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Search of human proteins with 115529486
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo
sapiens]
(1500 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo ... 2920 0.0
gi|55743071 ATPase, Cu++ transporting, beta polypeptide isoform ... 1539 0.0
gi|55743073 ATPase, Cu++ transporting, beta polypeptide isoform ... 814 0.0
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 122 3e-27
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 99 2e-20
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 92 5e-18
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 92 5e-18
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 91 1e-17
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 91 1e-17
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 91 1e-17
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 91 1e-17
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 87 9e-17
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 87 9e-17
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 87 9e-17
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 87 9e-17
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 87 9e-17
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 87 9e-17
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 87 9e-17
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 87 2e-16
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 87 2e-16
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 85 6e-16
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 85 6e-16
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 85 6e-16
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 79 3e-14
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 79 3e-14
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 79 4e-14
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 78 6e-14
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 78 6e-14
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 77 1e-13
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 77 1e-13
>gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo
sapiens]
Length = 1500
Score = 2920 bits (7569), Expect = 0.0
Identities = 1500/1500 (100%), Positives = 1500/1500 (100%)
Query: 1 MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPK 60
MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPK
Sbjct: 1 MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPK 60
Query: 61 TLQEAIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYP 120
TLQEAIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYP
Sbjct: 61 TLQEAIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYP 120
Query: 121 QKRTVAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGM 180
QKRTVAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGM
Sbjct: 121 QKRTVAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGM 180
Query: 181 TCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKK 240
TCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKK
Sbjct: 181 TCHSCTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKK 240
Query: 241 QPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLS 300
QPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLS
Sbjct: 241 QPKYLKLGAIDVERLKNTPVKSSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLS 300
Query: 301 ALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSS 360
ALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSS
Sbjct: 301 ALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSS 360
Query: 361 SSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVE 420
SSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVE
Sbjct: 361 SSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLANSNGTVE 420
Query: 421 YDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTNEFYTKGMTPVQD 480
YDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTNEFYTKGMTPVQD
Sbjct: 421 YDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTNEFYTKGMTPVQD 480
Query: 481 KEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPP 540
KEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPP
Sbjct: 481 KEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKAEVRYNPAVIQPP 540
Query: 541 MIAEFIRELGFGATVIENADEGDGVLELVVRGMTCASCVHKIESSLTKHRGILYCSVALA 600
MIAEFIRELGFGATVIENADEGDGVLELVVRGMTCASCVHKIESSLTKHRGILYCSVALA
Sbjct: 541 MIAEFIRELGFGATVIENADEGDGVLELVVRGMTCASCVHKIESSLTKHRGILYCSVALA 600
Query: 601 TNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFF 660
TNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFF
Sbjct: 601 TNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHLDHKREIRQWRRSFLVSLFF 660
Query: 661 CIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLLC 720
CIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLLC
Sbjct: 661 CIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINLHSSMFLERQILPGLSVMNLLSFLLC 720
Query: 721 VPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLIILLVAMYERAKVNPITF 780
VPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLIILLVAMYERAKVNPITF
Sbjct: 721 VPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATTIAFAYSLIILLVAMYERAKVNPITF 780
Query: 781 FDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVE 840
FDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVE
Sbjct: 781 FDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVE 840
Query: 841 LVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSL 900
LVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSL
Sbjct: 841 LVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSL 900
Query: 901 LICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIG 960
LICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIG
Sbjct: 901 LICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIG 960
Query: 961 FLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGA 1020
FLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGA
Sbjct: 961 FLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGA 1020
Query: 1021 QNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTA 1080
QNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTA
Sbjct: 1021 QNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTA 1080
Query: 1081 ESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDN 1140
ESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDN
Sbjct: 1081 ESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDN 1140
Query: 1141 NIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVN 1200
NIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVN
Sbjct: 1141 NIKNASLVQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVN 1200
Query: 1201 DFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKT 1260
DFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKT
Sbjct: 1201 DFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKT 1260
Query: 1261 ARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGT 1320
ARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGT
Sbjct: 1261 ARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGT 1320
Query: 1321 GTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPIAAGVFMPI 1380
GTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPIAAGVFMPI
Sbjct: 1321 GTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPIAAGVFMPI 1380
Query: 1381 GLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYESYELPARSQIGQKSPSEISVHVGI 1440
GLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYESYELPARSQIGQKSPSEISVHVGI
Sbjct: 1381 GLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTYESYELPARSQIGQKSPSEISVHVGI 1440
Query: 1441 DDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLNSVVTSEPDKHSLLVGDFREDDDTAL 1500
DDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLNSVVTSEPDKHSLLVGDFREDDDTAL
Sbjct: 1441 DDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLNSVVTSEPDKHSLLVGDFREDDDTAL 1500
>gi|55743071 ATPase, Cu++ transporting, beta polypeptide isoform a
[Homo sapiens]
Length = 1465
Score = 1539 bits (3984), Expect = 0.0
Identities = 826/1461 (56%), Positives = 1045/1461 (71%), Gaps = 66/1461 (4%)
Query: 65 AIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRT 124
A D++G++ + P + + + + I+ + KG+ +K+ ++ +
Sbjct: 38 AFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGS 97
Query: 125 VAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHS 184
V +PS+V Q+ + ++ + E K+ + S+ A E V+K++VEGMTC S
Sbjct: 98 ATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLP-AQEAVVKLRVEGMTCQS 156
Query: 185 CTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKY 244
C S+IEGK+ KLQGV R+KVSL NQEA I YQP+LI E+++ + MGF A +K +
Sbjct: 157 CVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAP 216
Query: 245 LKLGAIDVERLKNT----PVKSSEGSQQRSPSYTNDS----TATFIIDGMHCKSCVSNIE 296
L LG ID+ERL++T P+ S+ + S + + T IDGMHCKSCV NIE
Sbjct: 217 LSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE 276
Query: 297 STLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSN 356
+ L V SI VSLEN++A VKY+ S +P +L++AIEA+ PG ++VS+ E +
Sbjct: 277 ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGT 336
Query: 357 ---SPSSSSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLA 413
S SS S P N V Q T+I I GMTC SCV SIEG+IS+ GV+ I VSLA
Sbjct: 337 DHRSSSSHSPGSPPRNQV-QGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLA 395
Query: 414 NSNGTVEYDPLLTSPETLRGAIEDMGFDATL---SDTNEPL-----------VVIAQPSS 459
TV Y+P + SPE LR AIEDMGF+A++ S + PL P+S
Sbjct: 396 EGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTS 455
Query: 460 EMPLLTSTNEFYTKGMTPVQDKEEGKNSS----KCYIQVTGMTCASCVANIERNLRREEG 515
+ T + K + KC++Q+ GMTCASCV+NIERNL++E G
