Guide to the Human Genome
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Search of human proteins with 116812630

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116812630 short chain dehydrogenase/reductase family 39U,
member 1 [Homo sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116812630 short chain dehydrogenase/reductase family 39U, mem...   587   e-168
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]             37   0.021
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       30   1.9  
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       30   1.9  
gi|161019170 mucin 5AC [Homo sapiens]                                  29   5.6  
gi|239750685 PREDICTED: hypothetical protein XP_002347506 [Homo ...    29   5.6  
gi|239744995 PREDICTED: hypothetical protein XP_002343325 [Homo ...    29   5.6  
gi|19923817 peroxisomal trans-2-enoyl-CoA reductase [Homo sapiens]     29   5.6  
gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]       29   5.6  
gi|34101290 Fas apoptotic inhibitory molecule 2 [Homo sapiens]         29   5.6  
gi|40254992 carbonic reductase 4 [Homo sapiens]                        29   5.6  
gi|28557800 UDP glycosyltransferase 3 family, polypeptide A2 [Ho...    28   7.3  
gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precurs...    28   9.6  
gi|46249416 leukocyte receptor tyrosine kinase isoform 2 precurs...    28   9.6  

>gi|116812630 short chain dehydrogenase/reductase family 39U, member
           1 [Homo sapiens]
          Length = 293

 Score =  587 bits (1513), Expect = e-168
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAG 60
           MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAG
Sbjct: 1   MRVLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAVNLAG 60

Query: 61  ENILNPLRRWNETFQKEVIGSRLETTQLLAKAITKAPQPPKAWVLVTGVAYYQPSLTAEY 120
           ENILNPLRRWNETFQKEVIGSRLETTQLLAKAITKAPQPPKAWVLVTGVAYYQPSLTAEY
Sbjct: 61  ENILNPLRRWNETFQKEVIGSRLETTQLLAKAITKAPQPPKAWVLVTGVAYYQPSLTAEY 120

Query: 121 DEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPFRLGLG 180
           DEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPFRLGLG
Sbjct: 121 DEDSPGGDFDFFSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGGGAMGHMLLPFRLGLG 180

Query: 181 GPIGSGHQFFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALGRRA 240
           GPIGSGHQFFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALGRRA
Sbjct: 181 GPIGSGHQFFPWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALGRRA 240

Query: 241 FIPLPSAVVQAVFGRQRAIMLLEGQKVIPQRTLATGYQYSFPELGAALKEIVA 293
           FIPLPSAVVQAVFGRQRAIMLLEGQKVIPQRTLATGYQYSFPELGAALKEIVA
Sbjct: 241 FIPLPSAVVQAVFGRQRAIMLLEGQKVIPQRTLATGYQYSFPELGAALKEIVA 293


>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
          Length = 420

 Score = 37.0 bits (84), Expect = 0.021
 Identities = 16/29 (55%), Positives = 21/29 (72%)

Query: 2   RVLVGGGTGFIGTALTQLLNARGHEVTLV 30
           R+L+ GG GF+G+ LT  L   GHEVT+V
Sbjct: 90  RILITGGAGFVGSHLTDKLMMDGHEVTVV 118


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 13/107 (12%)

Query: 141 AAARLPGDSTRQVV---------VRSGVVLGRGGGAMGHMLLPFRL-GLGGPIGSGHQFF 190
           A A LPG    Q V         +  G+ L +        L  F+L  L G + +G   +
Sbjct: 86  AMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGD--Y 143

Query: 191 PWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALG 237
             IH G L+G+ T A++   + G +  V   S    + A+ LGAA G
Sbjct: 144 VLIHAG-LSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 30.4 bits (67), Expect = 1.9
 Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 13/107 (12%)

Query: 141 AAARLPGDSTRQVV---------VRSGVVLGRGGGAMGHMLLPFRL-GLGGPIGSGHQFF 190
           A A LPG    Q V         +  G+ L +        L  F+L  L G + +G   +
Sbjct: 86  AMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGD--Y 143

Query: 191 PWIHIGDLAGILTHALEANHVHGVLNGVAPSSATNAEFAQTLGAALG 237
             IH G L+G+ T A++   + G +  V   S    + A+ LGAA G
Sbjct: 144 VLIHAG-LSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAG 189


>gi|161019170 mucin 5AC [Homo sapiens]
          Length = 6207

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 17/94 (18%)

Query: 81   SRLETTQLLAKAITKAP---------QPPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDF 131
            S+  T+ LL  + T AP         +P  AW      +Y  P  +        GGDFD 
Sbjct: 4576 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS--------GGDFDT 4627

Query: 132  FSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGG 165
            +SN+     A    P     +   + GV LG  G
Sbjct: 4628 YSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELG 4661


>gi|239750685 PREDICTED: hypothetical protein XP_002347506 [Homo
           sapiens]
          Length = 684

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 158 GVVLGRGGGAMGHMLLPFRLGLGG-PIGSGHQFFPWIHIGDLAGILTHALEANHVHGV-L 215
           G+++GRG G +  + L  R+ + G P+      +PW+ +  + G+      A H  G+ L
Sbjct: 457 GLIMGRGAGKVSPLGLRARVKIAGTPVS-----WPWLALAHVVGVGLMVDGAEHQAGLGL 511

Query: 216 NGVAP 220
            G AP
Sbjct: 512 RGGAP 516


>gi|239744995 PREDICTED: hypothetical protein XP_002343325 [Homo
           sapiens]
          Length = 909

