Guide to the Human Genome
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Search of human proteins with 117306172

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ...   624   e-179
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ...   624   e-179
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa...   624   e-179
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]     252   3e-67
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]          252   3e-67
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]       252   3e-67
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s...   252   3e-67
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]        248   5e-66
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]                     247   1e-65
gi|91823048 kallikrein 14 preproprotein [Homo sapiens]                241   4e-64
gi|11496281 kallikrein 13 precursor [Homo sapiens]                    241   4e-64
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H...   237   1e-62
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho...   237   1e-62
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]             232   3e-61
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote...   220   1e-57
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei...   220   1e-57
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]                    219   2e-57
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           219   3e-57
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot...   218   4e-57
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]                     210   1e-54
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]           204   7e-53
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho...   204   1e-52
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]       204   1e-52
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]        204   1e-52
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]           202   3e-52
gi|4504875 kallikrein 1 preproprotein [Homo sapiens]                  190   1e-48
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo...   185   5e-47
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ...   185   5e-47
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ...   185   5e-47
gi|71834855 prostate specific antigen isoform 4 preproprotein [H...   180   2e-45

>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  624 bits (1608), Expect = e-179
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60
           MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
Sbjct: 1   MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60

Query: 61  DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120
           DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
Sbjct: 61  DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120

Query: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
           YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
Sbjct: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
           AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
           CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293


>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  624 bits (1608), Expect = e-179
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60
           MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
Sbjct: 1   MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60

Query: 61  DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120
           DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
Sbjct: 61  DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120

Query: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
           YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
Sbjct: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
           AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
           CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293


>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
           sapiens]
          Length = 293

 Score =  624 bits (1608), Expect = e-179
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60
           MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS
Sbjct: 1   MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60

Query: 61  DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120
           DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH
Sbjct: 61  DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120

Query: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
           YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS
Sbjct: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
           AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS
Sbjct: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
           CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
Sbjct: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293


>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  252 bits (643), Expect = 3e-67
 Identities = 118/233 (50%), Positives = 160/233 (68%), Gaps = 7/233 (3%)

Query: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
           +RII G +C  H+QPWQAAL  +  +L CGA L+ P+WLLTAAHC K  + V LG ++L 
Sbjct: 20  TRIIKGFECKPHSQPWQAALFEK-TRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78

Query: 125 PVYESGQQMFQGVKSIPHPGYSHP----GHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
              E  +Q     +S PHPG+++      H ND+ML+K+   +  T  VRP+ +SS C +
Sbjct: 79  KE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT 137

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRD 239
           AGT CL+SGWG+T SPQ+  P  L+C NI+++  ++CE+AYP  I DTM CA   + G+D
Sbjct: 138 AGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKD 197

Query: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           SCQGDSGGP+VCN SLQG++SWG  PCA   +PGVYT +CK+  WIQET++ N
Sbjct: 198 SCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250


>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
          Length = 282

 Score =  252 bits (643), Expect = 3e-67
 Identities = 118/233 (50%), Positives = 160/233 (68%), Gaps = 7/233 (3%)

Query: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
           +RII G +C  H+QPWQAAL  +  +L CGA L+ P+WLLTAAHC K  + V LG ++L 
Sbjct: 52  TRIIKGFECKPHSQPWQAALFEK-TRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110

Query: 125 PVYESGQQMFQGVKSIPHPGYSHP----GHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
              E  +Q     +S PHPG+++      H ND+ML+K+   +  T  VRP+ +SS C +
Sbjct: 111 KE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT 169

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRD 239
           AGT CL+SGWG+T SPQ+  P  L+C NI+++  ++CE+AYP  I DTM CA   + G+D
Sbjct: 170 AGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKD 229

Query: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           SCQGDSGGP+VCN SLQG++SWG  PCA   +PGVYT +CK+  WIQET++ N
Sbjct: 230 SCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 282


>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
          Length = 250

 Score =  252 bits (643), Expect = 3e-67
 Identities = 118/233 (50%), Positives = 160/233 (68%), Gaps = 7/233 (3%)

Query: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
           +RII G +C  H+QPWQAAL  +  +L CGA L+ P+WLLTAAHC K  + V LG ++L 
Sbjct: 20  TRIIKGFECKPHSQPWQAALFEK-TRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78

Query: 125 PVYESGQQMFQGVKSIPHPGYSHP----GHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
              E  +Q     +S PHPG+++      H ND+ML+K+   +  T  VRP+ +SS C +
Sbjct: 79  KE-EGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVT 137