Sbjct: 456 VQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAG 515
Query: 516 IYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDGVLELVVRGMTC 575
+ S+LVALMAGKAE++Y+P VIQP IA+FI++LGF A V+E+ DG +EL + GMTC
Sbjct: 516 VLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTC 575
Query: 576 ASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVKKD 635
ASCVH IES LT+ GI Y SVALAT+KA +K+DPEIIGPRDII IE +GF ASL +++
Sbjct: 576 ASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIEEIGFHASLAQRN 635
Query: 636 RSASHLDHKREIRQWRRSFLVSLFFCIPVMGLMIYMMVMDHHFATLHHNQNMSKEEMINL 695
+A HLDHK EI+QW++SFL SL F IPVM LMIYM++ +
Sbjct: 636 PNAHHLDHKMEIKQWKKSFLCSLVFGIPVMALMIYMLIPSNE-----------------P 678
Query: 696 HSSMFLERQILPGLSVMNLLSFLLCVPVQFFGGWYFYIQAYKALKHKTANMDVLIVLATT 755
H SM L+ I+PGLS++NL+ F+LC VQ GGWYFY+QAYK+L+H++ANMDVLIVLAT+
Sbjct: 679 HQSMVLDHNIIPGLSILNLIFFILCTFVQLLGGWYFYVQAYKSLRHRSANMDVLIVLATS 738
Query: 756 IAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISL 815
IA+ YSL+IL+VA+ E+A+ +P+TFFDTPPMLFVFIALGRWLEH+AK KTSEALAKL+SL
Sbjct: 739 IAYVYSLVILVVAVAEKAERSPVTFFDTPPMLFVFIALGRWLEHLAKSKTSEALAKLMSL 798
Query: 816 QATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLIT 875
QATEAT+VTL DN+++ EEQV +ELVQRGDI+KVVPGGKFPVDG+V+EG++M DESLIT
Sbjct: 799 QATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLIT 858
Query: 876 GEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFAD 935
GEAMPV KKPGSTVIAGSIN +GS+LI ATHVG DTTL+QIVKLVEEAQ SKAPIQQ AD
Sbjct: 859 GEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKLVEEAQMSKAPIQQLAD 918
Query: 936 KLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITV 995
+ SGYFVPFI+ +S TL+VWIVIGF++F +V+ YFP N+ IS+TE IIRFAFQ SITV
Sbjct: 919 RFSGYFVPFIIIMSTLTLVVWIVIGFIDFGVVQRYFPNPNKHISQTEVIIRFAFQTSITV 978
Query: 996 LCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPV 1055
LCIACPCSLGLATPTAVMVGTGV AQNGILIKGG+PLEMAHK+K V+FDKTGTITHG P
Sbjct: 979 LCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIKTVMFDKTGTITHGVPR 1038
Query: 1056 VNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDTETLGTCIDFQVVP 1115
V +V +L + + K+LA+VGTAE++SEHPLG A+TKYCK+EL TETLG C DFQ VP
Sbjct: 1039 VMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEELGTETLGYCTDFQAVP 1098
Query: 1116 GCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQISNALNA 1175
GCGI CKV+N+EG+L + + AS+ + S DA
Sbjct: 1099 GCGIGCKVSNVEGILAHSERPLS-----------APASHLNEAGSLPAEKDAV------P 1141
Query: 1176 QQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCGLIAIADTVKPE 1235
Q + VLIGNREW+ RNGL I++DV+D MT+HE KG+TA+LVA+D LCG+IAIAD VK E
Sbjct: 1142 QTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAIDGVLCGMIAIADAVKQE 1201
Query: 1236 AELAIHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLPSHKVAKVKQLQEEGKR 1295
A LA+H L+SMG++VVL+TGDN KTAR+IA+QVGI KVFAEVLPSHKVAKV++LQ +GK+
Sbjct: 1202 AALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLPSHKVAKVQELQNKGKK 1261
Query: 1296 VAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRI 1355
VAMVGDG+NDSPALA A++G+AIGTGTDVAIEAADVVLIRNDLLDVVASI LS+ TV+RI
Sbjct: 1262 VAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRI 1321
Query: 1356 RINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAASSVSVVLSSLFLKLYRKPTY 1415
RIN V ALIYNLVGIPIAAGVFMPIG+VLQPWMGSAAMAASSVSVVLSSL LK Y+KP
Sbjct: 1322 RINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVSVVLSSLQLKCYKKPDL 1381
Query: 1416 ESYELPARSQIGQKSPSEISVHVGIDDTSRNSPKLGLLDRIVNYSRASINSLLSDKRSLN 1475
E YE A + + S++SVH+G+DD R+SP+ D++ S+ S++SL SDK S +
Sbjct: 1382 ERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYVSQVSLSSLTSDKPSRH 1441
Query: 1476 SVVTSEP-DKHSLLVGDFRED 1495
S + DK SLL+ E+
Sbjct: 1442 SAAADDDGDKWSLLLNGRDEE 1462
Score = 228 bits (582), Expect = 3e-59
Identities = 187/643 (29%), Positives = 281/643 (43%), Gaps = 121/643 (18%)
Query: 1 MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPK 60
+ PS V + T+ + GMTC SCV +IE +I + G+ +KVSLE+ +AT+ Y P + +
Sbjct: 51 LGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQ 110
Query: 61 TLQEAIDDMGFDAVIHN-------PDPLPVLTDTLFLTVTASLTLPW-DHIQSTLLKTKG 112
+ I DMGF+A I LP + L V I+ + K +G
Sbjct: 111 QVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQG 170
Query: 113 VTDIKIYPQKRTVAVTIIPSIVNANQ-------------IKELVPELSLDTGTLEKKSGA 159
V +K+ + +T P ++ IK V LSL +E+
Sbjct: 171 VVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQST 230
Query: 160 CEDHSMAQAGE---------------VVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKV 204
++ A + V L+++++GM C SC IE IG+L GVQ I+V
Sbjct: 231 NPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQV 290
Query: 205 SLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSE 264
SL+N+ A + Y P S +++ IEA+ P K+ D T +SS
Sbjct: 291 SLENKTAQVKYDPSCTSPVALQRAIEAL--------PPGNFKVSLPDGAEGSGTDHRSSS 342
Query: 265 ----GSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVK 320
GS R+ ST I GM C SCV +IE +S L+ V I VSL +A V
Sbjct: 343 SHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVL 402
Query: 321 YNASSVTPESLRKAIEAVSPGLYRVSITSE----------------VESTSNSPSS---- 360
YN S ++PE LR AIE + + S+ SE V++T +P+S
Sbjct: 403 YNPSVISPEELRAAIEDMG---FEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEV 459
Query: 361 -SSLQKIPLNVVSQPLT-----------QETVINIDGMTCNSCVQSIEGVISKKPGVKSI 408
++P N L Q+ + I GMTC SCV +IE + K+ GV S+
Sbjct: 460 APHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519
Query: 409 RVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTN 468
V+L ++YDP + P + I+D+GF+A + +
Sbjct: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVME---------------------- 557
Query: 469 EFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKA 528
+ + + +TGMTCASCV NIE L R GI VAL KA
Sbjct: 558 -------------DYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKA 604
Query: 529 EVRYNPAVIQPPMIAEFIRELGFGATVIE---NADEGDGVLEL 568
V+++P +I P I + I E+GF A++ + NA D +E+
Sbjct: 605 LVKFDPEIIGPRDIIKIIEEIGFHASLAQRNPNAHHLDHKMEI 647
>gi|55743073 ATPase, Cu++ transporting, beta polypeptide isoform b
[Homo sapiens]
Length = 1258
Score = 814 bits (2102), Expect = 0.0
Identities = 440/697 (63%), Positives = 523/697 (75%), Gaps = 63/697 (9%)
Query: 800 IAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVD 859
I + KTSEALAKL+SLQATEAT+VTL DN+++ EEQV +ELVQRGDI+KVVPGGKFPVD
Sbjct: 621 IIESKTSEALAKLMSLQATEATVVTLGEDNLIIREEQVPMELVQRGDIVKVVPGGKFPVD 680
Query: 860 GRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHVGADTTLSQIVKL 919
G+V+EG++M DESLITGEAMPV KKPGSTVIAGSIN +GS+LI ATHVG DTTL+QIVKL
Sbjct: 681 GKVLEGNTMADESLITGEAMPVTKKPGSTVIAGSINAHGSVLIKATHVGNDTTLAQIVKL 740
Query: 920 VEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSIS 979
VEEAQ SK P N+ IS
Sbjct: 741 VEEAQMSKNP---------------------------------------------NKHIS 755
Query: 980 RTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVK 1039
+TE IIRFAFQ SITVLCIACPCSLGLATPTAVMVGTGV AQNGILIKGG+PLEMAHK+K
Sbjct: 756 QTEVIIRFAFQTSITVLCIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHKIK 815
Query: 1040 VVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQE 1099
V+FDKTGTITHG P V +V +L + + K+LA+VGTAE++SEHPLG A+TKYCK+E
Sbjct: 816 TVMFDKTGTITHGVPRVMRVLLLGDVATLPLRKVLAVVGTAEASSEHPLGVAVTKYCKEE 875
Query: 1100 LDTETLGTCIDFQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSST 1159
L TETLG C DFQ VPGCGI CKV+N+EG+L + + AS+ +
Sbjct: 876 LGTETLGYCTDFQAVPGCGIGCKVSNVEGILAHSERPLS-----------APASHLNEAG 924
Query: 1160 SSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVD 1219
S DA Q + VLIGNREW+ RNGL I++DV+D MT+HE KG+TA+LVA+D
Sbjct: 925 SLPAEKDAV------PQTFSVLIGNREWLRRNGLTISSDVSDAMTDHEMKGQTAILVAID 978
Query: 1220 DELCGLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGITKVFAEVLP 1279
LCG+IAIAD VK EA LA+H L+SMG++VVL+TGDN KTAR+IA+QVGI KVFAEVLP
Sbjct: 979 GVLCGMIAIADAVKQEAALAVHTLQSMGVDVVLITGDNRKTARAIATQVGINKVFAEVLP 1038
Query: 1280 SHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIGTGTDVAIEAADVVLIRNDLL 1339
SHKVAKV++LQ +GK+VAMVGDG+NDSPALA A++G+AIGTGTDVAIEAADVVLIRNDLL
Sbjct: 1039 SHKVAKVQELQNKGKKVAMVGDGVNDSPALAQADMGVAIGTGTDVAIEAADVVLIRNDLL 1098
Query: 1340 DVVASIDLSRETVKRIRINFVFALIYNLVGIPIAAGVFMPIGLVLQPWMGSAAMAASSVS 1399
DVVASI LS+ TV+RIRIN V ALIYNLVGIPIAAGVFMPIG+VLQPWMGSAAMAASSVS
Sbjct: 1099 DVVASIHLSKRTVRRIRINLVLALIYNLVGIPIAAGVFMPIGIVLQPWMGSAAMAASSVS 1158
Query: 1400 VVLSSLFLKLYRKPTYESYELPARSQIGQKSPSEISVHVGIDDTSRNSPKLGLLDRIVNY 1459
VVLSSL LK Y+KP E YE A + + S++SVH+G+DD R+SP+ D++
Sbjct: 1159 VVLSSLQLKCYKKPDLERYEAQAHGHMKPLTASQVSVHIGMDDRWRDSPRATPWDQVSYV 1218
Query: 1460 SRASINSLLSDKRSLNSVVTSEP-DKHSLLVGDFRED 1495
S+ S++SL SDK S +S + DK SLL+ E+
Sbjct: 1219 SQVSLSSLTSDKPSRHSAAADDDGDKWSLLLNGRDEE 1255
Score = 436 bits (1120), Expect = e-121
Identities = 257/594 (43%), Positives = 354/594 (59%), Gaps = 31/594 (5%)
Query: 65 AIDDMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRT 124
A D++G++ + P + + + + I+ + KG+ +K+ ++ +
Sbjct: 38 AFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGS 97
Query: 125 VAVTIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHS 184
V +PS+V Q+ + ++ + E K+ + S+ A E V+K++VEGMTC S
Sbjct: 98 ATVKYVPSVVCLQQVCHQIGDMGFEASIAEGKAASWPSRSLP-AQEAVVKLRVEGMTCQS 156
Query: 185 CTSTIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKY 244
C S+IEGK+ KLQGV R+KVSL NQEA I YQP+LI E+++ + MGF A +K +
Sbjct: 157 CVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAP 216
Query: 245 LKLGAIDVERLKNT----PVKSSEGSQQRSPSYTNDS----TATFIIDGMHCKSCVSNIE 296
L LG ID+ERL++T P+ S+ + S + + T IDGMHCKSCV NIE
Sbjct: 217 LSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIE 276
Query: 297 STLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSN 356
