Guide to the Human Genome
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Search of human proteins with 10835159

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
         (402 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]          802   0.0  
gi|211904156 plasminogen activator inhibitor type 1, member 2 is...   300   2e-81
gi|211904154 plasminogen activator inhibitor type 1, member 2 is...   300   2e-81
gi|211904152 plasminogen activator inhibitor type 1, member 2 is...   300   2e-81
gi|24307907 plasminogen activator inhibitor type 1, member 2 iso...   295   4e-80
gi|170295807 neuroserpin precursor [Homo sapiens]                     229   3e-60
gi|4826904 neuroserpin precursor [Homo sapiens]                       229   3e-60
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   206   3e-53
gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]   188   8e-48
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   182   4e-46
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   182   4e-46
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s...   180   2e-45
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   180   2e-45
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (...   179   4e-45
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom...   176   3e-44
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   175   7e-44
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   173   2e-43
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ...   171   1e-42
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o...   171   1e-42
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom...   170   2e-42
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo...   170   2e-42
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo...   170   2e-42
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo...   170   2e-42

>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
          Length = 402

 Score =  802 bits (2071), Expect = 0.0
 Identities = 402/402 (100%), Positives = 402/402 (100%)

Query: 1   MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY 60
           MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY
Sbjct: 1   MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPY 60

Query: 61  GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI 120
           GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI
Sbjct: 61  GVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAI 120

Query: 121 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV 180
           FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV
Sbjct: 121 FVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAV 180

Query: 181 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD 240
           DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD
Sbjct: 181 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD 240

Query: 241 GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK 300
           GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK
Sbjct: 241 GHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPK 300

Query: 301 FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS 360
           FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS
Sbjct: 301 FSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASS 360

Query: 361 STAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402
           STAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP
Sbjct: 361 STAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402


>gi|211904156 plasminogen activator inhibitor type 1, member 2
           isoform c precursor [Homo sapiens]
          Length = 409

 Score =  300 bits (767), Expect = 2e-81
 Identities = 157/379 (41%), Positives = 234/379 (61%), Gaps = 3/379 (0%)

Query: 25  HHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAA 84
           H  P  +  L S+ G++VF Q+ ++    N+V SP+G+ASVL MLQL   G T++Q+   
Sbjct: 33  HFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMV 92

Query: 85  MGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTV 144
           M + ++  G+   L+ + K ++   NKD ++  +A+FV+   ++   F+     +F+  V
Sbjct: 93  MRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 150

Query: 145 KQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQ-LTRLVLVNALYFNGQWKTPFP 203
           + V+F +   A   IN WVK  T+ MI NLL    +D  LTRLVLVNA+YF G WK+ F 
Sbjct: 151 RNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQ 210

Query: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAP 263
             +T +R F  +DG +  VPM+AQ + F     + P+  +Y+ +ELPYHG+++SM IA P
Sbjct: 211 PENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALP 270

Query: 264 YEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323
            E   PLSA+   +S + I  W   M      ++LPKF+   + DL++PL+ LG+TDMF 
Sbjct: 271 TESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFD 330

Query: 324 QFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLF 383
             +A+F  ++  E LHV+  LQK KIEV+E GT AS++T  I+ AR +P   I+DRPFLF
Sbjct: 331 SSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLF 390

Query: 384 VVRHNPTGTVLFMGQVMEP 402
            +RHNPTG VLFMGQ+ +P
Sbjct: 391 FIRHNPTGAVLFMGQINKP 409


>gi|211904154 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  300 bits (767), Expect = 2e-81
 Identities = 157/379 (41%), Positives = 234/379 (61%), Gaps = 3/379 (0%)

Query: 25  HHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAA 84
           H  P  +  L S+ G++VF Q+ ++    N+V SP+G+ASVL MLQL   G T++Q+   
Sbjct: 21  HFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMV 80

Query: 85  MGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTV 144
           M + ++  G+   L+ + K ++   NKD ++  +A+FV+   ++   F+     +F+  V
Sbjct: 81  MRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 138

Query: 145 KQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQ-LTRLVLVNALYFNGQWKTPFP 203
           + V+F +   A   IN WVK  T+ MI NLL    +D  LTRLVLVNA+YF G WK+ F 
Sbjct: 139 RNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQ 198

