Guide to the Human Genome
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Search of human proteins with 117190324

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|117190324 diphthine synthase isoform b [Homo sapiens]
         (284 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|117190324 diphthine synthase isoform b [Homo sapiens]              563   e-161
gi|117190326 diphthine synthase isoform a [Homo sapiens]              558   e-159
gi|117190262 diphthine synthase isoform a [Homo sapiens]              558   e-159
gi|38504671 secernin 3 [Homo sapiens]                                  31   1.1  
gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]          31   1.4  
gi|226874833 guanylate kinase 1 isoform b [Homo sapiens]               31   1.4  
gi|226874831 guanylate kinase 1 isoform a [Homo sapiens]               31   1.4  
gi|4504221 guanylate kinase 1 isoform b [Homo sapiens]                 31   1.4  
gi|194097432 hypothetical protein LOC285966 B [Homo sapiens]           30   2.4  
gi|194097428 hypothetical protein LOC285966 A [Homo sapiens]           30   2.4  
gi|194097425 hypothetical protein LOC285966 A [Homo sapiens]           30   2.4  
gi|62953116 BTB (POZ) domain containing 11 isoform b [Homo sapiens]    28   9.1  
gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]    28   9.1  

>gi|117190324 diphthine synthase isoform b [Homo sapiens]
          Length = 284

 Score =  563 bits (1450), Expect = e-161
 Identities = 284/284 (100%), Positives = 284/284 (100%)

Query: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60
           MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
Sbjct: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60

Query: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120
           VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
Sbjct: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120

Query: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180
           GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
Sbjct: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180

Query: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPVTEETLCVGLARVGADDQKIAAGTLRQMC 240
           IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPVTEETLCVGLARVGADDQKIAAGTLRQMC
Sbjct: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPVTEETLCVGLARVGADDQKIAAGTLRQMC 240

Query: 241 TVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 284
           TVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
Sbjct: 241 TVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 284


>gi|117190326 diphthine synthase isoform a [Homo sapiens]
          Length = 285

 Score =  558 bits (1438), Expect = e-159
 Identities = 284/285 (99%), Positives = 284/285 (99%), Gaps = 1/285 (0%)

Query: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60
           MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
Sbjct: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60

Query: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120
           VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
Sbjct: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120

Query: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180
           GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
Sbjct: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180

Query: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEP-VTEETLCVGLARVGADDQKIAAGTLRQM 239
           IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEP VTEETLCVGLARVGADDQKIAAGTLRQM
Sbjct: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM 240

Query: 240 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 284
           CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
Sbjct: 241 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 285


>gi|117190262 diphthine synthase isoform a [Homo sapiens]
          Length = 285

 Score =  558 bits (1438), Expect = e-159
 Identities = 284/285 (99%), Positives = 284/285 (99%), Gaps = 1/285 (0%)

Query: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60
           MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE
Sbjct: 1   MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREE 60

Query: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120
           VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC
Sbjct: 61  VEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCC 120

Query: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180
           GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK
Sbjct: 121 GLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRK 180

Query: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEP-VTEETLCVGLARVGADDQKIAAGTLRQM 239
           IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEP VTEETLCVGLARVGADDQKIAAGTLRQM
Sbjct: 181 IYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQM 240

Query: 240 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 284
           CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
Sbjct: 241 CTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL 285


>gi|38504671 secernin 3 [Homo sapiens]
          Length = 424

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 17/46 (36%), Positives = 24/46 (52%)

Query: 158 HTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQN 203
           H   LLD       LE+L+K +  ++P R   + Q  QQ LE+V N
Sbjct: 317 HISQLLDTSSPTFELEDLVKKKSHFKPDRRHPLYQKHQQALEVVNN 362


>gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]
          Length = 501

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 16/86 (18%)

Query: 166 KVKEQSLENLIKG--RKI------YEPPRYMSVNQAAQ----QLLEIVQNQRIRGEEPVT 213
           +V+E   EN  K   RKI      ++ P +  ++QAA+    +L+E+ Q+QRI  EE ++
Sbjct: 223 EVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAIS 282

Query: 214 EETLCVGLARVGADDQKIAAGTLRQM 239
            E     ++   A D+ I  G   Q+
Sbjct: 283 HE----WISGNAASDKNIKDGVCAQI 304


>gi|226874833 guanylate kinase 1 isoform b [Homo sapiens]
          Length = 197

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 9/80 (11%)