+ L V SI VSLEN++A VKY+ S +P +L++AIEA+ PG ++VS+ E +
Sbjct: 277 ENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGT 336
Query: 357 ---SPSSSSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLA 413
S SS S P N V Q T+I I GMTC SCV SIEG+IS+ GV+ I VSLA
Sbjct: 337 DHRSSSSHSPGSPPRNQV-QGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLA 395
Query: 414 NSNGTVEYDPLLTSPETLRGAIEDMGFDATL---SDTNEPL-----------VVIAQPSS 459
TV Y+P + SPE LR AIEDMGF+A++ S + PL P+S
Sbjct: 396 EGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTS 455
Query: 460 EMPLLTSTNEFYTKGMTPVQDKEEGKNSS----KCYIQVTGMTCASCVANIERNLRREEG 515
+ T + K + KC++Q+ GMTCASCV+NIERNL++E G
Sbjct: 456 VQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAG 515
Query: 516 IYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDGVLELVVRGMTC 575
+ S+LVALMAGKAE++Y+P VIQP IA+FI++LGF A V+E+ DG +EL + GMTC
Sbjct: 516 VLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVMEDYAGSDGNIELTITGMTC 575
Query: 576 ASCVHKIESSLTKHRGILYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEA 629
ASCVH IES LT+ GI Y SVALAT+KA +K+DPEIIGPRDII IES EA
Sbjct: 576 ASCVHNIESKLTRTNGITYASVALATSKALVKFDPEIIGPRDIIKIIESKTSEA 629
Score = 227 bits (578), Expect = 7e-59
Identities = 180/581 (30%), Positives = 274/581 (47%), Gaps = 126/581 (21%)
Query: 140 KELVPELSLDTGTLE---KKSGACED-------HSMAQAGEVVLK-MKVEGMTCHSCTST 188
++++ +LSL T E KKS A ++ + + +V +++ GMTC SC +
Sbjct: 16 RKILSKLSLPTRAWEPAMKKSFAFDNVGYEGGLDGLGPSSQVATSTVRILGMTCQSCVKS 75
Query: 189 IEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLG 248
IE +I L+G+ +KVSL+ AT+ Y P ++ ++++ QI MGF A +
Sbjct: 76 IEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQQVCHQIGDMGFEASI---------- 125
Query: 249 AIDVERLKNTPVKSSEGSQQRSPSYT---NDSTATFIIDGMHCKSCVSNIESTLSALQYV 305
+EG PS + ++ ++GM C+SCVS+IE + LQ V
Sbjct: 126 --------------AEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQGV 171
Query: 306 SSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVESTSNSPSS----- 360
+ VSL N+ A++ Y + PE LR + + + +I S+V S P
Sbjct: 172 VRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMG---FEAAIKSKVAPLSLGPIDIERLQ 228
Query: 361 SSLQKIPLNVVSQPLTQ-ETV-----------INIDGMTCNSCVQSIEGVISKKPGVKSI 408
S+ K PL+ +Q ET+ + IDGM C SCV +IE I + GV+SI
Sbjct: 229 STNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSI 288
Query: 409 RVSLANSNGTVEYDPLLTSPETLRGAIEDM---GFDATLSDTNEPLVVIAQPSSEMPLLT 465
+VSL N V+YDP TSP L+ AIE + F +L D E + SS
Sbjct: 289 QVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTDHRSSSS----- 343
Query: 466 STNEFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMA 525
++ G +P +++ +G S I + GMTCASCV +IE + + EG+ I V+L
Sbjct: 344 -----HSPG-SPPRNQVQG-TCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAE 396
Query: 526 GKAEVRYNPAVIQPPMIAEFIRELGFGATVIE---------NADEGDGVLE--------- 567
G A V YNP+VI P + I ++GF A+V+ N G+ +++
Sbjct: 397 GTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSV 456
Query: 568 -----------------------------------LVVRGMTCASCVHKIESSLTKHRGI 592
L ++GMTCASCV IE +L K G+
Sbjct: 457 QEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGV 516
Query: 593 LYCSVALATNKAHIKYDPEIIGPRDIIHTIESLGFEASLVK 633
L VAL KA IKYDPE+I P +I I+ LGFEA++++
Sbjct: 517 LSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVME 557
Score = 218 bits (556), Expect = 3e-56
Identities = 179/618 (28%), Positives = 267/618 (43%), Gaps = 118/618 (19%)
Query: 1 MDPSMGVNSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPK 60
+ PS V + T+ + GMTC SCV +IE +I + G+ +KVSLE+ +AT+ Y P + +
Sbjct: 51 LGPSSQVATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVCLQ 110
Query: 61 TLQEAIDDMGFDAVIHN-------PDPLPVLTDTLFLTVTASLTLPW-DHIQSTLLKTKG 112
+ I DMGF+A I LP + L V I+ + K +G
Sbjct: 111 QVCHQIGDMGFEASIAEGKAASWPSRSLPAQEAVVKLRVEGMTCQSCVSSIEGKVRKLQG 170
Query: 113 VTDIKIYPQKRTVAVTIIPSIVNANQ-------------IKELVPELSLDTGTLEKKSGA 159
V +K+ + +T P ++ IK V LSL +E+
Sbjct: 171 VVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLGPIDIERLQST 230
Query: 160 CEDHSMAQAGE---------------VVLKMKVEGMTCHSCTSTIEGKIGKLQGVQRIKV 204
++ A + V L+++++GM C SC IE IG+L GVQ I+V
Sbjct: 231 NPKRPLSSANQNFNNSETLGHQGSHVVTLQLRIDGMHCKSCVLNIEENIGQLLGVQSIQV 290
Query: 205 SLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKLGAIDVERLKNTPVKSSE 264
SL+N+ A + Y P S +++ IEA+ P K+ D T +SS
Sbjct: 291 SLENKTAQVKYDPSCTSPVALQRAIEAL--------PPGNFKVSLPDGAEGSGTDHRSSS 342
Query: 265 ----GSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVK 320
GS R+ ST I GM C SCV +IE +S L+ V I VSL +A V
Sbjct: 343 SHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVL 402
Query: 321 YNASSVTPESLRKAIEAVSPGLYRVSITSE----------------VESTSNSPSS---- 360
YN S ++PE LR AIE + + S+ SE V++T +P+S
Sbjct: 403 YNPSVISPEELRAAIEDMG---FEASVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEV 459
Query: 361 -SSLQKIPLNVVSQPLT-----------QETVINIDGMTCNSCVQSIEGVISKKPGVKSI 408
++P N L Q+ + I GMTC SCV +IE + K+ GV S+
Sbjct: 460 APHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVSNIERNLQKEAGVLSV 519
Query: 409 RVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPLVVIAQPSSEMPLLTSTN 468
V+L ++YDP + P + I+D+GF+A + +
Sbjct: 520 LVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAVME---------------------- 557
Query: 469 EFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIERNLRREEGIYSILVALMAGKA 528
+ + + +TGMTCASCV NIE L R GI VAL KA
Sbjct: 558 -------------DYAGSDGNIELTITGMTCASCVHNIESKLTRTNGITYASVALATSKA 604
Query: 529 EVRYNPAVIQPPMIAEFI 546
V+++P +I P I + I
Sbjct: 605 LVKFDPEIIGPRDIIKII 622
Score = 184 bits (468), Expect = 4e-46
Identities = 130/399 (32%), Positives = 192/399 (48%), Gaps = 54/399 (13%)
Query: 277 STATFIIDGMHCKSCVSNIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIE 336
+T+T I GM C+SCV +IE +S L+ + S+ VSLE SA VKY S V L++
Sbjct: 58 ATSTVRILGMTCQSCVKSIEDRISNLKGIISMKVSLEQGSATVKYVPSVVC---LQQVCH 114
Query: 337 AVSPGLYRVSITSEVESTSNSPSSSSLQKIPLNVVSQPLTQETVIN--IDGMTCNSCVQS 394
+ + SI E + S S SL QE V+ ++GMTC SCV S
Sbjct: 115 QIGDMGFEASIA---EGKAASWPSRSLP-----------AQEAVVKLRVEGMTCQSCVSS 160
Query: 395 IEGVISKKPGVKSIRVSLANSNGTVEYDPLLTSPETLRGAIEDMGFDATLSDTNEPL--- 451
IEG + K GV ++VSL+N + Y P L PE LR + DMGF+A + PL
Sbjct: 161 IEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDMGFEAAIKSKVAPLSLG 220
Query: 452 ---VVIAQPSSEMPLLTSTNEFYTKGMTPVQDKEEGKNSSKCYIQVTGMTCASCVANIER 508
+ Q ++ L+S N+ + T +G + +++ GM C SCV NIE
Sbjct: 221 PIDIERLQSTNPKRPLSSANQNFNNSETL---GHQGSHVVTLQLRIDGMHCKSCVLNIEE 277
Query: 509 NLRREEGIYSILVALMAGKAEVRYNPAVIQPPMIAEFIRELGFGATVIENADEGDG---- 564
N+ + G+ SI V+L A+V+Y+P+ P + I L G + D +G
Sbjct: 278 NIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFKVSLPDGAEGSGTD 337
Query: 565 ----------------------VLELVVRGMTCASCVHKIESSLTKHRGILYCSVALATN 602
+ + GMTCASCVH IE +++ G+ SV+LA
Sbjct: 338 HRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEG 397
Query: 603 KAHIKYDPEIIGPRDIIHTIESLGFEASLVKKDRSASHL 641
A + Y+P +I P ++ IE +GFEAS+V + S + L
Sbjct: 398 TATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPL 436
Score = 160 bits (405), Expect = 9e-39
Identities = 140/509 (27%), Positives = 215/509 (42%), Gaps = 100/509 (19%)
Query: 10 VTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAIDDM 69
V + VEGMTC SCV +IE ++ K+ GV +KVSL + A I Y P L P+ L++ ++DM
Sbjct: 145 VKLRVEGMTCQSCVSSIEGKVRKLQGVVRVKVSLSNQEAVITYQPYLIQPEDLRDHVNDM 204
Query: 70 GFDAVIHNP-DPL---PVLTDTLFLT--------------------------VTASLTLP 99
GF+A I + PL P+ + L T VT L +
Sbjct: 205 GFEAAIKSKVAPLSLGPIDIERLQSTNPKRPLSSANQNFNNSETLGHQGSHVVTLQLRID 264
Query: 100 WDHIQSTLLKTK-------GVTDIKIYPQKRTVAVTIIPSIVNANQIK---ELVPELSLD 149
H +S +L + GV I++ + +T V PS + ++ E +P +
Sbjct: 265 GMHCKSCVLNIEENIGQLLGVQSIQVSLENKTAQVKYDPSCTSPVALQRAIEALPPGNFK 324
Query: 150 TGTLEKKSGACEDH-------------SMAQAGEVVLKMKVEGMTCHSCTSTIEGKIGKL 196
+ G+ DH + Q + + GMTC SC +IEG I +L
Sbjct: 325 VSLPDGAEGSGTDHRSSSSHSPGSPPRNQVQGTCSTTLIAIAGMTCASCVHSIEGMISQL 384
Query: 197 QGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYL------KLGAI 250
+GVQ+I VSL AT++Y P +IS EE++ IE MGF A V + G
Sbjct: 385 EGVQQISVSLAEGTATVLYNPSVISPEELRAAIEDMGFEASVVSESCSTNPLGNHSAGNS 444
Query: 251 DVERLKNTPVKSSEGSQQ--------------RSPSYTN---DSTATFIIDGMHCKSCVS 293
V+ TP E + +SP T I GM C SCVS
Sbjct: 445 MVQTTDGTPTSVQEVAPHTGRLPANHAPDILAKSPQSTRAVAPQKCFLQIKGMTCASCVS 504
Query: 294 NIESTLSALQYVSSIVVSLENRSAIVKYNASSVTPESLRKAIEAVSPGLYRVSITSEVES 353
NIE L V S++V+L A +KY+ + P + + I+ + + ++ +
Sbjct: 505 NIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLG---FEAAVMEDYAG 561
Query: 354 TSNSPSSSSLQKIPLNVVSQPLTQETVINIDGMTCNSCVQSIEGVISKKPGVKSIRVSLA 413
+ + + I GMTC SCV +IE +++ G+ V+LA
Sbjct: 562 SDGN---------------------IELTITGMTCASCVHNIESKLTRTNGITYASVALA 600
Query: 414 NSNGTVEYDPLLTSPETLRGAIEDMGFDA 442
S V++DP + P + IE +A
Sbjct: 601 TSKALVKFDPEIIGPRDIIKIIESKTSEA 629
Score = 115 bits (289), Expect = 2e-25
Identities = 108/428 (25%), Positives = 188/428 (43%), Gaps = 81/428 (18%)
Query: 8 NSVTISVEGMTCNSCVWTIEQQIGKVNGVHHIKVSLEEKNATIIYDPKLQTPKTLQEAID 67
++ I++ GMTC SCV +IE I ++ GV I VSL E AT++Y+P + +P+ L+ AI+
Sbjct: 359 STTLIAIAGMTCASCVHSIEGMISQLEGVQQISVSLAEGTATVLYNPSVISPEELRAAIE 418
Query: 68 DMGFDAVIHNPDPLPVLTDTLFLTVTASLTLPWDHIQSTLLKTKGVTDIKIYPQKRTVAV 127
DMGF+A V++++ + + +Q+T V ++ + +
Sbjct: 419 DMGFEA--------SVVSESCSTNPLGNHSAGNSMVQTTDGTPTSVQEVAPHTGR----- 465
Query: 128 TIIPSIVNANQIKELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTCHSCTS 187
+ AN +++ + T + + ++++GMTC SC S
Sbjct: 466 ------LPANHAPDILAKSPQSTRAVAPQK---------------CFLQIKGMTCASCVS 504
Query: 188 TIEGKIGKLQGVQRIKVSLDNQEATIVYQPHLISVEEMKKQIEAMGFPAFVKKQPKYLKL 247
IE + K GV + V+L +A I Y P +I E+ + I+ +GF A V