Query: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAP 263
             +T +R F  +DG +  VPM+AQ + F     + P+  +Y+ +ELPYHG+++SM IA P
Sbjct: 199 PENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALP 258

Query: 264 YEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323
            E   PLSA+   +S + I  W   M      ++LPKF+   + DL++PL+ LG+TDMF 
Sbjct: 259 TESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFD 318

Query: 324 QFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLF 383
             +A+F  ++  E LHV+  LQK KIEV+E GT AS++T  I+ AR +P   I+DRPFLF
Sbjct: 319 SSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLF 378

Query: 384 VVRHNPTGTVLFMGQVMEP 402
            +RHNPTG VLFMGQ+ +P
Sbjct: 379 FIRHNPTGAVLFMGQINKP 397


>gi|211904152 plasminogen activator inhibitor type 1, member 2
           isoform b precursor [Homo sapiens]
          Length = 397

 Score =  300 bits (767), Expect = 2e-81
 Identities = 157/379 (41%), Positives = 234/379 (61%), Gaps = 3/379 (0%)

Query: 25  HHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAA 84
           H  P  +  L S+ G++VF Q+ ++    N+V SP+G+ASVL MLQL   G T++Q+   
Sbjct: 21  HFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMV 80

Query: 85  MGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTV 144
           M + ++  G+   L+ + K ++   NKD ++  +A+FV+   ++   F+     +F+  V
Sbjct: 81  MRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 138

Query: 145 KQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQ-LTRLVLVNALYFNGQWKTPFP 203
           + V+F +   A   IN WVK  T+ MI NLL    +D  LTRLVLVNA+YF G WK+ F 
Sbjct: 139 RNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQ 198

Query: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAP 263
             +T +R F  +DG +  VPM+AQ + F     + P+  +Y+ +ELPYHG+++SM IA P
Sbjct: 199 PENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALP 258

Query: 264 YEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323
            E   PLSA+   +S + I  W   M      ++LPKF+   + DL++PL+ LG+TDMF 
Sbjct: 259 TESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFD 318

Query: 324 QFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLF 383
             +A+F  ++  E LHV+  LQK KIEV+E GT AS++T  I+ AR +P   I+DRPFLF
Sbjct: 319 SSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLF 378

Query: 384 VVRHNPTGTVLFMGQVMEP 402
            +RHNPTG VLFMGQ+ +P
Sbjct: 379 FIRHNPTGAVLFMGQINKP 397


>gi|24307907 plasminogen activator inhibitor type 1, member 2
           isoform a precursor [Homo sapiens]
          Length = 398

 Score =  295 bits (756), Expect = 4e-80
 Identities = 157/380 (41%), Positives = 234/380 (61%), Gaps = 4/380 (1%)

Query: 25  HHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAA 84
           H  P  +  L S+ G++VF Q+ ++    N+V SP+G+ASVL MLQL   G T++Q+   
Sbjct: 21  HFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMV 80

Query: 85  MGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTV 144
           M + ++  G+   L+ + K ++   NKD ++  +A+FV+   ++   F+     +F+  V
Sbjct: 81  MRYGVN--GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 138

Query: 145 KQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQ-LTRLVLVNALYFNGQWKTPFP 203
           + V+F +   A   IN WVK  T+ MI NLL    +D  LTRLVLVNA+YF G WK+ F 
Sbjct: 139 RNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQ 198

Query: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAP 263
             +T +R F  +DG +  VPM+AQ + F     + P+  +Y+ +ELPYHG+++SM IA P
Sbjct: 199 PENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALP 258

Query: 264 YEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323
            E   PLSA+   +S + I  W   M      ++LPKF+   + DL++PL+ LG+TDMF 
Sbjct: 259 TESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFD 318

Query: 324 QFQADFTSL-SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFL 382
             +A+F  + +  E LHV+  LQK KIEV+E GT AS++T  I+ AR +P   I+DRPFL
Sbjct: 319 SSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFL 378

Query: 383 FVVRHNPTGTVLFMGQVMEP 402
           F +RHNPTG VLFMGQ+ +P
Sbjct: 379 FFIRHNPTGAVLFMGQINKP 398


>gi|170295807 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  229 bits (584), Expect = 3e-60
 Identities = 124/373 (33%), Positives = 214/373 (57%), Gaps = 8/373 (2%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMA 95
           +D  V ++ ++    +D N++FSP  +A  + M++L   G TQ++I+ +MG+     G  
Sbjct: 27  ADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEE 86

