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Search of human proteins with 239049391
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239049391 membrane metallo-endopeptidase-like 1 [Homo
sapiens]
(779 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens] 1582 0.0
gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 832 0.0
gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 832 0.0
gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 832 0.0
gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 832 0.0
gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo sapi... 567 e-161
gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo sapi... 567 e-161
gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo sapi... 567 e-161
gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens] 567 e-161
gi|153945836 endothelin converting enzyme 2 isoform E [Homo sapi... 548 e-156
gi|153945771 endothelin converting enzyme 2 isoform D [Homo sapi... 548 e-156
gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens] 548 e-156
gi|153945761 endothelin converting enzyme 2 isoform A [Homo sapi... 548 e-156
gi|90403592 phosphate-regulating neutral endopeptidase [Homo sap... 505 e-143
gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens] 477 e-134
gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens] 253 5e-67
gi|169217962 PREDICTED: similar to phosphodiesterase 4D interact... 36 0.12
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 36 0.12
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 35 0.20
gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens] 34 0.46
gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens] 34 0.46
gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens] 34 0.46
gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens] 34 0.46
gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens] 34 0.46
gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens] 34 0.46
gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens] 34 0.46
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 34 0.59
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 34 0.59
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 34 0.59
gi|149363638 septin 8 isoform c [Homo sapiens] 33 0.78
>gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens]
Length = 779
Score = 1582 bits (4097), Expect = 0.0
Identities = 779/779 (100%), Positives = 779/779 (100%)
Query: 1 MGKSEGPVGMVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLAS 60
MGKSEGPVGMVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLAS
Sbjct: 1 MGKSEGPVGMVESAGRAGQKRPGFLEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLAS 60
Query: 61 RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFAC 120
RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFAC
Sbjct: 61 RLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFAC 120
Query: 121 GGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSV 180
GGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSV
Sbjct: 121 GGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSV 180
Query: 181 IEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWND 240
IEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWND
Sbjct: 181 IEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWND 240
Query: 241 DQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCL 300
DQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCL
Sbjct: 241 DQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCL 300
Query: 301 VQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLS 360
VQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLS
Sbjct: 301 VQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLS 360
Query: 361 SVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRV 420
SVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRV
Sbjct: 361 SVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRV 420
Query: 421 NYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFV 480
NYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFV
Sbjct: 421 NYRKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFV 480
Query: 481 ETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENS 540
ETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENS
Sbjct: 481 ETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENS 540
Query: 541 LQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ 600
LQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ
Sbjct: 541 LQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ 600
Query: 601 ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSW 660
ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSW
Sbjct: 601 ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSW 660
Query: 661 DLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYA 720
DLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYA
Sbjct: 661 DLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYA 720
Query: 721 QVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
QVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW
Sbjct: 721 QVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 832 bits (2149), Expect = 0.0
Identities = 382/696 (54%), Positives = 529/696 (76%), Gaps = 5/696 (0%)
Query: 88 VCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELE 147
+C + C+ +AAR++QNMD TTEPC DF+++ACGGWL+R+VIPET+SRY FD+LRDELE
Sbjct: 56 ICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELE 115
Query: 148 VILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWN 207
V+LK VL+ +D AV+KA+ LYRSC+N+S I+ RG +PLL +L + GWPVA + W
Sbjct: 116 VVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWE 175
Query: 208 ETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNG 267
+ G W E+ +A +NS++ ++VLI+LF+ DD+NS H+I+IDQP LG+PSR+YY
Sbjct: 176 QKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECT 235
Query: 268 GSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHD 327
G ++ AY+ FM+SVA L+R++ LP D + +M +V+ELE ++A AT E+R+D
Sbjct: 236 GIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRND 295
Query: 328 VIALYHRMGLEELQSQFGL----KGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+ LY++M L ++Q+ F L K F+W F ++S+V I + +E+VVVY YL L
Sbjct: 296 PMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKL 355
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYV 443
+ I+ YSAR +QN + WR ++D + SLS+ +K++R +RKAL+GT E WR C YV
Sbjct: 356 KPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYV 415
Query: 444 NSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMS 503
N NMENAVG LYV AF G+SK +V +LI ++R VF++TLD+L WMD E+KK+A+EKA++
Sbjct: 416 NGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALA 475
Query: 504 IREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNL 563