Sbjct: 505 NIERNLQKEAGVLSVLVALMAGKAEIKYDPEVIQPLEIAQFIQDLGFEAAV--------- 555
Query: 248 GAIDVERLKNTPVKSSEGSQQRSPSYTNDSTATFIIDGMHCKSCVSNIESTLSALQYVSS 307
++ GS D I GM C SCV NIES L+ ++
Sbjct: 556 ------------MEDYAGS---------DGNIELTITGMTCASCVHNIESKLTRTNGITY 594
Query: 308 IVVSLENRSAIVKYNASSVTPESLRKAIEA-VSPGLYRVSITSEVESTSNSPSSSSL--- 363
V+L A+VK++ + P + K IE+ S L ++ E+T + +L
Sbjct: 595 ASVALATSKALVKFDPEIIGPRDIIKIIESKTSEALAKLMSLQATEATVVTLGEDNLIIR 654
Query: 364 -QKIPLNVVSQPLTQETV----INIDGMTCNSCVQSIEGVI-------SKKPGVKSIRVS 411
+++P+ +V + + V +DG + E +I +KKPG I S
Sbjct: 655 EEQVPMELVQRGDIVKVVPGGKFPVDGKVLEGNTMADESLITGEAMPVTKKPGSTVIAGS 714
Query: 412 LANSNGTV 419
+ N++G+V
Sbjct: 715 I-NAHGSV 721
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 122 bits (305), Expect = 3e-27
Identities = 142/627 (22%), Positives = 260/627 (41%), Gaps = 109/627 (17%)
Query: 800 IAKGKTSEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVD 859
I + ++ ++L +L + E + LL+ E V GD++ + G + P D
Sbjct: 150 IQEYRSEKSLEELTKMVPPECNCLREGKLQHLLARELVP------GDVVSLSIGDRIPAD 203
Query: 860 GRVIEGHSM-VDESLITGEAMPVAKKPGSTVIAGSINQNGSLLICATHV----------- 907
R+ E + VDES TGEA P +K G + +++ T V
Sbjct: 204 IRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGTLVQYGRGQGVVIG 263
Query: 908 -GADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIV-FVSIATLLVWIVIGFLNFE 965
G + ++ K+++ +T K P+Q+ D+L F + + L+ W
Sbjct: 264 TGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLTLFSFGIIGLIMLIGW--------- 314
Query: 966 IVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGIL 1025
S+ + ++ F +++ A P L + +++G A+ ++
Sbjct: 315 -------------SQGKQLLSM-FTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVI 360
Query: 1026 IKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISHHKILAIVGTAESNSE 1085
+K +E V+ DKTGT+T V Q+ ++ + A V + +
Sbjct: 361 VKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQL--------VTSDGLRAEVSGVGYDGQ 412
Query: 1086 HPLGTAITKYCKQELDTETLGTCIDFQVVPGCGISCKVTNI----EGLLHKNNWNIEDNN 1141
+ +K +E ++G ++ V + K + EG L ++ ++
Sbjct: 413 GTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVMGQPTEGALMALAMKMDLSD 472
Query: 1142 IKNASL--VQIDASNEQSSTSSSMIIDAQISNALNAQQYKVLIGNREWMIRNGLVINN-- 1197
IKN+ + +I S+EQ + + + + + + G E +IR + NN
Sbjct: 473 IKNSYIRKKEIPFSSEQKWMAVKCSLKTE-----DQEDIYFMKGALEEVIRYCTMYNNGG 527
Query: 1198 -------DVNDFMTEHERK----GRTAVLVAVDDEL-----CGLIAIADTVKPEAELAIH 1241
F + E++ G + +A EL GL+ I D + + A+
Sbjct: 528 IPLPLTPQQRSFCLQEEKRMGSLGLRVLALASGPELGRLTFLGLVGIIDPPRVGVKEAVQ 587
Query: 1242 ILKSMGLEVVLMTGDNSKTARSI---------------------------ASQVGITKVF 1274
+L G+ V ++TGD +TA +I A +VG VF
Sbjct: 588 VLSESGVSVKMITGDALETALAIGRNIGLCNGKLQAMSGEEVDSVEKGELADRVGKVSVF 647
Query: 1275 AEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIG-TGTDVAIEAADVVL 1333
P HK+ +K LQE G VAM GDG+ND+ AL A++GIA+G TGTDV+ EAA+++L
Sbjct: 648 FRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANMIL 707
Query: 1334 IRNDLLDVVASIDLSRETVKRIRINFV 1360
+ +D ++ +++ + I+ NFV
Sbjct: 708 VDDDFSAIMNAVEEGKGIFYNIK-NFV 733
>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
Length = 1020
Score = 99.4 bits (246), Expect = 2e-20
Identities = 140/656 (21%), Positives = 253/656 (38%), Gaps = 138/656 (21%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKKPGST------ 888
Q++ E V GD+++V G + P D R+I H VD S +TGE+ P + P T
Sbjct: 177 QINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLE 236
Query: 889 ------VIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFV 942
+ ++ AT G T + +I L + + PI +
Sbjct: 237 TRNICFFSTNCVEGTARGIVIAT--GDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLIT 294
Query: 943 PFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPC 1002
VF+ ++ ++ +++G+ S E +I I ++ P
Sbjct: 295 GVAVFLGVSFFVLSLILGY-----------------SWLEAVIFL-----IGIIVANVPE 332
Query: 1003 SLGLATPTAVMVGTGVG-AQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVV----- 1056
L LAT T + T A+ L+K E +E + DKTGT+T V
Sbjct: 333 GL-LATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWF 391
Query: 1057 -NQVKVL--TESNRISHHKILAIVGTAESNSEHPLGTAITKYCKQELDT---ETLGTCID 1110
NQ+ TE + + TA S A+ K ++ + +T G +
Sbjct: 392 DNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASE 451
Query: 1111 FQVVPGCGISCKVTNIEGLLHKNNWNIEDNNIKNASLVQIDASNEQSSTSSSMIIDAQIS 1170
++ +SC + N + + + + Q+ + S S +++
Sbjct: 452 SALLKCIELSCGSVR---KMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAP 508
Query: 1171 NALNAQQYKVLIGNRE--------------WMIRNGLVINNDVNDFMTEHERKGR----- 1211
+ + +L+ +E +M GL V F + G+
Sbjct: 509 ERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGL--GERVLGFCQLNLPSGKFPRGF 566
Query: 1212 ---TAVLVAVDDELC--GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARS--- 1263
T L ++LC GL+++ D + A+ +S G++V+++TGD+ TA++
Sbjct: 567 KFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAK 626
Query: 1264 --------------IASQVGITK------------------------------------V 1273
IA+++ I V
Sbjct: 627 GVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIV 686
Query: 1274 FAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIG-TGTDVAIEAADVV 1332
FA P K+ V+ Q +G VA+ GDG+NDSPAL A++GIA+G +G+DV+ +AAD++
Sbjct: 687 FARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMI 746
Query: 1333 LIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIP-----IAAGVFMPIGLV 1383
L+ ++ +V ++ R ++ + + L N+ I I A + +P+G V
Sbjct: 747 LLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTV 802
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 91.7 bits (226), Expect = 5e-18
Identities = 157/685 (22%), Positives = 258/685 (37%), Gaps = 165/685 (24%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKK--------PG 886
Q+ V + GDI +V G P DG +I+G+ + +DES +TGE+ V K G
Sbjct: 204 QIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSG 263
Query: 887 STVIAGS---------INQNGSLLICATHVGADTTLSQIVKLVEEAQT---------SKA 928
+ V+ GS +N ++ G + + K E+ +KA
Sbjct: 264 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQDGAIENRNKA 323
Query: 929 PIQQFA------------------DK------------LSGYFVPFIVFVSIATLL---V 955
Q A DK L G V + A LL +
Sbjct: 324 KAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAI 383
Query: 956 WIVIGFLNFEIVETYFPGYNRSISRTETI-----IRFAFQASITVLCIACPCSLGLATPT 1010
++I L F +++T++ ++ I ++F F +TVL +A P L LA
Sbjct: 384 TVIILVLYF-VIDTFWVQKRPWLAECTPIYIQYFVKF-FIIGVTVLVVAVPEGLPLAVTI 441
Query: 1011 AVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISH 1070
++ ++ L++ + E + DKTGT+T +N++ V+ H
Sbjct: 442 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT-----MNRMTVVQAYINEKH 496
Query: 1071 HKILAIVGTAESNSEHPLGTAITKYC---KQELDTETLGTCIDFQVVPGCGISCKVTN-- 1125
+K + N L T I+ C + L E G G+ V N
Sbjct: 497 YKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEG-----------GLPRHVGNKT 545
Query: 1126 ---IEGLLHKNNWNIED--NNIKNASLVQIDASNE---------QSSTSSSMIIDAQISN 1171
+ GLL + +D N I +L ++ N ++S S I S
Sbjct: 546 ECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASE 605
Query: 1172 ALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCG------- 1224
+ + +K+L N E + ++ V + +G + +A D G
Sbjct: 606 IILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWD 665
Query: 1225 -------------LIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT 1271
++ I D V+PE AI + G+ V ++TGDN TAR+IA++ GI
Sbjct: 666 NENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGIL 725
Query: 1272 -------------------------------------KVFAEVLPSHKVAKVKQL----- 1289
+V A P+ K VK +
Sbjct: 726 HPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTV 785
Query: 1290 QEEGKRVAMVGDGINDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLS 1348
++ + VA+ GDG ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++
Sbjct: 786 SDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWG 845
Query: 1349 RETVKRIRINFVFALIYNLVGIPIA 1373
R I F L N+V + +A
Sbjct: 846 RNVYDSISKFLQFQLTVNVVAVIVA 870
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 91.7 bits (226), Expect = 5e-18
Identities = 157/685 (22%), Positives = 258/685 (37%), Gaps = 165/685 (24%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKK--------PG 886
Q+ V + GDI +V G P DG +I+G+ + +DES +TGE+ V K G
Sbjct: 204 QIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPLLLSG 263
Query: 887 STVIAGS---------INQNGSLLICATHVGADTTLSQIVKLVEEAQT---------SKA 928
+ V+ GS +N ++ G + + K E+ +KA
Sbjct: 264 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQDGAIENRNKA 323
Query: 929 PIQQFA------------------DK------------LSGYFVPFIVFVSIATLL---V 955
Q A DK L G V + A LL +
Sbjct: 324 KAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAI 383
Query: 956 WIVIGFLNFEIVETYFPGYNRSISRTETI-----IRFAFQASITVLCIACPCSLGLATPT 1010
++I L F +++T++ ++ I ++F F +TVL +A P L LA
Sbjct: 384 TVIILVLYF-VIDTFWVQKRPWLAECTPIYIQYFVKF-FIIGVTVLVVAVPEGLPLAVTI 441
Query: 1011 AVMVGTGVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESNRISH 1070
++ ++ L++ + E + DKTGT+T +N++ V+ H
Sbjct: 442 SLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT-----MNRMTVVQAYINEKH 496
Query: 1071 HKILAIVGTAESNSEHPLGTAITKYC---KQELDTETLGTCIDFQVVPGCGISCKVTN-- 1125
+K + N L T I+ C + L E G G+ V N
Sbjct: 497 YKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEG-----------GLPRHVGNKT 545
Query: 1126 ---IEGLLHKNNWNIED--NNIKNASLVQIDASNE---------QSSTSSSMIIDAQISN 1171
+ GLL + +D N I +L ++ N ++S S I S
Sbjct: 546 ECALLGLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASE 605
Query: 1172 ALNAQQYKVLIGNREWMIRNGLVINNDVNDFMTEHERKGRTAVLVAVDDELCG------- 1224
+ + +K+L N E + ++ V + +G + +A D G
Sbjct: 606 IILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWD 665
Query: 1225 -------------LIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT 1271
++ I D V+PE AI + G+ V ++TGDN TAR+IA++ GI