Query: 96  PA-LRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVER 154
            + L+     +    ++  +   +++FVQ    + + F+    + F + V  VDFS+   
Sbjct: 87  FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVA 146

Query: 155 ARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHK 214
               IN WV+ +T  ++ +L+     D  T L L+NA+YF G WK+ F   +T    F K
Sbjct: 147 VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTK 206

Query: 215 SDGSTVSVPMMAQTNKFNYTEF---TTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLS 271
            D S V +PMM Q  +F Y EF   +   G  Y +LE+PY GD +SM +     +EVPL+
Sbjct: 207 DDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS-RQEVPLA 265

Query: 272 ALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTS 331
            L  ++ AQL+  W  ++ +    + LP+F++E E+DL+  L+ LG+T++F +  A+ T 
Sbjct: 266 TLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-DANLTG 324

Query: 332 LSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAP--EEIIMDRPFLFVVRHNP 389
           LSD + + +++A+ K  +EVNE G+ A++ + +I  +RMA    ++I+D PF F++R+  
Sbjct: 325 LSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRR 384

Query: 390 TGTVLFMGQVMEP 402
           TGT+LFMG+VM P
Sbjct: 385 TGTILFMGRVMHP 397


>gi|4826904 neuroserpin precursor [Homo sapiens]
          Length = 410

 Score =  229 bits (584), Expect = 3e-60
 Identities = 124/373 (33%), Positives = 214/373 (57%), Gaps = 8/373 (2%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMA 95
           +D  V ++ ++    +D N++FSP  +A  + M++L   G TQ++I+ +MG+     G  
Sbjct: 27  ADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEE 86

Query: 96  PA-LRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVER 154
            + L+     +    ++  +   +++FVQ    + + F+    + F + V  VDFS+   
Sbjct: 87  FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVA 146

Query: 155 ARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHK 214
               IN WV+ +T  ++ +L+     D  T L L+NA+YF G WK+ F   +T    F K
Sbjct: 147 VANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTK 206

Query: 215 SDGSTVSVPMMAQTNKFNYTEF---TTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLS 271
            D S V +PMM Q  +F Y EF   +   G  Y +LE+PY GD +SM +     +EVPL+
Sbjct: 207 DDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLS-RQEVPLA 265

Query: 272 ALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTS 331
            L  ++ AQL+  W  ++ +    + LP+F++E E+DL+  L+ LG+T++F +  A+ T 
Sbjct: 266 TLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-DANLTG 324

Query: 332 LSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAP--EEIIMDRPFLFVVRHNP 389
           LSD + + +++A+ K  +EVNE G+ A++ + +I  +RMA    ++I+D PF F++R+  
Sbjct: 325 LSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRR 384

Query: 390 TGTVLFMGQVMEP 402
           TGT+LFMG+VM P
Sbjct: 385 TGTILFMGRVMHP 397


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  206 bits (524), Expect = 3e-53
 Identities = 121/370 (32%), Positives = 201/370 (54%), Gaps = 7/370 (1%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMA 95
           ++F V ++Q+V+ + KD N++FSP G+  VL M+QL   G+ QQQI+  +  +    G  
Sbjct: 27  TEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEE 85

Query: 96  P-ALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVER 154
              L+  +  +     +   +  +A+++Q    + + ++      F+S +K VDF + + 
Sbjct: 86  FFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQDAKA 145

Query: 155 ARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHK 214
              +I+ WV+  T G I ++        LTRLVLVNA+YF G WK  F    T    F K
Sbjct: 146 CAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLINFTK 205

Query: 215 SDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALT 274
            +GSTV +PMM    +  Y  F+    + Y +LEL Y GD  S+ I  P E  + +  + 
Sbjct: 206 KNGSTVKIPMMKALLRTKYGYFSESSLN-YQVLELSYKGDEFSLIIILPAE-GMDIEEVE 263

Query: 275 NILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD 334
            +++AQ I  W   M      + LP+F +E +VD +  L +L +T++F     D + ++D
Sbjct: 264 KLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIF-SGGCDLSGITD 322

Query: 335 QEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARM--APEEIIMDRPFLFVVRHNPTGT 392
              ++V+Q  QKV  E+NE G+ A++ST + +   M  A  + I + PFLF+++HNPT +
Sbjct: 323 SSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHNPTES 382

