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Search of human proteins with 23308749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23308749 N-acetylneuraminic acid phosphatase [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23308749 N-acetylneuraminic acid phosphatase [Homo sapiens] 503 e-143
gi|10092677 pyridoxal phosphatase [Homo sapiens] 41 8e-04
gi|108796653 phosphoglycolate phosphatase [Homo sapiens] 41 0.001
gi|13654294 haloacid dehalogenase-like hydrolase domain containi... 41 0.001
gi|33636766 phospholysine phosphohistidine inorganic pyrophospha... 34 0.10
gi|148664209 kelch-like 10 [Homo sapiens] 31 0.88
gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isof... 31 1.1
gi|211971012 acyl-Coenzyme A dehydrogenase family, member 10 iso... 31 1.1
gi|197382691 haloacid dehalogenase-like hydrolase domain contain... 31 1.1
gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens] 30 1.5
gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10 iso... 30 1.5
gi|4503917 growth arrest-specific 8 [Homo sapiens] 30 2.5
gi|239741632 PREDICTED: hypothetical protein XP_002342252 [Homo ... 29 3.3
gi|14149777 haloacid dehalogenase-like hydrolase domain containi... 29 3.3
gi|194353964 coiled-coil domain containing 157 [Homo sapiens] 29 4.3
gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens] 28 5.7
gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo ... 28 5.7
gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo ... 28 5.7
gi|4826974 RNA binding motif protein, Y-linked, family 1, member... 28 5.7
gi|56090527 RNA binding motif protein, Y-linked, family 1, membe... 28 5.7
gi|56090533 RNA binding motif protein, Y-linked, family 1, membe... 28 5.7
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 28 9.7
gi|28466969 prostaglandin D2 receptor [Homo sapiens] 28 9.7
gi|57863263 testis expressed sequence 14 isoform a [Homo sapiens] 28 9.7
gi|57863261 testis expressed sequence 14 isoform b [Homo sapiens] 28 9.7
>gi|23308749 N-acetylneuraminic acid phosphatase [Homo sapiens]
Length = 248
Score = 503 bits (1295), Expect = e-143
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC
Sbjct: 1 MGLSRVRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKEC 60
Query: 61 FHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTE 120
FHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTE
Sbjct: 61 FHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTE 120
Query: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ
Sbjct: 121 LRKEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSIFYYCCNLLGVQ 180
Query: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI
Sbjct: 181 PGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVPHYMVSSVLELPALLQSI 240
Query: 241 DCKVSMST 248
DCKVSMST
Sbjct: 241 DCKVSMST 248
>gi|10092677 pyridoxal phosphatase [Homo sapiens]
Length = 296
Score = 41.2 bits (95), Expect = 8e-04
Identities = 30/91 (32%), Positives = 42/91 (46%), Gaps = 18/91 (19%)
Query: 153 AVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKN 212
A+VVG KP+P +F + P +MVGD LETDI G G+ T +
Sbjct: 208 ALVVG------KPSPYMFECITENFSIDPARTLMVGDRLETDILFGHRCGM--TTVLTLT 259
Query: 213 GIVPLKSSP----------VPHYMVSSVLEL 233
G+ L+ + VPHY V S+ +L
Sbjct: 260 GVSRLEEAQAYLAAGQHDLVPHYYVESIADL 290
>gi|108796653 phosphoglycolate phosphatase [Homo sapiens]
Length = 321
Score = 40.8 bits (94), Expect = 0.001
Identities = 46/163 (28%), Positives = 63/163 (38%), Gaps = 31/163 (19%)