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAGRD 239
           AGT CL+SGWG+T SPQ+  P  L+C NI+++  ++CE+AYP  I DTM CA   + G+D
Sbjct: 138 AGTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKD 197

Query: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           SCQGDSGGP+VCN SLQG++SWG  PCA   +PGVYT +CK+  WIQET++ N
Sbjct: 198 SCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQETMKNN 250


>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
           sapiens]
          Length = 254

 Score =  252 bits (643), Expect = 3e-67
 Identities = 132/293 (45%), Positives = 178/293 (60%), Gaps = 40/293 (13%)

Query: 1   MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARS 60
           MATA  PW W L  LI    LGV   +++                               
Sbjct: 1   MATAGNPWGWFLGYLI----LGVAGSLVSG------------------------------ 26

Query: 61  DDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGH 120
             S S+IING DC  H+QPWQAAL++  N+L+C  VLVHPQW+L+AAHC +  + + LG 
Sbjct: 27  --SCSQIINGEDCSPHSQPWQAALVME-NELFCSGVLVHPQWVLSAAHCFQNSYTIGLGL 83

Query: 121 YSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
           +SL    E G QM +   S+ HP Y+ P  +NDLMLIKL+  +  +  +R I+++S CP+
Sbjct: 84  HSLEADQEPGSQMVEASLSVRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPT 143

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCA-GDKAGRD 239
           AG  CLVSGWG   + ++  P VLQC+N+SV+S++ C   Y      +MFCA G    +D
Sbjct: 144 AGNSCLVSGWGLLANGRM--PTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKD 201

Query: 240 SCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           SC GDSGGP++CNG LQGLVS+G  PC +   PGVYTNLCKFT+WI++T+QA+
Sbjct: 202 SCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS 254


>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
          Length = 260

 Score =  248 bits (633), Expect = 5e-66
 Identities = 117/242 (48%), Positives = 158/242 (65%), Gaps = 8/242 (3%)

Query: 51  GAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCR 110
           GA AG     +D   +++ G +C  H+QPWQAA L +  QL CG VLV   W+LTAAHC+
Sbjct: 20  GAWAGHSRAQED---KVLGGHECQPHSQPWQAA-LFQGQQLLCGGVLVGGNWVLTAAHCK 75

Query: 111 KKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSH---PGHSNDLMLIKLNRRIRPTK 167
           K  + VRLG +SL    +  +Q    V+SIPHP Y+      H++DLML++L  +     
Sbjct: 76  KPKYTVRLGDHSLQN-KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGS 134

Query: 168 DVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDD 227
            V+PI+++ HC   G KC VSGWGT  SP+ +FP  L C  + +  QK+CEDAYP QI D
Sbjct: 135 KVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITD 194

Query: 228 TMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287
            M CAG   G D+CQGDSGGP+VC+G+LQG+ SWG  PC R ++PGVYTN+C++  WI++
Sbjct: 195 GMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 254

Query: 288 TI 289
            I
Sbjct: 255 II 256


>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
          Length = 305

 Score =  247 bits (630), Expect = 1e-65
 Identities = 118/255 (46%), Positives = 161/255 (63%), Gaps = 8/255 (3%)

Query: 38  PSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVL 97
           PS+      +  L   AG     +D   +++ G +C  H+QPWQAAL  +  QL CG VL
Sbjct: 52  PSHCPRGWRSNPLPPAAGHSRAQED---KVLGGHECQPHSQPWQAALF-QGQQLLCGGVL 107

Query: 98  VHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPG---HSNDL 154
           V   W+LTAAHC+K  + VRLG +SL    +  +Q    V+SIPHP Y+      H++DL
Sbjct: 108 VGGNWVLTAAHCKKPKYTVRLGDHSLQNK-DGPEQEIPVVQSIPHPCYNSSDVEDHNHDL 166

Query: 155 MLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQ 214
           ML++L  +      V+PI+++ HC   G KC VSGWGT  SP+ +FP  L C  + +  Q
Sbjct: 167 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 226

Query: 215 KRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGV 274
           K+CEDAYP QI D M CAG   G D+CQGDSGGP+VC+G+LQG+ SWG  PC R ++PGV
Sbjct: 227 KKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGV 286