Query: 393 VLFMGQVMEP 402
           +LFMG+V  P
Sbjct: 383 ILFMGRVTNP 392


>gi|157674356 nexin-related serine protease inhibitor [Homo sapiens]
          Length = 424

 Score =  188 bits (477), Expect = 8e-48
 Identities = 116/371 (31%), Positives = 189/371 (50%), Gaps = 5/371 (1%)

Query: 34  LASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKG 93
           L ++F + ++Q VA    + N V SP GV+  L +LQ    G T QQ+  A+G+ + DK 
Sbjct: 29  LKTEFALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKR 88

Query: 94  MAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVE 153
           +   L  +Y  L       E+    ++FVQ    L   F+ H      S+++  D SE  
Sbjct: 89  VKDFLHAVYATLPTSSQGTEMELACSLFVQVGTPLSPCFVEHVSWWANSSLEPADLSEPN 148

Query: 154 RARFIINDWVKTHTKGM-ISNLLGKGAVDQLT----RLVLVNALYFNGQWKTPFPDSSTH 208
                 ++     T G   S   G    +Q++    +LVLV+ + F G W+  F  + T 
Sbjct: 149 STAIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQLVLVSTMSFQGTWRKRFSSTDTQ 208

Query: 209 RRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEV 268
              F  + G  + VPMM QT + NY +F    GH   +LELPY G  +S+F+  P +K+ 
Sbjct: 209 ILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVGVLELPYLGSAVSLFLVLPRDKDT 268

Query: 269 PLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQAD 328
           PLS +   L+A  I  W  ++ R    + LP+F ++ + +L+  L + G+TD+F   +A+
Sbjct: 269 PLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLKSILNSWGVTDLFDPLKAN 328

Query: 329 FTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHN 388
              +S Q+  +V++A+ K KIEV E GT AS +TA+++  R        DRPF++ +R  
Sbjct: 329 LKGISGQDGFYVSEAIHKAKIEVLEEGTKASGATALLLLKRSRIPIFKADRPFIYFLREP 388

Query: 389 PTGTVLFMGQV 399
            TG  +F  ++
Sbjct: 389 NTGITVFFDRI 399


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  182 bits (463), Expect = 4e-46
 Identities = 117/370 (31%), Positives = 193/370 (52%), Gaps = 11/370 (2%)

Query: 38  FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPA 97
           F + +F+ + +    RNV FSP  ++S LAM+ +   G T  Q+  A+     D  +   
Sbjct: 11  FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL-YKDGDIHRG 69

Query: 98  LRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSE-VERAR 156
            + L  E+     +  + T + +F ++    +  F  +  + +++ ++++ F+E  E  R
Sbjct: 70  FQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECR 129

Query: 157 FIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSD 216
             INDWV   T+G IS +L  G VD LT+LVLVNA+YF G+W   F    T   LF K++
Sbjct: 130 KHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLF-KTN 188

Query: 217 GSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNI 276
               +V MM +  KF   +    D  +  +LELPY  + LSM I  P +    L+ +   
Sbjct: 189 EEKKTVQMMFKEAKF---KMGYADEVHTQVLELPYVEEELSMVILLP-DDNTDLAVVEKA 244

Query: 277 LSAQLISHWKGN--MTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD 334
           L+ +    W  +  +T+    + LP+  LE   DL   L  LGM D F + +ADF+ +S 
Sbjct: 245 LTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMST 304

Query: 335 QEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEE--IIMDRPFLFVVRHNPTGT 392
           ++ + +++   K  +EVNE GT A+++TAV+ ++R +  E     D PFLF +RH+ T  
Sbjct: 305 EKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNC 364

Query: 393 VLFMGQVMEP 402
           +LF G+   P
Sbjct: 365 ILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  182 bits (463), Expect = 4e-46
 Identities = 117/370 (31%), Positives = 193/370 (52%), Gaps = 11/370 (2%)

Query: 38  FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPA 97
           F + +F+ + +    RNV FSP  ++S LAM+ +   G T  Q+  A+     D  +   
Sbjct: 11  FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL-YKDGDIHRG 69

Query: 98  LRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSE-VERAR 156
            + L  E+     +  + T + +F ++    +  F  +  + +++ ++++ F+E  E  R
Sbjct: 70  FQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECR 129