Sbjct: 666 NENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGIL 725
Query: 1272 -------------------------------------KVFAEVLPSHKVAKVKQL----- 1289
+V A P+ K VK +
Sbjct: 726 HPGEDFLCLEGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTV 785
Query: 1290 QEEGKRVAMVGDGINDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLS 1348
++ + VA+ GDG ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++
Sbjct: 786 SDQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWG 845
Query: 1349 RETVKRIRINFVFALIYNLVGIPIA 1373
R I F L N+V + +A
Sbjct: 846 RNVYDSISKFLQFQLTVNVVAVIVA 870
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
Length = 939
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/165 (33%), Positives = 90/165 (54%), Gaps = 29/165 (17%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
GL+ I D + + A+ L + G+ + ++TGD+ +TA +IAS++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1271 --------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGI 1316
VF P HK+ +K LQ+ G VAM GDG+ND+ AL A++G+
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1317 AIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFV 1360
A+G TGTDV EAAD++L+ +D ++++I+ + I+ NFV
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK-NFV 703
Score = 48.5 bits (114), Expect = 5e-05
Identities = 71/320 (22%), Positives = 130/320 (40%), Gaps = 51/320 (15%)
Query: 758 FAYSLIILLVAMYERAKVNPITF-FDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQ 816
F LI+LL+A A ++ + FD + V I + + + + ++ ++L +L L
Sbjct: 79 FKNPLIMLLLAS---AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLV 135
Query: 817 ATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLIT 875
E V L+ + V GD + + G + P D R+ E + +DES +T
Sbjct: 136 PPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLRLFEAVDLSIDESSLT 189
Query: 876 GEAMPVAK----KPGST----VIAGSINQNGSLLICATH------VGADTTLSQIVKLVE 921
GE P +K +P +T +I G+L+ C G ++ ++ K+++
Sbjct: 190 GETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQ 249
Query: 922 EAQTSKAPIQQFADKLSGYFVPFIVF--VSIATLLVWIVIGFLNFEIVETYFPGYNRSIS 979
+ K P+Q+ D L G + F F + I L+ W+ L +I+E
Sbjct: 250 AEEAPKTPLQKSMDLL-GKQLSFYSFGIIGIIMLVGWL----LGKDILEM---------- 294
Query: 980 RTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVK 1039
F S+++ A P L + + +G + ++K +E
Sbjct: 295 ---------FTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCN 345
Query: 1040 VVVFDKTGTITHGTPVVNQV 1059
V+ DKTGT+T V +
Sbjct: 346 VICSDKTGTLTKNEMTVTHI 365
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
Length = 949
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/165 (33%), Positives = 90/165 (54%), Gaps = 29/165 (17%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
GL+ I D + + A+ L + G+ + ++TGD+ +TA +IAS++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1271 --------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGI 1316
VF P HK+ +K LQ+ G VAM GDG+ND+ AL A++G+
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1317 AIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFV 1360
A+G TGTDV EAAD++L+ +D ++++I+ + I+ NFV
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK-NFV 703
Score = 48.5 bits (114), Expect = 5e-05
Identities = 71/320 (22%), Positives = 130/320 (40%), Gaps = 51/320 (15%)
Query: 758 FAYSLIILLVAMYERAKVNPITF-FDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQ 816
F LI+LL+A A ++ + FD + V I + + + + ++ ++L +L L
Sbjct: 79 FKNPLIMLLLAS---AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLV 135
Query: 817 ATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLIT 875
E V L+ + V GD + + G + P D R+ E + +DES +T
Sbjct: 136 PPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLRLFEAVDLSIDESSLT 189
Query: 876 GEAMPVAK----KPGST----VIAGSINQNGSLLICATH------VGADTTLSQIVKLVE 921
GE P +K +P +T +I G+L+ C G ++ ++ K+++
Sbjct: 190 GETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQ 249
Query: 922 EAQTSKAPIQQFADKLSGYFVPFIVF--VSIATLLVWIVIGFLNFEIVETYFPGYNRSIS 979
+ K P+Q+ D L G + F F + I L+ W+ L +I+E
Sbjct: 250 AEEAPKTPLQKSMDLL-GKQLSFYSFGIIGIIMLVGWL----LGKDILEM---------- 294
Query: 980 RTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVK 1039
F S+++ A P L + + +G + ++K +E
Sbjct: 295 ---------FTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCN 345
Query: 1040 VVVFDKTGTITHGTPVVNQV 1059
V+ DKTGT+T V +
Sbjct: 346 VICSDKTGTLTKNEMTVTHI 365
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
Length = 888
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/165 (33%), Positives = 90/165 (54%), Gaps = 29/165 (17%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
GL+ I D + + A+ L + G+ + ++TGD+ +TA +IAS++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1271 --------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGI 1316
VF P HK+ +K LQ+ G VAM GDG+ND+ AL A++G+
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1317 AIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFV 1360
A+G TGTDV EAAD++L+ +D ++++I+ + I+ NFV
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK-NFV 703
Score = 48.5 bits (114), Expect = 5e-05
Identities = 71/320 (22%), Positives = 130/320 (40%), Gaps = 51/320 (15%)
Query: 758 FAYSLIILLVAMYERAKVNPITF-FDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQ 816
F LI+LL+A A ++ + FD + V I + + + + ++ ++L +L L
Sbjct: 79 FKNPLIMLLLAS---AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLV 135
Query: 817 ATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLIT 875
E V L+ + V GD + + G + P D R+ E + +DES +T
Sbjct: 136 PPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLRLFEAVDLSIDESSLT 189
Query: 876 GEAMPVAK----KPGST----VIAGSINQNGSLLICATH------VGADTTLSQIVKLVE 921
GE P +K +P +T +I G+L+ C G ++ ++ K+++
Sbjct: 190 GETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQ 249
Query: 922 EAQTSKAPIQQFADKLSGYFVPFIVF--VSIATLLVWIVIGFLNFEIVETYFPGYNRSIS 979
+ K P+Q+ D L G + F F + I L+ W+ L +I+E
Sbjct: 250 AEEAPKTPLQKSMDLL-GKQLSFYSFGIIGIIMLVGWL----LGKDILEM---------- 294
Query: 980 RTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVK 1039
F S+++ A P L + + +G + ++K +E
Sbjct: 295 ---------FTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCN 345
Query: 1040 VVVFDKTGTITHGTPVVNQV 1059
V+ DKTGT+T V +
Sbjct: 346 VICSDKTGTLTKNEMTVTHI 365
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
Length = 919
Score = 90.5 bits (223), Expect = 1e-17
Identities = 55/165 (33%), Positives = 90/165 (54%), Gaps = 29/165 (17%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
GL+ I D + + A+ L + G+ + ++TGD+ +TA +IAS++G+
Sbjct: 540 GLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQSVSGEEI 599
Query: 1271 --------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMANVGI 1316
VF P HK+ +K LQ+ G VAM GDG+ND+ AL A++G+
Sbjct: 600 DAMDVQQLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGV 659
Query: 1317 AIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFV 1360
A+G TGTDV EAAD++L+ +D ++++I+ + I+ NFV
Sbjct: 660 AMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIK-NFV 703
Score = 48.5 bits (114), Expect = 5e-05
Identities = 71/320 (22%), Positives = 130/320 (40%), Gaps = 51/320 (15%)
Query: 758 FAYSLIILLVAMYERAKVNPITF-FDTPPMLFVFIALGRWLEHIAKGKTSEALAKLISLQ 816
F LI+LL+A A ++ + FD + V I + + + + ++ ++L +L L
Sbjct: 79 FKNPLIMLLLAS---AVISVLMHQFDDAVSITVAILIVVTVAFVQEYRSEKSLEELSKLV 135
Query: 817 ATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLIT 875
E V L+ + V GD + + G + P D R+ E + +DES +T
Sbjct: 136 PPECHCVREGKLEHTLARDLVP------GDTVCLSVGDRVPADLRLFEAVDLSIDESSLT 189
Query: 876 GEAMPVAK----KPGST----VIAGSINQNGSLLICATH------VGADTTLSQIVKLVE 921
GE P +K +P +T +I G+L+ C G ++ ++ K+++
Sbjct: 190 GETTPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQ 249
Query: 922 EAQTSKAPIQQFADKLSGYFVPFIVF--VSIATLLVWIVIGFLNFEIVETYFPGYNRSIS 979
+ K P+Q+ D L G + F F + I L+ W+ L +I+E
Sbjct: 250 AEEAPKTPLQKSMDLL-GKQLSFYSFGIIGIIMLVGWL----LGKDILEM---------- 294
Query: 980 RTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPLEMAHKVK 1039
F S+++ A P L + + +G + ++K +E
Sbjct: 295 ---------FTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCN 345
Query: 1040 VVVFDKTGTITHGTPVVNQV 1059
V+ DKTGT+T V +
Sbjct: 346 VICSDKTGTLTKNEMTVTHI 365
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D +PE I G+ VV++TGDN TA +I ++GI
Sbjct: 595 GCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V P+HK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA AA++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAILGL 783
Score = 68.9 bits (167), Expect = 3e-11
Identities = 72/334 (21%), Positives = 138/334 (41%), Gaps = 39/334 (11%)
Query: 752 LATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKTSEA 808
L I +L+ ++A +E + F + ++ + +A +G W E A+ A
Sbjct: 60 LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----A 115
Query: 809 LAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM 868
+ L + ++ D + +++ + GDI++V G K P D R+IE S
Sbjct: 116 IEALKEYEPEMGKVIRSDRKGV----QRIRARDIVPGDIVEVAVGDKVPADLRLIEIKST 171
Query: 869 ---VDESLITGEAMPVAKKPGSTVIAGSINQN-------------GSLLICATHVGADTT 912
VD+S++TGE++ V K + ++NQ+ G + A G T
Sbjct: 172 TLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTE 231
Query: 913 LSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFP 972
L +I + + + P+Q+ D+ I + +A VW++ I P
Sbjct: 232 LGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVA---VWVI------NIGHFADP 282
Query: 973 GYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPL 1032
+ S R + F+ ++ + A P L T + +GT A+ +++ +
Sbjct: 283 AHGGSWLRGAV---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 1033 EMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN 1066
E V+ DKTGT+T V ++ V+ E++