Query: 107 HMTLAEDVKAMLT---------ELRKEVR-------LLLLTNGDRQTQREKIEACACQSY 150
H L DV+A++ +L K +R LL+ TN D + E A
Sbjct: 158 HAPLEPDVRAVVVGFDPHFSYMKLTKALRYLQQPGCLLVGTNMDNRLPLENGRFIAGTGC 217
Query: 151 FDAVVVGGEQREE----KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKAT 206
V QR+ KP+ IF G+ P VMVGD L+TDI G GLK
Sbjct: 218 LVRAVEMAAQRQADIIGKPSRFIFDCVSQEYGINPERTVMVGDRLDTDILLGATCGLKTI 277
Query: 207 VWI-----------NKNGIVPLKSSPVPHYMVSSVLELPALLQ 238
+ + N+ K VP + V S+ +L LQ
Sbjct: 278 LTLTGVSTLGDVKNNQESDCVSKKKMVPDFYVDSIADLLPALQ 320
>gi|13654294 haloacid dehalogenase-like hydrolase domain containing
3 [Homo sapiens]
Length = 251
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/129 (28%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Query: 111 AEDVKAMLTELR-KEVRLLLLTNGDRQTQREKIEACACQSYFDAVVVGGEQREEKPAPSI 169
AED L E R + +RL +++N DR+ + + + +FD V+ KP P I
Sbjct: 117 AEDT---LRECRTRGLRLAVISNFDRRLEGI-LGGLGLREHFDFVLTSEAAGWPKPDPRI 172
Query: 170 FYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWINKNGIVPLKSSPVP--HYMV 227
F L ++P VGD D QG G+ + + + + P+ VP H +
Sbjct: 173 FQEALRLAHMEPVVAAHVGDNYLCDYQGPRAVGMHSFLVVGPQALDPVVRDSVPKEHILP 232
Query: 228 SSVLELPAL 236
S LPAL
Sbjct: 233 SLAHLLPAL 241
>gi|33636766 phospholysine phosphohistidine inorganic pyrophosphate
phosphatase [Homo sapiens]
Length = 270
Score = 34.3 bits (77), Expect = 0.10
Identities = 14/42 (33%), Positives = 22/42 (52%)
Query: 164 KPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKA 205
KP+P F +GV+ VM+GD + D+ G G++A
Sbjct: 189 KPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRA 230
>gi|148664209 kelch-like 10 [Homo sapiens]
Length = 608
Score = 31.2 bits (69), Expect = 0.88
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 8/75 (10%)
Query: 102 STRLQHMTLAEDVKAMLTELRKEVRL-------LLLTNGDRQTQREKIEACACQSYFDAV 154
STR + + AM E+ E+RL ++ NG + + I C+C SYF A+
Sbjct: 9 STRFHQPHMERKMSAMACEIFNELRLEGKLCDVVIKVNGFEFSAHKNI-LCSCSSYFRAL 67
Query: 155 VVGGEQREEKPAPSI 169
G EK +I
Sbjct: 68 FTSGWNNTEKKVYNI 82
>gi|48976061 acyl-Coenzyme A dehydrogenase family, member 10 isoform
b [Homo sapiens]
Length = 1059
Score = 30.8 bits (68), Expect = 1.1
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 151 FDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
FD +V + KP P I+ C LG+QP + + + D L T+++ G+ T+ +N
Sbjct: 175 FDVIVESCMEGICKPDPRIYKLCLEQLGLQPSESIFL-DDLGTNLKEAARLGIH-TIKVN 232
>gi|211971012 acyl-Coenzyme A dehydrogenase family, member 10
isoform c [Homo sapiens]
Length = 890
Score = 30.8 bits (68), Expect = 1.1
Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 151 FDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGLKATVWIN 210
FD +V + KP P I+ C LG+QP + + + D L T+++ G+ T+ +N
Sbjct: 175 FDVIVESCMEGICKPDPRIYKLCLEQLGLQPSESIFL-DDLGTNLKEAARLGIH-TIKVN 232
>gi|197382691 haloacid dehalogenase-like hydrolase domain containing
1A isoform b [Homo sapiens]
Length = 228
Score = 30.8 bits (68), Expect = 1.1
Identities = 50/222 (22%), Positives = 80/222 (36%), Gaps = 56/222 (25%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYK-----------EEAEIICDKVQV 54
V + FD+D L+DT E+ KY + E A+II D +Q+
Sbjct: 8 VTHLIFDMDGLLLDTERLYSVVFQEICNRYDKKYSWDVKSLVMGKKALEAAQIIIDVLQL 67
Query: 55 KLSKECFHPYNTCITDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDV 114
+SK EE ++E++ KL E L
Sbjct: 68 PMSK------------------EELVEESQ-----TKLKEV---------FPTAALMPGA 95
Query: 115 KAMLTELRKE-VRLLLLTNG-----DRQTQREKIEACACQSYFDAVVVGG--EQREEKPA 166