Query: 157 FIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSD 216
             INDWV   T+G IS +L  G VD LT+LVLVNA+YF G+W   F    T   LF K++
Sbjct: 130 KHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLF-KTN 188

Query: 217 GSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNI 276
               +V MM +  KF   +    D  +  +LELPY  + LSM I  P +    L+ +   
Sbjct: 189 EEKKTVQMMFKEAKF---KMGYADEVHTQVLELPYVEEELSMVILLP-DDNTDLAVVEKA 244

Query: 277 LSAQLISHWKGN--MTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD 334
           L+ +    W  +  +T+    + LP+  LE   DL   L  LGM D F + +ADF+ +S 
Sbjct: 245 LTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMST 304

Query: 335 QEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEE--IIMDRPFLFVVRHNPTGT 392
           ++ + +++   K  +EVNE GT A+++TAV+ ++R +  E     D PFLF +RH+ T  
Sbjct: 305 EKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNC 364

Query: 393 VLFMGQVMEP 402
           +LF G+   P
Sbjct: 365 ILFCGRFSSP 374


>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
           sapiens]
          Length = 464

 Score =  180 bits (457), Expect = 2e-45
 Identities = 107/379 (28%), Positives = 200/379 (52%), Gaps = 17/379 (4%)

Query: 36  SDFGVRVFQQVAQASKDR-NVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGM 94
           S F    +Q +A +  D  N+  SP  +++  AM +L    +T QQ+     F    +  
Sbjct: 88  SRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKT 147

Query: 95  APALRHLYKEL----MGPWNKD-EISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDF 149
           +  +   + +L        NK  ++ + + +F  + L   + +      ++ + ++ +DF
Sbjct: 148 SDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDF 207

Query: 150 SE-VERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTH 208
            E  E++R  IN WV   T+G I++++   A+++LT LVLVN +YF G WK+ F   +T 
Sbjct: 208 KENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTR 267

Query: 209 RRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEV 268
           + LF+K+DG + S  MM Q  KF Y            +LELP+ GD ++M +  P + E 
Sbjct: 268 KELFYKADGESCSASMMYQEGKFRYRRVAEGT----QVLELPFKGDDITMVLILP-KPEK 322

Query: 269 PLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQAD 328
            L+ +   L+ +++  W   +  +  ++ +P+F +E    L++ L+++G+ D+F   ++ 
Sbjct: 323 SLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSK 382

Query: 329 FTSL--SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSAR-MAPEEIIM--DRPFLF 383
              +    ++ L+V+ A  K  +EVNE G+ A++STAV+++ R + P  +    +RPFL 
Sbjct: 383 LPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLV 442

Query: 384 VVRHNPTGTVLFMGQVMEP 402
            +R  P  T++FMG+V  P
Sbjct: 443 FIREVPLNTIIFMGRVANP 461


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  180 bits (457), Expect = 2e-45
 Identities = 121/385 (31%), Positives = 191/385 (49%), Gaps = 33/385 (8%)

Query: 42  VFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFK------------- 88
           +FQQ  + SK+ N+ +SP  + S L M+ L     T QQI   + F              
Sbjct: 15  LFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATY 73

Query: 89  -IDDKGMAPALRHLYKELMGPWNKD----EISTTDAIFVQRDLKLVQGFMPHFFRLFRST 143
            +D  G    + H +++L+  +NK     E+   + +F ++  + +Q ++    + ++++
Sbjct: 74  HVDRSGN---VHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTS 130

Query: 144 VKQVDFSEV-ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPF 202
           V+  DF+   E +R  IN WV++ T   I NL   G +   T LVLVNA+YF GQW+  F
Sbjct: 131 VESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKF 190

Query: 203 PDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAA 262
              +T    F  +  +  SV MM Q N FN   F   +     +LE+PY G  LSM +  
Sbjct: 191 KKENTKEEKFWPNKNTYKSVQMMRQYNSFN---FALLEDVQAKVLEIPYKGKDLSMIVLL 247

Query: 263 PYEKEVPLSALTNILSAQLISHWKG--NMTRLPRLLVLPKFSLETEVDLRKPLENLGMTD 320
           P E +  L  L   L+A+ +  W    NM      L LP+F +E   DL+  L  +GM +
Sbjct: 248 PNEID-GLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVN 306