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAD 373
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D +PE I G+ VV++TGDN TA +I ++GI
Sbjct: 595 GCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V P+HK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA AA++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAILGL 783
Score = 68.9 bits (167), Expect = 3e-11
Identities = 72/334 (21%), Positives = 138/334 (41%), Gaps = 39/334 (11%)
Query: 752 LATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKTSEA 808
L I +L+ ++A +E + F + ++ + +A +G W E A+ A
Sbjct: 60 LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----A 115
Query: 809 LAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM 868
+ L + ++ D + +++ + GDI++V G K P D R+IE S
Sbjct: 116 IEALKEYEPEMGKVIRSDRKGV----QRIRARDIVPGDIVEVAVGDKVPADLRLIEIKST 171
Query: 869 ---VDESLITGEAMPVAKKPGSTVIAGSINQN-------------GSLLICATHVGADTT 912
VD+S++TGE++ V K + ++NQ+ G + A G T
Sbjct: 172 TLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTE 231
Query: 913 LSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFP 972
L +I + + + P+Q+ D+ I + +A VW++ I P
Sbjct: 232 LGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVA---VWVI------NIGHFADP 282
Query: 973 GYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPL 1032
+ S R + F+ ++ + A P L T + +GT A+ +++ +
Sbjct: 283 AHGGSWLRGAV---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 1033 EMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN 1066
E V+ DKTGT+T V ++ V+ E++
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAD 373
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D +PE I G+ VV++TGDN TA +I ++GI
Sbjct: 595 GCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V P+HK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA AA++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAILGL 783
Score = 68.9 bits (167), Expect = 3e-11
Identities = 72/334 (21%), Positives = 138/334 (41%), Gaps = 39/334 (11%)
Query: 752 LATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKTSEA 808
L I +L+ ++A +E + F + ++ + +A +G W E A+ A
Sbjct: 60 LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----A 115
Query: 809 LAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM 868
+ L + ++ D + +++ + GDI++V G K P D R+IE S
Sbjct: 116 IEALKEYEPEMGKVIRSDRKGV----QRIRARDIVPGDIVEVAVGDKVPADLRLIEIKST 171
Query: 869 ---VDESLITGEAMPVAKKPGSTVIAGSINQN-------------GSLLICATHVGADTT 912
VD+S++TGE++ V K + ++NQ+ G + A G T
Sbjct: 172 TLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTE 231
Query: 913 LSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFP 972
L +I + + + P+Q+ D+ I + +A VW++ I P
Sbjct: 232 LGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVA---VWVI------NIGHFADP 282
Query: 973 GYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPL 1032
+ S R + F+ ++ + A P L T + +GT A+ +++ +
Sbjct: 283 AHGGSWLRGAV---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 1033 EMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN 1066
E V+ DKTGT+T V ++ V+ E++
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAD 373
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D +PE I G+ VV++TGDN TA +I ++GI
Sbjct: 595 GCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V P+HK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA AA++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAILGL 783
Score = 68.9 bits (167), Expect = 3e-11
Identities = 72/334 (21%), Positives = 138/334 (41%), Gaps = 39/334 (11%)
Query: 752 LATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKTSEA 808
L I +L+ ++A +E + F + ++ + +A +G W E A+ A
Sbjct: 60 LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----A 115
Query: 809 LAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM 868
+ L + ++ D + +++ + GDI++V G K P D R+IE S
Sbjct: 116 IEALKEYEPEMGKVIRSDRKGV----QRIRARDIVPGDIVEVAVGDKVPADLRLIEIKST 171
Query: 869 ---VDESLITGEAMPVAKKPGSTVIAGSINQN-------------GSLLICATHVGADTT 912
VD+S++TGE++ V K + ++NQ+ G + A G T
Sbjct: 172 TLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTE 231
Query: 913 LSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFP 972
L +I + + + P+Q+ D+ I + +A VW++ I P
Sbjct: 232 LGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVA---VWVI------NIGHFADP 282
Query: 973 GYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPL 1032
+ S R + F+ ++ + A P L T + +GT A+ +++ +
Sbjct: 283 AHGGSWLRGAV---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 1033 EMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN 1066
E V+ DKTGT+T V ++ V+ E++
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAD 373
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D +PE I G+ VV++TGDN TA +I ++GI
Sbjct: 595 GCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V P+HK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA AA++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAILGL 783
Score = 68.9 bits (167), Expect = 3e-11
Identities = 72/334 (21%), Positives = 138/334 (41%), Gaps = 39/334 (11%)
Query: 752 LATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKTSEA 808
L I +L+ ++A +E + F + ++ + +A +G W E A+ A
Sbjct: 60 LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----A 115
Query: 809 LAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM 868
+ L + ++ D + +++ + GDI++V G K P D R+IE S
Sbjct: 116 IEALKEYEPEMGKVIRSDRKGV----QRIRARDIVPGDIVEVAVGDKVPADLRLIEIKST 171
Query: 869 ---VDESLITGEAMPVAKKPGSTVIAGSINQN-------------GSLLICATHVGADTT 912
VD+S++TGE++ V K + ++NQ+ G + A G T
Sbjct: 172 TLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTE 231
Query: 913 LSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFP 972
L +I + + + P+Q+ D+ I + +A VW++ I P
Sbjct: 232 LGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVA---VWVI------NIGHFADP 282
Query: 973 GYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPL 1032
+ S R + F+ ++ + A P L T + +GT A+ +++ +
Sbjct: 283 AHGGSWLRGAV---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 1033 EMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN 1066
E V+ DKTGT+T V ++ V+ E++
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAD 373
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D +PE I G+ VV++TGDN TA +I ++GI
Sbjct: 595 GCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V P+HK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA AA++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAILGL 783
Score = 68.9 bits (167), Expect = 3e-11
Identities = 72/334 (21%), Positives = 138/334 (41%), Gaps = 39/334 (11%)
Query: 752 LATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKTSEA 808
L I +L+ ++A +E + F + ++ + +A +G W E A+ A
Sbjct: 60 LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----A 115
Query: 809 LAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM 868
+ L + ++ D + +++ + GDI++V G K P D R+IE S
Sbjct: 116 IEALKEYEPEMGKVIRSDRKGV----QRIRARDIVPGDIVEVAVGDKVPADLRLIEIKST 171
Query: 869 ---VDESLITGEAMPVAKKPGSTVIAGSINQN-------------GSLLICATHVGADTT 912
VD+S++TGE++ V K + ++NQ+ G + A G T
Sbjct: 172 TLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTE 231
Query: 913 LSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFP 972
L +I + + + P+Q+ D+ I + +A VW++ I P
Sbjct: 232 LGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVA---VWVI------NIGHFADP 282
Query: 973 GYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPL 1032
+ S R + F+ ++ + A P L T + +GT A+ +++ +
Sbjct: 283 AHGGSWLRGAV---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 1033 EMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN 1066
E V+ DKTGT+T V ++ V+ E++
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAD 373
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 87.4 bits (215), Expect = 9e-17
Identities = 59/190 (31%), Positives = 92/190 (48%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D +PE I G+ VV++TGDN TA +I ++GI
Sbjct: 595 GCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V P+HK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA AA++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAILGL 783
Score = 68.9 bits (167), Expect = 3e-11
Identities = 72/334 (21%), Positives = 138/334 (41%), Gaps = 39/334 (11%)
Query: 752 LATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKTSEA 808
L I +L+ ++A +E + F + ++ + +A +G W E A+ A
Sbjct: 60 LLVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAES----A 115
Query: 809 LAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM 868
+ L + ++ D + +++ + GDI++V G K P D R+IE S
Sbjct: 116 IEALKEYEPEMGKVIRSDRKGV----QRIRARDIVPGDIVEVAVGDKVPADLRLIEIKST 171
Query: 869 ---VDESLITGEAMPVAKKPGSTVIAGSINQN-------------GSLLICATHVGADTT 912
VD+S++TGE++ V K + ++NQ+ G + A G T
Sbjct: 172 TLRVDQSILTGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTE 231
Query: 913 LSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIVIGFLNFEIVETYFP 972
L +I + + + P+Q+ D+ I + +A VW++ I P
Sbjct: 232 LGKIRSQMAAVEPERTPLQRKLDEFGRQLSHAISVICVA---VWVI------NIGHFADP 282
Query: 973 GYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGGEPL 1032
+ S R + F+ ++ + A P L T + +GT A+ +++ +
Sbjct: 283 AHGGSWLRGAV---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSV 339
Query: 1033 EMAHKVKVVVFDKTGTITHGTPVVNQVKVLTESN 1066
E V+ DKTGT+T V ++ V+ E++
Sbjct: 340 ETLGCTSVICSDKTGTLTTNQMSVCRMFVVAEAD 373
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo
sapiens]
Length = 994
Score = 86.7 bits (213), Expect = 2e-16
Identities = 57/190 (30%), Positives = 94/190 (49%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G++ + D + E +I + + G+ V+++TGDN TA +I ++GI
Sbjct: 595 GVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
