Guide to the Human Genome
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Search of human proteins with 23308597

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23308597 adenomatosis polyposis coli down-regulated 1 [Homo
sapiens]
         (514 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23308597 adenomatosis polyposis coli down-regulated 1 [Homo s...  1091   0.0  
gi|23503291 adenomatosis polyposis coli down-regulated 1-like [H...   456   e-128
gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo sap...    31   2.4  
gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo sap...    31   2.4  
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho...    30   4.0  
gi|190341084 HECT domain containing 2 isoform a [Homo sapiens]         30   5.3  

>gi|23308597 adenomatosis polyposis coli down-regulated 1 [Homo
           sapiens]
          Length = 514

 Score = 1091 bits (2822), Expect = 0.0
 Identities = 514/514 (100%), Positives = 514/514 (100%)

Query: 1   MSWPRRLLLRYLFPALLLHGLGEGSALLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLH 60
           MSWPRRLLLRYLFPALLLHGLGEGSALLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLH
Sbjct: 1   MSWPRRLLLRYLFPALLLHGLGEGSALLHPDSRSHPRSLEKSAWRAFKESQCHHMLKHLH 60

Query: 61  NGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYYGSNRCTNPTY 120
           NGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYYGSNRCTNPTY
Sbjct: 61  NGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYYGSNRCTNPTY 120

Query: 121 TLIIRGKIRLRQASWIIRGGTEADYQLHNVQVICHTEAVAEKLGQQVNRTCPGFLADGGP 180
           TLIIRGKIRLRQASWIIRGGTEADYQLHNVQVICHTEAVAEKLGQQVNRTCPGFLADGGP
Sbjct: 121 TLIIRGKIRLRQASWIIRGGTEADYQLHNVQVICHTEAVAEKLGQQVNRTCPGFLADGGP 180

Query: 181 WVQDVAYDLWREENGCECTKAVNFAMHELQLIRVEKQYLHHNLDHLVEELFLGDIHTDAT 240
           WVQDVAYDLWREENGCECTKAVNFAMHELQLIRVEKQYLHHNLDHLVEELFLGDIHTDAT
Sbjct: 181 WVQDVAYDLWREENGCECTKAVNFAMHELQLIRVEKQYLHHNLDHLVEELFLGDIHTDAT 240

Query: 241 QRMFYRPSSYQPPLQNAKNHDHACIACRIIYRSDEHHPPILPPKADLTIGLHGEWVSQRC 300
           QRMFYRPSSYQPPLQNAKNHDHACIACRIIYRSDEHHPPILPPKADLTIGLHGEWVSQRC
Sbjct: 241 QRMFYRPSSYQPPLQNAKNHDHACIACRIIYRSDEHHPPILPPKADLTIGLHGEWVSQRC 300

Query: 301 EVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFSIYARGRYSRGVLSSRVMGGT 360
           EVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFSIYARGRYSRGVLSSRVMGGT
Sbjct: 301 EVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFSIYARGRYSRGVLSSRVMGGT 360

Query: 361 EFVFKVNHMKVTPMDAATASLLNVFNGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHT 420
           EFVFKVNHMKVTPMDAATASLLNVFNGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHT
Sbjct: 361 EFVFKVNHMKVTPMDAATASLLNVFNGNECGAEGSWQVGIQQDVTHTNGCVALGIKLPHT 420

Query: 421 EYEIFKMEQDARGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASSSPRAEDLAEDS 480
           EYEIFKMEQDARGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASSSPRAEDLAEDS
Sbjct: 421 EYEIFKMEQDARGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQCASSSPRAEDLAEDS 480

Query: 481 GSSLYGRAPGRHTWSLLLAALACLVPLLHWNIRR 514
           GSSLYGRAPGRHTWSLLLAALACLVPLLHWNIRR
Sbjct: 481 GSSLYGRAPGRHTWSLLLAALACLVPLLHWNIRR 514


>gi|23503291 adenomatosis polyposis coli down-regulated 1-like [Homo
           sapiens]
          Length = 501

 Score =  456 bits (1173), Expect = e-128
 Identities = 224/465 (48%), Positives = 293/465 (63%), Gaps = 8/465 (1%)

Query: 54  HMLKHLHNGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYYGSN 113
           H  + L +    T  +PP + G W+STGCEVR GPEF+TR+Y FY +  F+A+QFYY   
Sbjct: 36  HCQQPLPDRVPSTAILPPRLNGPWISTGCEVRPGPEFLTRAYTFYPSRLFRAHQFYYEDP 95

Query: 114 RCTNPTYTLIIRGKIRLRQASWIIRGGTEADYQLHNVQVICHTEAVAEKLGQQVNRT--- 170
            C  P ++L+++GK+RLR+ASW+ RG TEADY LH V ++ H+      +  ++N+T   
Sbjct: 96  FCGEPAHSLLVKGKVRLRRASWVTRGATEADYHLHKVGIVFHSRRALVDVTGRLNQTRAG 155

