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Search of human proteins with 115511028
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115511028 transmembrane 4 L six family member 19 [Homo
sapiens]
(209 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens] 424 e-119
gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens] 109 2e-24
gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens] 100 7e-22
gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens] 91 9e-19
gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens] 77 1e-14
gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens] 40 0.001
gi|11072101 rhomboid domain containing 3 [Homo sapiens] 35 0.035
gi|239753676 PREDICTED: hypothetical protein [Homo sapiens] 33 0.17
gi|239748302 PREDICTED: hypothetical protein [Homo sapiens] 33 0.17
gi|239742200 PREDICTED: hypothetical protein [Homo sapiens] 33 0.17
gi|45446752 aquaporin 8 [Homo sapiens] 29 2.5
gi|91932793 transmembrane protein 10 isoform c [Homo sapiens] 28 5.6
gi|154689796 ATPase, H+ transporting, V0 subunit isoform 2 [Homo... 28 5.6
gi|154689666 ATPase, H+ transporting, V0 subunit isoform 1 [Homo... 28 5.6
gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens] 27 9.5
>gi|115511028 transmembrane 4 L six family member 19 [Homo sapiens]
Length = 209
Score = 424 bits (1090), Expect = e-119
Identities = 209/209 (100%), Positives = 209/209 (100%)
Query: 1 MVSSPCTQASSRTCSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTG 60
MVSSPCTQASSRTCSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTG
Sbjct: 1 MVSSPCTQASSRTCSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTG 60
Query: 61 LWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALK 120
LWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALK
Sbjct: 61 LWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALK 120
Query: 121 DGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSAL 180
DGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSAL
Sbjct: 121 DGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSAL 180
Query: 181 LCISLLQLLLVVVHVINSLLGLFCSLCEK 209
LCISLLQLLLVVVHVINSLLGLFCSLCEK
Sbjct: 181 LCISLLQLLLVVVHVINSLLGLFCSLCEK 209
>gi|21265113 transmembrane 4 superfamily member 5 [Homo sapiens]
Length = 197
Score = 109 bits (272), Expect = 2e-24
Identities = 69/199 (34%), Positives = 105/199 (52%), Gaps = 16/199 (8%)
Query: 14 CSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVLTAAI 73
C+R +GLSL T L AN LL+PN + ++ L L G GGGLMVL I
Sbjct: 6 CARCVGLSLITLCLVCIVANALLLVPNGETSWTNTNHLSLQVWLMGGFIGGGLMVLCPGI 65
Query: 74 LISLMGWRYGCFSKSGLCRS---VLTALLSGGLALLGALICFVTSGVALKDGPFCMFDVS 130
G + GC +G C + +L ++ S +LGA+ C SG L++GP C+ +
Sbjct: 66 AAVRAGGK-GCCG-AGCCGNRCRMLRSVFSSAFGVLGAIYCLSVSGAGLRNGPRCLMN-- 121
Query: 131 SFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCISLLQLLL 190
++GY F+D YL +R+LW+ C P V W+V+LFS L+ S L+++L
Sbjct: 122 -------GEWGYHFEDTAGA-YLLNRTLWDR-CEAPPRVVPWNVTLFSLLVAASCLEIVL 172
Query: 191 VVVHVINSLLGLFCSLCEK 209
+ ++N+ +G+FC C K
Sbjct: 173 CGIQLVNATIGVFCGDCRK 191
>gi|21265101 transmembrane 4 superfamily member 1 [Homo sapiens]
Length = 202
Score = 100 bits (250), Expect = 7e-22
Identities = 67/202 (33%), Positives = 95/202 (47%), Gaps = 22/202 (10%)
Query: 14 CSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGL-MVLTAA 72
C+R +G SL AL AN+ L PN + Y L R +G+ GGGL M+L A
Sbjct: 6 CARCIGHSLVGLALLCIAANILLYFPNGETKYASENHLSRFVWFFSGIVGGGLLMLLPAF 65
Query: 73 ILISLMG-------WRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALKDGPFC 125
+ I L C + + SVL AL+ + G+ C + + + L +GP C
Sbjct: 66 VFIGLEQDDCCGCCGHENCGKRCAMLSSVLAALIG----IAGSGYCVIVAALGLAEGPLC 121
Query: 126 MFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCISL 185