Query: 148 KVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIR 207
           KV       M+ +C+LD+ +  Q + N IK   +   P Y+SV   +  +LE    QR+R
Sbjct: 85  KVAVQAVQAMNRICVLDVDL--QGVRN-IKATDLR--PIYISVQPPSLHVLE----QRLR 135

Query: 208 GEEPVTEETLCVGLARVGAD 227
                TEE+L   LA   AD
Sbjct: 136 QRNTETEESLVKRLAAAQAD 155


>gi|226874831 guanylate kinase 1 isoform a [Homo sapiens]
          Length = 218

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 9/80 (11%)

Query: 148 KVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIR 207
           KV       M+ +C+LD+ +  Q + N IK   +   P Y+SV   +  +LE    QR+R
Sbjct: 106 KVAVQAVQAMNRICVLDVDL--QGVRN-IKATDLR--PIYISVQPPSLHVLE----QRLR 156

Query: 208 GEEPVTEETLCVGLARVGAD 227
                TEE+L   LA   AD
Sbjct: 157 QRNTETEESLVKRLAAAQAD 176


>gi|4504221 guanylate kinase 1 isoform b [Homo sapiens]
          Length = 197

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 27/80 (33%), Positives = 39/80 (48%), Gaps = 9/80 (11%)

Query: 148 KVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIR 207
           KV       M+ +C+LD+ +  Q + N IK   +   P Y+SV   +  +LE    QR+R
Sbjct: 85  KVAVQAVQAMNRICVLDVDL--QGVRN-IKATDLR--PIYISVQPPSLHVLE----QRLR 135

Query: 208 GEEPVTEETLCVGLARVGAD 227
                TEE+L   LA   AD
Sbjct: 136 QRNTETEESLVKRLAAAQAD 155


>gi|194097432 hypothetical protein LOC285966 B [Homo sapiens]
          Length = 564

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 185 PRYMSVNQAAQQLLEIVQNQRIRGEEPVTEET-------LCVGLARVGADDQKIAAGTLR 237
           P Y+S+++  +++L       +  E PV  ++       L  GLA  G D  ++A G   
Sbjct: 175 PAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGT 234

Query: 238 QMCTVDLGEPLHSLIITGGSIHP 260
             C+  L    H + +    I+P
Sbjct: 235 WTCSSSLYPSKHPITVEINGINP 257


>gi|194097428 hypothetical protein LOC285966 A [Homo sapiens]
          Length = 845

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 185 PRYMSVNQAAQQLLEIVQNQRIRGEEPVTEET-------LCVGLARVGADDQKIAAGTLR 237
           P Y+S+++  +++L       +  E PV  ++       L  GLA  G D  ++A G   
Sbjct: 456 PAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGT 515

Query: 238 QMCTVDLGEPLHSLIITGGSIHP 260
             C+  L    H + +    I+P
Sbjct: 516 WTCSSSLYPSKHPITVEINGINP 538


>gi|194097425 hypothetical protein LOC285966 A [Homo sapiens]
          Length = 845

 Score = 30.0 bits (66), Expect = 2.4
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 7/83 (8%)

Query: 185 PRYMSVNQAAQQLLEIVQNQRIRGEEPVTEET-------LCVGLARVGADDQKIAAGTLR 237
           P Y+S+++  +++L       +  E PV  ++       L  GLA  G D  ++A G   
Sbjct: 456 PAYISLHRLLRKMLRGSGLPAVSRENPVASDSYEAAVLSLATGLAHSGTDCSQLAQGLGT 515

Query: 238 QMCTVDLGEPLHSLIITGGSIHP 260
             C+  L    H + +    I+P
Sbjct: 516 WTCSSSLYPSKHPITVEINGINP 538


>gi|62953116 BTB (POZ) domain containing 11 isoform b [Homo sapiens]
          Length = 641

 Score = 28.1 bits (61), Expect = 9.1
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 52  KLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRAT 99
           KL    R++  +   + L + ++SDV FLV G PF A  H  L+  A+
Sbjct: 437 KLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYA--HKVLLFTAS 482


>gi|65786661 BTB (POZ) domain containing 11 isoform a [Homo sapiens]
          Length = 1104

 Score = 28.1 bits (61), Expect = 9.1
 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 52  KLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRAT 99
           KL    R++  +   + L + ++SDV FLV G PF A  H  L+  A+
Sbjct: 900 KLTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRPFYA--HKVLLFTAS 945


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,812,554
Number of Sequences: 37866
Number of extensions: 397235
Number of successful extensions: 884
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 876
Number of HSP's gapped (non-prelim): 15
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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