Guide to the Human Genome
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Search of human proteins with 226505140

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226505140 PQ loop repeat containing 1 isoform 3 [Homo
sapiens]
         (253 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226505140 PQ loop repeat containing 1 isoform 3 [Homo sapiens]     515   e-146
gi|31542733 PQ loop repeat containing 1 isoform 1 [Homo sapiens]      504   e-143
gi|226503974 PQ loop repeat containing 1 isoform 2 [Homo sapiens]     227   7e-60
gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens]         34   0.11 
gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens]         34   0.11 
gi|122937281 solute carrier family 38, member 8 [Homo sapiens]         28   5.9  
gi|196123581 cytochrome c oxidase subunit I [Homo sapiens neande...    28   7.7  
gi|251831109 cytochrome c oxidase subunit I [Homo sapiens]             28   7.7  
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...    28   7.7  
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...    28   7.7  
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...    28   7.7  

>gi|226505140 PQ loop repeat containing 1 isoform 3 [Homo sapiens]
          Length = 253

 Score =  515 bits (1327), Expect = e-146
 Identities = 253/253 (100%), Positives = 253/253 (100%)

Query: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60
           MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA
Sbjct: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60

Query: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTDFDPHHFW 120
           NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTDFDPHHFW
Sbjct: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTDFDPHHFW 120

Query: 121 QWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQS 180
           QWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQS
Sbjct: 121 QWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQS 180

Query: 181 TEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLVDLAILGQAYAFARHPQKP 240
           TEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLVDLAILGQAYAFARHPQKP
Sbjct: 181 TEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLVDLAILGQAYAFARHPQKP 240

Query: 241 APHAVHPTGTKAL 253
           APHAVHPTGTKAL
Sbjct: 241 APHAVHPTGTKAL 253


>gi|31542733 PQ loop repeat containing 1 isoform 1 [Homo sapiens]
          Length = 271

 Score =  504 bits (1298), Expect = e-143
 Identities = 253/271 (93%), Positives = 253/271 (93%), Gaps = 18/271 (6%)

Query: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60
           MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA
Sbjct: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60

Query: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFT-------- 112
           NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFT        
Sbjct: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAADSKDEE 120

Query: 113 ----------DFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL 162
                     DFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL
Sbjct: 121 VKVAPRRSFLDFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVL 180

Query: 163 TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV 222
           TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV
Sbjct: 181 TEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLV 240

Query: 223 DLAILGQAYAFARHPQKPAPHAVHPTGTKAL 253
           DLAILGQAYAFARHPQKPAPHAVHPTGTKAL
Sbjct: 241 DLAILGQAYAFARHPQKPAPHAVHPTGTKAL 271


>gi|226503974 PQ loop repeat containing 1 isoform 2 [Homo sapiens]
          Length = 132

 Score =  227 bits (579), Expect = 7e-60
 Identities = 112/112 (100%), Positives = 112/112 (100%)

Query: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60
           MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA
Sbjct: 1   MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVA 60

Query: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFT 112
           NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFT
Sbjct: 61  NILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFT 112


>gi|119943110 cystinosis, nephropathic isoform 2 [Homo sapiens]
          Length = 367

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 28/163 (17%)

Query: 84  MILTMLLMLKLCTEVRVANELNARRRSFTDFDPHHFWQWSSFSDYVQCVLAFTGVAGYIT 143
           ++LT++++++ C   R    ++     F        W ++    +V  ++A  GV  ++ 
Sbjct: 213 VVLTLIIIVQCCLYERGGQRVSWPAIGFLVLA----WLFA----FVTMIVAAVGVTTWLQ 264

Query: 144 YLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYF 203
           +L   S        ++ +    +   PQ Y N  ++STEG SI  VL+  +G +F     
Sbjct: 265 FLFCFS--------YIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQM 316

Query: 204 LLK-----------GAPLQFSVCGLLQVLVDLAILGQAYAFAR 235
            L+           G P +F + G+  ++ D+    Q +   R
Sbjct: 317 FLQSYNNDQWTLIFGDPTKFGL-GVFSIVFDVVFFIQHFCLYR 358


>gi|119943118 cystinosis, nephropathic isoform 1 [Homo sapiens]
          Length = 400

 Score = 34.3 bits (77), Expect = 0.11
 Identities = 34/163 (20%), Positives = 69/163 (42%), Gaps = 28/163 (17%)

