Search of human proteins with 223717985

Search of human proteins with 223717985

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223717985 corticotropin releasing hormone receptor 1 isoform
4 [Homo sapiens]
         (401 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223717985 corticotropin releasing hormone receptor 1 isoform ...   826   0.0  
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2...   816   0.0  
gi|223717971 corticotropin releasing hormone receptor 1 isoform ...   801   0.0  
gi|223717978 corticotropin releasing hormone receptor 1 isoform ...   708   0.0  
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap...   572   e-163
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]    184   1e-46
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]   171   1e-42
gi|114205383 secretin receptor precursor [Homo sapiens]               171   1e-42
gi|4502547 calcitonin receptor [Homo sapiens]                         170   2e-42
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]    169   4e-42
gi|4503947 glucagon receptor [Homo sapiens]                           166   3e-41
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi...   164   2e-40
gi|5031621 calcitonin receptor-like [Homo sapiens]                    161   9e-40
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]   153   3e-37
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]          152   5e-37
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar...   148   1e-35
gi|58530851 growth hormone releasing hormone receptor isoform a ...   146   4e-35
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]     140   2e-33
gi|58530853 growth hormone releasing hormone receptor isoform b ...   125   9e-29
gi|163792198 latrophilin 3 precursor [Homo sapiens]                    88   2e-17
gi|133930786 egf-like module-containing mucin-like receptor 3 [H...    84   2e-16
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    76   5e-14
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           75   1e-13
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           75   1e-13
gi|45433552 G protein-coupled receptor 133 [Homo sapiens]              75   1e-13
gi|6912464 latrophilin 2 precursor [Homo sapiens]                      75   1e-13
gi|40807489 egf-like module containing, mucin-like, hormone rece...    71   2e-12
gi|240120161 G protein-coupled receptor 144 [Homo sapiens]             70   3e-12
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]      70   3e-12
gi|23397681 egf-like module containing, mucin-like, hormone rece...    70   3e-12

>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
           [Homo sapiens]
          Length = 401

 Score =  826 bits (2134), Expect = 0.0
 Identities = 401/401 (100%), Positives = 401/401 (100%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
           GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV
Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180

Query: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
           HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF
Sbjct: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240

Query: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300
           PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
Sbjct: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300

Query: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQVRSAI 360
           STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQVRSAI
Sbjct: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQVRSAI 360

Query: 361 RKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 401
           RKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 361 RKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 401


>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
           [Homo sapiens]
          Length = 415

 Score =  816 bits (2109), Expect = 0.0
 Identities = 401/415 (96%), Positives = 401/415 (96%), Gaps = 14/415 (3%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
           GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV
Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180

Query: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
           HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF
Sbjct: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240

Query: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300
           PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
Sbjct: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300

Query: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ----- 355
           STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ     
Sbjct: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS 360

Query: 356 ---------VRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 401
                    VRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 361 VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 415


>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
           [Homo sapiens]
          Length = 444

 Score =  801 bits (2069), Expect = 0.0
 Identities = 401/444 (90%), Positives = 401/444 (90%), Gaps = 43/444 (9%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
           GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120

Query: 121 IINYLGHCISLVALLVAFVLFLRLR-----------------------------SIRCLR 151
           IINYLGHCISLVALLVAFVLFLRLR                             SIRCLR
Sbjct: 121 IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR 180

Query: 152 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 211
           NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC
Sbjct: 181 NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC 240

Query: 212 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 271
           YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI
Sbjct: 241 YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI 300

Query: 272 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 331
           YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF
Sbjct: 301 YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF 360

Query: 332 VNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQDKHSIRARV 377
           VNPGEDEVSRVVFIYFNSFLESFQ              VRSAIRKRWHRWQDKHSIRARV
Sbjct: 361 VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV 420

Query: 378 ARAMSIPTSPTRVSFHSIKQSTAV 401
           ARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 421 ARAMSIPTSPTRVSFHSIKQSTAV 444


>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
           [Homo sapiens]
          Length = 375

 Score =  708 bits (1827), Expect = 0.0
 Identities = 360/415 (86%), Positives = 361/415 (86%), Gaps = 54/415 (13%)

Query: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA 60
           MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNIS                    
Sbjct: 1   MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNIS-------------------- 40

Query: 61  GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 120
                               +NGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
Sbjct: 41  --------------------DNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV 80

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV
Sbjct: 81  IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 140

Query: 181 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
           HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF
Sbjct: 141 HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 200

Query: 241 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 300
           PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
Sbjct: 201 PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA 260

Query: 301 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ----- 355
           STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ     
Sbjct: 261 STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS 320

Query: 356 ---------VRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 401
                    VRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
Sbjct: 321 VFYCFLNSEVRSAIRKRWHRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV 375


>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
           sapiens]
          Length = 411

 Score =  572 bits (1475), Expect = e-163
 Identities = 266/373 (71%), Positives = 317/373 (84%), Gaps = 16/373 (4%)

Query: 44  CNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQ 103
           CN ++D IGTCWPRS AG LV RPCP +F GV+YNTT N YRECL NG+WA+++NYS+C+
Sbjct: 40  CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99

Query: 104 EILNE-EKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162
            IL++ ++K  +HY +A+++NYLGHC+S+ AL+ AF+LFL LRSIRCLRN+IHWNLI+ F
Sbjct: 100 PILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTF 159

Query: 163 ILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYS 222
           ILRN  WF++QL +  EVH+SN  WCR +T  +NYF VTNFFWMF EGCYLHTAIV+TYS
Sbjct: 160 ILRNVMWFLLQL-VDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYS 218

Query: 223 TDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLI 282
           T+RLRK +F+ IGW +PFPIIVAWAIGKLYY+NE+CWFGK PG   DYIYQGP+ILVLLI
Sbjct: 219 TERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLI 278

Query: 283 NFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRV 342
           NF+FLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGED++S++
Sbjct: 279 NFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQI 338

Query: 343 VFIYFNSFLESFQ--------------VRSAIRKRWHRWQDKHSIRARVARAMSIPTSPT 388
           +FIYFNSFL+SFQ              VRSA+RKRWHRWQD HS+R  +ARAMSIPTSPT
Sbjct: 339 MFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPT 398