I+E+IG+PD I+ N+ L+ EY LN+ ED YFEN +QNLK + L+KLREKVD +
Sbjct: 476 IKERIGYPDDIVSNDNK-LNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE 534
Query: 564 WIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNG 623
WI GAAVVNAFYS RNQIVFPAGILQPPFFS +Q +LN+GGIGMVIGHEITHGFDDNG
Sbjct: 535 WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNG 594
Query: 624 RNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGG 683
RNF+K+G+++DWW+ S +F+EQS+CM+YQYGN+SWDLA Q++NG NTLGENIADNGG
Sbjct: 595 RNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGG 654
Query: 684 VRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSP 743
+ QAY+AY ++ + G+++ LPGLDL H+QLFF+N+AQVWCG+YRPE+A+ SIKTDVHSP
Sbjct: 655 LGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSP 714
Query: 744 LKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+R++G+LQN A F++ FHC + + M+P+++CRVW
Sbjct: 715 GNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 832 bits (2149), Expect = 0.0
Identities = 382/696 (54%), Positives = 529/696 (76%), Gaps = 5/696 (0%)
Query: 88 VCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELE 147
+C + C+ +AAR++QNMD TTEPC DF+++ACGGWL+R+VIPET+SRY FD+LRDELE
Sbjct: 56 ICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELE 115
Query: 148 VILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWN 207
V+LK VL+ +D AV+KA+ LYRSC+N+S I+ RG +PLL +L + GWPVA + W
Sbjct: 116 VVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWE 175
Query: 208 ETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNG 267
+ G W E+ +A +NS++ ++VLI+LF+ DD+NS H+I+IDQP LG+PSR+YY
Sbjct: 176 QKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECT 235
Query: 268 GSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHD 327
G ++ AY+ FM+SVA L+R++ LP D + +M +V+ELE ++A AT E+R+D
Sbjct: 236 GIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRND 295
Query: 328 VIALYHRMGLEELQSQFGL----KGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+ LY++M L ++Q+ F L K F+W F ++S+V I + +E+VVVY YL L
Sbjct: 296 PMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKL 355
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYV 443
+ I+ YSAR +QN + WR ++D + SLS+ +K++R +RKAL+GT E WR C YV
Sbjct: 356 KPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYV 415
Query: 444 NSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMS 503
N NMENAVG LYV AF G+SK +V +LI ++R VF++TLD+L WMD E+KK+A+EKA++
Sbjct: 416 NGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALA 475
Query: 504 IREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNL 563
I+E+IG+PD I+ N+ L+ EY LN+ ED YFEN +QNLK + L+KLREKVD +
Sbjct: 476 IKERIGYPDDIVSNDNK-LNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE 534
Query: 564 WIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNG 623
WI GAAVVNAFYS RNQIVFPAGILQPPFFS +Q +LN+GGIGMVIGHEITHGFDDNG
Sbjct: 535 WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNG 594
Query: 624 RNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGG 683
RNF+K+G+++DWW+ S +F+EQS+CM+YQYGN+SWDLA Q++NG NTLGENIADNGG
Sbjct: 595 RNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGG 654
Query: 684 VRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSP 743
+ QAY+AY ++ + G+++ LPGLDL H+QLFF+N+AQVWCG+YRPE+A+ SIKTDVHSP
Sbjct: 655 LGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSP 714
Query: 744 LKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+R++G+LQN A F++ FHC + + M+P+++CRVW
Sbjct: 715 GNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 832 bits (2149), Expect = 0.0
Identities = 382/696 (54%), Positives = 529/696 (76%), Gaps = 5/696 (0%)
Query: 88 VCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELE 147
+C + C+ +AAR++QNMD TTEPC DF+++ACGGWL+R+VIPET+SRY FD+LRDELE
Sbjct: 56 ICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELE 115
Query: 148 VILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWN 207
V+LK VL+ +D AV+KA+ LYRSC+N+S I+ RG +PLL +L + GWPVA + W
Sbjct: 116 VVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWE 175
Query: 208 ETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNG 267
+ G W E+ +A +NS++ ++VLI+LF+ DD+NS H+I+IDQP LG+PSR+YY
Sbjct: 176 QKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECT 235
Query: 268 GSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHD 327
G ++ AY+ FM+SVA L+R++ LP D + +M +V+ELE ++A AT E+R+D
Sbjct: 236 GIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRND 295
Query: 328 VIALYHRMGLEELQSQFGL----KGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+ LY++M L ++Q+ F L K F+W F ++S+V I + +E+VVVY YL L
Sbjct: 296 PMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKL 355
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYV 443
+ I+ YSAR +QN + WR ++D + SLS+ +K++R +RKAL+GT E WR C YV
Sbjct: 356 KPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYV 415
Query: 444 NSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMS 503
N NMENAVG LYV AF G+SK +V +LI ++R VF++TLD+L WMD E+KK+A+EKA++
Sbjct: 416 NGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALA 475
Query: 504 IREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNL 563
I+E+IG+PD I+ N+ L+ EY LN+ ED YFEN +QNLK + L+KLREKVD +
Sbjct: 476 IKERIGYPDDIVSNDNK-LNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE 534
Query: 564 WIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNG 623
WI GAAVVNAFYS RNQIVFPAGILQPPFFS +Q +LN+GGIGMVIGHEITHGFDDNG
Sbjct: 535 WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNG 594
Query: 624 RNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGG 683
RNF+K+G+++DWW+ S +F+EQS+CM+YQYGN+SWDLA Q++NG NTLGENIADNGG
Sbjct: 595 RNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGG 654
Query: 684 VRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSP 743
+ QAY+AY ++ + G+++ LPGLDL H+QLFF+N+AQVWCG+YRPE+A+ SIKTDVHSP
Sbjct: 655 LGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSP 714
Query: 744 LKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+R++G+LQN A F++ FHC + + M+P+++CRVW
Sbjct: 715 GNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 832 bits (2149), Expect = 0.0
Identities = 382/696 (54%), Positives = 529/696 (76%), Gaps = 5/696 (0%)
Query: 88 VCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELE 147
+C + C+ +AAR++QNMD TTEPC DF+++ACGGWL+R+VIPET+SRY FD+LRDELE
Sbjct: 56 ICKSSDCIKSAARLIQNMDATTEPCTDFFKYACGGWLKRNVIPETSSRYGNFDILRDELE 115
Query: 148 VILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWN 207
V+LK VL+ +D AV+KA+ LYRSC+N+S I+ RG +PLL +L + GWPVA + W
Sbjct: 116 VVLKDVLQEPKTEDIVAVQKAKALYRSCINESAIDSRGGEPLLKLLPDIYGWPVATENWE 175
Query: 208 ETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNG 267
+ G W E+ +A +NS++ ++VLI+LF+ DD+NS H+I+IDQP LG+PSR+YY
