Guide to the Human Genome
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Search of human proteins with 118600991

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118600991 trafficking protein particle complex 6B isoform 1
[Homo sapiens]
         (158 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118600991 trafficking protein particle complex 6B isoform 1 [...   318   2e-87
gi|28976154 trafficking protein particle complex 6B isoform 2 [H...   248   2e-66
gi|13129120 trafficking protein particle complex 6A [Homo sapiens]    178   1e-45
gi|212720946 BET3 like [Homo sapiens]                                  36   0.012
gi|5901980 heat shock transcription factor 2 binding protein [Ho...    30   0.86 
gi|7656926 trafficking protein particle complex 3 [Homo sapiens]       28   2.5  
gi|9257190 adducin 2 isoform e [Homo sapiens]                          27   5.6  
gi|89276787 adducin 2 isoform b [Homo sapiens]                         27   5.6  
gi|9257192 adducin 2 isoform a [Homo sapiens]                          27   5.6  
gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]                  27   5.6  
gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]                 27   5.6  
gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]                  27   5.6  
gi|33188443 microfilament and actin filament cross-linker protei...    27   7.3  
gi|33188445 microfilament and actin filament cross-linker protei...    27   7.3  
gi|28195388 RAB11 family interacting protein 4 (class II) [Homo ...    27   7.3  
gi|19718769 engulfment and cell motility 2 [Homo sapiens]              27   9.5  
gi|33469947 engulfment and cell motility 2 [Homo sapiens]              27   9.5  

>gi|118600991 trafficking protein particle complex 6B isoform 1
           [Homo sapiens]
          Length = 158

 Score =  318 bits (814), Expect = 2e-87
 Identities = 158/158 (100%), Positives = 158/158 (100%)

Query: 1   MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKD 60
           MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKD
Sbjct: 1   MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKD 60

Query: 61  ELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLA 120
           ELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLA
Sbjct: 61  ELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLA 120

Query: 121 FTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL 158
           FTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL
Sbjct: 121 FTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL 158


>gi|28976154 trafficking protein particle complex 6B isoform 2 [Homo
           sapiens]
          Length = 130

 Score =  248 bits (633), Expect = 2e-66
 Identities = 130/158 (82%), Positives = 130/158 (82%), Gaps = 28/158 (17%)

Query: 1   MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKD 60
           MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKD
Sbjct: 1   MADEALFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKD 60

Query: 61  ELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLA 120
           ELDIMKFICKDFWTTVFKKQIDNLRTNHQ                            YLA
Sbjct: 61  ELDIMKFICKDFWTTVFKKQIDNLRTNHQ----------------------------YLA 92

Query: 121 FTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL 158
           FTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL
Sbjct: 93  FTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQKL 130


>gi|13129120 trafficking protein particle complex 6A [Homo sapiens]
          Length = 173

 Score =  178 bits (452), Expect = 1e-45
 Identities = 90/172 (52%), Positives = 118/172 (68%), Gaps = 15/172 (8%)

Query: 1   MADEALFLLLHNEMVSGVY--------------KSAEQGEVENGRC-ITKLENMGFRVGQ 45
           MAD  LF  LH EMV+ ++              +  E G  +  +  ++ LE MGFRVGQ
Sbjct: 1   MADTVLFEFLHTEMVAELWAHDPDPGPGVSAGLRGEEAGATKGQKMSLSVLEGMGFRVGQ 60

Query: 46  GLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQM 105
            L ER  ++T  F++ELD++KF+CKD W  VF+KQ+D+LRTNHQG YVLQDN F LL  M
Sbjct: 61  ALGERLPRETLAFREELDVLKFLCKDLWVAVFQKQMDSLRTNHQGTYVLQDNSFPLLLPM 120

Query: 106 SAGKQYLEHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKFQVMIQK 157
           ++G QYLE A K+LAFTCGL+RG L  LGI+S+VTA V+++P CKFQV+I K
Sbjct: 121 ASGLQYLEEAPKFLAFTCGLLRGALYTLGIESVVTASVAALPVCKFQVVIPK 172


>gi|212720946 BET3 like [Homo sapiens]
          Length = 181

 Score = 36.2 bits (82), Expect = 0.012
 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 14/141 (9%)

