 325 DFPHTAAAIPPDYLLDLIPVIRPRAFSIASSLLTHPSRLQILVAVVQFQTRLKEP--RRG 382
Query: 943 VCSTWLNSLKP-QDPV--PCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHD 999
+CS+WL SL P Q PV P +VR S PE P P I++GPGTG+APFR+ Q+R+
Sbjct: 383 LCSSWLASLDPGQGPVRVPLWVRPGS-LAFPETPDTPVIMVGPGTGVAPFRAAIQERVAQ 441
Query: 1000 SQHKGVRGGRMTLVFGCRRPDEDHIYQEEMLEMAQKGVLHAVHTAYSRLPGKPKVYVQDI 1059
Q L FGCR D+D ++ E E+ ++ L + A+SR + KVYVQ
Sbjct: 442 GQTGNF------LFFGCRWRDQDFYWEAEWQELEKRDCLTLI-PAFSR-EQEQKVYVQHR 493
Query: 1060 LRQQLASEVLRVLHKE 1075
LR +L S V +L ++
Sbjct: 494 LR-ELGSLVWELLDRQ 508
>gi|50726981 radical S-adenosyl methionine and flavodoxin domains 1
[Homo sapiens]
Length = 732
Score = 37.0 bits (84), Expect = 0.11
Identities = 24/60 (40%), Positives = 32/60 (53%), Gaps = 7/60 (11%)
Query: 620 RYAVFGLGSSMY-PRFCAFAHDIDQKLSHLGASQLTPMGEGD------ELSGQEDAFRSW 672
RYAVFGLG+S Y F ++D+ L LGA ++ GEGD + E FR+W
Sbjct: 173 RYAVFGLGNSAYASHFNKVGKNVDKWLWMLGAHRVMSRGEGDCDVVKSKHGSIEADFRAW 232
>gi|18496983 CAP-GLY domain containing linker protein 3 [Homo sapiens]
Length = 547
Score = 33.5 bits (75), Expect = 1.2
Identities = 28/89 (31%), Positives = 34/89 (38%)
Query: 953 PQDPVPCFVRNASGFHLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDSQHKGVRGGRMTL 1012
P P P A F P DP+ IL P T I + +Q + QHK G L
Sbjct: 45 PSAPAPLPKDYAFTFFDPNDPACQEILFDPQTTIPELFAIVRQWVPQVQHKIDVIGNEIL 104
Query: 1013 VFGCRRPDEDHIYQEEMLEMAQKGVLHAV 1041
GC D D + +L A K H V
Sbjct: 105 RRGCHVNDRDGLTDMTLLHYACKAGAHGV 133
>gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens]
Length = 794
Score = 31.6 bits (70), Expect = 4.5
Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 6/58 (10%)
Query: 215 RSCSTAREMFEHICRHVRYSTNNGNIRSAITVFPQRSDGKHDFRVWNAQLIRYAGYQM 272
RSC TA E+F+++C R+S +T + DG ++ V L+ GY++
Sbjct: 537 RSCHTAVELFKNVCERGRWS------ERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEV 588
>gi|224282123 tRNA-yW synthesizing protein 1 homolog B isoform 1
[Homo sapiens]
Length = 668
Score = 31.6 bits (70), Expect = 4.5
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 7/60 (11%)
Query: 620 RYAVFGLGSSMY-PRFCAFAHDIDQKLSHLGASQLTPMGEGD------ELSGQEDAFRSW 672
R AVFGLG+S Y F ++D+ L LG ++ GEGD + E FR+W
Sbjct: 127 RDAVFGLGNSAYASHFNKVGKNVDKWLWMLGVHRVMSRGEGDCDVVKSKHGSIEANFRAW 186
>gi|157426896 tripartite motif-containing 10 isoform 2 [Homo sapiens]
Length = 395
Score = 31.6 bits (70), Expect = 4.5
Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 12/75 (16%)
Query: 959 CFVRNASGFHLPEDP--SHPCILIGPGTGIAPFRSFWQQRLHDSQ----------HKGVR 1006
CF + H+ DP SHP +L+ A F WQ + Q H G+
Sbjct: 302 CFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGIT 361
Query: 1007 GGRMTLVFGCRRPDE 1021
GGR T V+ R P +
Sbjct: 362 GGRHTWVWMARVPGD 376
>gi|29570798 phosphoribosyl pyrophosphate amidotransferase
proprotein [Homo sapiens]
Length = 517
Score = 30.8 bits (68), Expect = 7.8
Identities = 13/42 (30%), Positives = 25/42 (59%)
Query: 163 LARVEAVTKEIETTGTYQLTGDELIFATKQAWRNAPRCIGRI 204
+AR++ + KE T + + ++I+A + + N P CIGR+
Sbjct: 170 VARIKNLMKEAPTAYSLLIMHRDVIYAVRDPYGNRPLCIGRL 211
>gi|68348723 zinc finger protein 711 [Homo sapiens]
Length = 761
Score = 30.8 bits (68), Expect = 7.8
Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 2/63 (3%)
Query: 640 DIDQKLSHLGASQLTPMGEGDELSGQEDAFRSWAVQT--FKAACETFDVRGKQHIQIPKL 697
D+ +KL H+G + L +G + +ED F S ++ FKA E G I
Sbjct: 210 DVGEKLEHMGNTPLKIGSDGSQEDAKEDGFGSEVIKVYIFKAEAEDDVEIGGTEIVTESE 269
Query: 698 YTS 700
YTS
Sbjct: 270 YTS 272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,056,117
Number of Sequences: 37866
Number of extensions: 2308429
Number of successful extensions: 5231
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 5149
Number of HSP's gapped (non-prelim): 34
length of query: 1153
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1040
effective length of database: 13,968,660
effective search space: 14527406400
effective search space used: 14527406400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.