Guide to the Human Genome
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Search of human proteins with 224451001

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224451001 PCI domain containing 2 [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224451003 PCI domain containing 2 [Homo sapiens]                   803   0.0  
gi|224451001 PCI domain containing 2 [Homo sapiens]                   803   0.0  
gi|209976986 PCI domain containing 2 [Homo sapiens]                   803   0.0  
gi|169194708 PREDICTED: similar to eukaryotic translation initia...    36   0.070
gi|169201966 PREDICTED: similar to eukaryotic translation initia...    36   0.070
gi|169192141 PREDICTED: similar to eukaryotic translation initia...    36   0.070
gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform ...    32   1.3  
gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform ...    32   1.3  
gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform ...    32   1.3  
gi|24797153 faciogenital dysplasia protein [Homo sapiens]              31   1.7  

>gi|224451003 PCI domain containing 2 [Homo sapiens]
          Length = 399

 Score =  803 bits (2074), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE 60
           MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE
Sbjct: 1   MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE 60

Query: 61  MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN 120
           MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN
Sbjct: 61  MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN 120

Query: 121 NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF 180
           NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF
Sbjct: 121 NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF 180

Query: 181 KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC 240
           KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC
Sbjct: 181 KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC 240

Query: 241 HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK 300
           HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK
Sbjct: 241 HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK 300

Query: 301 HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV 360
           HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV
Sbjct: 301 HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV 360

Query: 361 QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC 399
           QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC
Sbjct: 361 QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC 399


>gi|224451001 PCI domain containing 2 [Homo sapiens]
          Length = 399

 Score =  803 bits (2074), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE 60
           MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE
Sbjct: 1   MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE 60

Query: 61  MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN 120
           MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN
Sbjct: 61  MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN 120

Query: 121 NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF 180
           NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF
Sbjct: 121 NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF 180

Query: 181 KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC 240
           KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC
Sbjct: 181 KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC 240

Query: 241 HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK 300
           HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK
Sbjct: 241 HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK 300

Query: 301 HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV 360
           HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV
Sbjct: 301 HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV 360

Query: 361 QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC 399
           QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC
Sbjct: 361 QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC 399


>gi|209976986 PCI domain containing 2 [Homo sapiens]
          Length = 399

 Score =  803 bits (2074), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE 60
           MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE
Sbjct: 1   MAHITINQYLQQVYEAIDSRDGASCAELVSFKHPHVANPRLQMASPEEKCQQVLEPPYDE 60

Query: 61  MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN 120
           MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN
Sbjct: 61  MFAAHLRCTYAVGNHDFIEAYKCQTVIVQSFLRAFQAHKEENWALPVMYAVALDLRVFAN 120

Query: 121 NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF 180
           NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF
Sbjct: 121 NADQQLVKKGKSKVGDMLEKAAELLMSCFRVCASDTRAGIEDSKKWGMLFLVNQLFKIYF 180

Query: 181 KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC 240
           KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC
Sbjct: 181 KINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMFDSDFKQAEEYLSFAFEHC 240

Query: 241 HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK 300
           HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK
Sbjct: 241 HRSSQKNKRMILIYLLPVKMLLGHMPTVELLKKYHLMQFAEVTRAVSEGNLLLLHEALAK 300

Query: 301 HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV 360
           HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV
Sbjct: 301 HEAFFIRCGIFLILEKLKIITYRNLFKKVYLLLKTHQLSLDAFLVALKFMQVEDVDIDEV 360

Query: 361 QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC 399
           QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC
Sbjct: 361 QCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPLSTVC 399


>gi|169194708 PREDICTED: similar to eukaryotic translation
           initiation factor 3 subunit 6 interacting protein [Homo
           sapiens]
          Length = 316

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 163 SKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMF 222
           +K  G L L  Q F+I   + K H  K L+     + L D++ +A  V +  Y+ +  + 
Sbjct: 225 AKLAGFLDLTEQEFRIQLPVFK-HKLKNLVWTSSITTLDDEFQSASEVDF--YIDKDMIH 281

Query: 223 DSDFKQAEEYLSFAFEHCHRSSQKNKRM 250
             D K A  Y +F     HR  + N+ +
Sbjct: 282 IMDTKVARRYGNFFIRQIHRFEELNRTL 309


>gi|169201966 PREDICTED: similar to eukaryotic translation
           initiation factor 3 subunit 6 interacting protein [Homo
           sapiens]
          Length = 316