Sbjct: 176 QKYGASWTAEKAIAQLNSKYGKKVLINLFVGTDDKNSVNHVIHIDQPRLGLPSRDYYECT 235
Query: 268 GSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHD 327
G ++ AY+ FM+SVA L+R++ LP D + +M +V+ELE ++A AT E+R+D
Sbjct: 236 GIYKEACTAYVDFMISVARLIRQEERLPIDENQLALEMNKVMELEKEIANATAKPEDRND 295
Query: 328 VIALYHRMGLEELQSQFGL----KGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+ LY++M L ++Q+ F L K F+W F ++S+V I + +E+VVVY YL L
Sbjct: 296 PMLLYNKMTLAQIQNNFSLEINGKPFSWLNFTNEIMSTVNISITNEEDVVVYAPEYLTKL 355
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYV 443
+ I+ YSAR +QN + WR ++D + SLS+ +K++R +RKAL+GT E WR C YV
Sbjct: 356 KPILTKYSARDLQNLMSWRFIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANYV 415
Query: 444 NSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMS 503
N NMENAVG LYV AF G+SK +V +LI ++R VF++TLD+L WMD E+KK+A+EKA++
Sbjct: 416 NGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKRAEEKALA 475
Query: 504 IREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNL 563
I+E+IG+PD I+ N+ L+ EY LN+ ED YFEN +QNLK + L+KLREKVD +
Sbjct: 476 IKERIGYPDDIVSNDNK-LNNEYLELNYKEDEYFENIIQNLKFSQSKQLKKLREKVDKDE 534
Query: 564 WIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDNG 623
WI GAAVVNAFYS RNQIVFPAGILQPPFFS +Q +LN+GGIGMVIGHEITHGFDDNG
Sbjct: 535 WISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNG 594
Query: 624 RNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGG 683
RNF+K+G+++DWW+ S +F+EQS+CM+YQYGN+SWDLA Q++NG NTLGENIADNGG
Sbjct: 595 RNFNKDGDLVDWWTQQSASNFKEQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGG 654
Query: 684 VRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSP 743
+ QAY+AY ++ + G+++ LPGLDL H+QLFF+N+AQVWCG+YRPE+A+ SIKTDVHSP
Sbjct: 655 LGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSP 714
Query: 744 LKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+R++G+LQN A F++ FHC + + M+P+++CRVW
Sbjct: 715 GNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW 750
>gi|164519140 endothelin converting enzyme 1 isoform 2 [Homo
sapiens]
Length = 767
Score = 567 bits (1461), Expect = e-161
Identities = 281/707 (39%), Positives = 433/707 (61%), Gaps = 29/707 (4%)
Query: 78 GIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYS 137
GI VC + CV + IL +MDPT +PC DF+ +ACGGW++ + +P+ +SR+
Sbjct: 85 GIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWG 144
Query: 138 IFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVG 197
F L + + I+K +LENSTA A KA+ YR+CMN++ IE+ ++PL++++E +G
Sbjct: 145 TFSNLWEHNQAIIKHLLENSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLG 204
Query: 198 GW----PVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 253
GW P A D + +T L ++ + + +++ D +NS+ ++I +DQ
Sbjct: 205 GWNITGPWAKDNFQDT----------LQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQ 254
Query: 254 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
LG+PSR+YY N N KV YL +MV + LL D ++ M Q+L+ ET
Sbjct: 255 SGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFET 309
Query: 314 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 373
LA T+PQE+R D +YH++ ELQ+ NW F+ T+ V+I E +V
Sbjct: 310 ALANITIPQEKRRDEELIYHKVTAAELQTL--APAINWLPFLNTIFYPVEIN--ESEPIV 365
Query: 374 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 433
VY YL+ + +I+T + NY++W LV L QRF+D + + ++GT
Sbjct: 366 VYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTC 425
Query: 434 V-RWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEE 492
+ RW+ CV +N+ A+G ++V+ F DSKS+ E+I +++ F E+L L WMDEE
Sbjct: 426 LPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEE 485
Query: 493 SKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSL 552
++K A+EKA +I IG+P++I++ + LD+ +++ DLYFEN+++ + +
Sbjct: 486 TRKSAKEKADAIYNMIGYPNFIMDP--KELDKVFNDYTAVPDLYFENAMRFFNFSWRVTA 543
Query: 553 RKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIG 612
+LR+ + + W + +VNA+YSP +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+G
Sbjct: 544 DQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVG 603
Query: 613 HEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFN 672
HE+TH FDD GR +DK+GN+ WW N S + F+ Q+ECM+ QY NYS + + VNG +
Sbjct: 604 HELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRH 660
Query: 673 TLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFA 732
TLGENIADNGG++ AY+AY W+ + G + LP L LT+ QLFF+ +AQVWC PE +
Sbjct: 661 TLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESS 720
Query: 733 IQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+ + TD HSP ++RV+GSL N F++ F C G+PM+P +C VW
Sbjct: 721 HEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 767
>gi|164519138 endothelin converting enzyme 1 isoform 4 [Homo
sapiens]
Length = 754
Score = 567 bits (1461), Expect = e-161
Identities = 281/707 (39%), Positives = 433/707 (61%), Gaps = 29/707 (4%)
Query: 78 GIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYS 137
GI VC + CV + IL +MDPT +PC DF+ +ACGGW++ + +P+ +SR+
Sbjct: 72 GIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWG 131
Query: 138 IFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVG 197
F L + + I+K +LENSTA A KA+ YR+CMN++ IE+ ++PL++++E +G
Sbjct: 132 TFSNLWEHNQAIIKHLLENSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLG 191
Query: 198 GW----PVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 253
GW P A D + +T L ++ + + +++ D +NS+ ++I +DQ
Sbjct: 192 GWNITGPWAKDNFQDT----------LQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQ 241
Query: 254 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
LG+PSR+YY N N KV YL +MV + LL D ++ M Q+L+ ET
Sbjct: 242 SGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFET 296
Query: 314 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 373
LA T+PQE+R D +YH++ ELQ+ NW F+ T+ V+I E +V
Sbjct: 297 ALANITIPQEKRRDEELIYHKVTAAELQTL--APAINWLPFLNTIFYPVEIN--ESEPIV 352
Query: 374 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 433
VY YL+ + +I+T + NY++W LV L QRF+D + + ++GT
Sbjct: 353 VYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTC 412
Query: 434 V-RWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEE 492
+ RW+ CV +N+ A+G ++V+ F DSKS+ E+I +++ F E+L L WMDEE
Sbjct: 413 LPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEE 472
Query: 493 SKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSL 552
++K A+EKA +I IG+P++I++ + LD+ +++ DLYFEN+++ + +
Sbjct: 473 TRKSAKEKADAIYNMIGYPNFIMDP--KELDKVFNDYTAVPDLYFENAMRFFNFSWRVTA 530
Query: 553 RKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIG 612
+LR+ + + W + +VNA+YSP +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+G
Sbjct: 531 DQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVG 590
Query: 613 HEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFN 672
HE+TH FDD GR +DK+GN+ WW N S + F+ Q+ECM+ QY NYS + + VNG +
Sbjct: 591 HELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRH 647