+ ++ LRK + L T+ D +T R K S F +V+G E + KP
Sbjct: 96 EKLIIHLRKHGIPFALATSSGSASFDMKTSRHK----EFFSLFSHIVLGDDPEVQHGKPD 151
Query: 167 PSIFYYCCNLLGVQPG-DCVMVGDTLETDIQGGLNAGLKATV 207
P IF C P + +V + ++ L AG++ +
Sbjct: 152 PDIFLACAKRFSPPPAMEKCLVFEDAPNGVEAALAAGMQVVM 193
>gi|41281821 SH2 domain containing 3C isoform a [Homo sapiens]
Length = 860
Score = 30.4 bits (67), Expect = 1.5
Identities = 18/51 (35%), Positives = 25/51 (49%)
Query: 72 RTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELR 122
R H E A E + G+ K ++E Y L S H L E++K T+LR
Sbjct: 166 RDVHSERAAGEPEAGSDYVKFSKEKYILDSSPEKLHKELEEELKLSSTDLR 216
>gi|211971008 acyl-Coenzyme A dehydrogenase family, member 10
isoform a [Homo sapiens]
Length = 1090
Score = 30.4 bits (67), Expect = 1.5
Identities = 16/53 (30%), Positives = 27/53 (50%), Gaps = 1/53 (1%)
Query: 151 FDAVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
FD +V + KP P I+ C LG+QP + + + D L T+++ G+
Sbjct: 175 FDVIVESCMEGICKPDPRIYKLCLEQLGLQPSESIFL-DDLGTNLKEAARLGI 226
>gi|4503917 growth arrest-specific 8 [Homo sapiens]
Length = 478
Score = 29.6 bits (65), Expect = 2.5
Identities = 31/116 (26%), Positives = 50/116 (43%), Gaps = 15/116 (12%)
Query: 10 FFDLDNTLIDTAGASRRGMLEVIKL-LQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCI 68
+F L+ I T R LE K L++K EEAE ++ QV++ Y +
Sbjct: 51 YFQLERDKIHTFWEITRRQLEEKKAELRNKDREMEEAE---ERHQVEIKV-----YKQKV 102
Query: 69 TDLRTSHWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKE 124
L H + G KLA+ K R+Q L +D++A+ EL+++
Sbjct: 103 KHLLYEHQNNLTEMKAEGTVVMKLAQ------KEHRIQESVLRKDMRALKVELKEQ 152
>gi|239741632 PREDICTED: hypothetical protein XP_002342252 [Homo
sapiens]
Length = 494
Score = 29.3 bits (64), Expect = 3.3
Identities = 22/73 (30%), Positives = 32/73 (43%), Gaps = 6/73 (8%)
Query: 16 TLIDTAGASRRGMLE---VIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYNTCITDLR 72
+L+ T GAS L ++ + H +EEAE + + Q + K CF P+ T L
Sbjct: 41 SLLPTNGASNISHLTPALAAEVCVNDNHREEEAEEVEQQQQQQKKKRCFSPWRCGRTRLN 100
Query: 73 ---TSHWEEAIQE 82
HW E E
Sbjct: 101 QGTQQHWRETKTE 113
>gi|14149777 haloacid dehalogenase-like hydrolase domain containing
2 [Homo sapiens]
Length = 259
Score = 29.3 bits (64), Expect = 3.3
Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 6/51 (11%)
Query: 153 AVVVGGEQREEKPAPSIFYYCCNLLGVQPGDCVMVGDTLETDIQGGLNAGL 203
A VVG KP + F G +P + VM+GD D+ G + G+
Sbjct: 174 ATVVG------KPEKTFFLEALRGTGCEPEEAVMIGDDCRDDVGGAQDVGM 218
>gi|194353964 coiled-coil domain containing 157 [Homo sapiens]
Length = 752
Score = 28.9 bits (63), Expect = 4.3
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 5/53 (9%)
Query: 77 EEAIQETKGGAANRKLAEE---CYFLWKSTRLQHMTLAEDVKAMLTELRKEVR 126
E+A+++ +G A R+ AEE C W+ + Q +T D+K + L +E++
Sbjct: 315 EQALKQEQG--ARRRQAEEDEQCLSEWEHDKQQLLTETSDLKTKMATLERELK 365
>gi|27597073 epoxide hydrolase 2, cytoplasmic [Homo sapiens]
Length = 555
Score = 28.5 bits (62), Expect = 5.7
Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 4/80 (5%)
Query: 114 VKAMLTELRKEVRLLLLTNG--DRQTQREKIEACACQ--SYFDAVVVGGEQREEKPAPSI 169
++A L +K +LTN D + +R+ + C+ +FD ++ + KP P I
Sbjct: 106 LQAALMLRKKGFTTAILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQI 165
Query: 170 FYYCCNLLGVQPGDCVMVGD 189
+ + + L P + V + D
Sbjct: 166 YKFLLDTLKASPSEVVFLDD 185
>gi|27262624 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 28.5 bits (62), Expect = 5.7
Identities = 10/18 (55%), Positives = 14/18 (77%)