Query: 321 MFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAP---EEIIM 377
           +F    AD + ++    L V++ L K  +EV E G  A+++TAV+V    +P   EE   
Sbjct: 307 IFNG-DADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCC 365

Query: 378 DRPFLFVVRHNPTGTVLFMGQVMEP 402
           + PFLF +R N T ++LF G+   P
Sbjct: 366 NHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 1 [Homo sapiens]
          Length = 379

 Score =  179 bits (454), Expect = 4e-45
 Identities = 120/381 (31%), Positives = 190/381 (49%), Gaps = 28/381 (7%)

Query: 38  FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPA 97
           F + +F  +++ +   N+  SP+ ++S +AM+ L T G T  Q+     F   ++     
Sbjct: 11  FALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTVEE----- 65

Query: 98  LRHLYKELMGPWNKDEIS----TTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV- 152
           +   ++ L    NK   S      + ++ ++    +  F+    + + + +  VDF    
Sbjct: 66  VHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDFQHAS 125

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E AR  IN WVK  T+G I  LL  G VD +T+LVLVNA+YF G WK  F   +T    F
Sbjct: 126 EDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATTNAPF 185

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYD----ILELPYHGDTLSMFIAAPYEKEV 268
             +     +V MM Q  KF Y       G+  D    +LELPY G+ LSM I  P + E 
Sbjct: 186 RLNKKDRKTVKMMYQKKKFAY-------GYIEDLKCRVLELPYQGEELSMVILLPDDIED 238

Query: 269 PLSALTNI---LSAQLISHW--KGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323
             + L  I   L+ + +  W    N+  +   + LP+F LE    L   L  LG+ D+F 
Sbjct: 239 ESTGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFN 298

Query: 324 QFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVS-ARMAPEE-IIMDRPF 381
             +AD + +S    + +++ + K  +EVNE GT A+++TA I +   + PEE    D PF
Sbjct: 299 SSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPF 358

Query: 382 LFVVRHNPTGTVLFMGQVMEP 402
           LF +RHN +G++LF+G+   P
Sbjct: 359 LFFIRHNSSGSILFLGRFSSP 379


>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
           sapiens]
          Length = 392

 Score =  176 bits (447), Expect = 3e-44
 Identities = 109/387 (28%), Positives = 195/387 (50%), Gaps = 25/387 (6%)

Query: 37  DFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAP 96
           +F + VF+++   +   N+ FS   +   L+M+ L   GET++Q++  + F      + P
Sbjct: 10  EFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHTVDSLKP 69

Query: 97  ALRHL----------------YKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLF 140
             +                  + ++  P +   +S  + ++  + +   Q ++    + +
Sbjct: 70  GFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLSCSEKWY 129

Query: 141 RSTVKQVDFSE-VERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWK 199
           ++ ++ VDF +  E  R  IN WV+  T G ++NL GK  +D  + +VLVNA+YF GQW+
Sbjct: 130 QARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIYFKGQWQ 189

Query: 200 TPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMF 259
             F    T +  F  S+G  V+V MM Q   F       P      +LELPY  + LSM 
Sbjct: 190 NKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQ---MQVLELPYVNNKLSMI 246

Query: 260 IAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLV--LPKFSLETEVDLRKPLENLG 317
           I  P      L  +   L++     W  +   + R +   LP+F LET+ +L   L++LG
Sbjct: 247 ILLPV-GIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKSLG 305

Query: 318 MTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAP--EEI 375
           +TD+F Q +AD + +S  + L++++A+ K  ++V+E GT A+++T   ++ +  P   + 
Sbjct: 306 VTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRAQF 365

Query: 376 IMDRPFLFVVRHNPTGTVLFMGQVMEP 402
             + PFLF +RH  T T+LF G++  P
Sbjct: 366 KANHPFLFFIRHTHTNTILFCGKLASP 392


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  175 bits (443), Expect = 7e-44
 Identities = 119/361 (32%), Positives = 181/361 (50%), Gaps = 20/361 (5%)

Query: 53  RNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKG--MAPALRHLYKELMGPWN 110
           +NV FSP  ++  LAM+ +   G T  Q+   + F     G  +    + L  E+     
Sbjct: 25  KNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKSGGGGDIHQGFQSLLTEVNKTGT 84