Query: 673 TLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFA 732
TLGENIADNGG++ AY+AY W+ + G + LP L LT+ QLFF+ +AQVWC PE +
Sbjct: 648 TLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESS 707
Query: 733 IQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+ + TD HSP ++RV+GSL N F++ F C G+PM+P +C VW
Sbjct: 708 HEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 754
>gi|164519136 endothelin converting enzyme 1 isoform 3 [Homo
sapiens]
Length = 758
Score = 567 bits (1461), Expect = e-161
Identities = 281/707 (39%), Positives = 433/707 (61%), Gaps = 29/707 (4%)
Query: 78 GIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYS 137
GI VC + CV + IL +MDPT +PC DF+ +ACGGW++ + +P+ +SR+
Sbjct: 76 GIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWG 135
Query: 138 IFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVG 197
F L + + I+K +LENSTA A KA+ YR+CMN++ IE+ ++PL++++E +G
Sbjct: 136 TFSNLWEHNQAIIKHLLENSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLG 195
Query: 198 GW----PVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 253
GW P A D + +T L ++ + + +++ D +NS+ ++I +DQ
Sbjct: 196 GWNITGPWAKDNFQDT----------LQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQ 245
Query: 254 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
LG+PSR+YY N N KV YL +MV + LL D ++ M Q+L+ ET
Sbjct: 246 SGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFET 300
Query: 314 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 373
LA T+PQE+R D +YH++ ELQ+ NW F+ T+ V+I E +V
Sbjct: 301 ALANITIPQEKRRDEELIYHKVTAAELQTL--APAINWLPFLNTIFYPVEIN--ESEPIV 356
Query: 374 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 433
VY YL+ + +I+T + NY++W LV L QRF+D + + ++GT
Sbjct: 357 VYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTC 416
Query: 434 V-RWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEE 492
+ RW+ CV +N+ A+G ++V+ F DSKS+ E+I +++ F E+L L WMDEE
Sbjct: 417 LPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEE 476
Query: 493 SKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSL 552
++K A+EKA +I IG+P++I++ + LD+ +++ DLYFEN+++ + +
Sbjct: 477 TRKSAKEKADAIYNMIGYPNFIMDP--KELDKVFNDYTAVPDLYFENAMRFFNFSWRVTA 534
Query: 553 RKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIG 612
+LR+ + + W + +VNA+YSP +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+G
Sbjct: 535 DQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVG 594
Query: 613 HEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFN 672
HE+TH FDD GR +DK+GN+ WW N S + F+ Q+ECM+ QY NYS + + VNG +
Sbjct: 595 HELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRH 651
Query: 673 TLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFA 732
TLGENIADNGG++ AY+AY W+ + G + LP L LT+ QLFF+ +AQVWC PE +
Sbjct: 652 TLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESS 711
Query: 733 IQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+ + TD HSP ++RV+GSL N F++ F C G+PM+P +C VW
Sbjct: 712 HEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 758
>gi|4503443 endothelin converting enzyme 1 isoform 1 [Homo sapiens]
Length = 770
Score = 567 bits (1461), Expect = e-161
Identities = 281/707 (39%), Positives = 433/707 (61%), Gaps = 29/707 (4%)
Query: 78 GIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYS 137
GI VC + CV + IL +MDPT +PC DF+ +ACGGW++ + +P+ +SR+
Sbjct: 88 GIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWG 147
Query: 138 IFDVLRDELEVILKAVLENSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVG 197
F L + + I+K +LENSTA A KA+ YR+CMN++ IE+ ++PL++++E +G
Sbjct: 148 TFSNLWEHNQAIIKHLLENSTASVSEAERKAQVYYRACMNETRIEELRAKPLMELIERLG 207
Query: 198 GW----PVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQ 253
GW P A D + +T L ++ + + +++ D +NS+ ++I +DQ
Sbjct: 208 GWNITGPWAKDNFQDT----------LQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQ 257
Query: 254 PTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
LG+PSR+YY N N KV YL +MV + LL D ++ M Q+L+ ET
Sbjct: 258 SGLGLPSRDYYLNKTENEKVLTGYLNYMVQLGKLLGGG-----DEEAIRPQMQQILDFET 312
Query: 314 QLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVV 373
LA T+PQE+R D +YH++ ELQ+ NW F+ T+ V+I E +V
Sbjct: 313 ALANITIPQEKRRDEELIYHKVTAAELQTL--APAINWLPFLNTIFYPVEIN--ESEPIV 368
Query: 374 VYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEE 433
VY YL+ + +I+T + NY++W LV L QRF+D + + ++GT
Sbjct: 369 VYDKEYLEQISTLINTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTC 428
Query: 434 V-RWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEE 492
+ RW+ CV +N+ A+G ++V+ F DSKS+ E+I +++ F E+L L WMDEE
Sbjct: 429 LPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEE 488
Query: 493 SKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSL 552
++K A+EKA +I IG+P++I++ + LD+ +++ DLYFEN+++ + +
Sbjct: 489 TRKSAKEKADAIYNMIGYPNFIMDP--KELDKVFNDYTAVPDLYFENAMRFFNFSWRVTA 546
Query: 553 RKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIG 612
+LR+ + + W + +VNA+YSP +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+G
Sbjct: 547 DQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVG 606
Query: 613 HEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFN 672
HE+TH FDD GR +DK+GN+ WW N S + F+ Q+ECM+ QY NYS + + VNG +
Sbjct: 607 HELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYS---VNGEPVNGRH 663
Query: 673 TLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFA 732
TLGENIADNGG++ AY+AY W+ + G + LP L LT+ QLFF+ +AQVWC PE +
Sbjct: 664 TLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESS 723
Query: 733 IQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+ + TD HSP ++RV+GSL N F++ F C G+PM+P +C VW
Sbjct: 724 HEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770
>gi|153945836 endothelin converting enzyme 2 isoform E [Homo
sapiens]
Length = 765
Score = 548 bits (1412), Expect = e-156
Identities = 298/757 (39%), Positives = 429/757 (56%), Gaps = 56/757 (7%)
Query: 25 LEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQE 84
L G LLL L+ LVALGV Y R P
Sbjct: 63 LAGASLLLAALLLGCLVALGVQY-------------------------HRDPS------- 90
Query: 85 VSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRD 144
C T C+ A +IL+++D PC+DFYQF+CGGW+RR+ +P+ SR++ F+ L D
Sbjct: 91 -HSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWD 149
Query: 145 ELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAM 203
+ + ILK +LEN+T E K + Y SC+ IE+ G+QPL D++E +GGW +
Sbjct: 150 QNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNIT- 208
Query: 204 DRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREY 263
W++ +E L + + ++I D ++S+ ++I +DQ L +PSR+Y
Sbjct: 209 GPWDQDNFME-----VLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 263
Query: 264 YFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQE 323