Query: 389 RVSFHSIKQSTAV 401
           R+SFHSIKQ+ AV
Sbjct: 399 RISFHSIKQTAAV 411


>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
          Length = 593

 Score =  184 bits (467), Expect = 1e-46
 Identities = 118/383 (30%), Positives = 174/383 (45%), Gaps = 58/383 (15%)

Query: 37  SNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWA-- 94
           S   G  C    D I  CWP    G++V  PCP + Y   +N   + YR C  NGSW   
Sbjct: 101 SRYRGRPCLPEWDHI-LCWPLGAPGEVVAVPCPDYIYD--FNHKGHAYRRCDRNGSWELV 157

Query: 95  -----ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRC 149
                   NYSEC + L  E + +  +    +I  +G+ +SL +L VA ++    R + C
Sbjct: 158 PGHNRTWANYSECVKFLTNETREREVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHC 217

Query: 150 LRNIIHWNLISAFILRNATWFV-------------------------VQLTMSPEVHQSN 184
            RN IH +L  +F+LR  + FV                          Q    P    + 
Sbjct: 218 TRNYIHMHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAG 277

Query: 185 VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIV 244
              CR+    + YF  TN++W+  EG YLH+ I + + +++   W F   GWG+P   + 
Sbjct: 278 YAGCRVAVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVA 337

Query: 245 AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR---AS 301
            W   +    N  CW          +I Q P++  +++NFI   NIVR+L TKLR   A 
Sbjct: 338 VWVSVRATLANTGCW--DLSSGNKKWIIQVPILASIVLNFILFINIVRVLATKLRETNAG 395

Query: 302 TTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVF-------IYFNSFLESF 354
                 QYRK +K+TLVL+PL G+ Y++F   P   EVS  ++       + FNSF   F
Sbjct: 396 RCDTRQQYRKLLKSTLVLMPLFGVHYIVFMATP-YTEVSGTLWQVQMHYEMLFNSFQGFF 454

Query: 355 ----------QVRSAIRKRWHRW 367
                     +V++ I+K W RW
Sbjct: 455 VAIIYCFCNGEVQAEIKKSWSRW 477


>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
          Length = 457

 Score =  171 bits (433), Expect = 1e-42
 Identities = 106/342 (30%), Positives = 176/342 (51%), Gaps = 33/342 (9%)

Query: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYREC-------LANGSWAARVNYSECQEI 105
           TCWP +P GQ+VV  CP  F         N  R C       L  G +       +    
Sbjct: 71  TCWPATPRGQVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAAS 130

Query: 106 LNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164
           L+E++     ++ +V   Y +G+ +SL  LLVA  +    R + C RN IH +L  +FIL
Sbjct: 131 LDEQQTM---FYGSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFIL 187

Query: 165 RNATWFVVQLTM-----SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVL 219
           R A  F+  L +     S +  + +VG C+     + Y  + NFFW+  EG YL+T + +
Sbjct: 188 RAAAVFIKDLALFDSGESDQCSEGSVG-CKAAMVFFQYCVMANFFWLLVEGLYLYTLLAV 246

Query: 220 TYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILV 279
           ++ ++R   W +I IGWGVP    + W I ++++++  CW      ++  +I +GP++  
Sbjct: 247 SFFSERKYFWGYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSLW--WIIKGPILTS 304

Query: 280 LLINFIFLFNIVRILMTKLRAS--TTSETIQYRKAVKATLVLLPLLGITYML--FFVNPG 335
           +L+NFI    I+RIL+ KLR      S++  Y +  ++TL+L+PL G+ Y++  FF +  
Sbjct: 305 ILVNFILFICIIRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNF 364

Query: 336 EDEVSRVVFIYFNSF-------LESF---QVRSAIRKRWHRW 367
           + EV  V  +   SF       L  F   +V++ +R++W RW
Sbjct: 365 KPEVKMVFELVVGSFQGFVVAILYCFLNGEVQAELRRKWRRW 406


>gi|114205383 secretin receptor precursor [Homo sapiens]
          Length = 440

 Score =  171 bits (433), Expect = 1e-42
 Identities = 112/343 (32%), Positives = 180/343 (52%), Gaps = 38/343 (11%)

Query: 53  TCWPRSPAGQLVVRPCPAFFYGVRYNTTNNG--YRECLANGSWAA---RVNYSECQEILN 107
           +CWP S  G++V   CP F   +R  T+ NG  +R C  +G W+    R N + C   +N
Sbjct: 74  SCWPSSVPGRMVEVECPRF---LRMLTSRNGSLFRNCTQDG-WSETFPRPNLA-CGVNVN 128

Query: 108 EEKKSKVH-YHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILR 165
           +    K H Y + + + Y +G+  SLV LLVA  +    R + C RN IH +L  +FILR
Sbjct: 129 DSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFILR 188

Query: 166 NATWFVVQLTM--SPEVHQSNV--GWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTY 221
             + F+    +  S +V   +     C+LV   + Y  + N+ W+  EG YLHT + +++
Sbjct: 189 ALSNFIKDAVLFSSDDVTYCDAHRAGCKLVMVLFQYCIMANYSWLLVEGLYLHTLLAISF 248

Query: 222 STDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCW-FGKRPGVYTDYIYQGPMILVL 280
            ++R     F+  GWG P   +  WAI + + ++  CW       ++  +I +GP+IL +
Sbjct: 249 FSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIW--WIIRGPVILSI 306

Query: 281 LINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDE 338
           LINFI   NI+RILM KLR   T  +E   Y++  ++TL+L+PL GI Y++F  +P   E
Sbjct: 307 LINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSP---E 363

Query: 339 VSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRW 367
            +  + ++F   L SFQ              V+  ++K+W +W
Sbjct: 364 DAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQQW 406


>gi|4502547 calcitonin receptor [Homo sapiens]
          Length = 474

 Score =  170 bits (431), Expect = 2e-42
 Identities = 109/371 (29%), Positives = 186/371 (50%), Gaps = 40/371 (10%)