+ + +N T A G YL D S W S C EP V W+VSLFS LL +
Sbjct: 122 LDSLGQWNYTFASTEG---------QYLLDTSTW-SECTEPKHIVEWNVSLFSILLALGG 171
Query: 186 LQLLLVVVHVINSLLGLFCSLC 207
++ +L ++ VIN +LG C C
Sbjct: 172 IEFILCLIQVINGVLGGICGFC 193
>gi|4759240 transmembrane 4 superfamily member 4 [Homo sapiens]
Length = 202
Score = 90.5 bits (223), Expect = 9e-19
Identities = 63/198 (31%), Positives = 94/198 (47%), Gaps = 15/198 (7%)
Query: 14 CSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVLTAAI 73
C+R LG +L A F AN+ L P V L G L G LM+ A +
Sbjct: 6 CARCLGGTLIPLAFFGFLANILLFFPGGKVIDDNDHLSQEIWFFGGILGSGVLMIFPALV 65
Query: 74 LISLMGWRY-GCFSKSGLCR--SVLTALLSGGLALLGALICFVTSGVALKDGPFCMFDVS 130
+ L GC G + ++ T+ + + LGA F+ S +++ GP C+ S
Sbjct: 66 FLGLKNNDCCGCCGNEGCGKRFAMFTSTIFAVVGFLGAGYSFIISAISINKGPKCLMANS 125
Query: 131 SFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCISLLQLLL 190
+ +GYPF H +YL D +LWN C EP V W+++LFS LL + +Q++L
Sbjct: 126 T--------WGYPF---HDGDYLNDEALWNK-CREPLNVVPWNLTLFSILLVVGGIQMVL 173
Query: 191 VVVHVINSLLGLFCSLCE 208
+ V+N LLG C C+
Sbjct: 174 CAIQVVNGLLGTLCGDCQ 191
>gi|20270327 transmembrane 4 L six family member 18 [Homo sapiens]
Length = 201
Score = 76.6 bits (187), Expect = 1e-14
Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 19/200 (9%)
Query: 11 SRTCSRILGLSLGTAALFAAGANVALLLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVL- 69
SR C L L AL++ N+ L PN +Y L + G+ G+M+L
Sbjct: 3 SRKCGGCLSCLLIPLALWSIIVNILLYFPNGQTSYASSNKLTNYVWYFEGICFSGIMMLI 62
Query: 70 -TAAILISLMGWRYGCFSKSGLCRSVLTALL----SGGLALLGALICFVTSGVALKDGPF 124
T +L+ Y C + +T L S G+A G C V S + L GP+
Sbjct: 63 VTTVLLVLENNNNYKCCQSENCSKKYVTLLSIIFSSLGIAFSG--YCLVISALGLVQGPY 120
Query: 125 CMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSALLCIS 184
C W+Y + + + +L D S+W CLEP+ V W++ LFS L+ +S
Sbjct: 121 C-------RTLDGWEYAF---EGTAGRFLTDSSIWIQ-CLEPAHVVEWNIILFSILITLS 169
Query: 185 LLQLLLVVVHVINSLLGLFC 204
LQ+++ ++ V+ L + C
Sbjct: 170 GLQVIICLIRVVMQLSKILC 189
>gi|188528611 transmembrane 4 L six family member 20 [Homo sapiens]
Length = 229
Score = 40.0 bits (92), Expect = 0.001
Identities = 39/177 (22%), Positives = 72/177 (40%), Gaps = 33/177 (18%)
Query: 60 GLWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVAL 119
G+ G GLM + A + R C +++G+ S L ++++ ++GAL C + S AL
Sbjct: 54 GIIGAGLMAIPATTMSLTARKRACCNNRTGMFLSSLFSVIT----VIGALYCMLISIQAL 109
Query: 120 KDGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSA----------A 169
GP S+ N + D+H ++ + +N C P+ A
Sbjct: 110 LKGPLMCNSPSNSNANCEFSL-KNISDIHPESFNL-QWFFNDSCAPPTGFNKPTSNDTMA 167
Query: 170 VVW-----------------HVSLFSALLCISLLQLLLVVVHVINSLLGLFCSLCEK 209
W H S+F LL + +L++L + ++ LG C + ++
Sbjct: 168 SGWRASSFHFDSEENKHRLIHFSVFLGLLLVGILEVLFGLSQIVIGFLGCLCGVSKR 224
>gi|11072101 rhomboid domain containing 3 [Homo sapiens]
Length = 386
Score = 35.4 bits (80), Expect = 0.035
Identities = 33/98 (33%), Positives = 45/98 (45%), Gaps = 15/98 (15%)
Query: 15 SRILGLSLGTAALFAAGANVAL----LLPNWDVTYLLRGLLGRHAMLGTGLWGGGLMVLT 70
S +L L + T L AG + L LL W V LL LG A+ G +L
Sbjct: 18 SSVLMLLMSTLWLVGAGPGLVLAPELLLDPWQVHRLLTHALGHTALPG---------LLL 68
Query: 71 AAILISLMGWRYGCF--SKSGLCRSVLTALLSGGLALL 106
+ +L+ +GW+ C + L S L AL SG LA+L
Sbjct: 69 SLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVL 106
>gi|239753676 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 33.1 bits (74), Expect = 0.17
Identities = 27/128 (21%), Positives = 54/128 (42%), Gaps = 15/128 (11%)
Query: 61 LWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALK 120
+W G L + T +L+ Y +++ L + T ++ L+++G + F + +
Sbjct: 48 IWNGALAITTGVLLLLA----YREWTQRYLGEATFTFVI---LSIMGCPLHFAIALESAL 100
Query: 121 DGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSAL 180