Y N +N KV AYL +M + LL R E M QVLELE QLA TVPQ+
Sbjct: 264 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR------EQMQQVLELEIQLANITVPQD 317
Query: 324 ERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+R D +YH+M + ELQ+ +W F+ +LS ++L E VVVYG+ YLQ +
Sbjct: 318 QRRDEEKIYHKMSISELQAL--APSMDWLEFLSFLLSP--LELSDSEPVVVYGMDYLQQV 373
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEV-RWRECVGY 442
+I+ + NYL+W LV SL +RF+ + + L+GT V RW+ C+
Sbjct: 374 SELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISN 433
Query: 443 VNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAM 502
+ + A+GSL+V+ F SK + +I ++RT F E L +L WMDE++++ A+EKA
Sbjct: 434 TDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKAD 493
Query: 503 SIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPN 562
+I + IG PD+ILE + LD+ Y SED +F+N L A+ +LR+ +
Sbjct: 494 AIYDMIGFPDFILEP--KELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRD 551
Query: 563 LWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDN 622
W + VNA+Y P +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+GHE+TH FDD
Sbjct: 552 QWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQ 611
Query: 623 GRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNG 682
GR +DK GN+ WW N S FR + CM QY Y + + +NG TLGENIADNG
Sbjct: 612 GREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQ---VNGERLNGRQTLGENIADNG 668
Query: 683 GVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHS 742
G++ AY AY W+ + G++QQLP + LT+ QLFF+ +AQVWC PE + + + TD HS
Sbjct: 669 GLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHS 728
Query: 743 PLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
P ++RVLG+L N F F C G+PM+P + C VW
Sbjct: 729 PARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765
>gi|153945771 endothelin converting enzyme 2 isoform D [Homo
sapiens]
Length = 811
Score = 548 bits (1412), Expect = e-156
Identities = 298/757 (39%), Positives = 429/757 (56%), Gaps = 56/757 (7%)
Query: 25 LEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQE 84
L G LLL L+ LVALGV Y R P
Sbjct: 109 LAGASLLLAALLLGCLVALGVQY-------------------------HRDPS------- 136
Query: 85 VSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRD 144
C T C+ A +IL+++D PC+DFYQF+CGGW+RR+ +P+ SR++ F+ L D
Sbjct: 137 -HSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWD 195
Query: 145 ELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAM 203
+ + ILK +LEN+T E K + Y SC+ IE+ G+QPL D++E +GGW +
Sbjct: 196 QNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNIT- 254
Query: 204 DRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREY 263
W++ +E L + + ++I D ++S+ ++I +DQ L +PSR+Y
Sbjct: 255 GPWDQDNFME-----VLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 309
Query: 264 YFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQE 323
Y N +N KV AYL +M + LL R E M QVLELE QLA TVPQ+
Sbjct: 310 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR------EQMQQVLELEIQLANITVPQD 363
Query: 324 ERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+R D +YH+M + ELQ+ +W F+ +LS ++L E VVVYG+ YLQ +
Sbjct: 364 QRRDEEKIYHKMSISELQAL--APSMDWLEFLSFLLSP--LELSDSEPVVVYGMDYLQQV 419
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEV-RWRECVGY 442
+I+ + NYL+W LV SL +RF+ + + L+GT V RW+ C+
Sbjct: 420 SELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISN 479
Query: 443 VNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAM 502
+ + A+GSL+V+ F SK + +I ++RT F E L +L WMDE++++ A+EKA
Sbjct: 480 TDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKAD 539
Query: 503 SIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPN 562
+I + IG PD+ILE + LD+ Y SED +F+N L A+ +LR+ +
Sbjct: 540 AIYDMIGFPDFILEP--KELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRD 597
Query: 563 LWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDN 622
W + VNA+Y P +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+GHE+TH FDD
Sbjct: 598 QWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQ 657
Query: 623 GRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNG 682
GR +DK GN+ WW N S FR + CM QY Y + + +NG TLGENIADNG
Sbjct: 658 GREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQ---VNGERLNGRQTLGENIADNG 714
Query: 683 GVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHS 742
G++ AY AY W+ + G++QQLP + LT+ QLFF+ +AQVWC PE + + + TD HS
Sbjct: 715 GLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHS 774
Query: 743 PLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
P ++RVLG+L N F F C G+PM+P + C VW
Sbjct: 775 PARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811
>gi|82617560 endothelin converting enzyme 2 isoform B [Homo sapiens]
Length = 736
Score = 548 bits (1412), Expect = e-156
Identities = 298/757 (39%), Positives = 429/757 (56%), Gaps = 56/757 (7%)
Query: 25 LEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQE 84
L G LLL L+ LVALGV Y R P
Sbjct: 34 LAGASLLLAALLLGCLVALGVQY-------------------------HRDPS------- 61
Query: 85 VSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRD 144
C T C+ A +IL+++D PC+DFYQF+CGGW+RR+ +P+ SR++ F+ L D
Sbjct: 62 -HSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWD 120
Query: 145 ELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAM 203
+ + ILK +LEN+T E K + Y SC+ IE+ G+QPL D++E +GGW +
Sbjct: 121 QNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNIT- 179
Query: 204 DRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREY 263
W++ +E L + + ++I D ++S+ ++I +DQ L +PSR+Y
Sbjct: 180 GPWDQDNFME-----VLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 234
Query: 264 YFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQE 323
Y N +N KV AYL +M + LL R E M QVLELE QLA TVPQ+
Sbjct: 235 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR------EQMQQVLELEIQLANITVPQD 288
Query: 324 ERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+R D +YH+M + ELQ+ +W F+ +LS ++L E VVVYG+ YLQ +
Sbjct: 289 QRRDEEKIYHKMSISELQAL--APSMDWLEFLSFLLSP--LELSDSEPVVVYGMDYLQQV 344
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEV-RWRECVGY 442
+I+ + NYL+W LV SL +RF+ + + L+GT V RW+ C+
Sbjct: 345 SELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISN 404
Query: 443 VNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAM 502
+ + A+GSL+V+ F SK + +I ++RT F E L +L WMDE++++ A+EKA
Sbjct: 405 TDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKAD 464
Query: 503 SIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPN 562
+I + IG PD+ILE + LD+ Y SED +F+N L A+ +LR+ +
Sbjct: 465 AIYDMIGFPDFILEP--KELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRD 522
Query: 563 LWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDN 622
W + VNA+Y P +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+GHE+TH FDD
Sbjct: 523 QWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQ 582