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 158 GVVLGRGGGAMGHMLLPFRLGLGG-PIGSGHQFFPWIHIGDLAGILTHALEANHVHGV-L 215
           G+++GRG G +  + L  R+ + G P+      +PW+ +  + G+      A H  G+ L
Sbjct: 457 GLIMGRGAGKVSPLGLRARVKIAGTPVS-----WPWLALAHVVGVGLMVDGAEHQAGLGL 511

Query: 216 NGVAP 220
            G AP
Sbjct: 512 RGGAP 516


>gi|19923817 peroxisomal trans-2-enoyl-CoA reductase [Homo
          sapiens]
          Length = 303

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 24/70 (34%), Positives = 34/70 (48%), Gaps = 6/70 (8%)

Query: 3  VLVGGGTGFIGTALTQLLNARGHEVTLVSRKPGPGRITWDELAASGLPSCDAAV-----N 57
          ++ GG TG IG A+ + L   G  V + SRK    +   DEL A+  P+  A V     N
Sbjct: 22 IVTGGATG-IGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCN 80

Query: 58 LAGENILNPL 67
          +  E  +N L
Sbjct: 81 IRNEEEVNNL 90


>gi|153945878 mucin 5, subtype B, tracheobronchial [Homo sapiens]
          Length = 5765

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 26/94 (27%), Positives = 36/94 (38%), Gaps = 17/94 (18%)

Query: 81   SRLETTQLLAKAITKAP---------QPPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDF 131
            S+  T+ LL  + T AP         +P  AW      +Y  P  +        GGDFD 
Sbjct: 4106 SKTRTSTLLPSSPTSAPITTVVTTGCEPQCAWSEWLDYSYPMPGPS--------GGDFDT 4157

Query: 132  FSNLVTKWEAAARLPGDSTRQVVVRSGVVLGRGG 165
            +SN+     A    P     +   + GV LG  G
Sbjct: 4158 YSNIRAAGGAVCEQPLGLECRAQAQPGVPLGELG 4191


>gi|34101290 Fas apoptotic inhibitory molecule 2 [Homo sapiens]
          Length = 316

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 14/37 (37%), Positives = 18/37 (48%)

Query: 97  PQPPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDFFS 133
           P  P A  L    AY  PS ++ YD   P GD + F+
Sbjct: 53  PPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFT 89


>gi|40254992 carbonic reductase 4 [Homo sapiens]
          Length = 237

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 21/70 (30%), Positives = 33/70 (47%), Gaps = 9/70 (12%)

Query: 5  VGGGTGFIGTALTQLLNARGHEVTLVSR-----KPGPGRITWDELAASGLPSCDAAVNLA 59
          V GG+  IG A+ QL+  +G+ + +++R     K   G +  D LA     SCD A    
Sbjct: 7  VFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAF----SCDVAKEHD 62

Query: 60 GENILNPLRR 69
           +N    L +
Sbjct: 63 VQNTFEELEK 72


>gi|28557800 UDP glycosyltransferase 3 family, polypeptide A2
          [Homo sapiens]
          Length = 523

 Score = 28.5 bits (62), Expect = 7.3
 Identities = 12/32 (37%), Positives = 19/32 (59%)

Query: 5  VGGGTGFIGTALTQLLNARGHEVTLVSRKPGP 36
          VGG    +   ++Q+L   GH VT+++ K GP
Sbjct: 31 VGGSHYLLMDRVSQILQDHGHNVTMLNHKRGP 62


>gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precursor
           [Homo sapiens]
          Length = 864

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 20/136 (14%)

Query: 32  RKPGPGRITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVIGSRLETTQLLAK 91
           + PGP  +    +A S L    + + + G  IL   ++W    +  +    LE ++L   
Sbjct: 420 KPPGPLVLMVAVVATSTL----SLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTS 475

Query: 92  AITKAPQ---------PPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDFFSNLVTKWEAA 142
           AI  AP          P ++W L  GV    P+          G   + +  LV      
Sbjct: 476 AIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLV------ 529

Query: 143 ARLPGDST-RQVVVRS 157
             LPGDS+  QV +++
Sbjct: 530 IGLPGDSSPLQVAIKT 545


>gi|46249416 leukocyte receptor tyrosine kinase isoform 2 precursor
           [Homo sapiens]
          Length = 803

 Score = 28.1 bits (61), Expect = 9.6
 Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 20/136 (14%)

Query: 32  RKPGPGRITWDELAASGLPSCDAAVNLAGENILNPLRRWNETFQKEVIGSRLETTQLLAK 91
           + PGP  +    +A S L    + + + G  IL   ++W    +  +    LE ++L   
Sbjct: 359 KPPGPLVLMVAVVATSTL----SLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTS 414

Query: 92  AITKAPQ---------PPKAWVLVTGVAYYQPSLTAEYDEDSPGGDFDFFSNLVTKWEAA 142
           AI  AP          P ++W L  GV    P+          G   + +  LV      
Sbjct: 415 AIRTAPNPYYCQVGLGPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLV------ 468

Query: 143 ARLPGDST-RQVVVRS 157
             LPGDS+  QV +++
Sbjct: 469 IGLPGDSSPLQVAIKT 484


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,889,697
Number of Sequences: 37866
Number of extensions: 562279
Number of successful extensions: 1150
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1136
Number of HSP's gapped (non-prelim): 24
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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