Query: 275 YTNLCKFTKWIQETI 289
           YTN+C++  WI++ I
Sbjct: 287 YTNICRYLDWIKKII 301


>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
          Length = 267

 Score =  241 bits (616), Expect = 4e-64
 Identities = 115/234 (49%), Positives = 155/234 (66%), Gaps = 3/234 (1%)

Query: 59  RSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLY-CGAVLVHPQWLLTAAHCRKKVFRVR 117
           +S +  ++II G  C   +QPWQAALL  P + + CG  L+  QW++TAAHC + + +V 
Sbjct: 33  QSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVA 92

Query: 118 LGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
           LG ++L   +E+ QQ+ + V+ + HP Y+   H NDLML++L +  R  + VRPI V+  
Sbjct: 93  LGKHNLRR-WEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQA 151

Query: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKA 236
           C S GT C VSGWGT  SP   +P  LQC+NI++   + C+ AYPR I   M CAG  + 
Sbjct: 152 CASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMVCAGVPQG 211

Query: 237 GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
           G+DSCQGDSGGP+VC G LQGLVSWG   CA P  PGVYTNLCK+  WI+ET++
Sbjct: 212 GKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMR 265


>gi|11496281 kallikrein 13 precursor [Homo sapiens]
          Length = 277

 Score =  241 bits (616), Expect = 4e-64
 Identities = 117/237 (49%), Positives = 167/237 (70%), Gaps = 8/237 (3%)

Query: 60  SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
           ++ +S  +  G  C  H+QPWQAALL++  +L CG VLVHP+W+LTAAHC K+  +V LG
Sbjct: 29  TNGTSGFLPGGYTCFPHSQPWQAALLVQ-GRLLCGGVLVHPKWVLTAAHCLKEGLKVYLG 87

Query: 120 HYSLSPVYESGQQMFQGVKSIPHPGY----SHPGHSNDLMLIKLNRRIRPTKDVRPINVS 175
            ++L  V E+G+Q+ + V SIPHP Y    +H  H +D+ML++L   ++ T  ++ + +S
Sbjct: 88  KHALGRV-EAGEQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLS 146

Query: 176 -SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD 234
            ++  + GT C VSGWGTT SPQV++PK LQC NI + S + C   YP +I D M CAG 
Sbjct: 147 HNNRLTPGTTCRVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGT 206

Query: 235 K-AGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
           K  G+DSC+GDSGGP+VCN +L G+VSWGD+PC +P+RPGVYT + ++  WI+ETI+
Sbjct: 207 KEGGKDSCEGDSGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIR 263


>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  237 bits (604), Expect = 1e-62
 Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)

Query: 54  AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113
           AGE+A+ D    +II+G+ C   + PWQ A LL  NQL+CG VLV+ +W+LTAAHC+   
Sbjct: 21  AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75

Query: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173
           + V LG  +L    +   Q  +  KS  HPGYS   H NDLML+KLN + R +  V+ + 
Sbjct: 76  YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132

Query: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
           + S C   GT C VSGWGTT SP V FP  L C+++ ++S + C   Y   ++++M CAG
Sbjct: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192

Query: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
              + +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250


>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
           sapiens]
          Length = 253

 Score =  237 bits (604), Expect = 1e-62
 Identities = 114/238 (47%), Positives = 157/238 (65%), Gaps = 9/238 (3%)

Query: 54  AGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKV 113
           AGE+A+ D    +II+G+ C   + PWQ A LL  NQL+CG VLV+ +W+LTAAHC+   
Sbjct: 21  AGEEAQGD----KIIDGAPCARGSHPWQVA-LLSGNQLHCGGVLVNERWVLTAAHCKMNE 75

Query: 114 FRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN 173
           + V LG  +L    +   Q  +  KS  HPGYS   H NDLML+KLN + R +  V+ + 
Sbjct: 76  YTVHLGSDTLG---DRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVR 132

Query: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
           + S C   GT C VSGWGTT SP V FP  L C+++ ++S + C   Y   ++++M CAG
Sbjct: 133 LPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAG 192

Query: 234 -DKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
              + +++C GDSGGP+VC G+LQGLVSWG +PC +PN PGVYT +CKFTKWI +T++
Sbjct: 193 IPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 250


>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
          Length = 250

 Score =  232 bits (592), Expect = 3e-61
 Identities = 114/233 (48%), Positives = 153/233 (65%), Gaps = 7/233 (3%)