Query: 111 KDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDF-SEVERARFIINDWVKTHTKG 169
           +  +   + +F ++    +  F     + +++ ++++DF S VE++R  IN WV   T+G
Sbjct: 85  QYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELDFISAVEKSRKHINTWVAEKTEG 144

Query: 170 MISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTN 229
            I+ LL  G+VD LTRLVLVNA+YF G W   F   +T  RLF  S      V MM + +
Sbjct: 145 KIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENTEERLFKVSKNEEKPVQMMFKQS 204

Query: 230 KFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNM 289
            F  T        +  IL LPY G  L+M I  P ++   L  +   L+ +    W    
Sbjct: 205 TFKKTYI---GEIFTQILVLPYVGKELNMIIMLP-DETTDLRTVEKELTYEKFVEW---- 256

Query: 290 TRLPRL------LVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQA 343
           TRL  +      + LP+F LE   D+   L NLGMTD F   +ADF+ +S Q  L +++ 
Sbjct: 257 TRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADFSGMS-QTDLSLSKV 315

Query: 344 LQKVKIEVNESGTVASSSTAVIVSARMA--PEEIIMDRPFLFVVRHNPTGTVLFMGQVME 401
           + K  +EVNE GT A+++TA I+  R A        D PFLF ++H+ T  +LF G+   
Sbjct: 316 VHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQHSKTNGILFCGRFSS 375

Query: 402 P 402
           P
Sbjct: 376 P 376


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  173 bits (439), Expect = 2e-43
 Identities = 117/382 (30%), Positives = 191/382 (50%), Gaps = 27/382 (7%)

Query: 42  VFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF-KIDDKGMAPA--- 97
           +FQQ  + SK+ N+ +SP  + S L M+ L     T QQI+  + F ++ +     A   
Sbjct: 15  LFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATY 73

Query: 98  -------LRHLYKELMGPWNKD----EISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQ 146
                  + H +++L+  +NK     E+   + +F ++    +Q ++    + ++++V+ 
Sbjct: 74  HVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVES 133

Query: 147 VDFSEV-ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDS 205
           VDF+   E +R  IN WV++ T   I NL+ +G +   T LVLVNA+YF GQW+  F   
Sbjct: 134 VDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKE 193

Query: 206 STHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYE 265
            T    F  +  +  S+ MM Q   F+   F + +     +LE+PY G  LSM +  P E
Sbjct: 194 DTKEEKFWPNKNTYKSIQMMRQYTSFH---FASLEDVQAKVLEIPYKGKDLSMIVLLPNE 250

Query: 266 KEVPLSALTNILSAQLISHWKG--NMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFR 323
            +  L  L   L+A+ +  W    NM      L LP+F +E   DL+  L  +GM D+F 
Sbjct: 251 ID-GLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFN 309

Query: 324 QFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVI---VSARMAPEEIIMDRP 380
              AD + ++    L ++  L K  +EV E G  A+++TAV+    S     EE   + P
Sbjct: 310 G-DADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHP 368

Query: 381 FLFVVRHNPTGTVLFMGQVMEP 402
           FLF +R N T ++LF G+   P
Sbjct: 369 FLFFIRQNKTNSILFYGRFSSP 390


>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  171 bits (432), Expect = 1e-42
 Identities = 120/413 (29%), Positives = 196/413 (47%), Gaps = 56/413 (13%)

Query: 38  FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---------- 87
           F + +F+ +A+AS  +N+  SP+ ++S +AM+ + + G T+ Q+   + F          
Sbjct: 11  FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70

Query: 88  ------------KIDDKGMAP--------------ALRHLYKELMGPWNKDEISTTDAIF 121
                       +   KG  P              + R L   +        + + + +F
Sbjct: 71  MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130

Query: 122 VQRDLKLVQGFMPHFFRLFRSTVKQVDFSE-VERARFIINDWVKTHTKGMISNLLGKGAV 180
            ++     + ++    + + S  + VDF E  E AR  IN WVKT TKG I NLL +G+V
Sbjct: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190

Query: 181 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD 240
           D  TR+VLVNA+YF G+WKTPF         F  +      V MM    K N        
Sbjct: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNI------- 243

Query: 241 GHYYD----ILELPYHGDTLSMFIAAPYE---KEVPLSALTNILSAQLISHW--KGNMTR 291
           G+  D    ILELPY GD +SMF+  P E       L  L + ++   ++ W  K  M  
Sbjct: 244 GYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAE 302