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 163 SKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMF 222
           +K  G L L  Q F+I   + K H  K L+     + L D++ +A  V +  Y+ +  + 
Sbjct: 225 AKLAGFLDLTEQEFRIQLPVFK-HKLKNLVWTSSITTLDDEFQSASEVDF--YIDKDMIH 281

Query: 223 DSDFKQAEEYLSFAFEHCHRSSQKNKRM 250
             D K A  Y +F     HR  + N+ +
Sbjct: 282 IMDTKVARRYGNFFIRQIHRFEELNRTL 309


>gi|169192141 PREDICTED: similar to eukaryotic translation
           initiation factor 3 subunit 6 interacting protein [Homo
           sapiens]
          Length = 316

 Score = 35.8 bits (81), Expect = 0.070
 Identities = 24/88 (27%), Positives = 40/88 (45%), Gaps = 3/88 (3%)

Query: 163 SKKWGMLFLVNQLFKIYFKINKLHLCKPLIRAIDSSNLKDDYSTAQRVTYKYYVGRKAMF 222
           +K  G L L  Q F+I   + K H  K L+     + L D++ +A  V +  Y+ +  + 
Sbjct: 225 AKLAGFLDLTEQEFRIQLPVFK-HKLKNLVWTSSITTLDDEFQSASEVDF--YIDKDMIH 281

Query: 223 DSDFKQAEEYLSFAFEHCHRSSQKNKRM 250
             D K A  Y +F     HR  + N+ +
Sbjct: 282 IMDTKVARRYGNFFIRQIHRFEELNRTL 309


>gi|90652861 protein-tyrosine-phosphatase non-receptor 5 isoform b
           [Homo sapiens]
          Length = 533

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 14/62 (22%), Positives = 32/62 (51%)

Query: 336 HQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPL 395
           H+ +LD FL+  +F ++    +D  +  +  L+     K  + + H ++ ++  +P  PL
Sbjct: 259 HEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPL 318

Query: 396 ST 397
           S+
Sbjct: 319 SS 320


>gi|90652859 protein-tyrosine-phosphatase non-receptor 5 isoform a
           [Homo sapiens]
          Length = 565

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 14/62 (22%), Positives = 32/62 (51%)

Query: 336 HQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPL 395
           H+ +LD FL+  +F ++    +D  +  +  L+     K  + + H ++ ++  +P  PL
Sbjct: 291 HEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPL 350

Query: 396 ST 397
           S+
Sbjct: 351 SS 352


>gi|90652853 protein-tyrosine-phosphatase non-receptor 5 isoform a
           [Homo sapiens]
          Length = 565

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 14/62 (22%), Positives = 32/62 (51%)

Query: 336 HQLSLDAFLVALKFMQVEDVDIDEVQCILANLIYMGHVKGYISHQHQKLVVSKQNPFPPL 395
           H+ +LD FL+  +F ++    +D  +  +  L+     K  + + H ++ ++  +P  PL
Sbjct: 291 HEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPL 350

Query: 396 ST 397
           S+
Sbjct: 351 SS 352


>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
          Length = 961

 Score = 31.2 bits (69), Expect = 1.7
 Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 23/157 (14%)

Query: 225 DFKQAEEYLSFAFEHCHRSSQKNKRMILIYLLPVKMLLGH-----MPTVELLKKYHLMQF 279
           D +++ E ++ A EH + + +K +RM    LL V  LLG       PT EL+K+ H+++ 
Sbjct: 543 DAQKSLELIATAAEHSNAAIRKMERMHK--LLKVYELLGGEEDIVSPTKELIKEGHILKL 600

Query: 280 AEVTRAVSEGNLLLLHEAL--------AKHEAFFIRCGIFLILEKLKIITYRNLFKKVYL 331
           +       +  L+L ++ L           + F +R  I +   +LK  +  NL +   +
Sbjct: 601 SAKNGTTQDRYLILFNDRLLYCVPRLRLLGQKFSVRARIDVDGMELKESSNLNLPRTFLV 660

Query: 332 LLKTHQLSLDAFLVALKFMQVEDVDIDEVQCILANLI 368
             K   L L A        + E+   D VQ I + L+
Sbjct: 661 SGKQRSLELQA--------RTEEEKKDWVQAINSTLL 689


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.137    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,846,698
Number of Sequences: 37866
Number of extensions: 546008
Number of successful extensions: 1388
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1382
Number of HSP's gapped (non-prelim): 10
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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