Query: 623 GRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNG 682
GR +DK GN+ WW N S FR + CM QY Y + + +NG TLGENIADNG
Sbjct: 583 GREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQ---VNGERLNGRQTLGENIADNG 639
Query: 683 GVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHS 742
G++ AY AY W+ + G++QQLP + LT+ QLFF+ +AQVWC PE + + + TD HS
Sbjct: 640 GLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHS 699
Query: 743 PLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
P ++RVLG+L N F F C G+PM+P + C VW
Sbjct: 700 PARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 736
>gi|153945761 endothelin converting enzyme 2 isoform A [Homo
sapiens]
Length = 883
Score = 548 bits (1412), Expect = e-156
Identities = 298/757 (39%), Positives = 429/757 (56%), Gaps = 56/757 (7%)
Query: 25 LEGGLLLLLLLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQE 84
L G LLL L+ LVALGV Y R P
Sbjct: 181 LAGASLLLAALLLGCLVALGVQY-------------------------HRDPS------- 208
Query: 85 VSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRD 144
C T C+ A +IL+++D PC+DFYQF+CGGW+RR+ +P+ SR++ F+ L D
Sbjct: 209 -HSTCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWD 267
Query: 145 ELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAM 203
+ + ILK +LEN+T E K + Y SC+ IE+ G+QPL D++E +GGW +
Sbjct: 268 QNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNIT- 326
Query: 204 DRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREY 263
W++ +E L + + ++I D ++S+ ++I +DQ L +PSR+Y
Sbjct: 327 GPWDQDNFME-----VLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDY 381
Query: 264 YFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQE 323
Y N +N KV AYL +M + LL R E M QVLELE QLA TVPQ+
Sbjct: 382 YLNRTANEKVLTAYLDYMEELGMLLGGRPTSTR------EQMQQVLELEIQLANITVPQD 435
Query: 324 ERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNL 383
+R D +YH+M + ELQ+ +W F+ +LS ++L E VVVYG+ YLQ +
Sbjct: 436 QRRDEEKIYHKMSISELQAL--APSMDWLEFLSFLLSP--LELSDSEPVVVYGMDYLQQV 491
Query: 384 ENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEV-RWRECVGY 442
+I+ + NYL+W LV SL +RF+ + + L+GT V RW+ C+
Sbjct: 492 SELINRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISN 551
Query: 443 VNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAM 502
+ + A+GSL+V+ F SK + +I ++RT F E L +L WMDE++++ A+EKA
Sbjct: 552 TDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKAD 611
Query: 503 SIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPN 562
+I + IG PD+ILE + LD+ Y SED +F+N L A+ +LR+ +
Sbjct: 612 AIYDMIGFPDFILEP--KELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRD 669
Query: 563 LWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGFDDN 622
W + VNA+Y P +N+IVFPAGILQ PF+++ P+ALNFGGIG+V+GHE+TH FDD
Sbjct: 670 QWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQ 729
Query: 623 GRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNG 682
GR +DK GN+ WW N S FR + CM QY Y + + +NG TLGENIADNG
Sbjct: 730 GREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQ---VNGERLNGRQTLGENIADNG 786
Query: 683 GVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHS 742
G++ AY AY W+ + G++QQLP + LT+ QLFF+ +AQVWC PE + + + TD HS
Sbjct: 787 GLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHS 846
Query: 743 PLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
P ++RVLG+L N F F C G+PM+P + C VW
Sbjct: 847 PARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883
>gi|90403592 phosphate-regulating neutral endopeptidase [Homo
sapiens]
Length = 749
Score = 505 bits (1301), Expect = e-143
Identities = 284/723 (39%), Positives = 427/723 (59%), Gaps = 35/723 (4%)
Query: 77 RGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRY 136
+G+ Q E C P C+ AAA IL ++ + +PCD+F++FAC GW+ + IPE Y
Sbjct: 42 QGLLSLQAKQEYCLKPECIEAAAAILSKVNLSVDPCDNFFRFACDGWISNNPIPEDMPSY 101
Query: 137 SIFDVLRDELEVILKAVLENSTAK--DRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILE 194
++ LR +++ LK +LE S ++ D A++KA+ LY SCMN+ IEK ++PLL IL
Sbjct: 102 GVYPWLRHNVDLKLKELLEKSISRRRDTEAIQKAKILYSSCMNEKAIEKADAKPLLHILR 161
Query: 195 VVG-GWPVAMDR------WNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRH 247
WPV W+E ++ L + LA Q++ V I L++ DD+ S+ H
Sbjct: 162 HSPFRWPVLESNIGPEGVWSER---KFSLLQTLATFRGQYSNSVFIRLYVSPDDKASNEH 218
Query: 248 IIYIDQPTLGMPSREYYFNGGSNRK-VREAYLQFMVSVATLLREDANLPRDSCLVQEDMV 306
I+ +DQ TL + RE Y + + K R+A +FMV A LL AN R + DM
Sbjct: 219 ILKLDQATLSLAVREDYLDNSTEAKSYRDALYKFMVDTAVLL--GANSSR----AEHDMK 272
Query: 307 QVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKL 366
VL LE ++A+ +P E R A+Y++M + EL + + F+W +I+ V+ +
Sbjct: 273 SVLRLEIKIAEIMIPHENRTSE-AMYNKMNISELSAM--IPQFDWLGYIKKVIDTRLYPH 329
Query: 367 L----PDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNY 422
L P E VVV Y ++L I+ + +TI NYLVWR+V RI +LS+RF+ + +
Sbjct: 330 LKDISPSENVVVRVPQYFKDLFRILGSERKKTIANYLVWRMVYSRIPNLSRRFQYRWLEF 389
Query: 423 RKALFGTMVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVET 482
+ + GT +W +CV ++ S + VG ++V F D K M+ EL++ VR F++
Sbjct: 390 SRVIQGTTTLLPQWDKCVNFIESALPYVVGKMFVDVYFQEDKKEMMEELVEGVRWAFIDM 449
Query: 483 LD-ELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSL 541
L+ E WMD +K+KA+EKA ++ ++G+P++I+ + + ++E+ + FSE YF N L
Sbjct: 450 LEKENEWMDAGTKRKAKEKARAVLAKVGYPEFIMNDTH--VNEDLKAIKFSEADYFGNVL 507
Query: 542 QNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFF-SKEQPQ 600
Q K AQ LR+ V W VNAFYS + NQI FPAG LQ PFF E P+
Sbjct: 508 QTRKYLAQSDFFWLRKAVPKTEWFTNPTTVNAFYSASTNQIRFPAGELQKPFFWGTEYPR 567
Query: 601 ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSW 660
+L++G IG+++GHE THGFD+NGR +DKNGN+ WWS S + F+E+++CMI QY NY W
Sbjct: 568 SLSYGAIGVIVGHEFTHGFDNNGRKYDKNGNLDPWWSTESEEKFKEKTKCMINQYSNYYW 627
Query: 661 DLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWM---AEGGKDQQLPGLDLTHEQLFFI 717
A NV G TLGENIADNGG+R+A++AY KW+ +G ++ LPG+ T+ QLFF+
Sbjct: 628 KKAG-LNVKGKRTLGENIADNGGLREAFRAYRKWINDRRQGLEEPLLPGITFTNNQLFFL 686
Query: 718 NYAQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMH-PKERC 776
+YA V C SYRPE A + ++ HSP ++RV G++ N F F+C + M+ + C
Sbjct: 687 SYAHVRCNSYRPEAAREQVQIGAHSPPQFRVNGAISNFEEFQKAFNCPPNSTMNRGMDSC 746
Query: 777 RVW 779
R+W
Sbjct: 747 RLW 749
>gi|157426891 endothelin converting enzyme-like 1 [Homo sapiens]
Length = 775
Score = 477 bits (1228), Expect = e-134
Identities = 257/710 (36%), Positives = 397/710 (55%), Gaps = 36/710 (5%)
Query: 76 PRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSR 135
P G PE + + AA + N+D + +PC DFY FACGGWLRRH IP+
Sbjct: 96 PEGCPERKAFAR---------AARFLAANLDASIDPCQDFYSFACGGWLRRHAIPDDKLT 146
Query: 136 YSIFDVLRDELEVILKAVLENSTAKDRPAVE-KARTLYRSCMNQSVIEKRGSQPLLDILE 194
Y + ++ E L+ +L A + K R +RSC++ IE+ G +P+L+++E