Query: 40 HYKEEAEIICDKVQVKLS 57
HY EEAE +CD+V + +S
Sbjct: 1491 HYMEEAEAVCDRVAIMVS 1508
>gi|27262626 ATP-binding cassette, sub-family A , member 5 [Homo
sapiens]
Length = 1642
Score = 28.5 bits (62), Expect = 5.7
Identities = 10/18 (55%), Positives = 14/18 (77%)
Query: 40 HYKEEAEIICDKVQVKLS 57
HY EEAE +CD+V + +S
Sbjct: 1491 HYMEEAEAVCDRVAIMVS 1508
>gi|4826974 RNA binding motif protein, Y-linked, family 1, member A1
[Homo sapiens]
Length = 496
Score = 28.5 bits (62), Expect = 5.7
Identities = 12/22 (54%), Positives = 14/22 (63%)
Query: 143 EACACQSYFDAVVVGGEQREEK 164
EAC SY ++V GGE R EK
Sbjct: 469 EACGSSSYVASIVDGGESRSEK 490
>gi|56090527 RNA binding motif protein, Y-linked, family 1, member E
[Homo sapiens]
Length = 496
Score = 28.5 bits (62), Expect = 5.7
Identities = 12/22 (54%), Positives = 14/22 (63%)
Query: 143 EACACQSYFDAVVVGGEQREEK 164
EAC SY ++V GGE R EK
Sbjct: 469 EACGSSSYVASIVDGGESRSEK 490
>gi|56090533 RNA binding motif protein, Y-linked, family 1, member D
[Homo sapiens]
Length = 496
Score = 28.5 bits (62), Expect = 5.7
Identities = 12/22 (54%), Positives = 14/22 (63%)
Query: 143 EACACQSYFDAVVVGGEQREEK 164
EAC SY ++V GGE R EK
Sbjct: 469 EACGSSSYVASIVDGGESRSEK 490
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 27.7 bits (60), Expect = 9.7
Identities = 35/145 (24%), Positives = 61/145 (42%), Gaps = 39/145 (26%)
Query: 6 VRAVFFDLDNTLIDTAGASRRGMLEVIKLLQSKYHYKEEAEIICDKVQVKLSKECFHPYN 65
+ A+ +L++TL TA Q + K E E+ + K +E +
Sbjct: 1141 LEALKTELEDTLDSTAA-------------QQELRSKREQEV---NILKKTLEEEAKTHE 1184
Query: 66 TCITDLRTSHWE------EAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLT 119
I ++R H + E +++TK AN + A++ TL +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQ-------------TLENE----RG 1227
Query: 120 ELRKEVRLLLLTNGDRQTQREKIEA 144
EL EV++LL GD + +R+K+EA
Sbjct: 1228 ELANEVKVLLQGKGDSEHKRKKVEA 1252
>gi|28466969 prostaglandin D2 receptor [Homo sapiens]
Length = 359
Score = 27.7 bits (60), Expect = 9.7
Identities = 24/72 (33%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 168 SIFYYCCNLLGVQPGDCVMVGDTL-ETDIQGGLNA-GLKATVWINKNGIVPLKSSPVPHY 225
S FY C N V+ G+ ++G L T + G L A GL A + PL+ P Y
Sbjct: 3 SPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFY 62
Query: 226 MVSSVLELPALL 237
M+ L + LL
Sbjct: 63 MLVCGLTVTDLL 74
>gi|57863263 testis expressed sequence 14 isoform a [Homo sapiens]
Length = 1491
Score = 27.7 bits (60), Expect = 9.7
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 75 HWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNG- 133
H EE ++K ++ L++E L + T H TL ED++ L + V L L G
Sbjct: 1365 HLEEQETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEESVELQDLPKGS 1424
Query: 134 DRQT 137
+R+T
Sbjct: 1425 ERET 1428
>gi|57863261 testis expressed sequence 14 isoform b [Homo sapiens]
Length = 1451
Score = 27.7 bits (60), Expect = 9.7
Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)
Query: 75 HWEEAIQETKGGAANRKLAEECYFLWKSTRLQHMTLAEDVKAMLTELRKEVRLLLLTNG- 133
H EE ++K ++ L++E L + T H TL ED++ L + V L L G
Sbjct: 1325 HLEEQETDSKKEDSSMLLSKETEDLGEDTERAHSTLDEDLERWLQPPEESVELQDLPKGS 1384
Query: 134 DRQT 137
+R+T
Sbjct: 1385 ERET 1388
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,136,710
Number of Sequences: 37866
Number of extensions: 387342
Number of successful extensions: 874
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 852
Number of HSP's gapped (non-prelim): 32
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.