Query: 41  GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV--- 97
           G  CN + D    CW  +PAG L  + CP +F    ++ +    + C   G W       
Sbjct: 69  GPYCNRTWDG-WLCWDDTPAGVLSYQFCPDYFPD--FDPSEKVTKYCDEKGVWFKHPENN 125

Query: 98  ----NYSECQEILNEE-KKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRN 152
               NY+ C     E+ K + V Y++A++    GH +S+  L+++  +F+  RS+ C R 
Sbjct: 126 RTWSNYTMCNAFTPEKLKNAYVLYYLAIV----GHSLSIFTLVISLGIFVFFRSLGCQRV 181

Query: 153 IIHWNLISAFILRNATWFV--VQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210
            +H N+   +IL +    +  V++  + E+ + +   C+++   + Y    N+FWM  EG
Sbjct: 182 TLHKNMFLTYILNSMIIIIHLVEVVPNGELVRRDPVSCKILHFFHQYMMACNYFWMLCEG 241

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YLHT IV+   T++ R   +  +GWG P       AI +  Y N+ CW      +   Y
Sbjct: 242 IYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLL--Y 299

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330
           I  GP++  L++NF FL NIVR+L+TK+R +  +E+  Y KAVKAT++L+PLLGI +++F
Sbjct: 300 IIHGPVMAALVVNFFFLLNIVRVLVTKMRETHEAESHMYLKAVKATMILVPLLGIQFVVF 359

Query: 331 FVNPGEDEVSRVV------FIYFNSFLESF-------QVRSAIRKRW--------HRWQD 369
              P    + ++        I+F  F  +        +V++ ++++W         RW  
Sbjct: 360 PWRPSNKMLGKIYDYVMHSLIHFQGFFVATIYCFCNNEVQTTVKRQWAQFKIQWNQRWGR 419

Query: 370 KHSIRARVARA 380
           + S R+  A A
Sbjct: 420 RPSNRSARAAA 430


>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
          Length = 550

 Score =  169 bits (428), Expect = 4e-42
 Identities = 106/364 (29%), Positives = 166/364 (45%), Gaps = 54/364 (14%)

Query: 54  CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSW-------AARVNYSECQEIL 106
           CWPR   G++   PCP + Y   +N     +R C  NG+W           NYS+C   L
Sbjct: 72  CWPRGTVGKISAVPCPPYIYD--FNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFL 129

Query: 107 NEEKK-SKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFIL 164
             +    K  +   + + Y +G+ IS  +L VA ++    R + C RN IH +L  +F+L
Sbjct: 130 QPDISIGKQEFFERLYVMYTVGYSISFGSLAVAILIIGYFRRLHCTRNYIHMHLFVSFML 189

Query: 165 RNATWFVVQLTM-----------------------SPEVHQSNVGWCRLVTAAYNYFHVT 201
           R  + FV    +                       +  V +S    C++    + YF  T
Sbjct: 190 RATSIFVKDRVVHAHIGVKELESLIMQDDPQNSIEATSVDKSQYIGCKIAVVMFIYFLAT 249

Query: 202 NFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFG 261
           N++W+  EG YLH  I + + +D    W FI IGWG P   + AWA+ +    + +CW  
Sbjct: 250 NYYWILVEGLYLHNLIFVAFFSDTKYLWGFILIGWGFPAAFVAAWAVARATLADARCWEL 309

Query: 262 KRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKL---RASTTSETIQYRKAVKATLV 318
               +   +IYQ P++  + +NFI   N VR+L TK+    A       QYRK  K+TLV
Sbjct: 310 SAGDI--KWIYQAPILAAIGLNFILFLNTVRVLATKIWETNAVGHDTRKQYRKLAKSTLV 367

Query: 319 LLPLLGITYMLFFVNPGED-----EVSRVVFIYFNSFLESF----------QVRSAIRKR 363
           L+ + G+ Y++F   P        E+     ++FNSF   F          +V++ ++K 
Sbjct: 368 LVLVFGVHYIVFVCLPHSFTGLGWEIRMHCELFFNSFQGFFVSIIYCYCNGEVQAEVKKM 427

Query: 364 WHRW 367
           W RW
Sbjct: 428 WSRW 431


>gi|4503947 glucagon receptor [Homo sapiens]
          Length = 477

 Score =  166 bits (420), Expect = 3e-41
 Identities = 123/417 (29%), Positives = 191/417 (45%), Gaps = 56/417 (13%)

Query: 5   PQLRLVKALLLLGLNPVSASLQ-------------DQHCESLSLASNISGLQCNASVDLI 51
           PQ  L+  LLLL   P   S Q             DQ   +LSL    + L CN + D  
Sbjct: 6   PQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKY 65

Query: 52  GTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARV------NYSECQ-- 103
            +CWP +PA       CP +            ++ C  +G W          + S+CQ  
Sbjct: 66  -SCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMD 124

Query: 104 -EILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162
            E +  +K+    Y    ++  +G+ +SL ALL+A  +   L  + C RN IH NL ++F
Sbjct: 125 GEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASF 184

Query: 163 ILRNATWFVVQ--------------LTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFG 208
           +L+ ++  V+               L++S  +    V  CR+      Y  V N+ W+  
Sbjct: 185 VLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLV 244

Query: 209 EGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGK-RPGVY 267
           EG YLH  + L    +R    +++ IGWG P   +V WA+ K  ++N +CW      G +
Sbjct: 245 EGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFW 304

Query: 268 TDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITY 327
             +I + P+ L +LINF     IV++L+ KLRA     T    +  K+TL L+PLLG+  
Sbjct: 305 --WILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHE 362

Query: 328 MLF-FVNPGEDE-VSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQ 368
           ++F FV     +   R   ++F+ FL SFQ              V+S +R+RWHRW+
Sbjct: 363 VVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWR 419


>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
           sapiens]
          Length = 553

 Score =  164 bits (414), Expect = 2e-40
 Identities = 121/415 (29%), Positives = 191/415 (46%), Gaps = 59/415 (14%)