Query: 63  SSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYS 122
           + +R I   +C  ++QPWQA L     +L+CGA L+  +WLLTAAHCRK    VRLG + 
Sbjct: 19  ADTRAIGAEECRPNSQPWQAGLF-HLTRLFCGATLISDRWLLTAAHCRKPYLWVRLGEHH 77

Query: 123 LSPVYESGQQMFQGVKSIPHPGY----SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHC 178
           L   +E  +Q+F+     PHPG+    S   H++D+MLI+L R+ R +  V+P+N+S  C
Sbjct: 78  LWK-WEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNLSQTC 136

Query: 179 PSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG-DKAG 237
            S G +CL+SGWG   SP+  FP  LQC NIS+L  K C  AYP  I D+M CAG  + G
Sbjct: 137 VSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGLWEGG 196

Query: 238 RDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQ 290
           R SCQGDSGGP+VCNG+L G+VS G  PC+RP RP VYT++C +  WIQE ++
Sbjct: 197 RGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIME 249


>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  220 bits (560), Expect = 1e-57
 Identities = 104/231 (45%), Positives = 148/231 (64%), Gaps = 5/231 (2%)

Query: 62  DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
           +  +++++G  CD  + P+QAAL      L CG VL+HP W+LTAAHC+K   +V LG +
Sbjct: 17  EEQNKLVHGGPCDKTSHPYQAALYTS-GHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKH 75

Query: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
           +L    ES Q+    V+++ HP Y    H  D+ML++L R  + ++ ++P+ +   C + 
Sbjct: 76  NLRQ-RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134

Query: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
            T C + GWG T      FP  +QC  I ++S++ CE AYP QI   M CAGD K G+DS
Sbjct: 135 TTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
           CQGDSGGP+VC   L+GLVSWG+ PC    +PGVYTN+C++T WIQ+TIQA
Sbjct: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243


>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
           [Homo sapiens]
          Length = 244

 Score =  220 bits (560), Expect = 1e-57
 Identities = 104/231 (45%), Positives = 148/231 (64%), Gaps = 5/231 (2%)

Query: 62  DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
           +  +++++G  CD  + P+QAAL      L CG VL+HP W+LTAAHC+K   +V LG +
Sbjct: 17  EEQNKLVHGGPCDKTSHPYQAALYTS-GHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKH 75

Query: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
           +L    ES Q+    V+++ HP Y    H  D+ML++L R  + ++ ++P+ +   C + 
Sbjct: 76  NLRQ-RESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134

Query: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
            T C + GWG T      FP  +QC  I ++S++ CE AYP QI   M CAGD K G+DS
Sbjct: 135 TTSCHILGWGKTADGD--FPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQA 291
           CQGDSGGP+VC   L+GLVSWG+ PC    +PGVYTN+C++T WIQ+TIQA
Sbjct: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQA 243


>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
          Length = 248

 Score =  219 bits (558), Expect = 2e-57
 Identities = 107/236 (45%), Positives = 148/236 (62%), Gaps = 5/236 (2%)

Query: 60  SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
           S  ++ +I NG++C  ++QPWQ  L      L CG VL+  +W+LTAAHC    + VRLG
Sbjct: 15  SQAATPKIFNGTECGRNSQPWQVGLF-EGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLG 73

Query: 120 HYSLSPVYESGQQMFQGVKSIPHPGY--SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
            +SLS +  + Q    G  S+ HPGY  +   H +DL L++L   +R T  V+P+ + + 
Sbjct: 74  EHSLSQLDWTEQIRHSGF-SVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPND 132

Query: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAG 237
           C +AGT+C VSGWG T  P+  FP +LQCLN+S++S   C   YP +I   M CAG   G
Sbjct: 133 CATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPG 192

Query: 238 RDSCQGDSGGPVVCNGSLQGLVSWGDY-PCARPNRPGVYTNLCKFTKWIQETIQAN 292
           +D+CQGDSGGP+VC G LQGLVSWG   PC +   PGVYT +CK+  WI+  ++ N
Sbjct: 193 QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIMRNN 248


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  219 bits (557), Expect = 3e-57
 Identities = 108/233 (46%), Positives = 148/233 (63%), Gaps = 5/233 (2%)

Query: 62  DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
           D   +I+ G +C+ ++ P+Q +L       +CG  L++ QW+++A HC K   +VRLG +
Sbjct: 19  DDDDKIVGGYNCEENSVPYQVSL--NSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEH 76