Sbjct: 147 YGTIAAIGEQNEERLRRLLARPGGGPGGAAQRKVRAFFRSCLDMREIERLGPRPMLEVIE 206
Query: 195 VVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQP 254
GGW + V W+L R L ++ L L + DD+NSSR++I IDQ
Sbjct: 207 DCGGWDLGGAEERPGVAARWDLNRLLYKAQGVYSAAALFSLTVSLDDRNSSRYVIRIDQD 266
Query: 255 TLGMPSREYYF-NGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELET 313
L +P R Y + K+ AY FM V +LL DA V++ ++L++E
Sbjct: 267 GLTLPERTLYLAQDEDSEKILAAYRVFMERVLSLLGADA--------VEQKAQEILQVEQ 318
Query: 314 QLAKATVPQEE--RHDVIALYHRMGLEELQSQFGLKGFNWTL--FIQTVLSSVKIKLLPD 369
QLA TV + + R DV ++Y+++ L +LQ + W L Q S +
Sbjct: 319 QLANITVSEHDDLRRDVSSMYNKVTLGQLQKITPHLRWKWLLDQIFQEDFSE-------E 371
Query: 370 EEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGT 429
EEVV+ Y+Q + +I + R + NYLVWR+V+ LS F++ + + G+
Sbjct: 372 EEVVLLATDYMQQVSQLIRSTPHRVLHNYLVWRVVVVLSEHLSPPFREALHELAQEMEGS 431
Query: 430 MVEEVRWRECVGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWM 489
+ R C+G N + A+G+L+V E F SK+ V++L++ ++ + + L+EL WM
Sbjct: 432 DKPQELARVCLGQANRHFGMALGALFVHEHFSAASKAKVQQLVEDIKYILGQRLEELDWM 491
Query: 490 DEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQ 549
D E++ A+ K + +G+PD++L+ +D+EY E YF+N L +++ Q
Sbjct: 492 DAETRAAARAKLQYMMVMVGYPDFLLKP--DAVDKEYE-FEVHEKTYFKNILNSIRFSIQ 548
Query: 550 RSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGM 609
S++K+R++VD + W++ +NA+Y PN+NQ+VFPAGILQP + + PQ+LN+GGIG
Sbjct: 549 LSVKKIRQEVDKSTWLLPPQALNAYYLPNKNQMVFPAGILQPTLYDPDFPQSLNYGGIGT 608
Query: 610 VIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVN 669
+IGHE+THG+DD G +D++GN++ WW+ S F ++EC++ Y N++ Q VN
Sbjct: 609 IIGHELTHGYDDWGGQYDRSGNLLHWWTEASYSRFLRKAECIVRLYDNFT---VYNQRVN 665
Query: 670 GFNTLGENIADNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRP 729
G +TLGENIAD GG++ AY AY KW+ E G + LP L TH+QLFFI +AQ WC R
Sbjct: 666 GKHTLGENIADMGGLKLAYHAYQKWVREHGPEHPLPRLKYTHDQLFFIAFAQNWCIKRRS 725
Query: 730 EFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
+ + TD H+P YRVLGS+ F FHC + +PM+P +C VW
Sbjct: 726 QSIYLQVLTDKHAPEHYRVLGSVSQFEEFGRAFHCPKDSPMNPAHKCSVW 775
>gi|4557691 Kell blood group, metallo-endopeptidase [Homo sapiens]
Length = 732
Score = 253 bits (646), Expect = 5e-67
Identities = 189/700 (27%), Positives = 327/700 (46%), Gaps = 53/700 (7%)
Query: 89 CTTPGCVIAAARILQNMDPTTEPCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELEV 148
C T C+ L + + + PC DF+ FACG ETN+ F L + +
Sbjct: 77 CETSVCLDLRDHYLASGNTSVAPCTDFFSFACGR------AKETNNS---FQELATKNKN 127
Query: 149 ILKAVLE-NSTAKDRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWN 207
L+ +LE ++ EKA Y SCM+ IE G+ PL ++E +GGW ++ +W
Sbjct: 128 RLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRIS-GKWT 186
Query: 208 ETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNG 267
R L L+ SQ+ ++ + +I IDQP +P ++
Sbjct: 187 SL-----NFNRTLRLLMSQYGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQK 241
Query: 268 GSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHD 327
+ RE YL ++ + TLL D + VQE + + ++L + P E+R
Sbjct: 242 IYAQIFRE-YLTYLNQLGTLLGGDPSK------VQEHSSLSISITSRLFQFLRPLEQRRA 294
Query: 328 VIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENII 387
L+ + +++L+ +W +Q + + + P + +VV+ + YL+N+ ++
Sbjct: 295 QGKLFQMVTIDQLKEM--APAIDWLSCLQATFTPMSLS--PSQSLVVHDVEYLKNMSQLV 350
Query: 388 DTYSART---IQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGT-----MVEEVRWREC 439
+ + +Q++++ LV+ +L +F++ R + L M RW +C
Sbjct: 351 EEMLLKQRDFLQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKC 410
Query: 440 VGYVNSNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQE 499
V + E + +L+VREAF ++S +L +R + L L WM+EE++ AQ+
Sbjct: 411 VEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQD 470
Query: 500 KAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKV 559
K ++ ++G ++ L+ R +EY+++ + ++ L ++ R ++ +
Sbjct: 471 KVAQLQVEMGASEWALKPELAR--QEYNDIQLGSS-FLQSVLSCVRSLRARIVQSFLQPH 527
Query: 560 DPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGGIGMVIGHEITHGF 619
+ W + VNA+YS + + +VFPAG+LQPPFF P+A+NFG G ++ HE+ H F
Sbjct: 528 PQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIF 587
Query: 620 DDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIA 679
G + +E C+ Y ++ L + N T EN A
Sbjct: 588 ----YQLLLPGGCL----ACDNHALQEAHLCLKRHYA--AFPLPSRTSFNDSLTFLENAA 637
Query: 680 DNGGVRQAYKAYLKWMAEGGKDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTD 739
D GG+ A +AY K + + LP LDL+ +Q+FF +YAQV C P+ + D
Sbjct: 638 DVGGLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQVMCRKPSPQDS-----HD 692
Query: 740 VHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW 779
HSP RV G L + AFA F CARG ++P RC++W
Sbjct: 693 THSPPHLRVHGPLSSTPAFARYFRCARGALLNPSSRCQLW 732
>gi|169217962 PREDICTED: similar to phosphodiesterase 4D interacting
protein [Homo sapiens]
Length = 424
Score = 36.2 bits (82), Expect = 0.12
Identities = 42/171 (24%), Positives = 72/171 (42%), Gaps = 13/171 (7%)
Query: 481 ETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENS 540
ET+ + GW EE K+K + ++ + G + L+ R+L + N + +L E
Sbjct: 17 ETMSD-GWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQL 75
Query: 541 LQNLKVGAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQ 600
+ + K G + +L + + I +V SP ++Q + PF +PQ
Sbjct: 76 VLSSKEGNSKLTPELLVHLTSTIERINTELVG---SPGKHQHQEEGNVTVRPF---PRPQ 129
Query: 601 ALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQ-SEC 650
+L+ G V H++ DN G + STQH R Q S+C
Sbjct: 130 SLDLGATFTVDAHQL-----DNQSQPRDPGPQSAFSLPGSTQHLRSQLSQC 175
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 36.2 bits (82), Expect = 0.12
Identities = 27/78 (34%), Positives = 43/78 (55%), Gaps = 5/78 (6%)
Query: 458 EAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMSIREQI---GHPDYI 514
EA +S+S+ EL KV+ + E+LD L + E+ K Q++ + EQI G +
Sbjct: 1472 EASQKESRSLSTELF-KVKNAYEESLDHLETLKREN-KNLQQEISDLTEQIAEGGKHIHE 1529
Query: 515 LEEMNRRLDEEYSNLNFS 532
LE++ ++LD E S L S
Sbjct: 1530 LEKVKKQLDHEKSELQTS 1547
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
sapiens]
Length = 2346
Score = 35.4 bits (80), Expect = 0.20
Identities = 40/165 (24%), Positives = 68/165 (41%), Gaps = 12/165 (7%)
Query: 487 GWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKV 546
GW EE K+K + ++ + G + L+ R+L + N + +L E + + K
Sbjct: 1070 GWEIEEDKEKGEVMVETVVTKEGLSESSLQAEFRKLQGKLKNAHNIINLLKEQLVLSSKE 1129
Query: 547 GAQRSLRKLREKVDPNLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKEQPQALNFGG 606
G + +L + + I +V SP ++Q + PF +PQ+L+ G
Sbjct: 1130 GNSKLTPELLVHLTSTIERINTELVG---SPGKHQHQEEGNVTVRPF---PRPQSLDLGA 1183
Query: 607 IGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQ-SEC 650
V H++ DN G + STQH R Q S+C
Sbjct: 1184 TFTVDAHQL-----DNQSQPRDPGPQSAFSLPGSTQHLRSQLSQC 1223
>gi|21536417 bridging integrator 1 isoform 10 [Homo sapiens]
Length = 409