Query: 3   GHPQLRLVKALLLLGLNPVSASLQDQHCESLS---------LASNISGLQCNASVDLIGT 53
           G P L LV   LL+ +  V+ SL ++     +         L    SG+ CN + D    
Sbjct: 49  GRPFLTLV---LLVSIKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQY-V 104

Query: 54  CWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNY-------SECQEIL 106
           CWP S  G + V PCP++       ++   YR CLA G+W    N        SEC E  
Sbjct: 105 CWPHSSPGNVSV-PCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSE-- 161

Query: 107 NEEKKSKVHYHVAV----IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAF 162
           N   K  V  +  +    ++  +G+  SL++L +A  L L LR + C RN IH NL ++F
Sbjct: 162 NHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASF 221

Query: 163 ILRNATWFVVQLTMSPEVHQ---SNVGW----------CRLVTAAYNYFHVTNFFWMFGE 209
           ILR     V  +       +   +  GW          CR V    +YF   N+ W+  E
Sbjct: 222 ILRTLAVLVKDVVFYNSYSKRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVE 281

Query: 210 GCYLHTAIVLTYSTDRLRKW-MFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYT 268
           G YLHT +  T   +R R W  ++ +GW  P   +V W   + + +N  CW         
Sbjct: 282 GLYLHTLLEPTVLPER-RLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCW-TTNGNKKI 339

Query: 269 DYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYM 328
            +I +GPM+L + +NF     I+++L++KL+A          +  K+TLVL+PLLG+  +
Sbjct: 340 WWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEI 399

Query: 329 LF-FVNPGEDE-VSRVVFIYFNSFLESF--------------QVRSAIRKRWHRW 367
           LF F+   + E  ++++ ++    L SF              +V++ +RK W R+
Sbjct: 400 LFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRKYWVRF 454


>gi|5031621 calcitonin receptor-like [Homo sapiens]
          Length = 461

 Score =  161 bits (408), Expect = 9e-40
 Identities = 104/352 (29%), Positives = 176/352 (50%), Gaps = 34/352 (9%)

Query: 41  GLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAAR---- 96
           G+ CN + D    CW    AG   ++ CP +F    ++ +    + C  +G+W       
Sbjct: 62  GVYCNRTWDG-WLCWNDVAAGTESMQLCPDYFQD--FDPSEKVTKICDQDGNWFRHPASN 118

Query: 97  ---VNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNI 153
               NY++C    +E+ K+ ++     II   GH +S+ +LL++  +F   +S+ C R  
Sbjct: 119 RTWTNYTQCNVNTHEKVKTALNLFYLTII---GHGLSIASLLISLGIFFYFKSLSCQRIT 175

Query: 154 IHWNLISAFILRNATWFVVQLTM---SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEG 210
           +H NL  +F+  N+   ++ LT    +  +  +N   C++    + Y    N+FWM  EG
Sbjct: 176 LHKNLFFSFVC-NSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEG 234

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YLHT IV+    ++     +  +GWG P       AI +  Y N+ CW       +  Y
Sbjct: 235 IYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISS--DTHLLY 292

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLF 330
           I  GP+   LL+N  FL NIVR+L+TKL+ +  +E+  Y KAV+ATL+L+PLLGI ++L 
Sbjct: 293 IIHGPICAALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLI 352

Query: 331 FVNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQ 368
              P E +++  V+ Y    L  FQ              V++ +R+ W++++
Sbjct: 353 PWRP-EGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYK 403


>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
          Length = 438

 Score =  153 bits (386), Expect = 3e-37
 Identities = 103/341 (30%), Positives = 167/341 (48%), Gaps = 18/341 (5%)

Query: 26  QDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYR 85
           ++  C  L  +       C+   D I TCW  +  G+ V  PCP  F    Y+   N  +
Sbjct: 34  EETKCAELLRSQTEKHKACSGVWDNI-TCWRPANVGETVTVPCPKVFSNF-YSKAGNISK 91

Query: 86  ECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRL 144
            C ++G      ++ +     + E +SK+ +++ V   Y LG+ +SL++L    ++    
Sbjct: 92  NCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLF 151

Query: 145 RSIRCLRNIIHWNLISAFILRNATWFVVQLTM--------SPEVHQSNVGWCRLVTAAYN 196
           R + C RN IH NL  +FILR  +  V    +         P+   S VG C+L      
Sbjct: 152 RKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVG-CKLSLVFLQ 210

Query: 197 YFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNE 256
           Y  + NFFW+  EG YLHT +V      R     ++ IGWG+P   I AW   +LY ++ 
Sbjct: 211 YCIMANFFWLLVEGLYLHTLLVAMLPPRRC-FLAYLLIGWGLPTVCIGAWTAARLYLEDT 269

Query: 257 KCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVK 314
            CW      V   ++ + P+++ +++NF+   +I+RIL+ KL +     ++  QY++  K
Sbjct: 270 GCWDTNDHSV-PWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAK 328

Query: 315 ATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ 355
           +TL+L+PL G+ YM+F V P    +S    I F   L SFQ
Sbjct: 329 STLLLIPLFGVHYMVFAVFP--ISISSKYQILFELCLGSFQ 367


>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
          Length = 463

 Score =  152 bits (384), Expect = 5e-37
 Identities = 109/374 (29%), Positives = 172/374 (45%), Gaps = 53/374 (14%)

Query: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVN--- 98
           L CN + D    CWP    G  V   CP +          + YR C A G W  + N   
Sbjct: 60  LFCNRTFDEYA-CWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSL 118

Query: 99  ----YSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRCLRNI 153
                SEC+E    E+ S     + + I Y +G+ +S  AL++A  + L  R + C RN 
Sbjct: 119 PWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNY 178

Query: 154 IHWNLISAFILRNATWFVVQLTM------SPEVHQSNVGW-----------CRLVTAAYN 196
           IH NL ++FILR  + F+    +      + + HQ    W           CRLV     
Sbjct: 179 IHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQ----WDGLLSYQDSLSCRLVFLLMQ 234