Query: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
           ++  V E  +Q     K I HP Y     +ND+MLIKL+ R      V  I++ +  P+ 
Sbjct: 77  NIE-VLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPAT 135

Query: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
           GTKCL+SGWG T S    +P  LQCL+  VLSQ +CE +YP +I   MFC G  + G+DS
Sbjct: 136 GTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDS 195

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
           CQGDSGGPVVCNG LQG+VSWGD  CA+ N+PGVYT +  + KWI+ TI ANS
Sbjct: 196 CQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAANS 247


>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
           [Homo sapiens]
          Length = 256

 Score =  218 bits (556), Expect = 4e-57
 Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 13/238 (5%)

Query: 66  RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSP 125
           +++ G +C  H+QPWQ AL  R  +  CGA L+ P W+L+AAHC+ +  RVRLG ++L  
Sbjct: 21  KLLEGDECAPHSQPWQVALYER-GRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRK 79

Query: 126 VYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKC 185
             +  +Q+    + IPHP Y    H ND+ML++L +  R    VRP  + + CP  G  C
Sbjct: 80  -RDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEAC 138

Query: 186 LVSGWG--------TTKSP--QVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDK 235
           +VSGWG        T  SP  QV  P  L C NIS++S   C+ +YP ++ +TM CAG +
Sbjct: 139 VVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAE 198

Query: 236 A-GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
             G +SC+GDSGGP+VC G LQG+VSWGD PC    +PGVYT +C + +WI+ET++ N
Sbjct: 199 GRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256


>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
          Length = 254

 Score =  210 bits (535), Expect = 1e-54
 Identities = 104/226 (46%), Positives = 141/226 (62%), Gaps = 5/226 (2%)

Query: 60  SDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLG 119
           S  ++ +I NG++C  ++QPWQ  L      L CG VL+  +W+LTAAHC    + VRLG
Sbjct: 15  SQAATPKIFNGTECGRNSQPWQVGLF-EGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRLG 73

Query: 120 HYSLSPVYESGQQMFQGVKSIPHPGY--SHPGHSNDLMLIKLNRRIRPTKDVRPINVSSH 177
            +SLS +  + Q    G  S+ HPGY  +   H +DL L++L   +R T  V+P+ + + 
Sbjct: 74  EHSLSQLDWTEQIRHSGF-SVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPND 132

Query: 178 CPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAG 237
           C +AGT+C VSGWG T  P+  FP +LQCLN+S++S   C   YP +I   M CAG   G
Sbjct: 133 CATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVPG 192

Query: 238 RDSCQGDSGGPVVCNGSLQGLVSWGDY-PCARPNRPGVYTNLCKFT 282
           +D+CQGDSGGP+VC G LQGLVSWG   PC +   PGVYT +C  T
Sbjct: 193 QDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICNST 238


>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  204 bits (519), Expect = 7e-53
 Identities = 104/233 (44%), Positives = 144/233 (61%), Gaps = 5/233 (2%)

Query: 62  DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
           D   +I+ G  C+ ++ P+Q +L       +CG  L+  QW+++A HC K   +VRLG +
Sbjct: 19  DDDDKIVGGYICEENSVPYQVSL--NSGYHFCGGSLISEQWVVSAGHCYKSRIQVRLGEH 76

Query: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
           ++  V E  +Q     K I HP Y+     ND++LIKL+        V  I++ +  P+A
Sbjct: 77  NIE-VLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPPAA 135

Query: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
           GT+ L+SGWG T S    +P  LQCL+  VLSQ  CE +YP +I + MFC G  + G+DS
Sbjct: 136 GTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDS 195

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
           CQGDSGGPVV NG LQG+VSWG Y CA+ NRPGVYT +  +  WI++TI ANS
Sbjct: 196 CQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGVYTKVYNYVDWIKDTIAANS 247


>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
           sapiens]
          Length = 261

 Score =  204 bits (518), Expect = 1e-52
 Identities = 103/240 (42%), Positives = 146/240 (60%), Gaps = 14/240 (5%)

Query: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
           SRI+ G +C+ H+QPWQ  +  R  +  CG VLVHPQW+LTAAHC +    + LG +SL 
Sbjct: 23  SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLF 81

Query: 125 PVYESGQQMFQGVKSIPHPGYS---------HPGH--SNDLMLIKLNRRIRPTKDVRPIN 173
              ++GQ +FQ   S PHP Y           PG   S+DLML++L+     T  V+ ++
Sbjct: 82  HPEDTGQ-VFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140