Query: 6   LFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTA-----RFKD 60
           LF+L +  +V+ + K  E+ E  N      L+ MG+ +G  L+E F   +       + +
Sbjct: 18  LFVLTYGALVAQLCKDYEKDEDVN----QYLDKMGYGIGTRLVEDFLARSCVGRCHSYSE 73

Query: 61  ELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKF-RLLTQMSAGKQYLEHASKYL 119
            +DI+  +    +  +      N  + ++   +L+ N     + ++ AG+  L     Y 
Sbjct: 74  IIDIIAQVAFKMYLGITPSVTCNNSSKNEFSLILEKNPLVEFVEELPAGRSSL----CYC 129

Query: 120 AFTCGLIRGGLSNLGIKSIVT 140
              CG+IRG L  + + + VT
Sbjct: 130 NLLCGIIRGALEMVHLAADVT 150


>gi|5901980 heat shock transcription factor 2 binding protein [Homo
           sapiens]
          Length = 334

 Score = 30.0 bits (66), Expect = 0.86
 Identities = 28/103 (27%), Positives = 46/103 (44%), Gaps = 15/103 (14%)

Query: 53  KDTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYL 112
           K+  R + EL+ +K  C+ F   +   Q DN+R   +        K  L  Q++  KQ L
Sbjct: 62  KNLERKEQELEQLKMDCEHFKARLETVQADNIREKKE--------KLALRQQLNEAKQQL 113

Query: 113 ----EHASKYLAFTCGLIRGGLSNLGIKSIVTAEVSSMPACKF 151
               E+ ++  A  C L+ G  S+   + +V A +    A KF
Sbjct: 114 LQQAEYCTEMGAAACTLLWGVSSS---EEVVKAILGGDKALKF 153


>gi|7656926 trafficking protein particle complex 3 [Homo sapiens]
          Length = 180

 Score = 28.5 bits (62), Expect = 2.5
 Identities = 28/130 (21%), Positives = 55/130 (42%), Gaps = 13/130 (10%)

Query: 6   LFLLLHNEMVSGVYKSAEQGEVENGRCITKLENMGFRVGQGLIERF--TKDTAR---FKD 60
           LF L +  +V+ + K  E  E  N     +L+ MGF +G  LIE F    +  R   F++
Sbjct: 18  LFTLTYGALVTQLCKDYENDEDVN----KQLDKMGFNIGVRLIEDFLARSNVGRCHDFRE 73

Query: 61  ELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLA 120
             D++  +    +  +     +      +   +L++N      ++      L +++    
Sbjct: 74  TADVIAKVAFKMYLGITPSITNWSPAGDEFSLILENNPLVDFVELPDNHSSLIYSN---- 129

Query: 121 FTCGLIRGGL 130
             CG++RG L
Sbjct: 130 LLCGVLRGAL 139


>gi|9257190 adducin 2 isoform e [Homo sapiens]
          Length = 643

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 13/48 (27%), Positives = 24/48 (50%)

Query: 17  GVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDI 64
           G  + +  GE E    +  L+N+G+R G      F ++  + K E++I
Sbjct: 353 GPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEI 400


>gi|89276787 adducin 2 isoform b [Homo sapiens]
          Length = 559

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 13/48 (27%), Positives = 24/48 (50%)

Query: 17  GVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDI 64
           G  + +  GE E    +  L+N+G+R G      F ++  + K E++I
Sbjct: 353 GPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEI 400


>gi|9257192 adducin 2 isoform a [Homo sapiens]
          Length = 726

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 13/48 (27%), Positives = 24/48 (50%)

Query: 17  GVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDI 64
           G  + +  GE E    +  L+N+G+R G      F ++  + K E++I
Sbjct: 353 GPMQKSRLGEHEFEALMRMLDNLGYRTGYTYRHPFVQEKTKHKSEVEI 400


>gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 12/48 (25%), Positives = 25/48 (52%)

Query: 17  GVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDI 64
           G ++  + GE+E    +  L+N+G+R G        ++  R K +++I
Sbjct: 359 GSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEI 406


>gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 12/48 (25%), Positives = 25/48 (52%)