Query: 171 --CPGFLADGGPWVQDVAYDLWREENGCECTKAVNFAMHELQLIRVEK--QYLHHNLDHL 226
             C   L     W+    Y+L       +C +A+   MHEL L+RV++  Q        L
Sbjct: 156 RDCARRLPPARAWLPGALYELRSARAQGDCLEALGLTMHELSLVRVQRRLQPQPRASPRL 215

Query: 227 VEELFLGDIHTDATQRMFYRPSSYQPPLQNAKNHDHACIACRIIYRSDEHHPPILPPKAD 286
           VEEL+LGDIHTD  +R  YRP+ YQ PLQ+A +H   C AC +I RSD HHPP+LPP   
Sbjct: 216 VEELYLGDIHTDPAERRHYRPTGYQRPLQSALHHVQPCPACGLIARSDVHHPPVLPPPLA 275

Query: 287 LTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNNNTWEGHYYHYSDPVCKHPTFSIYARGR 346
           L + L G WVS  CEVRP VLFLTR F FH ++ +WEG+Y+H+SDP C+ PTF++YA GR
Sbjct: 276 LPLHLGGWWVSSGCEVRPAVLFLTRLFTFHGHSRSWEGYYHHFSDPACRQPTFTVYAAGR 335

Query: 347 YSRGVLSSRVMGGTEFVFKVNHMKVTPMDAATASLLNVFNGNECGAEGSWQVGIQQDVTH 406
           Y+RG  S+RV GGTE VF+V    VTPMD  T ++LN    + CG  G+W +G ++DVT 
Sbjct: 336 YTRGTPSTRVRGGTELVFEVTRAHVTPMDQVTTAMLNFSEPSSCGGAGAWSMGTERDVTA 395

Query: 407 TNGCVALGIKLPHTEYEIFKMEQDARGRYLLFNGQRPSDGSSPDRPEKRATSYQMPLVQC 466
           TNGC+ LGI+LPH EYE+FKMEQD  G+ LLF GQRP+DGSSPD PEKR TSYQ PLV C
Sbjct: 396 TNGCLPLGIRLPHVEYELFKMEQDPLGQSLLFIGQRPTDGSSPDTPEKRPTSYQAPLVLC 455

Query: 467 ASSSPRAEDLAEDSGS-SLYGRAPGRHTWSLLLAALACLVPLLHW 510
              +P      +   S   +    G H     L  L   +  LHW
Sbjct: 456 HGEAPDFSRPPQHRPSLQKHPSTGGLHIAPFPLLPLVLGLAFLHW 500


>gi|148664242 cell recognition protein CASPR4 isoform 2 [Homo
           sapiens]
          Length = 1235

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 20/63 (31%), Positives = 30/63 (47%)

Query: 51  QCHHMLKHLHNGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYY 110
           Q + M   L   A++T ++ P   GH  S G   R+G +   R   F+ + TF AY   +
Sbjct: 863 QLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPF 922

Query: 111 GSN 113
            SN
Sbjct: 923 CSN 925


>gi|116284404 cell recognition protein CASPR4 isoform 1 [Homo
           sapiens]
          Length = 1308

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 20/63 (31%), Positives = 30/63 (47%)

Query: 51  QCHHMLKHLHNGARITVQMPPTIEGHWVSTGCEVRSGPEFITRSYRFYHNNTFKAYQFYY 110
           Q + M   L   A++T ++ P   GH  S G   R+G +   R   F+ + TF AY   +
Sbjct: 936 QLNGMTLDLEERAQVTPEVQPGCRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPF 995

Query: 111 GSN 113
            SN
Sbjct: 996 CSN 998


>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
           sapiens]
          Length = 480

 Score = 30.4 bits (67), Expect = 4.0
 Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 1/36 (2%)

Query: 59  LHNGARITVQMPPTIEGHWVSTGCEVRSGPEFITRS 94
           L +G R+ + +PPT E +W+   C VR G  F+  S
Sbjct: 108 LSHGDRLMIILPPTPEAYWICLAC-VRLGITFVPGS 142


>gi|190341084 HECT domain containing 2 isoform a [Homo sapiens]
          Length = 776

 Score = 30.0 bits (66), Expect = 5.3
 Identities = 11/42 (26%), Positives = 21/42 (50%)

Query: 278 PPILPPKADLTIGLHGEWVSQRCEVRPEVLFLTRHFIFHDNN 319
           PPI+P   ++ +G+    V   C++ PE+       + H+ N
Sbjct: 534 PPIIPSDQNIPVGICNVTVDDLCQIMPELAHGLSELLSHEGN 575


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,638,616
Number of Sequences: 37866
Number of extensions: 1060720
Number of successful extensions: 2046
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2031
Number of HSP's gapped (non-prelim): 6
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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