Query: 84  MILTMLLMLKLCTEVRVANELNARRRSFTDFDPHHFWQWSSFSDYVQCVLAFTGVAGYIT 143
           ++LT++++++ C   R    ++     F        W ++    +V  ++A  GV  ++ 
Sbjct: 213 VVLTLIIIVQCCLYERGGQRVSWPAIGFLVLA----WLFA----FVTMIVAAVGVTTWLQ 264

Query: 144 YLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYF 203
           +L   S        ++ +    +   PQ Y N  ++STEG SI  VL+  +G +F     
Sbjct: 265 FLFCFS--------YIKLAVTLVKYFPQAYMNFYYKSTEGWSIGNVLLDFTGGSFSLLQM 316

Query: 204 LLK-----------GAPLQFSVCGLLQVLVDLAILGQAYAFAR 235
            L+           G P +F + G+  ++ D+    Q +   R
Sbjct: 317 FLQSYNNDQWTLIFGDPTKFGL-GVFSIVFDVVFFIQHFCLYR 358


>gi|122937281 solute carrier family 38, member 8 [Homo sapiens]
          Length = 435

 Score = 28.5 bits (62), Expect = 5.9
 Identities = 19/72 (26%), Positives = 30/72 (41%), Gaps = 8/72 (11%)

Query: 75  SPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTDFDPHHFWQWSSFSDYVQCVLA 134
           SP  W S   +   +     C E  V+   + R+RS +       W   S    + C L 
Sbjct: 211 SPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLS------HWALVSVLSLLACCLI 264

Query: 135 F--TGVAGYITY 144
           +  TGV G++T+
Sbjct: 265 YSLTGVYGFLTF 276


>gi|196123581 cytochrome c oxidase subunit I [Homo sapiens
           neanderthalensis]
          Length = 513

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 29/134 (21%), Positives = 52/134 (38%), Gaps = 15/134 (11%)

Query: 72  RFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTDFDP----------HHFWQ 121
           ++++PL   S ++   +LL+        +   L  R  + T FDP          H FW 
Sbjct: 178 QYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWF 237

Query: 122 WSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAM-LGVPQLYRNHRHQS 180
           +     Y+  +  F  ++  +TY S       E  G++ ++   M +G         H  
Sbjct: 238 FGHPEVYILILPGFGMISHIVTYYSGKK----EPFGYMGMVWAMMSIGFLGFIVWAHHMF 293

Query: 181 TEGMSIKMVLMWTS 194
           T GM +     +TS
Sbjct: 294 TVGMDVDTRAYFTS 307


>gi|251831109 cytochrome c oxidase subunit I [Homo sapiens]
          Length = 513

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 29/134 (21%), Positives = 52/134 (38%), Gaps = 15/134 (11%)

Query: 72  RFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTDFDP----------HHFWQ 121
           ++++PL   S ++   +LL+        +   L  R  + T FDP          H FW 
Sbjct: 178 QYQTPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWF 237

Query: 122 WSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAM-LGVPQLYRNHRHQS 180
           +     Y+  +  F  ++  +TY S       E  G++ ++   M +G         H  
Sbjct: 238 FGHPEVYILILPGFGMISHIVTYYSGKK----EPFGYMGMVWAMMSIGFLGFIVWAHHMF 293

Query: 181 TEGMSIKMVLMWTS 194
           T GM +     +TS
Sbjct: 294 TVGMDVDTRAYFTS 307


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 18/48 (37%), Positives = 24/48 (50%)

Query: 125 FSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQL 172
           F DY   VLAF  V G +++L    A F E L     L E  + +P+L
Sbjct: 394 FLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRL 441


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 18/48 (37%), Positives = 24/48 (50%)

Query: 125 FSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQL 172
           F DY   VLAF  V G +++L    A F E L     L E  + +P+L
Sbjct: 394 FLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRL 441


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score = 28.1 bits (61), Expect = 7.7
 Identities = 18/48 (37%), Positives = 24/48 (50%)

Query: 125 FSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQL 172
           F DY   VLAF  V G +++L    A F E L     L E  + +P+L
Sbjct: 394 FLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWEGAISIPRL 441


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.139    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,022,934
Number of Sequences: 37866
Number of extensions: 350332
Number of successful extensions: 835
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 824
Number of HSP's gapped (non-prelim): 13
length of query: 253
length of database: 18,247,518
effective HSP length: 100
effective length of query: 153
effective length of database: 14,460,918
effective search space: 2212520454
effective search space used: 2212520454
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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