Query: 17  GVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDI 64
           G ++  + GE+E    +  L+N+G+R G        ++  R K +++I
Sbjct: 359 GSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEI 406


>gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]
          Length = 706

 Score = 27.3 bits (59), Expect = 5.6
 Identities = 12/48 (25%), Positives = 25/48 (52%)

Query: 17  GVYKSAEQGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDI 64
           G ++  + GE+E    +  L+N+G+R G        ++  R K +++I
Sbjct: 359 GSHQKWKVGEIEFEGLMRTLDNLGYRTGYAYRHPLIREKPRHKSDVEI 406


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 26.9 bits (58), Expect = 7.3
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 4/42 (9%)

Query: 54   DTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQ 95
            D    KD+L+ MK    +F   V+++QI+  + NHQG  +L+
Sbjct: 4689 DLNTVKDQLNEMK----EFKVEVYQQQIEMEKLNHQGELMLK 4726


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 26.9 bits (58), Expect = 7.3
 Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 4/42 (9%)

Query: 54   DTARFKDELDIMKFICKDFWTTVFKKQIDNLRTNHQGIYVLQ 95
            D    KD+L+ MK    +F   V+++QI+  + NHQG  +L+
Sbjct: 4187 DLNTVKDQLNEMK----EFKVEVYQQQIEMEKLNHQGELMLK 4224


>gi|28195388 RAB11 family interacting protein 4 (class II) [Homo
           sapiens]
          Length = 637

 Score = 26.9 bits (58), Expect = 7.3
 Identities = 26/111 (23%), Positives = 49/111 (44%), Gaps = 22/111 (19%)

Query: 13  EMVSGVYKSAEQGEVENGRCITKLENMGFRVG---QGLIERFTKDTARFKDELDIMKFIC 69
           E+++   +  E+   E    +T+L++   ++    Q + +R    + R KDE+D+     
Sbjct: 420 ELLNARVQQLEEENTELRTTVTRLKSQTEKLDEERQRMSDRLEDTSLRLKDEMDL----- 474

Query: 70  KDFWTTVFKKQIDNLRTNHQGIYVLQDNKFRLLTQ--MSAGKQYLEHASKY 118
                  +K+ +D LR N      L+  K R  TQ  +   ++ LEH   Y
Sbjct: 475 -------YKRMMDKLRQNR-----LEFQKEREATQELIEDLRKELEHLQMY 513


>gi|19718769 engulfment and cell motility 2 [Homo sapiens]
          Length = 720

 Score = 26.6 bits (57), Expect = 9.5
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 14/99 (14%)

Query: 24  QGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDN 83
           + +++NG  I +L     R  + L+ER    ++  +  LD MK + K      F  +  N
Sbjct: 66  RSDIKNGT-ILQLAISPSRAARQLMER--TQSSNMETRLDAMKELAKLSADVTFATEFIN 122

Query: 84  LRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFT 122
           +     GI VL     RL+    +G + L H S+ LAFT
Sbjct: 123 M----DGIIVLT----RLV---ESGTKLLSHYSEMLAFT 150


>gi|33469947 engulfment and cell motility 2 [Homo sapiens]
          Length = 720

 Score = 26.6 bits (57), Expect = 9.5
 Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 14/99 (14%)

Query: 24  QGEVENGRCITKLENMGFRVGQGLIERFTKDTARFKDELDIMKFICKDFWTTVFKKQIDN 83
           + +++NG  I +L     R  + L+ER    ++  +  LD MK + K      F  +  N
Sbjct: 66  RSDIKNGT-ILQLAISPSRAARQLMER--TQSSNMETRLDAMKELAKLSADVTFATEFIN 122

Query: 84  LRTNHQGIYVLQDNKFRLLTQMSAGKQYLEHASKYLAFT 122
           +     GI VL     RL+    +G + L H S+ LAFT
Sbjct: 123 M----DGIIVLT----RLV---ESGTKLLSHYSEMLAFT 150


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,948,404
Number of Sequences: 37866
Number of extensions: 183236
Number of successful extensions: 399
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 386
Number of HSP's gapped (non-prelim): 20
length of query: 158
length of database: 18,247,518
effective HSP length: 94
effective length of query: 64
effective length of database: 14,688,114
effective search space: 940039296
effective search space used: 940039296
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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