GP+C + S T Y F Y + + C++P +H++L +
Sbjct: 101 LGPYCFYSFSGIAGTNYLGYAVTFP--------YPYAKFPLACVDPPHYEEYHLTLQALD 152
Query: 181 LCISLLQL 188
LC+S L
Sbjct: 153 LCLSFTLL 160
>gi|239748302 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 33.1 bits (74), Expect = 0.17
Identities = 27/128 (21%), Positives = 54/128 (42%), Gaps = 15/128 (11%)
Query: 61 LWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALK 120
+W G L + T +L+ Y +++ L + T ++ L+++G + F + +
Sbjct: 48 IWNGALAITTGVLLLLA----YREWTQRYLGEATFTFVI---LSIMGCPLHFAIALESAL 100
Query: 121 DGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSAL 180
GP+C + S T Y F Y + + C++P +H++L +
Sbjct: 101 LGPYCFYSFSGIAGTNYLGYAVTFP--------YPYAKFPLACVDPPHYEEYHLTLQALD 152
Query: 181 LCISLLQL 188
LC+S L
Sbjct: 153 LCLSFTLL 160
>gi|239742200 PREDICTED: hypothetical protein [Homo sapiens]
Length = 194
Score = 33.1 bits (74), Expect = 0.17
Identities = 27/128 (21%), Positives = 54/128 (42%), Gaps = 15/128 (11%)
Query: 61 LWGGGLMVLTAAILISLMGWRYGCFSKSGLCRSVLTALLSGGLALLGALICFVTSGVALK 120
+W G L + T +L+ Y +++ L + T ++ L+++G + F + +
Sbjct: 48 IWNGALAITTGVLLLLA----YREWTQRYLGEATFTFVI---LSIMGCPLHFAIALESAL 100
Query: 121 DGPFCMFDVSSFNQTQAWKYGYPFKDLHSRNYLYDRSLWNSVCLEPSAAVVWHVSLFSAL 180
GP+C + S T Y F Y + + C++P +H++L +
Sbjct: 101 LGPYCFYSFSGIAGTNYLGYAVTFP--------YPYAKFPLACVDPPHYEEYHLTLQALD 152
Query: 181 LCISLLQL 188
LC+S L
Sbjct: 153 LCLSFTLL 160
>gi|45446752 aquaporin 8 [Homo sapiens]
Length = 261
Score = 29.3 bits (64), Expect = 2.5
Identities = 14/32 (43%), Positives = 21/32 (65%), Gaps = 1/32 (3%)
Query: 21 SLGTAALFAAGANVALLLPNWDVTYLLRGLLG 52
++ AA+ G N+ +LLP W V+ LL G+LG
Sbjct: 94 AVSLAAMLIGGLNLVMLLPYW-VSQLLGGMLG 124
>gi|91932793 transmembrane protein 10 isoform c [Homo sapiens]
Length = 131
Score = 28.1 bits (61), Expect = 5.6
Identities = 16/37 (43%), Positives = 17/37 (45%)
Query: 1 MVSSPCTQASSRTCSRILGLSLGTAALFAAGANVALL 37
M SSP T C LGL+ G L A VALL
Sbjct: 3 MTSSPVTGGKETDCGPSLGLAAGIPLLVATALLVALL 39
>gi|154689796 ATPase, H+ transporting, V0 subunit isoform 2 [Homo
sapiens]
Length = 213
Score = 28.1 bits (61), Expect = 5.6
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 23 GTAALFAAGANVAL----LLPNWDVTYLLRGLLGRHAMLG 58
G A L A+GA + L LP W +L R LLG + LG
Sbjct: 5 GPARLIASGARLLLRMLSALPGWGPAHLQRPLLGPASCLG 44
>gi|154689666 ATPase, H+ transporting, V0 subunit isoform 1 [Homo
sapiens]
Length = 130
Score = 28.1 bits (61), Expect = 5.6
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 23 GTAALFAAGANVAL----LLPNWDVTYLLRGLLGRHAMLG 58
G A L A+GA + L LP W +L R LLG + LG
Sbjct: 5 GPARLIASGARLLLRMLSALPGWGPAHLQRPLLGPASCLG 44
>gi|46488932 interferon-alpha receptor 1 precursor [Homo sapiens]
Length = 557
Score = 27.3 bits (59), Expect = 9.5
Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 9/83 (10%)
Query: 108 ALICFVTSGVALKDGPFCMFDVSSFNQTQA-WKYGYPFKD----LHSRNYLYDRSLWNSV 162
A++ ++ G KD D SF + WK ++ ++SR+ +Y S +
Sbjct: 141 AIVIHISPGT--KDSVMWALDGLSFTYSLVIWKNSSGVEERIENIYSRHKIYKLSPETTY 198
Query: 163 CLEPSAAVV--WHVSLFSALLCI 183
CL+ AA++ W + ++S + CI
Sbjct: 199 CLKVKAALLTSWKIGVYSPVHCI 221
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.328 0.140 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,619,461
Number of Sequences: 37866
Number of extensions: 308722
Number of successful extensions: 802
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 786
Number of HSP's gapped (non-prelim): 16
length of query: 209
length of database: 18,247,518
effective HSP length: 98
effective length of query: 111
effective length of database: 14,536,650
effective search space: 1613568150
effective search space used: 1613568150
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.