FA V PSHK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA A+++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAALGL 783
Score = 65.1 bits (157), Expect = 5e-10
Identities = 72/323 (22%), Positives = 137/323 (42%), Gaps = 50/323 (15%)
Query: 749 LIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKT 805
+++LA I+F ++A +E + F + +L + IA +G W E A+
Sbjct: 64 ILLLAACISF-------VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAEN-- 114
Query: 806 SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
A+ L + + D ++ +++ + GDI++V G K P D R++
Sbjct: 115 --AIEALKEYEPEMGKVYRADRKSV----QRIKARDIVPGDIVEVAVGDKVPADIRILAI 168
Query: 866 HSM---VDESLITGEAMPVAKKPGSTVIAGSINQNG-SLLICATHV------------GA 909
S VD+S++TGE++ V K ++NQ+ ++L T++ G
Sbjct: 169 KSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGV 228
Query: 910 DTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIV-IGFLNFEIVE 968
T + +I + + K P+QQ D+ I + +A VW++ IG N +
Sbjct: 229 GTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVA---VWLINIGHFNDPVHG 285
Query: 969 -TYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIK 1027
++F G + F+ ++ + A P L T + +GT A+ +++
Sbjct: 286 GSWFRG-----------AIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVR 334
Query: 1028 GGEPLEMAHKVKVVVFDKTGTIT 1050
+E V+ DKTGT+T
Sbjct: 335 SLPSVETLGCTSVICSDKTGTLT 357
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo
sapiens]
Length = 1001
Score = 86.7 bits (213), Expect = 2e-16
Identities = 57/190 (30%), Positives = 94/190 (49%), Gaps = 32/190 (16%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G++ + D + E +I + + G+ V+++TGDN TA +I ++GI
Sbjct: 595 GVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYT 654
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
FA V PSHK V+ LQ + AM GDG+ND+PAL A
Sbjct: 655 GREFDDLPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKA 714
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVGIPI 1372
+GIA+G+GT VA A+++VL ++ +VA+++ R ++ F+ LI + VG +
Sbjct: 715 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSNVGEVV 773
Query: 1373 AAGVFMPIGL 1382
+ +GL
Sbjct: 774 CIFLTAALGL 783
Score = 65.1 bits (157), Expect = 5e-10
Identities = 72/323 (22%), Positives = 137/323 (42%), Gaps = 50/323 (15%)
Query: 749 LIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKT 805
+++LA I+F ++A +E + F + +L + IA +G W E A+
Sbjct: 64 ILLLAACISF-------VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAEN-- 114
Query: 806 SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
A+ L + + D ++ +++ + GDI++V G K P D R++
Sbjct: 115 --AIEALKEYEPEMGKVYRADRKSV----QRIKARDIVPGDIVEVAVGDKVPADIRILAI 168
Query: 866 HSM---VDESLITGEAMPVAKKPGSTVIAGSINQNG-SLLICATHV------------GA 909
S VD+S++TGE++ V K ++NQ+ ++L T++ G
Sbjct: 169 KSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGV 228
Query: 910 DTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIV-IGFLNFEIVE 968
T + +I + + K P+QQ D+ I + +A VW++ IG N +
Sbjct: 229 GTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVA---VWLINIGHFNDPVHG 285
Query: 969 -TYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIK 1027
++F G + F+ ++ + A P L T + +GT A+ +++
Sbjct: 286 GSWFRG-----------AIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVR 334
Query: 1028 GGEPLEMAHKVKVVVFDKTGTIT 1050
+E V+ DKTGT+T
Sbjct: 335 SLPSVETLGCTSVICSDKTGTLT 357
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 84.7 bits (208), Expect = 6e-16
Identities = 54/177 (30%), Positives = 89/177 (50%), Gaps = 32/177 (18%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D + E ++ + + G+ V+++TGDN TA +I ++GI
Sbjct: 594 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 653
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V PSHK V+ LQ + AM GDG+ND+PAL A
Sbjct: 654 GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 713
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVG 1369
+GIA+G+GT VA A+++VL ++ +VA+++ R ++ F+ LI + VG
Sbjct: 714 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSNVG 769
Score = 63.2 bits (152), Expect = 2e-09
Identities = 73/322 (22%), Positives = 138/322 (42%), Gaps = 48/322 (14%)
Query: 749 LIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKT 805
+++LA I+F ++A +E + F + +L + +A +G W E A+
Sbjct: 64 ILLLAACISF-------VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAEN-- 114
Query: 806 SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
A+ L + + D ++ +++ + + GDI+++ G K P D R+
Sbjct: 115 --AIEALKEYEPEMGKVYRQDRKSV----QRIKAKDIVPGDIVEIAVGDKVPADIRLTSI 168
Query: 866 HSM---VDESLITGEAMPVAKKPGSTVIAGSINQNG-SLLICATHVGADTTLSQIV---- 917
S VD+S++TGE++ V K ++NQ+ ++L T++ A + +V
Sbjct: 169 KSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGV 228
Query: 918 -----KLVEE---AQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIV-IGFLNFEIVE 968
K+ +E + + P+QQ D+ I + IA VWI+ IG N
Sbjct: 229 NTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIA---VWIINIGHFND---- 281
Query: 969 TYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKG 1028
P + S R + F+ ++ + A P L T + +GT A+ +++
Sbjct: 282 ---PVHGGSWIRGAI---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRS 335
Query: 1029 GEPLEMAHKVKVVVFDKTGTIT 1050
+E V+ DKTGT+T
Sbjct: 336 LPSVETLGCTSVICSDKTGTLT 357
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
sapiens]
Length = 1042
Score = 84.7 bits (208), Expect = 6e-16
Identities = 54/177 (30%), Positives = 89/177 (50%), Gaps = 32/177 (18%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D + E ++ + + G+ V+++TGDN TA +I ++GI
Sbjct: 594 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 653
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V PSHK V+ LQ + AM GDG+ND+PAL A
Sbjct: 654 GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 713
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVG 1369
+GIA+G+GT VA A+++VL ++ +VA+++ R ++ F+ LI + VG
Sbjct: 714 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSNVG 769
Score = 63.2 bits (152), Expect = 2e-09
Identities = 73/322 (22%), Positives = 138/322 (42%), Gaps = 48/322 (14%)
Query: 749 LIVLATTIAFAYSLIILLVAMYERAKVNPITFFDTPPMLFVFIA---LGRWLEHIAKGKT 805
+++LA I+F ++A +E + F + +L + +A +G W E A+
Sbjct: 64 ILLLAACISF-------VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAEN-- 114
Query: 806 SEALAKLISLQATEATIVTLDSDNILLSEEQVDVELVQRGDIIKVVPGGKFPVDGRVIEG 865
A+ L + + D ++ +++ + + GDI+++ G K P D R+
Sbjct: 115 --AIEALKEYEPEMGKVYRQDRKSV----QRIKAKDIVPGDIVEIAVGDKVPADIRLTSI 168
Query: 866 HSM---VDESLITGEAMPVAKKPGSTVIAGSINQNG-SLLICATHVGADTTLSQIV---- 917
S VD+S++TGE++ V K ++NQ+ ++L T++ A + +V
Sbjct: 169 KSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGV 228
Query: 918 -----KLVEE---AQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWIV-IGFLNFEIVE 968
K+ +E + + P+QQ D+ I + IA VWI+ IG N
Sbjct: 229 NTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIA---VWIINIGHFND---- 281
Query: 969 TYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKG 1028
P + S R + F+ ++ + A P L T + +GT A+ +++
Sbjct: 282 ---PVHGGSWIRGAI---YYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRS 335
Query: 1029 GEPLEMAHKVKVVVFDKTGTIT 1050
+E V+ DKTGT+T
Sbjct: 336 LPSVETLGCTSVICSDKTGTLT 357
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
sapiens]
Length = 1015
Score = 84.7 bits (208), Expect = 6e-16
Identities = 54/177 (30%), Positives = 89/177 (50%), Gaps = 32/177 (18%)
Query: 1224 GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGI------------- 1270
G + + D + E ++ + + G+ V+++TGDN TA +I ++GI
Sbjct: 567 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFT 626
Query: 1271 ------------------TKVFAEVLPSHKVAKVKQLQEEGKRVAMVGDGINDSPALAMA 1312
+ FA V PSHK V+ LQ + AM GDG+ND+PAL A
Sbjct: 627 GREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKA 686
Query: 1313 NVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVFALIYNLVG 1369
+GIA+G+GT VA A+++VL ++ +VA+++ R ++ F+ LI + VG
Sbjct: 687 EIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMK-QFIRYLISSNVG 742
Score = 41.6 bits (96), Expect = 0.006
Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 17/214 (7%)
Query: 838 DVELVQRGDIIKVVPGGKFPVDGRVIEGHSMVDESLITGEAMPVAKKPGSTVIAGSINQN 897
D + VQR +VPG + G E S++ + + V + + + +G+
Sbjct: 133 DRKSVQRIKAKDIVPGDIVEIAG---ESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAA 189
Query: 898 GSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFVPFIVFVSIATLLVWI 957
G + G +T + +I + + + P+QQ D+ I + IA VWI
Sbjct: 190 GKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICIA---VWI 246
Query: 958 V-IGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPCSLGLATPTAVMVGT 1016
+ IG N P + S R + F+ ++ + A P L T + +GT
Sbjct: 247 INIGHFND-------PVHGGSWIRGAI---YYFKIAVALAVAAIPEGLPAVITTCLALGT 296
Query: 1017 GVGAQNGILIKGGEPLEMAHKVKVVVFDKTGTIT 1050
A+ +++ +E V+ DKTGT+T
Sbjct: 297 RRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLT 330
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 79.0 bits (193), Expect = 3e-14
Identities = 62/200 (31%), Positives = 91/200 (45%), Gaps = 44/200 (22%)
Query: 1218 VDDELC-GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT----- 1271
V D C ++ I D V+PE AI + G+ V ++TGDN TAR+IA++ GI
Sbjct: 668 VGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGED 727
Query: 1272 --------------------------------KVFAEVLPSHKVAKVKQL-----QEEGK 1294
+V A P+ K VK + E+ +
Sbjct: 728 FLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQ 787
Query: 1295 RVAMVGDGINDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVK 1353
VA+ GDG ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++ R
Sbjct: 788 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 847
Query: 1354 RIRINFVFALIYNLVGIPIA 1373