Query: 197 YFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNE 256
           Y    N++W+  EG YL+T +  +  +++    +++ IGWGVP   +V W I K  Y++E
Sbjct: 235 YCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDE 294

Query: 257 KCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKAT 316
            CW  +   +    I + P++  + +NF+    ++ I+++KL+A+   +T    +  K+T
Sbjct: 295 GCW-TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKST 353

Query: 317 LVLLPLLGITYMLF-FVNPGEDEVSRVVFIYFNSFLE----SFQ--------------VR 357
           L L+PLLG   ++F FV    DE +R    +   F E    SFQ              V+
Sbjct: 354 LTLIPLLGTHEVIFAFV---MDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQ 410

Query: 358 SAIRKRWHRWQDKH 371
              RK W RW+ +H
Sbjct: 411 LEFRKSWERWRLEH 424


>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
           receptor type I precursor [Homo sapiens]
          Length = 468

 Score =  148 bits (373), Expect = 1e-35
 Identities = 115/419 (27%), Positives = 190/419 (45%), Gaps = 72/419 (17%)

Query: 12  ALLLLGLNPVSAS------LQDQHCESLSLASNISGLQ-----CNASVDLIGTCWPRSPA 60
           ALLLL + P   S       Q    E +  A+ + G       C    D I TCW  +  
Sbjct: 11  ALLLLPMAPAMHSDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNI-TCWKPAHV 69

Query: 61  GQLVVRPCPAFF------------------YG------------VRYNTTNNGYRECLAN 90
           G++V+  CP  F                  +G            V  N T +G+ E   +
Sbjct: 70  GEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPH 129

Query: 91  GSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRLRSIRC 149
              A   +  E       E   + +Y+++V   Y +G+  SLV L  A V+  R R + C
Sbjct: 130 YFDACGFDEYE------SETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHC 183

Query: 150 LRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSN----VGWCRLVTAAYNYFHVTNFFW 205
            RN IH NL  +F+LR  + F+    +  E   ++       C+ V   ++Y  V+N+FW
Sbjct: 184 TRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFW 243

Query: 206 MFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPG 265
           +F EG YL T +V T+  +R   + +  IGWG P   +  WA  +LY+D+  CW      
Sbjct: 244 LFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCW-DMNDS 302

Query: 266 VYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLL 323
               ++ +GP++  +++NF+    I+ IL+ KL++     +E+  Y +  ++TL+L+PL 
Sbjct: 303 TALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIPLF 362

Query: 324 GITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWHRWQ 368
           GI Y +F  +P  + VS+   + F   L SFQ              V++ I+++W  W+
Sbjct: 363 GIHYTVFAFSP--ENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWK 419


>gi|58530851 growth hormone releasing hormone receptor isoform a
           precursor [Homo sapiens]
          Length = 423

 Score =  146 bits (368), Expect = 4e-35
 Identities = 106/351 (30%), Positives = 163/351 (46%), Gaps = 38/351 (10%)

Query: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111

Query: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164

Query: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS--ETIQYRKAVKATLVLLPLLGITYM 328
           I +GP++L + +NF    NI+RIL+ KL  +  S     QY +  K+TL L+PL GI Y+
Sbjct: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYI 343

Query: 329 LFFVNPGEDEVSRVVFIYFNSFLESFQ--------------VRSAIRKRWH 365
           +F   P  D     + +     L SFQ              VR+ I ++WH
Sbjct: 344 IFNFLP--DNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISRKWH 392


>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
          Length = 466

 Score =  140 bits (354), Expect = 2e-33
 Identities = 102/376 (27%), Positives = 172/376 (45%), Gaps = 40/376 (10%)

Query: 31  ESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYRECLAN 90
           E+L+ A   SGL CN S D+   CW  +         CP +     +       R+C ++
Sbjct: 48  ETLAAAEPPSGLACNGSFDMY-VCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCGSD 106

Query: 91  GSWAARVNYSECQEILNEEKKS-----KVHYHVAVIINYLGHCISLVALLVAFVLFLRLR 145
           G W    ++++C+   N EK       ++      ++  +G+ +SL  LL+A ++    R
Sbjct: 107 GQWGLWRDHTQCE---NPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSLFR 163

Query: 146 SIRCLRNIIHWNLISAFILRNATWFVV-QLTMSPEVH---QSNVGW------CRLVTAAY 195
            + C RN IH NL ++F+LR A      +L   P  +   Q+   W      CR      
Sbjct: 164 RLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQALAACRTAQIVT 223

Query: 196 NYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDN 255
            Y    N+ W+  EG YLH+ +VL   ++      ++ +GWG P   ++ W I +  Y+N
Sbjct: 224 QYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRYLYEN 283

Query: 256 EKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKA 315
            +CW          +I + P+++ +LINF+    I+ IL++KLR           +  ++
Sbjct: 284 TQCWERNEVKAIW-WIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYRLRLARS 342

Query: 316 TLVLLPLLGITYMLFFVNPGEDEVSRVVFIY----FNSFLESFQ--------------VR 357
           TL L+PLLG+  ++F   P  +E +R    +    F  FL SFQ              V+
Sbjct: 343 TLTLVPLLGVHEVVF--APVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFINKEVQ 400

Query: 358 SAIRKRWHRWQDKHSI 373
           S IR+ WH  + + S+
Sbjct: 401 SEIRRGWHHCRLRRSL 416


>gi|58530853 growth hormone releasing hormone receptor isoform b
           precursor [Homo sapiens]
          Length = 337

 Score =  125 bits (313), Expect = 9e-29
 Identities = 83/274 (30%), Positives = 130/274 (47%), Gaps = 20/274 (7%)

Query: 42  LQCNASVDLIGTCWPRSPAGQLVVRPCPAFFY-------GVRYNTTNNGYRECLANGSWA 94
           L C A+ D +  CWP + +G+ V  PCP FF         V+ + T  G+ E       A
Sbjct: 53  LGCPATWDGL-LCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVA 111

Query: 95  ARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNII 154
             V      E+L EE+    ++    II  +GH IS+VAL VA  + + LR + C RN +
Sbjct: 112 CPVPL----ELLAEEES---YFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYV 164