Query: 292 LPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEV 351
               + +P+F LE   +LR  L ++GM D F + +A+F+ +S++  L +++   +  ++V
Sbjct: 303 DEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDV 362

Query: 352 NESGTVASSSTAVIVSARM--APEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402
           NE GT A++ T  +++ R      + + D PFLF++ H  T  +LF G+   P
Sbjct: 363 NEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 2 [Homo sapiens]
          Length = 415

 Score =  171 bits (432), Expect = 1e-42
 Identities = 120/413 (29%), Positives = 196/413 (47%), Gaps = 56/413 (13%)

Query: 38  FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---------- 87
           F + +F+ +A+AS  +N+  SP+ ++S +AM+ + + G T+ Q+   + F          
Sbjct: 11  FALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGANAVTP 70

Query: 88  ------------KIDDKGMAP--------------ALRHLYKELMGPWNKDEISTTDAIF 121
                       +   KG  P              + R L   +        + + + +F
Sbjct: 71  MTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGNYLLESVNKLF 130

Query: 122 VQRDLKLVQGFMPHFFRLFRSTVKQVDFSE-VERARFIINDWVKTHTKGMISNLLGKGAV 180
            ++     + ++    + + S  + VDF E  E AR  IN WVKT TKG I NLL +G+V
Sbjct: 131 GEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSV 190

Query: 181 DQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPD 240
           D  TR+VLVNA+YF G+WKTPF         F  +      V MM    K N        
Sbjct: 191 DGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREKLNI------- 243

Query: 241 GHYYD----ILELPYHGDTLSMFIAAPYE---KEVPLSALTNILSAQLISHW--KGNMTR 291
           G+  D    ILELPY GD +SMF+  P E       L  L + ++   ++ W  K  M  
Sbjct: 244 GYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDKMAE 302

Query: 292 LPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEV 351
               + +P+F LE   +LR  L ++GM D F + +A+F+ +S++  L +++   +  ++V
Sbjct: 303 DEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAMVDV 362

Query: 352 NESGTVASSSTAVIVSARM--APEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402
           NE GT A++ T  +++ R      + + D PFLF++ H  T  +LF G+   P
Sbjct: 363 NEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  170 bits (430), Expect = 2e-42
 Identities = 109/370 (29%), Positives = 191/370 (51%), Gaps = 12/370 (3%)

Query: 36  SDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGF---KIDDK 92
           ++F   +++Q+A  S   N+ FSP  +A+  AML L T  +T  +I   + F   +I + 
Sbjct: 55  AEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114

Query: 93  GMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEV 152
            +    + L + L  P ++ +++T + +F+   LKLV  F+    +L+ S    V+F + 
Sbjct: 115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDT 174

Query: 153 ERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLF 212
           E A+  IND+V+  T+G I +L+ +  +D+ T   LVN ++F G+W+ PF    T    F
Sbjct: 175 EEAKKQINDYVEKGTQGKIVDLVKE--LDRDTVFALVNYIFFKGKWERPFEVKDTEEEDF 232

Query: 213 HKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSA 272
           H    +TV VPMM +   FN             +L + Y G+  ++F      K   L  
Sbjct: 233 HVDQVTTVKVPMMKRLGMFNIQHCKKLSSW---VLLMKYLGNATAIFFLPDEGK---LQH 286

Query: 273 LTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSL 332
           L N L+  +I+ +  N  R    L LPK S+    DL+  L  LG+T +F    AD + +
Sbjct: 287 LENELTHDIITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSN-GADLSGV 345

Query: 333 SDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGT 392
           +++ PL +++A+ K  + ++E GT A+ +  +       P E+  ++PF+F++    T +
Sbjct: 346 TEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKS 405

Query: 393 VLFMGQVMEP 402
            LFMG+V+ P
Sbjct: 406 PLFMGKVVNP 415


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,034,870
Number of Sequences: 37866
Number of extensions: 562323
Number of successful extensions: 1314
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1059
Number of HSP's gapped (non-prelim): 64
length of query: 402
length of database: 18,247,518
effective HSP length: 105
effective length of query: 297
effective length of database: 14,271,588
effective search space: 4238661636
effective search space used: 4238661636
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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