Query: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
           + +  P+ GT C  SGWG+ +  +   PK LQC+++ V+S   C   +P+++   M CAG
Sbjct: 141 LPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAG 200

Query: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
               G+ +C GDSGGP+VCNG LQG+ SWG  PCA P RP +YT +  + KWI++TI AN
Sbjct: 201 RWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 260


>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
          Length = 304

 Score =  204 bits (518), Expect = 1e-52
 Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)

Query: 62  DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
           D   +I+ G  C+ ++ P+Q +L       +CG  L+  QW+++AAHC K   +VRLG +
Sbjct: 76  DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 133

Query: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
           ++  V E  +Q     K I HP Y+     ND+MLIKL+        V  I++ +  P+A
Sbjct: 134 NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 192

Query: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
           GT+CL+SGWG T S    +P  L+CL+  VL+Q  C+ +YP +I ++MFC G  + G+DS
Sbjct: 193 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 252

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
           CQ DSGGPVVCNG LQG+VSWG + CA  NRPGVYT +  +  WI++TI ANS
Sbjct: 253 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 304


>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  204 bits (518), Expect = 1e-52
 Identities = 103/233 (44%), Positives = 146/233 (62%), Gaps = 5/233 (2%)

Query: 62  DSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHY 121
           D   +I+ G  C+ ++ P+Q +L       +CG  L+  QW+++AAHC K   +VRLG +
Sbjct: 19  DDDDKIVGGYTCEENSLPYQVSL--NSGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEH 76

Query: 122 SLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSA 181
           ++  V E  +Q     K I HP Y+     ND+MLIKL+        V  I++ +  P+A
Sbjct: 77  NIK-VLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAA 135

Query: 182 GTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDS 240
           GT+CL+SGWG T S    +P  L+CL+  VL+Q  C+ +YP +I ++MFC G  + G+DS
Sbjct: 136 GTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDS 195

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 293
           CQ DSGGPVVCNG LQG+VSWG + CA  NRPGVYT +  +  WI++TI ANS
Sbjct: 196 CQRDSGGPVVCNGQLQGVVSWG-HGCAWKNRPGVYTKVYNYVDWIKDTIAANS 247


>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
          Length = 261

 Score =  202 bits (514), Expect = 3e-52
 Identities = 102/240 (42%), Positives = 147/240 (61%), Gaps = 14/240 (5%)

Query: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
           SRI+ G +C+ H+QPWQ A+       +CG VLVHPQW+LTAAHC KK  +V LG ++L 
Sbjct: 23  SRIVGGWECEKHSQPWQVAVYSH-GWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81

Query: 125 PVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIKLNRRIRPTKDVRPIN 173
              ++GQ++     S PHP Y+               S+DLML++L+   + T  V+ + 
Sbjct: 82  EPEDTGQRVPVS-HSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLG 140

Query: 174 VSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAG 233
           + +  P+ GT C  SGWG+ +  +   P+ LQC+++ +LS   C  AY  ++ + M CAG
Sbjct: 141 LPTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAG 200

Query: 234 D-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
               G+D+C GDSGGP+VCNG LQG+ SWG  PCA P +P VYT +  + KWI++TI AN
Sbjct: 201 LWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260


>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
          Length = 262

 Score =  190 bits (483), Expect = 1e-48
 Identities = 96/257 (37%), Positives = 145/257 (56%), Gaps = 15/257 (5%)

Query: 50  LGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHC 109
           L    G    +    SRI+ G +C+ H+QPWQAAL    +   CG +LVH QW+LTAAHC
Sbjct: 8   LALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALY-HFSTFQCGGILVHRQWVLTAAHC 66

Query: 110 RKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYS-----------HPGHSNDLMLIK 158
               +++ LG ++L    E+  Q     +S PHPG++              +S+DLML++
Sbjct: 67  ISDNYQLWLGRHNLFDD-ENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLR 125

Query: 159 LNRRIRPTKD-VRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRC 217
           L        D V+ + + +  P  G+ CL SGWG+ +     FP  LQC+++ +L    C
Sbjct: 126 LTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDEC 185

Query: 218 EDAYPRQIDDTMFCAGD-KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYT 276
           + A+ +++ D M C G  + G+D+C GDSGGP++C+G LQG+ SWG  PC  PN+P V  
Sbjct: 186 KKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAV 245