Query: 155 HWNLISAFILRNATWFVVQLTMSPEVHQSNVGW----CRLVTAAYNYFHVTNFFWMFGEG 210
           H  L + FIL+    F+    +       +  +    C++  AA ++  +TNF W+  E 
Sbjct: 165 HTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEA 224

Query: 211 CYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDY 270
            YL+  +  T  + R   W  +  GWG+P      W   KL +++  CW       Y  +
Sbjct: 225 VYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYW-W 283

Query: 271 IYQGPMILVLLINFIFLFNIVRILMTKLRASTTS 304
           I +GP++L + +NF    NI+RIL+ KL  +  S
Sbjct: 284 IIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGS 317


>gi|163792198 latrophilin 3 precursor [Homo sapiens]
          Length = 1469

 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 82/300 (27%), Positives = 131/300 (43%), Gaps = 36/300 (12%)

Query: 74   GVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVA 133
            G R  TTN  +  C  N       N++     +  +    VH  +  +I ++G  +SLV 
Sbjct: 836  GCRLLTTNKTHTTCSCNHL----TNFAVLMAHVEVKHSDAVHDLLLDVITWVGILLSLVC 891

Query: 134  LLVAFVLFLRLRSIRCLRNIIHWNL-ISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVT 192
            LL+    F   R ++  RN IH NL IS F+        +  T  P         C +  
Sbjct: 892  LLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLIGINRTDQPIA-------CAVFA 944

Query: 193  AAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPII-VAWAIGKL 251
            A  ++F +  F WMF EG  L+  +V  + ++  R+  F  +G+G+P  I+ V+ A+   
Sbjct: 945  ALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRKYFYLVGYGMPALIVAVSAAVDYR 1004

Query: 252  YYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFL-------FNIVRILMTKLRASTT 303
             Y  +K CW   R   Y  + + GP  L++++N IFL       F+   IL  +   S  
Sbjct: 1005 SYGTDKVCWL--RLDTYFIWSFIGPATLIIMLNVIFLGIALYKMFHHTAILKPE---SGC 1059

Query: 304  SETIQY-------RKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESF 354
             + I Y       +  V   + LL LLG+T+   L ++N     +   +F  FNS    F
Sbjct: 1060 LDNINYEDNRPFIKSWVIGAIALLCLLGLTWAFGLMYINE-STVIMAYLFTIFNSLQGMF 1118


>gi|133930786 egf-like module-containing mucin-like receptor 3 [Homo
           sapiens]
          Length = 652

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 76/268 (28%), Positives = 122/268 (45%), Gaps = 28/268 (10%)

Query: 118 VAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMS 177
           V  +I Y+G  +SL+ LL+A + FL  ++IR     +H  L     L +  + V      
Sbjct: 355 VLTVITYVGLSVSLLCLLLAALTFLLCKAIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTE 414

Query: 178 PEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYL----HTAIVLTYST-DRLRKWMFI 232
           P+V       C ++  A +Y ++  F WM  EG +L        V+ YS+ +RL KW+  
Sbjct: 415 PKV------LCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMF 468

Query: 233 CIGWGVPFPIIVAWAIG--KLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNI 290
            +G+GVP   +   A     LY   ++CW     G    ++  GP+  +   N +    +
Sbjct: 469 PVGYGVPAVTVAISAASWPHLYGTADRCWLHLDQGFMWSFL--GPVCAIFSANLVLFILV 526

Query: 291 VRILMTKLRASTTSE--TIQYRK--AVKATLVLLPLLGITYMLFFVNPG-EDEVSRVVFI 345
             IL  KL +S  SE  TIQ  +  A KAT  L  +LG T+ L  +  G   +V   +F 
Sbjct: 527 FWILKRKL-SSLNSEVSTIQNTRMLAFKATAQLF-ILGCTWCLGLLQVGPAAQVMAYLFT 584

Query: 346 YFNS------FLESFQVRSAIRKRWHRW 367
             NS      FL    +   ++K++ +W
Sbjct: 585 IINSLQGFFIFLVYCLLSQQVQKQYQKW 612


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 64/241 (26%), Positives = 119/241 (49%), Gaps = 22/241 (9%)

Query: 125  LGHCISLVALLVAFVLFLRL-RSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQS 183
            +G  +S + LL+  ++++ + R IR  R++I  N   + I  NA      L +  +    
Sbjct: 953  VGCGVSSLTLLMLVIIYVSVWRYIRSERSVILINFCLSIISSNA------LILIGQTQTR 1006

Query: 184  NVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPII 243
            N   C LV A  ++F +++F W+  E    + A+   +  +RL +  F+C+GWG+P  ++
Sbjct: 1007 NKVVCTLVAAFLHFFFLSSFCWVLTEAWQSYMAVT-GHLRNRLIRKRFLCLGWGLP-ALV 1064

Query: 244  VAWAIG----KLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLR 299
            VA ++G    K Y     CW     G+   Y + GP   V+L+N +    +   L++K  
Sbjct: 1065 VAISVGFTKAKGYSTMNYCWLSLEGGLL--YAFVGPAAAVVLVNMVIGILVFNKLVSK-- 1120

Query: 300  ASTTSETIQYRKAVK--ATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFLESFQ 355
               T + ++ R      ++ V+LPLL +T+M  +  V      + +++F  F+S LE F 
Sbjct: 1121 DGITDKKLKERAGASLWSSCVVLPLLALTWMSAVLAVTDRRSALFQILFAVFDS-LEGFV 1179

Query: 356  V 356
            +
Sbjct: 1180 I 1180


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 69/258 (26%), Positives = 115/258 (44%), Gaps = 17/258 (6%)

Query: 121  IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
            +I ++G  ISLV L +    F  LR ++  RN IH NL     L    + V       E+
Sbjct: 862  VITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEI 921

Query: 181  HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
                   C +     +YF +  F W+  EG +L+  +V  + ++  R   +   G+  P 
Sbjct: 922  A------CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPA 975