I F L N+V + +A
Sbjct: 848 SISKFLQFQLTVNVVAVIVA 867
Score = 38.5 bits (88), Expect = 0.049
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 8/105 (7%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKKPGS--TVIAG 892
QV V + GDI +V G P DG +I+ + + +DES +TGE+ V K +++G
Sbjct: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264
Query: 893 SINQNGSLLICATHVGADTTLSQIVKLV-----EEAQTSKAPIQQ 932
+ GS + T VG ++ I L+ EE + K QQ
Sbjct: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQ 309
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 79.0 bits (193), Expect = 3e-14
Identities = 62/200 (31%), Positives = 91/200 (45%), Gaps = 44/200 (22%)
Query: 1218 VDDELC-GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT----- 1271
V D C ++ I D V+PE AI + G+ V ++TGDN TAR+IA++ GI
Sbjct: 668 VGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGED 727
Query: 1272 --------------------------------KVFAEVLPSHKVAKVKQL-----QEEGK 1294
+V A P+ K VK + E+ +
Sbjct: 728 FLCLEGKEFNRRIRNEKGEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQ 787
Query: 1295 RVAMVGDGINDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVK 1353
VA+ GDG ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++ R
Sbjct: 788 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 847
Query: 1354 RIRINFVFALIYNLVGIPIA 1373
I F L N+V + +A
Sbjct: 848 SISKFLQFQLTVNVVAVIVA 867
Score = 38.5 bits (88), Expect = 0.049
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 8/105 (7%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKKPGS--TVIAG 892
QV V + GDI +V G P DG +I+ + + +DES +TGE+ V K +++G
Sbjct: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264
Query: 893 SINQNGSLLICATHVGADTTLSQIVKLV-----EEAQTSKAPIQQ 932
+ GS + T VG ++ I L+ EE + K QQ
Sbjct: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQ 309
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
Length = 1029
Score = 78.6 bits (192), Expect = 4e-14
Identities = 60/225 (26%), Positives = 105/225 (46%), Gaps = 61/225 (27%)
Query: 1220 DELC--GLIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIAS----------- 1266
D LC GLI++ D + A+ +S G++V+++TGD+ TA++IA
Sbjct: 587 DNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTET 646
Query: 1267 --------QVGITKV----------------------------------FAEVLPSHKVA 1284
++ I+KV FA P K+
Sbjct: 647 AEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLI 706
Query: 1285 KVKQLQEEGKRVAMVGDGINDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVA 1343
V+ Q G VA+ GDG+NDSPAL A++GIA+G +G+DV+ +AAD++L+ ++ +V
Sbjct: 707 IVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVT 766
Query: 1344 SIDLSRETVKRIRINFVFALIYNLVGIP-----IAAGVFMPIGLV 1383
++ R ++ + ++ L N+ I I G+ +P+G +
Sbjct: 767 GVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTI 811
Score = 45.8 bits (107), Expect = 3e-04
Identities = 53/235 (22%), Positives = 88/235 (37%), Gaps = 39/235 (16%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHS-MVDESLITGEAMPVAKKPGST------ 888
Q++V+ V GD++++ G + P D R+I VD S +TGE+ P ++ P T
Sbjct: 187 QINVQEVVLGDLVEIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLE 246
Query: 889 ------VIAGSINQNGSLLICATHVGADTTLSQIVKLVEEAQTSKAPIQQFADKLSGYFV 942
+ ++ AT G T + +I L + PI +
Sbjct: 247 TRNICFFSTNCVEGTARGIVIAT--GDSTVMGRIASLTSGLAVGQTPIAAEIEHFIHLIT 304
Query: 943 PFIVFVSIATLLVWIVIGFLNFEIVETYFPGYNRSISRTETIIRFAFQASITVLCIACPC 1002
VF+ + + +++G+ E II I ++ P
Sbjct: 305 VVAVFLGVTFFALSLLLGY-----------------GWLEAIIFL-----IGIIVANVPE 342
Query: 1003 SLGLATPTAVMVGTGVG-AQNGILIKGGEPLEMAHKVKVVVFDKTGTITHGTPVV 1056
L LAT T + T A+ L+K E +E + DKTGT+T V
Sbjct: 343 GL-LATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTV 396
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 78.2 bits (191), Expect = 6e-14
Identities = 60/192 (31%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 1225 LIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT------------- 1271
++ I D V+PE AI K G+ V ++TGDN TAR+IA++ GI
Sbjct: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
Query: 1272 ------------------------KVFAEVLPSHKVAKVKQL-----QEEGKRVAMVGDG 1302
+V A P+ K VK + E + VA+ GDG
Sbjct: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
Query: 1303 INDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVF 1361
ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++ R I F
Sbjct: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
Query: 1362 ALIYNLVGIPIA 1373
L N+V + +A
Sbjct: 847 QLTVNVVAVIVA 858
Score = 39.3 bits (90), Expect = 0.029
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKK--PGSTVIAG 892
Q+ V + GDI +V G P DG +I+G+ + +DES +TGE+ V K +++G
Sbjct: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259
Query: 893 SINQNGSLLICATHVGADTTLSQIVKLV 920
+ GS + T VG ++ I+ L+
Sbjct: 260 THVMEGSGRMVVTAVGVNSQTGIILTLL 287
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 78.2 bits (191), Expect = 6e-14
Identities = 60/192 (31%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 1225 LIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT------------- 1271
++ I D V+PE AI K G+ V ++TGDN TAR+IA++ GI
Sbjct: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
Query: 1272 ------------------------KVFAEVLPSHKVAKVKQL-----QEEGKRVAMVGDG 1302
+V A P+ K VK + E + VA+ GDG
Sbjct: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
Query: 1303 INDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVF 1361
ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++ R I F
Sbjct: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
Query: 1362 ALIYNLVGIPIA 1373
L N+V + +A
Sbjct: 847 QLTVNVVAVIVA 858
Score = 39.3 bits (90), Expect = 0.029
Identities = 28/88 (31%), Positives = 47/88 (53%), Gaps = 3/88 (3%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKK--PGSTVIAG 892
Q+ V + GDI +V G P DG +I+G+ + +DES +TGE+ V K +++G
Sbjct: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259
Query: 893 SINQNGSLLICATHVGADTTLSQIVKLV 920
+ GS + T VG ++ I+ L+
Sbjct: 260 THVMEGSGRMVVTAVGVNSQTGIILTLL 287
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
Length = 1198
Score = 77.0 bits (188), Expect = 1e-13
Identities = 59/192 (30%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 1225 LIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT------------- 1271
++ I D V+PE AI + G+ V ++TGDN TAR+IA + GI
Sbjct: 657 VVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKE 716
Query: 1272 ------------------------KVFAEVLPSHKVAKVKQL-----QEEGKRVAMVGDG 1302
+V A P+ K VK + E+ + VA+ GDG
Sbjct: 717 FNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDG 776
Query: 1303 INDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVF 1361
ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++ R I F
Sbjct: 777 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQF 836
Query: 1362 ALIYNLVGIPIA 1373
L N+V + +A
Sbjct: 837 QLTVNVVAVIVA 848
Score = 45.1 bits (105), Expect = 5e-04
Identities = 65/272 (23%), Positives = 105/272 (38%), Gaps = 48/272 (17%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKK--PGSTVIAG 892
Q+ V + GDI +V G P DG I+G+ + +DES +TGE+ V K +++G
Sbjct: 202 QIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSG 261
Query: 893 SINQNGSLLICATHVGADTTLSQIVKLV------EEAQTSKAPIQQFA------------ 934
+ GS + T VG ++ I L+ EE + KA Q A
Sbjct: 262 THVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEMQPLKSAE 321
Query: 935 -----------------DKLSGYFVPFIVFVSIATLL---VWIVIGFLNFEIVETYFPGY 974
L G V + A L+ + ++I L F V+T+
Sbjct: 322 GGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYF-TVDTFVVNK 380
Query: 975 NRSISR-----TETIIRFAFQASITVLCIACPCSLGLATPTAVMVGTGVGAQNGILIKGG 1029
+ + ++F F +TVL +A P L LA ++ ++ L++
Sbjct: 381 KPWLPECTPVYVQYFVKF-FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 439
Query: 1030 EPLEMAHKVKVVVFDKTGTITHGTPVVNQVKV 1061
+ E + DKTGT+T V Q V
Sbjct: 440 DACETMGNATAICSDKTGTLTTNRMTVVQAYV 471
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
Length = 1243
Score = 77.0 bits (188), Expect = 1e-13
Identities = 59/192 (30%), Positives = 87/192 (45%), Gaps = 43/192 (22%)
Query: 1225 LIAIADTVKPEAELAIHILKSMGLEVVLMTGDNSKTARSIASQVGIT------------- 1271
++ I D V+PE AI + G+ V ++TGDN TAR+IA + GI
Sbjct: 702 VVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKE 761
Query: 1272 ------------------------KVFAEVLPSHKVAKVKQL-----QEEGKRVAMVGDG 1302
+V A P+ K VK + E+ + VA+ GDG
Sbjct: 762 FNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDG 821
Query: 1303 INDSPALAMANVGIAIG-TGTDVAIEAADVVLIRNDLLDVVASIDLSRETVKRIRINFVF 1361
ND PAL A+VG A+G GTDVA EA+D++L ++ +V ++ R I F
Sbjct: 822 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQF 881
Query: 1362 ALIYNLVGIPIA 1373
L N+V + +A
Sbjct: 882 QLTVNVVAVIVA 893
Score = 39.3 bits (90), Expect = 0.029
Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 13/85 (15%)
Query: 836 QVDVELVQRGDIIKVVPGGKFPVDGRVIEGHSM-VDESLITGEAMPVAKK--------PG 886
Q+ V + GDI +V G P DG I+G+ + +DES +TGE+ V K G
Sbjct: 202 QIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDPMLLSG 261
Query: 887 STVIAGSINQNGSLLICATHVGADT 911
+ V+ GS G +L+ A V + T
Sbjct: 262 THVMEGS----GRMLVTAVGVNSQT 282
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.133 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,411,638
Number of Sequences: 37866
Number of extensions: 2089149
Number of successful extensions: 6043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 5671
Number of HSP's gapped (non-prelim): 251
length of query: 1500
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1385
effective length of database: 13,892,928
effective search space: 19241705280
effective search space used: 19241705280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.