Query: 277 NLCKFTKWIQETIQANS 293
            +  + KWI++TI  NS
Sbjct: 246 RVLSYVKWIEDTIAENS 262


>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  185 bits (469), Expect = 5e-47
 Identities = 95/232 (40%), Positives = 132/232 (56%), Gaps = 13/232 (5%)

Query: 70  GSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYES 129
           GS C   +QPWQ +L       +C  VLV   W+LTAAHC  K    R+G   L  +   
Sbjct: 49  GSPCARGSQPWQVSLF-NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHL--LLLQ 105

Query: 130 GQQMFQGVKSIPHPGYSHPGHS---------NDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
           G+Q+ +  +S+ HP Y H G           +DLML+KL R +     VR + +   C  
Sbjct: 106 GEQLRRTTRSVVHPKY-HQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 164

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
            G +C V+GWGTT + +V + K L C +I++LS K CE  YP  + + M CAG   G+D 
Sbjct: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDP 224

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           CQ DSGGP+VC+ +LQG++SWG YPC     P VYT +CK+  WI + I++N
Sbjct: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276


>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  185 bits (469), Expect = 5e-47
 Identities = 95/232 (40%), Positives = 132/232 (56%), Gaps = 13/232 (5%)

Query: 70  GSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYES 129
           GS C   +QPWQ +L       +C  VLV   W+LTAAHC  K    R+G   L  +   
Sbjct: 49  GSPCARGSQPWQVSLF-NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHL--LLLQ 105

Query: 130 GQQMFQGVKSIPHPGYSHPGHS---------NDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
           G+Q+ +  +S+ HP Y H G           +DLML+KL R +     VR + +   C  
Sbjct: 106 GEQLRRTTRSVVHPKY-HQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 164

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
            G +C V+GWGTT + +V + K L C +I++LS K CE  YP  + + M CAG   G+D 
Sbjct: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDP 224

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           CQ DSGGP+VC+ +LQG++SWG YPC     P VYT +CK+  WI + I++N
Sbjct: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276


>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
           sapiens]
          Length = 276

 Score =  185 bits (469), Expect = 5e-47
 Identities = 95/232 (40%), Positives = 132/232 (56%), Gaps = 13/232 (5%)

Query: 70  GSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYES 129
           GS C   +QPWQ +L       +C  VLV   W+LTAAHC  K    R+G   L  +   
Sbjct: 49  GSPCARGSQPWQVSLF-NGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHL--LLLQ 105

Query: 130 GQQMFQGVKSIPHPGYSHPGHS---------NDLMLIKLNRRIRPTKDVRPINVSSHCPS 180
           G+Q+ +  +S+ HP Y H G           +DLML+KL R +     VR + +   C  
Sbjct: 106 GEQLRRTTRSVVHPKY-HQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 164

Query: 181 AGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDS 240
            G +C V+GWGTT + +V + K L C +I++LS K CE  YP  + + M CAG   G+D 
Sbjct: 165 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDP 224

Query: 241 CQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           CQ DSGGP+VC+ +LQG++SWG YPC     P VYT +CK+  WI + I++N
Sbjct: 225 CQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276


>gi|71834855 prostate specific antigen isoform 4 preproprotein [Homo
           sapiens]
          Length = 218

 Score =  180 bits (456), Expect = 2e-45
 Identities = 91/229 (39%), Positives = 129/229 (56%), Gaps = 35/229 (15%)

Query: 65  SRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLS 124
           SRI+ G +C+ H+QPWQ  +  R  +  CG VLVHPQW+LTAAHC +K            
Sbjct: 23  SRIVGGWECEKHSQPWQVLVASR-GRAVCGGVLVHPQWVLTAAHCIRK------------ 69

Query: 125 PVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTK 184
                             PG      S+DLML++L+     T  V+ +++ +  P+ GT 
Sbjct: 70  ------------------PG---DDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTT 108

Query: 185 CLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD-KAGRDSCQG 243
           C  SGWG+ +  +   PK LQC+++ V+S   C   +P+++   M CAG    G+ +C G
Sbjct: 109 CYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSG 168

Query: 244 DSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
           DSGGP+VCNG LQG+ SWG  PCA P RP +YT +  + KWI++TI AN
Sbjct: 169 DSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 217


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,096,918
Number of Sequences: 37866
Number of extensions: 620015
Number of successful extensions: 2045
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1319
Number of HSP's gapped (non-prelim): 224
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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