Query: 241  PII-VAWAIGKLYYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR--ILMT 296
             ++ +A AI    Y  EK CW   R   Y  + + GP+  V+++N +FL   +   I  +
Sbjct: 976  LVVGIAAAIDYRSYGTEKACWL--RVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSS 1033

Query: 297  KLRASTTSETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSF--LE 352
             +    +S     +      + LL LLG+T+   L F+N  E  V   +F  FN+F  + 
Sbjct: 1034 SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINK-ESVVMAYLFTTFNAFQGVF 1092

Query: 353  SFQVRSAIRKRWHRWQDK 370
             F    A++K+ H+   K
Sbjct: 1093 IFVFHCALQKKVHKEYSK 1110


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 69/258 (26%), Positives = 115/258 (44%), Gaps = 17/258 (6%)

Query: 121  IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
            +I ++G  ISLV L +    F  LR ++  RN IH NL     L    + V       E+
Sbjct: 857  VITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEI 916

Query: 181  HQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPF 240
                   C +     +YF +  F W+  EG +L+  +V  + ++  R   +   G+  P 
Sbjct: 917  A------CPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPA 970

Query: 241  PII-VAWAIGKLYYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR--ILMT 296
             ++ +A AI    Y  EK CW   R   Y  + + GP+  V+++N +FL   +   I  +
Sbjct: 971  LVVGIAAAIDYRSYGTEKACWL--RVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSS 1028

Query: 297  KLRASTTSETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSF--LE 352
             +    +S     +      + LL LLG+T+   L F+N  E  V   +F  FN+F  + 
Sbjct: 1029 SVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINK-ESVVMAYLFTTFNAFQGVF 1087

Query: 353  SFQVRSAIRKRWHRWQDK 370
             F    A++K+ H+   K
Sbjct: 1088 IFVFHCALQKKVHKEYSK 1105


>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
          Length = 874

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 58/244 (23%), Positives = 113/244 (46%), Gaps = 24/244 (9%)

Query: 122 INYLGHCISLVALLVAFVLFLRLRSIRCLRNI---IHWNLISAFILRNATWFVVQLTMSP 178
           I+Y+G  +S++ L+   V F  L S+  +RN    IH NL  A ++      ++   + P
Sbjct: 569 ISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVL-LLISFRLEP 627

Query: 179 EVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGV 238
                    C+++    +YF ++ F WM  EG +L++ ++  + ++  +   +  +GWG 
Sbjct: 628 GTTP-----CQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDSKHRYYYGMGWGF 682

Query: 239 PFPIIV---AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRIL- 294
           P  I +   ++A+   Y  +  CW     G    + +  P + V+++N   L  + R++ 
Sbjct: 683 PLLICIISLSFAMDS-YGTSNNCWLSLASGAI--WAFVAPALFVIVVNIGILIAVTRVIS 739

Query: 295 -MTKLRASTTSETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVSRVVFIYFNSFL 351
            ++        +   ++   KA  VLLP+LG +++  +  VN        VVF Y  + L
Sbjct: 740 QISADNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNG-----CAVVFQYMFATL 794

Query: 352 ESFQ 355
            S Q
Sbjct: 795 NSLQ 798


>gi|6912464 latrophilin 2 precursor [Homo sapiens]
          Length = 1403

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 72/250 (28%), Positives = 112/250 (44%), Gaps = 23/250 (9%)

Query: 111  KSKVHYHVAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNL-ISAFILRNATW 169
            K  VH  +  +I ++G  ISLV L +    F   R ++  RN IH NL I+ FI      
Sbjct: 826  KDGVHELLLTVITWVGIVISLVCLAICIFTFCFFRGLQSDRNTIHKNLCINLFIAE---- 881

Query: 170  FVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKW 229
            F+  + +    +      C +     ++F +  F WM  EG  L+  +V  + ++  RK 
Sbjct: 882  FIFLIGIDKTKYAIA---CPIFAGLLHFFFLAAFAWMCLEGVQLYLMLVEVFESEYSRKK 938

Query: 230  MFICIGWGVPFPII-VAWAIGKLYYDNEK-CWFGKRPGVYTDYIYQGPMILVLLINFIFL 287
             +   G+  P  ++ V+ AI    Y  EK CW       Y  + + GP+  ++L+N IFL
Sbjct: 939  YYYVAGYLFPATVVGVSAAIDYKSYGTEKACWL--HVDNYFIWSFIGPVTFIILLNIIFL 996

Query: 288  FNIVRILMTKLRASTT-----SETIQYRKAVKATLVLLPLLGITYM--LFFVNPGEDEVS 340
               V  L   ++ S T     S     +  V     LL LLG+T+   L F+N  E  V 
Sbjct: 997  ---VITLCKMVKHSNTLKPDSSRLENIKSWVLGAFALLCLLGLTWSFGLLFINE-ETIVM 1052

Query: 341  RVVFIYFNSF 350
              +F  FN+F
Sbjct: 1053 AYLFTIFNAF 1062


>gi|40807489 egf-like module containing, mucin-like, hormone
           receptor-like sequence 1 [Homo sapiens]
          Length = 886

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 78/293 (26%), Positives = 130/293 (44%), Gaps = 41/293 (13%)

Query: 121 IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEV 180
           II+++G  ISLV L++A   FL  RSIR     +H +L    +L    +          +
Sbjct: 604 IISHVGIIISLVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLA-------GI 656

Query: 181 HQS-NVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAI----VLTYSTDRLRKWMFIC-I 234
           H++ N   C ++    +Y  +  FFWM  E   L   +    V+ Y + R  K + IC  
Sbjct: 657 HKTDNKMGCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAF 716

Query: 235 GWGVPFPIIV--AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVR 292
           G+G+P  ++V  A    + Y  + +CW     G    ++  GP+  V++IN + L   + 
Sbjct: 717 GYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFL--GPVCTVIVINSLLLTWTLW 774

Query: 293 ILMTKL-----RASTTSETIQYRKAVKATLVLLPLLGITYML--FFVNPGEDEVSRVVFI 345
           IL  +L       ST  +T   R         L +LG +++L  F + P    V   +F 
Sbjct: 775 ILRQRLSSVNAEVSTLKDT---RLLTFKAFAQLFILGCSWVLGIFQIGPVAG-VMAYLFT 830