Score = 34.3 bits (77), Expect = 0.46
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 491 EESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR 550
+ +KKK + K E++ + EEMN L EE +L S ++ N+ Q++ G +
Sbjct: 161 QTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSI-AGLEE 219
Query: 551 SLRKLREKVDPNL 563
+ K K++ NL
Sbjct: 220 NFHKEMSKLNQNL 232
>gi|21536415 bridging integrator 1 isoform 9 [Homo sapiens]
Length = 439
Score = 34.3 bits (77), Expect = 0.46
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 491 EESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR 550
+ +KKK + K E++ + EEMN L EE +L S ++ N+ Q++ G +
Sbjct: 161 QTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSI-AGLEE 219
Query: 551 SLRKLREKVDPNL 563
+ K K++ NL
Sbjct: 220 NFHKEMSKLNQNL 232
>gi|21536413 bridging integrator 1 isoform 7 [Homo sapiens]
Length = 475
Score = 34.3 bits (77), Expect = 0.46
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 491 EESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR 550
+ +KKK + K E++ + EEMN L EE +L S ++ N+ Q++ G +
Sbjct: 161 QTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSI-AGLEE 219
Query: 551 SLRKLREKVDPNL 563
+ K K++ NL
Sbjct: 220 NFHKEMSKLNQNL 232
>gi|21536411 bridging integrator 1 isoform 6 [Homo sapiens]
Length = 482
Score = 34.3 bits (77), Expect = 0.46
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 491 EESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR 550
+ +KKK + K E++ + EEMN L EE +L S ++ N+ Q++ G +
Sbjct: 161 QTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSI-AGLEE 219
Query: 551 SLRKLREKVDPNL 563
+ K K++ NL
Sbjct: 220 NFHKEMSKLNQNL 232
>gi|21536409 bridging integrator 1 isoform 5 [Homo sapiens]
Length = 518
Score = 34.3 bits (77), Expect = 0.46
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 491 EESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR 550
+ +KKK + K E++ + EEMN L EE +L S ++ N+ Q++ G +
Sbjct: 161 QTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSI-AGLEE 219
Query: 551 SLRKLREKVDPNL 563
+ K K++ NL
Sbjct: 220 NFHKEMSKLNQNL 232
>gi|21536407 bridging integrator 1 isoform 4 [Homo sapiens]
Length = 497
Score = 34.3 bits (77), Expect = 0.46
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 491 EESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR 550
+ +KKK + K E++ + EEMN L EE +L S ++ N+ Q++ G +
Sbjct: 161 QTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSI-AGLEE 219
Query: 551 SLRKLREKVDPNL 563
+ K K++ NL
Sbjct: 220 NFHKEMSKLNQNL 232
>gi|4757748 bridging integrator 1 isoform 8 [Homo sapiens]
Length = 454
Score = 34.3 bits (77), Expect = 0.46
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Query: 491 EESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQR 550
+ +KKK + K E++ + EEMN L EE +L S ++ N+ Q++ G +
Sbjct: 161 QTAKKKDEAKIAKAEEELIKAQKVFEEMNVDLQEELPSLWNSRVGFYVNTFQSI-AGLEE 219
Query: 551 SLRKLREKVDPNL 563
+ K K++ NL
Sbjct: 220 NFHKEMSKLNQNL 232
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 33.9 bits (76), Expect = 0.59
Identities = 49/244 (20%), Positives = 115/244 (47%), Gaps = 32/244 (13%)
Query: 270 NRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHDVI 329
N+K+++ + V +A L R + +D C+ +++ E E+ + KA E + V
Sbjct: 1108 NQKIQDNNENYQVGLAEL-RTLMTIEKDQCI--SELISRHEEESNILKA-----ELNKVT 1159
Query: 330 ALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPY---LQNLENI 386
+L+++ E++ + + + LS+++ + DE++ Y +QNLE
Sbjct: 1160 SLHNQAF--EIEKNLKEQIIELQSKLDSELSALERQ--KDEKITQQEEKYEAIIQNLEKD 1215
Query: 387 IDTYSARTIQN--YLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVN 444
+ Q+ L+ +L ++ ++ K+ ++ R+ + ++E+V+
Sbjct: 1216 RQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLE-REVVEKELLEKVK--------- 1265
Query: 445 SNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMSI 504
++EN + ++ GDS S+V EL +K++ + L++L EE +K+ E+ ++
Sbjct: 1266 -HLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQL----EEQEKRKNEEMQNV 1320
Query: 505 REQI 508
R +
Sbjct: 1321 RTSL 1324
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 33.9 bits (76), Expect = 0.59
Identities = 49/244 (20%), Positives = 115/244 (47%), Gaps = 32/244 (13%)
Query: 270 NRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHDVI 329
N+K+++ + V +A L R + +D C+ +++ E E+ + KA E + V
Sbjct: 1108 NQKIQDNNENYQVGLAEL-RTLMTIEKDQCI--SELISRHEEESNILKA-----ELNKVT 1159
Query: 330 ALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPY---LQNLENI 386
+L+++ E++ + + + LS+++ + DE++ Y +QNLE
Sbjct: 1160 SLHNQAF--EIEKNLKEQIIELQSKLDSELSALERQ--KDEKITQQEEKYEAIIQNLEKD 1215
Query: 387 IDTYSARTIQN--YLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVN 444
+ Q+ L+ +L ++ ++ K+ ++ R+ + ++E+V+
Sbjct: 1216 RQKLVSSQEQDREQLIQKLNCEKDEAIQTALKEFKLE-REVVEKELLEKVK--------- 1265
Query: 445 SNMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMSI 504
++EN + ++ GDS S+V EL +K++ + L++L EE +K+ E+ ++
Sbjct: 1266 -HLENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQL----EEQEKRKNEEMQNV 1320
Query: 505 REQI 508
R +
Sbjct: 1321 RTSL 1324
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 33.9 bits (76), Expect = 0.59
Identities = 23/75 (30%), Positives = 44/75 (58%), Gaps = 5/75 (6%)
Query: 458 EAFPGDSKSMVRELIDKVRTVFVETLDELGWMDEESKKKAQEKAMSIREQI---GHPDYI 514
EA +S+S+ EL K++ + E+LD+L + E+ K Q++ + EQI G +
Sbjct: 1472 EASQKESRSLSTELF-KIKNAYEESLDQLETLKREN-KNLQQEISDLTEQIAEGGKRIHE 1529
Query: 515 LEEMNRRLDEEYSNL 529
LE++ +++++E S L
Sbjct: 1530 LEKIKKQVEQEKSEL 1544
>gi|149363638 septin 8 isoform c [Homo sapiens]
Length = 442
Score = 33.5 bits (75), Expect = 0.78
Identities = 38/162 (23%), Positives = 70/162 (43%), Gaps = 19/162 (11%)
Query: 420 VNYRKALFGTMVEEVR----------WREC----VGYVNSNMENAVGSLYVREAFPGDSK 465
V R+ L +E++R +R C +G+ +S+ ++ SL +E + K
Sbjct: 274 VKLREMLIRVNMEDLREQTHSRHYELYRRCKLEEMGFQDSDGDSQPFSL--QETYEAKRK 331
Query: 466 SMVRELIDK---VRTVFVETLDELGWMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRL 522
+ EL K +R +FV + E +E +++ EK ++ +EE R L
Sbjct: 332 EFLSELQRKEEEMRQMFVNKVKETELELKEKERELHEKFEHLKRVHQEEKRKVEEKRREL 391
Query: 523 DEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLREKVDPNLW 564
+EE + N + Q L +Q+ LRK ++K + W
Sbjct: 392 EEETNAFNRRKAAVEALQSQALHATSQQPLRKDKDKKKASGW 433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,372,725
Number of Sequences: 37866
Number of extensions: 1330628
Number of successful extensions: 3185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 3059
Number of HSP's gapped (non-prelim): 69
length of query: 779
length of database: 18,247,518
effective HSP length: 110
effective length of query: 669
effective length of database: 14,082,258
effective search space: 9421030602
effective search space used: 9421030602
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.