Query: 346 YFNSFLESF----------QVRSAIRKRWHRWQDKHSIRARVARAM--SIPTS 386
             NS   +F          QVR    KRW   + K S +++ +R +  S+P++
Sbjct: 831 IINSLQGAFIFLIHCLLNGQVREEY-KRWITGKTKPSSQSQTSRILLSSMPSA 882


>gi|240120161 G protein-coupled receptor 144 [Homo sapiens]
          Length = 963

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 65/222 (29%), Positives = 99/222 (44%), Gaps = 26/222 (11%)

Query: 122 INYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVH 181
           ++++G  +S  AL   F+LFL     +  R  +H NL   F L +A  F+    M+ E  
Sbjct: 661 LSFVGCGVSFCALTTTFLLFLVAGVPKSERTTVHKNL--TFSLASAEGFL----MTSEWA 714

Query: 182 QSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFP 241
           ++N   C  VT A ++  +  F WM  EG  L   +V           ++   GWGVP  
Sbjct: 715 KANEVACVAVTVAMHFLFLVAFSWMLVEGLLLWRKVVAVSMHPGPGMRLYHATGWGVPVG 774

Query: 242 IIVAWAIGKLYYDNEK---CWFGKRPGVYTDYIYQ--GPMILVLLINFIFLFNIVRILMT 296
           I VA  +  L +D      CW      V+T+ I+   GP++ VL  N   L  +V I ++
Sbjct: 775 I-VAVTLAMLPHDYVAPGHCWLN----VHTNAIWAFVGPVLFVLTANTCILARVVMITVS 829

Query: 297 KLRASTTSET----------IQYRKAVKATLVLLPLLGITYM 328
             R      +           Q    VK  LVLLP+LG+T++
Sbjct: 830 SARRRARMLSPQPCLQQQIWTQIWATVKPVLVLLPVLGLTWL 871


>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
          Length = 1522

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 89/346 (25%), Positives = 150/346 (43%), Gaps = 66/346 (19%)

Query: 74   GVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINYLGHCISLVA 133
            G +   T+  + +CL +      +   + +EI+ E   +     V +I+     C++L+ 
Sbjct: 838  GCKTVLTDASHTKCLCDRLSTFAILAQQPREIIMESSGTP---SVTLIVGSGLSCLALIT 894

Query: 134  LLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTA 193
            L V +    R   IR  R+II  N   + I  N    ++ L    + H  ++  C   TA
Sbjct: 895  LAVVYAALWRY--IRSERSIILINFCLSIISSN----ILILVGQTQTHNKSI--CTTTTA 946

Query: 194  AYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIG---- 249
              ++F + +F W+  E    + A+     T  +RK  F+C+GWG+P  ++VA ++G    
Sbjct: 947  FLHFFFLASFCWVLTEAWQSYMAVTGKIRTRLIRK-RFLCLGWGLP-ALVVATSVGFTRT 1004

Query: 250  KLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINF---IFLFNIV----RILMTKL--RA 300
            K Y  +  CW     G+   Y + GP   V+L+N    I +FN +     IL  KL  RA
Sbjct: 1005 KGYGTDHYCWLSLEGGLL--YAFVGPAAAVVLVNMVIGILVFNKLVSRDGILDKKLKHRA 1062

Query: 301  STTSE-----TIQYRK-------AVKAT------------LVLLPLLGITYM--LFFVNP 334
               SE     T++  K       A+ AT             V+LPLL +T+M  +  +  
Sbjct: 1063 GQMSEPHSGLTLKCAKCGVVSTTALSATTASNAMASLWSSCVVLPLLALTWMSAVLAMTD 1122

Query: 335  GEDEVSRVVFIYFNSFLESF-----------QVRSAIRKRWHRWQD 369
                + +++F  F+S L+ F           +V+ A R R    QD
Sbjct: 1123 KRSILFQILFAVFDS-LQGFVIVMVHCILRREVQDAFRCRLRNCQD 1167


>gi|23397681 egf-like module containing, mucin-like, hormone
           receptor-like sequence 2 isoform a [Homo sapiens]
          Length = 823

 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 67/268 (25%), Positives = 113/268 (42%), Gaps = 28/268 (10%)

Query: 118 VAVIINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTMS 177
           V  +I Y+G  +SL+ LL+A + FL  ++I+     +H  L     L +  + V      
Sbjct: 535 VLTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTG 594

Query: 178 PEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYL----HTAIVLTYST-DRLRKWMFI 232
            +V       C ++    +Y ++    WM  E  YL        V+ YS+ +R  K +  
Sbjct: 595 HKV------LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMF 648

Query: 233 CIGWGVPFPIIVAWAIGK--LYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNI 290
            +G+GVP   +   A  +  LY    +CW     G    ++  GP+  +  +N +     
Sbjct: 649 PVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFL--GPVCAIFSVNLVLFLVT 706

Query: 291 VRILMTKLRASTTSETIQYRK----AVKATLVLLPLLGITYMLFFVNPG-EDEVSRVVFI 345
           + IL  +L +S  SE    R     A KAT  L  +LG T+ L  +  G    V   +F 
Sbjct: 707 LWILKNRL-SSLNSEVSTLRNTRMLAFKATAQLF-ILGCTWCLGILQVGPAARVMAYLFT 764

Query: 346 YFNS------FLESFQVRSAIRKRWHRW 367
             NS      FL    +   +R+++ +W
Sbjct: 765 IINSLQGVFIFLVYCLLSQQVREQYGKW 792


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.140    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,505,431
Number of Sequences: 37866
Number of extensions: 603588
Number of successful extensions: 1724
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 47
Number of HSP's that attempted gapping in prelim test: 1540
Number of HSP's gapped (non-prelim): 117
length of query: 401
length of database: 18,247,518
effective HSP length: 104
effective length of query: 297
effective length of database: 14,309,454
effective search space: 4249907838
effective search space used: 4249907838
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.